Murwanti Retno, Denda-Nagai Kaori, Sugiura Daisuke, Mogushi Kaoru, Gendler Sandra J, Irimura Tatsuro. Prevention of Inflammation-Driven Colon Carcinogenesis in Human MUC1 Transgenic Mice by Vaccination with MUC1 DNA and Dendritic Cells. Cancers (Basel). 2023.03; 15 (6): ( PubMed, DOI )

Katsuda T, Sato N, Mogushi K, Hase T, Muramatsu M. Sub-GOFA: A tool for Sub-Gene Ontology function analysis in clonal mosaicism using semantic (logical) similarity. Bioinformation. 2022; 18 (1): 53-60. ( PubMed, DOI )

Okazaki Misato, Mogushi Kaoru, Denda-Nagai Kaori, Fujihira Haruhiko, Noji Miki, Ishii-Schrade Katrin, Sakata-Matsuzawa Madoka, Nakai Katsuya, Horimoto Yoshiya, Saito Mitsue, Irimura Tatsuro. Biological and Clinicopathological Implications of Beta-3-N-acetylglucosaminyltransferase 8 in Triple-negative Breast Cancer. Anticancer Res. 2021.02; 41 (2): 845-858. ( PubMed, DOI )

Murakami Fumi, Tsuboi Yumi, Takahashi Yuka, Horimoto Yoshiya, Mogushi Kaoru, Ito Takeshi, Emi Mitsuru, Matsubara Daisuke, Shibata Tatsuhiro, Saito Mitsue, Murakami Yoshinori. Short somatic alterations at the site of copy number variation in breast cancer. Cancer Sci. 2021.01; 112 (1): 444-453. ( PubMed, DOI )

Takakuwa Kazuya, Mogushi Kaoru, Han Min, Fujii Tomoaki, Hosoya Masaki, Yamanami Arina, Akita Tomomi, Yamashita Chikamasa, Hayashida Tetsu, Kato Shunsuke, Yamaguchi Shigeo. A novel diagnostic system to evaluate epidermal growth factor receptor impact as a prognostic and therapeutic indicator for lung adenocarcinoma. Sci Rep. 2020.04; 10 (1): 6214. ( PubMed, DOI )

Nakayama S, Shimonaka S, Elahi M, Nishioka K, Oji Y, Matsumoto SE, Li Y, Yoshino H, Mogushi K, Hatano T, Sato T, Ikura T, Ito N, Motoi Y, Hattori N. Tau aggregation and seeding analyses of two novel MAPT variants found in patients with motor neuron disease and progressive parkinsonism. Neurobiology of aging. 2019.12; 84 240.e13-240.e22. ( PubMed, DOI )

Horimoto Yoshiya, Terao Takako, Tsutsumi Yuko, Tanabe Masahiko, Mogushi Kaoru, Hlaing May Thinzar, Sasaki Ritsuko, Saeki Harumi, Okazaki Misato, Sonoue Hiroshi, Arakawa Atsushi, Saito Mitsue. Estrogen Receptor-positive Ductal Carcinoma In Situ Frequently Overexpresses HER2 Protein Without Gene Amplification. Am J Surg Pathol. 2019.09; 43 (9): 1221-1228. ( PubMed, DOI )

Nakazato K, Mogushi K, Kayamori K, Tsuchiya M, Takahashi KI, Sumino J, Michi Y, Yoda T, Uzawa N. Glucose metabolism changes during the development and progression of oral tongue squamous cell carcinomas. Oncology letters. 2019.08; 18 (2): 1372-1380. ( PubMed, DOI )

Matsumura Yuko, Ito Yasuhiko, Mezawa Yoshihiro, Sulidan Kaidiliayi, Daigo Yataro, Hiraga Toru, Mogushi Kaoru, Wali Nadila, Suzuki Hiromu, Itoh Takumi, Miyagi Yohei, Yokose Tomoyuki, Shimizu Satoru, Takano Atsushi, Terao Yasuhisa, Saeki Harumi, Ozawa Masayuki, Abe Masaaki, Takeda Satoru, Okumura Ko, Habu Sonoko, Hino Okio, Takeda Kazuyoshi, Hamada Michiaki, Orimo Akira. Stromal fibroblasts induce metastatic tumor cell clusters via epithelial-mesenchymal plasticity. Life Sci Alliance. 2019.08; 2 (4): ( PubMed, DOI )

Subat S, Mogushi K, Yasen M, Kohda T, Ishikawa Y, Tanaka H. Identification of genes and pathways, including the CXCL2 axis, altered by DNA methylation in hepatocellular carcinoma. Journal of cancer research and clinical oncology. 2019.03; 145 (3): 675-684. ( PubMed, DOI )

Borna Nurun Nahar, Kishita Yoshihito, Kohda Masakazu, Lim Sze Chern, Shimura Masaru, Wu Yibo, Mogushi Kaoru, Yatsuka Yukiko, Harashima Hiroko, Hisatomi Yuichiro, Fushimi Takuya, Ichimoto Keiko, Murayama Kei, Ohtake Akira, Okazaki Yasushi. Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome. Neurogenetics. 2019.03; 20 (1): 9-25. ( PubMed, DOI )

Shimada S, Mogushi K, Akiyama Y, Furuyama T, Watanabe S, Ogura T, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Arii S, Tanabe M, Wands JR, Tanaka S. Comprehensive molecular and immunological characterization of hepatocellular carcinoma. EBioMedicine. 2019.02; 40 457-470. ( PubMed, DOI )

