論文・総説 - 藤井　俊光

1. Makoto Naganuma, Hisashi Shiga, Masayuki Shimoda, Minoru Matsuura, Kento Takenaka, Toshimitsu Fujii, Shojiro Yamamoto, Mao Matsubayashi, Taku Kobayashi, Nobuo Aoyama, Daisuke Saito, Kaoru Yokoyama, Kei Moriya, Kiichiro Tsuchiya, Shunsuke Shibui, Ami Kawamoto, Hiromichi Shimizu, Ryuichi Okamoto, Kazuki Sakamoto, Katsuki Yaguchi, Reiko Kunisaki, Shintaro Akiyama, Ryohei Hayashi, Keisuke Hasui, Shuji Kanmura, Shigeki Bamba, Yoshiyuki Mishima, Kazuki Kakimoto, Shinya Sugimoto, Atsushi Nakazawa, Takayuki Abe, Haruhiko Ogata, Tadakazu Hisamatsu, . First-line biologics as a treatment for ulcerative colitis: a multicenter randomized control study. J Gastroenterol. 2025.04; 60 (4): 430-441. ( PubMed, DOI )

2. Makoto Okabe, Shuji Yamamoto, Masahiro Shiokawa, Tadakazu Hisamatsu, Hajime Yamazaki, Risa Nakanishi, Kensuke Hamada, Hiroki Kitamoto, Takeshi Kuwada, Norimitsu Uza, Aki Sakatani, Toshimitsu Fujii, Masashi Ohno, Minoru Matsuura, Tomoyoshi Shibuya, Naoki Ohmiya, Makoto Ooi, Namiko Hoshi, Kei Moriya, Kiichiro Tsuchiya, Yoshiharu Yamaguchi, Reiko Kunisaki, Masahiro Takahara, Tomohisa Takagi, Tetsuo Takehara, Fumihito Hirai, Kazuki Kakimoto, Motohiro Esaki, Hiroshi Nakase, Fukunori Kinjo, Takehiro Torisu, Shuji Kanmura, Kazuyuki Narimatsu, Katsuyoshi Matsuoka, Hiroto Hiraga, Kaoru Yokoyama, Yusuke Honzawa, Makoto Naganuma, Masayuki Saruta, Yuzo Kodama, Tsutomu Chiba, Hiroshi Seno. Anti-integrin αvβ6 antibody as a biomarker for diagnosing ulcerative colitis: a nationwide multicenter validation study. J Gastroenterol. 2025.01; 60 (1): 86-95. ( PubMed, DOI )

3. Shintaro Akiyama, Hiromichi Shimizu, Akiko Tamura, Kaoru Yokoyama, Toshiyuki Sakurai, Mariko Kobayashi, Makoto Eizuka, Shunichi Yanai, Kei Nomura, Tomoyoshi Shibuya, Masahiro Takahara, Sakiko Hiraoka, Minako Sako, Atsushi Yoshida, Kozo Tsuruta, Shinichiro Yoshioka, Miki Koroku, Teppei Omori, Masayuki Saruta, Takayuki Matsumoto, Ryuichi Okamoto, Kiichiro Tsuchiya, Toshimitsu Fujii. Comparative Efficacy and Safety of Three Janus Kinase Inhibitors in Ulcerative Colitis: A Real-World Multicentre Study in Japan. Aliment Pharmacol Ther. 2024.11; Online ahead of print ( PubMed, DOI )

4. Taku Kobayashi, Kei Moriya, Toshimitsu Fujii, Shigeki Bamba, Shinichiro Shinzaki, Akihiro Yamada, Takashi Hisabe, Shintaro Sagami, Shuji Hibiya, Takahiro Amano, Noritaka Takatsu, Katsutoshi Inagaki, Ken-Ichi Iwayama, Toshifumi Hibi. Early resolution of bowel urgency by budesonide foam enema results in improved quality of life in patients with ulcerative colitis: a multicenter prospective observational study. Intest Res. 2024.07; Online ahead of print ( PubMed, DOI )

5. Hiromichi Shimizu, Yuko Aonuma, Shuji Hibiya, Ami Kawamoto, Kento Takenaka, Toshimitsu Fujii, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Ryuichi Okamoto. Long-term efficacy and safety of tofacitinib in patients with ulcerative colitis: 3-year results from a real-world study. Intest Res. 2024.07; 22 (3): 369-377. ( PubMed, DOI )

6. Motoki Makuuchi, Yoichi Kakuta, Junji Umeno, Toshimitsu Fujii, Tetsuya Takagawa, Takashi Ibuka, Miki Miura, Yu Sasaki, Sakuma Takahashi, Hiroshi Nakase, Hiroki Kiyohara, Keiichi Tominaga, Yosuke Shimodaira, Sakiko Hiraoka, Nobuhiro Ueno, Shunichi Yanai, Takeo Yoshihara, Kazuki Kakimoto, Katsuyoshi Matsuoka, Ryohei Hayashi, Sohachi Nanjo, Itaru Iwama, Yoh Ishiguro, Hirofumi Chiba, Katsuya Endo, Takashi Kagaya, Tomohiro Fukuda, Yasuhisa Sakata, Takahiro Kudo, Tomohisa Takagi, Kenichi Takahashi, Makoto Naganuma, Masaru Shinozaki, Noriyuki Ogata, Hiroki Tanaka, Kazuyuki Narimatsu, Haruka Miyazaki, Takashi Ishige, Motoyuki Onodera, Yu Hashimoto, Hiroshi Nagai, Yusuke Shimoyama, Takeo Naito, Rintaro Moroi, Hisashi Shiga, , Yoshitaka Kinouchi, Akira Andoh, Tadakazu Hisamatsu, Atsushi Masamune. Real-world NUDT15 genotyping and thiopurine treatment optimization in inflammatory bowel disease: a multicenter study. J Gastroenterol. 2024.06; 59 (6): 468-482. ( PubMed, DOI )

