Personnel Information

写真a

YUKI Funauchi


Job title

Assistant Professor
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Graduating School 【 display / non-display 】

  • Tokyo Medical and Dental University, Faculty of Medicine, 2005.03, Graduated

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Graduate School 【 display / non-display 】

  • Tokyo Medical and Dental University, Doctor's Course, 2016.03, Completed

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Degree 【 display / non-display 】

  • Ph.D., Tokyo Medical and Dental University

  • M.D., Tokyo Medical and Dental University

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Campus Career 【 display / non-display 】

  • 2008.04
    -
    2016.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Advanced Therapeutic Sciences， Orthopaedic and Spinal Surgery， Graduate Student
  • 2021.04
    -
    2021.09
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Sensory, Orthopedic, and Dematologic Medicine， Orthopaedic Surgery， Assistant Professor
  • 2021.04
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Advanced Therapeutic Sciences， Orthopaedic and Spinal Surgery， Assistant Professor
  • 2021.10
    -
    Now
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Clinical Medicine， Department of Sensory, Orthopaedic, and Dermatologic Medicine， Orthopaedic Surgery， Assistant Professor
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Published Papers & Misc 【 display / non-display 】

  1. Masataka Motohashi, Yuki Funauchi, Takuya Adachi, Tomoyuki Fujioka, Naoya Otaka, Yuka Kamiko, Takashi Okada, Ukihide Tateishi, Atsushi Okawa, Toshitaka Yoshii, Shingo Sato. A New Deep Learning Algorithm for Detecting Spinal Metastases on Computed Tomography Images. Spine (Phila Pa 1976). 2024.03; 49 (6): 390-397. ( PubMed, DOI )

  2. Akane Ariga, Taisuke Tanizawa, Shingo Sato, Yuki Funauchi, Seiichi Matsumoto, Keisuke Ae. Bipolar Head Perforation With Rhabdomyosarcoma of the Thigh: A Case Report With Literature Review. Cancer Diagn Progn. 2024.01; 4 (1): 71-76. ( PubMed, DOI )

  3. Takumi Kaku, Yoto Oh, Shingo Sato, Hirotaka Koyanagi, Yuki Funauchi, Takashi Hirai, Masato Yuasa, Yu Matsukura, Toshitaka Yoshii, Tsuyoshi Nakagawa, Satoshi Miyake, Atsushi Okawa. Prevalence of Precursory Signs of Atypical Femoral Fractures in Patients Receiving Bone-Modifying Agents for Bone Metastases: A Cross-Sectional Study. JBMR Plus. 2023.07; 7 (7): e10749. ( PubMed, DOI )

  4. Takashi Hirai, Toshitaka Yoshii, Hiroyuki Inose, Yu Matsukura, Yuki Funauchi, Satoru Egawa, Kurando Utagawa, Jun Hashimoto, Mariko Nishizawa, Kohei Yamamoto, Atsushi Okawa. Intraosseous Aggressive Schwannoma in the Lumbar Spine: A Case Report. Spine Surg Relat Res. 2023.05; 7 (3): 288-292. ( PubMed, DOI )

  5. Takashi Hirai, Toshitaka Yoshii, Hiroyuki Inose, Yu Matsukura, Yuki Funauchi, Satoru Egawa, Kurando Utagawa, Jun Hashimoto, Mariko Nishizawa, Kohei Yamamoto, Atsushi Okawa. Intraosseous Aggressive Schwannoma In The Lumbar Spine: A Case Report Spine Surgery and Related Research. 2022.10; Article ID: 2022-0168.

  6. Ai Takemoto, Satoshi Takagi, Takao Ukaji, Nobuhiko Gyobu, Mamoru Kakino, Miho Takami, Asami Kobayashi, Marie Lebel, Tokuichi Kawaguchi, Minoru Sugawara, Kazue Tsuji-Takayama, Kenji Ichihara, Yuki Funauchi, Keisuke Ae, Seiichi Matsumoto, Yoshiya Sugiura, Kengo Takeuchi, Tetsuo Noda, Ryohei Katayama, Naoya Fujita. Targeting Podoplanin for the Treatment of Osteosarcoma. Clin Cancer Res. 2022.06; 28 (12): 2633-2645. ( PubMed, DOI )

  7. Kyoko Yamashita, Yuki Funauchi, Keiko Hayakawa, Keisuke Ae, Seiichi Matsumoto, Kunihiro Ikuta, Yoshihiro Nishida, Teruko Ueno, Yoshie Shimoyama, Nobuyuki Hiruta, Rikuo Machinami, Hiroshi Kawachi, Kengo Takeuchi. S100-negative epithelioid malignant peripheral nerve sheath tumor with possible perineurial differentiation. Virchows Arch. 2022.06; 480 (6): 1269-1275. ( PubMed, DOI )