Sugizaki Toshifumi, Tanaka Ken-Ichiro, Asano Teita, Kobayashi Daisuke, Hino Yuuki, Takafuji Ayaka, Shimoda Mikako, Mogushi Kaoru, Kawahara Masahiro, Mizushima Tohru. Idebenone has preventative and therapeutic effects on pulmonary fibrosis via preferential suppression of fibroblast activity. Cell Death Discov. 2019; 5 146. ( PubMed, DOI )

Sunakawa Yu, Mogushi Kaoru, Lenz Heinz-Josef, Zhang Wu, Tsuji Akihito, Takahashi Takehiro, Denda Tadamichi, Shimada Ken, Kochi Mitsugu, Nakamura Masato, Kotaka Masahito, Segawa Yoshihiko, Tanioka Hiroaki, Negoro Yuji, Moran Miriana, Astrow Stephanie H, Hsiang Jack, Stephens Craig, Fujii Masashi, Ichikawa Wataru. Tumor Sidedness and Enriched Gene Groups for Efficacy of First-line Cetuximab Treatment in Metastatic Colorectal Cancer. Mol Cancer Ther. 2018.12; 17 (12): 2788-2795. ( PubMed, DOI )

Yoshino Hiroyo, Nishioka Kenya, Li Yuanzhe, Oji Yutaka, Oyama Genko, Hatano Taku, Machida Yutaka, Shimo Yasushi, Hayashida Arisa, Ikeda Aya, Mogushi Kaoru, Shibagaki Yasuro, Hosaka Ai, Iwanaga Hiroshi, Fujitake Junko, Ohi Takekazu, Miyazaki Daigo, Sekijima Yoshiki, Oki Mitsuaki, Kusaka Hirofumi, Fujimoto Ken-Ichi, Ugawa Yoshikazu, Funayama Manabu, Hattori Nobutaka. GCH1 mutations in dopa-responsive dystonia and Parkinson's disease. J Neurol. 2018.08; 265 (8): 1860-1870. ( PubMed, DOI )

Hayashi Takuo, Takamochi Kazuya, Yanai Yuka, Mitani Keiko, Tomita Hisashi, Mogushi Kaoru, Suehara Yoshiyuki, Takahashi Fumiyuki, Suzuki Kenji, Saito Tsuyoshi, Yao Takashi. Non-small cell lung carcinoma with diffuse coexpression of thyroid transcription factor-1 and ΔNp63/p40. Hum Pathol. 2018.08; 78 177-181. ( PubMed, DOI )

Ueda H, Akiyama Y, Shimada S, Mogushi K, Serizawa M, Matsumura S, Mitsunori Y, Aihara A, Ban D, Ochiai T, Kudo A, Tanabe M, Tanaka S.. Tumor suppressor functions of DAXX through histone H3.3/H3K9me3 pathway in pancreatic NETs. Endocr Relat Cancer. 2018.06; 25 (6): 619-631.

Ueda H, Akiyama Y, Shimada S, Mogushi K, Serizawa M, Matsumura S, Mitsunori Y, Aihara A, Ban D, Ochiai T, Kudo A, Tanabe M, Tanaka S. Tumor suppressor functions of DAXX through histone H3.3/H3K9me3 pathway in pancreatic NETs. Endocrine-related cancer. 2018.06; 25 (6): 619-631. ( PubMed, DOI )

Suehara Yoshiyuki, Akaike Keisuke, Mukaihara Kenta, Kurisaki-Arakawa Aiko, Kubota Daisuke, Okubo Taketo, Mitomi Hiroyuki, Mitani Keiko, Takahashi Michiko, Toda-Ishii Midori, Kim Youngji, Tanabe Yu, Takagi Tatsuya, Hayashi Takuo, Mogushi Kaoru, Kaneko Kazuo, Yao Takashi, Saito Tsuyoshi. KCTD12 is negatively regulated by Kit in gastrointestinal stromal tumors. Oncotarget. 2018.06; 9 (43): 27016-27026. ( PubMed, DOI )

Mikasa Michitaka, Kanai Kazuaki, Li Yuanzhe, Yoshino Hiroyo, Mogushi Kaoru, Hayashida Arisa, Ikeda Aya, Kawajiri Sumihiro, Okuma Yasuyuki, Kashihara Kenichi, Sato Tatsuya, Kondo Hiroshi, Funayama Manabu, Nishioka Kenya, Hattori Nobutaka. COQ2 variants in Parkinson's disease and multiple system atrophy. J Neural Transm (Vienna). 2018.06; 125 (6): 937-944. ( PubMed, DOI )

Chiyonobu N, Shimada S, Akiyama Y, Mogushi K, Itoh M, Akahoshi K, Matsumura S, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Arii S, Suganami T, Yamaoka S, Ogawa Y, Tanabe M, Tanaka S. Fatty Acid Binding Protein 4 (FABP4) Overexpression in Intratumoral Hepatic Stellate Cells within Hepatocellular Carcinoma with Metabolic Risk Factors. The American journal of pathology. 2018.05; 188 (5): 1213-1224. ( PubMed, DOI )

Horimoto Yoshiya, Tanabe Masahiko, Kazuno Saiko, Miura Yoshiki, Mogushi Kaoru, Sonoue Hiroshi, Arakawa Atsushi, Kajino Kazunori, Kobayashi Toshiyuki, Saito Mitsue. Elucidation of inhibitory effects on metastatic sentinel lymph nodes of breast cancer during One-Step Nucleic Acid Amplification. Sci Rep. 2018.05; 8 (1): 7563. ( PubMed, DOI )

