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Takagi M, Hoshino A, Bousset K, Röddecke J, Martin HL, Folcut I, Tomomasa D, Yang X, Kobayashi J, Sakata N, Yoshida K, Miyano S, Ogawa S, Kojima S, Morio T, Dörk T, Kanegane H. Bone Marrow Failure and Immunodeficiency Associated with Human RAD50 Variants. Journal of clinical immunology. 2023.11; 43 (8): 2136-2145. ( PubMed, DOI )

Kusumoto T, Chubachi S, Namkoong H, Tanaka H, Lee H, Azekawa S, Otake S, Nakagawara K, Fukushima T, Morita A, Watase M, Sakurai K, Asakura T, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Edahiro R, Sano H, Sato Y, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Association between ABO blood group/genotype and COVID-19 in a Japanese population. Annals of hematology. 2023.11; 102 (11): 3239-3249. ( PubMed, DOI )

Tanaka H, Maetani T, Chubachi S, Tanabe N, Shiraishi Y, Asakura T, Namkoong H, Shimada T, Azekawa S, Otake S, Nakagawara K, Fukushima T, Watase M, Terai H, Sasaki M, Ueda S, Kato Y, Harada N, Suzuki S, Yoshida S, Tateno H, Yamada Y, Jinzaki M, Hirai T, Okada Y, Koike R, Ishii M, Hasegawa N, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Clinical utilization of artificial intelligence-based COVID-19 pneumonia quantification using chest computed tomography - a multicenter retrospective cohort study in Japan. Respiratory research. 2023.10; 24 (1): 241. ( PubMed, DOI )

Tanaka H, Namkoong H, Chubachi S, Irie S, Uwamino Y, Lee H, Azekawa S, Otake S, Nakagawara K, Fukushima T, Watase M, Kusumoto T, Masaki K, Kamata H, Ishii M, Okada Y, Takano T, Imoto S, Koike R, Kimura A, Miyano S, Ogawa S, Kanai T, Sato TA, Fukunaga K, Japan COVID-19 Task Force. Clinical characteristics of patients with COVID-19 harboring detectable intracellular SARS-CoV-2 RNA in peripheral blood cells. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2023.10; 135 41-44. ( PubMed, DOI )

Suzuki M, Kasajima R, Yokose T, Shimizu E, Hatakeyama S, Yamaguchi K, Yokoyama K, Katayama K, Yamaguchi R, Furukawa Y, Miyano S, Imoto S, Shinozaki-Ushiku A, Ushiku T, Miyagi Y. KMT2C expression and DNA homologous recombination repair factors in lung cancers with a high-grade fetal adenocarcinoma component. Translational lung cancer research. 2023.08; 12 (8): 1738-1751. ( PubMed, DOI )

Nishimura T, Kakiuchi N, Yoshida K, Sakurai T, Kataoka TR, Kondoh E, Chigusa Y, Kawai M, Sawada M, Inoue T, Takeuchi Y, Maeda H, Baba S, Shiozawa Y, Saiki R, Nakagawa MM, Nannya Y, Ochi Y, Hirano T, Nakagawa T, Inagaki-Kawata Y, Aoki K, Hirata M, Nanki K, Matano M, Saito M, Suzuki E, Takada M, Kawashima M, Kawaguchi K, Chiba K, Shiraishi Y, Takita J, Miyano S, Mandai M, Sato T, Takeuchi K, Haga H, Toi M, Ogawa S. Evolutionary histories of breast cancer and related clones. Nature. 2023.08; 620 (7974): 607-614. ( PubMed, DOI )

Tanaka H, Chubachi S, Namkoong H, Sato Y, Asakura T, Lee H, Azekawa S, Otake S, Nakagawara K, Fukushima T, Watase M, Sakurai K, Kusumoto T, Kondo Y, Masaki K, Kamata H, Ishii M, Kaneko Y, Hasegawa N, Ueda S, Sasaki M, Izumo T, Inomata M, Miyazawa N, Kimura Y, Suzuki Y, Harada N, Ichikawa M, Takata T, Ishikura H, Yoshiyama T, Kokuto H, Murakami K, Sano H, Ueda T, Kuwahara N, Fujiwara A, Ogura T, Inoue T, Asami T, Mutoh Y, Nakachi I, Baba R, Nishi K, Tani M, Kagyo J, Hashiguchi M, Oguma T, Asano K, Nishikawa M, Watanabe H, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Propensity-Score Matched Analysis of the Effectiveness of Baricitinib in Patients With Coronavirus Disease 2019 (COVID-19) Using Nationwide Real-World Data: An Observational Matched Cohort Study From the Japan COVID-19 Task Force. Open forum infectious diseases. 2023.07; 10 (7): ofad311. ( PubMed, DOI )

Tanaka H, Chubachi S, Asakura T, Namkoong H, Azekawa S, Otake S, Nakagawara K, Fukushima T, Lee H, Watase M, Sakurai K, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Characteristics and clinical effectiveness of COVID-19 vaccination in hospitalized patients in Omicron-dominated epidemic wave - a nationwide study in Japan. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2023.07; 132 84-88. ( PubMed, DOI )

Hara Y, Shiba N, Yoshida K, Yamato G, Kaburagi T, Shiraishi Y, Ohki K, Shiozawa Y, Kawamura M, Kawasaki H, Sotomatsu M, Takizawa T, Matsuo H, Shimada A, Kiyokawa N, Tomizawa D, Taga T, Ito E, Horibe K, Miyano S, Adachi S, Taki T, Ogawa S, Hayashi Y. TP53 and RB1 alterations characterize poor prognostic subgroups in pediatric acute myeloid leukemia. Genes, chromosomes & cancer. 2023.07; 62 (7): 412-422. ( PubMed, DOI )

Ozawa T, Asakura T, Chubachi S, Namkoong H, Tanaka H, Lee K, Fukushima T, Otake S, Nakagawara K, Watase M, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Edahiro R, Murakami K, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force. Use of the neutrophil-to-lymphocyte ratio and an oxygen requirement to predict disease severity in patients with COVID-19. Respiratory investigation. 2023.07; 61 (4): 454-459. ( PubMed, DOI )

Kitagawa A, Osawa T, Noda M, Kobayashi Y, Aki S, Nakano Y, Saito T, Shimizu D, Komatsu H, Sugaya M, Takahashi J, Kosai K, Takao S, Motomura Y, Sato K, Hu Q, Fujii A, Wakiyama H, Tobo T, Uchida H, Sugimachi K, Shibata K, Utsunomiya T, Kobayashi S, Ishii H, Hasegawa T, Masuda T, Matsui Y, Niida A, Soga T, Suzuki Y, Miyano S, Aburatani H, Doki Y, Eguchi H, Mori M, Nakayama KI, Shimamura T, Shibata T, Mimori K. Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma. British journal of cancer. 2023.06; 128 (12): 2206-2217. ( PubMed, DOI )

Azekawa S, Chubachi S, Asakura T, Namkoong H, Sato Y, Edahiro R, Lee H, Tanaka H, Otake S, Nakagawara K, Fukushima T, Watase M, Sakurai K, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force. Serum KL-6 levels predict clinical outcomes and are associated with MUC1 polymorphism in Japanese patients with COVID-19. BMJ open respiratory research. 2023.05; 10 (1): ( PubMed, DOI )

Kaburagi T, Shiba N, Yamato G, Yoshida K, Tabuchi K, Ohki K, Ishikita E, Hara Y, Shiraishi Y, Kawasaki H, Sotomatsu M, Takizawa T, Taki T, Kiyokawa N, Tomizawa D, Horibe K, Miyano S, Taga T, Adachi S, Ogawa S, Hayashi Y. UBTF-internal tandem duplication as a novel poor prognostic factor in pediatric acute myeloid leukemia. Genes, chromosomes & cancer. 2023.04; 62 (4): 202-209. ( PubMed, DOI )

Washimi K, Kasajima R, Shimizu E, Sato S, Okubo Y, Yoshioka E, Narimatsu H, Hiruma T, Katayama K, Yamaguchi R, Yamaguchi K, Furukawa Y, Miyano S, Imoto S, Yokose T, Miyagi Y. Histological markers, sickle-shaped blood vessels, myxoid area, and infiltrating growth pattern help stratify the prognosis of patients with myxofibrosarcoma/undifferentiated sarcoma. Scientific reports. 2023.04; 13 (1): 6744. ( PubMed, DOI )

Yamaguchi K, Nakagawa S, Saku A, Isobe Y, Yamaguchi R, Sheridan P, Takane K, Ikenoue T, Zhu C, Miura M, Okawara Y, Nagatoishi S, Kozuka-Hata H, Oyama M, Aikou S, Ahiko Y, Shida D, Tsumoto K, Miyano S, Imoto S, Furukawa Y. Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex. iScience. 2023.04; 26 (4): 106563. ( PubMed, DOI )

Nakagawara K, Kamata H, Chubachi S, Namkoong H, Tanaka H, Lee H, Otake S, Fukushima T, Kusumoto T, Morita A, Azekawa S, Watase M, Asakura T, Masaki K, Ishii M, Endo A, Koike R, Ishikura H, Takata T, Matsushita Y, Harada N, Kokutou H, Yoshiyama T, Kataoka K, Mutoh Y, Miyawaki M, Ueda S, Ono H, Ono T, Shoko T, Muranaka H, Kawamura K, Mori N, Mochimaru T, Fukui M, Chihara Y, Nagasaki Y, Okamoto M, Amishima M, Odani T, Tani M, Nishi K, Shirai Y, Edahiro R, Ando A, Hashimoto N, Ogura S, Kitagawa Y, Kita T, Kagaya T, Kimura Y, Miyazawa N, Tsuchida T, Fujitani S, Murakami K, Sano H, Sato Y, Tanino Y, Otsuki R, Mashimo S, Kuramochi M, Hosoda Y, Hasegawa Y, Ueda T, Takaku Y, Ishiguro T, Fujiwara A, Kuwahara N, Kitamura H, Hagiwara E, Nakamori Y, Saito F, Kono Y, Abe S, Ishii T, Ohba T, Kusaka Y, Watanabe H, Masuda M, Watanabe H, Kimizuka Y, Kawana A, Kasamatsu Y, Hashimoto S, Okada Y, Takano T, Katayama K, Ai M, Kumanogoh A, Sato T, Tokunaga K, Imoto S, Kitagawa Y, Kimura A, Miyano S, Hasegawa N, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force. Impact of respiratory bacterial infections on mortality in Japanese patients with COVID-19: a retrospective cohort study. BMC pulmonary medicine. 2023.04; 23 (1): 146. ( PubMed, DOI )

Nakagawara K, Kamata H, Chubachi S, Namkoong H, Tanaka H, Lee H, Otake S, Fukushima T, Kusumoto T, Morita A, Azekawa S, Watase M, Asakura T, Masaki K, Ishii M, Endo A, Koike R, Ishikura H, Takata T, Matsushita Y, Harada N, Kokutou H, Yoshiyama T, Kataoka K, Mutoh Y, Miyawaki M, Ueda S, Ono H, Ono T, Shoko T, Muranaka H, Kawamura K, Mori N, Mochimaru T, Fukui M, Chihara Y, Nagasaki Y, Okamoto M, Amishima M, Odani T, Tani M, Nishi K, Shirai Y, Edahiro R, Ando A, Hashimoto N, Ogura S, Kitagawa Y, Kita T, Kagaya T, Kimura Y, Miyazawa N, Tsuchida T, Fujitani S, Murakami K, Sano H, Sato Y, Tanino Y, Otsuki R, Mashimo S, Kuramochi M, Hosoda Y, Hasegawa Y, Ueda T, Takaku Y, Ishiguro T, Fujiwara A, Kuwahara N, Kitamura H, Hagiwara E, Nakamori Y, Saito F, Kono Y, Abe S, Ishii T, Ohba T, Kusaka Y, Watanabe H, Masuda M, Watanabe H, Kimizuka Y, Kawana A, Kasamatsu Y, Hashimoto S, Okada Y, Takano T, Katayama K, Ai M, Kumanogoh A, Sato T, Tokunaga K, Imoto S, Kitagawa Y, Kimura A, Miyano S, Hasegawa N, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force. Diagnostic significance of secondary bacteremia in patients with COVID-19. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2023.04; 29 (4): 422-426. ( PubMed, DOI )

Watase M, Masaki K, Chubachi S, Namkoong H, Tanaka H, Lee H, Fukushima T, Otake S, Nakagawara K, Kusumoto T, Asakura T, Kamata H, Ishii M, Hasegawa N, Oyamada Y, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Edahiro R, Sano H, Sato Y, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force. Impact of accumulative smoking exposure and chronic obstructive pulmonary disease on COVID-19 outcomes: report based on findings from the Japan COVID-19 task force. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2023.03; 128 121-127. ( PubMed, DOI )

Nannya Y, Tobiasson M, Sato S, Bernard E, Ohtake S, Takeda J, Creignou M, Zhao L, Kusakabe M, Shibata Y, Nakamura N, Watanabe M, Hiramoto N, Shiozawa Y, Shiraishi Y, Tanaka H, Yoshida K, Kakiuchi N, Makishima H, Nakagawa MM, Usuki K, Watanabe M, Imada K, Handa H, Taguchi M, Kiguchi T, Ohyashiki K, Ishikawa T, Takaori-Kondo A, Tsurumi H, Kasahara S, Chiba S, Naoe T, Miyano S, Papaemmanuil E, Miyazaki Y, Hellström Lindberg E, Ogawa S. Post-azacitidine clone size predicts outcome of patients with myelodysplastic syndromes and related myeloid neoplasms. Blood advances. 2023.03; 7 (14): 3624-3636. ( PubMed, DOI )

