Personnel Information

写真a

AI Masumi


Job title

Professor

Graduating School 【 display / non-display

  • Tokyo Medical and Dental University, Faculty of Medicine, School of Medicine, 1995.03, Graduated

Degree 【 display / non-display

  • MD,PhD, Tokyo Medical and Dental University

Campus Career 【 display / non-display

  • 2013.07
    -
    Now
    Tokyo Medical and Dental University, Medical Hospital, Department of Insured Medical Care Management, Director and Professor, Department of Insured Medical Care Management
  • 2013.10
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Public Health, Insured Medical Care Management, Professor
  • 2013.05
    -
    2013.06
    Tokyo Medical and Dental University, Medical Hospital, Department of Insured Medical Care Management, Director, Department of Insured Medical Care Management
  • 2017.04
    -
    Now
    Tokyo Medical and Dental University, Medical Hospital, Director
  • 2018.08
    -
    Now
    Tokyo Medical and Dental University, Medical Hospital, Central Clinical Facilities, Medical Informatics, Director
  • 2011.04
    -
    2013.04
    Tokyo Medical and Dental University, Joint Institutes for Education and Research, Life Science and Bioethics Research Center, Department of Life Sciences and Medical Ethics, Junior Associate Professor
  • 2013.07
    -
    2017.03
    Tokyo Medical and Dental University, Medical Hospital, Department of Insured Medical Care Management, Professor
  • 2014.01
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Public Health, Insured Medical Care Management, Professor
  • 2017.04
    -
    2018.03
    Tokyo Medical and Dental University, Medical Hospital, Department of Insured Medical Care Management, Professor
  • 2018.04
    -
    2021.09
    Tokyo Medical and Dental University, Medical Hospital, Department of Insured Medical Care Management, Professor
  • 2021.10
    -
    Now
    Tokyo Medical and Dental University, Tokyo Medical and Dental University, Department of Insured Medical Care Management, Professor

▼display all

External Career 【 display / non-display

  • 2013.07
    -
    Now
    , Professor

Academic Society Affiliations 【 display / non-display

  • American Diabetes Association

  • American Heart Association

Research Areas 【 display / non-display

  • Metabolism and endocrinology

  • Hygiene and public health (laboratory)

  • Others

  • Cardiology

Qualification Acquired 【 display / non-display

  • Doctor

 

Research Theme 【 display / non-display

  • lipid metabolism, 1996.04 - Now

Published Papers & Misc 【 display / non-display

  1. Ogino M, Kameda T, Mutsuda Y, Tanaka H, Takahashi J, Okazaki M, Ai M, Ohkawa R. Development of internal standard for lipoprotein subclass analysis using dual detection gel-permeation high-performance liquid chromatography system. Bioscience reports. 2022.05; 42 (6): ( PubMed, DOI )

  2. Hayashi T, Ai M, Goto S, Nakamura M, Nagaike H, Suzuki R, Abe Y, Ohta M, Ito Y, Hirano T. Circadian Rhythm of Subspecies of Low-Density Lipoprotein-Cholesterol and High-Density Lipoprotein-Cholesterol in Healthy Subjects and Patients with Type 2 Diabetes. Journal of atherosclerosis and thrombosis. 2022.03; ( PubMed, DOI )

  3. Yokoyama Minato, Ishioka Junichiro, Toba Mikayo, Fukushima Hiroshi, Tanaka Hajime, Yoshida Soichiro, Matsuoka Yoh, Ai Masumi, Fushimi Kiyohide, Fujii Yasuhisa. Trends and safety of robot-assisted partial nephrectomy during the initial 2-year period after government approval in Japan: A nationwide database study from 2016 to 2018(和訳中) International Journal of Urology. 2021.12; 28 (12): 1268-1272. ( ichushi )

  4. Morimoto Nobuhisa, Urayama Kevin, Tanaka Akira, Ai Masumi. Relationship between dietary fibre to carbohydrate ratio and mortality risk in the NHANES INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2021.09; 50

  5. Yokoyama Shinji, Remaley Alan T., Sampson Maureen, Ai Masumi, Okazaki Mitsuyo. Validation by HPLC analyses of new equations for estimating cholesterol in plasma lipoprotein subfractions BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2021.09; 1866 (9): 158986. ( PubMed, DOI )