Shimada S, Akiyama Y, Mogushi K, Ishigami-Yuasa M, Kagechika H, Nagasaki H, Fukamachi H, Yuasa Y, Tanaka S. Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models. British journal of cancer. 2018.04; 118 (7): 972-984. ( PubMed, DOI )

Yamaguchi Shigeo, Takahashi Shin, Mogushi Kaoru, Izumi Yuki, Nozaki Yumi, Nomizu Tadashi, Kakugawa Yoichiro, Ishida Takanori, Ohuchi Noriaki, Ishioka Chikashi, Kato Shunsuke. Molecular and clinical features of the TP53 signature gene expression profile in early-stage breast cancer. Oncotarget. 2018.03; 9 (18): 14193-14206. ( PubMed, DOI )

Yoshida Emiko, Terao Yasuhisa, Hayashi Noriko, Mogushi Kaoru, Arakawa Atsushi, Tanaka Yuji, Ito Yosuke, Ohmiya Hiroko, Hayashizaki Yoshihide, Takeda Satoru, Itoh Masayoshi, Kawaji Hideya. Promoter-level transcriptome in primary lesions of endometrial cancer identified biomarkers associated with lymph node metastasis. Sci Rep. 2017.10; 7 (1): 14160. ( PubMed, DOI )

Uomori Toshitaka, Horimoto Yoshiya, Mogushi Kaoru, Matsuoka Joe, Saito Mitsue. Relationship between alcohol metabolism and chemotherapy-induced emetic events in breast cancer patients. Breast Cancer. 2017.09; 24 (5): 702-707. ( PubMed, DOI )

Ohata Y, Shimada S, Akiyama Y, Mogushi K, Ito H, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Tanabe M, Tanaka S. . Acquired resistance with epigenetic alterations under long-term anti-angiogenic therapy for hepatocellular carcinoma Molecular Cancer Therapeutics. 2017.06; 16 (6): 1155-1165. ( DOI )

Ohata Y, Shimada S, Akiyama Y, Mogushi K, Nakao K, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Arii S, Tanabe M, Tanaka S. Acquired Resistance with Epigenetic Alterations Under Long-Term Antiangiogenic Therapy for Hepatocellular Carcinoma. Molecular cancer therapeutics. 2017.06; 16 (6): 1155-1165. ( PubMed, DOI )

Oba A, Shimada S, Akiyama Y, Nishikawaji T, Mogushi K, Ito H, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Asahara H, Kaida A, Miura M, Tanabe M, Tanaka S. ARID2 modulates DNA damage response in human hepatocellular carcinoma cells. Journal of hepatology. 2017.05; 66 (5): 942-951. ( PubMed, DOI )

Satoh Mamoru, Takano Shigetsugu, Sogawa Kazuyuki, Noda Kenta, Yoshitomi Hideyuki, Ishibashi Masumi, Mogushi Kaoru, Takizawa Hirotaka, Otsuka Masayuki, Shimizu Hiroaki, Miyazaki Masaru, Nomura Fumio. Immune-complex level of cofilin-1 in sera is associated with cancer progression and poor prognosis in pancreatic cancer. Cancer Sci. 2017.04; 108 (4): 795-803. ( PubMed, DOI )

Ishizawa Jo, Sugihara Eiji, Kuninaka Shinji, Mogushi Kaoru, Kojima Kensuke, Benton Christopher B, Zhao Ran, Chachad Dhruv, Hashimoto Norisato, Jacamo Rodrigo O, Qiu Yihua, Yoo Suk Young, Okamoto Shinichiro, Andreeff Michael, Kornblau Steven M, Saya Hideyuki. FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B-cell acute leukemia. Blood. 2017.04; 129 (14): 1958-1968. ( PubMed, DOI )

Jotatsu Takanobu, Yagishita Shigehiro, Tajima Ken, Takahashi Fumiyuki, Mogushi Kaoru, Hidayat Moulid, Wirawan Aditya, Ko Ryo, Kanemaru Ryota, Shimada Naoko, Mitani Keiko, Saito Tsuyoshi, Takamochi Kazuya, Suzuki Kenji, Kohsaka Shinji, Kojima Shinya, Mukae Hiroshi, Yatera Kazuhiro, Takahashi Kazuhisa. LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer. Biochem Biophys Rep. 2017.03; 9 86-94. ( PubMed, DOI )

Tabe Yoko, Yamamoto Shinichi, Saitoh Kaori, Sekihara Kazumasa, Monma Norikazu, Ikeo Kazuho, Mogushi Kaoru, Shikami Masato, Ruvolo Vivian, Ishizawa Jo, Hail Numsen Jr, Kazuno Saiko, Igarashi Mamoru, Matsushita Hiromichi, Yamanaka Yasunari, Arai Hajime, Nagaoka Isao, Miida Takashi, Hayashizaki Yoshihide, Konopleva Marina, Andreeff Michael. Bone Marrow Adipocytes Facilitate Fatty Acid Oxidation Activating AMPK and a Transcriptional Network Supporting Survival of Acute Monocytic Leukemia Cells. Cancer Res. 2017.03; 77 (6): 1453-1464. ( PubMed, DOI )

