Personnel Information

写真a

SAITO Natsumi


Job title

Visiting Lecturer
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Graduating School 【 display / non-display 】

  • Tokyo Medical and Dental University, Faculty of Dentistry, 2017.03, Graduated

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Campus Career 【 display / non-display 】

  • 2014.11
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    2016.04
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Staff Assistant
  • 2017.10
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    2018.03
    Tokyo Medical and Dental University， (Old Organization)Dental Hospital， Trainee Resident
  • 2018.04
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    2022.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Bio-Matrix， Department of Periodontology， Graduate Student
  • 2018.04
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    2022.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Periodontology， Graduate Student
  • 2024.04
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    2024.09
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Clinical Dentistry， Department of Conservative Dentistry， Periodontics， Project Assistant Professor
  • 2024.10
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    2025.06
    Institute of Science Tokyo， -， Institute of Science Tokyo Hospital， Department of Conservative Dentistry， Periodontics， Project Assistant Professor
  • 2025.07
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    Now
    Institute of Science Tokyo， -， Institute of Science Tokyo Hospital， Department of Conservative Dentistry， Periodontics， Visiting Lecturer

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Research Areas 【 display / non-display 】

  • Conservative dentistry

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Published Papers & Misc 【 display / non-display 】

  1. Natsumi Saito, Risako Mikami, Koji Mizutani, Norio Aoyama, Takanori Matsuura, Tomonari Suda, Kohei Takeda, Jun Aida, Yuichi Izumi, Takanori Iwata. Income-related inequalities in the association of obesity and periodontal disease: a register-based cross-sectional analysis in the Tokyo metropolitan districts. Clin Oral Investigations. 2025.11; 29 (12): 570. ( PubMed, DOI )

  2. Sakaniwa, E; Mikami, R; Mizutani, K; Mima, A; Kido, D; Kominato, H; Saito, N; Hakariya, M; Takemura, S; Nakagawa, K; Sugimoto, M; Sugiyama, A; Iwata, T. Porphyromonas gingivalis-derived lipopolysaccharide promotes mesangial cell fibrosis via transforming growth factor-beta1/Smad signaling pathway in high glucose JOURNAL OF DENTAL SCIENCES. 2025.04; 20 (2): 989-994. ( PubMed, DOI )

  3. Nakagawa, K; Watanabe, K; Mizutani, K; Takeda, K; Takemura, S; Sakaniwa, E; Mikami, R; Kido, D; Saito, N; Kominato, H; Hattori, A; Iwata, T. Genetic analysis of impaired healing responses after periodontal therapy in type 2 diabetes: Clinical and in vivo studies JOURNAL OF PERIODONTAL RESEARCH. 2024.08; 59 (4): 712-727. ( PubMed, DOI )

  4. Mizutani K, Minami I, Mikami R, Kido D, Takeda K, Nakagawa K, Takemura S, Saito N, Kominato H, Sakaniwa E, Konuma K, Izumi Y, Ogawa Y, Iwata T. Improvement of periodontal parameters following intensive diabetes care and supragingival dental prophylaxis in patients with type 2 diabetes: A prospective cohort study. Journal of clinical periodontology. 2024.03; 51 (6): 733-741. ( PubMed, DOI )

  5. Shu Takemura, Koji Mizutani, Risako Mikami, Keita Nakagawa, Masahiro Hakariya, Eri Sakaniwa, Natsumi Saito, Hiromi Kominato, Daisuke Kido, Kohei Takeda, Akira Aoki, Takanori Iwata. Enhanced periodontal tissue healing via vascular endothelial growth factor expression following low-level erbium-doped: yttrium, aluminum, and garnet laser irradiation: In vitro and in vivo studies. J Periodontol. 2023.11; 95 (9): 853-866. ( PubMed, DOI )

  6. Prima Buranasin, Hiromi Kominato, Koji Mizutani, Risako Mikami, Natsumi Saito, Kohei Takeda, Takanori Iwata. Influence of Reactive Oxygen Species on Wound Healing and Tissue Regeneration in Periodontal and Peri-Implant Tissues in Diabetic Patients. Antioxidants (Basel). 2023.09; 12 (9): ( PubMed, DOI )

  7. Takeda K, Mizutani K, Mikami R, Fujino A, Ito Y, Takeuchi S, Saito N, Iwata T. Morphological analysis of the impact of diabetes on gingival capillaries with non-invasive blood flow scope - A preliminary study. Journal of dental sciences. 2023.07; 18 (3): 1134-1140. ( PubMed, DOI )

  8. Mikami R, Mizutani K, Gohda T, Matsuyama Y, Gotoh H, Nakagawa K, Takemura S, Aoyama N, Matsuura T, Kido D, Takeda K, Saito N, Izumi Y, Iwata T. Malnutrition- inflammation- atherosclerosis (MIA) syndrome associates with periodontitis in end-stage renal disease patients undergoing hemodialysis: a cross-sectional study. Scientific reports. 2023.07; 13 (1): 11805. ( PubMed, DOI )

