Personnel Information

写真a

KOKAI Satoshi


Job title

Visiting Lecturer

Mail Address

The inquiry by e-mail is 《here》
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Graduating School 【 display / non-display 】

  • Tokyo Medical and Dental University, Faculty of Dentistry, 2002, Graduated

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Graduate School 【 display / non-display 】

  • Tokyo Medical and Dental University, Doctor's Course, 2006, Completed

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Campus Career 【 display / non-display 】

  • 2011.04
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    2018.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Oral Health Sciences， Orthodontic Science， Assistant Professor
  • 2006.04
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    2020.03
    Tokyo Medical and Dental University， (Old Organization)Dental Hospital， Hospital Departments， Clinics for Dentofacial Growth and Development， Orthodontics， Dental Resident
  • 2017.04
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Oral Health Sciences， Orthodontic Science， Visiting Lecturer
  • 2017.05
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    2018.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Oral Health Sciences， Orthodontic Science， Visiting Lecturer
  • 2018.05
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    2019.04
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Oral Health Sciences， Department of Orthodontic Science， Visiting Lecturer
  • 2019.05
    -
    2020.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Oral Health Sciences， Department of Orthodontic Science， Visiting Lecturer
  • 2020.05
    -
    2021.04
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Oral Health Sciences， Department of Orthodontic Science， Visiting Lecturer
  • 2021.05
    -
    2022.04
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Oral Health Sciences， Department of Orthodontic Science， Visiting Lecturer
  • 2022.05
    -
    2023.04
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Oral Health Sciences， Department of Orthodontic Science， Visiting Lecturer
  • 2023.05
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Oral Health Sciences， Department of Orthodontic Science， Visiting Lecturer

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Academic Society Affiliations 【 display / non-display 】

  • Charles H. Tweed Foundation for Orthodontic Research

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Research Areas 【 display / non-display 】

  • Developmental dentistry

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Qualification Acquired 【 display / non-display 】

  • Charles H. Tweed Foundation for Orthodontic Research, Fellowship member

  • Dentist

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Published Papers & Misc 【 display / non-display 】

  1. Eri Misawa-Omori, Hidemasa Okihara, Takuya Ogawa, Yasunori Abe, Chiho Kato, Hideyuki Ishidori, Akiyo Fujita, Satoshi Kokai, Takashi Ono. Reduced mastication during growth inhibits cognitive function by affecting trigeminal ganglia and modulating Wnt signaling pathway and ARHGAP33 molecular transmission Neuropeptides. 2023.08; ( DOI )

  2. Li Ruixin, Kato Chiho, Fujita Akiyo, Abe Yasunori, Ogawa Takuya, Ishidori Hideyuki, Misawa Eri, Okihara Hidemasa, Kokai Satoshi, Ono Takashi. Effect of Obesity on Masticatory Muscle Activity and Rhythmic Jaw Movements Evoked by Electrical Stimulation of Different Cortical Masticatory Areas JOURNAL OF CLINICAL MEDICINE. 2023.06; 12 (11): ( PubMed, DOI )

  3. Koecklin Karin Harumi Uchima, Kato Chiho, Abe Yasunori, Yabushita Tadachika, Kokai Satoshi, Ono Takashi. Histological and contractile changes in the genioglossus muscle after nasal obstruction in growing rats SCIENTIFIC REPORTS. 2023.04; 13 (1): 6245. ( PubMed, DOI )

  4. Fujita Akiyo, Kato Chiho, Abe Yasunori, Ishidori Hideyuki, Li Ruixin, Aung Phyo Thura, Ogawa Takuya, Okihara Hidemasa, Kokai Satoshi, Ono Takashi. Unilateral nasal obstruction affects development of cortical orofacial motor representation in the cortical masticatory area of growing rats NEUROSCIENCE LETTERS. 2022.07; 783 136700. ( PubMed, DOI )

  5. Aung Phyo Thura, Kato Chiho, Fujita Akiyo, Abe Yasunori, Ogawa Takuya, Ishidori Hideyuki, Okihara Hidemasa, Kokai Satoshi, Ono Takashi. Effects of low occlusal loading on the neuromuscular behavioral development of cortically-elicited jaw movements in growing rats SCIENTIFIC REPORTS. 2021.03; 11 (1): 7175. ( PubMed, DOI )