  6. Yokoyama Minato, Ishioka Junichiro, Toba Mikayo, Fukushima Hiroshi, Tanaka Hajime, Yoshida Soichiro, Matsuoka Yoh, Ai Masumi, Fushimi Kiyohide, Fujii Yasuhisa. Trends and safety of robot-assisted partial nephrectomy during the initial 2-year period after government approval in Japan: A nationwide database study from 2016 to 2018 INTERNATIONAL JOURNAL OF UROLOGY. 2021.09; 28 (12): 1268-1272. ( PubMed, DOI )

  7. Nakamura Marie, Yamamoto Yasushi, Imaoka Wataru, Kuroshima Toshio, Toragai Ryoko, Ito Yasuki, Kanda Eiichiro, Schaefer Ernst J., Ai Masumi. Relationships between Smoking Status, Cardiovascular Risk Factors, and Lipoproteins in a Large Japanese Population Journal of Atherosclerosis and Thrombosis. 2021.09; 28 (9): 942-953. ( ichushi )

  8. Ikezaki H., Nakashima R., Ai M., Okazaki M., Kohzuma T., Schaefer E. J.. RELATIONSHIP BETWEEN DIETARY VITAMIN D INTAKE, OBESITY, AND TWENTY LIPOPROTEIN SUBCLASSES: RESULTS FROM THE KYUSHU AND OKINAWA POPULATION STUDY (KOPS) ATHEROSCLEROSIS. 2021.08; 331 E163-E164.

  9. Kayamori Y, Nakamura M, Kishi K, Miida T, Nishimura K, Okamura T, Hirayama S, Ohmura H, Yoshida H, Ai M, Tanaka A, Sumino H, Murakami M, Inoue I, Teramoto T, Yokoyama S. Comparison of the Japan Society of Clinical Chemistry reference method and CDC method for HDL and LDL cholesterol measurements using fresh sera. Practical laboratory medicine. 2021.05; 25 e00228. ( PubMed, DOI )

  10. Nakamura Marie, Yamamoto Yasushi, Imaoka Wataru, Kuroshima Toshio, Toragai Ryoko, Ito Yasuki, Kanda Eiichiro, Schaefer Ernst J., Ai Masumi. Relationships between Smoking Status, Cardiovascular Risk Factors, and Lipoproteins in a Large Japanese Population JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS. 2021; 28 (9): 942-953. ( PubMed, DOI )

  11. Ikezaki Hiroaki, Furusyo Norihiro, Yokota Yuya, Ai Masumi, Asztalos Bela F., Murata Masayuki, Hayashi Jun, Schaefer Ernst J.. Small Dense Low-Density Lipoprotein Cholesterol and Carotid Intimal Medial Thickness Progression Journal of Atherosclerosis and Thrombosis. 2020.10; 27 (10): 1108-1122. ( ichushi )

  12. Kitazawa Toru, Seino Hiroaki, Ohashi Hiroshi, Inazawa Takeshi, Inoue Masahiro, Ai Masumi, Fujishiro Midori, Kuroda Hisamoto, Yamada Masayo, Anai Motonobu, Ishihara Hisamitsu. Comparison of tofogliflozin versus glimepiride as the third oral agent added to metformin plus a dipeptidyl peptidase-4 inhibitor in Japanese patients with type 2 diabetes: A randomized, 24-week, open-label, controlled trial (STOP-OB) DIABETES OBESITY & METABOLISM. 2020.09; 22 (9): 1659-1663. ( PubMed, DOI )

  13. Hsu Hung, Hsu Powen, Cheng Ming-Hui, Ito Yasuki, Kanda Eiichiro, Schaefer Ernst J., Ai Masumi. 台湾における糖尿病前症および糖尿病におけるリポ蛋白質亜分画とグルコース恒常性(Lipoprotein Subfractions and Glucose Homeostasis in Prediabetes and Diabetes in Taiwan) Journal of Atherosclerosis and Thrombosis. 2019.10; 26 (10): 890-914. ( ichushi )

  14. Ikezaki Hiroaki, Fisher Virginia A., Lim Elise, Ai Masumi, Liu Ching-Ti, Cupples L. Adrienne, Nakajima Katsuyuki, Asztalos Bela F., Furusyo Norihiro, Schaefer Ernst J.. Direct Versus Calculated LDL Cholesterol and C-Reactive Protein in Cardiovascular Disease Risk Assessment in the Framingham Offspring Study CLINICAL CHEMISTRY. 2019.09; 65 (9): 1102-1114. ( PubMed, DOI )

  15. Kitazawa T., Seino H., Ohashi H., Inazawa T., Inoue M., Ai M., Fujishiro M., Kuroda H., Yamada M., Anai M., Ishihara H.. Tofogliflozin is a better candidate than glimepiride for the third line oral agent added to the metformin plus DPP-4 inhibitor dual therapy: results of a randomised control trial DIABETOLOGIA. 2019.09; 62 S359.

