Personnel Information

写真a

Ozeki Nobutake


Job title

Junior Associate Professor

Graduating School 【 display / non-display

  • Shiga University of Medical Science, Faculty of Medicine, 2002.03, Graduated

Graduate School 【 display / non-display

  • Yokohama City University, Graduate School, Division of Medical Science, Doctor's Course, 2014.03, Completed

Campus Career 【 display / non-display

  • 2015.03
    -
    2017.03
    Tokyo Medical and Dental University, Research and Industry-University Alliance Organization, Center for Stem Cell and Regenerative Medicine, Assistant Professor
  • 2017.04
    -
    2018.03
    Tokyo Medical and Dental University, Institute of Research, Division of Advanced Research, Center for Stem Cell and Regenerative Medicine, Assistant Professor
  • 2018.04
    -
    2018.05
    Tokyo Medical and Dental University, Institute of Research, Assistant Professor
  • 2018.06
    -
    2020.06
    Tokyo Medical and Dental University, Institute of Research, Division of Advanced Research, Center for Stem Cell and Regenerative Medicine, Assistant Professor
  • 2020.07
    -
    2022.02
    Tokyo Medical and Dental University, Institute of Research, Division of Advanced Research, Center for Stem Cell and Regenerative Medicine, Assistant Professor
  • 2020.07
    -
    2022.04
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Applied Regenerative Medicine, Assistant Professor
  • 2022.03
    -
    2022.04
    Tokyo Medical and Dental University, Institute of Research, a, Center for Stem Cell and Regenerative Medicine, Assistant Professor
  • 2022.05
    -
    Now
    Tokyo Medical and Dental University, Institute of Research, a, Center for Stem Cell and Regenerative Medicine, Junior Associate Professor
  • 2022.05
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Applied Regenerative Medicine, Junior Associate Professor

▼display all

Research Areas 【 display / non-display

  • Orthopedics

Qualification Acquired 【 display / non-display

  • Doctor

 

Published Papers & Misc 【 display / non-display

  1. Yusuke Fuchioka, Kentaro Endo, Yuriko Sakamaki, Takahiro Tanimoto, Nobutake Ozeki,Yusuke Nakagawa, Hideyuki Koga, Makoto Tomita, Ichiro Sekiya.. Scanning electron microscopy analysis of synovial and adipose mesenchymal stem cells adhering to cartilage Regenerative Therapy. 2024.12; 27 488-495. ( PubMed, DOI )

  2. Seiya Matsuta, Kentaro Endo, Nobutake Ozeki, Yusuke Nakagawa, Hideyuki Koga, Ichiro Sekiya. Synovial mesenchymal stem cells secrete more lubricin than adipose mesenchymal stem cells after injection into rat osteoarthritis knees. Biochem Biophys Res Commun. 2024.07; 729 150354. ( PubMed, DOI )

  3. Tetsuya Tachibana, Hiroki Katagiri, Junpei Matsuda, Nobutake Ozeki, Toshifumi Watanabe, Ichiro Sekiya, Tetsuya Jinno. Biomechanical analysis of load distribution in porcine hip joints at different acetabular coverages. BMC Musculoskelet Disord. 2024.07; 25 (1): 576. ( PubMed, DOI )

  4. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Hiroki Katagiri, Yusuke Nakagawa, Takashi Hoshino, Mai Katakura, Masaki Amemiya, Aritoshi Yoshihara, Hisako Katano, Mitsuru Mizuno, Kentaro Endo, Jun Masumoto, Ichiro Sekiya. Cartilage thickness in the medial compartment of the knee joint evaluated by MRI three-dimensional analysis correlates with weight-bearing line ratio and joint line convergence angle. J Orthop Sci. 2024.07; ( PubMed, DOI )

  5. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Hiroki Katagiri, Yusuke Nakagawa, Takashi Hoshino, Mai Katakura, Masaki Amemiya, Aritoshi Yoshihara, Hisako Katano, Mitsuru Mizuno, Kentaro Endo, Jun Masumoto, Ichiro Sekiya. The association of the medial meniscus covering ratio with knee cartilage thickness at 15 medial compartment subregions as found by three-dimensional analysis using MRI. J Exp Orthop. 2024.07; 11 (3): e70005. ( PubMed, DOI )

  6. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Yusuke Nakagawa, Takashi Hoshino, Masaki Amemiya, Ichiro Sekiya. Real-Time Virtual Sonography-Guided Ossicle Removal in Unresolved Osgood-Schlatter Disease. Arthrosc Tech. 2024.04; 13 (4): 102897. ( PubMed, DOI )

  7. Mitsuru Mizuno, Yoshitaka Maeda, Sho Sanami, Takahisa Matsuzaki, Hiroshi Y Yoshikawa, Nobutake Ozeki, Hideyuki Koga, Ichiro Sekiya. Noninvasive total counting of cultured cells using a home-use scanner with a pattern sheet. iScience. 2024.03; 27 (3): 109170. ( PubMed, DOI )

  8. Hisako Katano, Nobutake Ozeki, Mitsuru Mizuno, Kentaro Endo, Noriya Okanouchi 1,2, Jo Fujita, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya. Morphological analysis of three-dimensional MR images of patellofemoral joints in asymptomatic subjects Sci Rep. 2023.12;

  9. Hao Ding, Hideyuki Koga, Hiroki Katagiri, Shoichi Hasegawa, Tatushiko Anzai, Mai Katakura, Aritoshi Yoshihara, Masaki Amemiya, Takashi Hoshino, Nobutake Ozeki, Tomomasa Nakamura, Yusuke Nakagawa. Low central sensitisation inventory score is associated with better post-operative outcomes of osteotomy around the knee. Knee Surg Sports Traumatol Arthrosc. 2023.12; 31 (12): 5896-5904. ( PubMed, DOI )

  10. Amano Y, Ozeki N, Matsuda J, Nakamura T, Nakagawa Y, Sekiya I, Koga H. Augmentation of a Nonanatomical Repair of a Medial Meniscus Posterior Root Tear With Centralization Using Three Knotless Anchors May Be Associated With Less Meniscal Extrusion and Better Compressive Load Distribution in Mid-Flexion Compared With Non-Anatomical Root Repair Alone in a Porcine Knee Model. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 2023.12; 39 (12): 2487-2498.e4. ( PubMed, DOI )

  11. Ozeki Nobutake, Nakamura Tomomasa, Nakagawa Yusuke, Sekiya Ichiro, Koga Hideyuki. Meniscus repair and centralization: Preserving meniscus function Journal of Joint Surgery and Research. 2023.12; 1 (1): 46-55. ( DOI ichushi )

  12. Yusuke Nakagawa, Hideyuki Koga, Tomomasa Nakamura, Masafumi Horie, Hiroki Katagiri, Nobutake Ozeki, Toshiyuki Ohara, Ichiro Sekiya, Takeshi Muneta, Toshifumi Watanabe. Mid-term clinical outcomes of a posterior stabilized total knee prosthesis for Japanese patients: A minimum follow-up of 5 years. J Orthop Sci. 2023.11; 28 (6): 1325-1330. ( PubMed, DOI, ichushi )

  13. Ichiro Sekiya, Hisako Katano, Ali Guermazi, Yugo Miura, Noriya Okanouchi, Makoto Tomita, Jun Masumoto, Yoshio Kitazume, Hideyuki Koga, Nobutake Ozeki. Association of AI-determined Kellgren-Lawrence grade with medial meniscus extrusion and cartilage thickness by AI-based 3D MRI analysis in early knee osteoarthritis. Sci Rep. 2023.11; 13 (1): 20093. ( PubMed, DOI )

