Graduating School 【 display / non-display 】
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Tokyo Medical and Dental University, Faculty of Medicine, 2016.03, Graduated
Campus Career 【 display / non-display 】
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2017.04-2018.03Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Central Clinical Facilities, Professional Development Center, Trainee Resident
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2018.04Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Central Clinical Facilities, Professional Development Center, Trainee Resident
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2021.04-NowTokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Division of Bio-Environmental Response, Department of Rheumatology, Graduate Student
Published Papers & Misc 【 display / non-display 】
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Komiya, Y; Kamiya, M; Oba, S; Kawata, D; Iwai, H; Shintaku, H; Suzuki, Y; Miyamoto, S; Tobiume, M; Kanno, T; Ainai, A; Suzuki, T; Hasegawa, H; Hosoya, T; Yasuda, S. Necroptosis in alveolar epithelial cells drives lung inflammation and injury caused by SARS-CoV-2 infection BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 2024.12; 1870 (8): 167472. ( PubMed, DOI )
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Kawata D, Iwai H, Oba S, Komiya Y, Koike R, Miyamoto S, Kanno T, Ainai A, Suzuki T, Hosoya T, Yasuda S. Diverse pro-inflammatory ability of mutated spike protein derived from variant strains of SARS-CoV-2. Cytokine. 2024.06; 178 156592. ( PubMed, DOI )
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Hosoya T, Oba S, Komiya Y, Kawata D, Kamiya M, Iwai H, Miyamoto S, Kataoka M, Tobiume M, Kanno T, Ainai A, Sato H, Hirakawa A, Mitsui Y, Satoh T, Wakabayashi K, Yamada T, Otomo Y, Miyazaki Y, Hasegawa H, Suzuki T, Yasuda S. Apple-shaped obesity: A risky soil for cytokine-accelerated severity in COVID-19. Proceedings of the National Academy of Sciences of the United States of America. 2023.05; 120 (22): e2300155120. ( PubMed, DOI )
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Itakura T, Sasaki H, Hosoya T, Yamaguchi T, Mimori E, Saimon Y, Iwai H, Umezawa N, Kawata D, Kimura N, Kurata M, Shimizu M, Yasuda S. A novel gain-of-function missense variant in PLCG2 associated with autoinflammation and hypergammaglobulinemia. Rheumatology (Oxford, England). 2023.04; 62 (11): e319-e321. ( PubMed, DOI )
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Fujiwara S, Kawamoto A, Motobayashi M, Hibiya S, Takenaka K, Shimizu H, Saito E, Fujii T, Nagahori M, Kawata D, Umezawa N, Hosoya T, Yasuda S, Ohtsuka K, Okamoto R. Hemorrhagic gastric ulcer in a patient with Behcet's disease successfully treated with infliximab. DEN open. 2023.04; 3 (1): e196. ( PubMed, DOI )
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Fujiwara Shun, Kawamoto Ami, Motobayashi Maiko, Hibiya Shuji, Takenaka Kento, Shimizu Hiromichi, Saito Eiko, Fujii Toshimitsu, Nagahori Masakazu, Kawata Daisuke, Umezawa Natsuka, Hosoya Tadashi, Yasuda Shinsuke, Ohtsuka Kazuo, Okamoto Ryuichi. インフリキシマブが奏効したベーチェット病患者に認められた出血性胃潰瘍(Hemorrhagic gastric ulcer in a patient with Behcet's disease successfully treated with infliximab) DEN Open. 2023.04; 3 (1): 1 of 5-5 of 5. ( ichushi )