Makishima H, Saiki R, Nannya Y, Korotev S, Gurnari C, Takeda J, Momozawa Y, Best S, Krishnamurthy P, Yoshizato T, Atsuta Y, Shiozawa Y, Iijima-Yamashita Y, Yoshida K, Shiraishi Y, Nagata Y, Kakiuchi N, Onizuka M, Chiba K, Tanaka H, Kon A, Ochi Y, Nakagawa MM, Okuda R, Mori T, Yoda A, Itonaga H, Miyazaki Y, Sanada M, Ishikawa T, Chiba S, Tsurumi H, Kasahara S, Müller-Tidow C, Takaori-Kondo A, Ohyashiki K, Kiguchi T, Matsuda F, Jansen JH, Polprasert C, Blombery P, Kamatani Y, Miyano S, Malcovati L, Haferlach T, Kubo M, Cazzola M, Kulasekararaj AG, Godley LA, Maciejewski JP, Ogawa S. Germ line DDX41 mutations define a unique subtype of myeloid neoplasms. Blood. 2023.02; 141 (5): 534-549. ( PubMed, DOI )

Park H, Imoto S, Miyano S. Gene Regulatory Network-Classifier: Gene Regulatory Network-Based Classifier and Its Applications to Gastric Cancer Drug (5-Fluorouracil) Marker Identification. Journal of computational biology : a journal of computational molecular cell biology. 2023.02; 30 (2): 223-243. ( PubMed, DOI )

Fukushima T, Chubachi S, Namkoong H, Asakura T, Tanaka H, Lee H, Azekawa S, Okada Y, Koike R, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force. Clinical significance of prediabetes, undiagnosed diabetes and diagnosed diabetes on critical outcomes in COVID-19: Integrative analysis from the Japan COVID-19 task force. Diabetes, obesity & metabolism. 2023.01; 25 (1): 144-155. ( PubMed, DOI )

Park H, Imoto S, Miyano S. Comprehensive information-based differential gene regulatory networks analysis (CIdrgn): Application to gastric cancer and chemotherapy-responsive gene network identification. PloS one. 2023; 18 (8): e0286044. ( PubMed, DOI )

Lee H, Chubachi S, Namkoong H, Asakura T, Tanaka H, Otake S, Nakagawara K, Morita A, Fukushima T, Watase M, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force. Characteristics of hospitalized patients with COVID-19 during the first to fifth waves of infection: a report from the Japan COVID-19 Task Force. BMC infectious diseases. 2022.12; 22 (1): 935. ( PubMed, DOI )

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Nakagawara K, Chubachi S, Namkoong H, Tanaka H, Lee H, Azekawa S, Otake S, Fukushima T, Morita A, Watase M, Sakurai K, Kusumoto T, Asakura T, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Edahiro R, Murakami K, Sato Y, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K. Impact of upper and lower respiratory symptoms on COVID-19 outcomes: a multicenter retrospective cohort study. Respiratory research. 2022.11; 23 (1): 315. ( PubMed, DOI )

Watanabe K, Kimura S, Seki M, Isobe T, Kubota Y, Sekiguchi M, Sato-Otsubo A, Hiwatari M, Kato M, Oka A, Koh K, Sato Y, Tanaka H, Miyano S, Kawai T, Hata K, Ueno H, Nannya Y, Suzuki H, Yoshida K, Fujii Y, Nagae G, Aburatani H, Ogawa S, Takita J. Identification of the ultrahigh-risk subgroup in neuroblastoma cases through DNA methylation analysis and its treatment exploiting cancer metabolism. Oncogene. 2022.11; 41 (46): 4994-5007. ( PubMed, DOI )

Park H, Miyano S. Computational Tactics for Precision Cancer Network Biology. International journal of molecular sciences. 2022.11; 23 (22): ( PubMed, DOI )

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Otake S, Chubachi S, Namkoong H, Nakagawara K, Tanaka H, Lee H, Morita A, Fukushima T, Watase M, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force. Clinical clustering with prognostic implications in Japanese COVID-19 patients: report from Japan COVID-19 Task Force, a nation-wide consortium to investigate COVID-19 host genetics. BMC infectious diseases. 2022.09; 22 (1): 735. ( PubMed, DOI )

Takeuchi Y, Yoshida K, Halik A, Kunitz A, Suzuki H, Kakiuchi N, Shiozawa Y, Yokoyama A, Inoue Y, Hirano T, Yoshizato T, Aoki K, Fujii Y, Nannya Y, Makishima H, Pfitzner BM, Bullinger L, Hirata M, Jinnouchi K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Okamoto T, Haga H, Ogawa S, Damm F. The landscape of genetic aberrations in myxofibrosarcoma. International journal of cancer. 2022.08; 151 (4): 565-577. ( PubMed, DOI )

Park H, Imoto S, Miyano S. PredictiveNetwork: predictive gene network estimation with application to gastric cancer drug response-predictive network analysis. BMC bioinformatics. 2022.08; 23 (1): 342. ( PubMed, DOI )

Bai Z, Zhang YZ, Miyano S, Yamaguchi R, Fujimoto K, Uematsu S, Imoto S. Identification of bacteriophage genome sequences with representation learning. Bioinformatics (Oxford, England). 2022.08; 38 (18): 4264-4270. ( PubMed, DOI )

Lee H, Chubachi S, Namkoong H, Tanaka H, Otake S, Nakagawara K, Morita A, Fukushima T, Watase M, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force.. Effects of mild obesity on outcomes in Japanese patients with COVID-19: a nationwide consortium to investigate COVID-19 host genetics. Nutrition & diabetes. 2022.08; 12 (1): 38. ( PubMed, DOI )

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Isobe T, Takagi M, Sato-Otsubo A, Nishimura A, Nagae G, Yamagishi C, Tamura M, Tanaka Y, Asada S, Takeda R, Tsuchiya A, Wang X, Yoshida K, Nannya Y, Ueno H, Akazawa R, Kato I, Mikami T, Watanabe K, Sekiguchi M, Seki M, Kimura S, Hiwatari M, Kato M, Fukuda S, Tatsuno K, Tsutsumi S, Kanai A, Inaba T, Shiozawa Y, Shiraishi Y, Chiba K, Tanaka H, Kotecha RS, Cruickshank MN, Ishikawa F, Morio T, Eguchi M, Deguchi T, Kiyokawa N, Arakawa Y, Koh K, Aoki Y, Ishihara T, Tomizawa D, Miyamura T, Ishii E, Mizutani S, Wilson NK, Göttgens B, Miyano S, Kitamura T, Goyama S, Yokoyama A, Aburatani H, Ogawa S, Takita J. Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia. Nature communications. 2022.08; 13 (1): 4501. ( PubMed, DOI )

Fukushima T, Chubachi S, Namkoong H, Otake S, Nakagawara K, Tanaka H, Lee H, Morita A, Watase M, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force.. U-shaped association between abnormal serum uric acid levels and COVID-19 severity: Reports from the Japan COVID-19 Task Force. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2022.07; 122 747-754. ( PubMed, DOI )

Takeda J, Yoshida K, Nakagawa MM, Nannya Y, Yoda A, Saiki R, Ochi Y, Zhao L, Okuda R, Qi X, Mori T, Kon A, Chiba K, Tanaka H, Shiraishi Y, Kuo MC, Kerr CM, Nagata Y, Morishita D, Hiramoto N, Hangaishi A, Nakazawa H, Ishiyama K, Miyano S, Chiba S, Miyazaki Y, Kitano T, Usuki K, Sezaki N, Tsurumi H, Miyawaki S, Maciejewski JP, Ishikawa T, Ohyashiki K, Ganser A, Heuser M, Thol F, Shih LY, Takaori-Kondo A, Makishima H, Ogawa S. Amplified EPOR/JAK2 genes define a unique subtype of acute erythroid leukemia. Blood cancer discovery. 2022.07; 3 (5): 410-427. ( PubMed, DOI )

Morita Y, Nannya Y, Ichikawa M, Hanamoto H, Shibayama H, Maeda Y, Hata T, Miyamoto T, Kawabata H, Takeuchi K, Tanaka H, Kishimoto J, Miyano S, Matsumura I, Ogawa S, Akashi K, Kanakura Y, Mitani K. ASXL1 mutations with serum EPO levels predict poor response to darbepoetin alfa in lower-risk MDS: W-JHS MDS01 trial. International journal of hematology. 2022.07; 116 (5): 659-668. ( PubMed, DOI )

Yamato G, Kawai T, Shiba N, Ikeda J, Hara Y, Ohki K, Tsujimoto SI, Kaburagi T, Yoshida K, Shiraishi Y, Miyano S, Kiyokawa N, Tomizawa D, Shimada A, Sotomatsu M, Arakawa H, Adachi S, Taga T, Horibe K, Ogawa S, Hata K, Hayashi Y. Genome-wide DNA methylation analysis in pediatric acute myeloid leukemia. Blood advances. 2022.06; 6 (11): 3207-3219. ( PubMed, DOI )

Ogasawara T, Fujii Y, Kakiuchi N, Shiozawa Y, Sakamoto R, Ogawa Y, Ootani K, Ito E, Tanaka T, Watanabe K, Yoshida Y, Kimura N, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S. Genetic analysis of pheochromocytoma and paraganglioma complicating cyanotic congenital heart disease. The Journal of clinical endocrinology and metabolism. 2022.06; 107 (9): 2545-2555. ( PubMed, DOI )

Maeda F, Kato A, Takeshima K, Shibazaki M, Sato R, Shibata T, Miyake K, Kozuka-Hata H, Oyama M, Shimizu E, Imoto S, Miyano S, Adachi S, Natsume T, Takeuchi K, Maruzuru Y, Koyanagi N, Jun A, Yasushi K. Role of the Orphan Transporter SLC35E1 in the Nuclear Egress of Herpes Simplex Virus 1. Journal of virology. 2022.05; 96 (10): e0030622. ( PubMed, DOI )

Hiwatari M, Seki M, Matsuno R, Yoshida K, Nagasawa T, Sato-Otsubo A, Yamamoto S, Kato M, Watanabe K, Sekiguchi M, Miyano S, Ogawa S, Takita J. Novel TENM3-ALK fusion is an alternate mechanism for ALK activation in neuroblastoma. Oncogene. 2022.05; 41 (20): 2789-2797. ( PubMed, DOI )

Kato H, Maezawa Y, Nishijima D, Iwamoto E, Takeda J, Kanamori T, Yamaga M, Mishina T, Takeda Y, Izumi S, Hino Y, Nishi H, Ishiko J, Takeuchi M, Kaneko H, Koshizaka M, Mimura N, Kuzuya M, Sakaida E, Takemoto M, Shiraishi Y, Miyano S, Ogawa S, Iwama A, Sanada M, Yokote K. A high prevalence of myeloid malignancies in progeria with Werner syndrome is associated with p53 insufficiency. Experimental hematology. 2022.05; 109 11-17. ( PubMed, DOI )

Park H, Yamaguchi R, Imoto S, Miyano S. Uncovering Molecular Mechanisms of Drug Resistance via Network-Constrained Common Structure Identification. Journal of computational biology : a journal of computational molecular cell biology. 2022.03; 29 (3): 257-275. ( PubMed, DOI )

Kogure Y, Kameda T, Koya J, Yoshimitsu M, Nosaka K, Yasunaga JI, Imaizumi Y, Watanabe M, Saito Y, Ito Y, McClure MB, Tabata M, Shingaki S, Yoshifuji K, Chiba K, Okada A, Kakiuchi N, Nannya Y, Kamiunten A, Tahira Y, Akizuki K, Sekine M, Shide K, Hidaka T, Kubuki Y, Kitanaka A, Hidaka M, Nakano N, Utsunomiya A, Sica RA, Acuna-Villaorduna A, Janakiram M, Shah U, Ramos JC, Shibata T, Takeuchi K, Takaori-Kondo A, Miyazaki Y, Matsuoka M, Ishitsuka K, Shiraishi Y, Miyano S, Ogawa S, Ye BH, Shimoda K, Kataoka K. Whole-genome landscape of adult T-cell leukemia/lymphoma. Blood. 2022.02; 139 (7): 967-982. ( PubMed, DOI )

Kobayashi A, Ohtaka R, Toki T, Hara J, Muramatsu H, Kanezaki R, Takahashi Y, Sato T, Kamio T, Kudo K, Sasaki S, Yoshida T, Utsugisawa T, Kanno H, Yoshida K, Nannya Y, Takahashi Y, Kojima S, Miyano S, Ogawa S, Terui K, Ito E. Dyserythropoietic anaemia with an intronic <i>GATA1</i> splicing mutation in patients suspected to have Diamond-Blackfan anaemia. EJHaem. 2022.02; 3 (1): 163-167. ( PubMed, DOI )

Yaguchi T, Kimura S, Sekiguchi M, Kubota Y, Seki M, Yoshida K, Shiraishi Y, Kataoka K, Fujii Y, Watanabe K, Hiwatari M, Miyano S, Ogawa S, Takita J. Description of longitudinal tumor evolution in a case of multiply relapsed clear cell sarcoma of the kidney. Cancer reports (Hoboken, N.J.). 2022.02; 5 (2): e1458. ( PubMed, DOI )

Mikami T, Kato I, Wing JB, Ueno H, Tasaka K, Tanaka K, Kubota H, Saida S, Umeda K, Hiramatsu H, Isobe T, Hiwatari M, Okada A, Chiba K, Shiraishi Y, Tanaka H, Miyano S, Arakawa Y, Oshima K, Koh K, Adachi S, Iwaisako K, Ogawa S, Sakaguchi S, Takita J. Alteration of the immune environment in bone marrow from children with recurrent B cell precursor acute lymphoblastic leukemia. Cancer science. 2022.01; 113 (1): 41-52. ( PubMed, DOI )