  14. Katano, H; Ozeki, N; Mizuno, M; Endo, K; Okanouchi, N; Fujita, J; Masumoto, J; Koga, H; Sekiya, I. Morphological analysis of three-dimensional MR images of patellofemoral joints in asymptomatic subjects SCIENTIFIC REPORTS. 2023.10; 13 (1): 16750. ( PubMed, DOI )

  15. Nobutake Ozeki, Hideyuki Koga, Yusuke Nakagawa, Hiroki Katagiri, Hisako Katano, Makoto Tomita, Jun Masumoto, Ichiro Sekiya. Association between knee cartilage thickness determined by magnetic resonance imaging three-dimensional analysis and the International Cartilage Repair Society (ICRS) arthroscopic grade. Knee. 2023.06; 42 90-98. ( PubMed, DOI )

  16. Hiroki Katagiri, Yusuke Nakagawa, Yusuke Amano, Yoshiko Shirakawa, Nobutake Ozeki, Tomomasa Nakamura, Ichiro Sekiya, Hideyuki Koga. Decision regret following opening wedge high tibial osteotomy: Older age as a risk factor. Knee. 2023.06; 43 62-69. ( PubMed, DOI )

  17. Katagiri, H; Nakagawa, Y; Miyatake, K; Ozeki, N; Kohno, Y; Amemiya, M; Sekiya, I; Koga, H. Comparison of Clinical Outcomes after Revision Anterior Cruciate Ligament Reconstruction using a Bone-patellar Tendon-bone Autograft and that Using a Double-Bundle Hamstring Tendon Autograft JOURNAL OF KNEE SURGERY. 2023.05; 36 (06): 613-621. ( PubMed, DOI )

  18. Yusuke Nakagawa, Kunikazu Tsuji, Tomomasa Nakamura, Hiroki Katagiri, Nobutake Ozeki, Mikio Shioda, Jae-Sung An, Ryu Yoshida, Ichiro Sekiya, Hideyuki Koga. Association of Infrapatellar Fat Pad Fibrosis at 3 Months After ACL Reconstruction With Short-term Clinical Outcomes and Inflammatory Cytokine Levels in the Synovial Fluid. Orthop J Sports Med. 2023.04; 11 (4): 23259671231164122. ( PubMed, DOI )

  19. Nobutake Ozeki, Mitsuru Mizuno, Shinobu Yanada, Takuya Okada, Rei Kubota, Yoshihisa Kushida, Hideto Furuoka, Kentaro Endo, Hisako Katano, Kentaro Nakamura, Shoji Ohya, Hideyuki Koga, Ichiro Sekiya. Autologous Synovial Mesenchymal Stem Cell Transplantation Suppresses Inflammation Caused by Synovial Harvesting and Promotes Healing in a Micro Minipig Repaired Meniscus Model. Transplant Proc. 2023.03; 55 (2): 470-480. ( PubMed, DOI )

  20. Fujii T, Yoneyama Y, Kinebuchi A, Ozeki N, Maeda S, Saiki N, Chen-Yoshikawa TF, Date H, Nishiwaki K, Takebe T. Enteral liquid ventilation oxygenates a hypoxic pig model. iScience. 2023.03; 26 (3): 106142. ( PubMed, DOI )

  21. Ariga, A; Kohno, Y; Nakagawa, Y; Watanabe, T; Katagiri, H; Ohara, T; Shioda, M; Ozeki, N; Amemiya, M; Okawa, A; Sekiya, I; Koga, H. Simultaneous bilateral total knee arthroplasty is safe and effective for patients in different ages JOURNAL OF ORTHOPAEDIC SCIENCE. 2023.01; 28 (1): 173-179. ( PubMed, DOI, ichushi )

  22. Shunichi Fujii, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya. Comparison of adhesion of thawed and cultured synovial mesenchymal stem cells to the porcine meniscus and the relevance of cell surface microspike BMC Molecular and Cell Biology. 2022.12; 23 (1): 53. ( PubMed, DOI )

  23. Mizuno Mitsuru, Ozeki Nobutake, Sekiya Ichiro. 変形性関節症に対する細胞療法でトリソミー7を有する培養細胞を使用する場合の安全性(Safety of using cultured cells with trisomy 7 in cell therapy for treating osteoarthritis) Regenerative Therapy. 2022.12; 21 81-86. ( ichushi )

  24. Hideyuki Koga, Tomomasa Nakamura, Yusuke Nakagawa, Nobutake Ozeki, Takashi Hoshino, Masaki Amemiya, Ichiro Sekiya. Simultaneous Correction of Varus Deformity and Posterior Tibial Slope by Modified Hybrid Closed-Wedge High Tibial Osteotomy. Arthrosc Tech. 2022.11; 11 (11): e2081-e2089. ( PubMed, DOI )

  25. Takahiro Tanimoto, Kentaro Endo, Yuriko Sakamaki, Nobutake Ozeki, Hisako Katanom, Mitsuru Mizuno, Hideyuki Koga, Ichiro Sekiya .. Human synovial mesenchymal stem cells show time-dependent morphological changes and increased adhesion to degenerated porcine cartilage. Scientific Reports. 2022.10; 12 (1): 16619. ( PubMed, DOI )

  26. Ichiro Sekiya, Nobutake Ozeki. The 16th International Workshop on Osteoarthritis Imaging:“New insightson treatment and imaging: A :couple that belongs together" Osteoarthritis Imaging. 2022.10; Volume 2 (Supplement 1):

  27. Hiroki Katagiri, Mikio Shioda, Yusuke Nakagawa, Toshiyuki Ohara, Nobutake Ozeki, Tomomasa Nakamura, Ichiro Sekiya, Hideyuki Koga. Risk Factors Affecting Return to Sports and Patient-Reported Outcomes After Opening-Wedge High Tibial Osteotomy in Active Patients. Orthop J Sports Med. 2022.09; 10 (9): 23259671221118836. ( PubMed, DOI )

  28. Ichiro Sekiya, Sho Sasaki, Yugo Miura, Hayato Aoki, Hisako Katano, Noriya Okanouchi, Makoto Tomita, Jun Masumoto, Hideyuki Koga, Nobutake Ozeki. Medial Tibial Osteophyte Width Strongly Reflects Medial Meniscus Extrusion Distance and Medial Joint Space Width Moderately Reflects Cartilage Thickness in Knee Radiographs. J Magn Reson Imaging. 2022.09; 56 (3): 824-834. ( PubMed, DOI )

  29. Sekiya Ichiro, Koga Hideyuki, Katano Hisako, Mizuno Mitsuru, Kohno Yuji, Otabe Koji, Ozeki Nobutake. 半月板修復術と滑膜間葉幹細胞移植による内側半月板の変性フラップおよび放射状断裂治療後のセカンドルック関節鏡検査 症例報告(Second-look arthroscopy after meniscus repair and synovial mesenchymal stem cell transplantation to treat degenerative flaps and radial tears of the medial meniscus: A case report) Journal of Orthopaedic Science. 2022.07; 27 (4): 821-834. ( ichushi )

  30. Mituru Mizunoi,Nobutake Ozeki,Ichiro Sekiya.. Safety of using cultured cells with trisomy 7 in cell therapy for treating osteoarthritis Regenerative Therapy. 2022.06; 17 (21): 81-86. ( PubMed, DOI )

  31. Mituru Mizuno,Takahisa Matsuzaki,Nobutake Ozeki,Hisako Katano,Hideyuki Koga,Takanori Takebe,Hiroshi Yoshikawa,Ichiro Sekiya. Cell membrane fluidity and ROS resistance define DMSO tolerance of cryopreserved synovial MSCs and HUVECs. Stem Cell Research & Therapy. 2022.05; 13 (1): 177. ( PubMed, DOI )

