Personnel Information

写真a

HONDA Keiji


Job title

Assistant Professor

Birth date

1979

Laboratory Address

1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan

Laboratory Phone number

+81-3-5803-5308

Laboratory Fax number

+81-3-3813-2134

Mail Address

The inquiry by e-mail is 《here》

Research Areas, Keywords

inner ear, vestibular research
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Graduating School 【 display / non-display 】

  • The University of Tokyo, Faculty of Engineering, 2003.03, Graduated

  • Tokyo Medical and Dental University, Faculty of Medicine, 2007.03, Graduated

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Graduate School 【 display / non-display 】

  • Tokyo Medical and Dental University, Doctor's Course, 2014.03, Completed

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Campus Career 【 display / non-display 】

  • 2008.04
    -
    2009.03
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Trainee Resident
  • 2009.04
    -
    2009.06
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Sensory, Orthopedic, and Dematologic Medicine， Otorhinolaryngology， Resident
  • 2010.04
    -
    2014.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Cognitive and Behavioral Medicine， Otorhinolaryngology， Graduate Student
  • 2011.07
    -
    2013.07
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Sensory, Orthopedic, and Dematologic Medicine， Otorhinolaryngology， Senior Resident
  • 2017.12
    -
    2019.02
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Cognitive and Behavioral Medicine， Otorhinolaryngology， Visiting Lecturer
  • 2019.03
    -
    2019.10
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Sensory, Orthopedic, and Dematologic Medicine， Otorhinolaryngology， Assistant Professor
  • 2019.11
    -
    2021.09
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Sensory, Orthopedic, and Dematologic Medicine， Otorhinolaryngology， Assistant Professor
  • 2021.10
    -
    Now
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Clinical Medicine， Department of Sensory, Orthopaedic, and Dermatologic Medicine， Otorhinolaryngology， Assistant Professor

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External Career 【 display / non-display 】

  • 2007.04
    -
    2008.03
    , Trainee Resident
  • 2009.07
    -
    2011.06
    , Senior Resident
  • 2013.09
    -
    2016.08
    National Institute on Deafness and other Communication Disoders, Molecular Biology and Genetics Section, Visiting Fellow
  • 2016.09
    -
    2017.03
    , Senior Resident
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Research Areas 【 display / non-display 】

  • Molecular biology

  • Otorhinolaryngology

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Qualification Acquired 【 display / non-display 】

  • Doctor

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Published Papers & Misc 【 display / non-display 】

  1. Honda Keiji, Griffith Andrew J.. Genetic architecture and phenotypic landscape of SLC26A4-related hearing loss HUMAN GENETICS. 2021.08; 141 (3-4): 455-464. ( PubMed, DOI )

  2. Honda K, Lee HJ, Griffith AJ, Roux I. Dissection of the Endolymphatic Sac from Mice. Journal of visualized experiments : JoVE. 2021.03; (169): ( PubMed, DOI )

  3. Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ. Molecular architecture underlying fluid absorption by the developing inner ear. eLife. 2017.10; 6 ( PubMed, DOI )

  4. Honjo M, Honda K, Tsutsumi T. Unusual Vestibulo-Ocular Reflex Responses in Patients With Peripheral Vestibular Disorders Detected by the Caloric Step Stimulus Test. Frontiers in Neurology. 2020.11; 11 597562. ( PubMed, DOI )

  5. Chattaraj P, Munjal T, Honda K, Rendtorff ND, Ratay JS, Muskett JA, Risso DS, Roux I, Gertz EM, Schäffer AA, Friedman TB, Morell RJ, Tranebjærg L, Griffith AJ. A common SLC26A4-linked haplotype underlying non-syndromic hearing loss with enlargement of the vestibular aqueduct. Journal of medical genetics. 2017.10; 54 (10): 665-673. ( PubMed, DOI )

  6. Lee HJ, Fenollar-Ferrer C, Isgrig K, Wang YX, Valente K, Eide J, Honda K, Chien WW, Petralia RS, Dong L, Friedman TB, Bonifacino JS, Griffith AJ, Roux I. SLC26A4-AP-2 mu2 interaction regulates SLC26A4 plasma membrane abundance in the endolymphatic sac. Science advances. 2024.10; 10 (41): eadm8663. ( PubMed, DOI )

  7. Aoki N, Yamazaki A, Honda K, Tsutsumi T. Ocular torsion induced by Coriolis stimulation. Auris, nasus, larynx. 2024.08; 51 (4): 738-746. ( PubMed, DOI )

  8. Kondo, K; Inoue, N; Honda, K; Fushimi, K. Effectiveness of antibiotic therapy for early recurrence of peritonsillar cellulitis and abscesses: A retrospective cohort study AURIS NASUS LARYNX. 2024.06; 51 (3): 450-455. ( PubMed, DOI )