7. Shintaro Akiyama, Kaoru Yokoyama, Soichi Yagi, Shinichiro Shinzaki, Kozo Tsuruta, Shinichiro Yoshioka, Minako Sako, Hiromichi Shimizu, Mariko Kobayashi, Toshiyuki Sakurai, Kei Nomura, Tomoyoshi Shibuya, Masahiro Takahara, Sakiko Hiraoka, Kyohei Sugai, Shunichi Yanai, Atsushi Yoshida, Miki Koroku, Teppei Omori, Masayuki Saruta, Takayuki Matsumoto, Ryuichi Okamoto, Kiichiro Tsuchiya, Toshimitsu Fujii. Efficacy and safety of filgotinib for ulcerative colitis: A real-world multicenter retrospective study in Japan. Aliment Pharmacol Ther. 2024.03; Online ahead of print ( PubMed, DOI )

8. Marc Ferrante, Peter M Irving, Maria T Abreu, Jeffrey Axler, Xiang Gao, Qian Cao, Toshimitsu Fujii, Astrid Rausch, Joana Torres, Ezequiel Neimark, Alexandra Song, Kori Wallace, Kristina Kligys, Sofie Berg, Xiaomei Liao, Qing Zhou, Jasmina Kalabic, Brian Feagan, Remo Panaccione. Maintenance Risankizumab Sustains Induction Response in Patients with Crohn's Disease in a Randomized Phase 3 Trial. J Crohns Colitis. 2024.03; 18 (3): 416-423. ( PubMed, DOI )

9. Xiang Gao, Toshimitsu Fujii, Byong Duk Ye, Jen-Wei Chou, Ken Sugimoto, Qian Cao, Kristina Kligys, Kaoru Murakoshi, Dennis Teng, Yafei Zhang, Hiroshi Nakase. Efficacy and safety of risankizumab for Crohn's disease in patients from Asian countries: a post hoc subanalysis of the global phase 3 ADVANCE, MOTIVATE, and FORTIFY studies. J Gastroenterol Hepatol. 2024.01; 39 (1): 55-65. ( PubMed, DOI )

10. Laurent Peyrin-Biroulet, Jessica R Allegretti, David T Rubin, Brian Bressler, Matthew Germinaro, Kuan-Hsiang Gary Huang, Nicole Shipitofsky, Hongyan Zhang, Rebbecca Wilson, Chenglong Han, Brian G Feagan, William J Sandborn, Julian Panés, Tadakazu Hisamatsu, Gary R Lichtenstein, Bruce E Sands, Axel Dignass ; QUASAR Study Group. Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: QUASAR Phase 2b Induction Study. Gastroenterology. 2023.12; 165 (6): 1443-1457. ( PubMed, DOI )

11. Ami Kawamoto, Kento Takenaka, Shuji Hibiya, Yoshio Kitazume, Hiromichi Shimizu, Toshimitsu Fujii, Eiko Saito, Kazuo Ohtsuka, Ryuichi Okamoto. Combination of leucine-rich alpha-2 glycoprotein and fecal markers detect Crohn's disease activity confirmed by balloon-assisted enteroscopy. Intest Res. 2023.11; Online ahead of print ( PubMed, DOI )

12. Shuji Hibiya, Takashi Fujii, Toshimitsu Fujii, Shinji Suzuki, Mayumi Kondo, Shinya Ooka, Yohei Furumoto, Seishin Azuma, Kei Tanaka, Hitoshi Kurata, Shohei Tanaka, Masayuki Kurosaki, Kazuyoshi Nagayama, Fumihiko Kusano, Yasuhiro Iizuka, Takahiro Kawamura, Hidekazu Ikemiyagi, Shinya Sakita, Tsunehito Yauchi, Hideki Watanabe, Ami Kawamoto, Yusuke Matsuyama, Kazuo Ohtsuka, Ryuichi Okamoto. COVID-19 severity is associated with the risk of gastrointestinal bleeding. BMJ Open Gastroenterol. 2023.11; 10 (1): ( PubMed, DOI )

13. Takayuki Yamamoto, Hiroshi Nakase, Kenji Watanabe, Shinichiro Shinzaki, Noritaka Takatsu, Toshimitsu Fujii, Ryuichi Okamoto, Katsuyoshi Matsuoka, Akihiro Yamada, Reiko Kunisaki, Minoru Matsuura, Hisashi Shiga, Shigeki Bamba, Yohei Mikami, Takahiro Shimoyama, Satoshi Motoya, Takehiro Torisu, Taku Kobayashi, Naoki Ohmiya, Masayuki Saruta, Koichiro Matsuda, Takayuki Matsumoto, Atsuo Maemoto, Yoko Murata, Shinichi Yoshigoe, Shinya Nagasaka, Tsutomu Yajima, Tadakazu Hisamatsu. Diagnosis and Clinical Features of Perianal Lesions in Newly Diagnosed Crohn's Disease: Subgroup Analysis from Inception Cohort Registry Study of Patients with Crohn's Disease (iCREST-CD). J Crohns Colitis. 2023.08; 17 (8): 1193-1206. ( PubMed, DOI )