  32. Sekiya I, Koga H, Katano H, Mizuno M, Kohno Y, Otabe K, Ozeki N. . Second-look arthroscopy after meniscus repair and synovial mesenchymal stem cell transplantation to treat degenerative flaps and radial tears of the medial meniscus: J Orthop Sci. 2022.05; 27 (4): 821-834. ( PubMed, DOI )

  33. Yuji Kohno, Hideyuki Koga, Nobutake Ozeki, Junpei Matsuda, Mitsuru Mizuno, Hisako Katano, Ichiro Sekiya. Biomechanical analysis of a centralization procedure for extruded lateral meniscus after meniscectomy in porcine knee joints. Journal Orthopaedic Research. 2022.05; 40 (5): 1097-1103. ( PubMed, DOI )

  34. Yusuke Nakagawa, Nobutake Ozeki, Hideyuki Koga.. A narrative review of lateral meniscus root tears and extrusion: techniques and outcomes. Ann Joint.. 2022.04; 7 15. ( PubMed, DOI )

  35. Nobutake Ozeki, Hideyuki Koga, Ichiro Sekiya. Degenerative meniscus in knee osteoarthritis: from pathology to treatment. life. 2022.04; 12 (4): 603. ( PubMed, DOI )

  36. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Yusuke Nakagawa, Toshiyuki Ohara, Jae-Sung An, Ichiro Sekiya. Ultrasound-assisted arthroscopic all-inside repair technique for posterior lateral meniscus tear. Arthroscopy Techniques. 2022.04; 11 (5): e929-e935. ( PubMed, DOI )

  37. Yuji Kohno, Mitsuru Mizuno, Kentaro Endo, Nobutake Ozeki, Hisako Katano, Mikio Matsumoto, Haruka Kaneko, Yuji Takazawa, Hideyuki Koga, Ichiro Sekiya. Yields of mesenchymal stromal cells from synovial fluid reflect those from synovium in patients with rheumatoid arthritis Tissue and Cell. 2022.04; 75 101727. ( PubMed, DOI )

  38. Hisako Katano, Nobutake Ozeki, Hideyuki Koga, Makoto Tomita, Kenji Suzuki, Jun Masumoto, Ichiro Sekiya.. Three-dimensional MRI shows cartilage defect extension with no separation from the meniscus in women in their 70s with knee osteoarthritis. Sci Rep.(Scientific Reports). 2022.03; 12 (1): 4198. ( PubMed, DOI )

  39. Yugo Miura, Nobutake Ozeki, Hisako Katano, Hayato Aoki, Noriya Okanouchi, Makoto Tomita, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya. Difference in the joint space of the medial knee compartment between full extension and Rosenberg weight-bearing radiographs. Eur Radiol. 2022.03; 32 (3): 1429-1437. ( PubMed, DOI )

  40. Hisako Katano, Nobutake Ozeki, Hideyuki Koga, Kenji Suzuki, Jun Masumoto, Makoto Tomita, Ichiro Sekiya. Interscan measurement error in measurements of the meniscus, including the meniscal roots, by fully automatic three-dimensional MRI analysis. Osteoarthritis Imaging.. 2022.03; 2 (1): ( DOI )

  41. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Yusuke Nakagawa, Toshiyuki Ohara, Yuji Kohno, Ichiro Sekiya. Surgical Repair of Symptomatic Wrisberg Variant Discoid Lateral Mensicus with Pull-Out Repair and Capsulodesis. Arthrosc Tech. 2021.12; 11 (1): e61-e68. ( PubMed, DOI )

  42. Mitsuru Mizuno, Kentaro Endo, Hisako Katano, Naoki Amano, Masaki Nomura, Yoshinori Hasegawa, Nobutake Ozeki, Hideyuki Koga, Naoko Takasu, Osamu Ohara, Tomohiro Morio, Ichiro Sekiya. Transplantation of human autologous synovial mesenchymal stem cells with trisomy 7 into the knee joint and 5 years of follow-up. Stem Cells Transl Med. 2021.11; 10 (11): 1530-1543. ( PubMed, DOI )

  43. Kentaro Endo, Kiyotaka Horiuchi, Hisako Katano, Nobutake Ozeki, Yuriko Sakamaki, Hideyuki Koga, Ichiro Sekiya. Intra-articular Injection of PDGF-BB Explored in a Novel in Vitro Model Mobilizes Mesenchymal Stem Cells From the Synovium Into Synovial Fluid in Rats. Stem Cell Rev Rep. 2021.10; 17 (5): 1768-1779. ( PubMed, DOI )

  44. Hisako Katano, Nobutake Ozeki, Yuji Kohno, Yusuke Nakagawa, Hideyuki Koga, Toshifumi Watanabe, Tetsuya Jinno, Ichiro Sekiya. Trends in arthroplasty in Japan by a complete survey, 2014-2017. J Orthop Sci. 2021.09; 26 (5): 812-822. ( PubMed, DOI, ichushi )

  45. Misaki Yagi, Mitsuru Mizuno, Ryota Fujisawa, Hisako Katano, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Hideyuki Koga, Ichiro Sekiya. Optimal Pore Size of Honeycomb Polylactic Acid Films for In Vitro Cartilage Formation by Synovial Mesenchymal Stem Cells. Stem Cells Int. 2021.08; 2021 9239728. ( PubMed, DOI )

  46. Takashi Hoshino, Toshifumi Watanabe, Yusuke Nakagawa, Hiroki Katagiri, Nobutake Ozeki, Toshiyuki Ohara, Mikio Shioda, Yuji Kono, Ichiro Sekiya, Hideyuki Koga. Clinical outcomes of two-stage revision total knee arthroplasty in infected cases with antibiotic-loaded cement spacers produced using a handmade silicone mold. Knee Surg Relat Res. 2021.08; 33 (1): 27. ( PubMed, DOI )

  47. Ichiro Sekiya, Hisako Katano, Mitsuru Mizuno, Hideyuki Koga, Jun Masumoto, Makoto Tomita, Nobutake Ozeki. Alterations in cartilage quantification before and after injections of mesenchymal stem cells into osteoarthritic knees. Sci Rep. 2021.07; 11 (1): 13832. ( PubMed, DOI )

  48. Nobutake Ozeki, Yusuke Nakagawa, Mitsuru Mizuno, Yuji Kohno, Hisako Katano, Hideyuki Koga, Ichiro Sekiya. Ultrasound-Guided Harvesting of Synovium for Regenerative Medicine of Cartilage and Meniscus Using Synovial Mesenchymal Stem Cells. Arthrosc Tech. 2021.07; 10 (7): e1723-e1727. ( PubMed, DOI )

  49. Ichiro Sekiya, Yuji Kohno, Akinobu Hyodo, Hisako Katano, Keiichiro Komori, Hideyuki Koga, Makoto Tomita, Kenji Suzuki, Jun Masumoto, Nobutake Ozeki. Interscan measurement error of knee cartilage thickness and projected cartilage area ratio at 9 regions and 45 subregions by fully automatic three-dimensional MRI analysis. Eur J Radiol. 2021.06; 139 109700. ( PubMed, DOI )

  50. Kiyotaka Horiuchi, Nobutake Ozeki, Kentaro Endo, Mitsuru Mizuno, Hisako Katano, Masako Akiyama, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya. Thawed cryopreserved synovial mesenchymal stem cells show comparable effects to cultured cells in the inhibition of osteoarthritis progression in rats. Sci Rep. 2021.05; 11 (1): 9683. ( PubMed, DOI )

