基本情報

写真a

及川 悠(オイカワ ユウ)

OIKAWA Yu


職名

助教

研究分野・キーワード

口腔がん

取得学位 【 表示 / 非表示

  • 博士(歯学)  東京医科歯科大学

経歴(学内) 【 表示 / 非表示

  • 2013年04月
    -
    2017年03月
    東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 口腔機能再構築学講座 顎口腔外科学 大学院生
  • 2017年10月
    -
    2018年03月
    東京医科歯科大学 (旧組織)歯学部附属病院 診療科 回復系診療科 口腔外科外来 医員
  • 2020年04月
    -
    2021年09月
    東京医科歯科大学 (旧組織)歯学部附属病院 診療科 回復系診療科 口腔外科外来 特任助教
  • 2021年10月
    -
    2022年03月
    東京医科歯科大学 病院 歯系診療部門 口腔外科系診療領域 口腔外科 特任助教
  • 2022年04月
    -
    2024年09月
    東京医科歯科大学 病院 歯系診療部門 口腔外科系診療領域 口腔外科 助教
  • 2024年10月
    -
    2025年11月
    東京科学大学 教育研究組織 病院 歯系診療部門・口腔外科系診療領域 口腔外科 助教
  • 2025年12月
    -
    現在
    東京科学大学 教育研究組織 大学院 医歯学専攻・口腔機能再構築学講座 顎口腔腫瘍外科学分野 助教

▼全件表示

 

競争的資金等の研究課題 【 表示 / 非表示

  • 口腔内多発がんにおける口腔内細菌叢のメタゲノム解析

    文部科学省/日本学術振興会

論文・総説 【 表示 / 非表示

  1. Ohyama Y, Michi Y, Inaba Y, Hasegawa K. Use of cold devices for tumor resection improves the engraftment rate of full-thickness skin grafts in buccal mucosal cancer Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2025.11; 37 (6): 1181-1185.

  2. Okuyama K, Yanamoto S. Acid-Resistant Oral Microbiome on Oral Cancer Development JAMA Otolaryngology-Head & Neck Surgery. 2025.11; 151 (11): 1102-1103. ( PubMed, DOI )

  3. Okuyama K, Debnath K C, Islam S, Yanamoto S. From Wound Coverage to Functional Healing: A Narrative Review of Biomaterial Applications in Head and Neck Mucosal Defects Head & Neck. 2025.11; 47 (11): 3201-3208. ( PubMed, DOI )

  4. Nishii N, Tsushima F, Sakurai J, Su Y, Kinoshita N, Oikawa Y, Hirotsu Y, Ohsako T, Furusawa-Nishii E, Omata M, Harada H. TCR repertoire analysis reveals predominant local clonal expansion of T cells with minimal circulation in oral lichenoid contact lesions Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2025.08; ( DOI )

  5. Kuroshima T, Kinoshita N, Nishii N, Oikawa Y, Kugimoto T, Hirai H, Tomioka H, Michi Y, Harada H. Survival Impact and Risk Factors of Cervical Lymph Node Metastasis in Maxillary Gingival Squamous Cell Carcinoma: A Retrospective Study of 81 Patients. Head Neck. 2025.08; ( PubMed, DOI )

  6. Okuyama K, Fujimoto J, Yanamoto S. HPV-positive HNSCC and Fc-silent PD-1 blockade: a clinical discrepancy that raises next immunological questions Journal for ImmunoTherapy of Cancer. 2025.08; 13 (8): e012728. ( PubMed, DOI )

  7. Kakuta R, Takemoto A, Tanimoto K, Noji R, Kudo R, Kano Y, Ando Y, Simoi T, Kinugasa Y, Ikeda S. Characterization of a novel comprehensive genomic profiling test with better detection of heterozygous deletions and RNA-based gene fusion analysis. The oncologist. 2025.08; 30 (8): ( PubMed, DOI )

  8. Oikawa Y, Noji R, Shimono H, Shimizu R, Kinoshita N, Nishii N, Kugimoto T, Kuroshima T, Harada H. A study on direct metastasis to levels III, IV in oral tongue squamous cell carcinoma Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2025.05; 37 (3): 446-449. ( DOI )

  9. Okuyama k, Yanamoto S. Comment on "The characterization of tumor immune microenvironment after neoadjuvant immunotherapy in head and neck squamous cell cancer using multiplex immunohistochemistry" Oral Oncology. 2025.03; 162 107213. ( PubMed, DOI )

  10. Ohyama Y, Hasegawa K, Uzawa N, Sawada T, Sano M, Yamashiro M, Michi Y, Inaba Y, Myo K, Iwasaki T, Terauchi M, Yoda T. Reduction of ischemic time using the pull-through technique for scapular free flap Oral and Maxillofacial Surgery. 2025.01; 29 (1): 25.

