Personnel Information

写真a

AKUTSU Yuko


Job title

Project Assistant Professor
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Graduating School 【 display / non-display 】

  • Tokyo Medical and Dental University, Graduated

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Campus Career 【 display / non-display 】

  • 2019.04
    -
    2019.10
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Pediatrics, Maternal and Woman's Medicine， Pediatrics， Assistant Professor
  • 2019.11
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    2020.03
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Pediatrics, Maternal and Woman's Medicine， Pediatrics， Assistant Professor
  • 2020.04
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    2024.09
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Bio-Environmental Response， Department of Pediatrics and Developmental Biology， Graduate Student
  • 2024.10
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    2025.03
    Institute of Science Tokyo， -， Graduate Schools， Bio-Environmental Response， Department of Pediatrics and Developmental Biology， Graduate Student
  • 2025.04
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    Now
    Institute of Science Tokyo， -， Institute of Science Tokyo Hospital， Health Science Research and Development Center， Project Assistant Professor
  • 2025.04
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    Now
    Institute of Science Tokyo， -， Graduate Schools， Bio-Environmental Response， Department of Pediatrics and Developmental Biology， Project Assistant Professor

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Published Papers & Misc 【 display / non-display 】

  1. Masaki Shimizu, Shuya Kaneko, Asami Shimbo, Maho Hatano, Futaba Miyaoka, Yuko Hayashi, Hitoshi Irabu, Yuko Akutsu, Masaaki Mori. Distinct expression profiles of inflammasome-associated genes in systemic juvenile idiopathic arthritis. Rheumatology (Oxford). 2025.10; ( PubMed, DOI )

  2. Futaba Miyaoka, Hitoshi Irabu, Shuya Kaneko, Tomoya Kaneda, Yuko Akutsu, Yuko Hayashi, Masaki Shimizu. Diverse Joint Manifestations in Anti-MDA5 Antibody-Positive Juvenile Dermatomyositis: A Unique Case Report. Int J Rheum Dis. 2025.10; 28 (10): e70442. ( PubMed, DOI )

  3. Yuko Hayashi, Maho Hatano, Shuya Kaneko, Asami Shimbo, Hitoshi Irabu, Yuko Akutsu, Masaaki Mori, Masaki Shimizu. Clinical Outcomes After SARS-CoV-2 Infection and Vaccination in Patients With Pediatric Rheumatic Diseases. Int J Rheum Dis. 2025.08; 28 (8): e70394. ( PubMed, DOI )

  4. Asami Shimbo, Shuya Kaneko, Hitoshi Irabu, Yuko Akutsu, Yuko Hayashi, Mariko Mouri, Susumu Yamazaki, Masaaki Mori, Masaki Shimizu. Efficacy of hydroxychloroquine treatment for the skin manifestations of juvenile dermatomyositis. Mod Rheumatol Case Rep. 2025.07; 9 (2): ( PubMed, DOI )

  5. Masaki Shmizu, Shuya Kaneko, Asami Shimbo, Maho Hatano, Futaba Miyaoka, Hitoshi Irabu, Yuko Akutsu, Yuko Hayashi, Keiji Akamine, Masaaki Mori. Anifrolumab for refractory cutaneous lupus lesions in pediatric systemic lupus erythematosus. Lupus. 2025.04; 34 (5): 533-536. ( PubMed, DOI )

  6. Akutsu, Y; Ota, M; Itamiya, T; Mori, M; Morio, T; Yamamoto, K; Okamura, T; Fujio, K. Effect of Epstein-Barr Virus infection on gene regulation in immune cells of patients with Immune-Mediated Diseases JOURNAL OF AUTOIMMUNITY. 2025.01; 150 103355. ( PubMed, DOI )

  7. Yuko Akutsu, Asami Shimbo, Masaaki Mori, Masaki Shimizu. Juvenile idiopathic arthritis associated with Kabuki syndrome: A case report. Pediatr Int. 2025; 67 (1): e70261. ( PubMed, DOI )

  8. Akutsu Yuko, Shimbo Asami, Mori Masaaki, Shimizu Masaki. Juvenile idiopathic arthritis associated with Kabuki syndrome: A case report(タイトル和訳中) Pediatrics International. 2025; 67 (1): ped.70261. ( ichushi )

  9. Miyaoka, F; Hatano, M; Hayashi, Y; Kaneko, S; Shimbo, A; Irabu, H; Akutsu, Y; Segawa, Y; Mori, M; Shimizu, M. Atlantoaxial arthritis is more common in polyarticular JIA as compared to systemic onset JIA-Retrospective study INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES. 2024.11; 27 (11): e15396. ( PubMed, DOI )