  51. Hideyuki Koga, Tomomasa Nakamura, Yusuke Nakagawa, Nobutake Ozeki, Toshiyuki Ohara, Mikio Shioda, Yuji Kohno, Masaki Amemiya, Ichiro Sekiya. Arthroscopic Centralization Using Knotless Anchors for Extruded Medial Meniscus. Arthrosc Tech. 2021.03; 10 (3): e639-e645. ( PubMed, DOI )

  52. Ichiro Sekiya, Hisako Katano, Nobutake Ozeki. Characteristics of MSCs in Synovial Fluid and Mode of Action of Intra-Articular Injections of Synovial MSCs in Knee Osteoarthritis. Int J Mol Sci. 2021.03; 22 (6): 2838. ( PubMed, DOI )

  53. Nobutake Ozeki, Yuji Kohno, Yoshihisa Kushida, Naoto Watanabe, Mitsuru Mizuno, Hisako Katano, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya. Synovial mesenchymal stem cells promote the meniscus repair in a novel pig meniscus injury model. J. Orthop. Res. 2021.01; 39 (1): 177-183. ( PubMed, DOI )

  54. Nobutake Ozeki, Romain Seil, Aaron J Krych, Hideyuki Koga. Surgical treatment of complex meniscus tear and disease: state of the art. J ISAKOS. 2021.01; 6 (1): 35-45. ( PubMed, DOI )

  55. Horiuchi Kiyotaka, Mizuno Mitsuru, Katano Hisako, Endo Kentaro, Ozeki Nobutake, Tsuji Kunikazu, Koga Hideyuki, Sekiya Ichiro.. Optimal initial cell density that yields the highest number of primary synovial mesenchymal stem cells in a clinical setting. J Med Dent Sci.. 2021.01; 68 17-26. ( DOI )

  56. Horiuchi Kiyotaka, Mizuno Mitsuru, Katano Hisako, Endo Kentaro, Ozeki Nobutake, Tsuji Kunikazu, Koga Hideyuki, Sekiya Ichiro. 臨床実地にて初代滑膜間葉系幹細胞の数が最大となるような最適な初期細胞密度(Optimal initial cell density that yields the highest number of primary synovial mesenchymal stem cells in a clinical setting) Journal of Medical and Dental Sciences. 2021; 68 17-26. ( ichushi )

  57. Yoshihisa Kushida, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Kunikazu Tsuji, Hideyuki Koga, Koichiro Kishima, Yoshio Soma, Ichiro Sekiya. Two- and three-dimensional optical coherence tomography to differentiate degenerative changes in a rat meniscectomy model. J Orthop Res. 2020.12; 38 (12): 2592-2600. ( PubMed, DOI )

  58. Watanabe N, Endo K, Komori K, Ozeki N, Mizuno M, Katano H, Kohno Y, Tsuji K, Koga H, Sekiya I. Mesenchymal Stem Cells in Synovial Fluid Increase in Knees with Degenerative Meniscus Injury after Arthroscopic Procedures through the Endogenous Effects of CGRP and HGF. Stem cell reviews and reports. 2020.12; 16 (6): 1305-1315. ( PubMed, DOI )

  59. Hideyuki Koga, Tomomasa Nakamura, Hiroki Katagiri, Yusuke Nakagawa, Nobutake Ozeki, Toshiyuki Ohara, Mikio Shioda, Yuji Kohno, Masaki Amemiya, Ichiro Sekiya. Two-Year Outcomes After Meniscoplasty by Capsular Advancement With the Application of Arthroscopic Centralization Technique for Lateral Compartment Knee Osteoarthritis. Am J Sports Med. 2020.11; 48 (13): 3154-3162. ( PubMed, DOI )

  60. Hayato Aoki, Nobutake Ozeki, Hisako Katano, Akinobu Hyodo, Yugo Miura, Junpei Matsuda, Kimiko Takanashi, Kenji Suzuki, Jun Masumoto, Noriya Okanouchi, Takeo Fujiwara, Ichiro Sekiya. Relationship between medial meniscus extrusion and cartilage measurements in the knee by fully automatic three-dimensional MRI analysis. BMC Musculoskelet Disord. 2020.11; 21 (1): 742. ( PubMed, DOI )

  61. So Suzuki, Mitsuru Mizuno, Yuriko Sakamaki, Ayako Mimata, Kentaro Endo, Yuji Kohno, Nobutake Ozeki, Koji Otabe, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya. Morphological changes in synovial mesenchymal stem cells during their adhesion to the meniscus. Lab. Invest.. 2020.07; 100 (7): 916-927. ( PubMed, DOI )

  62. Rei Kubota, Hideyuki Koga, Nobutake Ozeki, Junpei Matsuda, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Ichiro Sekiya. The effect of a centralization procedure for extruded lateral meniscus on load distribution in porcine knee joints at different flexion angles. BMC Musculoskelet Disord. 2020.04; 21 (1): 205. ( PubMed, DOI )

  63. Nobutake Ozeki, Hideyuki Koga, Junpei Matsuda, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Tomoyuki Saito, Takeshi Muneta, Ichiro Sekiya. Biomechanical analysis of the centralization procedure for extruded lateral menisci with posterior root deficiency in a porcine model. J Orthop Sci.. 2020.01; 25 (1): 161-166. ( PubMed, DOI )

  64. Mitsuru Mizuno, Hisako Katano, Yuri Shimozaki, Sho Sanami, Nobutake Ozeki, Hideyuki Koga, Ichiro Sekiya. Time-lapse image analysis for whole colony growth curves and daily distribution of the cell number per colony during the expansion of mesenchymal stem cells. Sci Rep. 2019.11; 9 (1): 16835. ( PubMed, DOI )

  65. Ichiro Sekiya, Hideyuki Koga, Koji Otabe, Yusuke Nakagawa, Hisako Katano, Nobutake Ozeki, Mitsuru Mizuno, Masafumi Horie, Yuji Kohno, Kenta Katagiri, Naoto Watanabe, Takeshi Muneta. Additional Use of Synovial Mesenchymal Stem Cell Transplantation Following Surgical Repair of a Complex Degenerative Tear of the Medial Meniscus of the Knee: A Case Report. Cell Transplant. 2019.11; 28 (11): 1445-1454. ( PubMed, DOI )

  66. Naoto Watanabe, Mitsuru Mizuno, Junpei Matsuda, Naoko Nakamura, Koji Otabe, Hisako Katano, Nobutake Ozeki, Yuji Kohno, Tsuyoshi Kimura, Kunikazu Tsuji, Hideyuki Koga, Akio Kishida, Ichiro Sekiya. Comparison of High-Hydrostatic-Pressure Decellularized Versus Freeze-Thawed Porcine Menisci. J. Orthop. Res.. 2019.11; 37 (11): 2466-2475. ( PubMed, DOI )

  67. Akinobu Hyodo, Nobutake Ozeki, Yuji Kohno, So Suzuki, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Makoto Tomita, Yusuke Nakagawa, Hideyuki Koga, Shinji Kiuchi, Kenji Suzuki, Yoshinori Itai, Jun Masumoto, Ichiro Sekiya. Projected Cartilage Area Ratio Determined by 3-Dimensional MRI Analysis: Validation of a Novel Technique to Evaluate Articular Cartilage. JB JS Open Access. 2019.10; 4 (4): e0010. ( PubMed, DOI )

  68. Ryota Fujisawa, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Nobutake Ozeki, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya. Cryopreservation in 95% serum with 5% DMSO maintains colony formation and chondrogenic abilities in human synovial mesenchymal stem cells. BMC Musculoskelet Disord. 2019.07; 20 (1): 316. ( PubMed, DOI )

