経歴(学内) 【 表示 ／ 非表示 】
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2017年07月-2018年03月東京医科歯科大学 （旧組織）医学部附属病院 診療科 内科系診療部門 血液内科 医員
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2018年04月-2022年03月東京医科歯科大学 大学院医歯学総合研究科 医歯学専攻 先端医療開発学講座 血液内科学分野 大学院生
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2022年04月-現在東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 全人的医療開発学講座 臨床腫瘍学 助教
論文・総説 【 表示 ／ 非表示 】
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Tanaka H, Yoshida S, Aoyama S, Ikeda S, Kunieda J, Ohashi K, Fukuda S, Waseda Y, Tanaka H, Fujii Y. A case of double-negative prostate cancer with BRCA2 mutation and high tumor mutation burden treated sequentially with olaparib and pembrolizumab. IJU case reports. 2024.09; 7 (5): 395-398. ( PubMed, DOI )
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Satoru Aoyama, Shunichiro Yasuda, Huixin Li, Daisuke Watanabe, Yoshihiro Umezawa, Keigo Okada, Ayako Nogami, Osamu Miura, Norihiko Kawamata. A novel chimeric antigen receptor (CAR) system using an exogenous protease, in which activation of T cells is controlled by expression patterns of cell‑surface proteins on target cells. International Journal of Molecular Medicine. 2022.04; 49 (4): ( PubMed, DOI )
講演・口頭発表等 【 表示 ／ 非表示 】
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Satoru Aoyama. TWIN-HEAD CAR-T™ CAR-T cell therapy for Solid Tumors without Fatal Side Effects. Stanford SPARK global meeting 2024.09.17
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本村 鷹多朗, 吉藤 康太, 貞任 大地, 野上 彩子, 齊藤 真貴子, 岡田 啓五, 青山 慧, 森 毅彦, 長尾 俊景. 新規GCB-DLBCL細胞株TMD13の樹立と特性評価(Establishment and characterization of TMD13. a novel GCB-type DLBCL cell line). 日本リンパ網内系学会会誌 2023.06.01
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Satoru Aoyama, Takashi Kamatani, Kousuke Tanimoto, Junko Yokobori, Eriko Takamine, Makiko Egawa, Yuki Kato, Susumu Kirimura, Ichiro Ohnishi, Kouichiro Kimura, Takahiro Asakage, Sadakatsu Ikeda. Case report: Myxofibrosarcoma in the head and neck region with rare TP53 aberration in the background of retinoblastoma.. 2023 the Japanese Society of Medical Oncology Annual Meeting 2023.03.17
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Haruko Nakagawa, Satoru Aoyama, Junko Yokobori, Haruhiko Furusawa, Takahiro Mitsumura, Akira Takemoto, Ken Yamagiwa, Masaaki Kawanishi, Sadakatsu Ikeda. A novel Fumarate Hydratase mutation in a patient with lung adenocarcinoma: a case report. 2023 the Japanese Society of Medical Oncology Annual Meeting 2023.03.16
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Satoru Aoyama, Ayako Nogami, Sadakatsu Ikeda, Takehiko Mori. Novel protease-mediated double antigen recognizing Chimeric Antigen Receptor (CAR) enhances the directionality of CAR-T cell activity and improves target cell specificity.. Keystone symposia A4: Emerging Cellular Therapies at the Forefront of Cancer Immunotherapy 2023.01.31
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Satoru Aoyama, Ayako Nogami, Sadakatsu Ikeda, Takehiko Mori. Novel protease-mediated double antigen recognizing Chimeric Antigen Receptor (CAR) enhances directionality of CAR-T cell activity and improves target cell specificity.. 64th American Society of Hematology (ASH) annual Meeting and Exposition 2022.12.10
