Xin Z, Yamaguchi A, Sakamoto K. Aberrant expression and altered cellular localization of desmosomal and hemidesmosomal proteins are associated with aggressive clinicopathological features of oral squamous cell carcinoma. Virchows Arch.. 2014.07; 465 (1): 35-47. ( PubMed, DOI )

Ji-Won Lee, Akira Yamaguchi, Tadahiro Iimura. Functional heterogeneity of osteocytes in FGF23 production: the possible involvement of DMP1 as a direct negative regulator. Bonekey Rep. 2014; 3 543. ( PubMed, DOI )

Masamitsu Oshima, Kaoru Inoue, Kei Nakajima, Tetsuhiko Tachikawa, Hiromichi Yamazaki, Tomohide Isobe, Ayaka Sugawara, Miho Ogawa, Chie Tanaka, Masahiro Saito, Shohei Kasugai, Teruko Takano-Yamamoto, Takashi Inoue, Katsunari Tezuka, Takuo Kuboki, Akira Yamaguchi, Takashi Tsuji. Functional tooth restoration by next-generation bio-hybrid implant as a bio-hybrid artificial organ replacement therapy. Sci Rep. 2014; 4 6044. ( PubMed, DOI )

Yuki Matsushita, Kei Sakamoto, Yoshihiro Tamamura, Yasuaki Shibata, Tokutaro Minamizato, Tasuku Kihara, Masako Ito, Ken-ichi Katsube, Shuichi Hiraoka, Haruhiko Koseki, Kiyoshi Harada, Akira Yamaguchi. CCN3 protein participates in bone regeneration as an inhibitory factor. J. Biol. Chem.. 2013.07; 288 (27): 19973-19985. ( PubMed, DOI )

Yumi Mochizuki, Ken Omura, Kae Tanaka, Kei Sakamoto, Akira Yamaguchi. Myoepithelioma of the Parotid Gland Presenting as a Retroauricular Cutaneous nodule: A Case Report. J Clin Diagn Res. 2013.06; 7 (6): 1165-1168. ( PubMed, DOI )

Rieko Tanabe, Mayu Haraikawa, Natsuko Sogabe, Aoi Sugimoto, Yuka Kawamura, Satoshi Takasugi, Masashi Nagata, Ayako Nakane, Akira Yamaguchi, Tadahiro Iimura, Masae Goseki-Sone. Retention of bone strength by feeding of milk and dairy products in ovariectomized rats: involvement of changes in serum levels of 1alpha, 25(OH)2D3 and FGF23. J. Nutr. Biochem.. 2013.06; 24 (6): 1000-1007. ( PubMed, DOI )

Kiyoshi Sato, Ji-Won Lee, Kei Sakamoto, Tadahiro Iimura, Kou Kayamori, Hisataka Yasuda, Masanobu Shindoh, Masako Ito, Ken Omura, Akira Yamaguchi. RANKL synthesized by both stromal cells and cancer cells plays a crucial role in osteoclastic bone resorption induced by oral cancer. Am. J. Pathol.. 2013.05; 182 (5): 1890-1899. ( PubMed, DOI )

T Matsumoto, T Iimura, K Ogura, K Moriyama, A Yamaguchi. The role of osteocytes in bone resorption during orthodontic tooth movement. J. Dent. Res.. 2013.04; 92 (4): 340-345. ( PubMed, DOI )

Samir Kumar Pal, Kei Sakamoto, Tadanobu Aragaki, Takumi Akashi, Akira Yamaguchi. The expression profiles of acidic epithelial keratins in ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013.04; 115 (4): 523-531. ( PubMed, DOI )

Yuji Makino, Yu Takahashi, Rieko Tanabe, Yoshihiro Tamamura, Takashi Watanabe, Mayu Haraikawa, Miwako Hamagaki, Kenji Hata, Jun Kanno, Toshiyuki Yoneda, Yumiko Saga, Masae Goseki-Sone, Kazuo Kaneko, Akira Yamaguchi, Tadahiro Iimura. Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013.03; 53 (1): 248-258. ( PubMed, DOI )

Akiyoshi Hoshino, Satoshi Ueha, Sanshiro Hanada, Toshio Imai, Masako Ito, Kenji Yamamoto, Kouji Matsushima, Akira Yamaguchi, Tadahiro Iimura. Roles of chemokine receptor CX3CR1 in maintaining murine bone homeostasis through the regulation of both osteoblasts and osteoclasts. J. Cell. Sci.. 2013.02; 126 (Pt 4): 1032-1045. ( PubMed, DOI )

Makino Y, Kaneko K, Yamaguchi A, Iimura T. Developmental biology and etiology of axial skeleton: Lessons from a mouse model of spondylocostal dysostosis and spondylothoracic dysostosis. J Oral Biosci. 2013; 55 175-179.

Yasuyuki Shimada, Ken-ichi Katsube, Yuji Kabasawa, Kei-ichi Morita, Ken Omura, Akira Yamaguchi, Kei Sakamoto. Integrated genotypic analysis of hedgehog-related genes identifies subgroups of keratocystic odontogenic tumor with distinct clinicopathological features. PLoS ONE. 2013; 8 (8): e70995. ( PubMed, DOI )

Takashi Watanabe, Yoshihiro Tamamura, Akiyoshi Hoshino, Yuji Makino, Hiroshi Kamioka, Teruo Amagasa, Akira Yamaguchi, Tadahiro Iimura. Increasing participation of sclerostin in postnatal bone development, revealed by three-dimensional immunofluorescence morphometry. Bone. 2012.09; 51 (3): 447-458. ( PubMed, DOI )

Riko Nishimura, Makoto Wakabayashi, Kenji Hata, Takuma Matsubara, Shiho Honma, Satoshi Wakisaka, Hiroshi Kiyonari, Go Shioi, Akira Yamaguchi, Noriyuki Tsumaki, Haruhiko Akiyama, Toshiyuki Yoneda. Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification. J. Biol. Chem.. 2012.09; 287 (40): 33179-33190. ( PubMed, DOI )

Kei Sakamoto, Rumana Khanom, Miwako Hamagaki, Akira Yamaguchi. Ectopic production of hair keratin constitutes Rushton's hyaline bodies in association with hematogenous deposits. J. Oral Pathol. Med.. 2012.09; 41 (8): 637-641. ( PubMed, DOI )

