Personnel Information

写真a

ISHII Taku


Job title

Junior Associate Professor
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Graduating School 【 display / non-display 】

  • Tokyo Medical and Dental University, Faculty of Medicine, 2003.03, Graduated

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Graduate School 【 display / non-display 】

  • Graduate School of Medical and Dental Sciences, Global Health Promotion, Doctor's Course, 2023.03, Completed

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Degree 【 display / non-display 】

  • Doctor of Philosophy, Tokyo Medical and Dental University

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Campus Career 【 display / non-display 】

  • 2004.04
    -
    2005.03
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Pediatrics, Maternal and Woman's Medicine， Pediatrics， Trainee Resident
  • 2009.04
    -
    2010.03
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Pediatrics, Maternal and Woman's Medicine， Pediatrics， Senior Resident
  • 2011.09
    -
    2014.03
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Pediatrics, Maternal and Woman's Medicine， Pediatrics， Assistant Professor
  • 2018.04
    -
    2019.03
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Hospital Departments， Department of Pediatrics, Maternal and Woman's Medicine， Pediatrics， Assistant Professor
  • 2018.04
    -
    Now
    Institute of Science Tokyo， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Bio-Environmental Response， Department of Pediatrics and Developmental Biology， Assistant Professor
  • 2018.04
    -
    Now
    Institute of Science Tokyo， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Environmental Response， Pediatrics and Developmental Biology， Assistant Professor
  • 2018.04
    -
    Now
    Institute of Science Tokyo， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Bio-Environmental Response， Department of Pediatrics and Developmental Biology， Assistant Professor
  • 2019.04
    -
    2023.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Public Health， Department of Global Health Promotion， Graduate Student
  • 2023.04
    -
    2023.09
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Clinical Medicine， Department of Pediatrics, Perinatal, and Women's Medicine， Pediatrics， Assistant Professor
  • 2023.10
    -
    2024.09
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Endowed Departments， Department of Pediatrics, Perinatal and Maternal Medicine， Junior Associate Professor
  • 2024.10
    -
    Now
    Institute of Science Tokyo， -， Graduate Schools， Endowed Departments， Pediatrics, Perinatal and Maternal Medicine (Ibaraki)， Junior Associate Professor

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External Career 【 display / non-display 】

  • 2003.06
    -
    2004.03
    , Trainee Resident
  • 2005.04
    -
    2006.03
    , Resident
  • 2010.04
    -
    2011.08
    , Resident
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Academic Society Affiliations 【 display / non-display 】

  • Japanese Colledge of Cardiology

  • Japanese Society of Pediatric Electrocardiology

  • Japanese Societry for Adult Congenital Heart Disease

  • Japanese Society of Fetal Cardiology

  • Japanese Pulmonary Circulation and Pulmonary Hypertension Society

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Research Areas 【 display / non-display 】

  • Pediatric cardiology

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Qualification Acquired 【 display / non-display 】

  • Doctor

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Published Papers & Misc 【 display / non-display 】

  1. Kana Inoue, Taku Ishii, Yohei Yamaguchi, Satoshi Nagahara, Makito Sakurai, Susumu Hosokawa, Shozaburo Doi. Challenges in accurately assessing acute vasoreactivity in paediatric pulmonary arterial hypertension: case reports highlighting the impact of sedation on diagnostic accuracy Eur Heart J Case Rep. 2025.08; 9 (8): ytaf357. ( PubMed, DOI )

  2. Taku Ishii, Keiko Uchida, Susumu Hosokawa, Reina Ishizaki, Naofumi F Sumitomo, Yoshiyuki Furutani, Hidekazu Ishida, Shinichi Takatsuki, Kei Inai, Kunihiko Takahashi, Shigetoyo Kogaki, Hiroyuki Fukushima, Yuichi Tamura, Hiroyuki Yamagishi, Shozaburo Doi, . Pharmacological Treatment Practices for Patients with Congenital Heart Disease and Pulmonary Hypertension in Japan: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR). Am J Cardiol. 2025.08; ( PubMed, DOI )