Iwata N, Ishikawa T, Okazaki S, Mogushi K, Baba H, Ishiguro M, Kobayashi H, Tanaka H, Kawano T, Sugihara K, Uetake H. Clinical Significance of Methylation and Reduced Expression of the Quaking Gene in Colorectal Cancer. Anticancer research. 2017.02; 37 (2): 489-498. ( PubMed, DOI )

Mukaihara K, Tanabe Y, Kubota D, Akaike K, Hayashi T, Mogushi K, Hosoya M, Sato S, Kobayashi E, Okubo T, Kim Y, Kohsaka S, Saito T, Kaneko K, Suehara Y. Cabozantinib and dastinib exert anti-tumor activity in alveolar soft part sarcoma. PloS one. 2017; 12 (9): e0185321. ( PubMed, DOI )

Takamochi Kazuya, Mogushi Kaoru, Kawaji Hideya, Imashimizu Kota, Fukui Mariko, Oh Shiaki, Itoh Masayoshi, Hayashizaki Yoshihide, Ko Weijey, Akeboshi Masao, Suzuki Kenji. Correlation of EGFR or KRAS mutation status with 18F-FDG uptake on PET-CT scan in lung adenocarcinoma. PLoS One. 2017; 12 (4): e0175622. ( PubMed, DOI )

Morita Takuma, Uzawa Narikazu, Mogushi Kaoru, Sumino Jun, Michikawa Chieko, Takahashi Ken-Ichiro, Myo Kunihiro, Izumo Toshiyuki, Harada Kiyoshi. Characterizing Genetic Transitions of Copy Number Alterations and Allelic Imbalances in Oral Tongue Carcinoma Metastasis. Genes Chromosomes Cancer. 2016.12; 55 (12): 975-986. ( PubMed, DOI )

Toda-Ishii Midori, Akaike Keisuke, Suehara Yoshiyuki, Mukaihara Kenta, Kubota Daisuke, Kohsaka Shinji, Okubo Taketo, Mitani Keiko, Mogushi Kaoru, Takagi Tatsuya, Kaneko Kazuo, Yao Takashi, Saito Tsuyoshi. Clinicopathological effects of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors. Mod Pathol. 2016.11; 29 (11): 1424-1432. ( PubMed, DOI )

Akahoshi K, Tanaka S, Mogushi K, Shimada S, Matsumura S, Akiyama Y, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Arii S, Tanabe M.. Expression of connective tissue growth factor in the livers of non-viral hepatocellular carcinoma patients with metabolic risk factors. J Gastroenterol. . 2016.09; 51 (9): 910-922.

Takamochi Kazuya, Ohmiya Hiroko, Itoh Masayoshi, Mogushi Kaoru, Saito Tsuyoshi, Hara Kieko, Mitani Keiko, Kogo Yasushi, Yamanaka Yasunari, Kawai Jun, Hayashizaki Yoshihide, Oh Shiaki, Suzuki Kenji, Kawaji Hideya. Novel biomarkers that assist in accurate discrimination of squamous cell carcinoma from adenocarcinoma of the lung. BMC Cancer. 2016.09; 16 (1): 760. ( PubMed, DOI )

Akahoshi Keiichi, Tanaka Shinji, Mogushi Kaoru, Shimada Shu, Matsumura Satoshi, Akiyama Yoshimitsu, Aihara Arihiro, Mitsunori Yusuke, Ban Daisuke, Ochiai Takanori, Kudo Atsushi, Arii Shigeki, Tanabe Minoru. Expression of connective tissue growth factor in the livers of non-viral hepatocellular carcinoma patients with metabolic risk factors. J Gastroenterol. 2016.09; 51 (9): 910-922. ( PubMed, DOI )

Shimizu Chikako, Mogushi Kaoru, Morioka Masaki Suimye, Yamamoto Harukaze, Tamura Kenji, Fujiwara Yasuhiro, Tanaka Hiroshi. Fc-Gamma receptor polymorphism and gene expression of peripheral blood mononuclear cells in patients with HER2-positive metastatic breast cancer receiving single-agent trastuzumab. Breast Cancer. 2016.07; 23 (4): 624-632. ( PubMed, DOI )

Masuda Taiki, Ishikawa Toshiaki, Mogushi Kaoru, Okazaki Satoshi, Ishiguro Megumi, Iida Satoru, Mizushima Hiroshi, Tanaka Hiroshi, Uetake Hiroyuki, Sugihara Kenichi. Overexpression of the S100A2 protein as a prognostic marker for patients with stage II and III colorectal cancer. Int J Oncol. 2016.03; 48 (3): 975-982. ( PubMed, DOI )

Katsuta E, Tanaka S, Mogushi K, Shimada S, Akiyama Y, Aihara A, Matsumura S, Mitsunori Y, Ban D, Ochiai T, Kudo A, Fukamachi H, Tanaka H, Nakayama K, Arii S, Tanabe M.. CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells. Int J Oncol. . 2016.02; 48 (2): 657-669.