Park H, Yamaguchi R, Imoto S, Miyano S. Xprediction: Explainable EGFR-TKIs response prediction based on drug sensitivity specific gene networks. PloS one. 2022; 17 (5): e0261630. ( PubMed, DOI )

Takeda R, Yokoyama K, Fukuyama T, Kawamata T, Ito M, Yusa N, Kasajima R, Shimizu E, Ohno N, Uchimaru K, Yamaguchi R, Imoto S, Miyano S, Tojo A. Repeated Lineage Switches in an Elderly Case of Refractory B-Cell Acute Lymphoblastic Leukemia With <i>MLL</i> Gene Amplification: A Case Report and Literature Review. Frontiers in oncology. 2022; 12 799982. ( PubMed, DOI )

Kazama S, Yokoyama K, Ueki T, Kazumoto H, Satomi H, Sumi M, Ito I, Yusa N, Kasajima R, Shimizu E, Yamaguchi R, Imoto S, Miyano S, Tanaka Y, Denda T, Ota Y, Tojo A, Kobayashi H. Case report: Common clonal origin of concurrent langerhans cell histiocytosis and acute myeloid leukemia. Frontiers in oncology. 2022; 12 974307. ( PubMed, DOI )

Lu L, Qin J, Chen J, Yu N, Miyano S, Deng Z, Li C. Recent computational drug repositioning strategies against SARS-CoV-2. Computational and structural biotechnology journal. 2022; 20 5713-5728. ( PubMed, DOI )

24. COVID-19 Host Genetics Initiative (author list: Japan Coronavirus Taskforce Admin Team Lead: Takanori Kanai, Satoru Miyano, Seishi Ogawa). . Mapping the human genetic architecture of COVID-19. Nature. 2021.12; 600 (7889): 472-477. ( PubMed, DOI )

Tanaka H, Lee H, Morita A, Namkoong H, Chubachi S, Kabata H, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Japan COVID-19 Task Force.. Clinical Characteristics of Patients with Coronavirus Disease (COVID-19): Preliminary Baseline Report of Japan COVID-19 Task Force, a Nationwide Consortium to Investigate Host Genetics of COVID-19. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2021.12; 113 74-81. ( PubMed, DOI )

Yada E, Kasajima R, Niida A, Imoto S, Miyano S, Miyagi Y, Sasada T, Wada S. Possible Role of Cytochrome P450 1B1 in the Mechanism of Gemcitabine Resistance in Pancreatic Cancer. Biomedicines. 2021.10; 9 (10): ( PubMed, DOI )

Hirata H, Niida A, Kakiuchi N, Uchi R, Sugimachi K, Masuda T, Saito T, Kageyama SI, Motomura Y, Ito S, Yoshitake T, Tsurumaru D, Nishimuta Y, Yokoyama A, Hasegawa T, Chiba K, Shiraishi Y, Du J, Miura F, Morita M, Toh Y, Hirakawa M, Shioyama Y, Ito T, Akimoto T, Miyano S, Shibata T, Mori M, Suzuki Y, Ogawa S, Ishigami K, Mimori K. The Evolving Genomic Landscape of Esophageal Squamous Cell Carcinoma Under Chemoradiotherapy. Cancer research. 2021.10; 81 (19): 4926-4938. ( PubMed, DOI )

Zhang YZ, Imoto S, Miyano S, Yamaguchi R. Enhancing breakpoint resolution with deep segmentation model: A general refinement method for read-depth based structural variant callers. PLoS computational biology. 2021.10; 17 (10): e1009186. ( PubMed, DOI )

Matsui Y, Abe Y, Uno K, Miyano S. RoDiCE: robust differential protein co-expression analysis for cancer complexome. Bioinformatics (Oxford, England). 2021.09; 38 (5): 1269-1276. ( PubMed, DOI )

Mizuno S, Yamaguchi R, Hasegawa T, Hayashi S, Fujita M, Zhang F, Koh Y, Lee SY, Yoon SS, Shimizu E, Komura M, Fujimoto A, Nagai M, Kato M, Liang H, Miyano S, Zhang Z, Nakagawa H, Imoto S. Immunogenomic pan-cancer landscape reveals immune escape mechanisms and immunoediting histories. Scientific reports. 2021.08; 11 (1): 15713. ( PubMed, DOI )

Saiki R, Momozawa Y, Nannya Y, Nakagawa MM, Ochi Y, Yoshizato T, Terao C, Kuroda Y, Shiraishi Y, Chiba K, Tanaka H, Niida A, Imoto S, Matsuda K, Morisaki T, Murakami Y, Kamatani Y, Matsuda S, Kubo M, Miyano S, Makishima H, Ogawa S. Combined landscape of single-nucleotide variants and copy number alterations in clonal hematopoiesis. Nature medicine. 2021.07; 27 (7): 1239-1249. ( PubMed, DOI )

Fujii Y, Sato Y, Suzuki H, Kakiuchi N, Yoshizato T, Lenis AT, Maekawa S, Yokoyama A, Takeuchi Y, Inoue Y, Ochi Y, Shiozawa Y, Aoki K, Yoshida K, Kataoka K, Nakagawa MM, Nannya Y, Makishima H, Miyakawa J, Kawai T, Morikawa T, Shiraishi Y, Chiba K, Tanaka H, Nagae G, Sanada M, Sugihara E, Sato TA, Nakagawa T, Fukayama M, Ushiku T, Aburatani H, Miyano S, Coleman JA, Homma Y, Solit DB, Kume H, Ogawa S. Molecular classification and diagnostics of upper urinary tract urothelial carcinoma. Cancer cell. 2021.06; 39 (6): 793-809.e8. ( PubMed, DOI )

Yamaguchi K, Kasajima R, Takane K, Hatakeyama S, Shimizu E, Yamaguchi R, Katayama K, Arai M, Ishioka C, Iwama T, Kaneko S, Matsubara N, Moriya Y, Nomizu T, Sugano K, Tamura K, Tomita N, Yoshida T, Sugihara K, Nakamura Y, Miyano S, Imoto S, Furukawa Y, Ikenoue T. Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome. Journal of human genetics. 2021.05; 66 (11): 1053-1060. ( PubMed, DOI )

Niida A, Mimori K, Shibata T, Miyano S. Modeling colorectal cancer evolution. Journal of human genetics. 2021.05; 66 (9): 869-878. ( PubMed, DOI )

Ochi Y, Yoshida K, Huang YJ, Kuo MC, Nannya Y, Sasaki K, Mitani K, Hosoya N, Hiramoto N, Ishikawa T, Branford S, Shanmuganathan N, Ohyashiki K, Takahashi N, Takaku T, Tsuchiya S, Kanemura N, Nakamura N, Ueda Y, Yoshihara S, Bera R, Shiozawa Y, Zhao L, Takeda J, Watatani Y, Okuda R, Makishima H, Shiraishi Y, Chiba K, Tanaka H, Sanada M, Takaori-Kondo A, Miyano S, Ogawa S, Shih LY. Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia. Nature communications. 2021.05; 12 (1): 2833. ( PubMed, DOI )

Yoshihiro Ishida, Nobuyuki Kakiuchi, Kenichi Yoshida, Yoshikage Inoue, Hiroyuki Irie, Tatsuki R Kataoka, Masahiro Hirata, Takeru Funakoshi, Shigeto Matsushita, Hiroo Hata, Hiroshi Uchi, Yuki Yamamoto, Yasuhiro Fujisawa, Taku Fujimura, Ryunosuke Saiki, Kengo Takeuchi, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Atsushi Otsuka, Satoru Miyano, Kenji Kabashima, Seishi Ogawa. Unbiased Detection of Driver Mutations in Extramammary Paget Disease. Clin Cancer Res. 2021.03; 27 (6): 1756-1765. ( PubMed, DOI )

Kazuyuki Shimada, Kenichi Yoshida, Yasuhiro Suzuki, Chisako Iriyama, Yoshikage Inoue, Masashi Sanada, Keisuke Kataoka, Masaaki Yuge, Yusuke Takagi, Shigeru Kusumoto, Yasufumi Masaki, Takahiko Ito, Yuichiro Inagaki, Akinao Okamoto, Yachiyo Kuwatsuka, Masahiro Nakatochi, Satoko Shimada, Hiroaki Miyoshi, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Yusuke Shiozawa, Yasuhito Nannya, Asako Okabe, Kei Kohno, Yoshiko Atsuta, Koichi Ohshima, Shigeo Nakamura, Seishi Ogawa, Akihiro Tomita, Hitoshi Kiyoi. Frequent genetic alterations in immune checkpoint-related genes in intravascular large B-cell lymphoma. Blood. 2021.03; 137 (11): 1491-1502. ( PubMed, DOI )

Chen Li, Jiale Qin, Keisuke Kuroyanagi, Lu Lu, Masao Nagasaki, Miyano Satoru. High-speed parameter search of dynamic biological pathways from time-course transcriptomic profiles using high-level Petri net. Biosystems. 2021.03; 201 104332. ( PubMed, DOI )

Taeko Kaburagi, Genki Yamato, Norio Shiba, Kenichi Yoshida, Yusuke Hara, Ken Tabuchi, Yuichi Shiraishi, Kentaro Ohki, Manabu Sotomatsu, Hirokazu Arakawa, Hidemasa Matsuo, Akira Shimada, Tomohiko Taki, Nobutaka Kiyokawa, Daisuke Tomizawa, Keizo Horibe, Satoru Miyano, Takashi Taga, Souichi Adachi, Seishi Ogawa, Yasuhide Hayashi. Clinical significance of RAS pathway alterations in pediatric acute myeloid leukemia. Haematologica. 2021.03; Online ahead of print (3): 583-592. ( PubMed, DOI )

Suzuki M, Kasajima R, Yokose T, Ito H, Shimizu E, Hatakeyama S, Yokoyama K, Yamaguchi R, Furukawa Y, Miyano S, Imoto S, Yoshioka E, Washimi K, Okubo Y, Kawachi K, Sato S, Miyagi Y. Comprehensive molecular analysis of genomic profiles and PD-L1 expression in lung adenocarcinoma with a high-grade fetal adenocarcinoma component. Translational lung cancer research. 2021.03; 10 (3): 1292-1304. ( PubMed, DOI )

Akira Nishimura, Shinsuke Hirabayashi, Daisuke Hasegawa, Kenichi Yoshida, Yuichi Shiraishi, Miho Ashiarai, Yosuke Hosoya, Tohru Fujiwara, Hideo Harigae, Satoru Miyano, Seishi Ogawa, Atsushi Manabe. Acquisition of monosomy 7 and a RUNX1 mutation in Pearson syndrome. Pediatr Blood Cancer. 2021.02; 68 (2): e28799. ( PubMed, DOI )

Nobutaka Ebata, Masashi Fujita, Shota Sasagawa, Kazuhiro Maejima, Yuki Okawa, Yutaka Hatanaka, Tomoko Mitsuhashi, Ayako Oosawa-Tatsuguchi, Hiroko Tanaka, Satoru Miyano, Toru Nakamura, Satoshi Hirano, Hidewaki Nakagawa. Molecular Classification and Tumor Microenvironment Characterization of Gallbladder Cancer by Comprehensive Genomic and Transcriptomic Analysis. Cancers (Basel). 2021.02; 13 (4): 733. ( PubMed, DOI )

Kosuke Fujimoto, Yasumasa Kimura, Jessica R Allegretti, Mako Yamamoto, Yao-Zhong Zhang, Kotoe Katayama, Georg Tremmel, Yunosuke Kawaguchi, Masaki Shimohigoshi, Tetsuya Hayashi, Miho Uematsu, Kiyoshi Yamaguchi, Yoichi Furukawa, Yutaka Akiyama, Rui Yamaguchi, Sheila E Crowe, Peter B Ernst, Satoru Miyano, Hiroshi Kiyono, Seiya Imoto, Satoshi Uematsu. Functional Restoration of Bacteriomes and Viromes by Fecal Microbiota Transplantation. Gastroenterology. 2021.02; S0016-5085(21)00400-5 (6): 2089-2102.e12. ( PubMed, DOI )

Chantana Polprasert, Yasuhide Takeuchi, Hideki Makishima, Kitsada Wudhikarn, Nobuyuki Kakiuchi, Nichthida Tangnuntachai, Thamathorn Assanasen, Wimonmas Sitthi, Hamidah Muhamad, Panisinee Lawasut, Sunisa Kongkiatkamon, Udomsak Bunworasate, Koji Izutsu, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Seishi Ogawa, Kenichi Yoshida, Ponlapat Rojnuckarin. Frequent mutations in HLA and related genes in extranodal NK/T cell lymphomas. Leuk Lymphoma. 2021.01; 62 (1): 95-103. ( PubMed, DOI )

Fumi Nakamura, Honoka Arai, Yasuhito Nannya, Motoshi Ichikawa, Shiho Furuichi, Fusako Nagasawa, Wataru Takahashi, Tomoyuki Handa, Yuko Nakamura, Hiroko Tanaka, Yuka Nakamura, Ko Sasaki, Satoru Miyano, Seishi Ogawa, Kinuko Mitani. Development of Philadelphia chromosome-negative acute myeloid leukemia with IDH2 and NPM1 mutations in a patient with chronic myeloid leukemia who showed a major molecular response to tyrosine kinase inhibitor therapy. Int J Hematol. 2021.01; Online ahead of print (6): 936-940. ( PubMed, DOI )

Shunsuke Kimura, Masahiro Sekiguchi, Kentaro Watanabe, Mitsuteru Hiwatarai, Masafumi Seki, Kenichi Yoshida, Tomoya Isobe, Yusuke Shiozawa, Hiromichi Suzuki, Noriko Hoshino, Yasuhide Hayashi, Akira Oka, Satoru Miyano, Seishi Ogawa, Junko Takita. Association of high-risk neuroblastoma classification based on expression profiles with differentiation and metabolism. PLoS One. 2021.01; 16 (1): e0245526. ( PubMed, DOI )

Heewon Park, Koji Maruhashi, Rui Yamaguchi, Seiya Imoto, Satoru Miyano. Correction: Global gene network exploration based on explainable artificial intelligence approach. PLoS One. 2021.01; 16 (1): e0246380. ( PubMed, DOI )

Lu L, Qin J, Chen J, Wu H, Zhao Q, Miyano S, Zhang Y, Yu H, Li C. DDIT: An Online Predictor for Multiple Clinical Phenotypic Drug-Disease Associations. Frontiers in pharmacology. 2021; 12 772026. ( PubMed, DOI )

Felix A Dingler, Meng Wang, Anfeng Mu, Christopher L Millington, Nina Oberbeck, Sam Watcham, Lucas B Pontel, Ashley N Kamimae-Lanning, Frederic Langevin, Camille Nadler, Rebecca L Cordell, Paul S Monks, Rui Yu, Nicola K Wilson, Asuka Hira, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Yusuke Okuno, Hideki Muramatsu, Yuichi Shiraishi, Masayuki Kobayashi, Toshinori Moriguchi, Tomoo Osumi, Motohiro Kato, Satoru Miyano, Etsuro Ito, Seiji Kojima, Hiromasa Yabe, Miharu Yabe, Keitaro Matsuo, Seishi Ogawa, Berthold Göttgens, Michael R G Hodskinson, Minoru Takata, Ketan J Patel. Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. Mol Cell. 2020.12; 80 (6): 996-1012.e9.