Kohsuke Umehara, Tadahiro Iimura, Kei Sakamoto, Zayar Lin, Shohei Kasugai, Yoshimasa Igarashi, Akira Yamaguchi. Canine oral mucosal fibroblasts differentiate into osteoblastic cells in response to BMP-2. Anat Rec (Hoboken). 2012.08; 295 (8): 1327-1335. ( PubMed, DOI )

Erika Oue, Ji-Won Lee, Kei Sakamoto, Tadahiro Iimura, Kazuhiro Aoki, Kou Kayamori, Yasuyuki Michi, Masashi Yamashiro, Kiyoshi Harada, Teruo Amagasa, Akira Yamaguchi. CXCL2 synthesized by oral squamous cell carcinoma is involved in cancer-associated bone destruction. Biochem. Biophys. Res. Commun.. 2012.08; 424 (3): 456-461. ( PubMed, DOI )

Rumana Khanom, Kei Sakamoto, Samir Kumar Pal, Yasuyuki Shimada, Kei-ichi Morita, Ken Omura, Yoshio Miki, Akira Yamaguchi. Expression of basal cell keratin 15 and keratin 19 in oral squamous neoplasms represents diverse pathophysiologies. Histol. Histopathol.. 2012.07; 27 (7): 949-959. ( PubMed )

K Horiguchi, K Sakamoto, D Koinuma, K Semba, A Inoue, S Inoue, H Fujii, A Yamaguchi, K Miyazawa, K Miyazono, M Saitoh. TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP. Oncogene. 2012.06; 31 (26): 3190-3201. ( PubMed, DOI )

Midori Asai, Ji-Won Lee, Yasunori Itakura, Bong-Keun Choi, Takayuki Yonezawa, Toshiaki Teruya, Byung-Yoon Cha, Motoko Ohnishi, Akira Yamaguchi, Je-Tae Woo. Effects of veraguensin and galgravin on osteoclast differentiation and function. Cytotechnology. 2012.05; 64 (3): 315-322. ( PubMed, DOI )

Tadahiro Iimura, Ayako Nakane, Mayu Sugiyama, Hiroki Sato, Yuji Makino, Takashi Watanabe, Yuzo Takagi, Rika Numano, Akira Yamaguchi. A fluorescence spotlight on the clockwork development and metabolism of bone. J. Bone Miner. Metab.. 2012.05; 30 (3): 254-269. ( PubMed, DOI )

Kei Sakamoto, Takuma Fujii, Hiroshi Kawachi, Yoshio Miki, Ken Omura, Kei-ichi Morita, Kou Kayamori, Ken-ichi Katsube, Akira Yamaguchi. Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms. Lab. Invest.. 2012.05; 92 (5): 688-702. ( PubMed, DOI )

Chieko Michikawa, Narikazu Uzawa, Kou Kayamori, Itaru Sonoda, Yoshio Ohyama, Norihiko Okada, Akira Yamaguchi, Teruo Amagasa. Clinical significance of lymphatic and blood vessel invasion in oral tongue squamous cell carcinomas. Oral Oncol.. 2012.04; 48 (4): 320-324. ( PubMed, DOI )

Akiko Himeno-Ando, Yuichi Izumi, Akira Yamaguchi, Tadahiro Iimura. Structural differences in the osteocyte network between the calvaria and long bone revealed by three-dimensional fluorescence morphometry, possibly reflecting distinct mechano-adaptations and sensitivities. Biochem. Biophys. Res. Commun.. 2012.01; 417 (2): 765-770. ( PubMed, DOI )

Ryo Aizawa, Atsushi Yamada, Dai Suzuki, Tadahiro Iimura, Hidetoshi Kassai, Takeshi Harada, Masayuki Tsukasaki, Gou Yamamoto, Tetsuhiko Tachikawa, Kazuki Nakao, Matsuo Yamamoto, Akira Yamaguchi, Atsu Aiba, Ryutaro Kamijo. Cdc42 is required for chondrogenesis and interdigital programmed cell death during limb development. Mech. Dev.. 2012; 129 (1-4): 38-50. ( PubMed, DOI )

Chang X, Lu Y, Shibata Y, Tsukazaki T, Yamaguchi A. Role of bone morphogenetic proteins and their antagonists during fracture healing. J Hard Tissue Biol . 2012; 21 203-212.

Lei Cao, Takeshi Moriishi, Toshihiro Miyazaki, Tadahiro Iimura, Miwako Hamagaki, Ayako Nakane, Yoshihiro Tamamura, Toshihisa Komori, Akira Yamaguchi. Comparative morphology of the osteocyte lacunocanalicular system in various vertebrates. J. Bone Miner. Metab.. 2011.11; 29 (6): 662-670. ( PubMed, DOI )

飯村 忠浩, 杉山 真由, 牧野 祐司, 中根 綾子, 渡辺 高, 山口 朗. 脊椎動物の発生におけるライブイメージング Cytometry Research. 2011.03; 21 (1): 57-63. ( ichushi )

Kei Sakamoto, Tadanobu Aragaki, Kei-ichi Morita, Hiroshi Kawachi, Kou Kayamori, Shoichi Nakanishi, Ken Omura, Yoshio Miki, Norihiko Okada, Ken-Ichi Katsube, Toichiro Takizawa, Akira Yamaguchi. Down-regulation of keratin 4 and keratin 13 expression in oral squamous cell carcinoma and epithelial dysplasia: a clue for histopathogenesis. Histopathology. 2011.03; 58 (4): 531-542. ( PubMed, DOI )

Tasuku Kihara, Saki Ichikawa, Takayuki Yonezawa, Ji-Won Lee, Toshihiro Akihisa, Je Tae Woo, Yasuyuki Michi, Teruo Amagasa, Akira Yamaguchi. Acerogenin A, a natural compound isolated from Acer nikoense Maxim, stimulates osteoblast differentiation through bone morphogenetic protein action. Biochem. Biophys. Res. Commun.. 2011.03; 406 (2): 211-217. ( PubMed, DOI )

Iimura T, Sugiyama M, Makino Y, Nakane A, Watanabe T, Yamaguchi A. Illumination of vertebrate development by fluorescence live imaging. Cytometry Research. 2011; 21 57-63.

