Jamie A Dean, Shyam K Tanguturi, Daniel Cagney, Kee-Young Shin, Gilbert Youssef, Ayal Aizer, Rifaquat Rahman, Lubna Hammoudeh, David Reardon, Eudocia Lee, Jorg Dietrich, Kaoru Tamura, Masaru Aoyagi, Lacey Wickersham, Patrick Y Wen, Paul Catalano, Daphne Haas-Kogan, Brian M Alexander, Franziska Michor. Phase I study of a novel glioblastoma radiation therapy schedule exploiting cell-state plasticity. Neuro Oncol. 2022.11; 25 (6): 1100-1112. ( PubMed, DOI )

Takami Hirokazu, Elzawahry Asmaa, Mamatjan Yasin, Fukushima Shintaro, Fukuoka Kohei, Suzuki Tomonari, Yanagisawa Takaaki, Matsushita Yuko, Nakamura Taishi, Satomi Kaishi, Tanaka Shota, Mukasa Akitake, Saito Nobuhito, Kanamori Masayuki, Kumabe Toshihiro, Tominaga Teiji, Kobayashi Keiichi, Nagane Motoo, Iuchi Toshihiko, Tamura Kaoru, Maehara Taketoshi, Sugiyama Kazuhiko, Yoshimoto Koji, Sakai Keiichi, Nonaka Masahiro, Asai Akio, Yokogami Kiyotaka, Takeshima Hideo, Narita Yoshitaka, Shibui Soichiro, Nakazato Yoichi, Hama Natsuko, Totoki Yasushi, Kato Mamoru, Shibata Tatsuhiro, Nishikawa Ryo, Matsutani Masao, Ichimura Koichi. Transcriptome and methylome analysis of CNS germ cell tumor finds its cell-of-origin in embryogenesis and reveals shared similarities with testicular counterparts NEURO-ONCOLOGY. 2022.08; 24 (8): 1246-1258. ( PubMed, DOI )

Satomi Kaishi, Takami Hirokazu, Fukushima Shintaro, Yamashita Satoshi, Matsushita Yuko, Nakazato Yoichi, Suzuki Tomonari, Tanaka Shota, Mukasa Akitake, Saito Nobuhito, Kanamori Masayuki, Kumabe Toshihiro, Tominaga Teiji, Kobayashi Keiichi, Nagane Motoo, Iuchi Toshihiko, Yoshimoto Koji, Tamura Kaoru, Maehara Taketoshi, Sakai Keiichi, Sugiyama Kazuhiko, Yokogami Kiyotaka, Takeshima Hideo, Nonaka Masahiro, Asai Akio, Ushijima Toshikazu, Matsutani Masao, Nishikawa Ryo, Ichimura Koichi. 12p gain is predominantly observed in non-germinomatous germ cell tumors and identifies an unfavorable subgroup of central nervous system germ cell tumors NEURO-ONCOLOGY. 2022.05; 24 (5): 834-846. ( PubMed, DOI )

Yokoyama Kota, Oyama Jun, Tsuchiya Junichi, Karakama Jun, Tamura Kaoru, Inaji Motoki, Tanaka Yoji, Kobayashi Daisuke, Maehara Taketoshi, Tateishi Ukihide. Branch-like enhancement on contrast enhanced MRI is a specific finding of cerebellar lymphoma compared with other pathologies SCIENTIFIC REPORTS. 2022.03; 12 (1): 3591. ( PubMed, DOI )

Shimizu Kazuhide, Tamura Kaoru, Hara Shoko, Inaji Motoki, Tanaka Yoji, Kobayashi Daisuke, Sugawara Takashi, Wakimoto Hiroaki, Nariai Tadashi, Ishii Kenji, Sakuma Ichiro, Maehara Taketoshi. Correlation of Intraoperative 5-ALA-Induced Fluorescence Intensity and Preoperative C-11-Methionine PET Uptake in Glioma Surgery CANCERS. 2022.03; 14 (6): ( PubMed, DOI )

Mariko Noda, Motoki Inaji, Jun Karakama, Yukika Arai, Masae Kuroha, Kaoru Tamura, Yoji Tanaka, Taketoshi Maehara. Ischemic Stroke with Multiple Cerebral Artery Stenosis in a Patient with an Anaplastic Astrocytoma during Bevacizumab Treatment: A Case Report. NMC Case Rep J. 2022; 9 13-17. ( PubMed, DOI )