  16. Shingai Masumi, Niijima Ren, Kobayashi Yuto, Miyadera Ryosuke, Murayama Akihiko, Mukai Shinji. 3D motion captureを用いた主観的な椅子着座姿勢の特徴 20代の理学療法士によって感じ取られた椅子着座姿勢の認識(Characteristics of Subjective Chair Sitting Posture Using 3D Motion Capture: Recognition of a Chair Sitting Posture Felt By a 20's Physical Therapist) Journal of Physical Therapy Science. 2019.07; 31 (Suppl.1): 7. ( ichushi )

  17. Ikezaki Hiroaki, Furusyo Norihiro, Yokota Yuya, Ai Masumi, Bela Asztalos, Murata Masayuki, Hayashi Jun, Ernst Schaefer. Small dense LDLコレステロールによる頸動脈内膜中膜肥厚の進行予測(Small Dense Low Density Lipoprotein Cholesterol Predict Carotid Intimal Medial Thickness Progression) 日本動脈硬化学会総会プログラム・抄録集. 2019.07; 51回 2-P. ( ichushi )

  18. Schaefer Ernst J., Ikezaki Hiroaki, Ai Masumi, Nakajima Katsuyuki, Cupples L. Adrienne. Framingham第2世代コホート研究における心血管疾患の予測(The Prediction of Cardiovascular Disease in the Framingham Offspring Study) 日本動脈硬化学会総会プログラム・抄録集. 2019.07; 51回 STML-1. ( ichushi )

  19. Hung Hsu, Powen Hsu, Ming-Hui Cheng, Yasuki Ito, Eiichiro Kanda, Ernst J Schaefer, Masumi Ai. Lipoprotein Subfractions and Glucose Homeostasis in Prediabetes and Diabetes in Taiwan. J. Atheroscler. Thromb.. 2019.02; 26 (10): 890-914. ( PubMed, DOI )

  20. Hisamitsu Ishihara, Motonobu Anai, Hiroaki Seino, Toru Kitazawa, Hiroshi Ohashi, Masumi Ai, Masahiro Inoue, Midori Fujishiro, Takeshi Inazawa, Hisamoto Kuroda, Masayo Yamada. Rationale and Design of the STOP-OB Study for Evaluating the Effects of Tofogliflozin and Glimepiride on Fat Deposition in Type 2 Diabetes Patients Treated with Metformin/DPP-4 Inhibitor Dual Therapy. Diabetes Ther. 2018.10; 9 (5): 2117-2125. ( PubMed, DOI )

  21. Ai Masumi, Yamamoto Yasushi, Toragai Ryoko, Kuroshima Toshio, Morimoto Nobuhisa, Kanda Eiichiro, Imaoka Wataru. REFERENCE RANGE OF SERUM CONCENTRATION OF SMALL DENSE LDL CHOLESTEROL FOR HEALTH CHECK-UP ATHEROSCLEROSIS SUPPLEMENTS. 2018.06; 32 55.

  22. Hiromasa Goto, Tomoya Mita, Yoshio Fujitani, Shimpei Fujimoto, Kiyohito Takahashi, Hiroaki Satoh, Takahisa Hirose, Toru Hiyoshi, Masumi Ai, Yosuke Okada, Hideki Nishimura, Hisamoto Kuroda, Toshiki Matsubara, Masahiko Gosho, Hitoshi Ishii, Hirotaka Watada. Effects of linagliptin versus voglibose on treatment-related quality of life in patients with type 2 diabetes: sub-analysis of the L-STEP study. Endocr. J.. 2018.04; 65 (6): 657-668. ( PubMed, DOI )

  23. Nobuhisa Morimoto, Chikako Kasuga, Airi Tanaka, Keiko Kamachi, Masumi Ai, Kevin Y Urayama, Akira Tanaka. Association between dietary fibre:carbohydrate intake ratio and insulin resistance in Japanese adults without type 2 diabetes. Br. J. Nutr.. 2018.03; 119 (6): 620-628. ( PubMed, DOI )