Yumi Mochizuki, Ken Omura, Kou Kayamori, Kei Sakamoto, Hiroaki Shimamoto, Akira Yamaguchi. Küttner's tumor of the sub-mandibular gland associated with fibrosclerosis and follicular hyperplasia of regional lymph nodes: a case report. J Med Case Rep. 2011; 5 121. ( PubMed, DOI )

Toru Yanagawa, Akira Yamaguchi, Hiroyuki Harada, Kenji Yamagata, Naomi Ishibashi, Masayuki Noguchi, Kojiro Onizawa, Hiroki Bukawa. Cheilitis glandularis: two case reports of asian-Japanese men and literature review of Japanese cases. ISRN Dent. 2011; 2011 457567. ( PubMed, DOI )

Tadanobu Aragaki, Yasuyuki Michi, Ken-ichi Katsube, Narikazu Uzawa, Norihiko Okada, Takumi Akashi, Teruo Amagasa, Akira Yamaguchi, Kei Sakamoto. Comprehensive keratin profiling reveals different histopathogenesis of keratocystic odontogenic tumor and orthokeratinized odontogenic cyst. Hum. Pathol.. 2010.12; 41 (12): 1718-1725. ( PubMed, DOI )

Masaya Etoh, Akira Yamaguchi. Repetition of continuous PTH treatments followed by periodic withdrawals exerts anabolic effects on rat bone. J. Bone Miner. Metab.. 2010.11; 28 (6): 641-649. ( PubMed, DOI )

Keizo Nishikawa, Tomoki Nakashima, Shu Takeda, Masashi Isogai, Michito Hamada, Ayako Kimura, Tatsuhiko Kodama, Akira Yamaguchi, Michael J Owen, Satoru Takahashi, Hiroshi Takayanagi. Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation. J. Clin. Invest.. 2010.10; 120 (10): 3455-3465. ( PubMed, DOI )

Akiyoshi Hoshino, Tadahiro Iimura, Satoshi Ueha, Sanshiro Hanada, Yutaka Maruoka, Mitsuori Mayahara, Keiko Suzuki, Toshio Imai, Masako Ito, Yoshinobu Manome, Masato Yasuhara, Takaaki Kirino, Akira Yamaguchi, Kouji Matsushima, Kenji Yamamoto. Deficiency of chemokine receptor CCR1 causes osteopenia due to impaired functions of osteoclasts and osteoblasts. J. Biol. Chem.. 2010.09; 285 (37): 28826-28837. ( PubMed, DOI )

Yumi Mochizuki, Ken Omura, Kei Sakamoto, Shoichi Nakanishi, Kiyoshi Satoh, Eriko Marukawa, Akira Yamaguchi. A case of primary combined neuroendocrine carcinoma with squamous cell carcinoma in the upper gingiva. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010.04; 109 (4): e34-e39. ( PubMed, DOI )

Kou Kayamori, Kei Sakamoto, Tomoki Nakashima, Hiroshi Takayanagi, Kei-Ichi Morita, Ken Omura, Su Tien Nguyen, Yoshio Miki, Tadahiro Iimura, Akiko Himeno, Takumi Akashi, Hisafumi Yamada-Okabe, Etsuro Ogata, Akira Yamaguchi. Roles of interleukin-6 and parathyroid hormone-related peptide in osteoclast formation associated with oral cancers: significance of interleukin-6 synthesized by stromal cells in response to cancer cells. Am. J. Pathol.. 2010.02; 176 (2): 968-980. ( PubMed, DOI )

Iimura T, Himeno A, Nakane A, Yamaguchi A. Hox genes, a molecular constraint for development and evolution of vertebrate body plan. J Oral Biosci. 2010; 52 155-163.

MochizukiY, Omura K, Harada H, Kayamori K, Okada N, Yamaguchi A. Malignant fibrous histiocytoma of the jaws: A report of 3 cases. Asian J Oral Maxillofacial Surg. 2010; 22 143-147.

Ken-Ichi Katsube, Saki Ichikawa, Yuko Katsuki, Tasuku Kihara, Masanori Terai, Lester F Lau, Yoshihiro Tamamura, Shin'ichi Takeda, Akihiro Umezawa, Kei Sakamoto, Akira Yamaguchi. CCN3 and bone marrow cells. J Cell Commun Signal. 2009.06; 3 (2): 135-145. ( PubMed, DOI )

Shoichi Nakanishi, Kei Sakamoto, Kei Sskamoto, Hiroyuki Yoshitake, Koji Kino, Teruo Amagasa, Akira Yamaguchi. Bone morphogenetic proteins are involved in the pathobiology of synovial chondromatosis. Biochem. Biophys. Res. Commun.. 2009.02; 379 (4): 914-919. ( PubMed, DOI )

Ichiro Kadouchi, Kei Sakamoto, Liu Tangjiao, Takashi Murakami, Eiji Kobayashi, Yuichi Hoshino, Akira Yamaguchi. Latexin is involved in bone morphogenetic protein-2-induced chondrocyte differentiation. Biochem. Biophys. Res. Commun.. 2009.01; 378 (3): 600-604. ( PubMed, DOI )

Ken-ichi Katsube, Kei Sakamoto, Yoshihiro Tamamura, Akira Yamaguchi. Role of CCN, a vertebrate specific gene family, in development. Dev. Growth Differ.. 2009.01; 51 (1): 55-67. ( PubMed, DOI )

Katsube K, Sakamoto K, Tamamura Y, Yamaguchi A. CCN, a vertebrate specific gene family and Development. Dev, Growth Differ. 2009; 51 55067.

Mochizuki Y, Omura K, Kaneoya K, Kayamori K, Yamaguchi A. Osteonecrosis of the mandible associated with bisphosphonate therapy; report of a case with surgical intervention. Oral Surg. 2009; 2 153-157.

Kawai S, ItoE, Yamaguchi A, Eishi Y, Okada N. Immunohistochemical characteristics of odontogenic carcinomas: their use in diagnosing and elucidating histogenesis. Oral Medicine & Pathology. 2009; 13 56-63.