  3. Ryuta Orimoto, Eriko Adachi, Maki Gau, Yoko Saito, Haruki Yamano, Hisae Nakatani, Shizuka Kirino, Kengo Moriyama, Yohei Yamaguchi, Tomoko Mizuno, Taku Ishii, Masayuki Yoshida, Kenichi Kashimada, Kei Takasawa. Hyaluronidase 2 deficiency due to novel compound heterozygous variants in HYAL2: a case report of siblings with HYAL2 deficiency showing different clinical severity and literature review. J Hum Genet. 2025.06; 70 (6): 321-324. ( PubMed, DOI )

  4. Sakurai M, Hosokawa S, Yamaguchi Y, Kirimura S, Ihara K, Ohashi K, Furukawa T, Sasano T, Kashimada K, Ishii T. Cyclopamine Attenuates Pulmonary Arterial Hypertension Development: Implications of Hedgehog Signaling Involvement for the Pathophysiology. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2025.05; 39 (10): e70628. ( PubMed, DOI )

  5. Nagashima-Otsuki A, Ishii T, Yamaguchi Y, Hosokawa S, Doi S. Implantable Cardioverter Defibrillator for Primary Prevention in Children With Arrhythmogenic Right Ventricular Cardiomyopathy: A Case Series. Cureus. 2025.01; 17 (1): e77253. ( PubMed, DOI )

  6. Ishii T, Nawa N, Hosokawa S, Morio T, Fujiwara T. Exploring viral infections' role in Kawasaki disease onset: A study during the COVID-19 pandemic. Journal of medical virology. 2024.05; 96 (5): e29660. ( PubMed, DOI )

  7. Yogi, A; Iemura, R; Nakatani, H; Takasawa, K; Gau, M; Yamauchi, T; Yoshida, M; Moriyama, K; Ishii, T; Hosokawa, S; Yamada, M; Suzuki, H; Kosaki, K; Kashimada, K; Morio, T. BMP2 is a potential causative gene for isolated dextrocardia situs solitus EUROPEAN JOURNAL OF MEDICAL GENETICS. 2023.09; 66 (9): 104820. ( PubMed, DOI )

  8. Ishii T, Nawa N, Doi S, Morio T, Fujiwara T. Association between the initiation of insurance coverage for fetal echocardiography and mortality from congenital heart disease in infants: An interrupted time series analysis. Paediatric and perinatal epidemiology. 2023.09; 37 (7): 607-617. ( PubMed, DOI )

  9. Yamaguchi Y, Hosokawa S, Haraguchi G, Kajikawa Y, Sakurai M, Ishii T, Ando N, Morio T, Doi S, Furukawa T. The Anti-Inflammatory Effects and Clinical Potential of Dexmedetomidine in Pulmonary Arterial Hypertension. The Journal of pharmacology and experimental therapeutics. 2023.05; 385 (2): 88-94. ( PubMed, DOI )

  10. Nakamura A, Adachi E, Matsubara Y, Ishii T, Hosokawa S, Kashimada K, Takasawa K. Monitoring hypoparathyroidism in long QT syndrome detected by electrocardiogram screening. Pediatrics international : official journal of the Japan Pediatric Society. 2023.01; 65 (1): e15481. ( PubMed, DOI )

