Personnel Information

写真a

SHIBA Takahiko


Job title

Junior Associate Professor

Campus Career 【 display / non-display

  • 2010.04
    -
    2017.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Periodontology, Graduate Student
  • 2018.04
    -
    2019.08
    Tokyo Medical and Dental University, (Old Organization)Dental Hospital, Hospital Departments, Clinics for Conservation of Oral and Maxillofacial Function, Periodontics, Project Assistant Professor
  • 2019.10
    -
    2020.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Division of Bio-Matrix, Department of Periodontology, Visiting Lecturer
  • 2020.05
    -
    2020.09
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Division of Bio-Matrix, Department of Periodontology, Visiting Lecturer
  • 2020.10
    -
    2022.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Periodontology, Assistant Professor
  • 2022.04
    -
    2024.09
    Tokyo Medical and Dental University, Tokyo Medical and Dental University, Division of Clinical Dentistry, Department of Conservative Dentistry, Periodontics, Assistant Professor
  • 2024.10
    -
    2025.01
    Institute of Science Tokyo, -, Institute of Science Tokyo Hospital, Department of Conservative Dentistry, Periodontics, Assistant Professor
  • 2025.02
    -
    Now
    Institute of Science Tokyo, -, Graduate Schools, Bio-Matrix, Department of Periodontology, Junior Associate Professor

▼display all

 

Published Papers & Misc 【 display / non-display

  1. Shiba T, Takamori M, Katagiri S, Kobayashi R, Kawauchi A, Ohsugi Y, Lin P, Ekuni D, Egusa M, Iwata T, Maeda S.. Effects of Nonsurgical Periodontal Treatment on Bacterial and Clinical Parameters in Down Syndrome Patients Based on 16S rRNA Gene Amplicon Sequencing. Acta Medica Okayama. 2026.04; 80 (2): 85-97. ( PubMed, DOI )

  2. Ryota Kobayashi, Takahiko Shiba, Takahiko Nagai, Keiji Komatsu, Shunsuke Matsumura, Takayasu Watanabe, Takashi Nemoto, Koki Takada, Yasuo Takeuchi, Takanori Iwata. Metatranscriptomic insights into microbial network modulation and pathogen dynamics underlying healing outcomes in non-surgical periodontal treatment. ISME Commun. 2026.04; 6 (1): ycag092. ( PubMed, DOI )

  3. Takeuchi Y, Komatsu K, Nagai T, Kobayashi R, Nemoto T, Koyanagi T, Shiba T. Peri-Implantitis vs. Periodontitis : A Microbiological Perspective 口腔病学会雑誌. 2026.03; 93 (1): 2-9. ( DOI )

  4. Soma-Imai Chihiro, Ohsugi Yujin, Lin Peiya, Toyoshima Keita, Sekiguchi Mariko, Shiba Takahiko, Iwata Takanori, Uesaka Naofumi, Katagiri Sayaka. Differences in Composition of Oral and Gut Microbiome between Pre-pregnancy and during Lactation in Mice(タイトル和訳中) 口腔病学会雑誌. 2026.03; 93 (1): 20-30. ( ichushi )

  5. Daiane Fermiano, Eduardo de Souza Oliveira, Maria Josefa Mestnik, Luciene C Figueiredo, Takahiko Shiba, Shunsuke Matsumura, Edson de Sousa, Helio Doyle, Rafael Oliveira Dias, Marcelo de Faveri, Magda Feres. Does timing of systemic antibiotics influence periodontal treatment outcomes? A randomized clinical trial. J Periodontol. 2026.02; ( PubMed, DOI )

  6. Tomoaki Kariya, Chen-Yi Lee, Takahiko Shiba, David Minjoon Kim, Takanori Iwata. Single Buccal Envelope Flap with Connective Tissue Graft Wall and Fibroblast Growth Factor-2 Combined with Autogenous Bone Graft for Mandibular Class III Furcation Defect: A Case Report. Int J Periodontics Restorative Dent. 2025.12; 0 (0): 1-26. ( PubMed, DOI )

  7. Ho K, Shiba T, Chen CY, Kim DM. Plasma Treatment to Remove Titanium Surface Contaminants and Improve Implant Biocompatibility: An In Vitro Study. Biomimetics (Basel). 2025.08; 10 (9): ( PubMed, DOI )

  8. Masataka Arakawa, Koki Takada, Takahiko Shiba, Takahiko Nagai, Satoru Ogane, Tomoki Shimokawa, Sayaka Katagiri, Takanori Iwata, Ken Kozuma, Akihisa Kataoka. Blood Culture-Negative Infective Endocarditis Diagnosed via 16S rRNA Gene Amplicon Sequencing. JACC Case Rep. 2025.07; 30 (21): 104407. ( PubMed, DOI )

  9. Risako Mikami, Yasuo Takeuchi, Kazuyuki Ishihara, Yosuke Tsuchiya, Takahiko Nagai, Ryota Kobayashi, Takahiko Shiba, Takanori Iwata. Evaluation of Trypsin-Like Enzyme Activity Using a Novel Device for Monitoring Porphyromonas gingivalis in Periodontal Pockets: A Pilot Study. Cureus. 2025.05; 17 (5): e83832. ( PubMed, DOI )

