Personnel Information


YUI Nobuhiko

Job title


Birth date


Mail Address

The inquiry by e-mail is 《here

Graduating School 【 display / non-display

  • Sophia University, Faculty of Science and Engineering, 1981, Graduated

Graduate School 【 display / non-display

  • Sophia University, Graduate School, Division of Science and Engineering, Doctor's Course, 1985, Completed

Degree 【 display / non-display

  • Ph. D., Sophia University

Campus Career 【 display / non-display

  • 2016.04
    Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Biomedical Materials, Organic Biomaterials, Professor
  • 2011.01
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Oral Health Sciences, Organic Biomaterials, Professor

External Career 【 display / non-display

  • 2011.01
    , Professor
  • 1998
    , Professor

Academic Society Affiliations 【 display / non-display

  • Japanese Society for Biomaterials

  • Japan Society of Drug Delivery System

  • Japanese Society for Dental Materials and Devices

Academic Activity 【 display / non-display

  • 2018.04
    Japanese Society for Biomaterials President
  • Japanese Society for Biomaterials Board of Director
  • Japanese Society for Dental Materials and Devices Board of Director
  • Japan Society of Drug Delivery System Board Member

Research Areas 【 display / non-display

  • Biomedical engineering/Biomaterial science and engineering

  • Functional solid state chemistry

  • Nanomaterials chemistry


Published Papers & Misc 【 display / non-display

  • Yoshinori Arisaka, Asato Tonegawa, Atsushi Tamura, Nobuhiko Yui. Terminally cross-linking polyrotaxane hydrogels applicable for cellular microenvironments Journal of Applied Polymer Science. 2021.01; 138 (3): 49706. ( DOI )

  • Masahiko Terauchi, Atsushi Tamura, Yoshinori Arisaka, Hiroki Masuda, Tetsuya Yoda, Nobuhiko Yui. Cyclodextrin-based supramolecular complexes of osteoinductive agents for dental tissue regeneration Pharmaceutics. 2021.01; 13 (2): 136. ( DOI )

  • Yoshinori Arisaka, Masahiro Hakariya, Takanori Iwata, Hiroki Masuda, Tetsuya Yoda, Atsushi Tamura, Nobuhiko Yui. Surface-tethering of methylated polyrotaxanes with 4-vinylbenzyl groups onto poly(ether ether ketone) substrates for improving osteoblast compatibility. Dental Materials Journal. 2021;

  • Atsushi Tamura, Moe Ohashi, Asato Tonegawa, Tae Woong Kang, Shunyao Zhang, Nobuhiko Yui. Effect of alkyl chain length of acylated α-cyclodextrin-threaded polyrotaxanes on thermoresponsive phase transition behavior. Macromolecular Chemistry and Physics. 2021; 222

  • Ruriko Sekiya-Aoyama, Yoshinori Arisaka, Masahiro Hakariya, Hiroki Masuda, Takanori Iwata, Tetsuya Yoda, Nobuhiko Yui. Dual effect of molecular mobility and functional groups of polyrotaxane surfaces on the fate of mesenchymal stem cells Biomaterials Science. 2021; in press

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Books etc 【 display / non-display

  • Ji-Hun Seo, Nobuhiko Yui. "Functional Hydrogels as Biomaterials (Springer Series in Biomaterials Science and Engineering, vol 12)" Mobile properties of supramolecular polyrotaxane surfaces on modulation of cellular functions. Springer (Berlin, Heidelberg), 2018.07 Chapter 6. Mobile properties of supramolecular polyrotaxane surfaces on modulation of cellular functions (ISBN : 978-3662575093)

  • Nobuhiko Yui. "Supramolecular Polymer Chemistry" Emerging biomedical functions through “mobile” polyrotaxanes. Wiley-VCH, 2012.01 Part three Properties and Functions 9. Emerging biomedical functions through “mobile” polyrotaxanes (ISBN : 978-3527323210)

  • Nobuhiko Yui, Kazuhiko Ishihara, Akio Kishida, Tetsuji Yamaoka. Nanobio-Interfaces in Relation to Molecular Mobility. JAIST Press, 2010.02 (ISBN : 978-4-903092-24-9)

  • Atsushi Yamashita, Nobuhiko Yui. "Biomaterials in Asia: In Commemoration of the 1st Asian Biomaterials Congress" Design of supramolecular polyrotaxanes for DNA delivery. World Scientific Publishing, 2009.01 PART Ⅵ. Drug Delivery System, 27.Design of supramolecular polyrotaxanes for DNA delivery (ISBN : 978-9812835741)

  • Tooru Ooya, Nobuhiko Yui. "Microspheres, Microcapsules and Liposomes: Smart Nano and Microparticles v.7 (Microspheres, microcapsules & liposomes)" Biofunctional polyrotaxanes for supramolecular enhanced recognition. Kentus Book, 2006.05 Biofunctional polyrotaxanes for supramolecular enhanced recognition (ISBN : 978-0953218776)

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Conference Activities & Talks 【 display / non-display

  • Supramolecule-based surfaces with intermediate mobility promote myocyte differentiation. 2020.05.29

  • Tae Woong Kang, Atsushi Tamura, Yoshinori Arisaka, Nobuhiko Yui. Preparation and characterization of novel functionalized polyrotaxanes capped by bulky trithiocarbonate goups. 第69回高分子学会年次大会 2020.05.29 福岡国際会議場, 福岡県福岡市

  • Zhang Shunyao, 田村篤志, 由井伸彦. pH応答型アニオン性ポリロタキサンの調製と細胞内在化効率の評価. 第69回高分子学会年次大会 2020.05.29 福岡国際会議場, 福岡県福岡市

  • Yoshinori Arisaka, Nobuhiko Yui. The effect of sulfonated polyrotaxane-surfaces on hepatic responses. International Symposium on Creation of Life Innovation Materials for Interdisciplinary and International Researcher Development Satellite (iLIM-s) 2019.11.02 Nagoya University, Nagoya, Japan

  • Dae Hoon Lee, Yoshinori Arisaka, Atsushi Tamura, Nobuhiko Yui. Improving mechanical properties of gelatin by polyrotaxane crosslinkers. Tissue Engineering & Regenerative Medicine International Society - AP Chapter and the 7th Asian Biomaterials Congress (TERMIS-AP + ABMC7 2019) 2019.10.17 Brisbane Convention & Exhibition Center, Brisbane, Australia

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Patents 【 display / non-display


    Patent Number: 10406243

Awards & Honors 【 display / non-display

  • FBSE Award,2008

  • 1996 CRS-Cygnus Recognition Award for Excellence in Guiding Student Research,1997

  • Award for Outstanding Research (Ph. D. Category),1985