Riko Kitazawa, Kiyoshi Mori, Akira Yamaguchi, Takeshi Kondo, Sohei Kitazawa. Modulation of mouse RANKL gene expression by Runx2 and vitamin D3. J. Cell. Biochem.. 2008.12; 105 (5): 1289-1297. ( PubMed, DOI )

N Matsuda, K Katsube, S Mikami, Y Katsuki, H Iseki, M Mukai, A Yamaguchi, Y Takano, T Nakajima, H Nakajima, K Kishi. E-cadherin expression in the subepithelial nevus cells of the giant congenital nevocellular nevi (GCNN) correlates with their migration ability in vitro. J. Dermatol. Sci.. 2008.10; 52 (1): 21-30. ( PubMed, DOI )

Takuma Matsubara, Kumiko Kida, Akira Yamaguchi, Kenji Hata, Fumitaka Ichida, Hiroko Meguro, Hiroyuki Aburatani, Riko Nishimura, Toshiyuki Yoneda. BMP2 regulates Osterix through Msx2 and Runx2 during osteoblast differentiation. J. Biol. Chem.. 2008.10; 283 (43): 29119-29125. ( PubMed, DOI )

Masafumi Ishikuro, Kei Sakamoto, Kou Kayamori, Takumi Akashi, Hiroaki Kanda, Toshiyuki Izumo, Akira Yamaguchi. Significance of the fibrous stroma in bone invasion by human gingival squamous cell carcinomas. Bone. 2008.09; 43 (3): 621-627. ( PubMed, DOI )

Y Kabasawa, K Nagumo, Y Takeda, N Kawashima, N Okada, K Omura, A Yamaguchi, K Katsube. Amelogenin positive cells scattered in the interstitial component of odontogenic fibromas. J. Clin. Pathol.. 2008.07; 61 (7): 851-855. ( PubMed, DOI )

Kei Sakamoto, Yoshihiro Tamamura, Ken-ichi Katsube, Akira Yamaguchi. Zfp64 participates in Notch signaling and regulates differentiation in mesenchymal cells. J. Cell. Sci.. 2008.05; 121 (Pt 10): 1613-1623. ( PubMed, DOI )

H Kitaura, M Yoshimatsu, Y Fujimura, T Eguchi, H Kohara, A Yamaguchi, N Yoshida. An anti-c-Fms antibody inhibits orthodontic tooth movement. J. Dent. Res.. 2008.04; 87 (4): 396-400. ( PubMed )

Yuko Katsuki, Kei Sakamoto, Tokutaro Minamizato, Hatsune Makino, Akihiro Umezawa, Masa-Aki Ikeda, Bernard Perbal, Teruo Amagasa, Akira Yamaguchi, Ken-Ichi Katsube. Inhibitory effect of CT domain of CCN3/NOV on proliferation and differentiation of osteogenic mesenchymal stem cells, Kusa-A1. Biochem. Biophys. Res. Commun.. 2008.04; 368 (3): 808-814. ( PubMed, DOI )

Takeshi Kondo, Riko Kitazawa, Akira Yamaguchi, Sohei Kitazawa. Dexamethasone promotes osteoclastogenesis by inhibiting osteoprotegerin through multiple levels. J. Cell. Biochem.. 2008.01; 103 (1): 335-345. ( PubMed, DOI )

Yamaguchi A, Sakamoto K, Minamizato T, Katsube K, Nakanishi S. Regulation of osteoblast differentiation mediated by BMP, Notch, and CCN3/NOV. Jap Dent Sci Revi. . 2008; 44 48-56.

Atsuko Shimoyama, Masahiro Wada, Fumiyo Ikeda, Kenji Hata, Takuma Matsubara, Akira Nifuji, Masaki Noda, Katsuhiko Amano, Akira Yamaguchi, Riko Nishimura, Toshiyuki Yoneda. Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function. Mol. Biol. Cell. 2007.07; 18 (7): 2411-2418. ( PubMed, DOI )

Tingjiao Liu, Yuhao Gao, Kei Sakamoto, Tokutaro Minamizato, Keizo Furukawa, Tomoo Tsukazaki, Yasuaki Shibata, Kazuhisa Bessho, Toshihisa Komori, Akira Yamaguchi. BMP-2 promotes differentiation of osteoblasts and chondroblasts in Runx2-deficient cell lines. J. Cell. Physiol.. 2007.06; 211 (3): 728-735. ( PubMed, DOI )

Tokutaro Minamizato, Kei Sakamoto, Tingjiao Liu, Hiroki Kokubo, Ken-ichi Katsube, Bernard Perbal, Seiji Nakamura, Akira Yamaguchi. CCN3/NOV inhibits BMP-2-induced osteoblast differentiation by interacting with BMP and Notch signaling pathways. Biochem. Biophys. Res. Commun.. 2007.03; 354 (2): 567-573. ( PubMed, DOI )

Molecular basis of bone regeneration and its application to development of cell-mediated therapy for bone repair. J Oral Tissue Engin 4. 2007; 117-120.

Kazunari Hirata, Akio Mizuno, Akira Yamaguchi. Transplantation of skin fibroblasts expressing BMP-2 contributes to the healing of critical-sized bone defects. J. Bone Miner. Metab.. 2007; 25 (1): 6-11. ( PubMed, DOI )

Kojiro Sato, Ayako Suematsu, Tomoki Nakashima, Sayaka Takemoto-Kimura, Kazuhiro Aoki, Yasuyuki Morishita, Hiroshi Asahara, Keiichi Ohya, Akira Yamaguchi, Toshiyuki Takai, Tatsuhiko Kodama, Talal A Chatila, Haruhiko Bito, Hiroshi Takayanagi. Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat. Med.. 2006.12; 12 (12): 1410-1416. ( PubMed, DOI )

Kojiro Sato, Ayako Suematsu, Kazuo Okamoto, Akira Yamaguchi, Yasuyuki Morishita, Yuho Kadono, Sakae Tanaka, Tatsuhiko Kodama, Shizuo Akira, Yoichiro Iwakura, Daniel J Cua, Hiroshi Takayanagi. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J. Exp. Med.. 2006.11; 203 (12): 2673-2682. ( PubMed, DOI )

N Soedarsono, D Rabello, H Kamei, D Fuma, Y Ishihara, M Suzuki, T Noguchi, Y Sakaki, A Yamaguchi, T Kojima. Evaluation of RANK/RANKL/OPG gene polymorphisms in aggressive periodontitis. J. Periodont. Res.. 2006.10; 41 (5): 397-404. ( PubMed, DOI )

D Rabello, N Soedarsono, H Kamei, Y Ishihara, T Noguchi, D Fuma, M Suzuki, Y Sakaki, A Yamaguchi, T Kojima. CSF1 gene associated with aggressive periodontitis in the Japanese population. Biochem. Biophys. Res. Commun.. 2006.09; 347 (3): 791-796. ( PubMed, DOI )