  11. Chida-Nagai A, Masaki N, Maeda K, Sasaki K, Sato H, Muneuchi J, Ochiai Y, Murayama H, Tahara M, Shiono A, Shinozuka A, Kono F, Machida D, Toyooka S, Sugimoto S, Nakamura K, Akagi S, Kondo M, Kasahara S, Kotani Y, Koizumi J, Oda K, Harada M, Nakajima D, Murata A, Nagata H, Yatsunami K, Kobayashi T, Matsunaga Y, Inoue T, Yamagishi H, Nakagawa N, Ohtani K, Yamamoto M, Ito Y, Hokosaki T, Kuwahara Y, Masutani S, Nomura K, Wada T, Sawada H, Abiko M, Takahashi T, Ishikawa Y, Okada S, Naitoh A, Toda T, Ando T, Masuzawa A, Hoshino S, Kawada M, Nomura Y, Ueno K, Ohashi N, Tachibana T, Cao Y, Ueda H, Yanagi S, Koide M, Mitsushita N, Higashi K, Minosaki Y, Hayashi T, Okamoto T, Kuraishi K, Ehara E, Ishida H, Horigome H, Murakami T, Takei K, Ishii T, Harada G, Hirata Y, Maeda J, Tatebe S, Ota C, Hayabuchi Y, Sakazaki H, Sasaki T, Hirono K, Suzuki S, Yasuda M, Takeda A, Sawai M, Miyaji K, Kitagawa A, Nakai Y, Kakimoto N, Agematsu K, Manabe A, Saiki Y. Use of the index of pulmonary vascular disease for predicting long-term outcome of pulmonary arterial hypertension associated with congenital heart disease. Frontiers in cardiovascular medicine. 2023; 10 1212882. ( PubMed, DOI )

  12. Nakamura Arisa, Adachi Eriko, Matsubara Yohei, Ishii Taku, Hosokawa Susumu, Kashimada Kenichi, Takasawa Kei. 心電図スクリーニングで発見されたQT延長症候群例での副甲状腺機能低下症のモニタリング(Monitoring hypoparathyroidism in long QT syndrome detected by electrocardiogram screening) Pediatrics International. 2023; 65 (1): ped.15481. ( ichushi )

  13. Yamaguchi Y, Takasawa K, Irabu H, Hiratoko K, Ichigi Y, Hirata K, Tamura Y, Murakoshi M, Yamashita M, Nakatani H, Shimoda M, Ishii T, Udagawa T, Shimizu M, Kanegane H, Morio T. Infliximab treatment for refractory COVID-19-associated multisystem inflammatory syndrome in a Japanese child. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2022.01; ( PubMed, DOI )

  14. Ishii T, Nawa N, Morio T, Fujiwara T. Association between nationwide introduction of public-access defibrillation and sudden cardiac death in Japan: An interrupted time-series analysis. International journal of cardiology. 2021.12; ( PubMed, DOI )

  15. Iwasawa S, Uyeda T, Saito M, Ishii T, Inage A, Hamamichi Y, Yazaki S, Yoshikawa T. Efficacy and Safety of Low-Dose Amiodarone Therapy for Tachyarrhythmia in Congenital Heart Disease. Pediatric cardiology. 2018.06; 39 (5): 1016-1022. ( PubMed, DOI )

  16. Hosokawa S, Vanderpool RR, Ishii T, Nishiyama M, Doi S. What Causes Pulmonary Arterial Hypertension in Down Syndrome With Congenital Heart Disease? Circulation journal : official journal of the Japanese Circulation Society. 2018.05; 82 (6): 1513-1514. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Japanese association of congenital heart disease with pulmonary hypertension registry (JACPHR) study approved by Japan Agency for Medical Research and Development (AMED). 2025.03.23 中華人民共和国広東省

  2. Ishii Taku, Hosokawa Susumu, Sumitomo Naofumi, Ishida Hidekazu, Takatsuki Shinichi, Uchida Keiko, Fukushima Hiroyuki, Kogaki Shigetoyo, Yamagishi Hiroyuki, Doi Shozaburo. 先天性心疾患を伴う肺高血圧症の小児患者に対する薬物治療　日本全国レジストリからの知見(Pharmacological treatment for pediatric patients with congenital heart disease with pulmonary hypertension: Insights from nationwide registry in Japan). 日本小児循環器学会総会・学術集会抄録集 2024.07.01

  3. Sakurai Makito, Ishii Taku, Ihara Kensuke, Hosokawa Susumu. 低酸素誘発性肺高血圧症の発症におけるヘッジホッグシグナル伝達の病態生理学的役割(The Pathophysiological Role of Hedgehog Signaling for the Development of Hypoxia Induced Pulmonary Hypertension). 日本循環器学会学術集会抄録集 2024.03.01