14. Katsuyoshi Matsuoka, Hajime Yamazaki, Masakazu Nagahori, Taku Kobayashi, Teppei Omori, Yohei Mikami, Toshimitsu Fujii, Shinichiro Shinzaki, Masayuki Saruta, Minoru Matsuura, Takayuki Yamamoto, Satoshi Motoya, Toshifumi Hibi, Mamoru Watanabe, Jovelle Fernandez, Shunichi Fukuhara, Tadakazu Hisamatsu. Association of ulcerative colitis symptom severity and proctocolectomy with multidimensional patient-reported outcomes: a cross-sectional study. J Gastroenterol. 2023.08; 58 (8): 751-765. ( PubMed, DOI )

15. Yoshio Kitazume, Kento Takenaka, Kazuo Ohtsuka, Yasuo Ozawa, Koichiro Kimura, Ryosuke Watanabe, Junichi Tsuchiya, Toshimitsu Fujii, Masakazu Nagahori, Mamoru Watanabe, Ukihide Tateishi. Motility Mapping Quantification Using the Classical Optical Flow Algorithm for Small Bowel Crohn's Disease: Comparison with Balloon-assisted Enteroscopy Findings. Magn Reson Med Sci. 2023.07; 22 (3): 325-334. ( PubMed, DOI )

16. Kento Takenaka, Ami Kawamoto, Yoshio Kitazume, Toshimitsu Fujii, Yumi Udagawa, Hiromichi Shimizu, Shuji Hibiya, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto. Transmural Remission Characterized by High Biologic Concentrations Demonstrates Better Prognosis in Crohn's Disease. J Crohns Colitis. 2023.06; 17 (6): 855-862. ( PubMed, DOI )

17. Kento Takenaka, Yoshio Kitazume, Ami Kawamoto, Toshimitsu Fujii, Yumi Udagawa, Ryosuke Wanatabe, Hiromichi Shimizu, Shuji Hibiya, Masakazu Nagahori, Kazuo Ohtsuka, Hiroyuki Sato, Akihiro Hirakawa, Mamoru Watanabe, Ryuichi Okamoto. Serum Leucine-Rich α2 Glycoprotein: A Novel Biomarker for Transmural Inflammation in Crohn's Disease. Am J Gastroenterol. 2023.06; 118 (6): 1028-1035. ( PubMed, DOI )

18. Fujiwara S, Kawamoto A, Motobayashi M, Hibiya S, Takenaka K, Shimizu H, Saito E, Fujii T, Nagahori M, Kawata D, Umezawa N, Hosoya T, Yasuda S, Ohtsuka K, Okamoto R. Hemorrhagic gastric ulcer in a patient with Behcet's disease successfully treated with infliximab. DEN open. 2023.04; 3 (1): e196. ( PubMed, DOI )

19. Eiko Saito, Kazuo Ohtsuka, Ami Kawamoto, Toshimitsu Fujii, Kento Takenaka, Shuji Hibiya, Hiromichi Shimizu, Masakazu Nagahori, Shohei Tomii, Ryuichi Okamoto. A case of venous stasis colitis possibly caused by eplerenone. Clin J Gastroenterol. 2023.02; 16 (1): 69-72. ( PubMed, DOI )

20. Katsuyoshi Matsuoka, Toshimitsu Fujii, Ryuichi Okamoto, Akihiro Yamada, Reiko Kunisaki, Minoru Matsuura, Kenji Watanabe, Hisashi Shiga, Noritaka Takatsu, Shigeki Bamba, Yohei Mikami, Takayuki Yamamoto, Takahiro Shimoyama, Satoshi Motoya, Takehiro Torisu, Taku Kobayashi, Naoki Ohmiya, Masayuki Saruta, Koichiro Matsuda, Takayuki Matsumoto, Hiroshi Nakase, Atsuo Maemoto, Shinichiro Shinzaki, Yoko Murata, Shinichi Yoshigoe, Ayako Sasaki, Tsutomu Yajima, Tadakazu Hisamatsu. Characteristics of adult patients newly diagnosed with Crohn's disease: interim analysis of the nation-wide inception cohort registry study of patients with Crohn's disease in Japan (iCREST-CD). J Gastroenterol. 2022.11; 57 (11): 867-878. ( PubMed, DOI )

21. Ami Kawamoto, Toshimitsu Fujii, Ryuji Mitani, Yasuhiro Suzuki, Tsunehito Yauchi, Ryuichi Okamoto. Serum Levels of Infliximab Biosimilar in a Child Delivered From a Mother Treated for Ulcerative Colitis.( Online ahead of print.) Inflamm Bowel Dis. 2022.06; ( PubMed, DOI )

22. Shuji Hibiya, Kazuo Ohtsuka, Kento Takenaka, Ami Kawamoto, Yusuke Matsuyama, Yumi Udagawa, Maiko Motobayashi, Hiromichi Shimizu, Toshimitsu Fujii, Eiko Saito, Masakazu Nagahori, Ryuichi Okamoto, Mamoru Watanabe. Mucosal healing of small intestinal stricture is associated with improved prognosis post-dilation in Crohn's disease. BMC Gastroenterol. 2022.05; 22 (1): 218. ( PubMed, DOI )

23. Kaoru Suzuki, Yoichi Kakuta, Takeo Naito, Tetsuya Takagawa, Hiroyuki Hanai, Hiroshi Araki, Yu Sasaki, Hirotake Sakuraba, Makoto Sasaki, Tadakazu Hisamatsu, Satoshi Motoya, Takayuki Matsumoto, Motoyuki Onodera, Yoh Ishiguro, Hiroshi Nakase, Akira Andoh, Sakiko Hiraoka, Masaru Shinozaki, Toshimitsu Fujii, Takehiko Katsurada, Taku Kobayashi, Mikihiro Fujiya, Takafumi Otsuka, Naoki Oshima, Yasuo Suzuki, Yuichirou Sato, Ryota Hokari, Mitsunori Noguchi, Yuki Ohta, Minoru Matsuura, Yosuke Kawai, Katsushi Tokunaga, Masao Nagasaki, Hisaaki Kudo, Naoko Minegishi, Daisuke Okamoto, Yusuke Shimoyama, Rintaro Moroi, Masatake Kuroha, Hisashi Shiga, Dalin Li, Dermot P B McGovern, Yoshitaka Kinouchi, Atsushi Masamune, . Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2022.01; 28 (1): 21-31. ( PubMed, DOI )