Kiyoshi Mori, Riko Kitazawa, Takeshi Kondo, Sakan Maeda, Akira Yamaguchi, Sohei Kitazawa. Modulation of mouse RANKL gene expression by Runx2 and PKA pathway. J. Cell. Biochem.. 2006.08; 98 (6): 1629-1644. ( PubMed, DOI )

Kazuhiro Aoki, Hiroaki Saito, Cecile Itzstein, Masaji Ishiguro, Tatsuya Shibata, Roland Blanque, Anower Hussain Mian, Mariko Takahashi, Yoshifumi Suzuki, Masako Yoshimatsu, Akira Yamaguchi, Pierre Deprez, Patrick Mollat, Ramachandran Murali, Keiichi Ohya, William C Horne, Roland Baron. A TNF receptor loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone loss. J. Clin. Invest.. 2006.06; 116 (6): 1525-1534. ( PubMed, DOI )

Yonemoto M, Yusa H, Yamagata K, Fujita S, Yamaguchi A, Yoshida H. Squamous cell carcinoma of the base of tongue with initial presentation of cystic metastasis in contralateral cervical lymph node. Oral Oncology Extra. 2006; 42 56-59.

Masako Yoshimatsu, Yasuaki Shibata, Hideki Kitaura, Xin Chang, Takeshi Moriishi, Fumio Hashimoto, Noriaki Yoshida, Akira Yamaguchi. Experimental model of tooth movement by orthodontic force in mice and its application to tumor necrosis factor receptor-deficient mice. J. Bone Miner. Metab.. 2006; 24 (1): 20-27. ( PubMed, DOI )

Tingjiao Liu, Enxin Zhu, Lihong Wang, Toshie Okada, Akira Yamaguchi, Norihiko Okada. Abnormal expression of Rb pathway-related proteins in salivary gland acinic cell carcinoma. Hum. Pathol.. 2005.09; 36 (9): 962-970. ( PubMed, DOI )

Masuhiro Nobta, Tomoo Tsukazaki, Yasuaki Shibata, Chang Xin, Takeshi Moriishi, Seiji Sakano, Hiroyuki Shindo, Akira Yamaguchi. Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling. J. Biol. Chem.. 2005.04; 280 (16): 15842-15848. ( PubMed, DOI )

Takeshi Moriishi, Yasuaki Shibata, Tomoo Tsukazaki, Akira Yamaguchi. Expression profile of Xenopus banded hedgehog, a homolog of mouse Indian hedgehog, is related to the late development of endochondral ossification in Xenopus laevis. Biochem. Biophys. Res. Commun.. 2005.03; 328 (4): 867-873. ( PubMed, DOI )

Kenji Hata, Riko Nishimura, Mio Ueda, Fumiyo Ikeda, Takuma Matsubara, Fumitaka Ichida, Kunihiro Hisada, Takashi Nokubi, Akira Yamaguchi, Toshiyuki Yoneda. A CCAAT/enhancer binding protein beta isoform, liver-enriched inhibitory protein, regulates commitment of osteoblasts and adipocytes. Mol. Cell. Biol.. 2005.03; 25 (5): 1971-1979. ( PubMed, DOI )

Tu Ngoc Tran, Yenchun Liu, Minoru Takagi, Akira Yamaguchi, Hiroaki Fujii. Frequent promoter hypermethylation of RASSF1A and p16INK4a and infrequent allelic loss other than 9p21 in betel-associated oral carcinoma in a Vietnamese non-smoking/non-drinking female population. J. Oral Pathol. Med.. 2005.03; 34 (3): 150-156. ( PubMed, DOI )

Kei Sakamoto, Wang Sheng Chao, Ken-ichi Katsube, Akira Yamaguchi. Distinct roles of EGF repeats for the Notch signaling system. Exp. Cell Res.. 2005.01; 302 (2): 281-291. ( PubMed, DOI )

Sakamoto K, Sawai T, Yamaguchi A. Solitary fibrous tumor of the tongue. Oral Oncology Extra. 2005; 41 191-252.

Yasuaki Shibata, Tomoo Tsukazaki, Kazunari Hirata, Cheng Xin, Akira Yamaguchi. Role of a new member of IGFBP superfamily, IGFBP-rP10, in proliferation and differentiation of osteoblastic cells. Biochem. Biophys. Res. Commun.. 2004.12; 325 (4): 1194-1200. ( PubMed, DOI )

Michitaka Notoya, Eri Otsuka, Akira Yamaguchi, Hiromi Hagiwara. Runx-2 is not essential for the vitamin D-regulated expression of RANKL and osteoprotegerin in osteoblastic cells. Biochem. Biophys. Res. Commun.. 2004.11; 324 (2): 655-660. ( PubMed, DOI )

Y Doiguchi, T Tsukazaki, T Tomonaga, M Nobuta, S Fujita, T Hayashi, K Nagai, T Matsumoto, H Shindo, A Yamaguchi. Establishment of a clonal human mesenchymal cell line that retains multilineage differentiation capacity from a spinal hamartoma. Cell Tissue Res.. 2004.09; 317 (3): 237-246. ( PubMed, DOI )

Fumitaka Ichida, Riko Nishimura, Kenji Hata, Takuma Matsubara, Fumiyo Ikeda, Kunihiro Hisada, Hirofumi Yatani, Xu Cao, Toshihisa Komori, Akira Yamaguchi, Toshiyuki Yoneda. Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation. J. Biol. Chem.. 2004.08; 279 (32): 34015-34022. ( PubMed, DOI )

Toru Yanagawa, Ken Itoh, Junya Uwayama, Yasuaki Shibata, Akira Yamaguchi, Tsuneyoshi Sano, Tetsuro Ishii, Hiroshi Yoshida, Masayuki Yamamoto. Nrf2 deficiency causes tooth decolourization due to iron transport disorder in enamel organ. Genes Cells. 2004.07; 9 (7): 641-651. ( PubMed, DOI )

A Kadowaki, T Tsukazaki, K Hirata, Y Shibata, Y Okubo, K Bessho, T Komori, N Yoshida, A Yamaguchi. Isolation and characterization of a mesenchymal cell line that differentiates into osteoblasts in response to BMP-2 from calvariae of GFP transgenic mice. Bone. 2004.06; 34 (6): 993-1003. ( PubMed, DOI )