  69. Naritomi M, Mizuno M, Katano H, Ozeki N, Otabe K, Komori K, Fujii S, Ichinose S, Tsuji K, Koga H, Muneta T, Sekiya I. Petaloid recombinant peptide enhances in vitro cartilage formation by synovial mesenchymal stem cells. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2019.06; 37 (6): 1350-1357. ( PubMed, DOI )

  70. Akari Sasaki, Mitsuru Mizuno, Nobutake Ozeki, Hisako Katano, Koji Otabe, Kunikazu Tsuji, Hideyuki Koga, Manabu Mochizuki, Ichiro Sekiya. Canine mesenchymal stem cells from synovium have a higher chondrogenic potential than those from infrapatellar fat pad, adipose tissue, and bone marrow. PLoS ONE. 2018.08; 13 (8): e0202922. ( PubMed, DOI )

  71. Katano H, Koga H, Ozeki N, Otabe K, Mizuno M, Tomita M, Muneta T, Sekiya I.. Trends in isolated meniscus repair and meniscectomy in Japan, 2011-2016. PLoS ONE. 2018.07; 23 (4): 676-681. ( PubMed, DOI, ichushi )

  72. Mitsuru Mizuno, Hisako Katano, Yo Mabuchi, Yusuke Ogata, Shizuko Ichinose, Shizuka Fujii, Koji Otabe, Keiichiro Komori, Nobutake Ozeki, Hideyuki Koga, Kunikazu Tsuji, Chihiro Akazawa, Takeshi Muneta, Ichiro Sekiya. Specific markers and properties of synovial mesenchymal stem cells in the surface, stromal, and perivascular regions. Stem Cell Res Ther. 2018.05; 9 (1): 123. ( PubMed, DOI )

  73. Yuji Kohno, Mitsuru Mizuno, Nobutake Ozeki, Hisako Katano, Koji Otabe, Hideyuki Koga, Mikio Matsumoto, Haruka Kaneko, Yuji Takazawa, Ichiro Sekiya. Comparison of mesenchymal stem cells obtained by suspended culture of synovium from patients with rheumatoid arthritis and osteoarthritis. BMC Musculoskelet Disord. 2018.03; 19 (1): 78. ( PubMed, DOI )

  74. Mitsuru Mizuno, Hisako Katano, Koji Otabe, Keiichiro Komori, Yuji Kohno, Shizuka Fujii, Nobutake Ozeki, Masafumi Horie, Kunikazu Tsuji, Hideyuki Koga, Takeshi Muneta, Ichiro Sekiya. Complete human serum maintains viability and chondrogenic potential of human synovial stem cells: suitable conditions for transplantation. Stem Cell Res Ther. 2017.06; 8 (1): 144. ( PubMed, DOI )

  75. Yuji Kohno, Mitsuru Mizuno, Nobutake Ozeki, Hisako Katano, Keiichiro Komori, Shizuka Fujii, Koji Otabe, Masafumi Horie, Hideyuki Koga, Kunikazu Tsuji, Mikio Matsumoto, Haruka Kaneko, Yuji Takazawa, Takeshi Muneta, Ichiro Sekiya. Yields and chondrogenic potential of primary synovial mesenchymal stem cells are comparable between rheumatoid arthritis and osteoarthritis patients. Stem Cell Res Ther. 2017.05; 8 (1): 115. ( PubMed, DOI )

  76. Nobutake Ozeki, Takeshi Muneta, Kenichi Kawabata, Hideyuki Koga, Yusuke Nakagawa, Ryusuke Saito, Mio Udo, Katsuaki Yanagisawa, Toshiyuki Ohara, Tomoyuki Mochizuki, Kunikazu Tsuji, Tomoyuki Saito, Ichiro Sekiya. Centralization of extruded medial meniscus delays cartilage degeneration in rats. J Orthop Sci. 2017.05; 22 (3): 542-548. ( PubMed, DOI, ichushi )

  77. Katagiri Kenta, Yu Matsukura, Takeshi Muneta, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Ichiro Sekiya.. Fibrous synovium releases higher numbers of mesenchymal stem cells than adipose synovium in a suspended synovium culture model. Arthroscopy. 2017.04; 33 (4): 800-810. ( PubMed )

  78. Saito R, Muneta T, Ozeki N, Nakagawa Y, Udo M, Yanagisawa K, Tsuji K, Tomita M, Koga H, Sekiya I.. Strenuous running exacerbates knee cartilage erosion induced by low amount of mono-iodoacetate in rats. BMC Musculoskelet Disord. 2017.01; 18 (1): 36.

  79. Saito Ryusuke, Muneta Takeshi, Ozeki Nobutake, Nakagawa Yusuke, Udo Mio, Yanagisawa Katsuaki, Tsuji Kunikazu, Tomita Makoto, Koga Hideyuki, Sekiya Ichiro. Strenuous running exacerbates knee cartilage erosion induced by low amount of mono-iodoacetate in rats BMC MUSCULOSKELETAL DISORDERS. 2017.01; 18 (1): 36. ( PubMed, DOI )

  80. N Ozeki, T Muneta, H Koga, Y Nakagawa, M Mizuno, K Tsuji, Y Mabuchi, C Akazawa, E Kobayashi, K Matsumoto, K Futamura, T Saito, I Sekiya. Not single but periodic injections of synovial mesenchymal stem cells maintain viable cells in knees and inhibit osteoarthritis progression in rats. Osteoarthritis Cartilage. 2016.06; 24 (6): 1061-1070. ( PubMed, DOI )

  81. Mitsuru Mizuno, Hisako Katano, Koji Otabe, Keiichiro Komori, Yukie Matsumoto, Shizuka Fujii, Nobutake Ozeki, Kunikazu Tsuji, Hideyuki Koga, Takeshi Muneta, Akifumi Matsuyama, Ichiro Sekiya. Platelet-derived growth factor (PDGF)-AA/AB in human serum are potential indicators of the proliferative capacity of human synovial mesenchymal stem cells. Stem Cell Res Ther. 2015.12; 6 243. ( PubMed, DOI )

  82. Nobutake Ozeki, Takeshi Muneta, Seiya Matsuta, Hideyuki Koga, Yusuke Nakagawa, Mitsuru Mizuno, Kunikazu Tsuji, Yo Mabuchi, Chihiro Akazawa, Eiji Kobayashi, Tomoyuki Saito, Ichiro Sekiya. Synovial mesenchymal stem cells promote meniscus regeneration augmented by an autologous Achilles tendon graft in a rat partial meniscus defect model. Stem Cells. 2015.06; 33 (6): 1927-1938. ( PubMed, DOI )

  83. Suto EG, Mabuchi Y, Suzuki N, Koyanagi A, Kawabata Y, Ogata Y, Ozeki N, Nakagawa Y, Muneta T, Sekiya I, Akazawa C. High capacity of puri ed mesenchymal stem cells for cartilage regeneration  Inflammation and Regeneration. 2015.03; 35 (2): 78-85. ( DOI )

  84. Makiko Okuno, Takeshi Muneta, Hideyuki Koga, Nobutake Ozeki, Yusuke Nakagawa, Kunikazu Tsuji, Shinichi Yoshiya, Ichiro Sekiya. Meniscus Regeneration by Syngeneic, Minor Mismatched, and Major Mismatched Transplantation of Synovial Mesenchymal Stem Cells in a Rat Model  JOURNAL OF ORTHOPAEDIC RESEARCH. 2014.07; 32 (7): 928-936. ( DOI )