Heewon Park, Rui Yamaguchi, Seiya Imoto, Satoru Miyano. Automatic sparse principal component analysis The Canadian J Statistics. 2020.12; Online ahead of print ( DOI )

Felix A Dingler, Meng Wang, Anfeng Mu, Christopher L Millington, Nina Oberbeck, Sam Watcham, Lucas B Pontel, Ashley N Kamimae-Lanning, Frederic Langevin, Camille Nadler, Rebecca L Cordell, Paul S Monks, Rui Yu, Nicola K Wilson, Asuka Hira, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Yusuke Okuno, Hideki Muramatsu, Yuichi Shiraishi, Masayuki Kobayashi, Toshinori Moriguchi, Tomoo Osumi, Motohiro Kato, Satoru Miyano, Etsuro Ito, Seiji Kojima, Hiromasa Yabe, Miharu Yabe, Keitaro Matsuo, Seishi Ogawa, Berthold Göttgens, Michael R G Hodskinson, Minoru Takata, Ketan J Patel. Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. Mol Cell. 2020.12; 80 (6): 996-1012.e9. ( PubMed, DOI )

Takashi Kanamori, Masashi Sanada, Masaki Ri, Hiroo Ueno, Dai Nishijima, Takahiko Yasuda, Takuto Tachita, Tomoko Narita, Shigeru Kusumoto, Atsushi Inagaki, Rei Ishihara, Yuki Murakami, Nobuhiko Kobayashi, Yusuke Shiozawa, Kenichi Yoshida, Masahiro M Nakagawa, Yasuhito Nannya, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Keizo Horibe, Hiroshi Handa, Seishi Ogawa, Shinsuke Iida. Genomic analysis of multiple myeloma using targeted capture sequencing in the Japanese cohort. Br J Haematol. 2020.12; 191 (5): 755-763. ( PubMed, DOI )

Shin-Ei Kudo, Yuta Kouyama, Yushi Ogawa, Katsuro Ichimasa, Tsuyoshi Hamada, Kazuki Kato, Koki Kudo, Takaaki Masuda, Hajime Otsu, Masashi Misawa, Yuichi Mori, Toyoki Kudo, Takemasa Hayashi, Kunihiko Wakamura, Hideyuki Miyachi, Naruhiko Sawada, Toshiro Sato, Tatsuhiro Shibata, Shigeharu Hamatani, Tetsuo Nemoto, Fumio Ishida, Atsushi Niida, Satoru Miyano, Masanobu Oshima, Shuji Ogino, Koshi Mimori. Depressed Colorectal Cancer: A New Paradigm in Early Colorectal Cancer. Clin Transl Gastroenterol. 2020.12; 11 (12): e00269. ( PubMed, DOI )

Heewon Park, Koji Maruhashi, Rui Yamaguchi, Seiya Imoto, Satoru Miyano. Global gene network exploration based on explainable artificial intelligence approach. PLoS One. 2020.11; 15 (11): e0241508. ( PubMed, DOI )

Hiromi Ogura, Shouichi Ohga, Takako Aoki, Taiju Utsugisawa, Hidehiro Takahashi, Asayuki Iwai, Kenichiro Watanabe, Yusuke Okuno, Kenichi Yoshida, Seishi Ogawa, Satoru Miyano, Seiji Kojima, Toshiyuki Yamamoto, Keiko Yamamoto-Shimojima, Hitoshi Kanno. Novel COL4A1 mutations identified in infants with congenital hemolytic anemia in association with brain malformations. Hum Genome Var. 2020.11; 7 (1): 42. ( PubMed, DOI )

Matthew H Bailey, William U Meyerson, Lewis Jonathan Dursi, Liang-Bo Wang, Guanlan Dong, Wen-Wei Liang, Amila Weerasinghe, Shantao Li, Yize Li, Sean Kelso, Gordon Saksena, Kyle Ellrott, Michael C Wendl, David A Wheeler, Gad Getz, Jared T Simpson, Mark B Gerstein, Li Ding, PCAWG Consortium (Satoru Miyano, et al.). Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. Nat Commun. 2020.11; 11 (1): 6232. ( PubMed, DOI )

Sachiko Ishida, Kumiko Kato, Masami Tanaka, Toshitaka Odamaki, Ryuichi Kubo, Eri Mitsuyama, Jin-Zhong Xiao, Rui Yamaguchi, Satoshi Uematsu, Seiya Imoto, Satoru Miyano. Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Commun Biol. 2020.11; 3 (1): 686. ( PubMed, DOI )

Hijikata Y, Yokoyama K, Yokoyama N, Matsubara Y, Shimizu E, Nakashima M, Yamagishi M, Ota Y, Lim LA, Yamaguchi R, Ito M, Tanaka Y, Denda T, Tani K, Yotsuyanagi H, Imoto S, Miyano S, Uchimaru K, Tojo A. Successful Clinical Sequencing by Molecular Tumor Board in an Elderly Patient With Refractory Sézary Syndrome. JCO precision oncology. 2020.11; 4 534-560. ( PubMed, DOI )

Hidemasa Matsuo, Kenichi Yoshida, Kana Nakatani, Yutarou Harata, Moe Higashitani, Yuri Ito, Yasuhiko Kamikubo, Yusuke Shiozawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Ai Okada, Yasuhito Nannya, June Takeda, Hiroo Ueno, Nobutaka Kiyokawa, Daisuke Tomizawa, Takashi Taga, Akio Tawa, Satoru Miyano, Manja Meggendorfer, Claudia Haferlach, Seishi Ogawa, Souichi Adachi. Fusion partner-specific mutation profiles and KRAS mutations as adverse prognostic factors in MLL-rearranged AML. Blood Adv. 2020.10; 4 (19): 4623-4631. ( PubMed, DOI )

Hiroo Ueno, Kenichi Yoshida, Yusuke Shiozawa, Yasuhito Nannya, Yuka Iijima-Yamashita, Nobutaka Kiyokawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Tomoya Isobe, Masafumi Seki, Shunsuke Kimura, Hideki Makishima, Masahiro M Nakagawa, Nobuyuki Kakiuchi, Keisuke Kataoka, Tetsuichi Yoshizato, Dai Nishijima, Takao Deguchi, Kentaro Ohki, Atsushi Sato, Hiroyuki Takahashi, Yoshiko Hashii, Sadao Tokimasa, Junichi Hara, Yoshiyuki Kosaka, Koji Kato, Takeshi Inukai, Junko Takita, Toshihiko Imamura, Satoru Miyano, Atsushi Manabe, Keizo Horibe, Seishi Ogawa, Masashi Sanada. Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia. Blood Adv. 2020.10; 4 (20): 5165-5173. ( PubMed, DOI )

Takuya Moriyama, Seiya Imoto, Satoru Miyano, Rui Yamaguchi. Theoretical Foundation of the Performance of Phylogeny-Based Somatic Variant Detection Lecture Note in Bioinformatis. 2020.10; 12508 87-101. ( DOI )

Shun Koyamaishi, Takuya Kamio, Akie Kobayashi, Tomohiko Sato, Ko Kudo, Shinya Sasaki, Rika Kanezaki, Daiichiro Hasegawa, Hideki Muramatsu, Yoshiyuki Takahashi, Yoji Sasahara, Hidefumi Hiramatsu, Harumi Kakuda, Miyuki Tanaka, Masataka Ishimura, Masanori Nishi, Akira Ishiguro, Hiromasa Yabe, Takeo Sarashina, Masaki Yamamoto, Yuki Yuza, Nobuyuki Hyakuna, Kenichi Yoshida, Hitoshi Kanno, Shouichi Ohga, Akira Ohara, Seiji Kojima, Satoru Miyano, Seishi Ogawa, Tsutomu Toki, Kiminori Terui, Etsuro Ito. Correction: Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia. Bone Marrow Transplant. 2020.10; Online ahead of print (5): 1218-1219. ( PubMed, DOI )

Yukiko Inagaki-Kawata, Kenichi Yoshida, Nobuko Kawaguchi-Sakita, Masahiro Kawashima, Tomomi Nishimura, Noriko Senda, Yusuke Shiozawa, Yasuhide Takeuchi, Yoshikage Inoue, Aiko Sato-Otsubo, Yoichi Fujii, Yasuhito Nannya, Eiji Suzuki, Masahiro Takada, Hiroko Tanaka, Yuichi Shiraishi, Kenichi Chiba, Yuki Kataoka, Masae Torii, Hiroshi Yoshibayashi, Kazuhiko Yamagami, Ryuji Okamura, Yoshio Moriguchi, Hironori Kato, Shigeru Tsuyuki, Akira Yamauchi, Hirofumi Suwa, Takashi Inamoto, Satoru Miyano, Seishi Ogawa, Masakazu Toi. Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants. Commun Biol. 2020.10; 3 (1): 578. ( PubMed, DOI )

奥田 瑠璃花, 南谷 泰仁, 越智 陽太郎, 蝶名林 和久, Creignou Maria, 牧島 秀樹, 竹田 淳恵, 昆 彩奈, 宮野 悟, 半田 寛, 千葉 滋, 大屋敷 一馬, Haferlach Torsten, Lindberg Eva, 小川 誠司. 骨髄異形成症候群におけるder(1;7)の民族的、臨床的、遺伝的特徴(Distinct ethnic, clinical, and genetic characteristics of der(1;7) in myelodysplastic syndromes) 日本癌学会総会記事. 2020.10; 79回 OE7-1. ( ichushi )

Takanori Hasegawa, Shuto Hayashi, Eigo Shimizu, Shinichi Mizuno, Atsushi Niida, Rui Yamaguchi, Satoru Miyano, Hidewaki Nakagawa, Seiya Imoto. Neoantimon: a multifunctional R package for identification of tumor-specific neoantigens. Bioinformatics. 2020.09; 36 (18): 4813-4816. ( PubMed, DOI )

Shun Koyamaishi, Takuya Kamio, Akie Kobayashi, Tomohiko Sato, Ko Kudo, Shinya Sasaki, Rika Kanezaki, Daiichiro Hasegawa, Hideki Muramatsu, Yoshiyuki Takahashi, Yoji Sasahara, Hidefumi Hiramatsu, Harumi Kakuda, Miyuki Tanaka, Masataka Ishimura, Masanori Nishi, Akira Ishiguro, Hiromasa Yabe, Takeo Sarashina, Masaki Yamamoto, Yuki Yuza, Nobuyuki Hyakuna, Kenichi Yoshida, Hitoshi Kanno, Shouichi Ohga, Akira Ohara, Seiji Kojima, Satoru Miyano, Seishi Ogawa, Tsutomu Toki, Kiminori Terui, Etsuro Ito. Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia. Bone Marrow Transplant. 2020.09; 56 (5): 1013-1020. ( PubMed, DOI )

Yasuo Kubota, Masafumi Seki, Tomoko Kawai, Tomoya Isobe, Misa Yoshida, Masahiro Sekiguchi, Shunsuke Kimura, Kentaro Watanabe, Aiko Sato-Otsubo, Kenichi Yoshida, Hiromichi Suzuki, Keisuke Kataoka, Yoichi Fujii, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Mitsuteru Hiwatari, Akira Oka, Yasuhide Hayashi, Satoru Miyano, Seishi Ogawa, Kenichiro Hata, Yukichi Tanaka, Junko Takita. Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets. Commun Biol. 2020.09; 3 (1): 544. ( PubMed, DOI )

Kosuke Fujimoto, Yasumasa Kimura, Masaki Shimohigoshi, Takeshi Satoh, Shintaro Sato, Georg Tremmel, Miho Uematsu, Yunosuke Kawaguchi, Yuki Usui, Yoshiko Nakano, Tetsuya Hayashi, Koji Kashima, Yoshikazu Yuki, Kiyoshi Yamaguchi, Yoichi Furukawa, Masanori Kakuta, Yutaka Akiyama, Rui Yamaguchi, Sheila E Crowe, Peter B Ernst, Satoru Miyano, Hiroshi Kiyono, Seiya Imoto, Satoshi Uematsu. Metagenome Data on Intestinal Phage-Bacteria Associations Aids the Development of Phage Therapy against Pathobionts. Cell Host Microbe. 2020.09; 28 (3): 380-389.e9. ( PubMed, DOI )