Shuichi Fujita, Nathan Buziba, Atsushi Kumatori, Masachika Senba, Akira Yamaguchi, Kan Toriyama. Early stage of Epstein-Barr virus lytic infection leading to the "starry sky" pattern formation in endemic Burkitt lymphoma. Arch. Pathol. Lab. Med.. 2004.05; 128 (5): 549-552. ( PubMed, DOI )

Kimitoshi Yagami, Yohei Uyama, Yasumasa Yoshizawa, Saburo Kakuta, Akira Yamaguchi, Masao Nagumo. A human chondrogenic cell line retains multi-potency that differentiates into osteoblasts and adipocytes. Bone. 2004.04; 34 (4): 648-655. ( PubMed, DOI )

Yoko Ichikawa, Misa Sumi, Nobu Ohwatari, Toshihisa Komori, Tadateru Sumi, Hiroaki Shibata, Tatsuya Furuichi, Akira Yamaguchi, Takashi Nakamura. Evaluation of 9.4-T MR microimaging in assessing normal and defective fetal bone development: comparison of MR imaging and histological findings. Bone. 2004.04; 34 (4): 619-628. ( PubMed, DOI )

Kentaro Shindo, Nobuyuki Kawashima, Kei Sakamoto, Akira Yamaguchi, Akihiro Umezawa, Minoru Takagi, Ken-ichi Katsube, Hideaki Suda. Osteogenic differentiation of the mesenchymal progenitor cells, Kusa is suppressed by Notch signaling. Exp. Cell Res.. 2003.11; 290 (2): 370-380. ( PubMed )

Takashi Iioka, Keizo Furukawa, Akira Yamaguchi, Hiroyuki Shindo, Shunichi Yamashita, Tomoo Tsukazaki. P300/CBP acts as a coactivator to cartilage homeoprotein-1 (Cart1), paired-like homeoprotein, through acetylation of the conserved lysine residue adjacent to the homeodomain. J. Bone Miner. Res.. 2003.08; 18 (8): 1419-1429. ( PubMed, DOI )

K Hirata, T Tsukazaki, A Kadowaki, K Furukawa, Y Shibata, T Moriishi, Y Okubo, K Bessho, T Komori, A Mizuno, A Yamaguchi. Transplantation of skin fibroblasts expressing BMP-2 promotes bone repair more effectively than those expressing Runx2. Bone. 2003.05; 32 (5): 502-512. ( PubMed )

Tatsuo Shirota, Mie Tashiro, Kohsuke Ohno, Akira Yamaguchi. Effect of intermittent parathyroid hormone (1-34) treatment on the bone response after placement of titanium implants into the tibia of ovariectomized rats. J. Oral Maxillofac. Surg.. 2003.04; 61 (4): 471-480. ( PubMed, DOI )

Kensuke Ochi, Gouping Chen, Takashi Ushida, Satoshi Gojo, Kaoru Segawa, Hitoshi Tai, Kenju Ueno, Hiroyuki Ohkawa, Taisuke Mori, Akira Yamaguchi, Yoshiaki Toyama, Jun-Ichi Hata, Akihiro Umezawa. Use of isolated mature osteoblasts in abundance acts as desired-shaped bone regeneration in combination with a modified poly-DL-lactic-co-glycolic acid (PLGA)-collagen sponge. J. Cell. Physiol.. 2003.01; 194 (1): 45-53. ( PubMed, DOI )

Yuki Tokugawa, Tatsuo Shirota, Kohsuke Ohno, Akira Yamaguchi. Effects of bisphosphonate on bone reaction after placement of titanium implants in tibiae of ovariectomized rats. Int J Oral Maxillofac Implants. 2003; 18 (1): 66-74. ( PubMed )

Takahito Yuasa, Hiroko Kataoka, Naoki Kinto, Masahiro Iwamoto, Motomi Enomoto-Iwamoto, Shun-Ichiro Iemura, Naoto Ueno, Yasuaki Shibata, Hisashi Kurosawa, Akira Yamaguchi. Sonic hedgehog is involved in osteoblast differentiation by cooperating with BMP-2. J. Cell. Physiol.. 2002.11; 193 (2): 225-232. ( PubMed, DOI )

Keizo Furukawa, Takashi Iioka, Mariko Morishita, Akira Yamaguchi, Hiroyuki Shindo, Hiroyuki Namba, Shunichi Yamashita, Tomoo Tsukazaki. Functional domains of paired-like homeoprotein Cart1 and the relationship between dimerization and transcription activity. Genes Cells. 2002.11; 7 (11): 1135-1147. ( PubMed )

Shin-ichi Yamada, Takemitsu Matsuo, Shuichi Fujita, Kazutaka Suyama, Akira Yamaguchi, Akio Mizuno. Mucoepidermoid carcinoma arising in Warthin's tumor of the parotid gland. Pathol. Int.. 2002.10; 52 (10): 653-656. ( PubMed )

Yasuaki Shibata, Yoshitaka Hishikawa, Shinichi Izumi, Shuichi Fujita, Akira Yamaguchi, Takehiko Koji. Involvement of Fas/Fas ligand in the induction of apoptosis in chronic sialadenitis of minor salivary glands including Sjögren's syndrome. Hum. Cell. 2002.03; 15 (1): 52-60. ( PubMed )

L Merida, M Shigetomi, K Ihara, T Tsubone, K Ikeda, A Yamaguchi, T Sugiyama, S Kawai. Effects of vitamin D analog, 22-oxa-1,25-dihydroxyvitamin D(3), on bone reconstruction by vascularized bone allograft. Bone. 2002.02; 30 (2): 422-427. ( PubMed )

Toshihiro Sugiyama, Akira Yamaguchi, Shinya Kawai. Effects of skeletal loading on bone mass and compensation mechanism in bone: a new insight into the "mechanostat" theory. J. Bone Miner. Metab.. 2002; 20 (4): 196-200. ( PubMed, DOI )

W Liu, S Toyosawa, T Furuichi, N Kanatani, C Yoshida, Y Liu, M Himeno, S Narai, A Yamaguchi, T Komori. Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures. J. Cell Biol.. 2001.10; 155 (1): 157-166. ( PubMed, DOI )

