論文・総説 - 松島　隆英

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  1. Lin Liu, Tomoki Chiba, Takahide Matsushima, Maiko Inotsume, Tomomi Kato, Yuichi Hiraoka, Hiroshi Asahara. Gene dosage-dependent roles of Mkx in postnatal tendon development and maintenance revealed by conditional deletion. Dev Biol. 2025.10; 526 15-25. ( PubMed, DOI )

  2. Takahide Matsushima, Yuki Naito, Tomoki Chiba, Ryota Kurimoto, Keiko Itano, Koji Ochiai Koichi Takahashi, Naoki Goshima, Hiroshi Asahara. Localizatome: a database for stress-dependent subcellular localization changes in proteins Database. 2025.04; 2025 baaf028. ( PubMed, DOI )

  3. Atsushi Goto, Shingo Komura, Koki Kato, Rie Maki, Akihiro Hirakawa, Hitomi Aoki, Hiroyuki Tomita, Jumpei Taguchi, Manabu Ozawa, Takahide Matsushima, Akio Kishida, Tsuyoshi Kimura, Hiroshi Asahara, Yuuki Imai, Yasuhiro Yamada, Haruhiko Akiyama. PI3K-Akt signalling regulates Scx-lineage tenocytes and Tppp3-lineage paratenon sheath cells in neonatal tendon regeneration. Nat Commun. 2025.04; 16 (1): 3734. ( PubMed, DOI )

  4. Suzu Chida, Tomoki Chiba, Yutaro Uchida, Takahide Matsushima, Ryota Kurimoto, Takayuki Miyazaki, Lisa Yagasaki, Satoshi Nakamura, Emiko Mihara, Junichi Takagi, Keiji Moriyama, Hiroshi Asahara. Impact of mechanotransduction on gene expression changes in periodontal ligament during orthodontic tooth movement. J Bone Miner Metab. 2025.02; 43 (3): 216-229. ( PubMed, DOI )

  5. Yutaro Uchida, Ryota Kurimoto, Tomoki Chiba, Takahide Matsushima, Goshi Oda, Iichiroh Onishi, Yasuto Takeuchi, Noriko Gotoh, Hiroshi Asahara. RNA binding protein ZCCHC24 promotes tumorigenicity in triple-negative breast cancer. EMBO Rep. 2024.12; 25 (12): 5352-5382. ( PubMed, DOI )

  6. Hiroki Tsutsumi, Tomoki Chiba, Yuta Fujii, Takahide Matsushima, Tsuyoshi Kimura, Akinori Kanai, Akio Kishida, Yutaka Suzuki, Hiroshi Asahara. Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells. bioRxiv. 2024.10; ( PubMed, DOI )

  7. Takahide Matsushima, Asahara Hiroshi. "Molecular mechanisms of mechanosensing and plasticity of tendons and ligaments". J Biochem. 2024.10; 176 (4): 263-269. ( PubMed, DOI )

  8. Matsushima Takahide, Asahara Hiroshi. 【生理的および病理学的臓器リモデリングと可塑性】腱・靱帯の機械受容性と可塑性の分子機構(【Physiological and Pathological Organ Remodeling and Plasticity】Molecular mechanisms of mechanosensing and plasticity of tendons and ligaments) The Journal of Biochemistry. 2024.10; 176 (4): 263-269. ( 医中誌 )

  9. Kimura, T; Maeda, H; Hagiwara, M; Hashimoto, Y; Nakamura, N; Nomura, W; Tanabe, T; Kobayashi, M; Yamamoto, M; Matsushima, T; Asahara, H; Kishida, A. Evaluation of Proinflammatory Response to Polymeric Materials Using a Macrophage Cell Line Genetically Tagged with a Luminescent Peptide ADVANCED BIOMEDICAL ENGINEERING. 2024; 13 43-51. ( DOI )

  10. Kimura Tsuyoshi, Maeda Hanako, Hagiwara Moeko, Hashimoto Yoshihide, Nakamura Naoko, Nomura Wataru, Tanabe Tadao, Kobayashi Mako, Yamamoto Masaya, Matsushima Takahide, Asahara Hiroshi, Kishida Akio. 遺伝的に発光性ペプチドで標識したマクロファージ細胞株を用いた重合体物質に対する炎症誘導反応の評価法(Evaluation of Proinflammatory Response to Polymeric Materials Using a Macrophage Cell Line Genetically Tagged with a Luminescent Peptide) Advanced Biomedical Engineering. 2024; 13 43-50. ( 医中誌 )

