Personnel Information

写真a

KINOWAKI Yuko


Job title

Assistant Professor
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Campus Career 【 display / non-display 】

  • 2014.04
    -
    2018.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Advanced Therapeutic Sciences， Comprehensive Pathology， Graduate Student
  • 2018.04
    -
    2021.03
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Central Clinical Facilities， Pathology， Assistant Professor
  • 2019.04
    -
    2021.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Advanced Therapeutic Sciences， Surgical Pathology， Assistant Professor
  • 2021.04
    -
    2024.09
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Advanced Therapeutic Sciences， Comprehensive Pathology， Assistant Professor
  • 2024.10
    -
    Now
    Institute of Science Tokyo， -， Graduate Schools， Advanced Therapeutic Sciences， Department of Comprehensive Pathology， Assistant Professor
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Research Areas 【 display / non-display 】

  • Human pathology

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Published Papers & Misc 【 display / non-display 】

  1. Kobayashi, M; Katsuda, H; Maekawa, A; Akahoshi, K; Watanabe, R; Kinowaki, Y; Nishimura, H; Fujiwara, T; Tanabe, M; Okamoto, R. Development of an intraductal papillary mucinous neoplasm malignancy prediction scoring system PLOS ONE. 2024.10; 19 (10): e0312234. ( PubMed, DOI )

  2. Kobayashi M, Niimi M, Katsuda H, Akahoshi K, Kinowaki Y, Sasaki M, Hirakawa A, Tateishi U, Tanabe M, Okamoto R. Optimization of Endoscopic Ultrasound Characteristics in the Diagnosis of Malignant Intraductal Papillary Mucinous Neoplasm. Pancreas. 2024.07; 53 (6): e521-e527. ( PubMed, DOI )

  3. Suzuki T, Hayakawa Y, Kaneko S, Takenaka K, Watakabe K, Kinowaki Y, Takemoto A, Ohtsuka K, Asahina Y, Okamoto R. Granulomatous hepatitis with Crohn's disease: a case report. Clinical journal of gastroenterology. 2024.06; 17 (3): 551-556. ( PubMed, DOI )

  4. Suzuki Tatsuya, Hayakawa Yuka, Kaneko Shun, Takenaka Kento, Watanabe Keiya, Kinowaki Yuko, Takemoto Akira, Ohtsuka Kazuo, Asahina Yasuhiro, Okamoto Ryuichi. クローン病を合併した肉芽腫様肝炎　1症例報告(Granulomatous hepatitis with Crohn's disease: a case report) Clinical Journal of Gastroenterology. 2024.06; 17 (3): 551-556. ( ichushi )

  5. Asakawa A, Yoshimoto R, Kobayashi M, Izumi N, Maejima T, Deguchi T, Kubota K, Takahashi H, Yamada M, Ishibashi S, Onishi I, Kinowaki Y, Kurata M, Kobayashi M, Ishibashi H, Okubo K, Ohashi K, Kitagawa M, Yamamoto K. The Comprehensive Characterization of B7-H3 Expression in the Tumor Microenvironment of Lung Squamous Cell Carcinoma: A Retrospective Study. Cancers. 2024.06; 16 (11): ( PubMed, DOI )

  6. Kawade, G; Kurata, M; Matsuki, Y; Fukuda, S; Onishi, I; Kinowaki, Y; Watabe, S; Ishibashi, S; Ikeda, M; Yamamoto, M; Ohashi, K; Kitagawa, M; Yamamoto, K. Mediation of Ferroptosis Suppressor Protein 1 Expression via 4-Hydroxy-2-Nonenal Accumulation Contributes to Acquisition of Resistance to Apoptosis and Ferroptosis in Diffuse Large B-Cell Lymphoma LABORATORY INVESTIGATION. 2024.04; 104 (4): 102027. ( PubMed, DOI )