  85. Ozeki N, Muneta T, Koga H, Katagiri H, Otabe K, Okuno M, Tsuji K, Kobayashi E, Matsumoto K, Saito H, Saito T, Sekiya I. Transplantation of achilles tendon treated with bone morphogenetic protein 7 promotes meniscus regeneration in a rat model of massive meniscal defect  Arthritis and Rheumatism . 2013.07; 65 (11): 2876-2886. ( DOI )

  86. Hiroki Katagiri, Takeshi Muneta, Kunikazu Tsuji, Masafumi Horie, Hideyuki Koga, Nobutake Ozeki, Eiji Kobayashi, Ichiro Sekiya. Transplantation of aggregates of synovial mesenchymal stem cells regenerates meniscus more effectively in a rat massive meniscal defect  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS . 2013.06; 435 (4): 603-609. ( DOI )

  87. Nobutake Ozeki, Yoichi Aota, Masaaki Uesugi, Kanichiro Kaneko, Hisanori Mihara, Takanori Niimura, Tomoyuki Saito. Clinical results of intrapedicular partial pediculectomy for lumbar foraminal stenosis. J Spinal Disord Tech. 2008.07; 21 (5): 324-327. ( PubMed, DOI )

▼display all

Conference Activities & Talks 【 display / non-display

  1. Nobutake Ozeki. The association of the medial meniscus covering ratio with knee cartilage thickness by 3D MRI. IWOAI 2024 2024.06.25 Morocco

  2. Nobutake Ozeki, Tomomasa Nakamura, Yusuke Nakagawa, Takashi Hoshino, Masaki Amemiya, Aritoshi Yoshihara, Ichiro Sekiya, Hideyuki Koga. Reduction of medial meniscus extrusion by centralization with medial meniscus root tear repair.. 21st ESSKA Congress 2024.05.08 Milano, Italy

  3. Nobutake,Ozeki. Current treatment using stem cell-based meniscus treatment. 1st The Asian Meniscus Summit 2023.10.05

  4. Nakagawa Yusuke, Ozeki Nobutake, Koga Hideyuki, Sekiya Ichiro. 変形性膝関節症に対する滑膜MSCを用いた幹細胞療法(Stem cell therapy using synovial MSCs for knee osteoarthritis). 日本整形外科学会雑誌 2023.03.01

  5. Nobutake Ozeki. IS THERE A ROLE FOR MRI IN REGENERATIVE MEDICINE?. 16th International Workshop on Osteoarthritis Imaging 2022.07.07 Tokyo

  6. Sekiya Ichiro, Katano Hisako, Koga Hideyuki, Tomita Makoto, Suzuki Kenji, Masumoto Jun, Okawa Atsushi, Ozeki Nobutake. 変形性膝関節症における内側半月板内縁からの軟骨欠損(Cartilage defects extend from the medial margin of medial meniscus in knee osteoarthritis). 日本整形外科学会雑誌 2022.03.01

  7. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Yusuke Nakagawa, Hiroki Katagiri, Hisako Katano, Makoto Tomita, Jun Masumoto, Ichiro Sekiya. Relationship Between Cartilage Thickness By 3D MRI Analysis And ICRS Arthroscopic Grade In The Knee Joint. Orthopaedic Research Society 2022 Annual Meeting 2022.02.05 Tampa,USA

  8. Nobutake Ozeki, Hiroki Katagiri, Yusuke Nakagawa , Toshiyuki Ohara, Mikio Shioda, Yuji Kohno, Masaki Amemiya, Ichiro Sekiya, Hideyuki Koga.. Ramp lesions in anterior cruciate ligament deficient knees.. 2nd International Knee Day 2021.03.18 WEB

  9. Nobutake Ozeki, Hideyuki Koga,Tomomasa Nakamura,Yusuke Nakagawa, Yuji Kohno, Hisako Katano, Kenji Suzuki, Jun Masumoto, Ichiro Sekiya.. 3D MRI Analysis For Cartilage In Anterior Cruciate Ligament Deficient Knees Using Radially Projected Images.. Orthopaedic Research Society 2021 Annual Meeting 2021.02.12 California,USA

  10. Yugo Miura, Nobutake Ozeki, Yuji Kohno, Hisako Katano, Hayato Aoki, Noriya Okanouchi, Makoto Tomita, Kenji Suzuki, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya.. Difference In The Joint Space Of The Medial Knee Compartment Between Full Extension And Rosenberg Weight-bearing Radiographs.. Orthopaedic Research Society 2021 Annual Meeting 2021.02.12 California,USA

  11. Yoshihisa Kushida, Nobutake Ozeki, Hisako Katano, Mitsuru Mizuno, Ichiro Sekiya.. 2D And 3D Optical Coherence Tomography To Differentiate Degenerative Changes In A Rat Meniscectomy Model.. Orthopaedic Research Society 2020 Annual Meeting 2020.02.11 Phoenix,USA

  12. Akinobu Hyodo. Nobutake Ozeki, Hayato Aoki, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Kenji Suzuki, Jun Masumoto, Ichiro Sekiya.. Radial Projected Femoral Cartilage Area By Automatic Cartilage Segmentation For The Knee MRI.. Orthopaedic Research Society 2020 Annual Meeting 2020.02.11 Phoenix,USA

  13. So Suzuki, Mitsuru Mizuno, Yuji Kohno, Nobutake Ozeki, Koji Otabe, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.. Quantitative Morphological Analysis Of Synovial Mesenchymal Stem Cells During Adhesion To The Meniscus.. Orthopaedic Research Society 2020 Annual Meeting 2020.02.10 Phoenix,USA

  14. Hayato Aoki, Nobutake Ozeki, Akinobu Hyodo, Yuji Kohno, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Kenji Suzuki, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya.. Learning Times And Segmentation Accuracy Of U-net Convolutional Neural Networks On Automatic Segmentation For Mri Of Knee.. Orthopaedic Research Society 2020 Annual Meeting 2020.02.09 Phoenix,USA

  15. Rei Kubota, Hideyuki Koga, Nobutake Ozeki, Yuji Kohno, Junpei Matsuda, Yoshihisa Kushida, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Ichiro Sekiya.. The Effect Of Centralization Procedure For Extruded Lateral Meniscus On Load Distributionin Porcine Knee Joints At 30-90 Degrees Of Flexion.. Orthopaedic Research Society 2020 Annual Meeting 2020.02.08 Phoenix,USA

  16. Kiyotaka Horiuchi, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Keiichiro Komori, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.. Comparison Between Cultured Mscs And Non-cultured Mscs After Cryopreservation For Intra-articular Injections Into The Knee In A Rat Oa Model.. Orthopaedic Research Society 2020 Annual Meeting 2020.02.08 Phoenix,USA

  17. Nobutake Ozeki, Hideyuki Koga, Hayato Aoki, Akinobu Hyodo, Hiroki Katagiri, Yusuke Nakagawa, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Kenji Suzuki, Jun Masumoto, Ichiro Sekiya.. 3D MRI Analysis For Cartilage In Anterior Cruciate Ligament Deficient Knee.. Orthopaedic Research Society 2020 Annual Meeting 2020.02.08 Phoenix,USA

  18. Nobutake Ozeki, Hideyuki Koga, Hayato Aoki, Akinobu Hyodo, Kenji Suzuki, Yoshinori Itai, Jun Masumoto, Ichiro Sekiya. . 3D MRI analysis for cartilage in anterior cruciate ligament injured knees.. 13th International Workshop on Osteoarthritis Imaging 2019.06.26 Charlottetown, Canada