  10. Latimer J, Yilmaz B, Feher B, Shiba T, Fretwurst T, Mitlak B, Lanske B, Kostenuik P, Giannobile WV. Abaloparatide Enhances Bone Regeneration in Extraction Socket Dental Implant Defects: An Experimental In Vivo Study. Clin Oral Implants Res. 2025.04; 36 (4): 471-480. ( PubMed, DOI )

  11. Kobayashi Ryota, Satake Kazuhisa, Nagai Takahiko, Matsumura Shunsuke, Takada Koki, Takeuchi Yasuo, Shiba Takahiko, Iwata Takanori. 16S rDNAアンプリコン配列決定法によって比較解析した、歯肉縁上および歯肉縁下の歯石内に存する細菌群集(Comparative Analysis of Bacterial Communities in Supragingival and Subgingival Calculus via 16S rDNA Amplicon Sequencing) 口腔病学会雑誌. 2025.03; 92 (1): 7-23. ( ichushi )

  12. João Gabriel S Souza, Fabio Azevedo, Maria Helena Rossy Borges, Raphael Cavalcante Costa, Takahiko Shiba, Shlomo Barak, Yaniv Mayer, Luciene Cristina de Figueiredo, Magda Feres, Valentim A R Barão, Jamil A Shibli. Microbiome modulation of implant-related infection by a novel miniaturized pulsed electromagnetic field device. NPJ Biofilms Microbiomes. 2025.02; 11 (1): 36. ( PubMed, DOI )

  13. Watanabe Keiichiro, Tanaka Eiji, Kamoi Kohei, Tichy Antonin, Shiba Takahiko, Yonerakura Kazuhide, Nakajima Masatoshi, Han Ruonan, Hosaka Keiichi. 欠損した下顎側切歯を生体模倣的に代替するため、3Dプリントしたフレキシブルインデックスを使って実施したコンポジットレジンの二重インジェクションモールド法(A dual composite resin injection molding technique with 3D-printed flexible indices for biomimetic replacement of a missing mandibular lateral incisor) Journal of Prosthodontic Research. 2024.10; 68 (4): 667-671. ( ichushi )

  14. Latimer, JM; Maekawa, S; Shiba, T; Fretwurst, T; Chen, MC; Larsson, L; Sugai, J; Kostenuik, P; Mitlak, B; Lanske, B; Giannobile, W. Healing sequelae following tooth extraction and dental implant placement in an aged, ovariectomy model JBMR PLUS. 2024.09; 8 (10): ziae113. ( PubMed, DOI )

  15. Latimer JM, Maekawa S, Shiba T, Fretwurst T, Chen M, Larsson L, Sugai JV, Kostenuik P, Mitlak B, Lanske B, Giannobile WV. Healing sequelae following tooth extraction and dental implant placement in an aged, ovariectomy model JBMR Plus. 2024.08;

  16. NAGAI Takahiko , SHIBA Takahiko , KOMATSU Keiji , MATSUMURA Shunsuke , KOYANAGI Tatsuro , NEMOTO Takashi , KOBAYASHI Ryota , TAKEUCHI Yasuo , IWATA Takanori. Characterizing Bacterial Communities among Healthy, Peri—implant Mucositis, and Peri—implantitis Statuses by 16S rRNA Gene Amplicon Sequencing The Journal of the Stomatological Society. 2024.03; 91 (1):

  17. Watanabe K, Tanaka E, Kamoi K, Tichy A, Shiba T, Yonerakura K, Nakajima M, Han R, Hosaka K. A dual composite resin injection molding technique with 3D-printed flexible indices for biomimetic replacement of a missing mandibular lateral incisor. J Prosthodont Res. 2024.03; ( PubMed, DOI )

  18. Yokose M, Komatsu K, Shiba T, Tanaka D, Takeuchi Y, Ikeda Y. Gnetin-C, a Resveratrol Dimer, Inhibits the Growth and Virulence of Porphyromonas gingivalis 口腔病学会雑誌. 2024.03; 91 (1): 47-65. ( ichushi )

  19. Takahiko Nagai, Takahiko Shiba, Keiji Komatsu, Shunsuke Matsumura, Tatsuro Koyanagi, Takashi Nemoto, Ryota Kobayashi, Yasuo Takeuchi, Takanori Iwata. Characterizing Bacterial Communities among Healthy, Peri-implant Mucositis, and Peri-implantitis Statuses by 16S rRNA gene amplicon sequencing 口腔病学会雑誌. 2024.03; 91 (1):

  20. Nagai Takahiko, Shiba Takahiko, Komatsu Keiji, Matsumura Shunsuke, Koyanagi Tatsuro, Nemoto Takashi, Kobayashi Ryota, Takeuchi Yasuo, Iwata Takanori. 健康なインプラント、インプラント周囲粘膜炎、インプラント周囲炎でみられる細菌群集の16S rRNA遺伝子アンプリコン配列解析による特性評価(Characterizing Bacterial Communities among Healthy, Peri-implant Mucositis, and Peri-implantitis Statuses by 16S rRNA Gene Amplicon Sequencing) 口腔病学会雑誌. 2024.03; 91 (1): 8-18. ( ichushi )

  21. Ishikawa H, Valdes L, Xie J, Ohyama H, Tate I, Maeno M, Shiba T, Nagai S. Learning from Mistakes—Dental Students’ Learning Experiences from Adverse Clinical Events Educ. Sci.. 2024.02;

  22. Shiba, T; Komatsu, K; Takeuchi, Y; Koyanagi, T; Taniguchi, Y; Takagi, T; Maekawa, S; Nagai, T; Kobayashi, R; Matsumura, S; Katagiri, S; Izumi, Y; Aoki, A; Iwata, T. Novel Flowchart Guiding the Non-Surgical and Surgical Management of Peri-Implant Complications: A Narrative Review BIOENGINEERING-BASEL. 2024.02; 11 (2): ( PubMed, DOI )

  23. Shiba T, Komatsu K, Takeuchi Y, Koyanagi T, Taniguchi Y, Takagi T, Maekawa S, Nagai T, Kobayashi R, Matsumura S, Katagiri S, Izumi Y, Aoki A, Iwata T. Novel flowchart guiding the non-surgical and surgical management of peri-implant complications: a narrative review Bioenginnering. 2024.01; 11 (2): 118.