  24. Kawamura Hiroshi, Hsu Powen, Kanda Eiichiro, Kohzuma Takuji, Ai Masumi. 2型糖尿病(T2DM)に対する将来の血糖管理のための指標としてのグリコアルブミン(GA)/ヘモグロビンA1c(HbA1c)(GA/HbA1c indicator for future glycemic control for T2DM) 日本動脈硬化学会総会プログラム・抄録集. 2017.06; 49回 266. ( ichushi )

  25. Anne P Beigneux, Kazuya Miyashita, Michael Ploug, Dirk J Blom, Masumi Ai, MacRae F Linton, Weerapan Khovidhunkit, Robert Dufour, Abhimanyu Garg, Maureen A McMahon, Clive R Pullinger, Norma P Sandoval, Xuchen Hu, Christopher M Allan, Mikael Larsson, Tetsuo Machida, Masami Murakami, Karen Reue, Peter Tontonoz, Ira J Goldberg, Philippe Moulin, Sybil Charrière, Loren G Fong, Katsuyuki Nakajima, Stephen G Young. Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia. N. Engl. J. Med.. 2017.04; 376 (17): 1647-1658. ( PubMed, DOI )

  26. Hiroaki Ikezaki, Masumi Ai, Ernst J Schaefer, Seiko Otokozawa, Bela F Asztalos, Katsuyuki Nakajima, Yanhua Zhou, Ching-Ti Liu, Paul F Jacques, L Adrienne Cupples, Norihiro Furusyo. Cardiovascular disease prevalence and insulin resistance in the Kyushu-Okinawa Population Study and the Framingham Offspring Study. J Clin Lipidol. 2017.02; 11 (2): 348-356. ( PubMed, DOI )

  27. Eiichiro Kanda, Masumi Ai, Mitsuyo Okazaki, Masayuki Yoshida, Yoshitaka Maeda. Association of High-Density Lipoprotein Subclasses with Chronic Kidney Disease Progression, Atherosclerosis, and Klotho. PLoS ONE. 2016.11; 11 (11): e0166459. ( PubMed, DOI )

  28. Yoshio Fujitani, Shimpei Fujimoto, Kiyohito Takahashi, Hiroaki Satoh, Takahisa Hirose, Toru Hiyoshi, Masumi Ai, Yosuke Okada, Masahiko Gosho, Tomoya Mita, Hirotaka Watada. Effects of linagliptin monotherapy compared with voglibose on postprandial blood glucose responses in Japanese patients with type 2 diabetes: Linagliptin Study of Effects on Postprandial blood glucose (L-STEP). Diabetes Res. Clin. Pract.. 2016.11; 121 146-156. ( PubMed, DOI )

  29. Hiroaki Ikezaki, Masumi Ai, Ernst J Schaefer, Seiko Otokozawa, Bela F Asztalos, Katsuyuki Nakajima, Yanhua Zhou, Ching-Ti Liu, Paul F Jacques, L Adrienne Cupples, Norihiro Furusyo. Ethnic Differences in Glucose Homeostasis Markers between the Kyushu-Okinawa Population Study and the Framingham Offspring Study. Sci Rep. 2016.11; 6 36725. ( PubMed, DOI )

  30. Powen Hsu, Masumi Ai, Eiichiro Kanda, Neng-Chun Yu, Hsiao-Lien Chen, Huan-Wen Chen, Ming-Hui Cheng, Takuji Kohzuma, Ernst J Schaefer, Masayuki Yoshida. A comparison of glycated albumin and glycosylated hemoglobin for the screening of diabetes mellitus in Taiwan. Atherosclerosis. 2015.09; 242 (1): 327-333. ( PubMed, DOI )

  31. Hiroaki Ikezaki, Norihiro Furusyo, Takeshi Ihara, Takeo Hayashi, Kazuya Ura, Satoshi Hiramine, Fujiko Mitsumoto, Koji Takayama, Masayuki Murata, Takuji Kohzuma, Masumi Ai, Ernst J Schaefer, Jun Hayashi. Glycated albumin as a diagnostic tool for diabetes in a general Japanese population. Metab. Clin. Exp.. 2015.06; 64 (6): 698-705. ( PubMed, DOI )

  32. Takashi Miida, Kunihiro Nishimura, Tomonori Okamura, Satoshi Hirayama, Hirotoshi Ohmura, Hiroshi Yoshida, Yoh Miyashita, Masumi Ai, Akira Tanaka, Hiroyuki Sumino, Masami Murakami, Ikuo Inoue, Yuzo Kayamori, Masakazu Nakamura, Tsutomu Nobori, Yukihisa Miyazawa, Tamio Teramoto, Shinji Yokoyama. Validation of homogeneous assays for HDL-cholesterol using fresh samples from healthy and diseased subjects. Atherosclerosis. 2014.03; 233 (1): 253-259. ( PubMed, DOI )