Katsuta Eriko, Tanaka Shinji, Mogushi Kaoru, Shimada Shu, Akiyama Yoshimitsu, Aihara Arihiro, Matsumura Satoshi, Mitsunori Yusuke, Ban Daisuke, Ochiai Takanori, Kudo Atsushi, Fukamachi Hiroshi, Tanaka Hiroshi, Nakayama Koh, Arii Shigeki, Tanabe Minoru. CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells. Int J Oncol. 2016.02; 48 (2): 657-669. ( PubMed, DOI )

Takahashi Hidenori, Ishikawa Toshiaki, Ishiguro Megumi, Okazaki Satoshi, Mogushi Kaoru, Kobayashi Hirotoshi, Iida Satoru, Mizushima Hiroshi, Tanaka Hiroshi, Uetake Hiroyuki, Sugihara Kenichi. Prognostic significance of Traf2- and Nck- interacting kinase (TNIK) in colorectal cancer. BMC Cancer. 2015.10; 15 794. ( PubMed, DOI )

Miura Tomoya, Ban Daisuke, Tanaka Shinji, Mogushi Kaoru, Kudo Atsushi, Matsumura Satoshi, Mitsunori Yusuke, Ochiai Takanori, Tanaka Hiroshi, Tanabe Minoru. Distinct clinicopathological phenotype of hepatocellular carcinoma with ethoxybenzyl-magnetic resonance imaging hyperintensity: association with gene expression signature. Am J Surg. 2015.09; 210 (3): 561-569. ( PubMed, DOI )

Aikawa Tomonori, Mogushi Kaoru, Iijima-Tsutsui Kumiko, Ishikawa Kinya, Sakurai Miyano, Tanaka Hiroshi, Mizusawa Hidehiro, Watase Kei. Loss of MyD88 alters neuroinflammatory response and attenuates early Purkinje cell loss in a spinocerebellar ataxia type 6 mouse model. Hum Mol Genet. 2015.09; 24 (17): 4780-4791. ( PubMed, DOI )

Funayama Manabu, Ohe Kenji, Amo Taku, Furuya Norihiko, Yamaguchi Junji, Saiki Shinji, Li Yuanzhe, Ogaki Kotaro, Ando Maya, Yoshino Hiroyo, Tomiyama Hiroyuki, Nishioka Kenya, Hasegawa Kazuko, Saiki Hidemoto, Satake Wataru, Mogushi Kaoru, Sasaki Ryogen, Kokubo Yasumasa, Kuzuhara Shigeki, Toda Tatsushi, Mizuno Yoshikuni, Uchiyama Yasuo, Ohno Kinji, Hattori Nobutaka. CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study. Lancet Neurol. 2015.03; 14 (3): 274-282. ( PubMed, DOI )

Moriya Yujiro, Uzawa Narikazu, Morita Takuma, Mogushi Kaoru, Miyaguchi Ken, Takahashi Ken-Ichiro, Michikawa Chieko, Sumino Jun, Tanaka Hiroshi, Harada Kiyoshi. The high-temperature requirement factor A3 (HtrA3) is associated with acquisition of the invasive phenotype in oral squamous cell carcinoma cells. Oral Oncol. 2015.01; 51 (1): 84-89. ( PubMed, DOI )

Yui Daishi, Nishida Yoichiro, Nishina Tomoko, Mogushi Kaoru, Tajiri Mio, Ishibashi Satoru, Ajioka Itsuki, Ishikawa Kinya, Mizusawa Hidehiro, Murayama Shigeo, Yokota Takanori. Enhanced Phospholipase A2 Group 3 Expression by Oxidative Stress Decreases the Insulin-Degrading Enzyme. PLoS One. 2015; 10 (12): e0143518. ( PubMed, DOI )

Katsuta Eriko, Tanaka Shinji, Mogushi Kaoru, Matsumura Satoshi, Ban Daisuke, Ochiai Takanori, Irie Takumi, Kudo Atsushi, Nakamura Noriaki, Tanaka Hiroshi, Tanabe Minoru, Arii Shigeki. Age-related clinicopathologic and molecular features of patients receiving curative hepatectomy for hepatocellular carcinoma. Am J Surg. 2014.09; 208 (3): 450-456. ( PubMed, DOI )

Kudo Atsushi, Mogushi Kaoru, Takayama Tadatoshi, Matsumura Satoshi, Ban Daisuke, Irie Takumi, Ochiai Takanori, Nakamura Noriaki, Tanaka Hiroshi, Anzai Naohiko, Sakamoto Michiie, Tanaka Shinji, Arii Shigeki. Mitochondrial metabolism in the noncancerous liver determine the occurrence of hepatocellular carcinoma: a prospective study. J Gastroenterol. 2014.03; 49 (3): 502-510. ( PubMed, DOI )

Tsubota Akihito, Mogushi Kaoru, Aizaki Hideki, Miyaguchi Ken, Nagatsuma Keisuke, Matsudaira Hiroshi, Kushida Tatsuya, Furihata Tomomi, Tanaka Hiroshi, Matsuura Tomokazu. Involvement of MAP3K8 and miR-17-5p in poor virologic response to interferon-based combination therapy for chronic hepatitis C. PLoS One. 2014; 9 (5): e97078. ( PubMed, DOI )

Muramatsu Shunsuke, Tanaka Shinji, Mogushi Kaoru, Adikrisna Rama, Aihara Arihiro, Ban Daisuke, Ochiai Takanori, Irie Takumi, Kudo Atsushi, Nakamura Noriaki, Nakayama Koh, Tanaka Hiroshi, Yamaoka Shoji, Arii Shigeki. Visualization of stem cell features in human hepatocellular carcinoma reveals in vivo significance of tumor-host interaction and clinical course. Hepatology. 2013.07; 58 (1): 218-228. ( PubMed, DOI )