  4. Taku Ishii, Keiko Uchida, Susumu Hosokawa, Hidekazu Ishida, Shinichi Takatsuki, Shigetoyo Kogaki, Kei Inai, Hiroyuki Fukushima, Hiroyuki Yamagishi, Shozaburo Doi. Baseline characteristic of pulmonary hypertension patients with congenital heart disease in Japan: Insights from Japanese association of congenital heart disease with pulmonary hypertension registry (JACPHR). PH Korea 2023 with 3rd EASOPH 2023.07.14 Incheon, Korea

  5. Yohei Yamaguchi, Susumu Hosokawa, Satoshi Nagahara, Ayako Nagashima-Otsuki, Taku Ishii, Tomoyuki Umemoto, Shozaburo Doi. How should we manage women with Kawasaki disease with giant coronary aneurysms who want a child? ~case reports~. The 13th International Kawasaki Disease Symposium 2021.10.29 Web

  6. 稲毛 章郎, 水野 直和, 吉敷 香菜子, 小林 匠, 石井 卓, 浜道 裕二, 上田 知実, 矢崎 諭, 嘉川 忠博. Feature tracking MR strainによる術後ファロー四徴症の右室心筋deformationと三尖弁変位の評価. 日本小児循環器学会雑誌 2018.07.01

  7. Inage Akio, Kishiki Kanako, Mizuno Naokazu, Ishii Taku, Uyeda Tomomi, Yazaki Satoshi. Feature tracking MR Programを用いて評価したファロー四徴症修復術後患者における右室心筋変形と三尖弁偏位(Evaluation of Right Ventricular Myocardial Deformation and Tricuspid Valve Displacement in Repaired Tetralogy of Fallot Using Feature Tracking MR Program). 日本循環器学会学術集会抄録集 2018.03.01

  8. Inage Akio, Kishiki Kanako, Mizuno Naokazu, Kobayashi Takumi, Ishii Taku, Hamamichi Yuuji, Ueda Tomomi, Yazaki Satoshi, Yoshikawa Tadahiro. ファロー四徴症再建手術後のRV心筋奇形の心臓MRIによる評価(Assess RV myocardial deformation in repaired tetralogy of Fallot by cardiac MRI). 日本小児科学会雑誌 2018.02.01

  9. 稲毛 章郎, 水野 直和, 齋藤 美香, 浜道 裕二, 石井 卓, 上田 知実, 嘉川 忠博, 矢崎 諭. Feature tracking磁気共鳴によって評価された右心系疾患における心筋機能障害の臨床的意義. 日本小児循環器学会雑誌 2017.07.01

  10. 稲毛 章郎, 水野 直和, 齋藤 美香, 浜道 裕二, 石井 卓, 上田 知実, 嘉川 忠博, 矢崎 諭. Feature tracking磁気共鳴ストレインによるFontan循環における右室型及び左室型単心室の心筋機能の比較. 日本小児循環器学会雑誌 2017.07.01

  11. 稲毛 章郎, 石井 卓, 上田 知実, 矢崎 諭. Feature tracking磁気共鳴ストレイン、ストレインレート、および壁運動遅延分析によるフォンタン術後の右室機能の生理学的評価(Assessment of Right Ventricular Function in Fontan Physiology Using Feature Tracking Magnetic Resonance Strain, Strain Rate and Wall Motion Delay). 日本循環器学会学術集会抄録集 2017.03.01

  12. 稲毛 章郎, 水野 直和, 齋藤 美香, 浜道 裕二, 石井 卓, 上田 知実, 矢崎 諭, 嘉川 忠博. フォンタン手術後における大動脈肺動脈側副血行発達因子についての検討(Development factors of aortopulmonary collaterals after Fontan completions). 日本小児科学会雑誌 2017.02.01

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