Matthew H Bailey, William U Meyerson, Lewis Jonathan Dursi, Liang-Bo Wang, Guanlan Dong, Wen-Wei Liang, Amila Weerasinghe, Shantao Li, Yize Li, Sean Kelso, , , Gordon Saksena, Kyle Ellrott, Michael C Wendl, David A Wheeler, Gad Getz, Jared T Simpson, Mark B Gerstein, Li Ding, . Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. Nat Commun. 2020.09; 11 (1): 4748. ( PubMed, DOI )

Constance H Li, Stephenie D Prokopec, Ren X Sun, Fouad Yousif, Nathaniel Schmitz, Paul C Boutros, PCAWG Consortium (Satoru Miyano, et al.). Sex differences in oncogenic mutational processes. Nat Commun. 2020.08; 11 (1): 4330. ( PubMed, DOI )

Masahiro Sekiguchi, Masafumi Seki, Tomoko Kawai, Kenichi Yoshida, Misa Yoshida, Tomoya Isobe, Noriko Hoshino, Ryota Shirai, Mio Tanaka, Ryota Souzaki, Kentaro Watanabe, Yuki Arakawa, Yasuhito Nannya, Hiromichi Suzuki, Yoichi Fujii, Keisuke Kataoka, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Teppei Shimamura, Yusuke Sato, Aiko Sato-Otsubo, Shunsuke Kimura, Yasuo Kubota, Mitsuteru Hiwatari, Katsuyoshi Koh, Yasuhide Hayashi, Yutaka Kanamori, Mureo Kasahara, Kenichi Kohashi, Motohiro Kato, Takako Yoshioka, Kimikazu Matsumoto, Akira Oka, Tomoaki Taguchi, Masashi Sanada, Yukichi Tanaka, Satoru Miyano, Kenichiro Hata, Seishi Ogawa, Junko Takita. Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets. NPJ Precis Oncol. 2020.07; 4 20. ( PubMed, DOI )

Yuki Saito, Junji Koya, Mitsugu Araki, Yasunori Kogure, Sumito Shingaki, Mariko Tabata, Marni B McClure, Kota Yoshifuji, Shigeyuki Matsumoto, Yuta Isaka, Hiroko Tanaka, Takanori Kanai, Satoru Miyano, Yuichi Shiraishi, Yasushi Okuno, Keisuke Kataoka. Landscape and function of multiple mutations within individual oncogenes. Nature. 2020.06; 582 (7810): 95-99. ( PubMed, DOI )

Yotaro Ochi, Ayana Kon, Toyonori Sakata, Masahiro M Nakagawa, Naotaka Nakazawa, Masanori Kakuta, Keisuke Kataoka, Haruhiko Koseki, Manabu Nakayama, Daisuke Morishita, Tatsuaki Tsuruyama, Ryunosuke Saiki, Akinori Yoda, Rurika Okuda, Tetsuichi Yoshizato, Kenichi Yoshida, Yusuke Shiozawa, Yasuhito Nannya, Shinichi Kotani, Yasunori Kogure, Nobuyuki Kakiuchi, Tomomi Nishimura, Hideki Makishima, Luca Malcovati, Akihiko Yokoyama, Kengo Takeuchi, Eiji Sugihara, Taka-Aki Sato, Masashi Sanada, Akifumi Takaori-Kondo, Mario Cazzola, Mineko Kengaku, Satoru Miyano, Katsuhiko Shirahige, Hiroshi I Suzuki, Seishi Ogawa. Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes. Cancer Discov. 2020.06; 10 (6): 836-853. ( PubMed, DOI )

Munmee Dutta, Hidewaki Nakagawa, Hiroaki Kato, Kazuhiro Maejima, Shota Sasagawa, Kaoru Nakano, Aya Sasaki-Oku, Akihiro Fujimoto, Raúl Nicolás Mateos, Ashwini Patil, Hiroko Tanaka, Satoru Miyano, Takushi Yasuda, Kenta Nakai, Masashi Fujita. Whole genome sequencing analysis identifies recurrent structural alterations in esophageal squamous cell carcinoma. PeerJ. 2020.06; 8 e9294. ( PubMed, DOI )

Isidro Cortés-Ciriano, Jake June-Koo Lee, Ruibin Xi, Dhawal Jain, Youngsook L Jung, Lixing Yang, Dmitry Gordenin, Leszek J Klimczak, Cheng-Zhong Zhang, David S Pellman, Peter J Park, PCAWG Consortium (Satoru Miyano, et al.). Publisher Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. Nat Genet. 2020.05; Online ahead of print ( PubMed, DOI )

Shunsuke Kimura, Masafumi Seki, Tomoko Kawai, Hiroaki Goto, Kenichi Yoshida, Tomoya Isobe, Masahiro Sekiguchi, Kentaro Watanabe, Yasuo Kubota, Yasuhito Nannya, Hiroo Ueno, Yusuke Shiozawa, Hiromichi Suzuki, Yuichi Shiraishi, Kentaro Ohki, Motohiro Kato, Katsuyoshi Koh, Ryoji Kobayashi, Takao Deguchi, Yoshiko Hashii, Toshihiko Imamura, Atsushi Sato, Nobutaka Kiyokawa, Atsushi Manabe, Masashi Sanada, Marc R Mansour, Akira Ohara, Keizo Horibe, Masao Kobayashi, Akira Oka, Yasuhide Hayashi, Satoru Miyano, Kenichiro Hata, Seishi Ogawa, Junko Takita. DNA methylation-based classification reveals difference between pediatric T-cell acute lymphoblastic leukemia and normal thymocytes. Leukemia. 2020.04; 34 (4): 1163-1168. ( PubMed, DOI )

Atsushi Niida, Takanori Hasegawa, Hideki Innan, Tatsuhiro Shibata, Koshi Mimori, Satoru Miyano. A unified simulation model for understanding the diversity of cancer evolution. PeerJ. 2020.04; 8 e8842. ( PubMed, DOI )

Minako Mori, Asuka Hira, Kenichi Yoshida, Hideki Muramatsu, Yusuke Okuno, Yuichi Shiraishi, Michiko Anmae, Jun Yasuda, Shu Tadaka, Kengo Kinoshita, Tomoo Osumi, Yasushi Noguchi, Souichi Adachi, Ryoji Kobayashi, Hiroshi Kawabata, Kohsuke Imai, Tomohiro Morio, Kazuo Tamura, Akifumi Takaori-Kondo, Masayuki Yamamoto, Satoru Miyano, Seiji Kojima, Etsuro Ito, Seishi Ogawa, Keitaro Matsuo, Hiromasa Yabe, Miharu Yabe, Minoru Takata. Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients. Haematologica. 2020.04; 105 (4): 1166-1167. ( PubMed, DOI )

Yao-Zhong Zhang, Arda Akdemir, Georg Tremmel, Seiya Imoto, Satoru Miyano, Tetsuo Shibuya, Rui Yamaguchi. Nanopore basecalling from a perspective of instance segmentation. BMC Bioinformatics. 2020.04; 21 (Suppl 3): 136. ( PubMed, DOI )

Ayako Maeda-Minami, Tetsuhiro Yoshino, Kotoe Katayama, Yuko Horiba, Hiroaki Hikiami, Yutaka Shimada, Takao Namiki, Eiichi Tahara, Kiyoshi Minamizawa, Shinichi Muramatsu, Rui Yamaguchi, Seiya Imoto, Satoru Miyano, Hideki Mima, Masaru Mimura, Tomonori Nakamura, Kenji Watanabe. Discrimination of prediction models between cold-heat and deficiency-excess patterns. Complement Ther Med. 2020.03; 49 102353. ( PubMed, DOI )

Masashi Fujita, Rui Yamaguchi, Takanori Hasegawa, Shu Shimada, Koji Arihiro, Shuto Hayashi, Kazuhiro Maejima, Kaoru Nakano, Akihiro Fujimoto, Atsushi Ono, Hiroshi Aikata, Masaki Ueno, Shinya Hayami, Hiroko Tanaka, Satoru Miyano, Hiroki Yamaue, Kazuaki Chayama, Kazuhiro Kakimi, Shinji Tanaka, Seiya Imoto, Hidewaki Nakagawa. Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations. EBioMedicine. 2020.03; 53 102659. ( PubMed, DOI )

Raksha Shrestha, Mamiko Sakata-Yanagimoto, Koichiro Maie, Motohiko Oshima, Masatomo Ishihara, Yasuhito Suehara, Kota Fukumoto, Yaeko Nakajima-Takagi, Hirotaka Matsui, Takayasu Kato, Hideharu Muto, Tatsuhiro Sakamoto, Manabu Kusakabe, Yasuhito Nannya, Hideki Makishima, Hiroo Ueno, Ryunosuke Saiki, Seishi Ogawa, Kenichi Chiba, Yuichi Shiraishi, Satoru Miyano, Enguerran Mouly, Olivier A Bernard, Toshiya Inaba, Haruhiko Koseki, Atsushi Iwama, Shigeru Chiba. Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status. Blood Adv. 2020.03; 4 (5): 845-854. ( PubMed, DOI )

Takanori Hasegawa, Rui Yamaguchi, Atsushi Niida, Satoru Miyano, Seiya Imoto. Ensemble smoothers for inference of hidden states and parameters in combinatorial regulatory model J Frankl Inst. 2020.03; 357 (5): 2916-2933. ( DOI )

Sergei Yakneen, Sebastian M Waszak, , Michael Gertz, Jan O Korbel, PCAWG Consortium (Satoru Miyano, et al.). Butler enables rapid cloud-based analysis of thousands of human genomes. Nat Biotechnol. 2020.03; 38 (3): 288-292. ( PubMed, DOI )

Bernardo Rodriguez-Martin, Eva G Alvarez, Adrian Baez-Ortega, Jorge Zamora, Fran Supek, Jonas Demeulemeester, Martin Santamarina, Young Seok Ju, Javier Temes, Daniel Garcia-Souto, Harald Detering, Yilong Li, Jorge Rodriguez-Castro, Ana Dueso-Barroso, Alicia L Bruzos, Stefan C Dentro, Miguel G Blanco, Gianmarco Contino, Daniel Ardeljan, Marta Tojo, Nicola D Roberts, Sonia Zumalave, Paul A W Edwards, Joachim Weischenfeldt, Montserrat Puiggròs, Zechen Chong, Ken Chen, Eunjung Alice Lee, Jeremiah A Wala, Keiran Raine, Adam Butler, Sebastian M Waszak, Fabio C P Navarro, Steven E Schumacher, Jean Monlong, Francesco Maura, Niccolo Bolli, Guillaume Bourque, Mark Gerstein, Peter J Park, David C Wedge, Rameen Beroukhim, David Torrents, Jan O Korbel, Inigo Martincorena, Rebecca C Fitzgerald, Peter Van Loo, Haig H Kazazian, Kathleen H Burns, Peter J Campbell, Jose M C Tubio, PCAWG Consortium (Satoru Miyano, et al.). Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition. Nat Genet. 2020.03; 52 (3): 306-319. ( PubMed, DOI )

Kadir C Akdemir, Victoria T Le, Sahaana Chandran, Yilong Li, Roel G Verhaak, Rameen Beroukhim, Peter J Campbell, Lynda Chin, Jesse R Dixon, P Andrew Futreal, ,PCAWG Consortium (Satoru Miyano, et al.). Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer. Nat Genet. 2020.03; 52 (3): 294-305. ( PubMed, DOI )

Isidro Cortés-Ciriano, Jake June-Koo Lee, Ruibin Xi, Dhawal Jain, Youngsook L Jung, Lixing Yang, Dmitry Gordenin, Leszek J Klimczak, Cheng-Zhong Zhang, David S Pellman, Peter J Park, PCAWG Consortium (Satoru Miyano, et al.). Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. Nat Genet. 2020.03; 52 (3): 331-341. ( PubMed, DOI )

Rika Kasajima, Rui Yamaguchi, Eigo Shimizu, Yoshinori Tamada, Atsushi Niida, George Tremmel, Takeshi Kishida, Ichiro Aoki, Seiya Imoto, Satoru Miyano, Hiroji Uemura, Yohei Miyagi. Variant analysis of prostate cancer in Japanese patients and a new attempt to predict related biological pathways Oncol Rep. 2020.03; 43 (3): 943-952. ( PubMed, DOI )

Akihiro Fujimoto, Masashi Fujita, Takanori Hasegawa, Jing Hao Wong, Kazuhiro Maejima, Aya Oku-Sasaki, Kaoru Nakano, Yuichi Shiraishi, Satoru Miyano, Go Yamamoto, Kiwamu Akagi, Seiya Imoto, Hidewaki Nakagawa. Comprehensive analysis of indels in whole-genome microsatellite regions and microsatellite instability across 21 cancer types. Genome Res. 2020.03; 30 (3): 334-46. ( PubMed, DOI )