  9. Kondo, K; Honda, K; Goshima, K; Inoue, N; Shinjo, D; Tsutsumi, T; Fushimi, K. Otologic disease trends in Japan post-COVID-19 outbreak: A retrospective time-series analysis AURIS NASUS LARYNX. 2024.06; 51 (3): 525-530. ( PubMed, DOI )

  10. Mizoguchi, Y; Fujikawa, T; Kawashima, Y; Ito, T; Kitamura, K; Noguchi, Y; Takahashi, M; Honda, K; Takeda, T; Tsutsumi, T. High fluence in laser stapedotomy aggravates transient subjective dizziness ACTA OTO-LARYNGOLOGICA. 2024.02; 144 (2): 118-122. ( PubMed, DOI )

  11. Ito T, Watanabe H, Honda K, Fujikawa T, Kitamura K, Tsutsumi T. The role of SLC26A4 in bony labyrinth development and otoconial mineralization in mouse models. Frontiers in molecular neuroscience. 2024; 17 1384764. ( PubMed, DOI )

  12. Yamazaki A, Aoki N, Ooka T, Takeda T, Honda K, Yabunaka S, Tsutsumi T. Sustained deviation of torsional eye position associated with transient semicircular canal stimulation. Acta oto-laryngologica. 2023.10; 143 (10): 849-855. ( PubMed, DOI )

  13. Roux I, Fenollar-Ferrer C, Lee HJ, Chattaraj P, Lopez IA, Han K, Honda K, Brewer CC, Butman JA, Morell RJ, Martin DM, Griffith AJ. CHD7 variants associated with hearing loss and enlargement of the vestibular aqueduct. Human genetics. 2023.09; 142 (10): 1499-1517. ( PubMed, DOI )

  14. Kurata N, Kawashima Y, Ito T, Fujikawa T, Nishio A, Honda K, Kanai Y, Terasaki M, Endo I, Tsutsumi T. Advanced Magnetic Resonance Imaging Sheds Light on the Distinct Pathophysiology of Various Types of Acute Sensorineural Hearing Loss. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2023.08; 44 (7): 656-663. ( PubMed, DOI )

  15. Watanabe H, Ito T, Aoki N, Bai J, Honda K, Kawashima Y, Fujikawa T, Ikeda T, Tsutsumi T. Quantitative analysis and correlative evaluation of video-oculography, micro-computed tomography, and histopathology in Pendrin-null mice. Neurobiology of disease. 2023.07; 183 106194. ( PubMed, DOI )

  16. Bai Jing, Ito Taku, Fujikawa Taro, Honda Keiji, Kawashima Yoshiyuki, Watanabe Hiroki, Kurata Natsuko, Tsutsumi Takeshi. Three-dimensionally visualized ossification and mineralization process of the otic capsule in a postnatal developmental mouse LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY. 2023.06; 8 (4): 1036-1043. ( PubMed, DOI )

  17. Ooka Tomoki, Honda Keiji, Tsutsumi Takeshi. Static cervico-ocular reflex in healthy humans ACTA OTO-LARYNGOLOGICA. 2023.05; 143 (5): 387-391. ( PubMed, DOI )

  18. Fujikawa Taro, Tanimoto Kousuke, Kawashima Yoshiyuki, Ito Taku, Honda Keiji, Takeda Takamori, Sonobe Akane, Aoki Natsuki, Bai Jing, Tsutsumi Takeshi. Cholesteatoma has an altered microbiota with a higher abundance of Staphylococcus species LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY. 2022.12; 7 (6): 2011-2019. ( PubMed, DOI )

  19. Kondo, K; Kitagawa, T; Hata, Y; Fukuyama, K; Honda, K. Carotid artery dissection due to an elongated styloid process: A case report and implications for the otolaryngologist ACTA OTO-LARYNGOLOGICA CASE REPORTS. 2022.12; 7 (1): 78-80. ( DOI )

  20. Yamazaki Ayame, Ito Taku, Sugimoto Maki, Yoshida Soichiro, Honda Keiji, Kawashima Yoshiyuki, Fujikawa Taro, Fujii Yasuhisa, Tsutsumi Takeshi. Patient-specific virtual and mixed reality for immersive, experiential anatomy education and for surgical planning in temporal bone surgery(和訳中) Auris・Nasus・Larynx. 2021.12; 48 (6): 1081-1091. ( ichushi )

  21. Ito Taku, Fujikawa Taro, Honda Keiji, Makabe Ayane, Watanabe Hiroki, Bai Jing, Kawashima Yoshiyuki, Miwa Toru, Griffith Andrew J., Tsutsumi Takeshi. Cochlear Pathomorphogenesis of Incomplete Partition Type II in Slc26a4-Null Mice JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY. 2021.10; 22 (6): 681-691. ( PubMed, DOI )