  11. Maiko Inotsume, Tomoki Chiba, Takahide Matsushima, Ryota Kurimoto, Mitsuyo Nakajima, Tomomi Kato, Kana Shishido, Lin Liu, Koichi Kawakami, Hiroshi Asahara. One-step generation of mice with gene editing by Tol2 transposon-dependent gRNA delivery. FEBS Lett. 2023.03; 597 (7): 975-984. ( PubMed, DOI )

  12. Hiroto Yamamoto, Yutaro Uchida, Ryota Kurimoto, Tomoki Chiba, Takahide Matsushima, Yoshiaki Ito, Maiko Inotsume, Kohei Miyata, Kenta Watanabe, Masaki Inada, Naoki Goshima, Tokujiro Uchida, Hiroshi Asahara. RNA-binding protein LIN28A upregulates transcription factor HIF1α by posttranscriptional regulation via direct binding to UGAU motifs. J Biol Chem. 2023.01; 299 (1): 102791. ( PubMed, DOI )

  13. Hiroki Tsutsumi, Ryota Kurimoto, Ryo Nakamichi, Tomoki Chiba, Takahide Matsushima, Yuta Fujii, Risa Sanada, Tomomi Kato, Kana Shishido, Yuriko Sakamaki, Tsuyoshi Kimura, Akio Kishida, Hiroshi Asahara. Generation of a tendon-like tissue from human iPS cells. J Tissue Eng. 2022.01; 13 20417314221074018. ( PubMed, DOI )

  14. Miyazaki Takayuki, Kurimoto Ryota, Chiba Tomoki, Matsushima Takahide, Nakamichi Ryo, Tsutsumi Hiroki, Takada Kaho, Yagasaki Lisa, Kato Tomomi, Shishido Kana, Kobayashi Yukiho, Matsumoto Tsutomu, Moriyama Keiji, Asahara Hiroshi. Mkxは破骨細胞の誘導を介して歯科矯正による歯の移動を制御する(Mkx regulates the orthodontic tooth movement via osteoclast induction) Journal of Bone and Mineral Metabolism. 2021.09; 39 (5): 780-786. ( 医中誌 )

  15. Yoshiaki Ito, Tokio Matsuzaki, Fumiaki Ayabe, Sho Mokuda, Ryota Kurimoto, Takahide Matsushima, Yusuke Tabata, Maiko Inotsume, Hiroki Tsutsumi, Lin Liu, Masahiro Shinohara, Yoko Tanaka, Ryo Nakamichi, Keiichiro Nishida, Martin K Lotz, Hiroshi Asahara. Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis. Nat Commun. 2021.07; 12 (1): 4148. ( PubMed, DOI )

  16. Takayuki Miyazaki, Ryota Kurimoto, Tomoki Chiba, Takahide Matsushima, Ryo Nakamichi, Hiroki Tsutsumi, Kaho Takada, Lisa Yagasaki, Tomomi Kato, Kana Shishido, Yukiho Kobayashi, Tsutomu Matsumoto, Keiji Moriyama, Hiroshi Asahara. Mkx regulates the orthodontic tooth movement via osteoclast induction. J Bone Miner Metab. 2021.05; 39 (5): 780-786. ( PubMed, DOI )

  17. Yutaro Uchida, Takahide Matsushima, Ryota Kurimoto, Tomoki Chiba, Yuki Inutani, Hiroshi Asahara. Identification of chemical compounds regulating PD-L1 by introducing HiBiT-tagged cells. FEBS Lett. 2021.03; 595 (5): 563-576. ( PubMed, DOI )

  18. Chiba T, Kurimoto R, Matsushima T, Ito Y, Nakamichi R, Lotz M, Asahara H. MicroRNA Expression Profiling, Target Identification, and Validation in Chondrocytes. Methods in molecular biology (Clifton, N.J.). 2021; 2245 151-166. ( PubMed, DOI )

  19. Keiko Itano,KojiOchiai, Takahide Matsushima,Hiroshi Asahara and Koichi Takahashi. Automation of Foci-Cell-State Judgement with Regression Models Transactions of the Institute of Systems, Control and Information Engineers. 2021; 34 (3): 69-80. ( DOI )

  20. Kurimoto R, Chiba T, Ito Y, Matsushima T, Yano Y, Miyata K, Yashiro Y, Suzuki T, Tomita K, Asahara H. The tRNA pseudouridine synthase TruB1 regulates the maturation of let-7 miRNA. The EMBO journal. 2020.10; 39 (20): e104708. ( PubMed, DOI )

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