  6. Satokawa C, Nishiyama A, Suzuki K, Uesugi S, Kokai S, Ono T. Evaluation of tissue oxygen saturation of the masseter muscle during standardised teeth clenching. Journal of oral rehabilitation. 2020.01; 47 (1): 19-26. ( PubMed, DOI )

  7. Aung Phyo Thura, Kato Chiho, Abe Yasunori, Ogawa Takuya, Ishidori Hideyuki, Fujita Akiyo, Okihara Hidemasa, Kokai Satoshi, Ono Takashi. Functional Analysis of Rhythmic Jaw Movements Evoked by Electrical Stimulation of the Cortical Masticatory Area During Low Occlusal Loading in Growing Rats FRONTIERS IN PHYSIOLOGY. 2020.01; 11 34. ( PubMed, DOI )

  8. Kokai Satoshi, Fukuyama Eiji, Omura Susumu, Kimizuka Sachiko, Yonemitsu Ikuo, Fujita Koichi, Ono Takashi. Long-term stability after multidisciplinary treatment involving maxillary distraction osteogenesis, and sagittal split ramus osteotomy for unilateral cleft lip and palate with severe occlusal collapse and gingival recession: A case report KOREAN JOURNAL OF ORTHODONTICS. 2019.01; 49 (1): 59-69. ( PubMed, DOI )

  9. Ogawa Takuya, Okihara Hidemasa, Kokai Satoshi, Abe Yasunori, Harumi Uchima Koecklin Karin, Makiguchi Mio, Kato Chiho, Yabushita Tadachika, Michikawa Makoto, Ono Takashi. Nasal obstruction during adolescence induces memory/learning impairments associated with BDNF/TrkB signaling pathway hypofunction and high corticosterone levels JOURNAL OF NEUROSCIENCE RESEARCH. 2018.06; 96 (6): 1056-1065. ( PubMed, DOI )

  10. Uesugi Shunsuke, Imamura Toshihiro, Kokai Satoshi, Ono Takashi. Cone-beam computed tomography-based diagnosis and treatment simulation for a patient with a protrusive profile and a gummy smile KOREAN JOURNAL OF ORTHODONTICS. 2018.05; 48 (3): 189-199. ( PubMed, DOI )

  11. Hsu Jui-Chin, Watari Ippei, Funaki Yukiha, Kokai Satoshi, Ono Takashi. Unilateral nasal obstruction induces degeneration of fungiform and circumvallate papillae in rats JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION. 2018.03; 117 (3): 220-226. ( PubMed, DOI )

  12. Ikeda Yuhei, Kokai Satoshi, Ono Takashi. A patient with mandibular deviation and 3 mandibular incisors treated with asymmetrically bent improved superelastic nickel-titanium alloy wires AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS. 2018.01; 153 (1): 131-143. ( PubMed, DOI )

  13. Uesugi Shunsuke, Kokai Satoshi, Kanno Zuisei, Ono Takashi. Stability of secondarily inserted orthodontic miniscrews after failure of the primary insertion for maxillary anchorage: Maxillary buccal area vs midpalatal suture area AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS. 2018.01; 153 (1): 54-60. ( PubMed, DOI )

  14. Suzuki K, Kokai S, Uesugi S, Nishiyama A, Ono T. Evaluation of the laterality of the tissue oxygen saturation of masticatory muscles in subjects with facial asymmetry Orthodontic Waves. 2017.12; 76 (4): 232-237. ( DOI )

  15. Suzuki Katsuhiko, Kokai Satoshi, Uesugi Shunsuke, Nishiyama Akira, Ono Takashi. 顔面非対称を呈する患者における咀嚼筋群の組織酸素飽和度の側性評価(Evaluation of the laterality of the tissue oxygen saturation of masticatory muscles in subjects with facial asymmetry) Orthodontic Waves. 2017.12; 76 (4): 232-237. ( ichushi )

  16. Uesugi S, Kokai S, Kanno Z, Ono T. Prognosis of primary and secondary insertions of orthodontic miniscrews: What we have learned from 500 implants Am J Orthod Dentofacial Orthop. 2017.08; 152 (2): 224-231. ( PubMed, DOI )