  7. Maruyama Soichi, Furusawa Haruhiko, Endo Satoshi, Kumagai Takashi, Mitsumura Takahiro, Shimada Sho, Yamana Takashi, Sakakibara Rie, Iijima Yuki, Shibata Sho, Honda Takayuki, Shirai Tsuyoshi, Okamoto Tsukasa, Tateishi Tomoya, Tamaoka Meiyo, Kinowaki Yuko, Ishibashi Hironori, Okubo Kenichi, Miyazaki Yasunari. 非結核性抗酸菌症患者における肺動脈瘤(Pulmonary Artery Aneurysm in a Patient with Nontuberculous Mycobacteria Infection) Internal Medicine. 2024.04; 63 (7): 989-992. ( ichushi )

  8. Maruyama S, Furusawa H, Endo S, Kumagai T, Mitsumura T, Shimada S, Yamana T, Sakakibara R, Iijima Y, Shibata S, Honda T, Shirai T, Okamoto T, Tateishi T, Tamaoka M, Kinowaki Y, Ishibashi H, Okubo K, Miyazaki Y. Pulmonary Artery Aneurysm in a Patient with Nontuberculous Mycobacteria Infection. Internal medicine (Tokyo, Japan). 2024.04; 63 (7): 989-992. ( PubMed, DOI )

  9. Kinowaki Y, Fukumura Y, Kawade G, Sugita K, Kinowaki K, Akahoshi K, Kobayashi M, Ono H, Kudo A, Tanabe M, Akashi T, Ohashi K, Kurata M. Gene expression profiling of pancreatic neuroendocrine carcinoma and mixed neuroendocrine-non-neuroendocrine neoplasm. Gene. 2024.01; 893 147916. ( PubMed, DOI )

  10. Watabe S, Aruga Y, Kato R, Kawade G, Kubo Y, Tatsuzawa A, Onishi I, Kinowaki Y, Ishibashi S, Ikeda M, Fukawa Y, Akahoshi K, Tanabe M, Kurata M, Ohashi K, Kitagawa M, Yamamoto K. Regulation of 4-HNE via SMARCA4 Is Associated with Worse Clinical Outcomes in Hepatocellular Carcinoma. Biomedicines. 2023.08; 11 (8): ( PubMed, DOI )

  11. Yagi K, Ono H, Kudo A, Kinowaki Y, Asano D, Watanabe S, Ishikawa Y, Ueda H, Akahoshi K, Tanaka S, Tanabe M. MGMT is frequently inactivated in pancreatic NET-G2 and is associated with the therapeutic activity of STZ-based regimens. Sci Rep. 2023.05; 13 (1): 7535. ( PubMed, DOI )

  12. Hata C, Fukawa Y, Motoi T, Kinowaki Y, Akashi T, Ohashi K, Ishikawa Y, Waseda Y, Fujii Y, Kakuta R, Ikeda S, Onishi I. A Primary Kidney Giant Cell Tumor of Soft Tissue Caused Peritoneal Dissemination, Considered to Be Malignant Transformation: A Case Report. Diagnostics (Basel, Switzerland). 2023.02; 13 (4): ( PubMed, DOI )

  13. Usui E, Kanno Y, Yonetsu T, Kinowaki Y, Akashi T, Sasano T. Multimodality Imaging of Possible Healed Plaque Erosion Pathologically Validated by Directional Coronary Atherectomy Specimens. JACC. Cardiovascular interventions. 2022.11; 15 (21): 2225-2227. ( PubMed, DOI )

  14. Shinohara H, Kobayashi M, Hayashi K, Nogawa D, Asakawa A, Ohata Y, Kubota K, Takahashi H, Yamada M, Tokunaga M, Kinugasa Y, Oda G, Nakagawa T, Onishi I, Kinowaki Y, Kurata M, Ohashi K, Kitagawa M, Yamamoto K. Spatial and Quantitative Analysis of Tumor-Associated Macrophages: Intratumoral CD163-/PD-L1+ TAMs as a Marker of Favorable Clinical Outcomes in Triple-Negative Breast Cancer. International journal of molecular sciences. 2022.10; 23 (21): ( PubMed, DOI )