  8. Yasuyoshi Sato, Kenji Nakano, Xiaofei Wang, Naoki Fukuda, Tetsuya Urasaki, Akihiro Ohmoto, Naomi Hayashi, Mayu Yunokawa, Makiko Ono, Junichi Tomomatsu, Masanori Saito, Yusuke Minami, Keiko Hayakawa, Yuki Funauchi, Taisuke Tanizawa, Keisuke Ae, Seiichi Matsumoto, Shunji Takahashi. Pre-Treatment Neutrophil-to-Lymphocyte Ratio (NLR) as a Predictive Marker of Pazopanib Treatment for Soft-Tissue Sarcoma. Cancers (Basel). 2021.12; 13 (24): 6266. ( PubMed, DOI )

  9. Satoshi Takagi, Yuki Sasaki, Sumie Koike, Ai Takemoto, Yosuke Seto, Mizuki Haraguchi, Takao Ukaji, Tokuichi Kawaguchi, Minoru Sugawara, Masanori Saito, Yuki Funauchi, Keisuke Ae, Seiichi Matsumoto, Naoya Fujita, Ryohei Katayama. Platelet-derived lysophosphatidic acid mediated LPAR1 activation as a therapeutic target for osteosarcoma metastasis. Oncogene. 2021.09; 40 (36): 5548-5558. ( PubMed, DOI )

  10. Yasuyoshi Sato, Kenji Nakano, Kuniki Kawaguchi, Naoki Fukuda, Xiaofei Wang, Tetsuya Urasaki, Akihiro Ohmoto, Naomi Hayashi, Mayu Yunokawa, Makiko Ono, Junichi Tomomatsu, Keiko Hayakawa, Yuki Funauchi, Taisuke Tanizawa, Keisuke Ae, Seiichi Matsumoto, Shunji Takahashi. Changes in Neutrophil-to-lymphocyte Ratio Predict Efficacy of Trabectedin for Soft-tissue Sarcoma. Cancer Diagn Progn. 2021.07; 1 (4): 303-308. ( PubMed, DOI )

  11. Sermsak Sukpanichyingyong, Seiichi Matsumoto, Keisuke Ae, Taisuke Tanizawa, Keiko Hayakawa, Yuki Funauchi, Yusuke Minami, Masanori Saito, Joji Miyawaki. Surgical Treatment of Intramuscular Myxoma. Indian J Orthop. 2021.02; 55 (4): 892-897. ( PubMed, DOI )

  12. Kenji Nakano, Keiko Hayakawa, Yuki Funauchi, Taisuke Tanizawa, Keisuke Ae, Seiichi Matsumoto, Junichi Tomomatsu, Makiko Ono, Shinichiro Taira, Masatoshi Nishizawa, Xiaofei Wang, Akihiro Ohmoto, Yasuyoshi Sato, Naoki Fukuda, Tetsuya Urasaki, Shunji Takahashi. Differences in the efficacy and safety of eribulin in patients with soft tissue sarcoma by histological subtype and treatment line. Mol Clin Oncol. 2021.01; 14 (1): 13. ( PubMed, DOI )

  13. Yasuyoshi Sato, Kenji Nakano, Naoki Fukuda, Xiaofei Wang, Tetsuya Urasaki, Akihiro Ohmoto, Mayu Yunokawa, Makiko Ono, Junichi Tomomatsu, Keiko Hayakawa, Yuki Funauchi, Taisuke Tanizawa, Keisuke Ae, Seiichi Matsumoto, Shunji Takahashi. Pre-treatment Neutrophil-to-Lymphocyte Ratio Predicts Efficacy of Eribulin for Soft-tissue Sarcoma. Anticancer Res. 2021.01; 41 (1): 527-532. ( PubMed, DOI )

  14. Sasaki T, Gokita T, Ae K, Tanizawa T, Hayakawa K, Funauchi Y, Motoi N, Matsumoto S. Osteosarcoma arising from acetabulum extended to femoral head through round ligament: a case report. Oxford medical case reports. 2020.11; 2020 (11): omaa076. ( PubMed, DOI )

  15. Hayakawa K, Matsumoto S, Ae K, Tanizawa T, Funauchi Y, Minami Y, Saito M, Okawa A. Definitive surgery of primary lesion should be prioritized over preoperative chemotherapy to treat high-grade osteosarcoma in patients aged 41-65 years. Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology. 2020.08; 21 (1): 13. ( PubMed, DOI )