  24. Lin P, Liu A, Tsuchiya Y, Noritake K, Ohsugi Y, Toyoshima K, Tsukahara Y, Shiba T, Nitta H, Aoki A, Iwata T, Katagiri S. Association between periodontal disease and chronic obstructive pulmonary disease Japanese Dental Science Review. 2023.12; 59 389-402. ( PubMed, DOI )

  25. Lin Peiya, Liu Anhao, Tsuchiya Yosuke, Noritake Kanako, Ohsugi Yujin, Toyoshima Keita, Tsukahara Yuta, Shiba Takahiko, Nitta Hiroshi, Aoki Akira, Iwata Takanori, Katagiri Sayaka. 歯周病と慢性閉塞性肺疾患の関連性(Association between periodontal disease and chronic obstructive pulmonary disease) The Japanese Dental Science Review. 2023.12; 59 389-402. ( ichushi )

  26. Keita Toyoshima, Yujin Ohsugi, Peiya Lin, Keiji Komatsu, Takahiko Shiba, Yasuo Takeuchi, Tomomitsu Hirota, Tsuyoshi Shimohira, Yosuke Tsuchiya, Sayaka Katagiri, Takanori Iwata, Akira Aoki. Blue Light-Emitting Diode Irradiation Without a Photosensitizer Alters Oral Microbiome Composition of Ligature-Induced Periodontitis in Mice. Photobiomodul Photomed Laser Surg. 2023.10; 41 (10): 549-559. ( PubMed, DOI )

  27. Katagiri S, Ohsugi Y, Shiba T, Yoshimi K, Nakagawa K, Nagasawa Y, Uchida A, Liu A, Lin P, Tsukahara Y, Iwata T, Tohara H. Homemade blenderized tube feeding improves gut microbiome communities in children with enteral nutrition Frontiers in Microbiology. 2023.08; 14 1215236.

  28. Shiba T, Komatsu K, Watanabe T, Takeuchi Y, Nemoto T, Ohsugi Y, Katagiri S, Shimogishi M, Marukawa E, Iwata T. Peri-implantitis management by resective surgery combined with implantoplasty and Er:YAG laser irradiation, accompanied by free gingival graft: a case report. Therapeutic advances in chronic disease. 2023.06; 14 20406223231174816. ( PubMed, DOI )

  29. Kataoka A, Shiba T, Katagiri S, Koyama S, Kito K, Ota T, Katayama T, Ohsugi Y, Nagai T, Kobayashi R, Komatsu K, Urata M, Imazuru T, Iwata T, Kozuma K. Novel and Efficient Method for Diagnosing Infective Endocarditis Using 16S Ribosomal RNA Gene Amplicon Sequence JACC Case Reports. 2023.04; 11 101793. ( PubMed, DOI )

  30. Nagasawa, Y; Katagiri, S; Nakagawa, K; Hirota, T; Yoshimi, K; Uchida, A; Hatasa, M; Komatsu, K; Shiba, T; Ohsugi, Y; Uesaka, N; Iwata, T; Tohara, H. Xanthan gum-based fluid thickener decreases postprandial blood glucose associated with increase of<i> Glp1</i> and<i> Glp1r</i> expression in ileum and alteration of gut microbiome JOURNAL OF FUNCTIONAL FOODS. 2022.12; 99 ( DOI )

  31. Nagasawa Y, Katagiri S, Nakagawa K, Hirota T, Yoshimi K, Uchida A, Hatasa M, Komatsu K, Shiba T, Ohsugi Y, Uesaka N, Iwata T, Tohara H. Xanthan gum-based fluid thickener decreases postprandial blood glucose associated with increase of Glp1 and Glp1r expression in ileum and alteration of gut microbiome Journal of Functional Foods. 2022.11;

  32. Ohsugi Y, Hatasa M, Katagiri S, Hirota T, Shimohira T, Shiba T, Komatsu K, Tsuchiya Y, Fukuba S, Lin P, Toyoshima K, Maekawa S, Niimi H, Iwata T, Aoki A. High-frequency pulsed diode laser irradiation inhibits bone resorption in mice with ligature-induced periodontitis Journal of Clinical Periodontology. 2022.07; e-pub (12): 1275-1288. ( PubMed, DOI )

  33. Shiba T, Katagiri S, Komatsu K, Nemoto T, Takeuchi Y, Chen B, Zhou YS, Iwata T. Treatment of peri-implantitis caused by malpositioning and an extra implant: a case report Int J Periodontics Restorative Dent. 2022.01; 42 (1): e15-e20. ( PubMed, DOI )