  11. Tomoka Matsumura, Jun Aida, Yushi Abe, Yu Oikawa, Takeshi Kuroshima, Hiroyuki Harada, Shigeru Maeda. Obesity and postoperative flap complications in maxillofacial reconstruction surgery ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY. 2024.12; in press

  12. Rika Noji, Kohki Tohyama, Shin Nakamura, Takahiro Naito, Yu Oikawa, Takeshi Kuroshima, Hirofumi Tomioka, Yasuyuki Michi, Sadakatsu Ikeda, Takahiro Asakage, Masahiko Miura, Yasuo Hamamoto, Hiroyuki Harada, Yoshihito Kano. Dynamic Changes in Circulating Tumor DNA During Immunotherapy for Head and Neck Cancer: SHIZUKU-HN Study. Int J Mol Sci. 2024.12; 26 (1): 235. ( PubMed, DOI )

  13. Yamaguchi K, Okumura T, Oikawa Y, Nakagawa K, Yoshimi K, Harada H, Tohara H. Effect of oral intake initiation-establishment interval on hospital stay after oral cancer surgery Oral Diseases. 2024.05;

  14. Hirofumi Tomioka, Naoto Nishii, Yu Oikawa, Takuma Kugimoto, Takeshi Kuroshima, Hideaki Hirai, Kou Kayamori, Atsushi Kaida, Masahiko Miura, Hiroyuki Harada. Clinicopathological analysis of 134 patients with squamous cell carcinoma of the mandibular gingiva. Heliyon. 2023.11; 10 (1): e23120. ( PubMed, DOI )

  15. Takuma Kugimoto, Naoto Nishii, Yu Oikawa, Takeshi Kuroshima, Hideaki Hirai, Hirofumi Tomioka, Yasuyuki Michi, Kou Kayamori, Junichiro Sakamoto, Joe Iwanaga, R Shane Tubbs, Tohru Ikeda, Masahiko Miura, Hiroyuki Harada. Invasion of the bucco-mandibular space by oral squamous cell carcinoma: histopathological analysis of invasion pattern. Front Oncol. 2023.10; 13 1168376. ( PubMed, DOI )

  16. Naoya Kinoshita, Hirofumi Tomioka, Yu Oikawa, Yuki Fukawa, Tohru Ikeda, Hiroyuki Harada. A case of sclerosing odontogenic carcinoma of the mandible with a review of the literature. J Oral Sci. 2023.08; 65 (4): 281-283. ( PubMed, DOI )

  17. Hideaki Hirai, Naoto Nishii, Yu Oikawa, Toshimitsu Ohsako, Takuma Kugimoto, Takeshi Kuroshima, Hirofumi Tomioka, Yasuyuki Michi, Kou Kayamori, Tohru Ikeda, Hiroyuki Harada. Buccinator muscle invasion is a risk factor for cervical lymph node metastasis in squamous cell carcinoma of the buccal mucosa: A retrospective study. Oncol Lett. 2023.06; 25 (6): 226. ( PubMed, DOI )

  18. Michi Yasuyuki, Harada Hiroyuki, Oikawa Yu, Okuyama Kohei, Kugimoto Takuma, Kuroshima Takeshi, Hirai Hideaki, Mochizuki Yumi, Shimamoto Hiroaki, Tomioka Hirofumi, Kachi Hirokazu, Sakamoto Jun-ichiro, Kayamori Kou, Yoda Tetsuya. Clinical manifestations of diffuse large B-cell lymphoma that exhibits initial symptoms in the maxilla and mandible: a single-center retrospective study BMC ORAL HEALTH. 2022.01; 22 (1): 20. ( PubMed, DOI )

  19. Harada Hiroyuki, Tomioka Hirofumi, Hirai Hideaki, Kuroshima Takeshi, Oikawa Yu, Nojima Hitomi, Sakamoto Junichiro, Kurabayashi Tohru, Kayamori Kou, Ikeda Tohru. MRI before biopsy correlates with depth of invasion corrected for shrinkage rate of the histopathological specimen in tongue carcinoma SCIENTIFIC REPORTS. 2021.10; 11 (1): 20992. ( PubMed, DOI )

