Published Papers & Misc - TSUJI Kunikazu

1. Riko Yamashita, Iori Nozawa, Shoichi Hasegawa, Yusuke Nakagawa, Kazumasa Miyatake, Hiroki Katagiri, Tomomasa Nakamura, Hideyuki Koga, Ichiro Sekiya, Toshitaka Yoshii, Kunikazu Tsuji. C-type natriuretic peptide suppresses VEGFa gene expression by attenuating IL6-STAT3 signal pathway in primary synovial fibroblasts from rat knee. Biochem Biophys Res Commun. 2025.02; 749 151290. ( PubMed, DOI )

2. Shoichi Hasegawa, Riko Yamashita, Yusuke Nakagawa, Kazumasa Miyatake, Hiroki Katagiri, Tomomasa Nakamura, Hideyuki Koga, Ichiro Sekiya, Toshitaka Yoshii, Vicki Rosen, Kunikazu Tsuji. A novel methodology utilizing microchip implants to monitor individual activity and body temperature for assessing knee pain in group-housed rats. Sci Rep. 2024.07; 14 (1): 16909. ( PubMed, DOI )

3. Ryu Yoshida, Hideyuki Koga, Junpei Matsuda, Tomomasa Nakamura, Kazumasa Miyatake, Hiroki Katagiri, Mai Katakura, Aritoshi Yoshihara, Ryota Seki, Toyohiro Katsumata, Mitsuru Mizuno, Ken Watanabe, Ichiro Sekiya, Kunikazu Tsuji, Yusuke Nakagawa. Presoaking Grafts in Vancomycin Does Not Impair Graft-Bone Healing in a Rat Anterior Cruciate Ligament Reconstruction Model. Am J Sports Med. 2024.06; 52 (7): 1784-1793. ( PubMed, DOI )

4. Yang Yang, Hideyuki Koga, Yusuke Nakagawa, Tomomasa Nakamura, Hiroki Katagiri, Ryohei Takada, Mai Katakura, Kunikazu Tsuji, Ichiro Sekiya, Kazumasa Miyatake. Characteristics of the synovial microenvironment and synovial mesenchymal stem cells with hip osteoarthritis of different bone morphologies. Arthritis Res Ther. 2024.01; 26 (1): 17.

5. Zhen Qu, Hideyuki Koga, Kunikazu Tsuji, Guo Tang, Yang Yang, Aritoshi Yoshihara, Mai Katakura, Hiroki Katagiri, Kazumasa Miyatake, Tomomasa Nakamura, Ichiro Sekiya, Yusuke Nakagawa. Hyaluronic acid sheet transplantation attenuates infrapatellar fat pad fibrosis and pain in a rat arthritis model. J Orthop Res. 2023.11; 41 (11): 2442-2454. ( PubMed, DOI )

6. Zhu Ling, Hailati Aini, Shuhei Kajikawa, Jumpei Shirakawa, Kunikazu Tsuji, Yoshinori Asou, Hideyuki Koga, Ichiro Sekiya, Akira Nifuji, Masaki Noda, Yoichi Ezura. Mutation Are Treatable by Alendronate. Pharmaceuticals (Basel). 2023.10; 16 (10): ( PubMed, DOI )

7. Shoichi Hasegawa, Jae-Sung An, Jun Hino, Yusuke Amano, Yusuke Nakagawa, Kazumasa Miyatake, Hiroki Katagiri, Tomomasa Nakamura, Ichiro Sekiya, Hideyuki Koga, Kunikazu Tsuji. Therapeutic effect of C-type natriuretic peptide on persistent pain in a rat knee arthritis model. J Orthop Surg (Hong Kong). 2023.06; 31 (2): 10225536231181708. ( PubMed, DOI )

8. Yusuke Nakagawa, Kunikazu Tsuji, Tomomasa Nakamura, Hiroki Katagiri, Nobutake Ozeki, Mikio Shioda, Jae-Sung An, Ryu Yoshida, Ichiro Sekiya, Hideyuki Koga. Association of Infrapatellar Fat Pad Fibrosis at 3 Months After ACL Reconstruction With Short-term Clinical Outcomes and Inflammatory Cytokine Levels in the Synovial Fluid. Orthop J Sports Med. 2023.04; 11 (4): 23259671231164122. ( PubMed, DOI )

9. Takanori Wakayama, Yoshitomo Saita, Masashi Nagao, Sayuri Uchino, Sei-Ichi Yoshihara, Kunikazu Tsuji, Hideyuki Koga, Yohei Kobayashi, Hirofumi Nishio, Yasumasa Momoi, Hiroshi Ikeda, Kazuo Kaneko, Muneaki Ishijima. Intra-Articular Injections of the Adipose-Derived Mesenchymal Stem Cells Suppress Progression of a Mouse Traumatic Knee Osteoarthritis Model. Cartilage. 2022.12; 13 (4): 148-156. ( PubMed, DOI )