  34. Yoshida S, Hatasa M, Ohsugi Y, Tsuchiya Y, Liu A, Niimi H, Morita K, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Okano T, Hirose A, Ibi R, Noritake K, Tomiga Y, Nitta H, Suzuki T, Takahashi H, Miyasaka N, Iwata T, Katagiri S. Porphyromonas gingivalis administration induces gestational obesity, alters gene expression in the liver and brown adipose tissue in pregnant mice, and causes underweight in fetuses Frontiers in Cellular and Infection Microbiology. 2022.01; 11 745117. ( PubMed, DOI )

  35. Shimogishi M, Watanabe T, Shibasaki M, Shiba T, Komatsu K, Nemoto T, Ishihara K, Nakano Y, Iwata T, Kasugai S, Nakagawa I. Patient-specific establishment of bacterial composition within the peri-implant microbiota during the earliest weeks after implant uncovering. Journal of Periodontal Research. 2021.10; 56 (5): 964-971. ( PubMed, DOI )

  36. Nemoto T, Shiba T, Komatsu K, Watanabe T, Shimogishi M, Shibasaki M, Koyanagi T, Nagai T, Katagiri S, Takeuchi Y, Iwata T. Discrimination of bacterial community structures among healthy, gingivitis, and periodontitis statuses through integrated metatranscriptomic and network analyses. mSystems. 2021.10; 6 (6): e0088621. ( PubMed, DOI )

  37. Saida H, Fukuba S, Shiba T, Komatsu K, Iwata T, Nitta H. Two-stage approach for class II mandibular furcation defect with insufficient keratinized mucosa: a case report with 3 years' follow-up. The Journal of international medical research. 2021.09; 49 (9): 3000605211044595. ( PubMed, DOI )

  38. Lin P, Niimi H, Ohsugi Y, Tsuchiya Y, Shimohira T, Komatsu K, Liu A, Shiba T, Aoki A, Iwata T, Katagiri S. Application of Ligature-Induced Periodontitis in Mice to Explore the Molecular Mechanism of Periodontal Disease International Journal of Molecular Sciences. 2021.08; 22 (16): 8900. ( PubMed, DOI )

  39. Shimohira T, Niimi H, Ohsugi Y, Tsuchiya Y, Morita K, Yoshida S, Hatasa M, Shiba T, Kadokura H, Yokose S, Katagiri S, Iwata T, Aoki A. Low-Level Erbium-Doped Yttrium Aluminum Garnet Laser Irradiation Induced Alteration of Gene Expression in Osteogenic Cells from Rat Calvariae Photobiomodulation, Photobiomedicine, and Laser Surgery. 2021.07; ( DOI )

  40. Shiba T, Watanabe T, Komatsu K, Koyanagi T, Nemoto T, Ohsugi Y, Michi Y, Katagiri S, Takeuchi Y, Ishihara K, Iwata T. Non-surgical treatment for periodontitis and peri-implantitis: longitudinal clinical and bacteriological findings-A case report with a 7-year follow-up evaluation. SAGE open medical case reports. 2021.07; 9 2050313X211029154. ( PubMed, DOI )

  41. Yang J, Liu Q, Shiba T, Ji C, Iwata T, Jiang T. Application of digital prosthodontics and connective tissue grafting in the management of peri-implant mucosal recession around a malpositioned 1-piece implant: A clinical report. The Journal of prosthetic dentistry. 2021.05; 128 (6): 1145-1151. ( PubMed, DOI )

  42. Kataoka A, Katagiri S, Kawashima H, Nagura F, Nara Y, Hioki H, Nakashima M, Sasaki N, Hatasa M, Maekawa S, Ohsugi Y, Shiba T, Watanabe Y, Shimokawa T, Iwata T, Kozuma K. Association between Periodontal Bacteria and Degenerative Aortic Stenosis: A Pilot Study Journal of Periodontal and Implant Science. 2021.04; 51 (e9): 1-24.

  43. Hatasa M, Ohsugi Y, Katagiri S, Yoshida S, Niimi H, Morita K, Tsuchiya Y, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Tohara H, Takahashi H, Nitta H, Iwata T. Endotoxemia by Porphyromonas gingivalis alters endocrine functions in brown adipose tissue Frontiers in Cellular and Infection Microbiology. 2021.01; 19 (10): 580577.

  44. Komatsu K, Shiba T, Takeuchi Y, Watanabe T, Koyanagi T, Nemoto T, Shimogishi M, Shibasaki M, Katagiri S, Kasugai S, Iwata T. Discriminating Microbial Community Structure Between Peri-Implantitis and Periodontitis With Integrated Metagenomic, Metatranscriptomic, and Network Analysis Frontiers in Cellular and Infection Microbiology. 2020.12; 10 ( DOI )

  45. Watanabe K, Katagiri S, Takahashi H, Sasaki N, Maekawa S, Komazaki R, Hatasa M, Kitajima Y, Maruyama Y, Shiba T, Komatsu K, Ohsugi Y, Tanaka K, Matsuzawa A, Hirota T, Tohara H, Eguchi Y, Anzai K, Hattori A, Iwata T. Porphyromonas gingivalis impairs glucose uptake in skeletal muscle associated with altering gut microbiota The FASEB Journal. 2020.11; 35 (2): e21171. ( PubMed, DOI )