K Kusafuka, A Yamaguchi, T Kayano, T Takemura. Immunohistochemical localization of members of the transforming growth factor (TGF)-beta superfamily in normal human salivary glands and pleomorphic adenomas. J. Oral Pathol. Med.. 2001.08; 30 (7): 413-420. ( PubMed )

S Tamura, H Kataoka, Y Matsui, Y Shionoya, K Ohno, K I Michi, K Takahashi, A Yamaguchi. The effects of transplantation of osteoblastic cells with bone morphogenetic protein (BMP)/carrier complex on bone repair. Bone. 2001.08; 29 (2): 169-175. ( PubMed )

H Takahashi, S Fujita, Y Shibata, A Yamaguchi. Adenomatoid odontogenic tumour: immunohistochemical demonstration of transferrin, ferritin and alpha-one-antitrypsin. J. Oral Pathol. Med.. 2001.04; 30 (4): 237-244. ( PubMed )

K Kusafuka, Y Hiraki, C Shukunami, A Yamaguchi, T Kayano, T Takemura. Cartilage-specific matrix protein chondromodulin-I is associated with chondroid formation in salivary pleomorphic adenomas: immunohistochemical analysis. Am. J. Pathol.. 2001.04; 158 (4): 1465-1472. ( PubMed, DOI )

K Kusafuka, A Yamaguchi, T Kayano, T Takemura. Ossification of tracheal cartilage in aged humans: a histological and immunohistochemical analysis. J. Bone Miner. Metab.. 2001; 19 (3): 168-174. ( PubMed )

H Kataoka, M Ochi, K Enomoto, A Yamaguchi. Cloning and embryonic expression patterns of the zebrafish Runt domain genes, runxa and runxb. Mech. Dev.. 2000.11; 98 (1-2): 139-143. ( PubMed )

T Yamamoto-Fukud, Y Shibata, Y Hishikawa, M Shin, A Yamaguchi, T Kobayashi, T Koji. Effects of various decalcification protocols on detection of DNA strand breaks by terminal dUTP nick end labelling. Histochem. J.. 2000.11; 32 (11): 697-702. ( PubMed )

M Enomoto-Iwamoto, T Nakamura, T Aikawa, Y Higuchi, T Yuasa, A Yamaguchi, T Nohno, S Noji, T Matsuya, K Kurisu, E Koyama, M Pacifici, M Iwamoto. Hedgehog proteins stimulate chondrogenic cell differentiation and cartilage formation. J. Bone Miner. Res.. 2000.09; 15 (9): 1659-1668. ( PubMed, DOI )

A Yamaguchi, T Komori, T Suda. Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1. Endocr. Rev.. 2000.08; 21 (4): 393-411. ( PubMed, DOI )

H Kobayashi, Y h Gao, C Ueta, A Yamaguchi, T Komori. Multilineage differentiation of Cbfa1-deficient calvarial cells in vitro. Biochem. Biophys. Res. Commun.. 2000.07; 273 (2): 630-636. ( PubMed, DOI )

S Ikeda, R Hachisu, A Yamaguchi, Y H Gao, T Okano. Radiation retards muscle differentiation but does not affect osteoblastic differentiation induced by bone morphogenetic protein-2 in C2C12 myoblasts. Int. J. Radiat. Biol.. 2000.03; 76 (3): 403-411. ( PubMed )

Y Shibata, S Fujita, H Takahashi, A Yamaguchi, T Koji. Assessment of decalcifying protocols for detection of specific RNA by non-radioactive in situ hybridization in calcified tissues. Histochem. Cell Biol.. 2000.03; 113 (3): 153-159. ( PubMed )

T Tanizawa, A Yamaguchi, Y Uchiyama, C Miyaura, T Ikeda, S Ejiri, Y Nagal, H Yamato, H Murayama, M Sato, T Nakamura. Reduction in bone formation and elevated bone resorption in ovariectomized rats with special reference to acute inflammation. Bone. 2000.01; 26 (1): 43-53. ( PubMed )

Fujita S, Takahashi H, Shibata Y, Yamabe S, Yamaguchi A. A case of Hodgkin's disease of submandibular lumph nodes: differential diagnosis from anaplastic large cell lymphoma by immunohistochemistry. Oral Med Pathol . 2000; 5 99-103.

K Kusafuka, A Yamaguchi, T Kayano, T Takemura. Immunohistochemical localization of the bone morphogenetic protein-6 in salivary pleomorphic adenomas. Pathol. Int.. 1999.12; 49 (12): 1023-1027. ( PubMed )

T Takiguchi, M Kobayashi, C Nagashima, A Yamaguchi, T Nishihara, K Hasegawa. Effect of prostaglandin E2 on recombinant human bone morphogenetic protein-2-stimulated osteoblastic differentiation in human periodontal ligament cells. J. Periodont. Res.. 1999.10; 34 (7): 431-436. ( PubMed )

M Kobayashi, T Takiguchi, R Suzuki, A Yamaguchi, K Deguchi, M Shionome, Y Miyazawa, T Nishihara, M Nagumo, K Hasegawa. Recombinant human bone morphogenetic protein-2 stimulates osteoblastic differentiation in cells isolated from human periodontal ligament. J. Dent. Res.. 1999.10; 78 (10): 1624-1633. ( PubMed )

E Otsuka, A Yamaguchi, S Hirose, H Hagiwara. Characterization of osteoblastic differentiation of stromal cell line ST2 that is induced by ascorbic acid. Am. J. Physiol.. 1999.07; 277 (1 Pt 1): C132-C138. ( PubMed )

M Takagi, T Yamada, N Kamiya, T Kumagai, A Yamaguchi. Effects of bone morphogenetic protein-2 and transforming growth factor-beta1 on gene expression of decorin and biglycan by cultured osteoblastic cells. Histochem. J.. 1999.06; 31 (6): 403-409. ( PubMed )

M Yamazaki, T Shirota, Y Tokugawa, M Motohashi, K Ohno, K Michi, A Yamaguchi. Bone reactions to titanium screw implants in ovariectomized animals. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999.04; 87 (4): 411-418. ( PubMed )

H Harada, S Tagashira, M Fujiwara, S Ogawa, T Katsumata, A Yamaguchi, T Komori, M Nakatsuka. Cbfa1 isoforms exert functional differences in osteoblast differentiation. J. Biol. Chem.. 1999.03; 274 (11): 6972-6978. ( PubMed )