  22. Yamaki Y, Hayashi D, Honda K, Imai H, Takada H. A case of omalizumab-associated eosinophilic granulomatosis with polyangiitis. Pediatrics international : official journal of the Japan Pediatric Society. 2021.09; 63 (9): 1119-1121. ( PubMed, DOI )

  23. Yamaki Yuni, Hayashi Daisuke, Honda Keiji, Imai Hironori, Takada Hidetoshi. オマリズマブ投与に伴う好酸球性多発血管炎性肉芽腫症の1例(A case of omalizumab-associated eosinophilic granulomatosis with polyangiitis) Pediatrics International. 2021.09; 63 (9): 1119-1121. ( ichushi )

  24. Yamazaki A, Ito T, Sugimoto M, Yoshida S, Honda K, Kawashima Y, Fujikawa T, Fujii Y, Tsutsumi T. Patient-specific virtual and mixed reality for immersive, experiential anatomy education and for surgical planning in temporal bone surgery. Auris, nasus, larynx. 2021.05; 48 (6): 1081-1091. ( PubMed, DOI )

  25. Aoki, N; Fujikawa, T; Umezawa, N; Kawashima, Y; Ito, T; Honda, K; Tsutsumi, T. 3-Tesla magnetic resonance imaging reveals vasculitis-caused otitis media in a patient with giant cell arteritis ACTA OTO-LARYNGOLOGICA CASE REPORTS. 2021; 6 (1): 6-10. ( DOI )

  26. Fujikawa Taro, Honda Keiji, Ito Taku, Kishino Mitsuhiro, Kimura Naoki, Umezawa Natsuka, Hirano Mana, Aoki Natsuki, Kawashima Yoshiyuki, Tsutsumi Takeshi. Enhanced fallopian canal as a potential marker for temporal bone vasculitis LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY. 2020.11; ( DOI )

  27. Ooka T, Bay J, Takeda T, Honda K, Ikeda T, Tsutsumi T. Clinical application of 3D-VOG analysis for quantitative evaluation of Otolith-Ocular reflex in the roll and pitch planes. Acta oto-laryngologica. 2020.10; 1-5. ( PubMed, DOI )

  28. Watanabe Hiroki, Makabe Ayane, Hirai Chiaki, Takeda Takamori, Honda Keiji, Demura Shinichi, Tsutsumi Takeshi. Frequency analyses of posturography using logarithmic translation ACTA OTO-LARYNGOLOGICA. 2020.01; 140 (1): 1-7. ( PubMed, DOI )

  29. Ito T, Kawashima Y, Fujikawa T, Honda K, Makabe A, Kitamura K, Tsutsumi T. Rapid screening of copy number variations in STRC by droplet digital PCR in patients with mild-to-moderate hearing loss. Human genome variation. 2019.08; 6 41. ( PubMed, DOI )

  30. Chao JR, Chattaraj P, Munjal T, Honda K, King KA, Zalewski CK, Chien WW, Brewer CC, Griffith AJ. SLC26A4-linked CEVA haplotype correlates with phenotype in patients with enlargement of the vestibular aqueduct. BMC medical genetics. 2019.07; 20 (1): 118. ( PubMed, DOI )

  31. Ito Taku, Kawashima Yoshiyuki, Fujikawa Taro, Honda Keiji, Makabe Ayane, Kitamura Ken, Tsutsumi Takeshi. 軽度～中等度難聴患者におけるドロプレットデジタルPCRを用いたSTRC遺伝子コピー数変化の迅速スクリーニング(Rapid screening of copy number variations in STRC by droplet digital PCR in patients with mild-to-moderate hearing loss) Human Genome Variation. 2019; 6 1 of 6-6 of 6. ( ichushi )

  32. Ozaki Kokoro, Ohkubo Takuya, Yamada Tetsuo, Yoshioka Kotaro, Ichijo Masahiko, Majima Takamasa, Kudo Shunsuke, Akashi Takumi, Honda Keiji, Ito Eisaku, Watanabe Mayumi, Sekine Masaki, Hamagaki Miwako, Eishi Yoshinobu, Sanjo Nobuo, Ishibashi Satoru, Mizusawa Hidehiro, Yokota Takanori. 胸腺摘出後に寛解を示し、後に全身浮腫を発症した筋硬直とミオクローヌスを伴う進行性脳脊髄炎　1剖検例(Progressive Encephalomyelitis with Rigidity and Myoclonus Resolving after Thymectomy with Subsequent Anasarca: An Autopsy Case) Internal Medicine. 2018.12; 57 (23): 3451-3458. ( ichushi )