  33. Katsuyuki Nakajima, Takeaki Nagamine, Masaki Q Fujita, Masumi Ai, Akira Tanaka, Ernst Schaefer. Apolipoprotein B-48: a unique marker of chylomicron metabolism. Adv Clin Chem. 2014; 64 117-177. ( PubMed )

  34. Eiichiro Kanda, Masumi Ai, Renjiro Kuriyama, Masayuki Yoshida, Tatsuo Shiigai. Dietary acid intake and kidney disease progression in the elderly. Am. J. Nephrol.. 2014; 39 (2): 145-152. ( PubMed, DOI )

  35. Norihiro Furusyo, Masumi Ai, Mitsuyo Okazaki, Hiroaki Ikezaki, Takeshi Ihara, Takeo Hayashi, Satoshi Hiramine, Kazuya Ura, Takuji Kohzuma, Ernst J Schaefer, Jun Hayashi. Serum cholesterol and triglyceride reference ranges of twenty lipoprotein subclasses for healthy Japanese men and women. Atherosclerosis. 2013.12; 231 (2): 238-245. ( PubMed, DOI )

  36. Eiichiro Kanda, Masumi Ai, Asami Iwamoto, Mitsuyo Okazaki, Yoshitaka Maeda, Sei Sasaki, Masayuki Yoshida. Relationship between Icodextrin use and decreased level of small low-density lipoprotein cholesterol fractioned by high-performance gel permeation chromatography. BMC Nephrol. 2013; 14 234. ( PubMed, DOI )

  37. Eiichiro Kanda, Masumi Ai, Mitsuyo Okazaki, Yoshitaka Maeda, Sei Sasaki, Masayuki Yoshida. The association of very-low-density lipoprotein with ankle-brachial index in peritoneal dialysis patients with controlled serum low-density lipoprotein cholesterol level. BMC Nephrol. 2013; 14 212. ( PubMed, DOI )

  38. Kanda E, Ai M, Yoshida M, Kuriyama R, Shiigai T. High serum bicarbonate level within the normal range prevents the progression of chronic kidney disease in elderly chronic kidney disease patients. BMC Nephrol. 2013; 14 4. ( PubMed, DOI )

  39. Miida T, Nishimura K, Okamura T, Hirayama S, Ohmura H, Yoshida H, Miyashita Y, Ai M, Tanaka A, Sumino H, Murakami M, Inoue I, Kayamori Y, Nakamura M, Nobori T, Miyazawa Y, Teramoto T, Yokoyama S. A multicenter study on the precision and accuracy of homogeneous assays for LDL-cholesterol: comparison with a beta-quantification method using fresh serum obtained from non-diseased and diseased subjects. Atherosclerosis. 2012.11; 225 (1): 208-215. ( PubMed, DOI )

  40. Ai M. [Atherosclerosis (hypertension)]. Nippon Rinsho. 2012.05; 70 (5): 840-845. ( PubMed )

  41. Furusyo N, Koga T, Ai M, Otokozawa S, Kohzuma T, Ikezaki H, Schaefer EJ, Hayashi J. Plasma glycated albumin level and atherosclerosis: Results from the Kyushu and Okinawa Population Study (KOPS). International journal of cardiology. 2012.05; ( PubMed, DOI )

  42. van Himbergen TM, Beiser AS, Ai M, Seshadri S, Otokozawa S, Au R, Thongtang N, Wolf PA, Schaefer EJ. Biomarkers for Insulin Resistance and Inflammation and the Risk for All-Cause Dementia and Alzheimer Disease: Results From the Framingham Heart Study. Archives of neurology. 2012.01; ( PubMed, DOI )

  43. Furusyo N, Koga T, Ai M, Otokozawa S, Kohzuma T, Ikezaki H, Schaefer EJ, Hayashi J. Utility of glycated albumin for the diagnosis of diabetes mellitus in a Japanese population study: results from the Kyushu and Okinawa Population Study (KOPS). Diabetologia. 2011.09; ( PubMed, DOI )

  44. Ai M, Otokozawa S, Asztalos BF, White CC, Cupples LA, Nakajima K, Lamon-Fava S, Wilson PW, Matsuzawa Y, Schaefer EJ. Adiponectin: An independent risk factor for coronary heart disease in men in the Framingham offspring Study. Atherosclerosis. 2011.08; 217 (2): 543-548. ( PubMed, DOI )