  10. Mineto Ota, Masahiro Nakano, Yasuo Nagafuchi, Satomi Kobayashi, Hiroaki Hatano, Ryochi Yoshida, Yuko Akutsu, Takahiro Itamiya, Nobuhiro Ban, Yumi Tsuchida, Hirofumi Shoda, Kazuhiko Yamamoto, Kazuyoshi Ishigaki, Tomohisa Okamura, Keishi Fujio. Multimodal repertoire analysis unveils B cell biology in immune-mediated diseases. Ann Rheum Dis. 2023.11; 82 (11): 1455-1463. ( PubMed, DOI )

  11. Yamazaki, S; Shimbo, A; Akutsu, Y; Takase, H; Morio, T; Mori, M. Importance of pediatric rheumatologists and transitional care for juvenile idiopathic arthritis-associated uveitis: a retrospective series of 9 cases (vol 18, 26, 2020) PEDIATRIC RHEUMATOLOGY. 2023.10; 21 (1): 132. ( PubMed, DOI )

  12. Narazaki Hidehiko, Akioka Shinji, Akutsu Yuko, Araki Mariko, Fujieda Mikiya, Fukuhara Daisuke, Hara Ryoki, Hashimoto Kunio, Hattori Seira, Hayashibe Ren, Imagawa Tomoyuki, Inoue Yuzaburo, Ishida Hiroyuki, Ito Shuici, Itoh Yasuhiko, Kawabe Tomohiro, Kitoh Toshiyuki, Kobayashi Ichiro, Matsubayashi Tadashi, Miyamae Takako, Mizuta Mao, Mori Masaaki, Murase Ayako, Nakagishi Yasuo, Nagatani Koji, Nakano Naoko, Nishimura Toyoki, Nozawa Tomo, Okamoto Nami, Okura Yuka, Sawada Hiromi, Sawanobori Emi, Sugita Yuko, Tanabe Yujiro, Tomiita Minako, Yamaguchi Ken-ichi, Yasuoka Ryuhei, Yokoyama Koji. 日本小児リウマチ学会の登録データベースにもとづく小児リウマチ性疾患の疫学(Epidemiology conduction of paediatric rheumatic diseases based on the registry database of the Pediatric Rheumatology Association of Japan) Modern Rheumatology. 2023.09; 33 (5): 1021-1029. ( ichushi )

  13. Narazaki, H; Akioka, S; Akutsu, Y; Araki, M; Fujieda, M; Fukuhara, D; Hara, R; Hashimoto, K; Hattori, S; Hayashibe, R; Imagawa, T; Inoue, Y; Ishida, H; Ito, S; Itoh, Y; Kawabe, T; Kitoh, T; Kobayashi, I; Matsubayashi, T; Miyamae, T; Mizuta, M; Mori, M; Murase, A; Nakagishi, Y; Nagatani, K; Nakano, N; Nishimura, T; Nozawa, T; Okamoto, N; Okura, Y; Sawada, H; Sawanobori, E; Sugita, Y; Tanabe, Y; Tomiita, M; Yamaguchi, KI; Yasuoka, R; Yokoyama, K. Epidemiology conduction of paediatric rheumatic diseases based on the registry database of the Pediatric Rheumatology Association of Japan MODERN RHEUMATOLOGY. 2023.08; 33 (5): 1021-1029. ( PubMed, DOI )

  14. Masahiro Nakano, Mineto Ota, Yusuke Takeshima, Yukiko Iwasaki, Hiroaki Hatano, Yasuo Nagafuchi, Takahiro Itamiya, Junko Maeda, Ryochi Yoshida, Saeko Yamada, Aya Nishiwaki, Haruka Takahashi, Hideyuki Takahashi, Yuko Akutsu, Takeshi Kusuda, Hiroyuki Suetsugu, Lu Liu, Kwangwoo Kim, Xianyong Yin, So-Young Bang, Yong Cui, Hye-Soon Lee, Hirofumi Shoda, Xuejun Zhang, Sang-Cheol Bae, Chikashi Terao, Kazuhiko Yamamoto, Tomohisa Okamura, Kazuyoshi Ishigaki, Keishi Fujio. Distinct transcriptome architectures underlying lupus establishment and exacerbation. Cell. 2022.09; 185 (18): 3375-3389.e21. ( PubMed, DOI )

  15. Yamazaki, S; Shimizu, M; Akutsu, Y; Shimbo, A; Mori, M. Tacrolimus as an alternative treatment for patients with juvenile idiopathic arthritis MODERN RHEUMATOLOGY. 2022.07; 32 (4): 783-791. ( PubMed, DOI )

  16. Yamazaki Susumu, Shimizu Masaki, Akutsu Yuko, Shimbo Asami, Mori Masaaki. 若年性特発性関節炎患者に対する代替療法としてのタクロリムス(Tarcolimus as an alternative treatment for patients with juvenile idiopathic arthritis) Modern Rheumatology. 2022.07; 32 (4): 783-791. ( ichushi )