  16. Sukpanichyingyong S, Matsumoto S, Ae K, Tanizawa T, Hayakawa K, Funauchi Y, Minami Y, Saito M, Yamashita K. Simultaneous bifocal and asymptomatic intramuscular nodular fasciitis of the thigh: A case report. Clinical case reports. 2020.07; 8 (7): 1213-1216. ( PubMed, DOI )

  17. Minami Y, Matsumoto S, Ae K, Tanizawa T, Hayakawa K, Funauchi Y, Saito M. The Extracompartmental Tumoral Invasion of Extraskeletal Myxoid Chondrosarcoma Induces Distant Metastasis. Anticancer research. 2020.02; 40 (2): 1035-1039. ( PubMed, DOI )

  18. Minami Y, Matsumoto S, Ae K, Tanizawa T, Hayakawa K, Funauchi Y, Saito M, Tsuda Y. The Role of Neoadjuvant Chemotherapy in Resectable Primary Synovial Sarcoma. Anticancer research. 2020.02; 40 (2): 1029-1034. ( PubMed, DOI )

  19. Teramura Y, Yamazaki Y, Tanaka M, Sugiura Y, Takazawa Y, Takeuchi K, Nakayama T, Kaneko T, Musha Y, Funauchi Y, Ae K, Matsumoto S, Nakamura T. Case of mesenchymal tumor with the PPP6R3-USP6 fusion, possible nodular fasciitis with malignant transformation. Pathology international. 2019.12; 69 (12): 706-709. ( PubMed, DOI )

  20. 早川 景子, 阿江 啓介, 谷澤 泰介, 船内 雄生, 三浪 友輔, 齊藤 正徳, 西村 英樹, 田村 聡至, 辻 利奈, 松本 誠一. 小児AYA世代骨軟部腫瘍患者に対する妊孕性温存の取り組みについて 日本癌治療学会学術集会抄録集. 2019.10; 57回 O70-2. ( ichushi )

  21. 船内 雄生, 三浪 友輔, 早川 景子, 谷澤 泰介, 松本 誠一, 阿江 啓介. 表在性軟部肉腫(UPS/MFS)の臨床的特徴と予後　深部発生例との比較 日本癌治療学会学術集会抄録集. 2019.10; 57回 O69-2. ( ichushi )

  22. 早川 景子, 阿江 啓介, 谷澤 泰介, 船内 雄生, 三浪 友輔, 齊藤 正徳, 西村 英樹, 田村 聡至, 辻 利奈, 松本 誠一. 小児AYA世代骨軟部腫瘍患者に対する妊孕性温存の取り組みについて 日本癌治療学会学術集会抄録集. 2019.10; 57回 O70-2.

  23. 船内 雄生, 三浪 友輔, 早川 景子, 谷澤 泰介, 松本 誠一, 阿江 啓介. 表在性軟部肉腫(UPS/MFS)の臨床的特徴と予後 深部発生例との比較 日本癌治療学会学術集会抄録集. 2019.10; 57回 O69-2.

  24. Sekimizu M, Yoshida A, Mitani S, Asano N, Hirata M, Kubo T, Yamazaki F, Sakamoto H, Kato M, Makise N, Mori T, Yamazaki N, Sekine S, Oda I, Watanabe SI, Hiraga H, Yonemoto T, Kawamoto T, Naka N, Funauchi Y, Nishida Y, Honoki K, Kawano H, Tsuchiya H, Kunisada T, Matsuda K, Inagaki K, Kawai A, Ichikawa H. Frequent mutations of genes encoding vacuolar H<sup>+</sup> -ATPase components in granular cell tumors. Genes, chromosomes & cancer. 2019.06; 58 (6): 373-380. ( PubMed, DOI )

  25. Nakano K, Funauchi Y, Hayakawa K, Tanizawa T, Ae K, Matsumoto S, Takahashi S. Relative Dose Intensity of Induction-Phase Pazopanib Treatment of Soft Tissue Sarcoma: Its Relationship with Prognoses of Pazopanib Responders. Journal of clinical medicine. 2019.01; 8 (1): ( PubMed, DOI )

  26. Kito M, Matsumoto S, Ae K, Tanizawa T, Gokita T, Hayakawa K, Funauchi Y, Yamamoto N. Giant cell tumor of the distal femur: Outcome beyond 20 years of follow-up after curettage with polymethylmethacrylate. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association. 2018.11; 23 (6): 1051-1055. ( PubMed, DOI )

  27. Minami Y, Matsumoto S, Ae K, Tanizawa T, Hayakawa K, Funauchi Y, Okumura S, Takazawa Y. Successful Complete Response of Tumor Thrombus after Combined with Chemotherapy and Irradiation for Ewing Sarcoma. Case reports in orthopedics. 2018; 2018 5238512. ( PubMed, DOI )