  19. Hayato Aoki, Nobutake Ozeki, Akinobu Hyodo, Kenji Suzuki, Yoshinori Itai, Jun Masumoto, Ichiro Sekiya.. Learning times and segmentation accuracy of U-Net Convolutional Neural Networks on automatic segmentation for MRI of knee.. 13th International Workshop on Osteoarthritis Imaging 2019.06.26 Charlottetown, Canada

  20. Akinobu Hyodo,Nobutake Ozeki, Yuji Kohno, So Suzuki, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Makoto Tomita, Yusuke Nakagawa, Hideyuki Koga, Shinji Kiuchi, Kenji Suzuki, Yoshinori Itai, Jun Masumoto, Ichiro Sekiya.. Projected cartilage area ratio determined by 3D MRI analysis: a validation of a novel technique to evaluate articular cartilage.. 13th International Workshop on Osteoarthritis Imaging 2019.06.26 Charlottetown, Canada

  21. Mitsuru Mizuno, Hisako Katano, Yuri Shimozaki, Sho Sanami, Koji Otabe, Nobutake Ozeki, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.. Time Lapse Imaging Analysis On Colony Proliferation Process Of Primary Synovial Mscs.. Orthopaedic Research Society 2019 Annual Meeting 2019.02.05 Austin,USA

  22. So Suzuki, Mitsuru Mizuno, Yoshihisa Kushida, Yuji Kohno, Nobutake Ozeki, Koji Otabe, Shizuko Ichinose, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.. Morphological Alterations Of Synovial Mesenchymal Stem Cells During Adhesion To The Meniscus.. Orthopaedic Research Society 2019 Annual Meeting 2019.02.05 Austin,USA

  23. Yoshihisa Kushida, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.. Quantification Of Cartilage Volume By 3D Color Optical Coherence Tomography In A Meniscectomized Rat Model.. Orthopaedic Research Society 2019 Annual Meeting 2019.02.05 Austin,USA

  24. Yoshihisa Kushida, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.. Use Of 3D MRI And 3D T2 Mapping Images For Evaluation Of The Natural Course Of Cartilage Repair In The Knees Of Micromini Pigs.. Orthopaedic Research Society 2019 Annual Meeting 2019.02.05 Austin,USA

  25. Yuji Kohno, Mitsuru Mizuno, Otabe Koji, Nobutake Ozeki, Hisako Katano, Keiichiro Komori, Kunikazu Tsuji, Mikio Matsumoto, Haruka Kaneko, Yuji Takazawa, Hideyuki Kog, Ichiro Sekiya.. Yields Of MSCs From Synovial Fluid Reflect Yields Of MSCs From The Synovium Of RA Knees.. Orthopaedic Research Society 2019 Annual Meeting 2019.02.05 Austin,USA

  26. Naoto Watanabe, Nobutake Ozeki, Mitsuru Mizuno, Keiichiro Komori, Yuji Kohno, Hisako Katano, Koji Otabe, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.. Quantitative Analysis Of Mesenchymal Stem Cells (MSCs) In Synovial Fluid Two Weeks After Synovial Removal And Meniscus Repair, Followed By Transplantation Of Synovial MSCs.. Orthopaedic Research Society 2019 Annual Meeting 2019.02.05 Austin,USA

  27. Naoto Watanabe, Mitsuru Mizuno, Junpei Matsuda, Naoko Nakamura, Koji Otabe, Hisako Katano, Nobutake Ozeki, Yuji Kohno, Tsuyoshi Kimura, Kunikazu Tsuji, Hideyuki Koga, Akio Kishida, Ichiro Sekiya.. Comparison Of Decellularized Meniscus By High Hydrostatic Pressure With Freeze-thawed Meniscus.. Orthopaedic Research Society 2019 Annual Meeting 2019.02.05 Austin,USA

  28. So Suzuki, Nobutake Ozeki, Yuji Kohno, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Kunikazu Tsuji, Keniji Suzuki, Yoshinori Itai, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya.. Medial Meniscus Extrusion (MME) Area And MME Volume Determined By 3D-MRI Are More Sensitive Than Mme Distance Determined By 2D-MRI For Evaluating Cartilage Loss In Knees With Medial Meniscus Degenerative Tears.. Orthopaedic Research Society 2019 Annual Meeting 2019.02.03 Austin,USA

  29. Hayato Aoki, Nobutake Ozeki, Akinobu Hyodo, So Suzuki, Yoshihisa Kushida, Naoto Watanabe, Yuji Kohno, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Kunikazu Tsuji, Kenji Suzuki, Yoshinori Itai, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya.. Whole Image Of Discoid Lateral Meniscus Analyzed By 3d Mri.. Orthopaedic Research Society 2019 Annual Meeting 2019.02.03 Austin,USA

  30. Kiyotaka Horiuchi, Hideyuki Koga, Mitsuru Mizuno, Hisako Katano, Keiichiro Komori, Koji Otabe, Shizuka Fujii, Nobutake Ozeki, Tsujii Kunikazu, Ichiro Sekiya.. Determining The Optimum Initial Cell Density That Yields The Highest Number Of Mesenchymal Stem Cells Per Dish.. Orthopaedic Research Society 2019 Annual Meeting 2019.02.03 Austin,USA

  31. Ryota Fujisawa, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Keiichiro Komori, Shizuka Fujii, Nobutake Ozeki, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.. Cryopreservation In 95% Serum With 5% Dmso Maintained Colony Formation And Chondrogenic Abilities In Human Synovial Mesenchymal Stem Cells.. Orthopaedic Research Society 2019 Annual Meeting 2019.02.03 Austin,USA

  32. Rei Kubota, Hideyuki Koga, Nobutake Ozeki, Yuji Kohno, Junpei Matsuda, Yoshihisa Kushida, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Ichiro Sekiya.. Influence Of Knee Flexion Angle On The Biomechanical Effect Of Centralization For Extruded Lateral Meniscus. Orthopaedic Research Society 2019 Annual Meeting 2019.02.02 Austin,USA

  33. Akinobu Hyodo, Nobutake Ozeki, So Suzuki, Hayato Aoki, Naoto Watanabe, Yoshihisa Kushida, Yuji Kohno, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Kunikazu Tsuji, Kenji Suzuki, Yoshinori Itai, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya.. “Projected Cartilage Area Ratio” By Mri 3d Analysis Detects Decrease Of Cartilage Amount In Several Months In Patients Complaining Knee Pain.. Orthopaedic Research Society 2019 Annual Meeting 2019.02.02 Austin,USA

  34. Sekiya Ichiro, Koga Hideyuki, Otabe Koji, Nakagawa Yusuke, Katano Hisako, Ozeki Nobutake, Mizuno Mitsuru, Horie Masafumi, Muneta Takeshi. Regenerative medicine in Knee 変性半月板断裂に対する修復+滑膜幹細胞移植の2年成績(Regenerative medicine in Knee Transplantation of synovial stem cells onto degenerative torn meniscus: a 2-year follow-up study). JOSKAS 2018.05.01

  35. Ochi Miharu, Ozeki Nobutake, Muneta Takeshi, Koga Hideyuki, Sekiya Ichiro. 滑膜幹細胞およびBMP2による腱の軟骨形成(Cartilage formation of tendon with synovial stem cells and BMP2). JOSKAS 2018.05.01

  36. Yoshihisa Kushida, Koichiro Kishima Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.. Pseudo Color Images and Volume Measurement of Cartilage by Optical Coherence Tomography in a Rat Meniscectomized Model.. Orthopaedic Research Society 2018 Annual Meeting 2018.03.12 New Orleans, USA

