Personnel Information

写真a

SAITOU Tetsuya


Job title

Junior Associate Professor
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Campus Career 【 display / non-display 】

  • 2012.12
    -
    2018.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Environmental Response， Rheumatology， Assistant Professor
  • 2018.04
    -
    2022.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Environmental Response， Rheumatology， Assistant Professor
  • 2022.04
    -
    2024.09
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Environmental Response， Rheumatology， Junior Associate Professor
  • 2024.10
    -
    Now
    Institute of Science Tokyo， -， Graduate Schools， Bio-Environmental Response， Department of Rheumatology， Junior Associate Professor
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Published Papers & Misc 【 display / non-display 】

  1. Sato M, Saito T, Komiya Y, Noda S, Tagawa Y, Yamamoto A, Iwai H, Endo K, Koga H, Takahara Y, Sugimoto K, Sekiya I, Kawakami E, Hosoya T, Yasuda S. Reciprocal Regulation of GLI1 and GLI3 Fine Tunes the Pathogenic Behavior of Synovial Fibroblasts in Rheumatoid Arthritis. International journal of rheumatic diseases. 2026.06; 29 (6): e70690. ( PubMed, DOI )

  2. Kise M, Shimamura M, Umezawa N, Tanaka N, Da R, Li S, Hosoya T, Saito T, Terao C, Yasuda S. The exacerbating role of Ras guanyl-releasing protein 1 in idiopathic inflammatory myopathies. Clinical immunology (Orlando, Fla.). 2026.01; 282 110636. ( PubMed, DOI )

  3. Itakura T, Sasaki H, Hosoya T, Umezawa N, Saito T, Iwai H, Hasegawa H, Sato H, Hirakawa A, Imai K, Morio T, Kimura N, Yasuda S. The role of TRECs/KRECs as immune indicators that reflect immunophenotypes and predict the risk of infection in systemic autoimmune diseases. Immunological medicine. 2025.09; 48 (3): 233-244. ( PubMed, DOI )

  4. Hosoya, T; Saito, T; Yasuda, S. Cyclin dependent kinase inhibitor: a long-awaited, late-coming, novel class agent in rheumatoid arthritis RHEUMATOLOGY. 2024.11; 64 (3): 916-918. ( PubMed, DOI )

  5. Tagawa, Y; Saito, T; Iwai, H; Sato, M; Noda, S; Yamamoto, A; Ota, M; Endo, K; Koga, H; Takahara, Y; Sugimoto, K; Sekiya, I; Fujio, K; Kawakami, E; Mizoguchi, F; Yasuda, S. ARID5B is a negative modulator of IL-6 production in rheumatoid arthritis synovial fibroblasts IMMUNOLOGICAL MEDICINE. 2024.07; 47 (3): 176-185. ( PubMed, DOI )

  6. Mikami, R; Saito, T; Mizuno, R; Kabasawa, Y; Matsuo, K. Gingival Necrosis Associated with Septic Shock of Unknown Origin in Patient with Systemic Lupus Erythematosus: A Case Report BULLETIN OF TOKYO DENTAL COLLEGE. 2024; 65 (4): 83-90. ( PubMed, DOI )

  7. Sako, Y; Sato-Kaneko, F; Shukla, NM; Yao, SY; Belsuzarri, MM; Chan, MC; Saito, T; Lao, FS; Kong, H; Puffer, M; Messer, K; Pu, MY; Cottam, HB; Carson, DA; Hayashi, T. Identification of a Novel Small Molecule That Enhances the Release of Extracellular Vesicles with Immunostimulatory Potency via Induction of Calcium Influx ACS CHEMICAL BIOLOGY. 2023.04; 18 (4): 982-993. ( PubMed, DOI )

  8. Sugisawa, K; Takase, H; Sugihara, T; Saito, T; Iwasaki, Y; Kamoi, K; Kawaguchi, T; Yasuda, S; Ohno-Matsui, K. Granulomatosis with Polyangiitis Complicated by Severe Exudative Retinal Detachment and Orbital Granuloma Successfully Controlled with Rituximab: A Case Report CASE REPORTS IN OPHTHALMOLOGY. 2023; 14 (1): 214-222. ( PubMed, DOI )

  9. Noda, S; Hosoya, T; Komiya, Y; Tagawa, Y; Endo, K; Komori, K; Koga, H; Takahara, Y; Sugimoto, K; Sekiya, I; Saito, T; Mizoguchi, F; Yasuda, S. CD34<SUP>+</SUP>THY1<SUP>+</SUP> synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro (vol 24, 45, 2022) ARTHRITIS RESEARCH & THERAPY. 2022.09; 24 (1): 224. ( PubMed, DOI )

  10. Hosoya, T; Saito, T; Baba, H; Tanaka, N; Noda, S; Komiya, Y; Tagawa, Y; Yamamoto, A; Mizoguchi, F; Kawahata, K; Miyasaka, N; Kohsaka, H; Yasuda, S. Chondroprotective effects of CDK4/6 inhibition via enhanced ubiquitin-dependent degradation of JUN in synovial fibroblasts RHEUMATOLOGY. 2022.08; 61 (8): 3427-3438. ( PubMed, DOI )