Fujimoto Kenji, Arita Hideyuki, Satomi Kaishi, Yamasaki Kai, Matsushita Yuko, Nakamura Taishi, Miyakita Yasuji, Umehara Toru, Kobayashi Keiichi, Tamura Kaoru, Tanaka Shota, Higuchi Fumi, Okita Yoshiko, Kanemura Yonehiro, Fukai Junya, Sakamoto Daisuke, Uda Takehiro, Machida Ryunosuke, Kuchiba Aya, Maehara Taketoshi, Nagane Motoo, Nishikawa Ryo, Suzuki Hiroyoshi, Shibuya Makoto, Komori Takashi, Narita Yoshitaka, Ichimura Koichi. TERT promoter mutation status is necessary and sufficient to diagnose IDH-wildtype diffuse astrocytic glioma with molecular features of glioblastoma ACTA NEUROPATHOLOGICA. 2021.08; 142 (2): 323-338. ( PubMed, DOI )

Takahashi Satoshi, Takahashi Masamichi, Kinoshita Manabu, Miyake Mototaka, Kawaguchi Risa, Shinojima Naoki, Mukasa Akitake, Saito Kuniaki, Nagane Motoo, Otani Ryohei, Higuchi Fumi, Tanaka Shota, Hata Nobuhiro, Tamura Kaoru, Tateishi Kensuke, Nishikawa Ryo, Arita Hideyuki, Nonaka Masahiro, Uda Takehiro, Fukai Junya, Okita Yoshiko, Tsuyuguchi Naohiro, Kanemura Yonehiro, Kobayashi Kazuma, Sese Jun, Ichimura Koichi, Narita Yoshitaka, Hamamoto Ryuji. Fine-Tuning Approach for Segmentation of Gliomas in Brain Magnetic Resonance Images with a Machine Learning Method to Normalize Image Differences among Facilities CANCERS. 2021.03; 13 (6): ( PubMed, DOI )

Takami H, Satomi K, Fukuoka K, Fukushima S, Matsushita Y, Yamasaki K, Nakamura T, Tanaka S, Mukasa A, Saito N, Suzuki T, Yanagisawa T, Nakamura H, Sugiyama K, Tamura K, Maehara T, Nakada M, Nonaka M, Asai A, Yokogami K, Takeshima H, Iuchi T, Kanemura Y, Kobayashi K, Nagane M, Kurozumi K, Yoshimoto K, Matsuda M, Matsumura A, Hirose Y, Tokuyama T, Kumabe T, Narita Y, Shibui S, Nakazato Y, Nishikawa R, Matsutani M, Ichimura K. Low tumor cell content predicts favorable prognosis in germinoma patients. Neuro-oncology advances. 2021.01; 3 (1): vdab110. ( PubMed, DOI )

Arita Hideyuki, Matsushita Yuko, Machida Ryunosuke, Yamasaki Kai, Hata Nobuhiro, Ohno Makoto, Yamaguchi Shigeru, Sasayama Takashi, Tanaka Shota, Higuchi Fumi, Iuchi Toshihiko, Saito Kuniaki, Kanamori Masayuki, Matsuda Ken-ichiro, Miyake Yohei, Tamura Kaoru, Tamai Sho, Nakamura Taishi, Uda Takehiro, Okita Yoshiko, Fukai Junya, Sakamoto Daisuke, Hattori Yasuhiko, Pareira Eriel Sandika, Hatae Ryusuke, Ishi Yukitomo, Miyakita Yasuji, Tanaka Kazuhiro, Takayanagi Shunsaku, Otani Ryohei, Sakaida Tsukasa, Kobayashi Keiichi, Saito Ryuta, Kurozumi Kazuhiko, Shofuda Tomoko, Nonaka Masahiro, Suzuki Hiroyoshi, Shibuya Makoto, Komori Takashi, Sasaki Hikaru, Mizoguchi Masahiro, Kishima Haruhiko, Nakada Mitsutoshi, Sonoda Yukihiko, Tominaga Teiji, Nagane Motoo, Nishikawa Ryo, Kanemura Yonehiro, Kuchiba Aya, Narita Yoshitaka, Ichimura Koichi. TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2020.12; 8 (1): 201. ( PubMed, DOI )

