Personnel Information

写真a

IMAI Minoru


Job title

URA

Birth date

1968

Laboratory Phone number

+81-3-5803-4874

Laboratory Fax number

+81-3-5803-0396

Mail Address

m.imai.adm@tmd.ac.jp

Homepage URL

https://www.tmd.ac.jp/ru/innv/english/index.html

Graduating School 【 display / non-display

  • Nagoya University, Faculty of Science, Department of Chemistry, 1991.03, Graduated

Graduate School 【 display / non-display

  • Nagoya University, Graduate School, Division of Natural Science, Department of Chemistry, Master's Course, 1993.03, Completed

  • Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology Track, Doctor's Course, 2015.03, Completed

Degree 【 display / non-display

  • Doctor of Philosophy in Science, Tokyo Medical and Dental University

  • Master of Science, Nagoya University

Campus Career 【 display / non-display

  • 2012.04
    -
    2015.03
    Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Biomolecular Chemistry, Organic and Medicinal Chemistry, Graduate Student
  • 2017.05
    -
    2019.05
    Tokyo Medical and Dental University, Research University Promotion Organization, Research Administration Division, URA
  • 2018.04
    -
    Now
    Tokyo Medical and Dental University, Research University Promotion Organization, Research Administration Division, Project Junior Associate Professor
  • 2017.05
    -
    2020.03
    Tokyo Medical and Dental University, Institute of Research, Division for Research Innovation, -, URA
  • 2020.04
    -
    Now
    Tokyo Medical and Dental University, , , URA
  • 2019.06
    -
    Now
    Tokyo Medical and Dental University, Research University Promotion Organization, Research Administration Division, URA

▼display all

External Career 【 display / non-display

  • 1993.04
    -
    2003.09
    Teijin Limited, Research Scientist
  • 1997.07
    -
    1998.03
    CombiChem, Inc., Visiting Reseacher
  • 2003.10
    -
    2006.03
    Teijin Pharma Limited, Pharmaceutical Discovery Planning Department, Manager
  • 2006.04
    -
    2008.03
    Teijin Pharma Limited, Pharmaceutical Discovery Research Laboratories I, Group Leader
  • 2008.04
    -
    2017.04
    Teijin Pharma Limited, Pharmaceutical Development Coordination Department, Project Manager

Academic Society Affiliations 【 display / non-display

  • The Japanese Society of Clinical Pharmacology and Therapeutics

  • Japan Society of Clinical Trials and Research

  • Project Management Association of Japan (PMAJ)

  • The Pharmaceutical Society of Japan

  • The Pharmaceutical Society of Japan, Division of Medicinal Chemistry

Qualification Acquired 【 display / non-display

  • Project Management Specialist

 

Published Papers & Misc 【 display / non-display

  1. Minoru Imai, Tatsuki Shiota, Ken-ichiro Kataoka, Christine M Tarby, Wilna J Moree, Takaharu Tsutsumi, Masaki Sudo, Michele M Ramirez-Weinhouse, Daniel Comer, Chung-Ming Sun, Shinsuke Yamagami, Hiroko Tanaka, Takuya Morita, Takahiko Hada, Jonathan Greene, Doug Barnum, John Saunders, Peter L Myers, Yoshinori Kato, Noriaki Endo. Small molecule inhibitors of the CCR2b receptor. Part 1: Discovery and optimization of homopiperazine derivatives. Bioorganic & Medicinal Chemistry Letters. 2004.11; 14 (21): 5407-5411. ( PubMed, DOI )

  2. Wilna J Moree, Ken-ichiro Kataoka, Michele M Ramirez-Weinhouse, Tatsuki Shiota, Minoru Imai, Masaki Sudo, Takaharu Tsutsumi, Noriaki Endo, Yumiko Muroga, Takahiko Hada, Hiroko Tanaka, Takuya Morita, Jonathan Greene, Doug Barnum, John Saunders, Yoshinori Kato, Peter L Myers, Christine M Tarby. Small molecule antagonists of the CCR2b receptor. Part 2: Discovery process and initial structure-activity relationships of diamine derivatives. Bioorganic & Medicinal Chemistry Letters. 2004.11; 14 (21): 5413-5416. ( PubMed, DOI )

  3. Wilna J Moree, Ken-ichiro Kataoka, Michele M Ramirez-Weinhouse, Tatsuki Shiota, Minoru Imai, Takaharu Tsutsumi, Masaki Sudo, Noriaki Endo, Yumiko Muroga, Takahiko Hada, Dewey Fanning, John Saunders, Yoshinori Kato, Peter L Myers, Christine M Tarby. Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series. Bioorganic & Medicinal Chemistry Letters. 2008.03; 18 (6): 1869-1873. ( PubMed, DOI )

  4. Tomomi Kosugi, Dale R Mitchell, Aiko Fujino, Minoru Imai, Mika Kambe, Shinji Kobayashi, Hiroaki Makino, Yohei Matsueda, Yasuhiro Oue, Kanji Komatsu, Keiichiro Imaizumi, Yuri Sakai, Satoshi Sugiura, Osami Takenouchi, Gen Unoki, Yuko Yamakoshi, Vicky Cunliffe, Julie Frearson, Richard Gordon, C John Harris, Heidi Kalloo-Hosein, Joelle Le, Gita Patel, Donald J Simpson, Brad Sherborne, Peter S Thomas, Naotaka Suzuki, Midori Takimoto-Kamimura, Ken-ichiro Kataoka. Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2) as an antiinflammatory target: discovery and in vivo activity of selective pyrazolo[1,5-a]pyrimidine inhibitors using a focused library and structure-based optimization approach. Journal of Medicinal Chemistry. 2012.08; 55 (15): 6700-6715. ( PubMed, DOI )

  5. Takagi Masatoshi, Ogawa Chitose, Aoki-Nogami Yuki, Iehara Tomoko, Ishibashi Eri, Imai Minoru, Kihara Tetsuro, Nobori Kiyoshi, Hasebe Kazuhisa, Mizutani Shuki, Kimura Toshimi, Nagata Masashi, Yasuhara Masato, Yoshimura Kenichi, Yorozu Pariko, Hosoi Hajime, Koike Ryuji. Phase I clinical study of oral olaparib in pediatric patients with refractory solid tumors: study protocol BMC PEDIATRICS. 2019.01; 19 (1): 31. ( PubMed, DOI )

Conference Activities & Talks 【 display / non-display

  1. Masatoshi Takagi, Chitose Ogawa, Tomoko Iehara, Yuki Aoki-Nogami, Eri Isibashi, Minoru Imai, Toshimi Kimura, Masashi Nagata, Masato Yasuhara, Mitsuko Masutani, Kenichi Yoshimura, Daisuke Tomizawa, Atsushi Ogawa, Kan Yonemori, Tetsuro Kihara, Kiyoshi Nobori, Kazuhisa Hasebe, Shuki Mizutani, Tomohiro Morio, Hajime Hosoi, Ryuji Koike. First In Children Phase I Clinical Study Of Oral Olaparib In Pediatric Patients With Refractory Solid Tumors. SIOP2021 2021.10.24 Honolulu(Web)