  9. Mikami R, Mizutani K, Matsuyama Y, Gohda T, Gotoh H, Aoyama N, Matsuura T, Kido D, Takeda K, Saito N, Fujiwara T, Izumi Y, Iwata T. Association of type 2 diabetes with periodontitis and tooth loss in patients undergoing hemodialysis. PLoS One. 2022.05; 17 (5): e0267494. ( PubMed, DOI )

  10. Hiromi Kominato, Kohei Takeda, Koji Mizutani, Risako Mikami, Daisuke Kido, Prima Buranasin, Natsumi Saito, Shu Takemura, Keita Nakagawa, Toshiyuki Nagasawa, Takanori Iwata. Metformin accelerates wound healing by Akt phosphorylation of gingival fibroblasts in insulin-resistant prediabetes mice. J Periodontol. 2022.02; 93 (2): 256-268. ( PubMed, DOI )

  11. Kohei Takeda, Koji Mizutani, Takanori Matsuura, Daisuke Kido, Risako Mikami, Prima Buranasin, Natsumi Saito, Hiromi Kominato, Shu Takemura, Keita Nakagawa, Takanori Iwata. Antioxidant effect of enamel matrix derivative for early phase of periodontal tissue regeneration in diabetes. J Periodontol. 2021.11; 93 (8): 1206-1217. ( PubMed, DOI )

  12. Koji Mizutani, Prima Buranasin, Risako Mikami, Kohei Takeda, Daisuke Kido, Kazuki Watanabe, Shu Takemura, Keita Nakagawa, Hiromi Kominato, Natsumi Saito, Atsuhiko Hattori, Takanori Iwata. Effects of Antioxidant in Adjunct with Periodontal Therapy in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis. Antioxidants (Basel). 2021.08; 10 (8): ( PubMed, DOI )

  13. Kohei Takeda, Koji Mizutani, Isao Minami, Daisuke Kido, Risako Mikami, Kuniha Konuma, Natsumi Saito, Hiromi Kominato, Shu Takemura, Keita Nakagawa, Yuichi Izumi, Yoshihiro Ogawa, Takanori Iwata. Association of periodontal pocket area with type 2 diabetes and obesity: a cross-sectional study. BMJ Open Diabetes Res Care. 2021.04; 9 (1): ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Takemura Shu, Mizutani Koji, Mikami Risako, Nakagawa Keita, Hakariya Masahiro, Sakaniwa Eri, Saito Natsumi, Kominato Hiromi, Kido Daisuke, Takeda Kohei, Aoki Akira, Iwata Takanori. 低出力Er:YAGレーザー照射による歯周組織治癒促進効果(Enhanced periodontal tissue healing following low-level Er:YAG laser irradiation). 日本歯周病学会会誌 2024.12.01

  2. Sakaniwa Eri, Mikami Risako, Mizutani Koji, Takeda Kohei, Kominato Hiromi, Saito Natsumi, Hakariya Masahiro, Nakagawa Keita, Takemura Shu, Sugimoto Mari, Sugiyama Ayu, Kido Daisuke, Mima Akira, Iwata Takanori. 糖尿病状態において歯周炎は腎線維症を介して腎機能を悪化させる(Periodontitis exacerbates renal function via renal fibrosis in diabetic conditions). 日本歯周病学会会誌 2024.12.01

  3. Nakagawa Keita, Watanabe Kazuki, Mizutani Koji, Takeda Kohei, Takemura Shu, Sakaniwa Eri, Mikami Risako, Kido Daisuke, Saito Natsumi, Kominato Hiromi, Hattori Atsuhiko, Iwata Takanori. 糖尿病患者における歯周病治療後の治癒反応障害に関する遺伝学的解析(Genetic Analysis of impaired Healing Responses after Periodontal Therapy in Diabetes). 日本歯周病学会会誌 2024.12.01

  4. Saito Natsumi, Mikami Risako, Mizutani Koji, Aoyama Norio, Matsuura Takanori, Suda Tomonari, Takeda Kohei, Aida Jun, Izumi Yuichi, Iwata Takanori. 社会経済的状況が肥満および歯周炎に与える影響(The impact of socio-economic status on obesity and periodontitis). 日本歯周病学会会誌 2024.12.01

  5. Moreira BA, Mizutani K, Saito N, Takemura S, Chen L, Ohsugi Y, Iwata T, Aoki A.. Effects of Low-Level Er: YAG Laser Irradiation on Human Umbilical Vein Endothelial Cells in Hyperglycemia. The 18th Congress of World Federation for Laser Dentistry (WFLD) 2024.11.11 The Rebouças Convention Center, Sao Paulo, Brazil

  6. Shu Takemura, Koji Mizutani, Risako Mikami, Keita Nakagawa, Masahiro Hakariya, Eri Sakaniwa, Natsumi Saito, Hiromi Kominato, Daisuke Kido, Kohei Takeda, Akira Aoki, Takanori Iwata. Enhanced periodontal tissue healing following low-level Er:YAG laser irradiation. The American Academy of Periodontology's 110th Annual Meeting 2024.11 San Diego, USA

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