  17. Okano, T; Nishimura, A; Inoue, K; Naruto, T; Tokoro, S; Tomoda, T; Kamiya, T; Simbo, A; Akutsu, Y; Okamoto, K; Yeh, T; Isoda, T; Yanagimachi, M; Kajiwara, M; Imai, K; Kanegane, H; Mori, M; Morio, T; Takagi, M. Somatic mutation in <i>RUNX1</i> underlies mucocutaneus inflammatory manifestations RHEUMATOLOGY. 2021.12; 60 (12): E429-E431. ( PubMed, DOI )

  18. Asami Shimbo, Yuko Akutsu, Susumu Yamazaki, Masaki Shimizu, Masaaki Mori. Giant Iliopsoas Bursitis in Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2021.07; 73 (7): 1328. ( PubMed, DOI )

  19. Yamazaki, S; Akutsu, Y; Shimbo, A; Shimizu, M; Segawa, Y; Mori, M. Childhood-onset systemic lupus erythematosus with trisomy X and the increased risk for bone complications: a case report PEDIATRIC RHEUMATOLOGY. 2021.02; 19 (1): 20. ( PubMed, DOI )

  20. Refractory secondary thrombotic microangiopathy with kidney injury associated with systemic lupus erythematosus in a pediatric patient 2020.11; ( PubMed )

  21. Kaneda Tomoya, Tanaka Eriko, Akutsu Yuko, Kanamori Toru, Mouri Mariko, Morio Tomohiro, Mori Masaaki. 全身性エリテマトーデス患児における腎障害を伴う続発性の難治性血栓性微小血管障害症(Refractory secondary thrombotic microangiopathy with kidney injury associated with systemic lupus erythematosus in a pediatric patient) CEN Case Reports. 2020.11; 9 (4): 301-307. ( ichushi )

  22. Yamazaki, S; Shimbo, A; Akutsu, Y; Takase, H; Morio, T; Mori, M. Importance of pediatric rheumatologists and transitional care for juvenile idiopathic arthritis-associated uveitis: a retrospective series of 9 cases PEDIATRIC RHEUMATOLOGY. 2020.03; 18 (1): 26. ( PubMed, DOI )

  23. A patient with peripheral demyelinating neuropathy, central dysmyelinating leukodystrophy, Waardenburg syndrome, and severe hypoganglionosis associated with a novel SOX10 mutation 2018.05; ( PubMed )

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Conference Activities & Talks 【 display / non-display 】

  1. Masaki Shimizu, Maho Hatano, Shuya Kaneko, Futaba Miyaoka, Asami Shimbo, Hitoshi Irabu, Yuko Akutsu, Yuko Hayashi, Masaaki Mori. Distinct Roles of Serum Free and Total Interleukin 18 Level As s Biomarker For Still’s Disease and Macrophage Activation Syndrome. the 32nd Paediatric Rheumatology European Society Congress (PReS 2025 Congress) 2025.09.19 Helsinki, Finland

  2. M. Hatano, S. Kaneko, F. Miyaoka, A. Shimbo, H. Irabu, Y. Akutsu, Y. Hayashi, M. Shimizu, M. Mori. VARIATIONS OF LYMPHOCYTE SUBPOPULATIONS IN MACROPHAGE ACTIVATION SYNDROME ASSOCIATED STILL’S DISEASE: POSSIBLE ROLE OF B CELLS, NK CELLS, AND CD38+HLA-DR+CD8+ T CELLS AS A BIOMARKER FOR THE DIAGNOSIS OF MACROPHAGE ACTIVATION SYNDROME. the 32nd Paediatric Rheumatology European Society Congress (PReS 2025 Congress) 2025.09.18 Helsinki, Finland

  3. Shuya Kaneko, Asami Shimbo, Maho Hatano, Hitoshi Irabu, Yuko Akutsu, Yuko Hayashi, Shuhei Fujita, Keiji Akamine, Kenji Furuno, Junya Fujimura, Naomi Iwata, Koji Yokoyama, Masaaki Mori, Masatoshi Takagi, Masaki Shimizu. Distinct Cytokine Profiles in Kawasaki Disease and MIS-C: Identification of Biomarkers and Predictors of Coronary Artery Lesion Development. The 27th Asia-Pacific League of Associations for Rheumatology Congress (APLAR2025) 2025.09.03 福岡

  4. Shimbo A, Akutsu Y, Yamazaki S, Shimizu M, Mori M. Giant Iliopsoas Bursitis in Systemic Juvenile Idiopathic Arthritis.. Arthritis & rheumatology (Hoboken, N.J.) 2021.07.01

  5. Kaneda T, Tanaka E, Akutsu Y, Kanamori T, Mouri M, Morio T, Mori M. Refractory secondary thrombotic microangiopathy with kidney injury associated with systemic lupus erythematosus in a pediatric patient.. CEN case reports 2020.11.01

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Performance of duties 【 display / non-display 】

  • ，2025.02

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