24. Hiromichi Shimizu, Toshimitsu Fujii, Kenji Kinoshita, Ami Kawamoto, Shuji Hibiya, Kento Takenaka, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto. Intravenous tacrolimus is a superior induction therapy for acute severe ulcerative colitis compared to oral tacrolimus. BMC Gastroenterol. 2021.12; 21 (1): 494. ( PubMed, DOI )

25. Takeo Yoshihara, Shinichiro Shinzaki, Takahiro Amano, Hideki Iijima, Tetsuo Takehara, Nagamu Inoue, Motoi Uchino, Motohiro Esaki, Taku Kobayashi, Masayuki Saruta, Ken Sugimoto, Shiro Nakamura, Keisuke Hata, Fumihito Hirai, Sakiko Hiraoka, Toshimitsu Fujii, Minoru Matsuura, Katsuyoshi Matsuoka, Kenji Watanabe, Hiroshi Nakase, Mamoru Watanabe. Concomitant use of an immunomodulator with ustekinumab as an induction therapy for Crohn's disease: A systematic review and meta-analysis. J Gastroenterol Hepatol. 2021.07; 36 (7): 1744-1753. ( PubMed, DOI )

26. Hiroshi Nakase, Motoi Uchino, Shinichiro Shinzaki, Minoru Matsuura, Katsuyoshi Matsuoka, Taku Kobayashi, Masayuki Saruta, Fumihito Hirai, Keisuke Hata, Sakiko Hiraoka, Motohiro Esaki, Ken Sugimoto, Toshimitsu Fuji, Kenji Watanabe, Shiro Nakamura, Nagamu Inoue, Toshiyuki Itoh, Makoto Naganuma, Tadakazu Hisamatsu, Mamoru Watanabe, Hiroto Miwa, Nobuyuki Enomoto, Tooru Shimosegawa, Kazuhiko Koike. Evidence-based clinical practice guidelines for inflammatory bowel disease 2020. J Gastroenterol. 2021.06; 56 (6): 489-526. ( PubMed, DOI )

27. Yoshio Kitazume, Kento Takenaka, Kazuo Ohtsuka, Koichiro Kimura, Yusuke Ogihara, Tomoyuki Fujioka, Junichi Tsuchiya, Toshimitsu Fujii, Mamoru Watanabe, Ukihide Tateisi. Crohn disease: magnetic resonance enterocolonography features of endoscopic ulcer stages reclassified with the healing process and the relationships to prognoses. Jpn J Radiol. 2021.05; 39 (5): 459-476. ( PubMed, DOI )

28. Motoi Uchino, Hiroki Ikeuchi, Keisuke Hata, Tomohiro Minagawa, Yuki Horio, Ryuichi Kuwahara, Shiro Nakamura, Kenji Watanabe, Masayuki Saruta, Toshimitsu Fujii, Taku Kobayashi, Ken Sugimoto, Fumihito Hirai, Motohiro Esaki, Sakiko Hiraoka, Katsuyoshi Matsuoka, Shinichiro Shinzaki, Minoru Matsuura, Nagamu Inoue, Hiroshi Nakase, Mamoru Watanabe. Does anti-tumor necrosis factor alpha prevent the recurrence of Crohn's disease? Systematic review and meta-analysis. J Gastroenterol Hepatol. 2021.04; 36 864-872. ( PubMed, DOI )

29. Motoi Uchino, Hiroki Ikeuchi, Keisuke Hata, Tomohiro Minagawa, Yuki Horio, Ryuichi Kuwahara, Shiro Nakamura, Kenji Watanabe, Masayuki Saruta, Toshimitsu Fujii, Taku Kobayashi, Ken Sugimoto, Fumihito Hirai, Motohiro Esaki, Sakiko Hiraoka, Katsuyoshi Matsuoka, Shinichiro Shinzaki, Minoru Matsuura, Nagamu Inoue, Hiroshi Nakase, Mamoru Watanabe. Intestinal cancer in patients with Crohn's disease: A systematic review and meta-analysis. J Gastroenterol Hepatol. 2021.02; 36 329-336. ( PubMed, DOI )

30. Chikako Watanabe, Masakazu Nagahori, Toshimitsu Fujii, Kaoru Yokoyama, Naoki Yoshimura, Taku Kobayashi, Hirokazu Yamagami, Kazuya Kitamura, Kagaya Takashi, Shiro Nakamura, Makoto Naganuma, Shunji Ishihara, Motohiro Esaki, Maria Yonezawa, Reiko Kunisaki, Atsushi Sakuraba, Naoaki Kuji, Soichiro Miura, Toshifumi Hibi, Yasuo Suzuki, Ryota Hokari. Non-adherence to medications in pregnant ulcerative colitis patients contributes to disease flares and adverse pregnancy outcomes. Dig Dis Sci. 2021.02; 66 577-586. ( PubMed, DOI )

