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TAKAHASHI Kentaro
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Graduating School 【 display / non-display 】
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Tokyo Medical and Dental University, Faculty of Medicine, 2006.03, Graduated
Graduate School 【 display / non-display 】
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Tokyo Medical and Dental University, Graduate School, Division of Medical Sciences, Doctor's Course, 2016.03, Completed
Degree 【 display / non-display 】
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PhD (Medical), Tokyo Medical and Dental University
Campus Career 【 display / non-display 】
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2008.04-2009.03Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Cardiovascular Medicine, Resident
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2011.04-2016.03Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Systemic Organ Regulation, Cardiovascular Medicine, Graduate Student
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2016.04-2017.11Tokyo Medical and Dental University, Medical Research Institute, Advanced Molecular Medicine, Bio-informational Pharmacology, Project Assistant Professor
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2023.10-NowTokyo Medical and Dental University, Institute of Research, Research Facility Cluster, Bioresource Research Center, Assistant Professor
External Career 【 display / non-display 】
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2006.04-2008.03Yokosuka Kyosai Hospital, Trainee Resident
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2009.04-2011.03Tsuchiura Kyodo General Hospital, Department of Cardiovascular Medicine, Senior Resident
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2017.12-2019.12Washington University in St. Louis, Department of Developmental Biology, Research Associate
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2020.01-2023.09SUNY Upstate Medical University, Department of Pharmacology, Research Associate
Research Areas 【 display / non-display 】
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Genome biology
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Molecular biology
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Cardiology
Published Papers & Misc 【 display / non-display 】
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Norifumi Urao, Jinghua Liu, Kentaro Takahashi, Gayathri Ganesh. Hematopoietic Stem Cells in Wound Healing Response. Adv Wound Care (New Rochelle). 2022.11; 11 (11): 598-621. ( PubMed, DOI )
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Sherri M Biendarra-Tiegs, Sergey Yechikov, Bhupinder Shergill, Brittany Brumback, Kentaro Takahashi, Venktesh S Shirure, Ruth Estelle Gonzalez, Laura Houshmand, Denise Zhong, Kuo-Chan Weng, Jon Silva, Timothy W Smith, Stacey L Rentschler, Steven C George. An iPS-derived in vitro model of human atrial conduction. Physiol Rep. 2022.09; 10 (18): e15407. ( PubMed, DOI )
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Masahiro Yamazoe, Tetsuo Sasano, Kensuke Ihara, Kentaro Takahashi, Wakana Nakamura, Naomi Takahashi, Hiroaki Komuro, Satomi Hamada, Tetsushi Furukawa. Sparsely methylated mitochondrial cell free DNA released from cardiomyocytes contributes to systemic inflammatory response accompanied by atrial fibrillation. Sci Rep. 2021.03; 11 (1): 5837. ( PubMed, DOI )
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Catherine E Lipovsky, Jesus Jimenez, Qiusha Guo, Gang Li, Tiankai Yin, Stephanie C Hicks, Somya Bhatnagar, Kentaro Takahashi, David M Zhang, Brittany D Brumback, Uri Goldsztejn, Rangarajan D Nadadur, Carlos Perez-Cervantez, Ivan P Moskowitz, Shaopeng Liu, Bo Zhang, Stacey L Rentschler. Chamber-specific transcriptional responses in atrial fibrillation. JCI Insight. 2020.09; 5 (18): ( PubMed, DOI )
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Jiyoung Lee, Akito Sutani, Rin Kaneko, Jun Takeuchi, Tetsuo Sasano, Takashi Kohda, Kensuke Ihara, Kentaro Takahashi, Masahiro Yamazoe, Tomohiro Morio, Tetsushi Furukawa, Fumitoshi Ishino. In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix. Nat Commun. 2020.09; 11 (1): 4283. ( PubMed, DOI )
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Kiichi Yamamoto, Kentaro Takahashi, Manabu Ato, Shiroh Iwanaga, Nobuo Ohta. Antimalarial activity of vitamin D3 (VD3) does not result from VD3-induced antimicrobial agents including nitric oxide or cathelicidin. Exp Parasitol. 2019.06; 201 67-77. ( PubMed, DOI )
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Gang Li, Aditi Khandekar, Tiankai Yin, Stephanie C Hicks, Qiusha Guo, Kentaro Takahashi, Catherine E Lipovsky, Brittany D Brumback, Praveen K Rao, Carla J Weinheimer, Stacey L Rentschler. Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles. J Mol Cell Cardiol. 2018.10; 123 92-107. ( PubMed, DOI )