Takami H., Fukushima S., Aoki K., Satomi K., Narumi K., Hama N., Matsushita Y., Fukuoka K., Yamasaki K., Nakamura T., Mukasa A., Saito N., Suzuki T., Yanagisawa T., Nakamura H., Sugiyama K., Tamura K., Maehara T., Nakada M., Nonaka M., Asai A., Yokogami K., Takeshima H., Luchi T., Kanemura Y., Kobayashi K., Nagane M., Kurozumi K., Yoshimoto K., Matsuda M., Matsumura A., Hirose Y., Tokuyama T., Kumabe T., Ueki K., Narita Y., Shibui S., Totoki Y., Shibata T., Nakazato Y., Nishikawa R., Matsutani M., Ichimura K.. Intratumoural immune cell landscape in germinoma reveals multipotent lineages and exhibits prognostic significance NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. 2020.02; 46 (2): 111-124. ( PubMed, DOI )

Arita Hideyuki, Matsushita Yuko, Ohno Makoto, Miyake Yohei, Saito Kuniaki, Tanaka Shota, Nakamura Taishi, Tamura Kaoru, Higuchi Fumi, Sandika Eriel, Sabit Hemragul, Hattori Yasuhiko, Yamaguchi Shigeru, Okita Yoshiko, Sakamoto Daisuke, Fukai Junya, Uda Takehiro, Hata Nohuhiro, Shofuda Tomoko, Sasayama Takashi, Mori Kanji, Kurozumi Kazuhiko, Kanamori Masayuki, Sasaki Hikaru, Kishima Haruhiko, Kanemura Yonehiro, Nakada Mitsutoshi, Sonoda Yukihiko, Nagane Motoo, Ueki Keisuke, Nishikawa Ryo, Narita Yoshitaka, Ichimura Koichi. PROGNOSTIC ROLE OF TERT PROMOTER MUTATIONS IMPROVES THE STRATIFICATION OF IDH-MUTATED LOWER GRADE GLIOMA NEURO-ONCOLOGY. 2019.11; 21 151.

Taketoshi Maehara, Kazuko Kamiya, Takamitsu Fujimaki, Akira Matsumura, Kazuhiro Hongo, Satoshi Kuroda, Mitsunori Matsumae, Hideo Takeshima, Nobuo Sugo, Naoyuki Nakao, Nobuhito Saito, Fusao Ikawa, Noriko Tamura, Kaori Sakurada, Shoko Shimokawa, Hajime Arai, Kaoru Tamura, Kazutaka Sumita, Shoko Hara, Yoko Kato, . A Questionnaire to Assess the Challenges Faced by Women Who Quit Working as Full-Time Neurosurgeons. World Neurosurg. 2019.08; 133 331-342. ( PubMed, DOI )

Shirahata Mitsuaki, Adachi Junichi, Kobayashi Keiichi, Yamasaki Fumiyuki, Tamura Kaoru, Suzuki Tomonari, Mishima Kazuhiko, Nagane Motoo, Ichimura Koichi, Nishikawa Ryo. Stratified monotherapy approach according to MGMT methylation status in elderly patients with glioblastoma. JOURNAL OF CLINICAL ONCOLOGY. 2019.05; 37 (15):

Arita Hideyuki, Ohio Makoto, Nakamura Taishi, Tamura Kaoru, Miyake Yohei, Saito Kuniaki, Tanaka Shota, Higuchi Fumi, Kanemura Yonehiro, Ichimura Koichi. Prognostic impact of TERT promoter mutation suggests its utility as a surrogate marker for 1p/19q codeletion in IDH mutated gliomas BRAIN PATHOLOGY. 2019.02; 29 193.