  46. Ikeda Eri, Shiba Takahiko, Ikeda Yuichi, Suda Wataru, Nakasato Akinori, Takeuchi Yasuo, Azuma Miyuki, Hattori Masahira, Izumi Yuichi. Japanese subgingival microbiota in health vs disease and their roles in predicted functions associated with periodontitis ODONTOLOGY. 2020.04; 108 (2): 280-291. ( PubMed, DOI )

  47. Ikeda Eri, Shiba Takahiko, Ikeda Yuichi, Suda Wataru, Nakasato Akinori, Takeuchi Yasuo, Azuma Miyuki, Hattori Masahira, Izumi Yuichi. 日本人の健康および病的状態にある歯肉縁下での微生物叢の比較ならびにその微生物叢が歯周炎に関連すると予測される機能において有する役割(Japanese subgingival microbiota in health vs disease and their roles in predicted functions associated with periodontitis) Odontology. 2020.04; 108 (2): 280-291. ( ichushi )

  48. Ogawa M, Katagiri S, Koyanagi T, Maekawa S, Shiba T, Ohsugi Y, Takeuchi Y, Ikawa T, Takeuchi S, Sekiuchi T, Arai Y, Kazama R, Wakabayashi N, Izumi Y, Iwata T. Accuracy of cone beam computed tomography in evaluation of palatal mucosa thickness. Journal of Clinical Periodontology. 2020.01; ( PubMed, DOI )

  49. Shiba T, Watanabe T. Polymicrobial Peri-Implant Infection Risk Factor for Peri-implant Diseases. 2020;

  50. Hatasa M, Ohsugi Y, Katagiri S, Yoshida S, Niimi H, Morita K, Tsuchiya Y, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Tohara H, Takahashi H, Nitta H, Iwata T.. Endotoxemia by Porphyromonas gingivalis alters endocrine functions in brown adipose tissue Frontiers in Cellular and Infection Microbiology. 2020; 10 580577. ( PubMed, DOI )

  51. Katagiri S, Shiba T, Tohara H, Yamaguchi K, Hara K, Nakagawa K, Komatsu K, Watanabe K, Ohsugi Y, Maekawa S, Iwata T. Re-initiation of Oral Food Intake Following Enteral Nutrition Alters Oral and Gut Microbiota Communities Frontiers in Cellular and Infection Microbiology. 2019.12; 9 434. ( PubMed, DOI )

  52. Watanabe K, Ohsugi Y, Maekawa S, Sasaki N, Shiba T, Katagiri S, Arakawa S. Ozone Ultrafine Bubble Water improves wound healing via modification of inflammation Journal of the Stomatological Societ. 2019.07; 86 (2): 25-34.

  53. 渡辺 数基, 大杉 勇人, 前川 祥吾, 佐々木 直樹, 芝 多佳彦, 片桐 さやか, 荒川 真一. 創傷治癒モデルマウスにおける炎症因子を介したオゾンウルトラファインバブル水の効果(Ozone Ultrafine Bubble Water Improves Wound Healing via Modification of Inflammation) 口腔病学会雑誌. 2019.07; 86 (2): 25-35. ( ichushi )

  54. Ohtsu Anri, Takeuchi Yasuo, Katagiri Sayaka, Suda Wataru, Maekawa Shogo, Shiba Takahiko, Komazaki Rina, Udagawa Sayuri, Sasaki Naoki, Hattori Masahira, Izumi Yuichi. Influence of Porphyromonas gingivalis in gut microbiota of streptozotocin-induced diabetic mice ORAL DISEASES. 2019.04; 25 (3): 868-880. ( PubMed, DOI )

  55. Funahashi Kenta, Shiba Takahiko, Watanabe Takayasu, Muramoto Keiko, Takeuchi Yasuo, Ogawa Takuya, Izumi Yuichi, Sekizaki Tsutomu, Nakagawa Ichiro, Moriyama Keiji. Functional dysbiosis within dental plaque microbiota in cleft lip and palate patients PROGRESS IN ORTHODONTICS. 2019.03; 20 (1): 11. ( PubMed, DOI )

  56. Ikeda E, Shiba T, Ikeda Y, Suda W, Nakasato A, Takeuchi Y, Azuma M, Hattori M, Izumi Y. Deep sequencing reveals specific bacterial signatures in the subgingival microbiota of healthy subjects. Clinical oral investigations. 2019.01; e-pub ( PubMed, DOI )

  57. Sasaki Naoki, Katagiri Sayaka, Komazaki Rina, Watanabe Kazuki, Maekawa Shogo, Shiba Takahiko, Udagawa Sayuri, Takeuchi Yasuo, Ohtsu Ann, Kohda Takashi, Tohara Haruka, Miyasaka Naoyuki, Hirota Tomomitsu, Tamari Mayumi, Izumi Yuichi. Endotoxemia by Porphyromonas gingivalis Injection Aggravates Non-alcoholic Fatty Liver Disease, Disrupts Glucose/Lipid Metabolism, and Alters Gut Microbiota in Mice FRONTIERS IN MICROBIOLOGY. 2018.10; 9 2470. ( PubMed, DOI )

  58. Komazaki R, Katagiri S, Takahashi H, Maekawa S, Shiba T, Takeuchi Y, Kitajima Y, Ohtsu A, Udagawa S, Sasaki N, Watanabe K, Sato N, Miyasaka N, Eguchi Y, Anzai K, Izumi Y. Author Correction: Periodontal pathogenic bacteria, Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolism. Scientific reports. 2018.03; 8 (1): 4620. ( PubMed, DOI )