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Yu Natsume, Kasumi Oaku, Kentaro Takahashi, Wakana Nakamura, Ai Oono, Satomi Hamada, Masahiro Yamazoe, Kensuke Ihara, Takeshi Sasaki, Masahiko Goya, Kenzo Hirao, Tetsushi Furukawa, Tetsuo Sasano. Combined Analysis of Human and Experimental Murine Samples Identified Novel Circulating MicroRNAs as Biomarkers for Atrial Fibrillation. Circ J. 2018.03; 82 (4): 965-973. ( PubMed, DOI )
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Kensuke Ihara, Koji Sugiyama, Kentaro Takahashi, Masahiro Yamazoe, Tetsuo Sasano, Tetsushi Furukawa. Electrophysiological Assessment of Murine Atria with High-Resolution Optical Mapping. J Vis Exp. 2018.02; (132): ( PubMed, DOI )
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Kenji Yoshioka, Shunsuke Kuroda, Kentaro Takahashi, Tetsuo Sasano, Tetsushi Furukawa, Akihiko Matsumura. Calcification of joints and arteries with novel NT5E mutations with involvement of upper extremity arteries. Vasc Med. 2017.12; 22 (6): 541-543. ( PubMed, DOI )
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Koji Sugiyama, Tetsuo Sasano, Junko Kurokawa, Kentaro Takahashi, Tadashi Okamura, Norihiro Kato, Mitsuaki Isobe, Tetsushi Furukawa. Oxidative Stress Induced Ventricular Arrhythmia and Impairment of Cardiac Function in Nos1ap Deleted Mice. Int Heart J. 2016.05; 57 (3): 341-349. ( PubMed, DOI )
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Kentaro Takahashi, Tetsuo Sasano, Koji Sugiyama, Junko Kurokawa, Noriko Tamura, Yurie Soejima, Motoji Sawabe, Mitsuaki Isobe, Tetsushi Furukawa. High-fat diet increases vulnerability to atrial arrhythmia by conduction disturbance via miR-27b. J. Mol. Cell. Cardiol.. 2016.01; 90 38-46. ( PubMed, DOI )
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Kentaro Takahashi, Tsunekazu Kakuta, Taishi Yonetsu, Tetsumin Lee, Kenji Koura, Keiichi Hishikari, Tadashi Murai, Yoshito Iesaka, Mitsuaki Isobe. In vivo detection of lipid-rich plaque by using a 40-MHz intravascular ultrasound: a comparison with optical coherence tomography findings. Cardiovasc Interv Ther. 2013.10; 28 (4): 333-343. ( PubMed, DOI )
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Sasano T, Takahashi K, Sugiyama K. Gene therapy for cardiac arrhythmias Acta Cardiologica Sinica. 2013.03; 29 217-225.
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Tetsumin Lee, Tsunekazu Kakuta, Taishi Yonetsu, Kentaro Takahashi, Ginga Yamamoto, Yoshito Iesaka, Hideomi Fujiwara, Mitsuaki Isobe. Assessment of echo-attenuated plaque by optical coherence tomography and its impact on post-procedural creatine kinase-myocardial band elevation in elective stent implantation. JACC Cardiovasc Interv. 2011.05; 4 (5): 483-491. ( PubMed, DOI )
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Taishi Yonetsu, Tsunekazu Kakuta, Tetsumin Lee, Kentaro Takahashi, Naohiko Kawaguchi, Ginga Yamamoto, Kenji Koura, Keiichi Hishikari, Yoshito Iesaka, Hideomi Fujiwara, Mitsuaki Isobe. In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography. Eur. Heart J.. 2011.05; 32 (10): 1251-1259. ( PubMed, DOI )
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Taishi Yonetsu, Tsunekazu Kakuta, Tetsumin Lee, Kentaro Takahashi, Ginga Yamamoto, Yoshito Iesaka, Hideomi Fujiwara, Mitsuaki Isobe. Significance of postprocedural cardiac biomarker elevations in patients with elective stent implantation. Int. J. Cardiol.. 2011.02; 146 (3): 454-455. ( PubMed, DOI )
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Taishi Yonetsu, Tsunekazu Kakuta, Tetsumin Lee, Kentaro Takahashi, Ginga Yamamoto, Yoshito Iesaka, Hideomi Fujiwara, Mitsuaki Isobe. Impact of plaque morphology on creatine kinase-MB elevation in patients with elective stent implantation. Int J Cardiol. 2011.01; 146 (1): 80-85. ( PubMed, DOI )
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Taishi Yonetsu, Tsunekazu Kakuta, Tetsumin Lee, Kei Takayama, Ken Kakita, Taro Iwamoto, Naohiko Kawaguchi, Kentaro Takahashi, Ginga Yamamoto, Yoshito Iesaka, Hideomi Fujiwara, Mitsuaki Isobe. Assessment of acute injuries and chronic intimal thickening of the radial artery after transradial coronary intervention by optical coherence tomography. Eur. Heart J.. 2010.07; 31 (13): 1608-1615. ( PubMed, DOI )
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Chang-Xi Bai, Kentaro Takahashi, Haruko Masumiya, Tohru Sawanobori, Tetsushi Furukawa. Nitric oxide-dependent modulation of the delayed rectifier K+ current and the L-type Ca2+ current by ginsenoside Re, an ingredient of Panax ginseng, in guinea-pig cardiomyocytes. Br. J. Pharmacol.. 2004.06; 142 (3): 567-575. ( PubMed, DOI )