Tomoyuki Nakano, Kaoru Tamura, Yoji Tanaka, Motoki Inaji, Shihori Hayashi, Daisuke Kobayashi, Tadashi Nariai, Jun Toyohara, Kenji Ishii, Taketoshi Maehara. C-Methionine Positron Emission Tomography for Monitoring of Treatment Response and Recurrence in a Glioblastoma Patient on Bevacizumab Therapy: A Case Report. Case Rep Oncol. 2018.07; 11 (2): 442-449. ( PubMed, DOI )

Deepak Bhere, Kaoru Tamura, Hiroaki Wakimoto, Sung Hugh Choi, Benjamin Purow, Jeremy Debatisse, Khalid Shah. microRNA-7 upregulates death receptor 5 and primes resistant brain tumors to caspase-mediated apoptosis. Neuro-oncology. 2018.01; 20 (2): 215-224. ( PubMed, DOI )

Sung Hugh Choi, Daniel W Stuckey, Sara Pignatta, Clemens Reinshagen, Jasneet Kaur Khalsa, Nicolaas Roozendaal, Jordi Martinez-Quintanilla, Kaoru Tamura, Erhan Keles, Khalid Shah. Tumor Resection Recruits Effector T Cells and Boosts Therapeutic Efficacy of Encapsulated Stem Cells Expressing IFNβ in Glioblastomas. Clin. Cancer Res.. 2017.11; 23 (22): 7047-7058. ( PubMed, DOI )

Xiaoshu Dong, Kaoru Tamura, Daisuke Kobayashi, Noboru Ando, Kazutaka Sumita, Taketoshi Maehara. LAPTM4B-35 is a novel prognostic factor for glioblastoma. J. Neurooncol.. 2017.04; 132 (2): 295-303. ( PubMed, DOI )

Shintaro Fukushima, Satoshi Yamashita, Hisato Kobayashi, Hirokazu Takami, Kohei Fukuoka, Taishi Nakamura, Kai Yamasaki, Yuko Matsushita, Hiromi Nakamura, Yasushi Totoki, Mamoru Kato, Tomonari Suzuki, Kazuhiko Mishima, Takaaki Yanagisawa, Akitake Mukasa, Nobuhito Saito, Masayuki Kanamori, Toshihiro Kumabe, Teiji Tominaga, Motoo Nagane, Toshihiko Iuchi, Koji Yoshimoto, Masahiro Mizoguchi, Kaoru Tamura, Keiichi Sakai, Kazuhiko Sugiyama, Mitsutoshi Nakada, Kiyotaka Yokogami, Hideo Takeshima, Yonehiro Kanemura, Masahide Matsuda, Akira Matsumura, Kazuhiko Kurozumi, Keisuke Ueki, Masahiro Nonaka, Akio Asai, Nobutaka Kawahara, Yuichi Hirose, Tatusya Takayama, Yoichi Nakazato, Yoshitaka Narita, Tatsuhiro Shibata, Masao Matsutani, Toshikazu Ushijima, Ryo Nishikawa, Koichi Ichimura, . Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas. Acta Neuropathol.. 2017.03; 133 (3): 445-462. ( PubMed, DOI )

Taishi Nakamura, Satoshi Yamashita, Kazutaka Fukumura, Jun Nakabayashi, Kazuhiro Tanaka, Kaoru Tamura, Kensuke Tateishi, Manabu Kinoshita, Shintaro Fukushima, Hirokazu Takami, Kohei Fukuoka, Kai Yamazaki, Yuko Matsushita, Makoto Ohno, Yasuji Miyakita, Soichiro Shibui, Atsuhiko Kubo, Takashi Shuto, Sylvia Kocialkowski, Shoji Yamanaka, Akitake Mukasa, Takashi Sasayama, Kazuhiko Mishima, Taketoshi Maehara, Nobutaka Kawahara, Motoo Nagane, Yoshitaka Narita, Hiroyuki Mano, Toshikazu Ushijima, Koichi Ichimura. Genome-wide DNA methylation profiling identifies primary central nervous system lymphoma as a distinct entity different from systemic diffuse large B-cell lymphoma. Acta Neuropathol.. 2017.02; 133 (2): 321-324. ( PubMed, DOI )

Takahiro Ogishima, Kaoru Tamura, Daisuke Kobayashi, Motoki Inaji, Shihori Hayashi, Reina Tamura, Tadashi Nariai, Kenji Ishii, Taketoshi Maehara. ATRX status correlates with 11 C-methionine uptake in WHO grade II and III gliomas with IDH1 mutations. Brain Tumor Pathol. 2017.01; 34 (1): 20-27. ( PubMed, DOI )