  15. Kato T, Kudo A, Kinowaki Y, Ishikawa Y, Watanabe S, Akahoshi K, Ogawa K, Ono H, Ban D, Tanaka S, Tanabe M. A novel classification of portal venous tumor invasion to predict residual tumor status after surgery in patients with pancreatic neuroendocrine neoplasms. J Cancer Res Clin Oncol. 2022.04; 148 (4): 931-941. ( PubMed, DOI )

  16. Asakawa, A; Kawade, G; Kurata, M; Fukuda, S; Onishi, I; Kinowaki, Y; Ishibashi, S; Ikeda, M; Watabe, S; Kobayashi, M; Ishibashi, H; Okubo, K; Kitagawa, M; Yamamoto, K. Stratification of lung squamous cell carcinoma based on ferroptosis regulators: Potential for new therapeutic strategies involving ferroptosis induction LUNG CANCER. 2022.03; 165 82-90. ( PubMed, DOI )

  17. Fukumura Y, Kinowaki Y, Matsuda Y, Takase M, Tonosaki M, Minagawa M, Saiura A, Tanabe M, Okano K, Suzuki Y, Kato K, Yao T. Intralobular distribution of ovarian-like stroma in pancreatic mucinous cystic neoplasms: a discussion on its tumorigenesis. Scientific reports. 2022.02; 12 (1): 3326. ( PubMed, DOI )

  18. Sekine Y, Yamamoto K, Kurata M, Honda A, Onishi I, Kinowaki Y, Kawade G, Watabe S, Nomura S, Fukuda S, Ishibashi S, Ikeda M, Yamamoto M, Kitagawa M. HADHB, a fatty acid beta-oxidation enzyme, is a potential prognostic predictor in malignant lymphoma. Pathology. 2021.09; 54 (3): 286-293. ( PubMed, DOI )

  19. Kinowaki Y, Taguchi T, Onishi I, Kirimura S, Kitagawa M, Yamamoto K. Overview of Ferroptosis and Synthetic Lethality Strategies. International journal of molecular sciences. 2021.08; 22 (17): ( PubMed, DOI )

  20. Kinowaki Y, Abe S, Abe S, Tomii S, Yukimori A, Akashi T, Tokunaga M, Kitagawa M. Synovial sarcoma of the stomach: a case report and a systematic review of literature. Clinical journal of gastroenterology. 2021.08; 14 (4): 1020-1026. ( PubMed, DOI )

  21. Kinowaki Yuko, Abe Shiho, Abe Shinya, Tomii Shohei, Yukimori Akane, Akashi Takumi, Tokunaga Masanori, Kitagawa Masanobu. 胃原発滑膜肉腫　症例報告とシステマティックレビュー(Synovial sarcoma of the stomach: a case report and a systematic review of literature) Clinical Journal of Gastroenterology. 2021.08; 14 (4): 1020-1026. ( ichushi )

  22. Ikeda Sadakatsu, Kudo Ryo, Yamashita Yamato, Noji Rika, Yokobori Jyunko, Ohki Mika, Takamine Eriko, Kobayashi Yumi, Egawa Makiko, Ebana Yusuke, Kimura Koichiro, Yokoyama Kohta, Onishi Iichiro, Takemoto Akira, Kirimura Susumu, Kinowaki Yuko, Tanimoto Kosuke, Miya Fuyuki, Kano Yoshihito, Yoshida Masayuki, Miyake Satoshi. Clinical utility of multi-disciplinary expert panel discussion in precision cancer medicine ANNALS OF ONCOLOGY. 2021.07; 32 S287. ( DOI )

  23. Maekawa A, Kudo A, Kishino M, Murase Y, Watanabe S, Ishikawa Y, Ueda H, Akahoshi K, Ogawa K, Ono H, Tanaka S, Kinowaki Y, Tanabe M.. Hormonal tumor mapping for liver metastases of gastroenteropancreatic neuroendocrine neoplasms: a novel therapeutic strategy Journal of Cancer Research and Clinical Oncology. 2021.04; published online