Makoto Hirata, Naofumi Asano, Kotoe Katayama, Akihiko Yoshida, Yusuke Tsuda, Masaya Sekimizu, Sachiyo Mitani, Eisuke Kobayashi, Motokiyo Komiyama, Hiroyuki Fujimoto, Takahiro Goto, Yukihide Iwamoto, Norifumi Naka, Shintaro Iwata, Yoshihiro Nishida, Toru Hiruma, Hiroaki Hiraga, Hirotaka Kawano, Toru Motoi, Yoshinao Oda, Daisuke Matsubara, Masashi Fujita, Tatsuhiro Shibata, Hidewaki Nakagawa, Robert Nakayama, Tadashi Kondo, Seiya Imoto, Satoru Miyano, Akira Kawai, Rui Yamaguchi, Hitoshi Ichikawa, Koichi Matsuda. Publisher Correction: Integrated exome and RNA sequencing of dedifferentiated liposarcoma. Nat Commun. 2020.02; 11 (1): 1024. ( PubMed, DOI )

Lina Sieverling, Chen Hong, Sandra D Koser, Philip Ginsbach, Kortine Kleinheinz, Barbara Hutter, Delia M Braun, Isidro Cortés-Ciriano, Ruibin Xi, Rolf Kabbe, Peter J Park, Roland Eils, Matthias Schlesner, , Benedikt Brors, Karsten Rippe, David T W Jones, Lars Feuerbach, PCAWG Consortium (Satoru Miyano, et al.). Genomic footprints of activated telomere maintenance mechanisms in cancer. Nat Commun. 2020.02; 11 (1): 733. ( PubMed, DOI )

Yiqun Zhang, Fengju Chen, Nuno A Fonseca, Yao He, Masashi Fujita, Hidewaki Nakagawa, Zemin Zhang, Alvis Brazma, Chad J Creighton, PCAWG Consortium (Satoru Miyano, et al.). High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations. Nat Commun. 2020.02; 11 (1): 736. ( PubMed, DOI )

Sergei Yakneen, Sebastian M Waszak, Michael Gertz, Jan O Korbel, PCAWG Consortium (Satoru Miyano, et al.). Publisher Correction: Butler enables rapid cloud-based analysis of thousands of human genomes. Nat Biotechnol. 2020.02; Online ahead of print. ( PubMed, DOI )

Esther Rheinbay, Morten Muhlig Nielsen, Federico Abascal, Jeremiah A Wala, Ofer Shapira, Grace Tiao, Henrik Hornshøj, Julian M Hess, Randi Istrup Juul, Ziao Lin, Lars Feuerbach, Radhakrishnan Sabarinathan, Tobias Madsen, Jaegil Kim, Loris Mularoni, Shimin Shuai, Andrés Lanzós, Carl Herrmann, Yosef E Maruvka, Ciyue Shen, Samirkumar B Amin, Pratiti Bandopadhayay, Johanna Bertl, Keith A Boroevich, John Busanovich, Joana Carlevaro-Fita, Dimple Chakravarty, Calvin Wing Yiu Chan, David Craft, Priyanka Dhingra, Klev Diamanti, Nuno A Fonseca, Abel Gonzalez-Perez, Qianyun Guo, Mark P Hamilton, Nicholas J Haradhvala, Chen Hong, Keren Isaev, Todd A Johnson, Malene Juul, Andre Kahles, Abdullah Kahraman, Youngwook Kim, Jan Komorowski, Kiran Kumar, Sushant Kumar, Donghoon Lee, Kjong-Van Lehmann, Yilong Li, Eric Minwei Liu, Lucas Lochovsky, Keunchil Park, Oriol Pich, Nicola D Roberts, Gordon Saksena, Steven E Schumacher, Nikos Sidiropoulos, Lina Sieverling, Nasa Sinnott-Armstrong, Chip Stewart, David Tamborero, Jose M C Tubio, Husen M Umer, Liis Uusküla-Reimand, Claes Wadelius, Lina Wadi, Xiaotong Yao, Cheng-Zhong Zhang, Jing Zhang, James E Haber, Asger Hobolth, Marcin Imielinski, Manolis Kellis, Michael S Lawrence, Christian von Mering, Hidewaki Nakagawa, Benjamin J Raphael, Mark A Rubin, Chris Sander, Lincoln D Stein, Joshua M Stuart, Tatsuhiko Tsunoda, David A Wheeler, Rory Johnson, Jüri Reimand, Mark Gerstein, Ekta Khurana, Peter J Campbell, Núria López-Bigas, Joachim Weischenfeldt, Rameen Beroukhim, Iñigo Martincorena, Jakob Skou Pedersen, Gad Getz, PCAWG Consortium. PCAWG Consortium (Satoru Miyano, et al.). Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. Nature. 2020.02; 578 (7793): 102-111. ( PubMed, DOI )

Yilong Li, Nicola D Roberts, Jeremiah A Wala, Ofer Shapira, Steven E Schumacher, Kiran Kumar, Ekta Khurana, Sebastian Waszak, Jan O Korbel, James E Haber, Marcin Imielinski, , Joachim Weischenfeldt, Rameen Beroukhim, Peter J Campbell, PCAWG Consortium (Satoru Miyano, et al.). Patterns of somatic structural variation in human cancer genomes. Nature. 2020.02; 578 (7793): 112-121. ( PubMed, DOI )

ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium (Satoru Miyano, et al.). Pan-cancer analysis of whole genomes Nature. 2020.02; 578 (7793): 82-93. ( PubMed, DOI )

Masataka Taguchi, Hiroyuki Mishima, Yusuke Shiozawa, Chisa Hayashida, Akira Kinoshita, Yasuhito Nannya, Hideki Makishima, Makiko Horai, Masatoshi Matsuo, Shinya Sato, Hidehiro Itonaga, Takeharu Kato, Hiroaki Taniguchi, Daisuke Imanishi, Yoshitaka Imaizumi, Tomoko Hata, Motoi Takenaka, Yukiyoshi Moriuchi, Yuichi Shiraishi, Satoru Miyano, Seishi Ogawa, Koh-Ichiro Yoshiura, Yasushi Miyazaki. Genome analysis of myelodysplastic syndromes among atomic bomb survivors in Nagasaki. Haematologica. 2020.01; 105 (2): 358-365. ( PubMed, DOI )

Nobuyuki Kakiuchi, Kenichi Yoshida, Motoi Uchino, Takako Kihara, Kotaro Akaki, Yoshikage Inoue, Kenji Kawada, Satoshi Nagayama, Akira Yokoyama, Shuji Yamamoto, Minoru Matsuura, Takahiro Horimatsu, Tomonori Hirano, Norihiro Goto, Yasuhide Takeuchi, Yotaro Ochi, Yusuke Shiozawa, Yasunori Kogure, Yosaku Watatani, Yoichi Fujii, Soo Ki Kim, Ayana Kon, Keisuke Kataoka, Tetsuichi Yoshizato, Masahiro M Nakagawa, Akinori Yoda, Yasuhito Nanya, Hideki Makishima, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Masashi Sanada, Eiji Sugihara, Taka-Aki Sato, Takashi Maruyama, Hiroyuki Miyoshi, Makoto Mark Taketo, Jun Oishi, Ryosaku Inagaki, Yutaka Ueda, Shinya Okamoto, Hideaki Okajima, Yoshiharu Sakai, Takaki Sakurai, Hironori Haga, Seiichi Hirota, Hiroki Ikeuchi, Hiroshi Nakase, Hiroyuki Marusawa, Tsutomu Chiba, Osamu Takeuchi, Satoru Miyano, Hiroshi Seno, Seishi Ogawa. Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis. Nature. 2020.01; 577 (7789): 260-265. ( PubMed, DOI )

A Bayesian model integration for mutation calling through data partitioning 2019.03; 35 (21): 4247-4254. ( PubMed, DOI )

A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer 2018.07; 9 (1): 2884. ( PubMed, DOI )

黒沢 貴之, 池田 順治, 河合 智子, 吉田 健一, 吉富 誠弘, 辻本 信一, 神鳥 達哉, 竹内 正宣, 奥野 友介, 加藤 元博, 富澤 大輔, 多賀 崇, 宮野 悟, 多和 昭雄, 滝田 順子, 足立 壮一, 小川 誠司, 林 泰秀, 柴 徳生. PRDM16高発現急性骨髄性白血病における難治化メカニズムの解明. 日本血液学会学術集会 2022.10.01

横山 和明, 水澤 舞, 田上 晋, 石井 敬人, 遊佐 希, 武井 智美, 清水 英吾, 長村 登紀子, 宮野 悟, 矢野 真吾, 東條 有伸, 井元 清哉, 南谷 泰仁. 治療抵抗性慢性骨髄単球性白血病の一例における新規RABEP1　FLT3融合遺伝子の白血病原性の検討. 日本血液学会学術集会 2022.10.01

高森 弘之, 植田 康敬, 松岡 由和, 藤岡 龍哉, 牧島 秀樹, 村上 良子, 木下 タロウ, 宮野 悟, 金倉 譲, 西村 純一, 保仙 直毅, 小川 誠司, 南谷 泰仁. 遺伝学的系統樹解析によるPNHクローン拡大機序の解明. 日本血液学会学術集会 2022.10.01

奥田 瑠璃花, 越智 陽太郎, 蝶名林 和久, 眞田 昌, 半田 寛, 白石 友一, 千葉 滋, 石川 隆之, 大屋敷 一馬, 熱田 由子, 宮野 悟, 牧島 秀樹, 南谷 泰仁, 小川 誠司. がん研究における女性研究者　不均衡転座der(1;7)(q10;p10)を有するMDSと関連疾患の特徴(Unbalanced translocation der(1;7)(q10;p10) as a distinct subtype in myelodysplastic syndromes). 日本癌学会総会記事 2022.09.01

池上 恒雄, 山口 貴世志, 高根 希世子, 清水 英悟, 笠島 理加, 土方 康基, 片山 琴絵, 渋谷 哲朗, 山口 類, 井元 清哉, 宮野 悟, 古川 洋一. 全ゲノム/全エクソン解析と人工知能を用いた難治がんに対する精密医療(Application of whole genome/exome sequencing and artificial intelligence for precision medicine for intractable cancer). 日本癌学会総会記事 2022.09.01

牧島 秀樹, 佐伯 龍之介, 南谷 泰仁, 竹田 淳恵, 桃沢 幸秀, 熱田 由子, 中川 正宏, 宮崎 泰司, 鶴見 寿, 笠原 千嗣, 高折 晃史, 大屋敷 一馬, 木口 亨, 松田 文彦, 宮野 悟, 小川 誠司. 全ゲノム/全エキソーム解析による生殖細胞系列多型の探索　DDX41胚細胞変異陽性骨髄腫瘍のリスク定量と臨床的特徴(Germline DDX41 mutations define a unique subtype of myeloid neoplasms). 日本癌学会総会記事 2022.09.01

山口 貴世志, 中川 沙弥, 高根 希世子, 池上 恒雄, 山口 類, 井元 清哉, 宮野 悟, 古川 洋一. ブロモドメインタンパク質BRD8を標的とした新たな大腸がん治療戦略(Targeting bromodomain protein BRD8 for colorectal cancer treatment). 日本癌学会総会記事 2022.09.01

藤井 陽一, 樋口 誠一郎, 佐藤 悠佑, 白石 友一, 宮野 悟, 久米 春喜, 市川 智彦, 岩間 厚志, 田中 知明, 小川 誠司. コルチゾール産生腺種におけるCTNNB1の新規構造異常と分子分類(Novel structural variants in CTNNB1 and molecular classification cortisol-producing adenoma). 日本癌学会総会記事 2022.09.01

平野 智紀, 垣内 伸之, 竹内 康英, 増井 俊彦, 白石 友一, 宮野 悟, 宇座 徳光, 児玉 裕三, 増田 充弘, 田中 雄志. 同時性・異時性多発膵癌の遺伝子解析(Genetic analysis of synchronous or metachronous multiple pancreatic cancers). 日本癌学会総会記事 2022.09.01

笠島 理加, 鈴木 理樹, 清水 英悟, 玉田 嘉紀, 新井田 厚司, 廣島 幸彦, 片山 琴絵, 山口 類, 山口 貴世志, 古川 洋一, 宮野 悟, 井元 清哉, 横瀬 智之, 宮城 洋平. 遺伝子ネットワーク解析による高悪性度胎児性肺腺癌のパスウェイ予測・検討(Prediction and Investigation of Pathways in High-Grade Fetal Lung Adenocarcinoma by Gene Network Analysis). 日本癌学会総会記事 2022.09.01

末原 泰人, 坂本 佳奈, 藤澤 学, 福本 浩太, 安部 佳亮, 槇島 健一, 須摩 桜子, 末永 孝生, 竹内 賢吾, 中村 直哉, 千葉 健一, 白石 友一, 宮野 悟, 小川 誠司, 千葉 滋, 坂田 麻実子[柳元]. 血管免疫芽球性T細胞リンパ腫の遺伝子異常に基づく亜分類は予後と関連する(Genetic subtypes of angioimmunoblastic T-cell lymphoma are associated with distinct outcomes.). 日本癌学会総会記事 2022.09.01

樋渡 光輝, 関 正史, 松野 良介, 吉田 健一, 長澤 武, 佐藤 亜以子, 山本 将平, 加藤 元博, 渡邉 健太郎, 関口 昌央, 宮野 悟, 小川 誠司, 滝田 順子. 神経芽腫における新規TENM 3-ALK融合遺伝子の解析(Novel ALK fusion in neuroblastoma involving TENM3, a conserved family of transmembrane protein). 日本癌学会総会記事 2022.09.01

渡部 光一, 垣内 伸之, 高松 士朗, 北村 幸子, 滝 真奈, 山ノ井 康二, 村上 隆介, 山口 建, 濱西 潤三, 田中 洋子, 宮野 悟, 万代 昌紀, 小川 誠司. 正常子宮内膜におけるクローン拡大とドライバー遺伝子変異(Clonal expansion with driver mutations in human normal endometrium.). 日本癌学会総会記事 2022.09.01