  45. Nakajima K, Nakano T, Tokita Y, Nagamine T, Inazu A, Kobayashi J, Mabuchi H, Stanhope KL, Havel PJ, Okazaki M, Ai M, Tanaka A. Postprandial lipoprotein metabolism: VLDL vs chylomicrons. Clin Chim Acta. 2011.07; 412 (15-16): 1306-1318. ( PubMed, DOI )

  46. Schaefer EJ, Otokozawa S, Ai M. Limitations of direct methods and the reference method for measuring HDL and LDL cholesterol. Clin Chem. 2011.07; 57 (7): 1081-3; author reply 1083. ( PubMed, DOI )

  47. Thongtang N, Ai M, Otokozawa S, Himbergen TV, Asztalos BF, Nakajima K, Stein E, Jones PH, Schaefer EJ. Effects of maximal atorvastatin and rosuvastatin treatment on markers of glucose homeostasis and inflammation. Am J Cardiol. 2011.02; 107 (3): 387-392. ( PubMed, DOI )

  48. Ai M, Yoshida M. [Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study]. Nippon Rinsho. 2010.11; 68 Suppl 9 285-290. ( PubMed )

  49. Otokozawa S, Ai M, Asztalos BF, White CC, Demissie-Banjaw S, Cupples LA, Nakajima K, Wilson PW, Schaefer EJ. Direct assessment of plasma low density lipoprotein and high density lipoprotein cholesterol levels and coronary heart disease: results from the Framingham Offspring Study. Atherosclerosis. 2010.11; 213 (1): 251-255. ( PubMed, DOI )

  50. Nakajima K, Kobayashi J, Mabuchi H, Nakano T, Tokita Y, Nagamine T, Imamura S, Ai M, Otokozawa S, Schaefer EF. Association of angiopoietin-like protein 3 with hepatic triglyceride lipase and lipoprotein lipase activities in human plasma. Ann Clin Biochem. 2010.09; 47 (Pt 5): 423-431. ( PubMed, DOI )

  51. Asztalos BF, Swarbrick MM, Schaefer EJ, Dallal GE, Horvath KV, Ai M, Stanhope KL, Austrheim-Smith I, Wolfe BM, Ali M, Havel PJ. Effects of weight loss, induced by gastric bypass surgery, on HDL remodeling in obese women. J Lipid Res. 2010.08; 51 (8): 2405-2412. ( PubMed, DOI )

  52. Vega-López S, Matthan NR, Ausman LM, Harding SV, Rideout TC, Ai M, Otokozawa S, Freed A, Kuvin JT, Jones PJ, Schaefer EJ, Lichtenstein AH. Altering dietary lysine:arginine ratio has little effect on cardiovascular risk factors and vascular reactivity in moderately hypercholesterolemic adults. Atherosclerosis. 2010.06; 210 (2): 555-562. ( PubMed, DOI )

  53. Ai M, Otokozawa S, Asztalos BF, Ito Y, Nakajima K, White CC, Cupples LA, Wilson PW, Schaefer EJ. Small dense LDL cholesterol and coronary heart disease: results from the Framingham Offspring Study. Clin Chem. 2010.06; 56 (6): 967-976. ( PubMed, DOI )

  54. Otokozawa S, Ai M, Diffenderfer MR, Asztalos BF, Tanaka A, Lamon-Fava S, Schaefer EJ. Fasting and postprandial apolipoprotein B-48 levels in healthy, obese, and hyperlipidemic subjects Metabolism. 2009; 58 (11): 1536-1542. ( PubMed, DOI )

  55. van Himbergen TM, Matthan NR, Resteghini NA, Otokozawa S, Ai M, Stein EA, Jones PH, Schaefer EJ. Comparison of the effects of maximal dose atorvastatin and rosuvastatin therapy on cholesterol synthesis and absorption markers J Lipid Res. 2009; 50 (4): 730-739. ( PubMed, DOI )

  56. Ai M, Otokozawa S, Schaefer EJ, Asztalos BF, Nakajima K, Shrader P, Kathiresan S, Meigs JB, Williams G, Nathan DM. Glycated albumin and direct low density lipoprotein cholesterol levels in type 2 diabetes mellitus Clin Chim Acta. 2009; 406 (1-2): 71-74. ( PubMed, DOI )