  24. Maekawa Aya, Kudo Atsushi, Kishino Mitsuhiro, Murase Yoshiki, Watanabe Shuichi, Ishikawa Yoshiya, Ueda Hiroki, Akahoshi Keiichi, Ogawa Kosuke, Ono Hiroaki, Tanaka Shinji, Kinowaki Yuko, Tanabe Minoru. Hormonal tumor mapping for liver metastases of gastroenteropancreatic neuroendocrine neoplasms: a novel therapeutic strategy JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. 2021.04; 148 (3): 697-706. ( PubMed, DOI )

  25. Taguchi T, Kurata M, Onishi I, Kinowaki Y, Sato Y, Shiono S, Ishibashi S, Ikeda M, Yamamoto M, Kitagawa M, Yamamoto K. SECISBP2 is a novel prognostic predictor that regulates selenoproteins in diffuse large B-cell lymphoma. Laboratory investigation; a journal of technical methods and pathology. 2021.02; 101 (2): 218-227. ( PubMed, DOI )

  26. Miura Keiko, Akashi Takumi, Namiki Takeshi, Hishima Tsunekazu, Bae Yuan, Sakurai Urara, Murano Keimei, Shiraishi Junichi, Warabi Masahiro, Tanizawa Toru, Tanaka Michio, Bhunchet Ekapot, Kumagai Jiro, Ayabe Shinya, Sekiya Takahiro, Ando Noboru, Shintaku Hiroshi, Kinowaki Yuko, Tomii Shohei, Kirimura Susumu, Kayamori Kou, Yamamoto Kurara, Ito Takashi, Eishi Yoshinobu. Engrailed Homeobox 1 and Cytokeratin 19 Are Independent Diagnostic Markers of Eccrine Porocarcinoma and Distinguish It From Squamous Cell Carcinoma AMERICAN JOURNAL OF CLINICAL PATHOLOGY. 2020.10; 154 (4): 499-509. ( PubMed, DOI )

  27. 田口 登和子, 山本 浩平, 木脇 祐子, 大西 威一郎, 倉田 盛人, 山本 正英, 北川 昌伸. びまん性大細胞性リンパ腫においてSECISBP2はセレノプロテインを調整する新規の予後予測因子になりうる 日本癌学会総会記事. 2020.10; 79回 PJ14-16. ( ichushi )

  28. Minami Y, Sato S, Koyanagi H, Kinowaki Y. Malignant primary pulmonary meningioma with bone metastasis. Oxford medical case reports. 2020.02; 2020 (2): omaa005. ( PubMed, DOI )

  29. Liu Bo, Kudo Atsushi, Kinowaki Yuko, Ogura Toshiro, Ogawa Kosuke, Ono Hiroaki, Mitsunori Yusuke, Ban Daisuke, Tanaka Shinji, Akashi Takumi, Tanabe Minoru. 高分化型膵神経内分泌腫瘍患者の予後を予測する簡便で実用的な指数(A simple and practical index predicting the prognoses of the patients with well-differentiated pancreatic neuroendocrine neoplasms) Journal of Gastroenterology. 2019.09; 54 (9): 819-828. ( ichushi )

  30. Liu Bo, Kudo Atsushi, Kinowaki Yuko, Ogura Toshiro, Ogawa Kosuke, Ono Hiroaki, Mitsunori Yusuke, Ban Daisuke, Tanaka Shinji, Akashi Takumi, Tanabe Minoru. A simple and practical index predicting the prognoses of the patients with well-differentiated pancreatic neuroendocrine neoplasms JOURNAL OF GASTROENTEROLOGY. 2019.09; 54 (9): 819-828. ( PubMed, DOI )

  31. Fukumura Yuki, Doi Reiko, Onagi Hiroko, Tonosaki Momoko, Ura Ayako, Saito Tsuyoshi, Kinowaki Yuko, Takase Masaru, Yao Takashi. Differences in histology, molecular features and cancer pathway between two types of intraductal papillary neoplasm of the bile duct MODERN PATHOLOGY. 2019.03; 32