  37. Hayato Aoki, Nobutake Ozeki, Kohno yuji, Kushida Yoshihisa, Naoto Watanabe, Akinobu Hyodo, So Suzuki, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Kunikazu Tsuji, Yoshinori Itai, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya.. Mri 3d Analysis For Discoid Lateral Meniscus Of The Knee.. Orthopaedic Research Society 2018 Annual Meeting 2018.03.12 New Orleans, USA

  38. Mitsuru Mizuno, Hisako Katano, Yuri Shimozaki, Sho Sanami, Keiichiro Komori, Koji Otabe, Nobutake Ozeki, Kunikazu Tsuji, Koga Hideyuki, Ichiro Sekiya.. Image Analysis Method to Predict Cell Proliferation at Early Phase for Autologous Synovial Stem Cell Transplantation.. Orthopaedic Research Society 2018 Annual Meeting 2018.03.12 New Orleans, USA

  39. Naoto Watanabe, Mitsuru Mizuno, Jumpei Matsuda, Naoko Nakamura, Koji Otabe, Hisako Katano, Nobutake Ozeki, Yuji Kono, Tsuyoshi Kimura, Kunikazu Tsuji, Hideyuki Koga, Akio Kishida, Ichiro Sekiya. Can Decellularized Meniscus by High Hydrostatic Pressure be an Alternative to Meniscus Allograft? - Compared with Deep Frozen Meniscus.. Orthopaedic Research Society 2018 Annual Meeting 2018.03.12 New Orleans, USA

  40. Miharu Ochi, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.. Effects of synovial stem cells and BMP-2 on cartilage formation of tendon.. Orthopaedic Research Society 2018 Annual Meeting 2018.03.11 New Orleans, USA

  41. Ryota Fujisawa, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Keiichiro Komori, Shizuka Fujii, Nobutake Ozeki, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.. Investigation of Freezing Medium for Synovial Mesenchymal Stem Cells.. Orthopaedic Research Society 2018 Annual Meeting 2018.03.11 New Orleans, USA

  42. Mana Naritomi, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Keiichiro Komori, Shizuka Fujii, Shizuko Ichinose, Nobutake Ozeki, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.. Petaloid Recombinant Peptide Constructs the Framework of Cartilage Pellet and Promotes In Vitro Cartilage Formation.. Orthopaedic Research Society 2018 Annual Meeting 2018.03.11 New Orleans, USA

  43. Yuji Kohno, Hideyuki Koga, Nobutake Ozeki, Junpei Matsuda, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Kunikazu Tsuji, Ichiro Sekiya. Biomechanical analysis of meniscus centralization for extruded meniscus after meniscectomy. Orthopaedic Research Society 2018 Annual Meeting 2018.03.11

  44. Yuji Kohno, Nobutake Ozeki, Akinobu Hyodo, So Suzuki, Hayato Aoki, Yoshihisa Kushida, Naoto Watanabe, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Kunikazu Tsuji, Yoshinori Itai, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya. Validations for cartilage thickness, cartilage area ratio and meniscus volume in the knee by 3D MRI analysis. Orthopaedic Research Society 2018 Annual Meeting 2018.03.11 New Orleans

  45. Nobutake Ozeki, Yuji Kohno, Yoshihisa Kushida, Naoto Watanabe, Kenta Katagiri, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Kunikazu Tsuji, Yoshinori Itai, Jun Masumoto, Hideyuki Koga, Tomoyuki Saito, Ichiro Sekiya. Three-Dimensional MRI, T2 Mapping and Histological Analyses of Meniscus Repair After Transplantation of Synovial Mesenchymal Stem Cells in a Novel Degenerative Meniscus Injury Model in Pig . Orthopaedic Research Society 2018 Annual Meeting 2018.03.11 New Orleans, USA

  46. So Suzuki, Nobutake Ozeki, Akinobu Hyodo, Hayato Aoki, Yoshihisa Kushida, Naoto Watanabe, Yuji Kohno, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Kunikazu Tsuji, Yoshinori Itai, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya.. "Cartilage Area Ratio"by MRI 3D Analysis Reveals Subtle Change of Cartilage Volume in Middle Aged Patients with Medeal Meniscus Degenerative Tear.. Orthopaedic Research Society 2018 Annual Meeting 2018.03.11 New Orleans, USA

  47. Kenta Katagiri, Mitsuru Mizuno, Hideyuki Koga, Nobutake Ozeki, Yusuke Nakagawa, Yuji Kono, Koji Otabe, Masafumi Horie, Hisako Katano,Kunikazu Tsuji, Hideo Ono, Takeshi Muneta, Ichiro Sekiya.. Transplantation of Synovial Mesenchymal Stem Cells Enhances the Effect of Cetralization with Suture Anchor and Promotes Meniscus Regeneration for Extruded Meniscus After Partial Meniscectomy in Microminipigs. Orthopaedic Research Society 2017 Annual Meeting 2017.03.22 SanDiego, USA

  48. Yuji Kono, Mitsuru Mizuno, Kenta Katagiri, Koji Otabe, Nobutake Ozeki, Hisako Katao, Keiichiro Komori, Masafuji Horie, Kunikazu Tsuji, Mikio Matsumoto, Haruka Kaeko, Yuji Takazawa, Takeshi Muneta, Ichiro Sekiya.. Harvested cell number varies greater in RA than in OA after a suspended synovium culture. Orthopaedic Research Society 2017 Annual Meeting 2017.03.22 SanDiego, USA

  49. Mitsuru Mizuno, Hisako Katano, Koji Otabe, Keiichiro Komori, Yuji Kohno, Shizuka Fujii, Nobutake Ozeki, Masafumi Horie, Kunikazu Tsuji, Takeshi Muneta, Ichiro Sekiya.. Complete Human Serum Maintains Viability and Chondrogenic Potential of Human Synovial Stem Cells: Suitable Condition for Transplantation. Orthopaedic Research Society 2017 Annual Meeting 2017.03.21 SanDiego, USA

  50. Naoto Watanabe, Mitsuru Mizuno, Jumpei Matsuda, Hisako Katano, Nobutake Ozeki, Koji Otabe, Keiichiro Komori, Yuji Kono, Kenta Katagiri, Takeshi Muneta, Ichiro Sekiya.. Decellularization of the meniscus by high hydrostatic pressure: temperature condition for removal of cell debris.. Orthopaedic Research Society 2017 Annual Meeting 2017.03.20 SanDiego, USA

  51. Mana Naritomi, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Keiichiro Komori, Shizuka Fujii, Nobutake Ozeki, Masafumi Horie, Kunikazu Tsuji, Takeshi Muneta, Ichiro Sekiya.. Recombinant peptide petaloid pieces enhance in vitro cartilage formation of mesenchymal stem cells. Orthopaedic Research Society 2017 Annual Meeting 2017.03.20 SanDiego, USA

  52. M . Uomizu, T. Mochizuki, T. Ohara, J. Matsuda, N. Ozeki, K. Tsuji, A. Nimura, T. Miyamoto, M. Goto, I. Sekiya, T. Muneta . Synovium-derived MSCs promote the restoration of tensile strength of the rotator cuff tendon after repair in a rat model. Orthopaedic Research Society 2017 Annual Meeting 2017.03.19 San Diego, CA, USA

  53. Ozeki N, Sekiya I, Saito T, Muneta T. Transplantation of Achilles tendon treated with BMP-7 promoted meniscus regeneration in a rat massive meniscus defect model. 11th World Congress of the international cartilage repair society 2012.05.12 Montreal, Canada

  54. Ozeki N, Sekiya I, Saito T, Muneta T. Transplantation of Achilles tendon treated with BMP-7 promoted meniscus regeneration in a rat massive meniscus defect model. World Congress on Osteoarthritis 2012.04.26 Barcerona, Spain

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