  59. Udagawa S, Katagiri S, Maekawa S, Takeuchi Y, Komazaki R, Ohtsu A, Sasaki N, Shiba T, Watanabe K, Ishihara K, Sato N, Miyasaka N, Izumi Y. Effect of Porphyromonas gingivalis infection in the placenta and umbilical cord in pregnant mice with low birth weight. Acta Odontologica Scandinavica. 2018.01; 1-9. ( PubMed, DOI )

  60. Rina Komazaki, Sayaka Katagiri, Hirokazu Takahashi, Shogo Maekawa, Takahiko Shiba, Yasuo Takeuchi, Yoichiro Kitajima, Anri Ohtsu, Sayuri Udagawa, Naoki Sasaki, Kazuki Watanabe, Noriko Sato, Naoyuki Miyasaka, Yuichiro Eguchi, Keizo Anzai, Yuichi Izumi. Periodontal pathogenic bacteria, Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolism Scientific Reports. 2017.10;

  61. Kachi H, Maruyama N, Maruyama F, Shiba T, Watanabe T, Goda A, Murase K, Michi Y, Takeuchi Y, Izumi Y, Harada K, Nakagawa I. Active microbiota show specific correlationships in peri-implantitis and periodontitis. 口腔病学会雑誌. 2017.03; 84 (1): 25-36.

  62. 加地 博一, 丸山 緑子, 丸山 史人, 芝 多佳彦, 渡辺 孝康, 郷田 瑛, 村瀬 一典, 道 泰之, 竹内 康雄, 和泉 雄一, 山口 聰, 中川 一路. 細菌活動性から顕在化するインプラント周囲炎および歯周炎の疾患特異的な細菌群集内の共起構造(Active Microbiota Show Specific Correlationships in Peri-implantitis and Periodontitis) 口腔病学会雑誌. 2017.03; 84 (1): 25-36. ( ichushi )

  63. Shiba T, Watanabe T, Kachi H, Koyanagi T, Maruyama N, Murase K, Takeuchi Y, Maruyama F, Izumi Y, Nakagawa I. Distinct interacting core taxa in co-occurrence networks enable discrimination of polymicrobial oral diseases with similar symptoms. Sci Rep. 2016.08; 6 30997. ( PubMed, DOI )

▼display all

Conference Activities & Talks 【 display / non-display

  1. Isabel Tate, Alex Mio Nishio Weinberger, Akiko Asano, Masahiko Maeno, Yukinori Kuwajima, Yoshiki Ishida, Takahiko Shiba, Arafumi Ohash, Daisuke Sasaki, Shigemi Nagai. Shadowing Experience Among Japanese Dental Students Compared to U.S. Standards. 2026.03.25 SAN DIEGO, CA, USA

  2. Takahiko Nagai, Risako Mikami, Yasuo Takeuchi, Kazuyuki Ishihara, Yusuke Tsuchiya, Ryota Kobayashi, Takahiko Shiba, Takanori Iwata. Evaluation of Trypsin-Like Protease Activity in Periodontal Pockets. 2026 IADR/AADOCR/CADR General Session & Exhibition 2026.03.25

  3. Matsumura S, Shiba T, Anzai T, Nagai T, Komatsu K, Kobayashi R, Takada K, Satake K, Takeuchi Y, Iwata T. Development and Optimization of a Machine Learning-Based Diagnostic Model for Peri-Implantitis Using 16S rDNA Sequencing Data . AAP 111th annual conference 2025.10 Toronto

  4. Lin Peiya, Ohsugi Yujin, Okano Tokuju, Imai Chihiro, Toyoshima Keita, Shiba Takahiko, Nagai Shigenori, Suzuki Toshihiko, Katagiri Sayaka. 次世代シークエンサーを用いて調査した歯周炎と関節リウマチの関連性(Investigating the relationship between periodontitis and rheumatoid arthritis using next-generation sequencer). 口腔病学会雑誌 2025.03.01

  5. Koki Takada, Takahiko Shiba, Takahiko Nagai, Ryota Kobayashi, Shunsuke Matsumura, Keiji Komatsu, Sayaka Katagiri, Takanori Iwata . Exploring the Relationship between Oral Bacteria and Infective Endocarditis through Next-Generation Sequencing. 口腔病学会 2024.12.06

  6. Nagai Takahiko, Shiba Takahiko, Komatsu Keiji, Matsumura Shunsuke, Koyanagi Tatsuro, Nemoto Takashi, Kobayashi Ryota, Takada Koki, Takeuchi Yasuo, Iwata Takanori. 健常部位、インプラント周囲粘膜炎部位およびインプラント周囲炎部位における細菌組成の特徴(Characteristics of Bacterial Communities among Healthy, Peri-implant Mucositis, and Peri-implantitis Statuses). 日本歯周病学会会誌 2024.12.01

  7. Imai Chihiro, Katagiri Sayaka, Ohsugi Yujin, Lin Peiya, Toyoshima Keita, Hirota Tomomitsu, Shiba Takahiko, Uesaka Naofumi, Iwata Takanori. 母胎における歯牙結紮によって誘導された歯周炎が仔の脳に及ぼす影響(Effects of maternal ligature-induced periodontitis on brain in offsprings). 日本歯周病学会会誌 2024.12.01