Hideyuki Arita, Kai Yamasaki, Yuko Matsushita, Taishi Nakamura, Asanao Shimokawa, Hirokazu Takami, Shota Tanaka, Akitake Mukasa, Mitsuaki Shirahata, Saki Shimizu, Kaori Suzuki, Kuniaki Saito, Keiichi Kobayashi, Fumi Higuchi, Takeo Uzuka, Ryohei Otani, Kaoru Tamura, Kazutaka Sumita, Makoto Ohno, Yasuji Miyakita, Naoki Kagawa, Naoya Hashimoto, Ryusuke Hatae, Koji Yoshimoto, Naoki Shinojima, Hideo Nakamura, Yonehiro Kanemura, Yoshiko Okita, Manabu Kinoshita, Kenichi Ishibashi, Tomoko Shofuda, Yoshinori Kodama, Kanji Mori, Yusuke Tomogane, Junya Fukai, Koji Fujita, Yuzo Terakawa, Naohiro Tsuyuguchi, Shusuke Moriuchi, Masahiro Nonaka, Hiroyoshi Suzuki, Makoto Shibuya, Taketoshi Maehara, Nobuhito Saito, Motoo Nagane, Nobutaka Kawahara, Keisuke Ueki, Toshiki Yoshimine, Etsuo Miyaoka, Ryo Nishikawa, Takashi Komori, Yoshitaka Narita, Koichi Ichimura. A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas. Acta Neuropathol Commun. 2016.08; 4 (1): 79. ( PubMed, DOI )

Koichi Ichimura, Shintaro Fukushima, Yasushi Totoki, Yuko Matsushita, Ayaka Otsuka, Arata Tomiyama, Tohru Niwa, Hirokazu Takami, Taishi Nakamura, Tomonari Suzuki, Kohei Fukuoka, Takaaki Yanagisawa, Kazuhiko Mishima, Yoichi Nakazato, Fumie Hosoda, Yoshitaka Narita, Soichiro Shibui, Akihiko Yoshida, Akitake Mukasa, Nobuhito Saito, Toshihiro Kumabe, Masayuki Kanamori, Teiji Tominaga, Keiichi Kobayashi, Saki Shimizu, Motoo Nagane, Toshihiko Iuchi, Masahiro Mizoguchi, Koji Yoshimoto, Kaoru Tamura, Taketoshi Maehara, Kazuhiko Sugiyama, Mitsutoshi Nakada, Keiichi Sakai, Yonehiro Kanemura, Masahiro Nonaka, Akio Asai, Kiyotaka Yokogami, Hideo Takeshima, Nobutaka Kawahara, Tatsuya Takayama, Masahiro Yao, Mamoru Kato, Hiromi Nakamura, Natsuko Hama, Ryuichi Sakai, Toshikazu Ushijima, Masao Matsutani, Tatsuhiro Shibata, Ryo Nishikawa, . Recurrent neomorphic mutations of MTOR in central nervous system and testicular germ cell tumors may be targeted for therapy. Acta Neuropathol.. 2016.06; 131 (6): 889-901. ( PubMed, DOI )

T Nakamura, K Tateishi, T Niwa, Y Matsushita, K Tamura, M Kinoshita, K Tanaka, S Fukushima, H Takami, H Arita, A Kubo, T Shuto, M Ohno, Y Miyakita, S Kocialkowski, T Sasayama, N Hashimoto, T Maehara, S Shibui, T Ushijima, N Kawahara, Y Narita, K Ichimura. Recurrent mutations of CD79B and MYD88 are the hallmark of primary central nervous system lymphomas. Neuropathol. Appl. Neurobiol.. 2016.04; 42 (3): 279-290. ( PubMed, DOI )