  32. Fukumura Yuki, Doi Reiko, Onagi Hiroko, Tonosaki Momoko, Ura Ayako, Saito Tsuyoshi, Kinowaki Yuko, Takase Masaru, Yao Takashi. Differences in histology, molecular features and cancer pathway between two types of intraductal papillary neoplasm of the bile duct LABORATORY INVESTIGATION. 2019.03; 99

  33. Matsuda Yoko, Kinowaki Yuko, Fukumura Yuki, Aida Junko, Takubo Kaiyo, Ishiwata Toshiyuki, Arai Tomio. Acute Pancreatitis in Autopsies Associated with Surgeries and Severe Inflammatory Diseases LABORATORY INVESTIGATION. 2019.03; 99

  34. Matsuda Yoko, Kinowaki Yuko, Fukumura Yuki, Aida Junko, Takubo Kaiyo, Ishiwata Toshiyuki, Arai Tomio. Acute Pancreatitis in Autopsies Associated with Surgeries and Severe Inflammatory Diseases MODERN PATHOLOGY. 2019.03; 32

  35. Kinowaki Y., Matsuda Y., Fukumura Y., Kudo A., Akashi T., Kitagawa M.. Alternative Lengthening of Telomeres Predicts Metastatic Disease and Poor Survival in Patients With Pancreatic Neuroendocrine Tumors PANCREAS. 2019; 48 (10): 1462.

  36. Matsuda Yoko, Masuda Yoshishige, Shimoji Keigo, Matsukawa Miho, Kinowaki Yuko, Fukumura Yuki, Kikuyama Masataka, Arai Tomio. Severe Acute Pancreatitis in Autopsies Associated With Surgeries and Severe Inflammatory Diseases PANCREAS. 2019; 48 (10): 1321-1328. ( PubMed, DOI )

  37. Adachi Takuya, Yokoyama Minato, Fujii Yasuhisa, Kinowaki Yuko, Kirimura Susumu, Kubota Kazunori, Saida Yukihisa, Tateishi Ukihide. Neuroblastic tumors in young adults as a sequela of malignant neuroblastoma: report of two cases ABDOMINAL RADIOLOGY. 2018.07; 43 (7): 1531-1534. ( PubMed, DOI )

  38. Aihemaiti G, Kurata M, Nogawa D, Yamamoto A, Mineo T, Onishi I, Kinowaki Y, Jin XH, Tatsuzawa A, Miyasaka N, Kitagawa M, Yamamoto K. Subcellular localization of MCM2 correlates with the prognosis of ovarian clear cell carcinoma. Oncotarget. 2018.06; 9 (46): 28213-28225. ( PubMed, DOI )

  39. Yuko Kinowaki, Morito Kurata, Sachiko Ishibashi, Masumi Ikeda, Anna Tatsuzawa, Masahide Yamamoto, Osamu Miura, Masanobu Kitagawa, Kouhei Yamamoto. Glutathione peroxidase 4 overexpression inhibits ROS-induced cell death in diffuse large B-cell lymphoma Laboratory Investigation. 2018.02; ( PubMed, DOI )

  40. Kinowaki Yuko, Yamamoto Kohei, Kurata Morito, Onishi Iichiroh, Kitagawa Masanobu. Clinico-pathological analysis of GPX4 expression in Diffuse large B cell lymphoma CANCER SCIENCE. 2018.01; 109 683.

  41. Kinowaki Y., Matsuda Y.. Use of Periodic-acid Schiff and Alcian Blue (PAS-AB) Stains for Diagnosis of Pancreatic Cancer PANCREAS. 2018; 47 (10): 1400.