31. Shuji Hibiya, Yusuke Matsuyama, Toshimitsu Fujii, Chiaki Maeyashiki, Eiko Saito, Kimiko Ito, Hiromichi Shimizu, Ami Kawamoto, Maiko Motobayashi, Kento Takenaka, Masakazu Nagahori, Masayuki Kurosaki, Tsunehito Yauchi, Kazuo Ohtsuka, Takeo Fujiwara, Ryuichi Okamoto, Mamoru Watanabe. 5-aminosalicylate-intolerant patients are at increased risk of colectomy for ulcerative colitis. Aliment Pharmacol Ther. 2021.01; 53 (1): 103-113. ( PubMed, DOI )

32. Yoshio Kitazume, Junichi Tsuchiya, Kento Takenaka, Kazuo Ohtsuka, Koichiro Kimura, Ryosuke Watanabe, Tomoyuki Fujioka, Toshimitsu Fujii, Mamoru Watanabe, Ukihide Tateisi. High b-value computed diffusion-weighted imaging for differentiating bowel inflammation in Crohn's disease. Eur J Radiol. 2020.10; 133 109362. ( PubMed, DOI )

33. Shigeki Bamba, Ryosuke Sakemi, Toshimitsu Fujii, Teruyuki Takeda, Shin Fujioka, Kento Takenaka, Hiroki Kitamoto, Shotaro Umezawa, Hirotake Sakuraba, Toshihiro Inokuchi, Norimasa Fukata, Shinta Mizuno, Masaki Yamashita, Shinichiro Shinzaki, Hiroki Tanaka, Hidetoshi Takedatsu, Ryo Ozaki, Kei Moriya, Manabu Ishii, Tetsu Kinjo, Keiji Ozeki, Makoto Ooi, Ryohei Hayashi, Kazuki Kakimoto, Yuichi Shimodate, Kazuya Kitamura, Akihiro Yamada, Akira Sonoda, Yu Nishida, Kyouko Yoshioka, Shinya Ashizuka, Fumiaki Takahashi, Toshio Shimokawa, Taku Kobayashi, Akira Andoh, Toshifumi Hibi. A nationwide, multi-center, retrospective study of symptomatic small bowel stricture in patients with Crohn's disease. J. Gastroenterol. 2020.06; 55 (6): 615-626. ( PubMed, DOI )

34. Hiromichi Shimizu, Toshimitsu Fujii, Shuji Hibiya, Maiko Motobayashi, Kohei Suzuki, Kento Takenaka, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe. Rapid prediction of 1-year efficacy of tofacitinib for treating refractory ulcerative colitis. Intest Res. 2020.06; Online ahead of print.. ( PubMed, DOI )

35. Kento Takenaka, Toshimitsu Fujii, Kohei Suzuki, Hiromichi Shimizu, Maiko Motobayashi, Shuji Hibiya, Eiko Saito, Masakazu Nagahori, Mamoru Watanabe, Kazuo Ohtsuka. Small Bowel Healing Detected by Endoscopy in Patients With Crohn's Disease After Treatment With Antibodies Against Tumor Necrosis Factor. Clin. Gastroenterol. Hepatol.. 2019.08; ( PubMed, DOI )

36. Shintaro Akiyama, Katsuyoshi Matsuoka, Kyoko Fukuda, Shunsuke Hamada, Mikiko Shimizu, Kosaku Nanki, Shinta Mizuno, Hiroki Kiyohara, Mari Arai, Shinya Sugimoto, Yasushi Iwao, Haruhiko Ogata, Tadakazu Hisamatsu, Makoto Naganuma, Maiko Motobayashi, Kohei Suzuki, Kento Takenaka, Toshimitsu Fujii, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Mayumi Mochizuki, Mamoru Watanabe, Masayuki Hashiguchi, Takanori Kanai. Long-term effect of NUDT15 R139C on hematologic indices in inflammatory bowel disease patients treated with thiopurine. J. Gastroenterol. Hepatol.. 2019.05; ( PubMed, DOI )

37. Atsushi Yoshida, Noriko Kamata, Akihiro Yamada, Yoko Yokoyama, Teppei Omori, Toshimitsu Fujii, Ryohei Hayashi, Tetsu Kinjo, Akira Matsui, Norimasa Fukata, Sakuma Takahashi, Ryosuke Sakemi, Noriyuki Ogata, Shinya Ashizuka, Shigeki Bamba, Makoto Ooi, Shuji Kanmura, Katsuya Endo, Takuya Yoshino, Hiroki Tanaka, Toshio Morizane, Shinichiro Shinzaki, Taku Kobayashi. Pneumonia in patients with inflammatory bowel disease. Inflamm Intest Dis. 2019.04; 3 (4): 167-172. ( PubMed, DOI )

38. Shinichiro Shinzaki, Toshimitsu Fujii, Shigeki Bamba, Maiko Ogawa, Taku Kobayashi, Masahide Oshita, Hiroki Tanaka, Keiji Ozeki, Sakuma Takahashi, Hiroki Kitamoto, Kazuhito Kani, Sohachi Nanjo, Takeshi Sugaya, Yuko Sakakibara, Toshihiro Inokuchi, Kazuki Kakimoto, Akihiro Yamada, Hisae Yasuhara, Yoko Yokoyama, Takuya Yoshino, Akira Matsui, Misaki Nakamura, Taku Tomizawa, Ryosuke Sakemi, Noriko Kamata, Toshifumi Hibi. Seven days triple therapy for eradication of Helicobacter pylori does not alter the disease activity of patients with inflammatory bowel disease. Intest Res. 2018.10; 16 (4): 609-618. ( PubMed, DOI )

39. Fumihiko Iwamoto, Katsuyoshi Matsuoka, Maiko Motobayashi, Kento Takenaka, Toru Kuno, Keisuke Tanaka, Yuya Tsukui, Shoji Kobayashi, Takashi Yoshida, Toshimitsu Fujii, Eiko Saito, Tatsuya Yamaguchi, Masakazu Nagahori, Tadashi Sato, Kazuo Ohtsuka, Nobuyuki Enomoto, Mamoru Watanabe. Prediction of disease activity of Crohn's disease through fecal calprotectin evaluated by balloon-assisted endoscopy. J. Gastroenterol. Hepatol.. 2018.06; ( PubMed, DOI )