Hirokazu Takami, Shintaro Fukushima, Kohei Fukuoka, Tomonari Suzuki, Takaaki Yanagisawa, Yuko Matsushita, Taishi Nakamura, Hideyuki Arita, Akitake Mukasa, Nobuhito Saito, Masayuki Kanamori, Toshihiro Kumabe, Teiji Tominaga, Keiichi Kobayashi, Motoo Nagane, Toshihiko Iuchi, Kaoru Tamura, Taketoshi Maehara, Kazuhiko Sugiyama, Mitsutoshi Nakada, Yonehiro Kanemura, Masahiro Nonaka, Kiyotaka Yokogami, Hideo Takeshima, Yoshitaka Narita, Soichiro Shibui, Yoichi Nakazato, Ryo Nishikawa, Koichi Ichimura, Masao Matsutani. Human chorionic gonadotropin is expressed virtually in all intracranial germ cell tumors. J. Neurooncol.. 2015.08; 124 (1): 23-32. ( PubMed, DOI )

Sung Hugh Choi, Kaoru Tamura, Rajiv Kumar Khajuria, Deepak Bhere, Irina Nesterenko, Jack Lawler, Khalid Shah. Antiangiogenic variant of TSP-1 targets tumor cells in glioblastomas. Mol. Ther.. 2015.02; 23 (2): 235-243. ( PubMed, DOI )

Matthias Duebgen, Jordi Martinez-Quintanilla, Kaoru Tamura, Shawn Hingtgen, Navid Redjal, Hiroaki Wakimoto, Khalid Shah. Stem cells loaded with multimechanistic oncolytic herpes simplex virus variants for brain tumor therapy. J. Natl. Cancer Inst.. 2014.06; 106 (6): dju090. ( PubMed, DOI )

Kaoru Tamura, Masaru Aoyagi. Stem cells and the origin of different glioma subtypes. Response. J. Neurosurg.. 2014.04; 120 (4): 1010-1011. ( PubMed )

Kaoru Tamura, Masaru Aoyagi. CD133-positive stem cells. Response. J. Neurosurg.. 2014.04; 120 (4): 1012. ( PubMed )

Kaoru Tamura, Masaru Aoyagi, Noboru Ando, Takahiro Ogishima, Hiroaki Wakimoto, Masaaki Yamamoto, Kikuo Ohno. Expansion of CD133-positive glioma cells in recurrent de novo glioblastomas after radiotherapy and chemotherapy. J. Neurosurg.. 2013.11; 119 (5): 1145-1155. ( PubMed, DOI )

Masaru Aoyagi, Yoshihisa Kawano, Masashi Tamaki, Kaoru Tamura, Kikuo Ohno. Combined extradural subtemporal and anterior transpetrosal approach to tumors located in the interpeduncular fossa and the upper clivus. Acta Neurochir (Wien). 2013.08; 155 (8): 1401-1407. ( PubMed, DOI )

Kaoru Tamura, Hiroaki Wakimoto, Aayush S Agarwal, Samuel D Rabkin, Deepak Bhere, Robert L Martuza, Toshihiko Kuroda, Randa Kasmieh, Khalid Shah. Multimechanistic tumor targeted oncolytic virus overcomes resistance in brain tumors. Mol. Ther.. 2013.01; 21 (1): 68-77. ( PubMed, DOI )

Kaoru Tamura, Masaru Aoyagi, Hiroaki Wakimoto, Noboru Ando, Tadashi Nariai, Masaaki Yamamoto, Kikuo Ohno. Accumulation of CD133-positive glioma cells after high-dose irradiation by Gamma Knife surgery plus external beam radiation. J. Neurosurg.. 2010.08; 113 (2): 310-318. ( PubMed, DOI )

Arnaud Couzinet, Kaoru Tamura, Hui-Min Chen, Keishiro Nishimura, Zhichao Wang, Yasuyuki Morishita, Kazuyoshi Takeda, Hideo Yagita, Hideyuki Yanai, Tadatsugu Taniguchi, Tomohiko Tamura. A cell-type-specific requirement for IFN regulatory factor 5 (IRF5) in Fas-induced apoptosis. Proc. Natl. Acad. Sci. U.S.A.. 2008.02; 105 (7): 2556-2561. ( PubMed, DOI )

Kaoru Tamura, Masaru Aoyagi, Hiroaki Wakimoto, Masashi Tamaki, Kohei Yamamoto, Masaaki Yamamoto, Kikuo Ohno. Malignant transformation eight years after removal of a benign epidermoid cyst: a case report. J. Neurooncol.. 2006.08; 79 (1): 67-72. ( PubMed, DOI )