  42. 木脇 祐子, 山本 浩平, 倉田 盛人, 大西 威一郎, 北川 昌伸. びまん性大細胞型B細胞リンパ腫におけるGPX4の臨床病理学的検討 日本癌学会総会記事. 2017.09; 76回 P-2230. ( ichushi )

  43. 木脇 祐子, 山本 浩平, 倉田 盛人, 大西 威一郎, 北川 昌伸. びまん性大細胞リンパ腫におけるGPX4の臨床病理学的検討(Clinico-pathological analysis of GPX4 expression in diffuse large B cell lymphoma) 日本病理学会会誌. 2017.03; 106 (1): 464. ( ichushi )

  44. Yuko Kinowaki, Yutaka Takazawa, Noriko Yamamoto, Yuichi Ishikawa. Intraductal papillary mucinous neoplasm involving pancreaticobiliary maljunction and an aberrant pancreatic duct draining into the stomach: A case report and review of the literature Pathology - Research and Practice. 2016.02; 212 (2): 139-144. ( PubMed )

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Conference Activities & Talks 【 display / non-display 】

  1. 田村 一洋, 山本 浩平, 渡部 紫織, 川出 玄二, 大西 威一郎, 木脇 祐子, 石橋 佐知子, 池田 真住, 倉田 盛人, 大橋 健一. 肝細胞癌(HCC)における4-hydroxynonenal(4-HNE)の臨床病理学的および分子生物学的検討(Clinicopathological and molecular analysis of 4-hydroxynonenal(4-HNE) in Hepatocellular carcinoma). 日本病理学会会誌 2023.03.01

  2. Kinowaki Yuko, Fukumura Yuki, Matsuda Yoko, Akashi Takumi, Akahoshi Keiichi, Kobayashi Masanori, Ono Hiroaki, Kudo Atsushi, Tanabe Minoru, Kitagawa Masanobu. Pancreatic mixed neuroendocrine-non-neuroendocrine neoplasm: a case series of 6 patients(タイトル和訳中). 膵臓 2022.09.01

  3. Fukumura Yuki, Kinowaki Yuko, Matsuda Yoko, Takase Masaru, Maimaitiaili Yifare Maimaitiaili, Rong Lu, Akahoshi Keiichi, Tanabe Minoru, Okano Keiichi, Sano Katsuhiro, Saiura Akio, Kobayashi Masanori, Tomishima Ko, Fujisawa Toshio, Isayama Hiroyuki, Yao Takashi. Size- and age-related alterations of mucinous cystic neoplasm: a proposal on MCN progression(タイトル和訳中). 膵臓 2022.09.01

  4. Fukumura Yuki, Kinowaki Yuko, Matsuda Yoko, Takase Masaru, Maimaitiaili Yifare Maimaitiaili, Rong Lu, Akahoshi Keiichi, Tanabe Minoru, Okano Keiichi, Sano Katsuhiro, Saiura Akio, Kobayashi Masanori, Tomishima Ko, Fujisawa Toshio, Isayama Hiroyuki, Yao Takashi. 粘液性嚢胞腫瘍の大きさと年齢による変化　MCN進行に関する提案(Size- and age-related alterations of mucinous cystic neoplasm: a proposal on MCN progression). 膵臓 2022.09.01

  5. Kinowaki Yuko, Fukumura Yuki, Matsuda Yoko, Akashi Takumi, Akahoshi Keiichi, Kobayashi Masanori, Ono Hiroaki, Kudo Atsushi, Tanabe Minoru, Kitagawa Masanobu. 膵mixed neuroendocrine-non-neuroendocrine neoplasm　6例の症例シリーズ(Pancreatic mixed neuroendocrine-non-neuroendocrine neoplasm: a case series of 6 patients). 膵臓 2022.09.01

  6. Yuko Kinowaki. Use of periodic-acid Schiff and Alcian blue (PAS-AB) stains for diagnosis of pancreatic cancer.. the 49th Annual Meeting of the American Pancreatic Association 2018.11.01 Miami

  7. 木脇 祐子, 山本 浩平, 倉田 盛人, 大西 威一郎, 北川 昌伸. びまん性大細胞型B細胞リンパ腫におけるGPX4の臨床病理学的検討. 日本癌学会総会記事 2017.09.01

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