40. Kento Takenaka, Kazuo Ohtsuka, Yoshio Kitazume, Katsuyoshi Matsuoka, Masakazu Nagahori, Toshimitsu Fujii, Eiko Saito, Maiko Kimura, Tomoyuki Fujioka, Mamoru Watanabe. Utility of Magnetic Resonance Enterography For Small Bowel Endoscopic Healing in Patients With Crohn's Disease. Am. J. Gastroenterol.. 2018.02; 113 (2): 283-294. ( PubMed, DOI )

41. Taku Kobayashi, Asahi Hishida, Hiroki Tanaka, Yoichiro Nuki, Shigeki Bamba, Akihiro Yamada, Toshimitsu Fujii, Shinichiro Shinzaki, Yoko Yokoyama, Atsushi Yoshida, Keiji Ozeki, Shinya Ashizuka, Noriko Kamata, Sohachi Nanjo, Kazuki Kakimoto, Misaki Nakamura, Akira Matsui, Ryosuke Yamauchi, Sakuma Takahashi, Taku Tomizawa, Takuya Yoshino, Toshifumi Hibi. Real-world Experience of Anti-tumor Necrosis Factor Therapy for Internal Fistulas in Crohn's Disease: A Retrospective Multicenter Cohort Study. Inflamm. Bowel Dis.. 2017.12; 23 (12): 2245-2251. ( PubMed, DOI )

42. Kento Takenaka, Kazuo Ohtsuka, Yoshio Kitazume, Katsuyoshi Matsuoka, Toshimitsu Fujii, Masakazu Nagahori, Maiko Kimura, Tomoyuki Fujioka, Akihiro Araki, Mamoru Watanabe. Magnetic resonance evaluation for small bowel strictures in Crohn's disease: comparison with balloon enteroscopy. [Epub ahead of print] J. Gastroenterol.. 2017.08; 52 (8): 879-888. ( PubMed, DOI )

43. Kazuo Ohtsuka, Kento Takenaka, Yoshio Kitazume, Toshimitsu Fujii, Katsuyoshi Matsuoka, Maiko Kimura, Takashi Nagaishi, Mamoru Watanabe. Magnetic resonance enterography for the evaluation of the deep small intestine in Crohn's disease. Intest Res. 2016.04; 14 (2): 120-126. ( PubMed, DOI )

44. Kento Takenaka, Kazuo Ohtsuka, Yoshio Kitazume, Masakazu Nagahori, Toshimitsu Fujii, Eiko Saito, Tomoyuki Fujioka, Katsuyoshi Matsuoka, Makoto Naganuma, Mamoru Watanabe. Correlation of the Endoscopic and Magnetic Resonance Scoring Systems in the Deep Small Intestine in Crohn's Disease. Inflamm. Bowel Dis.. 2015.05; ( PubMed, DOI )

45. Eiko Saito, Masakazu Nagahori, Toshimitsu Fujii, Kazuo Ohtsuka, Mamoru Watanabe. Efficacy of salvage therapy and its effect on operative outcomes in patients with ulcerative colitis. Digestion. 2014.01; 89 (1): 55-60. ( PubMed, DOI )

46. Toshimitsu Fujii, Makoto Naganuma, Yoshio Kitazume, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe. Advancing magnetic resonance imaging in Crohn's disease. Digestion. 2014.01; 89 (1): 24-30. ( PubMed, DOI )

47. Masakazu Nagahori, Toshimitsu Fujii, Eiko Saito, Kazuo Ohtsuka, Mamoru Watanabe. Biologics treatment for ulcerative colitis. Nihon Shokakibyo Gakkai Zasshi. 2013.11; 110 (11): 1909-1915. ( PubMed )

48. Makoto Naganuma, Toshimitsu Fujii, Reiko Kunisaki, Naoki Yoshimura, Masakazu Takazoe, Yoshiaki Takeuchi, Eiko Saito, Masakazu Nagahori, Keiko Asakura, Toru Takebayashi, Mamoru Watanabe. Incidence and characteristics of the 2009 influenza (H1N1) infections in inflammatory bowel disease patients. J Crohns Colitis. 2013.05; 7 (4): 308-313. ( PubMed, DOI )

49. Makoto Naganuma, Masakazu Nagahori, Toshimitsu Fujii, Junko Morio, Eiko Saito, Mamoru Watanabe. Poor recall of prior exposure to varicella zoster, rubella, measles, or mumps in patients with IBD. Inflamm. Bowel Dis.. 2013.02; 19 (2): 418-422. ( PubMed, DOI )

50. 藤井 俊光, 岡本 隆一. 【炎症性腸疾患に対する検査法の進歩】Cross-sectional imagingとしてのMRIとtransmural healing 日本消化器病学会雑誌. 2023.11; 120 (11): 888-897. ( PubMed, DOI )

51. 竹中 健人, 藤井 俊光, 大塚 和朗, 岡本 隆一. 【小腸画像診断のトピックス】MR enterography 胃と腸. 2023.11; 58 (11): 1491-1498. ( DOI )

52. 藤井 俊光, 日比谷 秀爾, 岡本 隆一, 渡辺 守. 【炎症性腸疾患update-診断・治療の最新知見-】炎症性腸疾患の治療　薬物治療　5-ASA製剤 日本臨床. 2022.03; 80 (3): 433-438. ( 医中誌 )