  20. Kuroshima T, Onozato Y, Oikawa Y, Ohsako T, Kugimoto T, Hirai H, Tomioka H, Michi Y, Miura M, Yoshimura R, Harada H. Prognostic impact of lingual lymph node metastasis in patients with squamous cell carcinoma of the tongue: a retrospective study. Scientific reports. 2021.10; 11 (1): 20535. ( PubMed, DOI )

  21. Hiroyuki Harada, Hiroaki Shimamoto, Yu Oikawa, Takeshi Kuroshima, Hirofumi Tomioka, Hideaki Hirai, Fumihiko Tsushima, Yasuyuki Michi. Mandibular Reconstruction with Scapular Systems: A Single-Center Case Series Involving 208 Flaps. Plast Reconstr Surg. 2021.09; 148 (3): 625-634. ( PubMed, DOI )

  22. Kaida Atsushi, Yamamoto Satomi, Parrales Alejandro, Young Eric D., Ranjan Atul, Alalem Mohamed A., Morita Kei-ichi, Oikawa Yu, Harada Hiroyuki, Ikeda Tohru, Thomas Sufi M., Diaz Francisco J., Iwakuma Tomoo. DNAJA1 promotes cancer metastasis through interaction with mutant p53 ONCOGENE. 2021.08; 40 (31): 5013-5025. ( PubMed, DOI )

  23. Oikawa Yu, Tanaka Kae, Ohsako Toshimitsu, Kugimoto Takuma, Kuroshima Takeshi, Hirai Hideaki, Tomioka Hirofumi, Shimamoto Hiroaki, Michi Yasuyuki, Sakamoto Kei, Ikeda Tohru, Harada Hiroyuki. Comparison of Clinicopathological Characteristics Between the Anterior and Posterior Type of Squamous Cell Carcinoma of the Floor of the Mouth: The Anterior Type Is a Risk Factor for Multiple Primary Cancer FRONTIERS IN ONCOLOGY. 2021.06; 11 682428. ( PubMed, DOI )

  24. Oikawa Y, Kugimoto T, Kashima Y, Okuyama K, Ohsako T, Kuroshima T, Hirai H, Tomioka H, Shimamoto H, Michi Y, Harada H. Surgical treatment for oral tongue squamous cell carcinoma: A retrospective study of 432 patients. Global health & medicine. 2021.06; 3 (3): 157-162. ( PubMed, DOI )

  25. Tran Cuong, Kuroshima Takeshi, Oikawa Yu, Michi Yasuyuki, Kayamori Kou, Harada Hiroyuki. Clinicopathological and immunohistochemical characteristics of pigmented oral squamous cell carcinoma ONCOLOGY LETTERS. 2021.04; 21 (4): 339. ( PubMed, DOI )

  26. Yamada Ichiro, Yohino Norio, Yokokawa Misaki, Oikawa Yu, Harada Hiroyuki, Hikishima Keigo, Kurabayashi Tohru, Saida Yukihisa, Tateishi Ukihide, Ohata Yae. Diffusion tensor imaging of oral carcinoma: Clinical evaluation and comparison with histopathological findings MAGNETIC RESONANCE IMAGING. 2021.04; 77 99-108. ( PubMed, DOI )

  27. Shimono H, Hirai H, Oikawa Y, Mochizuki Y, Kuroshima T, Tomioka H, Kayamori K, Ikeda T, Harada H. Metastatic tumors in the oral region: a retrospective chart review of clinical characteristics and prognosis. Oral surgery, oral medicine, oral pathology and oral radiology. 2021.04; 132 (6): 648-652. ( PubMed, DOI )

  28. Mochizuki Y, Marukawa E, Harada H, Kinoshita N, Nakatani R, Oikawa Y, Hirai H, Tomioka H, Yoda T, Nakamura S, Kurabayashi T. Postoperative morphological changes over time of vascularized scapular bone used for mandibular reconstruction: A retrospective cohort study. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. 2021.03; 74 (9): 1984-1990. ( PubMed, DOI )