  33. Ito T, Ikeda S, Asamori T, Honda K, Kawashima Y, Kitamura K, Suzuki K, Tsutsumi T. Increased expression of pendrin in eosinophilic chronic rhinosinusitis with nasal polyps. Brazilian journal of otorhinolaryngology. 2018.08; ( PubMed, DOI )

  34. Ozaki Kokoro, Ohkubo Takuya, Yamada Tetsuo, Yoshioka Kotaro, Ichijo Masahiko, Majima Takamasa, Kudo Shunsuke, Akashi Takumi, Honda Keiji, Ito Eisaku, Watanabe Mayumi, Sekine Masaki, Hamagaki Miwako, Eishi Yoshinobu, Sanjo Nobuo, Ishibashi Satoru, Mizusawa Hidehiro, Yokota Takanori. Progressive Encephalomyelitis with Rigidity and Myoclonus Resolving after Thymectomy with Subsequent Anasarca: An Autopsy Case INTERNAL MEDICINE. 2018.08; 57 (23): 3451-3458. ( PubMed, DOI )

  35. Honda K, Noguchi Y, Kawashima Y, Takahashi M, Nishio A, Kitamura K. Ex vivo visualization of the mouse otoconial layer compared with micro-computed tomography. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2015.02; 36 (2): 311-7. ( PubMed, DOI )

  36. Noguchi Y, Ito T, Nishio A, Honda K, Kitamura K. Audiovestibular findings in a branchio-oto syndrome patient with a SIX1 mutation. Acta oto-laryngologica. 2011.04; 131 (4): 413-8. ( PubMed, DOI )

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Books etc 【 display / non-display 】

  1. Griffith AJ and Honda K. 14 - Enlarged Vestibular Aqueduct In: Cummings Pediatric Otolaryngology (Second Edition), edited by M. M. Lesperance. 2021.08 (ISBN : 9780323696180)

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Conference Activities & Talks 【 display / non-display 】

  1. Tsutsumi Takeshi, Aoki Natsuki, Yamazaki Ayame, Takeda Takamori, Honda Keiji. ヘッドマウントディスプレイをベースとしたVOG装置の開発(Development of head mounted display-based VOG device). Equilibrium Research 2023.10.01

  2. 白 静, 伊藤 卓, 川島 慶之, 藤川 太郎, 本田 圭司, 渡邊 浩基, 倉田 奈都子, 堤 剛. C57BL/6Jマウスを用いた、出生後の耳石発生に関するEx VivoでのマイクロCT分析(Ex Vivo Micro-CT Analysis of Postnatal Otoconia Development in C57BL/6J Mice). 日本耳科学会総会・学術講演会抄録集 2022.10.01

  3. 白 静, 伊藤 卓, 川島 慶之, 藤川 太郎, 本田 圭司, 渡邊 浩基, 倉田 奈都子, 堤 剛. マウスの生後における耳嚢石灰化過程のマイクロCTによる可視化(Calcification Process of the Otic Capsule in Postnatal Stage of Mice Visualized with Micro-CT). 日本耳科学会総会・学術講演会抄録集 2021.10.01

  4. Tasaki Akihisa, Honda Keiji, Kamada Tomoko, Hatanaka Akio. 目の症状を伴うWegener肉芽腫症が疑われた1症例(A Suspected Case of Wegener's Granulomatosis with Ocular Symptom). 耳鼻咽喉科臨床 補冊 2014.03.01

  5. Tasaki Akihisa, Honda Keiji, Kamada Tomoko, Hatanaka Akio. 目の症状を伴うWegener肉芽腫症が疑われた1症例(A Suspected Case of Wegener's Granulomatosis with Ocular Symptom). 耳鼻咽喉科臨床 補冊 2014.03.01

  6. Tasaki Akihisa, Honda Keiji, Kamada Tomoko, Hatanaka Akio. 目の症状を伴うWegener肉芽腫症が疑われた1症例(A Suspected Case of Wegener's Granulomatosis with Ocular Symptom). 耳鼻咽喉科臨床 補冊 2014.03.01

  7. Tasaki Akihisa, Honda Keiji, Kamada Tomoko, Hatanaka Akio. 目の症状を伴うWegener肉芽腫症が疑われた1症例(A Suspected Case of Wegener's Granulomatosis with Ocular Symptom). 耳鼻咽喉科臨床 補冊 2014.03.01

  8. Tasaki Akihisa, Honda Keiji, Kamada Tomoko, Hatanaka Akio. 目の症状を伴うWegener肉芽腫症が疑われた1症例(A Suspected Case of Wegener's Granulomatosis with Ocular Symptom). 耳鼻咽喉科臨床 補冊 2014.03.01

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