Personnel Information

写真a

MATSUZAKI Kyoko


Job title

Assistant Professor

Graduating School 【 display / non-display

  • The University of Tokyo, Faculty of Science, 2003.03, Graduated

Graduate School 【 display / non-display

  • The University of Tokyo, Graduate School, Division of Science, Master's Course, 2005.03, Completed

  • The University of Tokyo, Graduate School, Division of Science, Doctor's Course, 2008.03, Accomplished credits for doctoral program

Campus Career 【 display / non-display

  • 2015.05
    -
    2018.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Medical Biochemistry, Assistant Professor
  • 2018.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Medical Biochemistry, Assistant Professor

External Career 【 display / non-display

  • 2009.06
    -
    2015.04
    , Assistant Professor

Research Areas 【 display / non-display

  • Medical biochemistry

  • Pathological biochemistry

 

Published Papers & Misc 【 display / non-display

  1. Caleb Kwame Sinclear, Junichi Maruyama, Shunta Nagashima, Kyoko Arimoto-Matsuzaki, Joshua Agbemefa Kuleape, Hiroaki Iwasa, Hiroshi Nishina, Yutaka Hata. Protein kinase Cα activation switches YAP1 from TEAD-mediated signaling to p73-mediated signaling. Cancer Sci. 2022.04; 113 (4): 1305-1320. ( PubMed, DOI )

  2. Joshua Agbemefa Kuleape, Shakhawoat Hossain, Caleb Kwame Sinclear, Takanobu Shimizu, Hiroaki Iwasa, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Hiroshi Nishina, Yutaka Hata. DNA Damage Triggers the Nuclear Accumulation of RASSF6 Tumor Suppressor Protein via CDK9 and BAF53 To Regulate p53 Target Gene Transcription. Mol Cell Biol. 2022.02; 42 (2): e0031021. ( PubMed, DOI )

  3. Mayu Morishita, Kyoko Arimoto-Matsuzaki, Masami Kitamura, Kyohei Niimura, Hiroaki Iwasa, Junichi Maruyama, Yuichi Hiraoka, Kohei Yamamoto, Masanobu Kitagawa, Norio Miyamura, Hiroshi Nishina, Yutaka Hata. Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice shows the implication of Rassf6 in the regulation of NF-κB signaling. Genes Cells. 2021.12; 26 (12): 999-1013. ( PubMed, DOI )

  4. Shunta Nagashima, Junichi Maruyama, Kaori Honda, Yasumitsu Kondoh, Hiroyuki Osada, Makiko Nawa, Ken-Ichi Nakahama, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Haruhiko Sugimura, Hiroaki Iwasa, Kyoko Arimoto-Matsuzaki, Hiroshi Nishina, Yutaka Hata. CSE1L promotes nuclear accumulation of transcriptional coactivator TAZ and enhances invasiveness of human cancer cells. J Biol Chem. 2021.07; 297 (1): 100803. ( PubMed, DOI )

  5. Xinliang Jiang, Junichi Maruyama, Hiroaki Iwasa, Kyoko Arimoto-Matsuzaki, Hiroshi Nishina, Yutaka Hata. Heat shock induces the nuclear accumulation of YAP1 via SRC. Exp Cell Res. 2021.02; 399 (1): 112439. ( PubMed, DOI )

  6. Takanobu Shimizu, Takeshi Nakamura, Hironori Inaba, Hiroaki Iwasa, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Takao Nakata, Hiroshi Nishina, Yutaka Hata. The RAS-interacting chaperone UNC119 drives the RASSF6-MDM2-p53 axis and antagonizes RAS-mediated malignant transformation. J Biol Chem. 2020.08; 295 (32): 11214-11230. ( PubMed, DOI )

  7. Manami Kodaka, Fengju Mao, Kyoko Arimoto-Matsuzaki, Masami Kitamura, Xiaoyin Xu, Zeyu Yang, Kentaro Nakagawa, Junichi Maruyama, Kana Ishii, Chihiro Akazawa, Takuya Oyaizu, Naoki Yamamoto, Mari Ishigami-Yuasa, Nozomi Tsuemoto, Shigeru Ito, Hiroyuki Kagechika, Hiroshi Nishina, Yutaka Hata. Characterization of a novel compound that promotes myogenesis via Akt and transcriptional co-activator with PDZ-binding motif (TAZ) in mouse C2C12 cells. PLoS One. 2020.04; 15 (4): e0231265. ( PubMed, DOI )

  8. Shikshya Timalsina, Kyoko Arimoto-Matsuzaki, Masami Kitamura, Xiaoyin Xu, Qiu Wenzhe, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Yutaka Hata. Chemical compounds that suppress hypoxia-induced stress granule formation enhance cancer drug sensitivity of human cervical cancer HeLa cells. J Biochem. 2018.11; 164 (5): 381-391. ( PubMed, DOI )

  9. Hiroaki Iwasa, Aradhan Sarkar, Takanobu Shimizu, Takeru Sawada, Shakhawoat Hossain, Xiaoyin Xu, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Kanchanamala Withanage, Kentaro Nakagawa, Hidetake Kurihara, Hidehito Kuroyanagi, Yutaka Hata. UNC119 is a binding partner of tumor suppressor Ras-association domain family 6 and induces apoptosis and cell cycle arrest by MDM2 and p53. Cancer Sci. 2018.09; 109 (9): 2767-2780. ( PubMed, DOI )

  10. Shakhawoat Hossain, Hiroaki Iwasa, Aradhan Sarkar, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Yutaka Hata. The RASSF6 Tumor Suppressor Protein Regulates Apoptosis and Cell Cycle Progression via Retinoblastoma Protein. Mol Cell Biol. 2018.08; 38 (17): ( PubMed, DOI )

  11. Junichi Maruyama, Kazutoshi Inami, Fumiyoshi Michishita, Xinliang Jiang, Hiroaki Iwasa, Kentaro Nakagawa, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Norio Miyamura, Jun Hirayama, Hiroshi Nishina, Daichi Nogawa, Kouhei Yamamoto, Yutaka Hata. Novel YAP1 Activator, Identified by Transcription-Based Functional Screen, Limits Multiple Myeloma Growth. Mol. Cancer Res.. 2018.02; 16 (2): 197-211. ( PubMed, DOI )

  12. Xiaoyin Xu, Hiroaki Iwasa, Shakhawoat Hossain, Aradhan Sarkar, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Yutaka Hata. BCL-XL binds and antagonizes RASSF6 tumor suppressor to suppress p53 expression. Genes Cells. 2017.12; 22 (12): 993-1003. ( PubMed, DOI )

  13. Sarkar A, Iwasa H, Hossain S, Xu X, Sawada T, Shimizu T, Maruyama J, Arimoto-Matsuzaki K, Hata Y.. Domain analysis of Ras-association domain family member 6 upon interaction with MDM2. FEBS Letters. 2017.01; 591 (2): 260-272. ( DOI )

  14. Arimoto-Matsuzaki K, Saito H, Takekawa M.. TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis. Nature Communications. 2016.01;

  15. Ohshima D, Arimoto-Matsuzaki K, Tomida T, Takekawa M, Ichikawa K.. Spatio-temporal Dynamics and Mechanisms of Stress Granule Assembly. PLoS Computational Biology. 2015.06; 11 (6):

  16. Arimoto K, Fukuda H, Imajoh-Ohmi S, Saito H, Takekawa M.. Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways. Nature Cell Biology. 2008.11; 10 (11): 1324-1332.

▼display all