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Umezawa N, Sasaki H, Furusawa H, Kawata D, Hata C, Yasuda S. Development of vasculitis in a case with severe asthma treated with benralizumab and low-dose corticosteroid. Allergology international : official journal of the Japanese Society of Allergology. 2023.01; 72 (1): 179-181. ( PubMed, DOI )
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Oba S, Hosoya T, Kaneshige R, Kawata D, Yamaguchi T, Mitsumura T, Shimada S, Shibata S, Tateishi T, Koike R, Tohda S, Hirakawa A, Yoko N, Otomo Y, Nojima J, Miyazaki Y, Yasuda S. Thrombosis and antiphospholipid antibodies in Japanese COVID-19: based on propensity score matching. Frontiers in immunology. 2023; 14 1227547. ( PubMed, DOI )
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Oba, S; Hosoya, T; Kawata, D; Lee, W; Kamiya, M; Komiya, Y; Iwai, H; Nukui, Y; Tohda, S; Yasuda, S. SARS-COV-2 INFECTION CAUSED THROMBOSIS IN THE LUPUS MODEL WITH ANTIPHOSPHOLIPID ANTIBODY, WHEREAS COVID-19 ASSOCIATED THROMBOSIS WAS IRRELEVANT IN PATIENTS WITH POSITIVE ANTIPHOSPHOLIPID ANTIBODY ANNALS OF THE RHEUMATIC DISEASES. 2022.06; 81 331-332. ( DOI )
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Oba Seiya, Hosoya Tadashi, Amamiya Miki, Mitsumura Takahiro, Kawata Daisuke, Sasaki Hirokazu, Kamiya Mari, Yamamoto Akio, Ando Takahiro, Shimada Sho, Shirai Tsuyoshi, Okamoto Tsukasa, Tateishi Tomoya, Endo Akira, Aiboshi Junichi, Nosaka Nobuyuki, Yamanouchi Hideo, Ugawa Toyomu, Nagaoka Eiki, Oi Keiji, Tao Susumu, Maejima Yasuhiro, Tanaka Yukie, Tanimoto Kousuke, Takeuchi Hiroaki, Tohda Shuji, Hirakawa Akihiro, Sasano Tetsuo, Arai Hirokuni, Otomo Yasuhiro, Miyazaki Yasunari, Yasuda Shinsuke. Arterial and Venous Thrombosis Complicated in COVID-19: A Retrospective Single Center Analysis in Japan. Front Cardiovasc Med. 2021; 8 767074. ( PubMed, DOI )
Conference Activities & Talks 【 display / non-display 】
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Komiya Yoji, Kamiya Mari, Hosoya Tadashi, Oba Seiya, Kawata Daisuke, Iwai Hideyuki, Miyamoto Sho, Kanno Takayuki, Ainai Akira, Suzuki Tadaki, Hasegawa Hideki, Yasuda Shinsuke. 肺胞上皮細胞におけるFASを介したネクロプトーシスの抑制はCOVID-19マウスモデルにおける肺傷害とその後のインフラマソーム活性化を抑制する(Inhibition of FAS-mediated necroptosis in alveolar epithelial cell suppresses lung injury and subsequent inflammasome activation in murine COVID-19 model). 日本免疫学会総会・学術集会記録 2023.12.01
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Hosoya Tadashi, Oba Seiya, Komiya Yoji, Kawata Daisuke, Kamiya Mari, Iwai Hideyuki, Miyamoto Sho, Kanno Takayuki, Ainai Akira, Suzuki Tadaki, Hasegawa Hideki, Yasuda Shinsuke. 感染と免疫II COVID-19の肥満患者における悪化の根本的なメカニズム(Infection and Immunity II The underlying mechanism of the deterioration in obese patients with COVID-19). 日本免疫学会総会・学術集会記録 2022.11.01
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S. Oba, T. Hosoya, D. Kawata, W. Lee, M. Kamiya, Y. Komiya, H. Iwai, Y. Nukui, S. Tohda, S. Yasuda. POS0197 SARS-CoV-2 INFECTION CAUSED THROMBOSIS IN THE LUPUS MODEL WITH ANTIPHOSPHOLIPID ANTIBODY, WHEREAS COVID-19 ASSOCIATED THROMBOSIS WAS IRRELEVANT IN PATIENTS WITH POSITIVE ANTIPHOSPHOLIPID ANTIBODY. EULAR 2022 2022.06.01 Copenhagen, Denmark