  28. Kito M, Matsumoto S, Ae K, Tanizawa T, Gokita T, Hayakawa K, Funauchi Y, Takazawa Y. Multicentric giant cell tumor of bone: Case series of 4 patients. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association. 2017.11; 22 (6): 1107-1111. ( PubMed, DOI )

  29. Tanikawa C, Zhang YZ, Yamamoto R, Tsuda Y, Tanaka M, Funauchi Y, Mori J, Imoto S, Yamaguchi R, Nakamura Y, Miyano S, Nakagawa H, Matsuda K. The Transcriptional Landscape of p53 Signalling Pathway. EBioMedicine. 2017.06; 20 109-119. ( PubMed, DOI )

  30. Kito M, Matusmoto S, Ae K, Tanizawa T, Gokita T, Kobayashi H, Hayakawa K, Funauchi Y. Pulmonary metastasis from giant cell tumor of bone: clinical outcome prior to the introduction of molecular target therapy. Japanese journal of clinical oncology. 2017.06; 47 (6): 529-534. ( PubMed, DOI )

  31. Mori J, Tanikawa C, Ohnishi N, Funauchi Y, Toyoshima O, Ueda K, Matsuda K. EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis. Neoplasia (New York, N.Y.). 2017.03; 19 (3): 185-195. ( PubMed, DOI )

  32. 三浪 友輔, 松本 誠一, 阿江 啓介, 谷澤 泰介, 五木田 茶舞, 早川 景子, 船内 雄生, 鬼頭 宗久, 角 優介, 杉浦 善弥. 滑膜肉腫手術例におけるFNCLCC gradeと予後の関係について 日本癌学会総会記事. 2016.10; 75回 P-3286. ( ichushi )

  33. Hayakawa K, Matsumoto S, Ae K, Tanizawa T, Gokita T, Funauchi Y, Motoi N. Risk factors for distant metastasis of dermatofibrosarcoma protuberans. Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology. 2016.09; 17 (3): 261-6. ( PubMed, DOI )

  34. Mori J, Tanikawa C, Funauchi Y, Lo PH, Nakamura Y, Matsuda K. Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity. Cancer science. 2016.03; 107 (3): 298-306. ( PubMed, DOI )

  35. Funauchi Y, Tanikawa C, Yi Lo PH, Mori J, Daigo Y, Takano A, Miyagi Y, Okawa A, Nakamura Y, Matsuda K. Regulation of iron homeostasis by the p53-ISCU pathway. Scientific reports. 2015.11; 5 16497. ( PubMed, DOI )

  36. 森 甚一, 谷川 千津, Lo Paulisally H.Y., 船内 雄生, 中村 祐輔, 松田 浩一. p53による細胞骨格制御(Regulation of cytoskeleton by p53) 日本癌学会総会記事. 2014.09; 73回 P-2073. ( ichushi )

  37. 船内 雄生, 谷川 千津, 盧 巧兒, 田中 正視, 森 甚一, 醍醐 弥太郎, 高野 淳, 宮城 洋平, 中村 祐輔, 松田 浩一. p53はISCUの発現誘導を介して生体内鉄恒常性の維持に関与する(Regulation of iron homeostasis by p53-ISCU pathway) 日本癌学会総会記事. 2014.09; 73回 J-2054. ( ichushi )

  38. 船内 雄生, 谷川 千津, Lo Paulisally, 田中 正視, 森 甚一, 中村 祐輔, 松田 浩一. p53はp53IRIの発現誘導を介して細胞内鉄量の調節に関与する(p53 regulates intracellular iron metabolism through the regulation of p53IRI) 日本癌学会総会記事. 2013.10; 72回 104. ( ichushi )

  39. 森 甚一, Lo Paulisally H.Y., 植田 幸嗣, 谷川 千津, 田中 正視, 船内 雄生, 中川 英刀, 中村 祐輔, 松田 浩一. プロテオーム解析を用いたp53下流タンパクの同定(Identification of novel p53-targets by using proteomic analysis) 日本癌学会総会記事. 2013.10; 72回 104. ( ichushi )

  40. Koyanagi H, Ae K, Maehara H, Yuasa M, Masaoka T, Yamada T, Taniyama T, Saito M, Funauchi Y, Yoshii T, Okawa A, Sotome S. Massive bone reconstruction with heat-treated bone graft loaded autologous bone marrow-derived stromal cells and β-tricalcium phosphate composites in canine models. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2013.08; 31 (8): 1308-16. ( PubMed, DOI )

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