  17. Uchima Koecklin Karin Harumi, 加藤 千帆, 片口 卓, 小海 暁, 小野 卓史. ラット晩期成長期における片側鼻閉は頭蓋顔面機能に影響を及ぼす(Unilateral nasal obstruction during later growth periods affects craniofacial function in rats) 口腔病学会雑誌. 2017.03; 84 (1): 55. ( ichushi )

  18. Abe Y, Kato C, Uchima Koecklin KH, Okihara H, Ishida T, Fujita K, Yabushita T, Kokai S, Ono T. Unilateral nasal obstruction affects motor representation development within the face primary motor cortex in growing rats. J Appl Physiol. 2017.01; 122 (6): 1494-1503. ( PubMed, DOI )

  19. Uchima Koecklin KH, Hiranuma M, Kato C, Funaki Y, Kataguchi T, Yabushita T, Kokai S, Ono T. Unilateral nasal obstruction during later growth periods affects craniofacial muscles in rats. Front Physiol. 2017.01; 7 (669): 1-10.

  20. Makiguchi Mio, Funaki Yukiha, Kato Chiho, Okihara Hidemasa, Ishida Takayoshi, Yabushita Tadachika, Kokai Satoshi, Ono Takashi. Effects of increased occlusal vertical dimension on the jaw-opening reflex in adult rats ARCHIVES OF ORAL BIOLOGY. 2016.12; 72 39-46. ( DOI )

  21. Watari Ippei, Hsu Jui-Chin, Ono Rieko, Funaki Yukiha, Kokai Satoshi, Ono Takashi. Degeneration of fungiform and circumvallate papillae following molar extraction and unilateral nasal obstruction in rats CHEMICAL SENSES. 2016.11; 41 (9): E272.

  22. Uesugi Shunsuke, Yonemitsu Ikuo, Kokai Satoshi, Takei Maki, Omura Susumu, Ono Takashi. Features in subjects with the frontal occlusal plane inclined toward the contralateral side of the mandibular deviation AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS. 2016.01; 149 (1): 46-54. ( DOI )

  23. Kokai Satoshi, Kanno Zuisei, Koike Sarina, Uesugi Shunsuke, Takahashi Yuzo, Ono Takashi, Soma Kunimichi. Retrospective study of 100 autotransplanted teeth with complete root formation and subsequent orthodontic treatment AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS. 2015.12; 148 (6): 982-989. ( DOI )

  24. Uchima Koecklin KH, Kato C, Funaki Y, Hiranuma M, Ishida T, Fujita K, Yabushita T, Kokai S, Ono T. Effect of unilateral nasal obstruction on tongue protrusion forces in growing rats. J Appl Physiol. 2015.05; 118 (9): 1128-1135. ( PubMed, DOI )

  25. Kokai S, Fukuyama E, Sato Y, Hsu JC, Takahashi Y, Harada K, Ono T. Comprehensive treatment approach for bilateral cleft lip and palate in an adult with premaxillary osteotomy, tooth autotransplantation, and 2-jaw surgery. Am J Orthod Dentofacial Orthop. 2015.01; 147 (1): 114-126. ( PubMed, DOI )

  26. Okihara Hidemasa, Ito Jin-Ichi, Kokai Satoshi, Ishida Takayoshi, Hiranuma Maya, Kato Chiho, Yabushita Tadachika, Ishida Kazuto, Ono Takashi, Michikawa Makoto. Liquid diet induces memory impairment accompanied by a decreased number of hippocampal neurons in mice. J Neurosci Res. 2014.08; 92 (8): 1010-1017. ( PubMed, DOI )

  27. Funaki Yukiha, Hiranuma Maya, Shibata Mai, Kokai Satoshi, Ono Takashi. Effects of nasal obstruction on maturation of the jaw-opening reflex in growing rats. Arch Oral Biol. 2014.05; 59 (5): 530-538. ( PubMed, DOI )

  28. Hiranuma M, Kokai S, Fujita K, Ishida T, Shibata M, Naito S, Yabushita T, Ono T. Effects of a liquid diet on the response properties of temporomandibular joint nociceptive neurons in the trigeminal subnucleus caudalis of growing rats. Orthod Craniofac Res. 2013.11; 16 (4): 214-222. ( PubMed, DOI )

  29. Kato C, Fujita K, Kokai S, Ishida T, Shibata M, Naito S, Yabushita T, Ono T. Increased occlusal vertical dimension induces cortical plasticity in the rat face primary motor cortex. Behav Brain Res. 2012.03; 228 (2): 254-260. ( PubMed, DOI )