  11. Yamamoto A, Saito T, Hosoya T, Kawahata K, Asano Y, Sato S, Mizoguchi F, Yasuda S, Kohsaka H. Therapeutic Effect of Cyclin-Dependent Kinase 4/6 Inhibitor on Dermal Fibrosis in Murine Models of Systemic Sclerosis. Arthritis & rheumatology (Hoboken, N.J.). 2022.05; 74 (5): 860-870. ( PubMed, DOI )

  12. Shukla, NM; Sato-Kaneko, F; Yao, SY; Pu, MY; Chan, M; Lao, FS; Sako, Y; Saito, T; Messer, K; Hayashi, T; Cottam, HB; Corr, M; Carson, DA. A Triple High Throughput Screening for Extracellular Vesicle Inducing Agents With Immunostimulatory Activity FRONTIERS IN PHARMACOLOGY. 2022.04; 13 869649. ( PubMed, DOI )

  13. Noda, S; Hosoya, T; Komiya, Y; Tagawa, Y; Endo, K; Komori, K; Koga, H; Takahara, Y; Sugimoto, K; Sekiya, I; Saito, T; Mizoguchi, F; Yasuda, S. CD34<SUP>+</SUP>THY1<SUP>+</SUP> synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro ARTHRITIS RESEARCH & THERAPY. 2022.02; 24 (1): 45. ( PubMed, DOI )

  14. Saito, T; Shukla, NM; Sato-Kaneko, F; Sako, Y; Hosoya, T; Yao, SY; Lao, FS; Messer, K; Pu, MY; Chan, M; Chu, PJ; Cottam, HB; Hayashi, T; Carson, DA; Corr, M. Small Molecule Calcium Channel Activator Potentiates Adjuvant Activity ACS CHEMICAL BIOLOGY. 2022.01; 17 (1): 217-229. ( PubMed, DOI )

  15. Saito, T; Sako, Y; Sato-Kaneko, F; Hosoya, T; Yao, SY; Lao, FS; Shpigelman, J; Messer, K; Pu, MY; Shukla, NM; Chan, M; Chu, PJ; Cottam, HB; Hayashi, T; Carson, DA; Corr, M. Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge FRONTIERS IN IMMUNOLOGY. 2021.09; 12 701445. ( PubMed, DOI )

  16. Shpigelman, J; Lao, FS; Yao, SY; Li, CY; Saito, T; Sato-Kaneko, F; Nolan, JP; Shukla, NM; Pu, MY; Messer, K; Cottam, HB; Carson, DA; Corr, M; Hayashi, T. Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release FRONTIERS IN PHARMACOLOGY. 2021.04; 12 668609. ( PubMed, DOI )

  17. Matsuo, Y; Saito, T; Yamamoto, A; Kohsaka, H. Origins of fibroblasts in rheumatoid synovial tissues: Implications from organ fibrotic models MODERN RHEUMATOLOGY. 2018; 28 (4): 579-582. ( PubMed, DOI )

  18. Komiya, Y; Saito, T; Mizoguchi, F; Kohsaka, H. Hemophagocytic Syndrome Complicated with Dermatomyositis Controlled Successfully with Infliximab and Conventional Therapies INTERNAL MEDICINE. 2017; 56 (23): 3237-3241. ( PubMed, DOI )

  19. Y Tagawa, T Saito, K Takada, K Kawahata, H Kohsaka. Successful treatment of severe refractory lupus hepatitis with mycophenolate mofetil. Lupus. 2016.04; 25 (5): 543-546. ( PubMed, DOI )

  20. Yusuke Matsuo, Fumitaka Mizoguchi, Tetsuya Saito, Kimito Kawahata, Satoshi Ueha, Kouji Matsushima, Yutaka Inagaki, Nobuyuki Miyasaka, Hitoshi Kohsaka. Local fibroblast proliferation but not influx is responsible for synovial hyperplasia in a murine model of rheumatoid arthritis. Biochem. Biophys. Res. Commun.. 2016.02; 470 (3): 504-509. ( PubMed, DOI )

  21. Takumi Matsumoto, Tetsuya Saito, Hitoshi Kohsaka. A case of chronic myelomonocytic leukemia complicated with spondyloarthritis. Mod Rheumatol. 2015.10; 28 (2): 1-3. ( PubMed, DOI )

  22. Fumitaka Mizoguchi, Yousuke Murakami, Tetsuya Saito, Nobuyuki Miyasaka, Hitoshi Kohsaka. miR-31 controls osteoclast formation and bone resorption by targeting RhoA. Arthritis Res. Ther.. 2013.11; 15 (5): R102. ( PubMed, DOI )

  23. Yousuke Murakami, Fumitaka Mizoguchi, Tetsuya Saito, Nobuyuki Miyasaka, Hitoshi Kohsaka. p16(INK4a) exerts an anti-inflammatory effect through accelerated IRAK1 degradation in macrophages. J. Immunol.. 2012.11; 189 (10): 5066-5072. ( PubMed, DOI )

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