53. 斎藤 恵子, 太田 一樹, 長堀 正和, 藤井 俊光, 竹中 健人, 大塚 和朗, 井津井 康浩, 篠原 夏美, 松下 由佳子, 岡本 隆一. 外来クローン病患者における生体インピーダンス法を用いた体組成の評価 学会誌JSPEN. 2022.02; 4 (1): 35-43. ( 医中誌 )

54. 大塚 和朗, 竹中 健人, 齊藤 詠子, 日比谷 秀爾, 河本 亜美, 森川 亮, 藤井 俊光, 清水 寛路, 長堀 正和, 岡本 隆一 . 【炎症性腸疾患の粘膜治癒を再考する】Crohn病における小腸粘膜治癒評価の意義　バルーン内視鏡の立場から 胃と腸. 2022.02; 57 (2): 173-181. ( 医中誌 )

55. 河本亜美、藤井俊光. 炎症性腸疾患の分子標的治療を総括する〜抗TNF-α抗体製剤〜 INTESTINE. 2021.09; 25 (3): 259-266.

56. 藤井 俊光, 岡本 隆一. 【同種・同効薬の使い分け　疾患×基本薬のエビデンスを整理する】(第4章)消化器系の基本薬の使い分け　潰瘍性大腸炎への分子標的薬はどう選ぶ? 薬事. 2021.05; 63 (7): 1387-1394. ( 医中誌 )

57. 日比谷 秀爾, 藤井 俊光, 岡本 隆一. 【炎症性腸疾患診療の新たな展開】鑑別すべき腸疾患 臨牀と研究. 2021.05; 98 (5): 569-572. ( 医中誌 )

58. 日比谷秀爾、藤井俊光、岡本隆一、渡辺守. 潰瘍性大腸炎における5-ASA不耐は予後不良である INTESTINE. 2021.05; 25 (1): 115-118.

59. 竹中健人、北詰良雄、大塚和朗、藤井俊光、渡辺　守、岡本隆一. MR enterographyの実際と有用性 臨床消化器内科. 2021.01; 36 (2): 208-214.

60. 大島　茂、藤井俊光、渡辺　守. 炎症性腸疾患とサイトカインを標的とした生物学的製剤 炎症と免疫. 2020.10; 28 (6): 66-71.

61. 藤井俊光、長堀正和、渡辺　守. 潰瘍性大腸炎、クローン病 臨床と研究. 2020.04; 97 (4): 32-38.

62. 藤井俊光. 抗TNFα抗体 消化器外科. 2020.03; 43 (3): 333-336.

63. 大塚和朗、竹中健人、藤井俊光、齊藤詠子、本林麻衣子、清水寛路、日比谷秀爾、長堀正和、土屋輝一郎、渡辺　守. 重症度評価と粘膜治癒の意義 消化器内視鏡. 2020.02; 32 (2): 256-261.

64. 竹中健人、大塚和朗、鈴木康平、藤井俊光、渡辺守. クローン病におけるCross-Sectional Imaging IBD research. 2019.03; 13 (1): 32-37.

65. 大塚和朗、福田将義、竹中健人、鈴木康平、長堀正和、藤井俊光、齊藤詠子、小林正典、渡辺　守. 【大腸内視鏡の話題-機器と挿入法】 挿入補助具　バルーン内視鏡　a.シングルバルーン Intestine. 2018.11; 22 (6): 567-569. ( 医中誌 )

66. 藤井俊光、北詰良雄、竹中健人、渡辺 守. 【炎症性腸疾患(第2版)-病因解明と診断・治療の最新知見-】 炎症性腸疾患の検査・診断　炎症性腸疾患の画像診断　CT・MRI診断　MRI 日本臨床. 2018.04; 76 (3): 231-237.

67. 藤井俊光. 【特集:IBD治療薬の最適化とは?】IBD治療におけるカルシニューリン阻害薬の最適化 IBD Research. 2018.03; 12 (1): 32-36.

68. 藤井俊光、渡辺 守. 【病態から考え出されたIBD治療の進歩】 序説 Intestine. 2018.03; 22 (3): 221-224.

69. 藤井俊光, 渡辺　守. 【クローン病の最新薬物療法】 クローン病のステロイド治療　プレドニゾロン、ブデソニドの使い方 消化器の臨床. 2018.02; 21 (1): 19-26. ( 医中誌 )

70. 藤井俊光. 【コモンな難病　炎症性腸疾患の薬物療法】 IBD治療薬の選び方、使い方　新規治療法 薬事. 2018.01; 60 (1): 58-65. ( 医中誌 )

71. 藤井俊光、渡辺　守. 【潰瘍性大腸炎-診断治療のアップデート】 潰瘍性大腸炎の病因・疫学 消化器・肝臓内科. 2018.01; 3 (1): 1-7. ( 医中誌 )

72. 大塚和朗, 荒木昭博, 竹中健人, 藤井俊光, 渡辺　守. 【消化器内視鏡の基礎知識と基本テクニック】 小腸　小腸検査法の適応と使い分け 消化器内視鏡. 2017.03; 29 (3): 478-480. ( 医中誌 )

73. 藤井俊光、渡辺　守. 【炎症性腸疾患-最近の診断・治療-】 炎症性腸疾患の定義・疫学 日本臨床. 2017.03; 75 (3): 357-363. ( 医中誌 )

74. 北詰良雄, 竹中健人, 藤井俊光, 中江康太, 浜中隆宏, 大塚和朗, 渡辺　守, 立石宇貴秀. クローン病に対するMR enterocolonography　実践のポイント 映像情報Medical. 2016.12; 48 (14): 77-82. ( 医中誌 )

