論文・総説 - 田中　敏博

141. Kitahara O, Furukawa Y, Tanaka T, Kihara C, Ono K, Yanagawa R, Nita ME, Takagi T, Nakamura Y, Tsunoda T. Alterations of gene expression during colorectal carcinogenesis revealed by cDNA microarrays after laser-capture microdissection of tumor tissues and normal epithelia. Cancer Res. 2001.05; 61 (9): 3544-3549. ( PubMed )

142. Suzuki Y, Taira H, Tsunoda T, Mizushima-Sugano J, Sese J, Hata H, Ota T, Isogai T, Tanaka T, Morishita S, Okubo K, Sakaki Y, Nakamura Y, Suyama A, Sugano S. Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites. EMBO Rep. 2001.05; 2 (5): 388-393. ( PubMed, DOI )

143. Suzuki Y, Tsunoda T, Sese J, Taira H, Mizushima-Sugano J, Hata H, Ota T, Isogai T, Tanaka T, Nakamura Y, Suyama A, Sakaki Y, Morishita S, Okubo K, Sugano S. Identification and characterization of the potential promoter regions of 1031 kinds of human genes. Genome Res. 2001.05; 11 (5): 677-684. ( PubMed, DOI )

144. Yamada R, Tanaka T, Unoki M, Nagai T, Sawada T, Ohnishi Y, Tsunoda T, Yukioka M, Maeda A, Suzuki K, Tateishi H, Ochi T, Nakamura Y, Yamamoto K. Association between a single-nucleotide polymorphism in the promoter of the human interleukin-3 gene and rheumatoid arthritis in Japanese patients, and maximum-likelihood estimation of combinatorial effect that two genetic loci have on susceptibility to the disease. Am J Hum Genet. 2001.03; 68 (3): 674-685. ( PubMed, DOI )

145. Kunishima S, Kojima T, Matsushita T, Tanaka T, Tsurusawa M, Furukawa Y, Nakamura Y, Okamura T, Amemiya N, Nakayama T, Kamiya T, Saito H. Mutations in the NMMHC-A gene cause autosomal dominant macrothrombocytopenia with leukocyte inclusions (May-Hegglin anomaly/Sebastian syndrome). Blood. 2001.02; 97 (4): 1147-1149. ( PubMed )

146. Kato T, Satoh S, Okabe H, Kitahara O, Ono K, Kihara C, Tanaka T, Tsunoda T, Yamaoka Y, Nakamura Y, Furukawa Y. Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis. Neoplasia. 2001.01; 3 (1): 4-9. ( PubMed, DOI )

147. Iwasa H, Kurabayashi M, Nagai R, Nakamura Y, Tanaka T. Multiple single-nucleotide polymorphisms (SNPs) in the Japanese population in six candidate genes for long QT syndrome. J Hum Genet. 2001; 46 (3): 158-162. ( PubMed, DOI )

148. Itoh T, Kikuchi K, Odagawa Y, Takata S, Yano K, Okada S, Haneda N, Ogawa S, Nakano O, Kawahara Y, Kasai H, Nakayama T, Fukutomi T, Sakurada H, Shimizu A, Yazaki Y, Nagai R, Nakamura Y, Tanaka T. Correlation of genetic etiology with response to beta-adrenergic blockade among symptomatic patients with familial long-QT syndrome. J Hum Genet. 2001; 46 (1): 38-40. ( PubMed, DOI )

149. Iida A, Ohnishi Y, Ozaki K, Ariji Y, Nakamura Y, Tanaka T. High-density single-nucleotide polymorphism (SNP) map in the 96-kb region containing the entire human DiGeorge syndrome critical region 2 (DGCR2) gene at 22q11.2. J Hum Genet. 2001; 46 (10): 604-608. ( PubMed, DOI )

150. Iwasa H, Kurabayashi M, Nagai R, Nakamura Y, Tanaka T. Genetic variations in five genes involved in the excitement of cardiomyocytes. J Hum Genet. 2001; 46 (9): 549-552. ( PubMed, DOI )

151. Ohnishi Y, Tanaka T, Ozaki K, Yamada R, Suzuki H, Nakamura Y. A high-throughput SNP typing system for genome-wide association studies. J Hum Genet. 2001; 46 (8): 471-477. ( PubMed, DOI )

152. Nakajima T, Kurabayashi M, Ohyama Y, Kaneko Y, Furukawa T, Itoh T, Taniguchi Y, Tanaka T, Nakamura Y, Hiraoka M, Nagai R. Characterization of S818L mutation in HERG C-terminus in LQT2. Modification of activation-deactivation gating properties. FEBS Lett. 2000.09; 481 (2): 197-203. ( PubMed )

153. Ono K, Tanaka T, Tsunoda T, Kitahara O, Kihara C, Okamoto A, Ochiai K, Takagi T, Nakamura Y. Identification by cDNA microarray of genes involved in ovarian carcinogenesis. Cancer Res. 2000.09; 60 (18): 5007-5011. ( PubMed )

154. Yamauchi T, Tada M, Houkin K, Tanaka T, Nakamura Y, Kuroda S, Abe H, Inoue T, Ikezaki K, Matsushima T, Fukui M. Linkage of familial moyamoya disease (spontaneous occlusion of the circle of Willis) to chromosome 17q25. Stroke. 2000.04; 31 (4): 930-935. ( PubMed )

155. Ohnishi Y, Tanaka T, Yamada R, Suematsu K, Minami M, Fujii K, Hoki N, Kodama K, Nagata S, Hayashi T, Kinoshita N, Sato H, Sato H, Kuzuya T, Takeda H, Hori M, Nakamura Y. Identification of 187 single nucleotide polymorphisms (SNPs) among 41 candidate genes for ischemic heart disease in the Japanese population. Hum Genet. 2000.03; 106 (3): 288-292. ( PubMed )

156. Yamada R, Tanaka T, Ohnishi Y, Suematsu K, Minami M, Seki T, Yukioka M, Maeda A, Murata N, Saiki O, Teshima R, Kudo O, Ishikawa K, Ueyosi A, Tateishi H, Inaba M, Goto H, Nishizawa Y, Tohma S, Ochi T, Yamamoto K, Nakamura Y. Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population. Hum Genet. 2000.03; 106 (3): 293-297. ( PubMed )

157. Iwasa H, Itoh T, Nagai R, Nakamura Y, Tanaka T. Twenty single nucleotide polymorphisms (SNPs) and their allelic frequencies in four genes that are responsible for familial long QT syndrome in the Japanese population. J Hum Genet. 2000; 45 (3): 182-183. ( PubMed, DOI )

158. Seki T, Tanaka T, Nakamura Y. Genomic structure and multiple single-nucleotide polymorphisms (SNPs) of the thiopurine S-methyltransferase (TPMT) gene. J Hum Genet. 2000; 45 (5): 299-302. ( PubMed, DOI )

159. Tsunoda T, Yamada R, Tanaka T, Ohnishi Y, Kamatani N. Environmental factor dependent maximum likelihood method for association study targeted to personalized medicine. Genome Inform Ser Workshop Genome Inform. 2000; 11 96-105. ( PubMed )

160. Kunishima S, Kojima T, Tanaka T, Kamiya T, Ozawa K, Nakamura Y, Saito H. Mapping of a gene for May-Hegglin anomaly to chromosome 22q. Hum Genet. 1999.11; 105 (5): 379-383. ( PubMed )