  30. Naito Satomi, Ishida Takayoshi, Kokai Satoshi, Fujita Koichi, Shibata Mai, Yabushita Tadachika, Ono Takashi. Functional adaptability of temporomandibular joint mechanoreceptors after an increase in the occlusal vertical dimension in rats. Angle Orthod. 2011.05; 81 (3): 453-459. ( PubMed, DOI )

  31. Kokai Satoshi, Yabushita Tadachika, Zeredo Jorge L, Toda Kazuo, Soma Kunimichi. Functional changes of the temporomandibular joint mechanoreceptors induced by a lateral mandibular shift in rats. The Angle Orthodontist. 2007.05; 77 (3): 436-441. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Li Ruixin, Kato Chiho, Abe Yasunori, Fujita Akiyo, Ogawa Takuya, Ishidori Hideyuki, Misawa Eri, Okihara Hidemasa, Kokai Satoshi, Ono Takashi. 肥満Zuckerラットの皮質刺激による律動顎運動における神経筋動態の変化(Altered neuromuscular behavior during cortically-elicited rhythmic jaw movement in obese Zucker rat). 日本矯正歯科学会大会プログラム・抄録集 2022.10.01

  2. Akiyo Fujita, Chiho Kato, Yasunori Abe, Takuya Ogawa, Phyo Thura Aung, Hideyuki Ishidori, Ruixin Li, Hidemasa Okihara, Satoshi Kokai, Takashi Ono. Unilateral nasal obstruction affects development of motor representation in the cortical masticatory area in growing rats. 9th International Orthodontic Congress 2020.10

  3. Phyo Thura Aung, Chiho Kato, Yasunori Abe, Takuya Ogawa, Hideyuki Ishidori, Akiyo Fujita, Ruixin Li, Hidemasa Okihara, Satoshi Kokai, Takashi Ono. LOW OCCLUSAL LOADING AFFECTS THE NEUROMUSCULAR CONTROL OF JAW MOVEMENTS INDUCED BY ANTERIOR PART OF CORTICAL MASTICATORY AREA IN GROWING RATS. 9 th International Orthodontic Congress 2020.10

  4. Aung Phyo Thura, Kato Chiho, Abe Yasunori, Ogawa Takuya, Makiguchi Mio, Okihara Hidemasa, Kokai Satoshi, Ono Takashi. 成長期のラットにおいて皮質骨に誘発されるリズム性のある下顎の動きに対して咬合負荷減少が及ぼす影響(Effect of decreased occlusal loading on cortically-induced rhythmic jaw-movements in growing rats). 日本矯正歯科学会大会プログラム・抄録集 2018.10.01

  5. Takuya Ogawa, Hidemasa Okihara, Satoshi Kokai, Michikawa, Takashi Ono. Nasal obstruction induces memory and learning impairment and decreases the number of hippocampal neurons in growing mice. The 93rd congress of the European Orthodontic Society 2017.06.05 Montreux, Switzerland

  6. Katsuhiko Suzuki, Satoshi Kokai, Shun-suke Uesugi, Akira NishiyamaTakashi Ono.. Evaluation of the laterality of the tissue oxygen saturation of masticatory muscles in subjects with facial asymmetry. The 93rd congress of the European Orthodontic Society 2017.06.05 Montreux, Switzerland

  7. Kokai S, Kanno Z, Koike S, Uesugi S, Ono T. Retrospective study of 100 autotransplanted teeth with complete root formation and subsequent orthodontic treatment. 8th International Orthodontic Congress 2015.09.27 London, UK

  8. Uchima Koecklin KH, Kato C, Funaki Y, Hiranuma M, Ishida T, Fujita K, Yabushita T, Kokai S, Ono T. Increase in force and changes in the contractile characteristics of the tongue-protruding muscles after nasal obstruction in growing rats. 8th International Orthodontic Congress 2015.09.27 London, UK

  9. Chiho KATO, Koichi FUJITA, Maya HIRANUMA, Satoshi KOKAI, Tadachika YABUSHITA, Takashi ONO. Decreased volume of the oral cavity induces cortical plasticity in the rat face sensorimotor cortex. The 46th Annual Scientific Congress　Korean Association of Orthodontists 2013.10.31 Jeju, Kore