西村 友美, 垣内 伸之, 吉田 健一, 桜井 孝規, 片岡 竜貴, 澤田 守男, 竹内 康英, 前田 紘奈, 馬場 郷子, 滝田 順子, 宮野 悟, 万代 昌紀, 竹内 賢吾, 羽賀 博典, 戸井 雅和, 小川 誠司. 正常およびがん組織におけるクローン進化　乳管上皮細胞から乳癌へ至るクローン進化(Clonal evolution of mammary epithelial cells into breast cancers). 日本癌学会総会記事 2022.09.01

前田 紘奈, 垣内 伸之, 伊藤 孝司, 小川 絵里, 塩川 雅広, 宇座 徳光, 田中 洋子, 南谷 泰仁, 牧島 秀樹, 保田 宏明, 児玉 裕三, 上本 伸二, 宮野 悟, 小川 誠司. 慢性炎症に伴う胆管上皮におけるクローン拡大(Clonal expansion in bile duct associated with chronic inflammation). 日本癌学会総会記事 2022.09.01

井上 善景, 垣内 伸之, 南谷 泰仁, 吉田 健一, 竹内 康英, 藤井 陽一, 千葉 健一, 吉里 哲一, 長山 聡, 宮野 悟, 小濱 和貴, 小川 誠司. 大腸癌におけるトランスレーショナルリサーチの新たな展開　大腸癌の分子分類および予後予測リスク分類(Molecular classification and risk stratification of colorectal cancer). 日本癌学会総会記事 2022.09.01

牧島 秀樹, 南谷 泰仁, 竹田 淳恵, 桃沢 幸秀, 吉里 哲一, Gurunari Camelo, 熱田 由子, 佐伯 龍之介, 吉田 健一, 鬼塚 真仁, 中川 正宏, 神田 善伸, 宮崎 泰司, 真田 昌, 鶴見 寿, 笠原 千嗣, 高折 晃史, 大屋敷 一馬, 木口 亨, 松田 文彦, Jansen Joop, Lindberg Eva, Polprasert Chantana, Malcovati Luca, Cazzola Mario, Haferlach Torsten, Maciejewski Jaroslaw, 鎌谷 洋一郎, 宮野 悟, 小川 誠司. 骨髄腫瘍におけるDDX41胚細胞性および体細胞性変異陽性(Myeloid neoplasms with germline and somatic DDX41 mutations). 日本血液学会学術集会 2021.09.01

竹田 淳恵, 吉田 健一, 依田 成玄, 南谷 泰仁, 越智 陽太郎, 中川 正宏, 佐伯 龍之介, 白石 友一, 永田 安伸, 高折 晃史, 千葉 滋, 片岡 圭亮, 宮野 悟, 牧島 秀樹, 小川 誠司. 赤白血病におけるゲノム解析と治療標的の検討. 日本癌学会総会記事 2021.09.01

井上 善景, 垣内 伸之, 吉田 健一, 南谷 泰仁, 塩澤 裕介, 竹内 康英, 藤井 陽一, 千葉 健一, 吉里 哲一, 長山 聡, 宮野 悟, 坂井 義治, 小川 誠司. 遺伝子変異に基づく大腸癌の分類. 日本癌学会総会記事 2021.09.01

中川 沙弥, 山口 貴世志, 高根 希世子, 池上 恒雄, 清水 英悟, 山口 類, 井元 清哉, 宮野 悟, 古川 洋一. 腫瘍抑制遺伝子APCプロモーター1Aおよび1Bの解析. 日本癌学会総会記事 2021.09.01

平野 智紀, 垣内 伸之, 竹内 康英, 増井 俊彦, 白石 友一, 宮野 悟, 宇座 徳光, 田中 雄志, 増田 充弘, 児玉 裕三, 妹尾 浩, 千葉 勉, 小川 誠司. 肝胆膵がんにおける基礎および臨床研究の進展　同時性・異時性多発膵癌の遺伝子解析. 日本癌学会総会記事 2021.09.01

越智 陽太郎, 吉田 健一, 南谷 泰仁, 佐々木 光, 三谷 絹子, 細谷 紀子, 石川 隆之, 大屋敷 一馬, 高橋 直人, 塩澤 裕介, 牧島 秀樹, 白石 友一, 真田 昌, 高折 晃史, 宮野 悟, 小川 誠司. 慢性骨髄性白血病急性転化のクローン進化および遺伝子異常と予後. 日本癌学会総会記事 2021.09.01

越智 陽太郎, 吉田 健一, 南谷 泰仁, 佐々木 光, 三谷 絹子, 細谷 紀子, 平本 展大, 石川 隆之, 大屋敷 一馬, 高橋 直人, 高久 智生, 土屋 俊, 兼村 信宏, 中村 信彦, 上田 恭典, 吉原 哲, 塩澤 裕介, 趙 蘭英, 竹田 淳恵, 綿谷 陽作, 奥田 瑠璃花, 牧島 秀樹, 白石 友一, 千葉 健一, 田中 洋子, 真田 昌, 高折 晃史, 宮野 悟, Shih Lee-Yung, 小川 誠司. 慢性骨髄性白血病急性転化におけるクローン進化および遺伝子異常と予後の解析(Clonal evolution and clinical impact of genetic lesions in blast crisis of chronic myeloid leukemia). 日本血液学会学術集会 2021.09.01

前田 紘奈, 垣内 伸之, 伊藤 孝司, 小川 絵里, 塩川 雅広, 宇座 徳光, 田中 洋子, 南谷 泰仁, 牧島 秀樹, 保田 宏明, 児玉 裕三, 上本 伸二, 宮野 悟, 小川 誠司. 慢性炎症に伴う胆管上皮におけるクローン拡大. 日本癌学会総会記事 2021.09.01

大和 玄季, 河合 智子, 柴 徳生, 原 勇介, 大木 健太郎, 鏑木 多映子, 吉田 健一, 白石 友一, 宮野 悟, 清河 信敬, 富澤 大輔, 嶋田 明, 外松 学, 荒川 浩一, 足立 壮一, 多賀 崇, 堀部 敬三, 小川 誠司, 秦 健一郎, 林 泰秀. 小児急性骨髄性白血病における全ゲノムDNAメチル化解析　The JCCG-JPLSG AML-05 study(Genome-wide DNA methylation analysis in pediatric AML: The JCCG-JPLSG AML-05 study). 日本血液学会学術集会 2021.09.01

竹田 淳恵, 吉田 健一, 依田 成玄, 南谷 泰仁, Shih Leeyung, 越智 陽太郎, 白石 友一, Kerr Cassandra, 永田 安伸, 北野 俊行, 半下石 明, 石山 謙, 鶴見 寿, 宮崎 泰司, 平本 展大, 石川 隆之, 中川 正宏, 高折 晃史, 千葉 滋, 中澤 英之, Kuo Mingchung, 片岡 圭亮, 佐伯 龍之介, 眞田 昌, 臼杵 憲祐, 宮脇 修一, 宮野 悟, Maciejewski Jaroslaw, 牧島 秀樹, 小川 誠司. 急性赤白血病の治療標的と治療効果におけるバイオマーカーの検討(EPOR/JAK/STAT pathway is a promising therapeutic target in acute erythroid leukemia). 日本血液学会学術集会 2021.09.01

西村 友美, 垣内 伸之, 吉田 健一, 竹内 康英, 前田 紘奈, 塩澤 裕介, 平田 勝啓, 片岡 竜貴, 桜井 孝規, 馬場 郷子, 竹内 賢吾, 羽賀 博典, 宮野 悟, 戸井 雅和, 小川 誠司. 乳管上皮増殖性病変から乳癌へ至るクローン進化. 日本癌学会総会記事 2021.09.01

佐伯 龍之介, 桃沢 幸秀, 南谷 泰仁, 中川 正宏, 越智 陽太郎, 吉里 哲一, 白石 友一, 田中 洋子, 新井田 厚司, 井元 清哉, 松田 浩一, 村上 善則, 松田 秀一, 宮野 悟, 牧島 秀樹, 小川 誠司. クローン性造血と造血器腫瘍、心血管性疾患、固形癌の関係性　クローン性造血における遺伝子変異とコピー数異常の統合解析. 日本癌学会総会記事 2021.09.01

佐伯 龍之介, 桃沢 幸秀, 南谷 康仁, 中川 正宏, 越智 陽太郎, 吉里 哲一, 寺尾 知可史, 黒田 隆, 白石 友一, 千葉 健一, 田中 洋子, 新井田 厚司, 井元 清哉, 松田 浩一, 森崎 隆幸, 村上 善則, 鎌谷 洋一郎, 松田 秀一, 久保 充明, 宮野 悟, 牧島 秀樹, 小川 誠司. クローン性造血における単一塩基多型変異とコピー数異常の統合解析(Combined landscape of single-nucleotide variants and copy-number alterations in clonal hematopoiesis). 日本血液学会学術集会 2021.09.01

三上 貴司, 加藤 格, Wing James, 上野 浩生, 田坂 佳資, 田中 邦昭, 窪田 博仁, 才田 聡, 梅田 雄嗣, 平松 英文, 磯部 知弥, 岡田 愛, 千葉 健一, 白石 友一, 田中 洋子, 宮野 悟, 足立 壯一, 祝迫 惠子, 小川 誠司, 坂口 志文, 滝田 順子. マスサイトメトリーを用いた小児再発性B前駆細胞性急性リンパ性白血病の腫瘍免疫環境解析(Mass cytometric analysis of the tumor immune environment in children with recurrent BCP-ALL). 日本血液学会学術集会 2021.09.01

南谷 泰仁, Magnus Tobiasson, 佐藤 信也, Elsa Bernard, 大竹 茂樹, 竹田 淳恵, 趙 蘭英, 日下部 学, 柴田 悠平, 中村 信彦, 渡邊 瑞希, 平本 展大, 塩澤 裕介, 白石 友一, 牧島 秀樹, 中川 正宏, 田口 正剛, 木口 亨, 大屋敷 一馬, 石川 隆之, 高折 晃史, 鶴見 寿, 笠原 千嗣, 千葉 滋, 直江 知樹, 宮野 悟, Elli Papaemanuil, 宮崎 泰司, Eva Lindberg, 小川 誠司. MDS、AMLに対するアザシチジン治療後のクローンサイズは長期予後を予測する(Post-azacitidine clone size predicts long-term clinical outcome of patients with MDS and AML). 日本血液学会学術集会 2021.09.01

松尾 英将, 吉田 健一, 南谷 泰仁, 上久保 靖彦, 齋藤 章治, 古賀 友紀, 盛武 浩, 照井 君典, 川口 晃司, 岡本 康裕, 中山 秀樹, 簡野 美弥子, 日野 もえ子, 赤根 祐介, 井上 彰子, 嶋田 明, 後藤 裕明, 上野 浩生, 滝田 順子, 大和 玄季, 柴 徳生, 林 泰秀, 白石 友一, 宮野 悟, 清河 信敬, 富澤 大輔, 多賀 崇, 多和 昭雄, 小川 誠司, 足立 壯一. KMT2A再構成急性骨髄性白血病のクローン構造とその予後因子としての重要性(Clonal architecture and its prognostic significance in KMT2A-rearranged acute myeloid leukemia). 日本血液学会学術集会 2021.09.01

宮野 悟. AIによる創薬・診断の強化　スーパーコンピュータを用いた薬剤標的・耐性探索のためのネットワークアプローチ. 日本癌学会総会記事 2021.09.01

牧島 秀樹, 南谷 泰仁, 桃沢 幸秀, 竹田 淳恵, 宮崎 泰司, 鶴見 寿, 笠原 千嗣, 高折 晃史, 大屋敷 一馬, Lindberg Eva, Malcovati Luca, Haferlach Torsten, Maciejewski Jaroslaw, 鎌谷 洋一郎, 宮野 悟, 小川 誠司. DDX41変異陽性骨髄腫瘍の遺伝学的臨床的特徴. 日本癌学会総会記事 2021.09.01

奥田 瑠璃花, 南谷 泰仁, 越智 陽太郎, 蝶名林 和久, 牧島 秀樹, 永田 安伸, 真田 昌, 白石 友一, 宮野 悟, 熱田 由子, 笠原 千嗣, 半田 寛, 千葉 滋, 大屋敷 一馬, 小川 誠司. ETNK1変異の有無を特徴とするder(1;7)(q10;p10)を伴う骨髄異形成症候群. 日本癌学会総会記事 2021.09.01

奥田 瑠璃花, 南谷 泰人, 越智 陽太郎, 蝶名林 和久, 牧島 秀樹, 吉里 哲一, 永田 安伸, 竹田 淳恵, 吉田 健一, 眞田 昌, 昆 彩奈, 白石 雄一, 宮野 悟, 熱田 由子, 笠原 千嗣, 半田 寛, 千葉 滋, 大屋敷 一馬, 吉田 善紀, 小川 誠司. ETNK1変異の有無を特徴とするder(1;7)(q10;p10)を伴う骨髄異形成症候群(ETNK1 mutations defines a subclass of der(1;7)(q10;p10) in myelodysplastic syndromes). 日本血液学会学術集会 2021.09.01

Satoru Miyano. Digesting Cancer Big Networks by Explainable AI and Supercomputers. The 3rd R-CCS International Symposium (R-CCSIS'21) 2021.02.16 Online

渡邉 健太郎, 加登 翔太, 磯部 知弥, 緒方 瑛人, 田坂 佳資, 上野 浩生, 南谷 泰仁, 田中 洋子, 白石 友一, 千葉 健一, 梅田 雄嗣, 樋渡 光輝, 宮野 悟, 小川 誠司, 滝田 順子. 小児・AYA腫瘍の最近の進歩　難治性骨肉腫における糖鎖遺伝子の役割と治療標的としての可能性. 第79回日本癌学会学術総会 2020.10.03 リーガロイヤルホテル広島