  29. Tomioka H, Yamagata Y, Oikawa Y, Ohsako T, Kugimoto T, Kuroshima T, Hirai H, Shimamoto H, Harada H. Risk factors for distant metastasis in locoregionally controlled oral squamous cell carcinoma: a retrospective study Sci Rep. 2021.03; 11 (1): 5213. ( PubMed, DOI )

  30. Yokokawa Misaki, Morita Kei-ichi, Oikawa Yu, Kayamori Kou, Sakamoto Kei, Ikeda Tohru, Harada Hiroyuki. Co-expression of EGFR and MET has a synergistic effect on the prognosis of patients with oral squamous cell carcinoma JOURNAL OF ORAL PATHOLOGY & MEDICINE. 2020.03; 49 (3): 235-242. ( PubMed, DOI )

  31. Oikawa Yu, Michi Yasuyuki, Tsushima Fumihiko, Tomioka Hirofumi, Mochizuki Yumi, Kugimoto Takuma, Osako Toshimitsu, Nojima Hitomi, Yokokawa Misaki, Kashima Yoshihisa, Harada Hiroyuki. Management of retropharyngeal lymph node metastasis in oral cancer ORAL ONCOLOGY. 2019.12; 99 104471. ( PubMed, DOI )

  32. Shimizu R, Tanaka K, Oikawa Y, Tomioka H, Kayamori K, Ikeda T, Yoshioka T, Ebihara A, Harada H. Epithelioid cell granuloma with caseating necrosis possibly caused by periapical periodontitis: a case report. Journal of medical case reports. 2018.12; 12 (1): 365. ( PubMed, DOI )

  33. Yamada Ichiro, Yoshino Norio, Hikishima Keigo, Sakamoto Junichiro, Yokokawa Misaki, Oikawa Yu, Harada Hiroyuki, Kurabayashi Tohru, Saida Yukihisa, Tateishi Ukihide, Yukimori Akane, Izumo Toshiyuki, Asahina Shun. Oral carcinoma: Clinical evaluation using diffusion kurtosis imaging and its correlation with histopathologic findings MAGNETIC RESONANCE IMAGING. 2018.09; 51 69-78. ( PubMed, DOI )

  34. Hirai Hideaki, Tomioka Hirofumi, Mochizuki Yumi, Oikawa Yu, Tsushima Fumihiko, Harada Hiroyuki. Clinical Course of Oral Squamous Cell Carcinoma in Patients on Immunosuppressant and Glucocorticoid Therapy JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY. 2017.09; 75 (9): 1980-1986. ( PubMed, DOI )

  35. Shimamoto Hiroaki, Oikawa Yu, Osako Toshimitsu, Hirai Hideaki, Mochizuki Yumi, Tanaka Kae, Tomioka Hirofumi, Harada Hiroyuki. Neck failure after elective neck dissection in patients with oral squamous cell carcinoma ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY. 2017.07; 124 (1): 32-36. ( PubMed, DOI )

  36. Yukimori Akane, Oikawa Yu, Morita Kei-ichi, Chi Thi Kim Nguyen, Harada Hiroyuki, Yamaguchi Satoshi, Kayamori Kou, Yamaguchi Akira, Ikeda Tohru, Sakamoto Kei. Genetic basis of calcifying cystic odontogenic tumors PLOS ONE. 2017.06; 12 (6): e0180224. ( PubMed, DOI )

  37. Oikawa Yu, Morita Kei-ichi, Kayamori Kou, Tanimoto Kousuke, Sakamoto Kei, Katoh Hiroto, Ishikawa Shumpei, Inazawa Johji, Harada Hiroyuki. Receptor tyrosine kinase amplification is predictive of distant metastasis in patients with oral squamous cell carcinoma CANCER SCIENCE. 2017.02; 108 (2): 256-266. ( PubMed, DOI )

  38. Mochizuki Y, Tomioka H, Tushima F, Shimamoto H, Hirai H, Oikawa Y, Harada H. Clinical evaluation of coverage of open wounds: Polyglycolic acid sheet with fibrin glue spray vs split thickness skin. Annals of maxillofacial surgery. 2016.07; 6 (2): 228-234. ( PubMed, DOI )

  39. Morita Kei-ichi, Naruto Takuya, Tanimoto Kousuke, Yasukawa Chisato, Oikawa Yu, Masuda Kiyoshi, Imoto Issei, Inazawa Johji, Omura Ken, Harada Hiroyuki. Simultaneous Detection of Both Single Nucleotide Variations and Copy Number Alterations by Next-Generation Sequencing in Gorlin Syndrome PLOS ONE. 2015.11; 10 (11): e0140480. ( PubMed, DOI )