  8. Kobayashi Ryota, Shiba Takahiko, Komatsu Keiji, Nemoto Takashi, Nagai Takahiko, Matsumura Shunsuke, Takada Koki, Takeuchi Yasuo, Iwata Takanori. 各種歯周病状態における非外科的治療後のマイクロバイオームの変化(Shifting the Microbiome Following Non-Surgical Treatment for Each Periodontal Status). 日本歯周病学会会誌 2024.12.01

  9. Lin Peiya, Tsuyoshi Shimohira, Yujin Ohsugi, Takahiko Shiba, Tomomitsu Hirota, Sayaka Katagiri, Akira Aoki. Effect of near-infrared phototherapy on medication-related osteonecrosis of the jaw in mice. The 18th Congress of World Federation for Laser Dentistry 2024.11.11 The Rebouças Convention Center

  10. Ryota Kobayashi, Takahiko Shiba, Takahiko Nagai, Keiji Komatsu, Shunsuke Matsumura, Takashi Nemoto, Koki Takada, Yasuo Takeuchi, Takanori Iwata. Shifting the Microbiome Following Non-Surgical Treatment for Each Periodontal Status. The 110th Annual Meeting of the American Academy of Periodontology 2024.11.06

  11. Takahiko Nagai1, Takahiko Shiba1, Keiji Komatsu2, Shunsuke Matsumura1, Tatsuro Koyanagi1, Takashi Nemoto, Ryota Kobayashi, Yasuo Takeuchi, Takanori Iwata. Characterizing Bacterial Communities among Healthy, Peri-implant Mucositis, and Peri-implantitis Statuses by 16S rRNA gene amplicon sequencing.. American Academy of Periodontology, 110th ANNUAL MEETING 2024.10.31

  12. Shiba T, Pereira da Silva HD, Figueiredo LC, Duarte P, de Souza Oliveira EH, Feres M. Analyzing Bacterial Network Dynamics in Periodontitis, Before and After Treatment. International Association for Dental Research General Session & Exhibition 2024.03.14 New Orleans, USA

  13. Ho K, Chen CY, Shiba T, Kim DM. Plasma Treatment Removes Implant Surface Contaminants and Improves Biocompatibility. Academy of Osseointegrartion 2024.03.07 Charlotte, USA

  14. Shiba T, Ho K, Cho YWS, Chen CY, Kim DM. Effect of Er,Cr:YSGG laser irradiation on the surface modification and cell adhesion on titanium discs: an in vitro study. Academy of Osseointegration 2024.03.07 Charlotte, USA

  15. Nagai Takahiko, Shiba Takahiko, Komatsu Keiji, Takashi Nemoto, Kobayashi Ryota, Takeuchi Yasuo, Iwata Takanori. 口腔内細菌叢のシークエンス解析に適したアプローチの決定(Determining the best approach for sequencing analysis of oral microbiota). 日本歯周病学会会誌 2022.12.01

  16. 下平 剛, 大杉勇人, 片桐さやか, 芝多佳彦, 駒津匡二, 劉 安豪, 林 培雅, 豊嶋啓汰, 青木 章. 近赤外線光線療法の薬剤関連性顎骨壊死への応用と分子機構の解明. 第64回歯科基礎医学会学術大会 2022.09.17 徳島

  17. Shimohira T, Niimi H, Ohsugi Y, Tsuchiya Y, Morita K, Yoshida S, Hatasa M, Shiba T, Kadokura H, Yokose S, Katagiri S, Iwata T, Aoki A. . Low-level Er:YAG laser irradiation induced alteration of gene expression in rat calvarial osteogenic cells. Dental Laser Virtual Scientific Conference 2021 2021.07.16

  18. Katagiri Sayaka, Watanabe Kazuki, Maekawa Shogo, Hatasa Masahiro, Shiba Takahiko, Komatsu Keiji, Ohsugi Yujin, Tohara Haruka, Iwata Takanori. Porphyromonas gingivalisは腸内細菌叢を変化させ、それに伴って骨格筋でのグルコース取り込みを障害する(Porphyromonas gingivalis impairs glucose uptake in skeletal muscle associated with altering gut microbiota). 口腔病学会雑誌 2021.03.01

  19. Komatsu Keiji, Shiba Takahiko, Watanabe Takayasu, Nemoto Takashi, Koyanagi Tatsuro, Takeuchi Yasuo, Iwata Takanori. 歯周炎およびインプラント周囲炎の非外科的治療法と細菌叢の分析 7年間の経過観察結果(Non-surgical treatment and microbiome of periodontitis and peri-implantitis: seven-year follow-up). 日本歯周病学会会誌 2020.12.01

  20. Keiji Komatsu, Yasuo Takeuchi, Takahiko Shiba, Takayasu Watanabe, Masahiro Shimogishi, Masaki Shibasaki, Takashi Nemoto Tatsuro Koyanagi, Sayaka Katagiri, Takanori Iwata. Omics analysis defines differences in microbial community structure between peri-implantitis and periodontitis. 第68回国際歯科研究学会日本部会 総会・学術大会 2020.11.07 Virtual

  21. Keiji Komatsu, Takahiko Shiba, Takayasu Watanabe, Takashi Nemoto, Tatsuro Koyanagi, Takanori Iwata. Non-surgical treatment and microbiome of periodontitis and peri-implantitis: seven-year. The 106th Annual Meeting of the American Academy of Periodontology in collaboration with the Japanese Society of Periodontology and Japanese Academy of Clinical Periodontology 2020.11.06 Virtual