古川 洋一、山口 貴世志、笠島 理加、清水 英悟、高根 希世子、 山口 類、井元 清哉、宮野 悟、池上 恒雄. 消化管遺伝性腫瘍の最前線. 第79回日本癌学会学術総会 2020.10.03

渡邉 健太郎、加登 翔太、磯部 知弥、緒方 瑛人、田坂 佳資、上 野 浩生、南谷 泰仁、田中 洋子、白石 友一、千葉 健一、梅田 雄嗣、樋渡 光輝、宮野 悟、小川 誠司、滝田 順子. 難治性骨肉腫における糖鎖遺伝子の役割と治療標的としての可能性. 2020.10.03 リーガロイヤルホテル広島

宮野　悟. AIとがん研究・医療との対話 - がん研究・医療のための自然言語処理と説明可能 AI. 第79回日本癌学会学術総会 2020.10.02 リーガロイヤルホテル広島

垣内 伸之、内野 基、木原 多佳子、赤木 宏太朗、井上 善景、横 山 顕礼、平野 智紀、廣田 誠一、池内 浩基、竹内 理、宮野 悟、妹尾 浩、小川 誠司. 潰瘍性大腸炎における大腸上皮クローン進化から明らかとなった大腸 がんの脆弱性. 第79回日本癌学会学術総会 2020.10.02 リーガロイヤルホテル広島

井上 善景, 垣内 伸之, 吉田 健一, 塩澤 裕介, 竹内 康英, 千葉 健一, 吉里 哲一, 長山 聡, 宮野 悟, 坂井 義治, 小川 誠司. POLE遺伝子に変異を持つ大腸癌における免疫回避機構. 日本癌学会総会記事 2020.10.01

藤田 征志、山口 類、有廣 光司、島田 周、宮野 悟、山上 裕 機、茶山 一彰、垣見 和宏、田中 真二、井元 清哉2、中川 英刀. 肝臓がんの免疫ゲノム解析. 第79回日本癌学会学術総会 2020.10.01 リーガロイヤルホテル広島

南谷 泰仁, 牧島 秀樹, 竹田 淳恵, 桃沢 幸秀, 佐伯 龍之介, 宮崎 泰司, 石川 隆之, 大屋敷 一馬, Hellstroem Lindberg Eva, Mario Cazzola, Torsten Haferlach, 鎌谷 洋一郎, 久保 充明, 宮野 悟, 小川 誠司. 骨髄系腫瘍におけるDDX41変異の意義. 日本癌学会総会記事 2020.10.01

古川 洋一, 山口 貴世志, 笠島 理加, 清水 英悟, 高根 希世子, 山口 類, 井元 清哉, 宮野 悟, 池上 恒雄. 遺伝性腫瘍-最新情報と今後の方向性　消化管遺伝性腫瘍の最前線. 日本癌学会総会記事 2020.10.01

垣内 伸之, 横山 顕礼, 内野 基, 木原 多佳子, 赤木 宏太朗, 井上 善景, 平野 智紀, 廣田 誠一, 池内 浩基, 竹内 理, 宮野 悟, 妹尾 浩, 小川 誠司. 遺伝子変異クローンによる食道および大腸組織の再構築の解明. 第79回日本癌学会学術総会 2020.10.01

笠島 理加, 鈴木 理樹, 清水 英悟, 玉田 嘉紀, 新井田 厚司, 山口 類, 井元 清哉, 古川 洋一, 宮野 悟, 横瀬 智之, 宮城 洋平. 胎児性肺癌における遺伝子ネットワーク解析. 日本癌学会総会記事 2020.10.01

大津 敬, 笠島 理加, 鷲見 公太, 廣島 幸彦, 片山 琴絵, 清水 英悟, 山口 類, 井元 清哉, 宮野 悟, 河村 大輔, 石川 俊平, 横瀬 智之, 比留間 徹, 宮城 洋平. 肉腫患者由来ゼノグラフトのRNA発現解析. 日本癌学会総会記事 2020.10.01

竹内 康英, 鈴木 啓道, 吉田 健一, 白石 友一, 垣内 伸之, 塩澤 裕介, 井上 善景, 千葉 健一, 牧島 秀樹, 宮野 悟, 羽賀 博典, Damm Frederik, 小川 誠司. 粘液線維肉腫にみられるTP53の異常と著明な遺伝的不安定性. 日本癌学会総会記事 2020.10.01

鎌谷 高志, 平田 真, 植田 幸嗣, 片山 琴絵, 山口 類, 松原 大祐, 藤田 征志, 高澤 豊, 山下 享子, 中村 卓郎, 井元 清哉, 宮野 悟, 中川 英刀, 松田 浩一, 角田 達彦. 粘液型脂肪肉腫におけるがん微小環境の免疫学的解析. 日本癌学会総会記事 2020.10.01

平野 智紀, 垣内 伸之, 竹内 康英, 増井 俊彦, 上本 伸二, 南口 早智子, 羽賀 博典, 白石 友一, 宮野 悟, 宇座 徳光, 児玉 裕三, 妹尾 浩, 千葉 勉, 小川 誠司. 異時性多発膵癌の遺伝子解析. 日本癌学会総会記事 2020.10.01

越智 陽太郎, 吉田 健一, 佐々木 光, 細谷 紀子, 塩澤 裕介, 南谷 泰仁, 石川 隆之, 白石 友一, 千葉 健一, 田中 洋子, 真田 昌, 牧島 秀樹, 高折 晃史, 宮野 悟, 三谷 絹子, 小川 誠司. 慢性骨髄性白血病急性転化の遺伝学的機序と予後. 日本癌学会総会記事 2020.10.01

竹田 淳恵, 吉田 健一, 依田 成玄, 南谷 泰仁, 中川 正宏, 越智 陽太郎, 昆 彩奈, 吉里 哲一, 塩澤 裕介, 白石 友一, 千葉 健一, 田中 洋子, 真田 昌, 宮野 悟, 牧島 秀樹, 小川 誠司. 急性赤白血病におけるJAK阻害剤の検討. 日本癌学会総会記事 2020.10.01

土方 康基, 横山 和明, 山口 貴世志, 池上 恒雄, 山口 類, 井元 清哉, 内丸 薫, 宮野 悟, 四柳 宏, 東條 有伸, 古川 洋一. 当院における標準治療不応進行がん患者を対象としたクリニカルシーケンスの検討. 日本癌学会総会記事 2020.10.01

垣内 伸之, 内野 基, 木原 多佳子, 赤木 宏太朗, 井上 善景, 横山 顕礼, 平野 智紀, 廣田 誠一, 池内 浩基, 竹内 理, 宮野 悟, 妹尾 浩, 小川 誠司. 大腸がんの診断・治療と発がん研究における新しい知見　潰瘍性大腸炎における大腸上皮クローン進化から明らかとなった大腸がんの脆弱性. 日本癌学会総会記事 2020.10.01

西村 友美, 垣内 伸之, 吉田 健一, 竹内 康英, 前田 紘奈, 塩澤 裕介, 平田 勝啓, 片岡 竜貴, 桜井 孝規, 馬場 郷子, 竹内 賢吾, 羽賀 博典, 宮野 悟, 戸井 雅和, 小川 誠司. 乳がん微小環境の特性と全身性応答、新しい治療展開　乳管上皮増殖性病変から乳癌へ至るクローン進化. 日本癌学会総会記事 2020.10.01

藤井 陽一, 佐藤 悠佑, 鈴木 啓道, 吉里 哲一, 垣内 伸之, 吉田 健一, 千葉 健一, 白石 友一, 西松 寛明, 岡根谷 利一, 真田 昌, 南谷 泰仁, 牧島 秀樹, 宮野 悟, 久米 春喜, 小川 誠司. 上部尿路上皮癌の分子分類と新規バイオマーカー. 日本癌学会総会記事 2020.10.01

関口 昌央, 関 正史, 吉田 健一, 田中 水緒, 白井 了太, 宗崎 良太, 白石 友一, 樋渡 光輝, 加藤 元博, 田口 智章, 田中 祐吉, 宮野 悟, 小川 誠司, 滝田 順子. マルチオミックス解析による肝芽腫の治療標的NQO1、ODC1の同定. 日本癌学会総会記事 2020.10.01

小笠原 辰樹, 藤井 陽一, 塩澤 裕介, 牧島 秀樹, 中村 英二郎, 田中 知明, 白石 友一, 宮野 悟, 小川 誠司. チアノーゼ性先天性心疾患に伴う多発パラガングリオーマは異なるHIF2α変異を伴う平行進化を示した. 日本癌学会総会記事 2020.10.01

佐伯 龍之介, 吉里 哲一, 白石 友一, 千葉 健一, 田中 洋子, 松田 浩一, 村上 善則, 久保 充明, 宮野 悟, 牧島 秀樹, 小川 誠司. クローン造血における遺伝子変異とコピー数異常の統合解析. 日本癌学会総会記事 2020.10.01

藤田 征志, 山口 類, 有廣 光司, 島田 周, 宮野 悟, 山上 裕機, 茶山 一彰, 垣見 和宏, 田中 真二, 井元 清哉, 中川 英刀. がん免疫ゲノム解析　肝臓がんの免疫ゲノム解析. 日本癌学会総会記事 2020.10.01

前田 紘奈、垣内 伸之、平野 智紀、竹内 康英、伊藤 孝司、 小川 絵里、塩川 雅広、宇座 徳光、田中 洋子、南谷 泰仁、牧 島 秀樹、上本 伸二、宮野 悟、小川 誠司. 慢性炎症に伴う胆管上皮におけるクローン拡大. 第79回日本癌学会学術総会 2020.10.01 リーガロイヤルホテル広島

Satoru Miyano. Cancer Big Data Challenges from Genomes to Networks. The 24th International Conference on Research in Computational Molecular Biology (RECOBM 2020) 2020.06.23 Online

Nobuyuki Kakiuchi, Kenichi Yoshida, Motoi Uchino, Takako Kihara, Akaki Kotaro, Yoshikage Inoue, Kenji Kawada, Satoshi Nagayama, Akira Yokoyama, Tomonori Hirano, Yasuhide Takeuchi, Hiroyuki Miyoshi, Yoshiharu Sakai, Hironori Haga, Seiichi Hirota, Hiroki Ikeuchi, Osamu Takeuchi, Satoru Miyano, Hiroshi Seno, Seishi Ogawa. Analysis of clonal expansion in epithelium affected by ulcerative colitis reveals frequent mutations affecting IL-17 signaling pathway and novel cancer vulnerability. AACR Annual Meeting 2020 2020.04.27 Online, Philadelphia, USA

Hirano Tomonori, Nobuyuki Kakiuchi, Yasuhide Takeuchi, Yoshikage Inoue, Tomomi Nishimura, Yoichi Fujii, Akira Yokoyama, Hideki Makishima, Toshihiko Masui, Shinji Uemoto, Sachiko Minamiguchi, Hironori Haga, Kenichi Chiba, Hiroko Tanaka, Yuichi Shiraishi, Satoru Miyano, Norimitsu Uza, Yuzo Kodama, Hiroshi Seno, Seishi Ogawa. Genetic analysis of metachronous pancreatic cancers. AACR Annual Meeting 2020 2020.04.27 Online, Philadelphia, USA

Yoichi Fujii, Yusuke Sato, Hiromichi Suzuki, Tetsuichi Yoshizato, Kenichi Yoshida, Yuichi Shiraishi, Taketo Kawai, Tohru Nakagawa, Hiroaki Nishimatsu, Toshikazu Nishimatsu, Masashi Sanada, Hideki Makishima, Satoru Miyano, Haruki Kume, Seishi Ogawa. Distinct molecular subtypes and a high diagnostic urinary biomarker of upper urinary tract urothelial carcinoma. AACR Annual Meeting 2020 2020.04.27 Online, Philadelphia, USA

Yoshikage Inoue, Nobuyuki Kakiuchi, Kenichi Yoshida, Yasuhide Takeuchi, Yusuke Shiozawa, Yuichi Shiraishi, Kenichi Chiba, Tetsuichi Yoshizato, Hiroko Tanaka, Ai Okada, Satoshi Nagayama, Satoru Miyano, Yoshiharu Sakai, Seishi Ogawa. Frequent genomic alterations to evade the immune system in colorectal cancer with POLE gene mutation. AACR Annual Meeting 2020 2020.04.27 Online, Philadelphia, USA

Yasuhide Takeuchi, Annegret Kunitz, Adriane Halik, Hiromichi Suzuki, Kenichi Yoshida, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Nobuyuki Kakiuchi, Yusuke Shiozawa, Akira Yokoyama, Yoshikage Inoue, Tetsuichi Yoshizato, Kosuke Aoki, Yoichi Fujii, Yasuhito Nannya, Hideki Makishima, Satoru Miyano, Hironori Haga, Frederik Damm, Seishi Ogawa. Frequent abnormalities in TP53 and increased genetic instability in myxofibrosarcoma. AACR Annual Meeting 2020 2020.04.27 Online, Philadelphia, USA

宮城 洋平, 笠島 理加, 山口 類, 井元 清哉, 青木 一郎, 上村 博司, 清水 英悟, 宮野 悟. 日本人における前立腺癌のバリアント分析と関連する生物学的経路の予測(Variant analysis of prostate cancer in the Japanese and prediction of related biological pathways). 日本病理学会会誌 2020.03.01

Satoru Miyano. Cancer Big Data Challenges by Supercomputers and Artificial Intelligence. International Conference on Cancer Systems Biology Beyond 2020.01.29 Sheraton Miyano Hotel Tokyo