75. 大塚和朗, 藤井俊光, 竹中健人, 松岡克善, 長堀正和, 木村麻衣子, 冨井翔平, 渡辺　守. 【診断に迷うIBDの非典型例】 非典型像を呈したクローン病 Intestine. 2016.11; 20 (6): 559-564. ( 医中誌 )

76. 藤井俊光、渡辺　守. 【炎症性腸疾患を解き明かす-今後の解決すべき問題に向けて-】炎症性腸疾患モニタリング・画像診断の変遷　新たな低侵襲検査への挑戦　MRI検査の有用性 The GI Forefront. 2016.09; 12 (1): 35-37. ( 医中誌 )

77. 北詰 良雄, 竹中 健人, 大塚 和朗, 藤井 俊光, 松岡 克善, 木村 麻衣子, 長堀 正和, 立石 宇貴秀. 【非腫瘍性消化管疾患の画像診断-beyond barium study and endoscopy-】 MR enterography 画像診断. 2016.08; 36 (10): 1028-1037. ( 医中誌 )

78. 大塚和朗、竹中健人、北詰良雄、藤井俊光、松岡克善、長堀正和、木村麻衣子、岩本史光、齊藤詠子、渡辺　守. 【新しい小腸・大腸画像診断-現状と将来展望】 MR entero-colonographyの有用性 胃と腸. 2016.06; 51 (7): 899-908. ( 医中誌 )

79. 藤井俊光. 【臨床各科 差分解説：内科　消化器】クローン病におけるMRIの役割 日本医事新報. 2016.04; (4081): 54.

80. 藤井俊光、渡辺　守. IBD治療のピットフォール(第9回)　IBD患者の深部静脈血栓症/肺塞栓症のリスクと診断 IBD Research. 2016.03; 10 (1): 52-57. ( 医中誌 )

81. 藤井俊光、渡辺　守. 【クローン病治療の最前線】 Mucosal healingの評価方法 Intestine. 2016.03; 20 (2): 181-189. ( 医中誌 )

82. 大塚 和朗、竹中健人、長堀正和、松岡克善、藤井俊光、齊藤詠子、渡辺　守. 【特集　下部消化管：炎症からの発癌】炎症発癌の診断（４）小腸のサーベイランス INTESTINE. 2015.08; 19 (4): 381-384.

83. 藤井俊光、渡辺　守. クローン病画像モダリティとしてのMRI 日本消化器病学会雑誌. 2015.07; 112 (7): 15-22.

84. 藤井 俊光, 渡辺 守. 【クローン病診療における画像診断・内視鏡診断の活用法】 クローン病画像モダリティーとしてのMRI 日本消化器病学会雑誌. 2015.07; 112 (7): 1251-1258. ( 医中誌 )

85. 大塚和朗、竹中健人、松沢　優、 前田康晴、小形典之、林　靖子、土屋 輝一郎、和田祥城、福田将義、長堀正和、齊藤詠子、藤井俊光、松岡克善、工藤進英、渡辺　守. 【診断困難な炎症性腸疾患】 潰瘍性大腸炎・Crohn病の副病変 胃と腸. 2015.06; 50 (7): 907-915. ( 医中誌 )

86. 竹中健人,大塚和朗,北詰良雄,藤井俊光,渡辺　守. クローン病の小腸病変に対するMR所見とバルーン内視鏡所見の比較 INTESRINE. 2015.05; 19 (3): 312-314.

87. 藤井 俊光. MRIによる腸管評価法 Medical Science Digest. 2015.05; 41 (5): 199-200. ( 医中誌 )

88. 藤井俊光. 【New Technology】MRIによる腸管評価法 （MRI for inflammatory bowel disease） Medical Science Digest. 2015.04; 41 (5): 5-6.

89. 竹中健人, 大塚和朗, 北詰良雄, 藤井俊光, 齊藤詠子, 長堀正和, 松岡克善, 藤岡友之, 渡辺　守. 診断講座　症例から学ぶIBD鑑別診断のコツ　新規モダリティによる画像診断のポイントシリーズ(その1)　MREを用いたIBDの診断のポイント IBD Research. 2015.03; 9 (1): 66-73. ( 医中誌 )

90. 藤井俊光, 渡辺 守. 巻頭3. 炎症性腸疾患ム生物学的製剤の課題と展望 消化器疾患　最新の治療　2015-2016. 2015.02;

91. 長堀正和、藤井俊光、齊藤詠子、大塚和朗、渡辺　守. 【潰瘍性大腸炎診療のトピックス】 潰瘍性大腸炎に対する生物学的製剤による治療 日本消化器病学会雑誌. 2013.11; 110 (11): 1909-1915. ( 医中誌 )

92. 大塚和朗、藤井俊光、齊藤詠子、長堀正和、渡辺　守. 【Colitic cancerにどう立ち向かうか】 Dysplasiaをどう取り扱うか 消化器の臨床. 2013.06; 16 (3): 271-275. ( 医中誌 )

93. 藤井 俊光, 北詰 良雄, 長沼 誠, 齊藤 詠子, 長堀 正和, 大塚 和朗、渡辺 守. 【小腸疾患の臨床-最近の進歩】 クローン病に対するMREC(MR enterocolonography)の有用性 臨床消化器内科. 2013.05; 28 (7): 1069-1075. ( 医中誌 )

94. 藤井 俊光, 長沼 誠, 森尾 純子, 齊藤 詠子, 長堀 正和, 渡辺 守. 【炎症性腸疾患の薬物療法の極意】 免疫調節薬/分子生物製剤を用いた難治性潰瘍性大腸炎に対する治療戦略 消化器内科. 2012.01; 54 (1): 28-33. ( 医中誌 )