  22. Katagiri Sayaka, Shiba Takahiko, Tohara Haruka, Yamaguchi Kohei, Hara Koji, Nakagawa Kazuharu, Komatsu Keiji, Watanabe Kazuki, Ohsugi Yujin, Maekawa Shogo, Iwata Takanori. 経腸栄養後の経口食物摂取の再開は口腔と腸内の細菌叢を変化させる(Re-initiation of oral food intake following enteral nutrition alters oral and gut microbiota communities). 口腔病学会雑誌 2020.03.01

  23. 2. Katagiri S, Shiba T, Tohara H, Yamaguchi K, Hara K, Nakagawa K, Komatsu K, Watanabe K, Ohsugi Y, Maekawa S, Iwata T. Re-initiation of oral food intake following enteral nutrian alters oral and gut microbiota communities.. 第83回口腔病学会学術大会 2019.12.07

  24. Tournadre C, Gritsch K, Takagi T, Shiba T, Mizutani K , Aoki A, Grosgogeat B. Cleaning potential of five different methods for peri-implantitis treatment: an in-vitro study. EAO’s 28th annual scientific meeting 2019.09.26 Congress center of Lisbon, Portugal

  25. Shiba T. Evaluation of core microbiome and clinical approach in peri-implantitis.. Dentiste Expo 2019.06.20

  26. 15. Sasaki N, Katagiri S, Maekawa S, Shiba T, Takeuchi Y, Ohtsu A, Izumi Y. Endotoxemia by Porphyromonas gingivalis injection aggravates non-alcoholic fatty liver disease, disrupts glucose/lipid metabolism, and alters gut microbiota in mice.. 第83回口腔病学術大会 2018.11.30

  27. 芝 多佳彦. インプラント周囲疾患を対象としたトランスオミックス解析. 第8回湯島若手塾 2018.11.19

  28. Naoki Sasaki, Sayaka Katagiri, Rina Komazaki, Kazuki Watanabe, Shogo Maekawa, Takahiko Shiba, Yasuo Takeuchi, Anri Ohtsu, Yuichi Izumi . Endotoxemia by Porphyromonas gingivalis injection aggravates non-alcoholic fatty liver disease, disrupts glucose/lipid metabolism, and alters gut microbiota in mice. 日本歯科保存学会2018年秋季学術大会 2018.11.02 京都

  29. Shiba T, Takagi T, Koyanagi T, et al.. The clinical application of the novel diagnosis and treatment flowchart for peri-implantitis: Part 1 clinical application to mild case. EuroPerio9 2018.06.20 Amsterdam, Holland.

  30. Taniguchi Y, Tatsuro K, Izumi Y, et al.. The clinical application of the novel diagnosis and treatment flowchart for peri-implantitis: Part 3 clinical application on severe case. EuroPerio9 2018.06.20 Amsterdam, Holland.

  31. Koyanagi T, Taniguchi Y, Izumi Y, et al.. The clinical application of a novel diagnosis and treatment flowchart for peri-implantitis: Part 2 - application to moderate cases . EuroPerio9 2018.06.20 Amsterdam, Holland.

  32. 24. Sasaki N, Katagiri S, Komazaki R, Watanabe K, Maekawa S, Shiba T, Udagawa S, Takeuchi Y, Ohtsu A, Kohda T, Tohara H, Miyasaka N, Hirota T, Tamari M, Izumi Y. Sonicated Porphyromonas gingvalis affect non-alcoholic fatty liver disease via glucose metabolism. 9th Conference of the European Federation of Periodontology. 2018.06.20

  33. Katagiri S, Komazaki R, Takahashi H, Maekawa S, Shiba T, Takeuchi Y, Kitajima Y, Ohtsu A, Udagawa S, Sasaki N, Watanabe K, Sato N, Miyasaka N, Eguchi Y, Anzai K, Izumi Y. Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolis.. The 103rd Annual Meeting of American Academy of Periodontology 2017.09.10 Boston, USA

  34. Shiba T, Watanabe T, Koyanagi T, Maruyama N, Takeuchi Y, Maruyama F, Izumi Y, Nakagawa I. Functional keystone species enable discrimination of peri-implantitis and periodontitis. The 102nd Annual Meeting of the American Academy of Periodontology 2016.09.10 San Diego, USA

  35. 渡辺孝康, 芝 多佳彦, 加地博一, 竹内康雄, 丸山史人, 和泉雄一, 中川一路. インプラント周囲炎と歯周炎における細菌叢メタトランスクリプトーム解析. 第58回歯科基礎医学会学術大会 2016.08.25 札幌

  36. Shiba T, Watanabe T, Maruyama F, Takeuchi Y, Koyanagi T, Maruyama N, Nakagawa I, Izumi Y. Inconsistency between abundance of 16S rRNA and mRNA in bacterial community of periodontitis and peri-implantitis. 8th Conference of the European Federation of Periodontology 2015.06.04 London, United Kingdom 2015.06.04

  37. Shiba T, Takeuchi Y, Maruyama F, Maruyama N, Koyanagi T, Nakagawa I, Izumi Y. Selection of microbial species and functional gene causing Peri-implantitis of active microbial communities.. The 78th Annual Meeting of Stomatological Society 2013.12.07

▼display all

Others 【 display / non-display

  • Drilling into the dental secrets of Edo-era Japanese bacterial genomes,2021.12

  • That's so meta(transcriptomics): distinctive bacterial taxonomic and functional profiles in mouth disease,2021.12