Kikuchi Akifumi, Ishikawa Toshiaki, Mogushi Kaoru, Ishiguro Megumi, Iida Satoru, Mizushima Hiroshi, Uetake Hiroyuki, Tanaka Hiroshi, Sugihara Kenichi. Identification of NUCKS1 as a colorectal cancer prognostic marker through integrated expression and copy number analysis. Int J Cancer. 2013.05; 132 (10): 2295-2302. ( PubMed, DOI )

Sato Kota, Tanaka Shinji, Mitsunori Yusuke, Mogushi Kaoru, Yasen Mahmut, Aihara Arihiro, Ban Daisuke, Ochiai Takanori, Irie Takumi, Kudo Atsushi, Nakamura Noriaki, Tanaka Hiroshi, Arii Shigeki. Contrast-enhanced intraoperative ultrasonography for vascular imaging of hepatocellular carcinoma: clinical and biological significance. Hepatology. 2013.04; 57 (4): 1436-1447. ( PubMed, DOI )

Obulhasim Gulanbar, Yasen Mahmut, Kajino Kazunori, Mogushi Kaoru, Tanaka Shinji, Mizushima Hiroshi, Tanaka Hiroshi, Arii Shigeki, Hino Okio. Up-regulation of dbpA mRNA in hepatocellular carcinoma associated with metabolic syndrome. Hepatol Int. 2013.03; 7 (1): 215-225. ( PubMed, DOI )

Sumino Jun, Uzawa Narikazu, Okada Norihiko, Miyaguchi Ken, Mogushi Kaoru, Takahashi Ken-Ichiro, Sato Hiroaki, Michikawa Chieko, Nakata Yoshimi, Tanaka Hiroshi, Amagasa Teruo. Gene expression changes in initiation and progression of oral squamous cell carcinomas revealed by laser microdissection and oligonucleotide microarray analysis. Int J Cancer. 2013.02; 132 (3): 540-548. ( PubMed, DOI )

Mayinuer Abudureheman, Yasen Mahmut, Mogushi Kaoru, Obulhasim Gulanbar, Xieraili Maimaiti, Aihara Arihiro, Tanaka Shinji, Mizushima Hiroshi, Tanaka Hiroshi, Arii Shigeki. Upregulation of protein tyrosine phosphatase type IVA member 3 (PTP4A3/PRL-3) is associated with tumor differentiation and a poor prognosis in human hepatocellular carcinoma. Ann Surg Oncol. 2013.01; 20 (1): 305-317. ( PubMed, DOI )

Tanaka Ken-Ichiro, Ishihara Tomoaki, Sugizaki Toshifumi, Kobayashi Daisuke, Yamashita Yasunobu, Tahara Kayoko, Yamakawa Naoki, Iijima Kumiko, Mogushi Kaoru, Tanaka Hiroshi, Sato Keizo, Suzuki Hidekazu, Mizushima Tohru. Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease. Nat Commun. 2013; 4 2686. ( PubMed, DOI )

Takahashi Makoto, Obayashi Masato, Ishiguro Taro, Sato Nozomu, Niimi Yusuke, Ozaki Kokoro, Mogushi Kaoru, Mahmut Yasen, Tanaka Hiroshi, Tsuruta Fuminori, Dolmetsch Ricardo, Yamada Mitsunori, Takahashi Hitoshi, Kato Takeo, Mori Osamu, Eishi Yoshinobu, Mizusawa Hidehiro, Ishikawa Kinya. Cytoplasmic location of α1A voltage-gated calcium channel C-terminal fragment (Cav2.1-CTF) aggregate is sufficient to cause cell death. PLoS One. 2013; 8 (3): e50121. ( PubMed, DOI )

Mogushi Kaoru, Tanaka Hiroshi. PathAct: a novel method for pathway analysis using gene expression profiles. Bioinformation. 2013; 9 (8): 394-400. ( PubMed, DOI )

Khamas Ahmed, Ishikawa Toshiaki, Mogushi Kaoru, Iida Satoru, Ishiguro Megumi, Tanaka Hiroshi, Uetake Hiroyuki, Sugihara Kenichi. Genome-wide screening for methylation-silenced genes in colorectal cancer. Int J Oncol. 2012.08; 41 (2): 490-496. ( PubMed, DOI )

Xieraili Maimaiti, Yasen Mahmut, Mogushi Kaoru, Obulhasim Gulanbar, Mayinuer Abudureheman, Aihara Arihiro, Tanaka Shinji, Mizushima Hiroshi, Tanaka Hiroshi, Arii Shigeki. Villin 1 is a predictive factor for the recurrence of high serum alpha-fetoprotein-associated hepatocellular carcinoma after hepatectomy. Cancer Sci. 2012.08; 103 (8): 1493-1501. ( PubMed, DOI )

Yae Toshifumi, Tsuchihashi Kenji, Ishimoto Takatsugu, Motohara Takeshi, Yoshikawa Momoko, Yoshida Go J, Wada Takeyuki, Masuko Takashi, Mogushi Kaoru, Tanaka Hiroshi, Osawa Tsuyoshi, Kanki Yasuharu, Minami Takashi, Aburatani Hiroyuki, Ohmura Mitsuyo, Kubo Akiko, Suematsu Makoto, Takahashi Kazuhisa, Saya Hideyuki, Nagano Osamu. Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell. Nat Commun. 2012.06; 3 883. ( PubMed, DOI )