10. Shunichi Fujii, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya. Comparison of adhesion of thawed and cultured synovial mesenchymal stem cells to the porcine meniscus and the relevance of cell surface microspike BMC Molecular and Cell Biology. 2022.12; 23 (1): 53. ( PubMed, DOI )

11. Masaaki Isono, Jun Takeuchi, Ami Maehara, Yusuke Nakagawa, Hiroki Katagiri, Kazumasa Miyatake, Ichiro Sekiya, Hideyuki Koga, Yoshinori Asou, Kunikazu Tsuji. Effect of CD44 signal axis in the gain of mesenchymal stem cell surface antigens from synovial fibroblasts in vitro Heliyon. 2022.10; 8 (10): e10739. ( PubMed, DOI )

12. Guo Tang, Yoshinori Asou, Etsuko Matsumura, Yusuke Nakagawa, Kazumasa Miyatake, Hiroki Katagiri, Tomomasa Nakamura, Hideyuki Koga, Keiichiro Komori, Ichiro Sekiya, Yoich Ezura, Kunikazu Tsuji. Short cytoplasmic isoform of IL1R1/CD121a mediates IL1β induced proliferation of synovium-derived mesenchymal stem/stromal cells through ERK1/2 pathway. Heliyon. 2022.05; 8 (5): e09476. ( PubMed, DOI )

13. Hiroki Katagiri, Kaori Nakamura, Takeshi Muneta, Toshifumi Watanabe, Kazumasa Miyatake, Ichiro Sekiya, Hideyuki Koga, Kunikazu Tsuji. Inflammatory and healing environment in synovial fluid after anterior cruciate ligament reconstruction: Granulocytes and endogenous opioids as new targets of postoperative pain. Biochem Biophys Rep. 2021.07; 26 100981. ( PubMed, DOI )

14. Hiroko Ueki, Hiroki Katagiri, Kunikazu Tsuji, Kazumasa Miyatake, Toshifumi Watanabe, Ichiro Sekiya, Takeshi Muneta, Hideyuki Koga. Effect of transplanted mesenchymal stem cell number on the prevention of cartilage degeneration and pain reduction in a posttraumatic osteoarthritis rat model. J Orthop Sci. 2021.07; 26 (4): 690-697. ( PubMed, DOI )

15. Kazumasa Kawata, Hideyuki Koga, Kunikazu Tsuji, Kazumasa Miyatake, Yusuke Nakagawa, Takanori Yokota, Ichiro Sekiya, Hiroki Katagiri. Extracellular vesicles derived from mesenchymal stromal cells mediate endogenous cell growth and migration via the CXCL5 and CXCL6/CXCR2 axes and repair menisci. Stem Cell Res Ther. 2021.07; 12 (1): 414. ( PubMed, DOI )

16. Kiyotaka Horiuchi, Nobutake Ozeki, Kentaro Endo, Mitsuru Mizuno, Hisako Katano, Masako Akiyama, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya. Thawed cryopreserved synovial mesenchymal stem cells show comparable effects to cultured cells in the inhibition of osteoarthritis progression in rats. Sci Rep. 2021.05; 11 (1): 9683. ( PubMed, DOI )

17. Horiuchi Kiyotaka, Mizuno Mitsuru, Katano Hisako, Endo Kentaro, Ozeki Nobutake, Tsuji Kunikazu, Koga Hideyuki, Sekiya Ichiro.. Optimal initial cell density that yields the highest number of primary synovial mesenchymal stem cells in a clinical setting. J Med Dent Sci.. 2021.04; 68 17-26.

18. J-S An, K Tsuji, H Onuma, N Araya, M Isono, T Hoshino, K Inomata, J Hino, M Miyazato, H Hosoda, K Kangawa, Y Nakagawa, H Katagiri, K Miyatake, I Sekiya, T Muneta, H Koga. Inhibition of fibrotic changes in infrapatellar fat pad alleviates persistent pain and articular cartilage degeneration in monoiodoacetic acid-induced rat arthritis model. Osteoarthritis Cartilage. 2021.03; 29 (3): 380-388. ( PubMed, DOI )

19. Aidehamu Aihemaiti, Naoki Yamamoto, Jinying Piao, Takuya Oyaizu, Hiroki Ochi, Shingo Sato, Atsushi Okawa, Toshio Miyata, Kunikazu Tsuji, Yoichi Ezura, Yoshinori Asou. A novel PAI-1 inhibitor prevents ageing-related muscle fiber atrophy. Biochem Biophys Res Commun. 2021.01; 534 849-856. ( PubMed, DOI )

20. Yoshihisa Kushida, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Kunikazu Tsuji, Hideyuki Koga, Koichiro Kishima, Yoshio Soma, Ichiro Sekiya. Two- and three-dimensional optical coherence tomography to differentiate degenerative changes in a rat meniscectomy model. J Orthop Res. 2020.12; 38 (12): 2592-2600. ( PubMed, DOI )