  40. 角倉可奈子,及 川 悠,下 野 宏 晃,野 地 理 夏,布 川 裕 規,原 田 浩 之. 再発腫瘍切除の12年後に咀嚼筋隙に再々発をきたした上顎歯肉粘表皮癌の1例 日本口腔外科学会誌. 2025.08; 71 (8): 374-380. ( DOI )

  41. 柳下寿郎, 明石良彦, 莇生田整治, 石川文隆, 伊藤由美, 猪俣 徹, 河内 洋, 佐藤由紀子, 里見貴史, 関川翔一, 相馬智也, 舘原誠晃, 野村武史, 藤井誠志, 松坂賢一, 辺見卓男, 道 泰之, 八木原一博, 山城正司, 日本口腔腫瘍学会口腔表在癌ワーキンググループ. WHO頭頸部腫瘍分類の改訂(第5版)に伴う口腔潜在的悪性疾患と口腔上皮性異形成の臨床と病理 日本口腔腫瘍学会誌. 2025.06; 37 (2): 41-51.

  42. 高坂 光, 平井 秀明, 及川 悠, 大迫 利光, 釘本 琢磨, 黒嶋 雄志, 富岡 寛文, 島本 裕彰, 道 泰之, 原田 浩之. 遊離皮弁の鬱血に対するmedical leech(医療用ヒル)の有効性に関する臨床的検討 日本口腔外科学会雑誌. 2020.12; 66 (12): 596-600. ( 医中誌 )

  43. 福田 修平, 黒嶋 雄志, 富岡 寛文, 及川 悠, 原田 浩之. 長期経過を辿って潜在性頸部リンパ節転移が顕在化した舌扁平上皮癌の3例 日本口腔腫瘍学会誌. 2019.12; 31 (4): 197-202. ( 医中誌 )

  44. 上杉 篤史, 津島 文彦, 横川 美咲, 及川 悠, 望月 裕美, 原田 浩之. 難治性口腔潰瘍を契機として腸管ベーチェット病疑いに至った1例 日本口腔外科学会雑誌. 2019.03; 65 (3): 194-198. ( 医中誌 )

  45. 平井 秀明, 横川 美咲, 及川 悠, 大迫 利光, 望月 裕美, 田中 香衣, 富岡 寛文, 島本 裕彰, 原田 浩之. 高齢者口腔癌治療の実際と今後の方向性 後期高齢者口腔扁平上皮癌症例の臨床的検討 日本口腔腫瘍学会誌. 2017.12; 29 (4): 158-164. ( 医中誌 )

▼全件表示

書籍等出版物 【 表示 / 非表示

  1. 原田 浩之, 及川 悠. 重篤副作用疾患別対応マニュアル. 厚生労働省, 2025.03 薬剤関連顎骨壊死・顎骨骨髄炎

  2. 原田浩之 他. 必ず上達 歯科小手術 ここからはじめる!これならできる!テクニック. 2024.03

  3. 桐田忠昭、鄭 漢忠、池邉哲郎、原田浩之、古郷幹彦. 一般臨床家、口腔外科医のための口腔外科ハンドマニュアル '22. クインテッセンス出版株式会社, 2022.07 若手口腔外科医からのメッセージ

講演・口頭発表等 【 表示 / 非表示

  1. 及川 悠, 木下直哉, 清水六花, 西井直人, 大迫利光, 釘本琢磨, 黒嶋雄志, 平井秀明, 富岡寛文, 道 泰之, 原田浩之. 口腔扁平上皮癌における下顎管浸潤と遠隔転移との関連. 2023.01.27

  2. 44. 富岡寛文, 及川 悠, 奥山紘平, 大迫利光, 釘本琢磨, 黒嶋雄志, 平井秀明, 島本裕彰, 道 泰之, 原田浩之.. 口腔扁平上皮癌に対し免疫チェックポイント阻害薬を使用した16例の検討. 第65回口腔外科学会総会学術大会 2020.11.13 名古屋市

その他業績 【 表示 / 非表示

  • 「 口底癌と重複癌に関する新知見 」―前方型口底癌の予後不良因子はタバコ関連疾患と重複癌である―,2021年07月

    Frontiers in Oncology