  57. Vega-López S, Matthan NR, Ausman LM, Ai M, Otokozawa S, Schaefer EJ, Lichtenstein AH. Substitution of vegetable oil for a partially-hydrogenated fat favorably alters cardiovascular disease risk factors in moderately hypercholesterolemic postmenopausal women Atherosclerosis. 2009; 207 (1): 208-212. ( PubMed, DOI )

  58. Otokozawa S, Ai M, Van Himbergen T, Asztalos BF, Tanaka A, Stein EA, Jones PH, Schaefer EJ. Effects of intensive atorvastatin and rosuvastatin treatment on apolipoprotein B-48 and remnant lipoprotein cholesterol levels Atherosclerosis. 2009; 205 (1): 197-201. ( PubMed, DOI )

  59. van Himbergen TM, Otokozawa S, Matthan NR, Schaefer EJ, Buchsbaum A, Ai M, van Tits LJ, de Graaf J, Stalenhoef AF. Familial Combined Hyperlipidemia Is Associated With Alterations in the Cholesterol Synthesis Pathway Arterioscler Thromb Vasc Biol. 2009; ( PubMed, DOI )

  60. Ai M, Tanaka A, Shimokado K, Ohtani R, Inazu A, Kobayashi J, Mabuchi H, Nakano T, Nakajima K. A deficiency of cholesteryl ester transfer protein whose serum remnant-like particle-triglyceride significantly increased, but serum remnant-like particle-cholesterol did not after an oral fat load Ann Clin Biochem. 2009; 46 (Pt 6): 457-463. ( PubMed, DOI )

  61. Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer AA, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W, McGahan JP, Seibert A, Krauss RM, Chiu S, Schaefer EJ, Ai M, Otokozawa S, Nakajima K, Nakano T, Beysen C, Hellerstein MK, Berglund L, Havel PJ. Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans J Clin Invest. 2009; 119 (5): 1322-1334. ( PubMed, DOI )

  62. Asztalos BF, Swarbrick MM, Schaefer EJ, Dallal GE, Horvath KV, Ai M, Stanhope KL, Austrheim-Smith I, Wolfe BM, Ali M, Havel PJ. Effects of weight loss, induced by gastric bypass surgery, on HDL remodeling in obese women J Lipid Res. 2009; ( PubMed, DOI )

  63. Ogita K, Ai M, Tanaka A, Ito Y, Hirano T, Yoshino G, Shimokado K. Serum concentration of small dense low-density lipoprotein-cholesterol during oral glucose tolerance test and oral fat tolerance test Clin Chim Acta. 2008; 387 (1-2): 36-41. ( PubMed, DOI )

  64. Chiba T, Shinozaki S, Nakazawa T, Kawakami A, Ai M, Kaneko E, Kitagawa M, Kondo K, Chait A, Shimokado K. Leptin deficiency suppresses progression of atherosclerosis in apoE-deficient mice Atherosclerosis. 2008; 196 (1): 68-75. ( PubMed, DOI )

  65. Ai M, Otokozawa S, Asztalos BF, Nakajima K, Stein E, Jones PH, Schaefer EJ. Effects of maximal doses of atorvastatin versus rosuvastatin on small dense low-density lipoprotein cholesterol levels Am J Cardiol. 2008; 101 (3): 315-318. ( PubMed, DOI )

  66. Lamon-Fava S, Diffenderfer MR, Barrett PH, Buchsbaum A, Nyaku M, Horvath KV, Asztalos BF, Otokozawa S, Ai M, Matthan NR, Lichtenstein AH, Dolnikowski GG, Schaefer EJ. Extended-release niacin alters the metabolism of plasma apolipoprotein (Apo) A-I and ApoB-containing lipoproteins Arterioscler Thromb Vasc Biol. 2008; 28 (9): 1672-1678. ( PubMed, DOI )

  67. Ai M, Tanaka A, Shoji K, Ogita K, Hase T, Tokimitsu I, Shimokado K. Suppressive effects of diacylglycerol oil on postprandial hyperlipidemia in insulin resistance and glucose intolerance Atherosclerosis. 2007; 195 (2): 398-403. ( PubMed, DOI )

  68. Shinozaki S, Chiba T, Kokame K, Miyata T, Ai M, Kawakami A, Kaneko E, Yoshida M, Shimokado K. Site-specific effect of estradiol on gene expression in the adipose tissue of ob/ob mice Horm Metab Res. 2007; 39 (3): 192-196. ( PubMed, DOI )