Miyaguchi Ken, Uzawa Narikazu, Mogushi Kaoru, Takahashi Ken-Ichiro, Michikawa Chieko, Nakata Yoshimi, Sumino Jun, Okada Norihiko, Mizushima Hiroshi, Fukuoka Yutaka, Tanaka Hiroshi. Loss of NKX3-1 as a potential marker for an increased risk of occult lymph node metastasis and poor prognosis in oral squamous cell carcinoma. Int J Oncol. 2012.06; 40 (6): 1907-1914. ( PubMed, DOI )

Nomura Fumio, Sogawa Kazuyuki, Noda Kenta, Seimiya Masanori, Matsushita Kazuyuki, Miura Toshihide, Tomonaga Takeshi, Yoshitomi Hideyuki, Imazeki Fumio, Takizawa Hirotaka, Mogushi Kaoru, Miyazaki Masaru, Yokosuka Osamu. Serum anti-Ku86 is a potential biomarker for early detection of hepatitis C virus-related hepatocellular carcinoma. Biochem Biophys Res Commun. 2012.05; 421 (4): 837-843. ( PubMed, DOI )

Yasen Mahmut, Obulhasim Gulanbar, Kajino Kazunori, Mogushi Kaoru, Mizushima Hiroshi, Tanaka Shinji, Tanaka Hiroshi, Hino Okio, Arii Shigeki. DNA binding protein A expression and methylation status in hepatocellular carcinoma and the adjacent tissue. Int J Oncol. 2012.03; 40 (3): 789-797. ( PubMed, DOI )

Shimada Shu, Mimata Ayako, Sekine Masaki, Mogushi Kaoru, Akiyama Yoshimitsu, Fukamachi Hiroshi, Jonkers Jos, Tanaka Hiroshi, Eishi Yoshinobu, Yuasa Yasuhito. Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer. Gut. 2012.03; 61 (3): 344-353. ( PubMed, DOI )

Okazaki Satoshi, Ishikawa Toshiaki, Iida Satoru, Ishiguro Megumi, Kobayashi Hirotoshi, Higuchi Tetsuro, Enomoto Masayuki, Mogushi Kaoru, Mizushima Hiroshi, Tanaka Hiroshi, Uetake Hiroyuki, Sugihara Kenichi. Clinical significance of UNC5B expression in colorectal cancer. Int J Oncol. 2012.01; 40 (1): 209-216. ( PubMed, DOI )

Tanaka Shinji, Mogushi Kaoru, Yasen Mahmut, Ban Daisuke, Noguchi Norio, Irie Takumi, Kudo Atsushi, Nakamura Noriaki, Tanaka Hiroshi, Yamamoto Masakazu, Kokudo Norihiro, Takayama Tadatoshi, Kawasaki Seiji, Sakamoto Michiie, Arii Shigeki. Oxidative stress pathways in noncancerous human liver tissue to predict hepatocellular carcinoma recurrence: a prospective, multicenter study. Hepatology. 2011.10; 54 (4): 1273-1281. ( PubMed, DOI )

Yoshitake Kenichiro, Tanaka Shinji, Mogushi Kaoru, Aihara Arihiro, Murakata Ayano, Matsumura Satoshi, Mitsunori Yusuke, Yasen Mahmut, Ban Daisuke, Noguchi Norio, Irie Takumi, Kudo Atsushi, Nakamura Noriaki, Tanaka Hiroshi, Arii Shigeki. Importin-α1 as a novel prognostic target for hepatocellular carcinoma. Ann Surg Oncol. 2011.07; 18 (7): 2093-2103. ( PubMed, DOI )

Umemura Hiroshi, Togawa Akira, Sogawa Kazuyuki, Satoh Mamoru, Mogushi Kaoru, Nishimura Motoi, Matsushita Kazuyuki, Tanaka Hiroshi, Takizawa Hirotaka, Kodera Yoshio, Nomura Fumio. Identification of a high molecular weight kininogen fragment as a marker for early gastric cancer by serum proteome analysis. J Gastroenterol. 2011.05; 46 (5): 577-585. ( PubMed, DOI )

Tsukamoto Shunsuke, Ishikawa Toshiaki, Iida Satoru, Ishiguro Megumi, Mogushi Kaoru, Mizushima Hiroshi, Uetake Hiroyuki, Tanaka Hiroshi, Sugihara Kenichi. Clinical significance of osteoprotegerin expression in human colorectal cancer. Clin Cancer Res. 2011.04; 17 (8): 2444-2450. ( PubMed, DOI )

Murakata Ayano, Tanaka Shinji, Mogushi Kaoru, Yasen Mahmut, Noguchi Norio, Irie Takumi, Kudo Atsushi, Nakamura Noriaki, Tanaka Hiroshi, Arii Shigeki. Gene expression signature of the gross morphology in hepatocellular carcinoma. Ann Surg. 2011.01; 253 (1): 94-100. ( PubMed, DOI )

Shimokawa Kazuro, Mogushi Kaoru, Shoji Satoshi, Hiraishi Atsuko, Ido Keisuke, Mizushima Hiroshi, Tanaka Hiroshi. iCOD: an integrated clinical omics database based on the systems-pathology view of disease. BMC Genomics. 2010.12; 11 Suppl 4 (Suppl 4): S19. ( PubMed, DOI )

Matsuyama Takatoshi, Ishikawa Toshiaki, Mogushi Kaoru, Yoshida Tsuyoshi, Iida Satoru, Uetake Hiroyuki, Mizushima Hiroshi, Tanaka Hiroshi, Sugihara Kenichi. MUC12 mRNA expression is an independent marker of prognosis in stage II and stage III colorectal cancer. Int J Cancer. 2010.11; 127 (10): 2292-2299. ( PubMed, DOI )