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Satoru Aoyama, Shunichiro Yasuda, Huixin Li, Daisuke Watanabe, Hiroki Akiyama, Keigo Okada, Yoshihiro Umezawa, Ayako Nogami, Osamu Miura, Norihiko Kawamata. Protease mediated Regulatory Chimeric Antigen Receptor (CAR) Improves Target Specificity.. The 83rd Annual Meeting of the Japanese Society of Hematology 2021.09.24
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Satoru Aoyama,Shunichiro Yasuda,Daisuke Watanabe,Hiroki Akiyama,Keigo Okada,Yoshihiro Umezawa,Ayako Nogami,Osamu Miura,Norihiko Kawamata. A Protease-Mediated Regulatory Chimeric Antigen Receptor (CAR): “Double Arm” CAR System Improves Tumor-cell-Specificity of CAR-T Cell Therapy.. 62nd American Society of Hematology (ASH) annual Meeting and Exposition 2020.12.06 virtual meeting
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Satoru Aoyama,Shunichiro Yasuda,Daisuke Watanabe,Hiroki Akiyama,Keigo Okada,Yoshihiro Umezawa,Ayako Nogami,Osamu Miura,Norihiko Kawamata. Protease harboring Chimeric Antigen Receptor (CAR) Regulates CAR-T Cell Activity. The 82nd Annual Meeting of the Japanese Society of Hematology 2020.10.10
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Satoru Aoyama,Shunichiro Yasuda,Daisuke Watanabe,Hiroki Akiyama,Keigo Okada,Yoshihiro Umezawa,Ayako Nogami,Osamu Miura,Norihiko Kawamata. A Protease-Mediated Regulatory Chimeric Antigen Receptor (CAR): “Scissors” CAR Improves Target Specificity through Regulation of CAR-T Cell Activity. American Association for Cancer Research (AACR) annual meeting 2020 2020.06.22
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Satoru Aoyama, Shunichiro Yasuda, Daisuke Watanabe, Yoshihiro Umezawa, Osamu Miura, Norihiko Kawamata. A multi-antigen recognition system for CAR-T technology using a protein cleavage method.. The 81st Annual Meeting of the Japanese Society of Hematology 2019.10.12 Tokyo, Japan
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Satoru Aoyama, Shunichiro Yasuda, Daisuke Watanabe, Yoshihiro Umezawa, Osamu Miura, Norihiko Kawamata. A Multi-antigen Recognition CAR-T Cell System Using Protease Mediated Protein Cleavage.. The 10th JSH International Symposium 2019.05.17 Mie, Japan
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青山 慧, 加納 嘉人, 末永 光邦, 池田 貞勝, 佐藤 信吾, 森 毅彦. 腫瘍内科専門医の育成に関する、新専門医制度を見据えた本学の取り組み. 第21回日本臨床腫瘍学会学術集会 2024.02.23
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野上 彩子、青山 慧、北浦 萌、山本 正英、東田 修二. CAR-T細胞療法後の遷延性血球減少症における免疫学的機構の解明. 第70回日本臨床検査医学会学術集会 2023.11.16 長崎
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岡田啓五、齋藤真貴子、本村鷹多朗、吉藤康太、青山慧、長尾俊景、野上彩子. FLT3-ITDはPDK1を活性化し、RskのN末端リン酸化とBimの阻害によりAML細胞の生存を強化する. 第85回日本血液学会学術集会 2023.10.13 東京
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Satoru Aoyama, Ayako Nogami, Sadakatsu Ikeda, Takehiko Mori. Establishment of novel Chimeric Antigen Receptor (CAR) improving the target-cell-specificity.. The 85th Annual Meeting of the Japanese Society of Hematology 2023.10.13
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Satoru Aoyama, Shunichiro Yasuda, Daisuke Watanabe, Hiroki Akiyama, Yoshihiro Umezawa, Ayako Nogami, Osamu Miura, Norihiko Kawamata. A Novel Protease-Mediated Chimeric Antigen Receptor (CAR): “Double-Arm” CAR-T cell system Improves Target Specificity of CAR-T Cell Therapy. The 61st ASH Annual Meeting and Exposition 2019.12.07 Orlando, FL
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青山 慧,堤 大樹,齊藤 達也,山本 正英,渡邉 健,長尾 俊景,福田 哲也,川又 紀彦,三浦 修. FLU/BU4/TBIを用いた前処置による骨髄系腫瘍に対する同種移植成績. 第40回日本造血細胞移植学会総会 2018.02.02 札幌