  69. Asano T, Kaneko E, Shinozaki S, Imai Y, Shibayama M, Chiba T, Ai M, Kawakami A, Asaoka H, Nakayama T, Mano Y, Shimokado K. Hyperbaric oxygen induces basic fibroblast growth factor and hepatocyte growth factor expression, and enhances blood perfusion and muscle regeneration in mouse ischemic hind limbs Circ J. 2007; 71 (3): 405-411. ( PubMed )

  70. Abe Y, Ai M, Kaneko M, Sawara M, Nagano K, Shimokado K. [Studies on factors related to delayed discharge of elderly patients from university hospitals] Nippon Ronen Igakkai Zasshi. 2007; 44 (5): 641-647. ( PubMed )

  71. Imai Y, Kaneko E, Asano T, Kumagai M, Ai M, Kawakami A, Kataoka K, Shimokado K. A novel contrast medium detects increased permeability of rat injured carotid arteries in magnetic resonance T2 mapping imaging J Atheroscler Thromb. 2007; 14 (2): 65-71. ( PubMed )

  72. Ogita K, Ai M, Tanaka A, Ito Y, Hirano T, Yoshino G, Shimokado K. Circadian rhythm of serum concentration of small dense low-density lipoprotein cholesterol Clin Chim Acta. 2007; 376 (1-2): 96-100. ( PubMed, DOI )

  73. Ai M, Tanaka A, Ogita K, Shimokado K. Favorable effects of early insulin secretion by nateglinide on postprandial hyperlipidemia in patients with type 2 diabetes Diabetes Care. 2006; 29 (5): 1180. ( PubMed, DOI )

  74. Ai M, Tanaka A, Baba T, Yui K, Numano F. Increased cholesteryl ester transfer protein and changes in lipid metabolism from initiating insulin therapy Ann N Y Acad Sci. 2001; 947 356-361. ( PubMed )

  75. Tanaka A, AI M, Kobayashi Y, Tamura M, Shimokado K, Numano F. Metabolism of triglyceride-rich lipoproteins and their role in atherosclerosis Ann N Y Acad Sci. 2001; 947 207-12; discussion 212-3. ( PubMed )

  76. Ai M, Tanaka A. [Guidelines for plasma lipid and lipoprotein concentration] Nippon Rinsho. 2001; 59 Suppl 2 759-762. ( PubMed )

  77. Ai M, Tanaka A, Ogita K, Sekinc M, Numano F, Numano F, Reaven GM. Relationship between plasma insulin concentration and plasma remnant lipoprotein response to an oral fat load in patients with type 2 diabetes J Am Coll Cardiol. 2001; 38 (6): 1628-1632. ( PubMed )

  78. Ai M, Tanaka A, Tomie N, Ogita K, Sekine M, Numano F, Numano F. Triglyceride-rich lipoprotein cholesterol exceeds low-density lipoprotein cholesterol in hypertriglyceridemia patients Horm Metab Res. 2001; 33 (10): 612-617. ( PubMed, DOI )

  79. Tanaka A, Ai M. [Hyper-remnant-like particles (RLP) lipoproteinemia] Nippon Rinsho. 2001; 59 Suppl 3 107-111. ( PubMed )

  80. Tanaka A, Ai M. [Hyperlipidemia, definition, cause, frequency] Nippon Rinsho. 2001; 59 Suppl 2 653-660. ( PubMed )

  81. Tanaka A, Ai M. [Receptor for apolipoprotein B48] Nippon Rinsho. 2001; 59 Suppl 2 339-343. ( PubMed )

  82. Ai M, Tanaka A, Ogita K, Sekine M, Numano F, Numano F, Reaven GM. Relationship between hyperinsulinemia and remnant lipoprotein concentrations in patients with impaired glucose tolerance J Clin Endocrinol Metab. 2000; 85 (10): 3557-3560. ( PubMed )

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Conference Activities & Talks 【 display / non-display

  1. Ogino M., Kameda, Mutsuda Y., Tanaka H., Takahashi J., Okazaki M., Ai M., and Ohkawa R. Development of internal standard for lipoprotein subclass analysis using dual detection gel-permeation HPLC system. American Association for Clinical Chemistry (AACC) 2022 AACC Annual Scientific Meeting & Clinical Lab Expo 2022.07.26 Chicago

Others 【 display / non-display

  • 2011.04

    IRB Member, Tokyo Institute of Technology 2011-2017

  • IRB Member, Sony Corporation 2012-