Nakahara Izumi, Miyamoto Mamiko, Shibata Tatsuhiro, Akashi-Tanaka Sadako, Kinoshita Takayuki, Mogushi Kaoru, Oda Kohtaro, Ueno Masaya, Takakura Nobuyuki, Mizushima Hiroshi, Tanaka Hiroshi, Ohta Tsutomu. Up-regulation of PSF1 promotes the growth of breast cancer cells. Genes Cells. 2010.10; 15 (10): 1015-1024. ( PubMed, DOI )

Shimizu Sayaka, Iida Satoru, Ishiguro Megumi, Uetake Hiroyuki, Ishikawa Toshiaki, Takagi Yoko, Kobayashi Hirotoshi, Higuchi Tetsuro, Enomoto Masayuki, Mogushi Kaoru, Mizushima Hiroshi, Tanaka Hiroshi, Sugihara Kenichi. Methylated BNIP3 gene in colorectal cancer prognosis. Oncol Lett. 2010.09; 1 (5): 865-872. ( PubMed, DOI )

Yoshida Tsuyoshi, Kobayashi Takumi, Itoda Masaya, Muto Taika, Miyaguchi Ken, Mogushi Kaoru, Shoji Satoshi, Shimokawa Kazuro, Iida Satoru, Uetake Hiroyuki, Ishikawa Toshiaki, Sugihara Kenichi, Mizushima Hiroshi, Tanaka Hiroshi. Clinical omics analysis of colorectal cancer incorporating copy number aberrations and gene expression data. Cancer Inform. 2010.07; 9 147-161. ( PubMed, DOI )

Nakagawa Mina, Sakamoto Naoya, Ueyama Mayumi, Mogushi Kaoru, Nagaie Satoshi, Itsui Yasuhiro, Azuma Seishin, Kakinuma Sei, Tanaka Hiroshi, Enomoto Nobuyuki, Watanabe Mamoru. Mutations in the interferon sensitivity determining region and virological response to combination therapy with pegylated-interferon alpha 2b plus ribavirin in patients with chronic hepatitis C-1b infection. J Gastroenterol. 2010.06; 45 (6): 656-665. ( PubMed, DOI )

Nishimura-Sakurai Yuki, Sakamoto Naoya, Mogushi Kaoru, Nagaie Satoshi, Nakagawa Mina, Itsui Yasuhiro, Tasaka-Fujita Megumi, Onuki-Karakama Yuko, Suda Goki, Mishima Kako, Yamamoto Machi, Ueyama Mayumi, Funaoka Yusuke, Watanabe Takako, Azuma Seishin, Sekine-Osajima Yuko, Kakinuma Sei, Tsuchiya Kiichiro, Enomoto Nobuyuki, Tanaka Hiroshi, Watanabe Mamoru. Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells. J Gastroenterol. 2010.05; 45 (5): 523-536. ( PubMed, DOI )

Tsubota Akihito, Matsumoto Kenji, Mogushi Kaoru, Nariai Koichi, Namiki Yoshihisa, Hoshina Sadayori, Hano Hiroshi, Tanaka Hiroshi, Saito Hirohisa, Tada Norio. IQGAP1 and vimentin are key regulator genes in naturally occurring hepatotumorigenesis induced by oxidative stress. Carcinogenesis. 2010.03; 31 (3): 504-511. ( PubMed, DOI )

Tanaka Shinji, Mogushi Kaoru, Yasen Mahmut, Noguchi Norio, Kudo Atsushi, Nakamura Noriaki, Ito Koji, Miki Yoshio, Inazawa Johji, Tanaka Hiroshi, Arii Shigeki. Gene-expression phenotypes for vascular invasiveness of hepatocellular carcinomas. Surgery. 2010.03; 147 (3): 405-414. ( PubMed, DOI )

Tanaka Shinji, Mogushi Kaoru, Yasen Mahmut, Noguchi Norio, Kudo Atsushi, Kurokawa Toshiaki, Nakamura Noriaki, Inazawa Johji, Tanaka Hiroshi, Arii Shigeki. Surgical contribution to recurrence-free survival in patients with macrovascular-invasion-negative hepatocellular carcinoma. J Am Coll Surg. 2009.03; 208 (3): 368-374. ( PubMed, DOI )

Yasen Mahmut, Mizushima Hiroshi, Mogushi Kaoru, Obulhasim Gulanbar, Miyaguchi Ken, Inoue Kazuhiko, Nakahara Izumi, Ohta Tsutomu, Aihara Arihiro, Tanaka Shinji, Arii Shigeki, Tanaka Hiroshi. Expression of Aurora B and alternative variant forms in hepatocellular carcinoma and adjacent tissue. Cancer Sci. 2009.03; 100 (3): 472-480. ( PubMed, DOI )

Watanabe Hiroshi, Mogushi Kaoru, Miura Masahiko, Yoshimura Ryo-Ichi, Kurabayashi Tohru, Shibuya Hitoshi, Tanaka Hiroshi, Noda Shuhei, Iwakawa Mayumi, Imai Takashi. Prediction of lymphatic metastasis based on gene expression profile analysis after brachytherapy for early-stage oral tongue carcinoma. Radiother Oncol. 2008.05; 87 (2): 237-242. ( PubMed, DOI )