  10. Karin Harumi Uchima Koecklin, Chiho Kato, Yukiha Funaki, Maya Hiranuma, Takayoshi Ishida, Koichi Fujita, Tadachika Yabushita, Satoshi Kokai, Takashi Ono. Effect of nasal obstruction on tongue protrusion forces in growing rats. The 46th Annual Scientific Congress　Korean Association of Orthodontists 2013.10.31 Jeju, Korea

  11. Maya Hiranuma, Yukiha Funaki, Chiho Kato, Satoshi Kokai, Tadachika Yabushita, Takashi Ono. Effects of nasal obstruction at different life stages on oxygen saturation and　jaw-opening reflex. The 46th Annual Scientific Congress　Korean Association of Orthodontists 2013.10.31 Jeju, Korea

  12. Hsu Jui-chin, Watari Ippei, Funaki Yukiha, Kokai Satoshi, Ono Takashi. Unilateral nasal obstruction affects the distribution of fungiform papillae in the rat tongue. 第72回　日本矯正歯科学会学術大会 2013.10.08 松本

  13. Okihara H, Ito J, Kokai S, Ishida T, Hiranuma M, Kato C, Yabushita T, Ishida K, Michikawa M, Ono T. Association between the decrease of masticatory function and synaptic plasticity.. 2nd Meeting of the International Association of Dental Research-Asia Pacific Region 2013.08.21 Bangkok, Thailand

  14. Funaki Y, Shibata M, Hiranuma M, Kokai S, Ono T. Effects of nasal obstruction on maturation of the jaw-opening reflex in growing rats.. 89th Congress of the European Orthodontic Society 2013.03.26 European Orthodontic Society

  15. Satomi NAITO, Satoshi KOKAI, Takayoshi ISHIDA, Koichi FUJITA, Mai SHIBATA,Chiho KATO, Maya HIRANUMA, Tadachika YABUSHITA, Takashi ONO. Functional changes of the temporomandibular joint mechanoreceptors induced by temporomandibular joint resorption in rats. The 45th Annual Scientific Congress Korean Association of Orthodontists 2012.11.01 Seoul, Korea

  16. Shindoi Jose-Maria、佐藤豊、松本芳郎、金香佐和、島崎一夫、小海暁、柴田真衣、山城正司、原田清、小野卓史. Soft-tissue cephalometric norms for orthognathic surgery in Jaoanese adults. 第22回日本顎変形症学会総会・学術大会 2012.06.18 福岡

  17. Satomi Naito, Takayoshi Ishida, Satoshi Kokai, Koichi Fujita, Mai Shibata, Tadachika Yabushita,　Takashi Ono. Functional adaptability of　temporomandibular joint mechanoreceptors after　an increase in the occlusal vertical dimension　in rats. 87th Congress of the European Orthodontic Society 2011.06.19 Istanbul, Turkey

  18. Chiho KATO, Koichi FUJITA, Satoshi KOKAI, Tadachika YABUSHITA, Takashi ONO. Effects of increased occlusal vertical dimension on motor representations within the face motor cortex of adult rats. 87th Congress of the European Orthodontic Society 2011.06.19 Istanbul, Turkey

  19. Maya HIRANUMA, Satoshi KOKAI, Koji FUJITA, Tadachika YABUSHITA, Takashi ONO. Effects of low masticatory loading on the response properties of temporomandibular joint-nociceptors in growing rats. 87th Congress of the European Orthodontic Society 2011.06.19 Istanbul, Turkey

  20. KOKAI S., YABUSHITA T.,ZEREDO JL., TODA K., SOMA K.　. An electrophysiological study on functional changes of rat temporomandibular joint mechanoreceptors induced by lateral shift of the mandible. 第1回国際顎関節学会ならびに第19回日本顎関節学会総会・学術大会 2006.07.19 名古屋

  21. Satoshi KOKAI、Tadachika YABUSHITA, Zeredo Jorge L, Kazuo TODA, Kunimichi SOMA. Changes in response properties of TMJ mechanoreceptors by lateral functional shift of the mandible in rats. 第28回日本神経科学大会 2005.07.26 横浜

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Awards & Honors 【 display / non-display 】

  • Ogawa T. The 76th Annual Meeting of the Japanese Orthodontic Society, Excellent Exhibition Award，Japanese Orthodontic Society，2017.10

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