M Motohashi, T Shirota, Y Tokugawa, K Ohno, K Michi, A Yamaguchi. Bone reactions around hydroxyapatite-coated implants in ovariectomized rats. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999.02; 87 (2): 145-152. ( PubMed )

K Kusafuka, A Yamaguchi, T Kayano, T Takemura. Expression of bone matrix proteins, osteonectin and osteopontin, in salivary pleomorphic adenomas. Pathol. Res. Pract.. 1999; 195 (11): 733-739. ( PubMed, DOI )

Y H Gao, T Shinki, T Yuasa, H Kataoka-Enomoto, T Komori, T Suda, A Yamaguchi. Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: regulation of mRNA expression of osteoclast differentiation factor (ODF). Biochem. Biophys. Res. Commun.. 1998.11; 252 (3): 697-702. ( PubMed, DOI )

T Takiguchi, M Kobayashi, R Suzuki, A Yamaguchi, K Isatsu, T Nishihara, M Nagumo, K Hasegawa. Recombinant human bone morphogenetic protein-2 stimulates osteoblast differentiation and suppresses matrix metalloproteinase-1 production in human bone cells isolated from mandibulae. J. Periodont. Res.. 1998.11; 33 (8): 476-485. ( PubMed )

Y Suzuki, A Yamaguchi, T Ikeda, T Kawase, S Saito, Y Mikuni-Takagaki. In situ phosphorylation of bone and dentin proteins by the casein kinase II-like enzyme. J. Dent. Res.. 1998.10; 77 (10): 1799-1806. ( PubMed )

Y Hiruma, A Inoue, A Shiohama, E Otsuka, S Hirose, A Yamaguchi, H Hagiwara. Endothelins inhibit the mineralization of osteoblastic MC3T3-E1 cells through the A-type endothelin receptor. Am. J. Physiol.. 1998.10; 275 (4 Pt 2): R1099-R1105. ( PubMed )

K Kawasaki, M Aihara, J Honmo, S Sakurai, Y Fujimaki, K Sakamoto, E Fujimaki, J M Wozney, A Yamaguchi. Effects of recombinant human bone morphogenetic protein-2 on differentiation of cells isolated from human bone, muscle, and skin. Bone. 1998.09; 23 (3): 223-231. ( PubMed )

K Kusafuka, A Yamaguchi, T Kayano, T Takemura. Immunohistochemical localization of fibroblast growth factors (FGFs) and FGF receptor-1 in human normal salivary glands and pleomorphic adenomas. J. Oral Pathol. Med.. 1998.08; 27 (7): 287-292. ( PubMed )

E Otsuka, K Hirano, S Matsushita, A Inoue, S Hirose, A Yamaguchi, H Hagiwara. Effects of nitric oxide from exogenous nitric oxide donors on osteoblastic metabolism. Eur. J. Pharmacol.. 1998.05; 349 (2-3): 345-350. ( PubMed )

Y Wada, H Kataoka, S Yokose, T Ishizuya, K Miyazono, Y H Gao, Y Shibasaki, A Yamaguchi. Changes in osteoblast phenotype during differentiation of enzymatically isolated rat calvaria cells. Bone. 1998.05; 22 (5): 479-485. ( PubMed )

S Nishida, N Okimoto, Y Okazaki, A Yamaguchi, M Kumegawa, K Yasukawa, K Murayama, T Nakamura. Effect of monoclonal anti-human gp130 antibody (GPX7) on bone turnover in normal and ovariectomized rats. Calcif. Tissue Int.. 1998.03; 62 (3): 227-236. ( PubMed )

K Kusafuka, A Yamaguchi, T Kayano, M Fujiwara, T Takemura. Expression of bone morphogenetic proteins in salivary pleomorphic adenomas. Virchows Arch.. 1998.03; 432 (3): 247-253. ( PubMed )

H Hagiwara, Y Hiruma, A Inoue, A Yamaguchi, S Hirose. Deceleration by angiotensin II of the differentiation and bone formation of rat calvarial osteoblastic cells. J. Endocrinol.. 1998.03; 156 (3): 543-550. ( PubMed )

T Hanazawa, Y Kimura, H Sakamaki, A Yamaguchi, M Nagumo, T Okano. Burkitt's lymphoma involving the mandible: report of a case and review of Japanese cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998.02; 85 (2): 216-220. ( PubMed )

K Kawasaki, Y H Gao, S Yokose, Y Kaji, T Nakamura, T Suda, K Yoshida, T Taga, T Kishimoto, H Kataoka, T Yuasa, H Norimatsu, A Yamaguchi. Osteoclasts are present in gp130-deficient mice. Endocrinology. 1997.11; 138 (11): 4959-4965. ( PubMed, DOI )

T Nakamura, T Aikawa, M Iwamoto-Enomoto, M Iwamoto, Y Higuchi, M Pacifici, N Kinto, A Yamaguchi, S Noji, K Kurisu, T Matsuya, P Maurizio. Induction of osteogenic differentiation by hedgehog proteins. Biochem. Biophys. Res. Commun.. 1997.08; 237 (2): 465-469. ( PubMed )

Y H Gao, L J Yang, A Yamaguchi. Immunohistochemical demonstration of bone morphogenetic protein in odontogenic tumors. J. Oral Pathol. Med.. 1997.07; 26 (6): 273-277. ( PubMed )

T Ishizuya, S Yokose, M Hori, T Noda, T Suda, S Yoshiki, A Yamaguchi. Parathyroid hormone exerts disparate effects on osteoblast differentiation depending on exposure time in rat osteoblastic cells. J. Clin. Invest.. 1997.06; 99 (12): 2961-2970. ( PubMed, DOI )

T Komori, H Yagi, S Nomura, A Yamaguchi, K Sasaki, K Deguchi, Y Shimizu, R T Bronson, Y H Gao, M Inada, M Sato, R Okamoto, Y Kitamura, S Yoshiki, T Kishimoto. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell. 1997.05; 89 (5): 755-764. ( PubMed )

T Natsume, S Tomita, S Iemura, N Kinto, A Yamaguchi, N Ueno. Interaction between soluble type I receptor for bone morphogenetic protein and bone morphogenetic protein-4. J. Biol. Chem.. 1997.04; 272 (17): 11535-11540. ( PubMed )

N Kinto, M Iwamoto, M Enomoto-Iwamoto, S Noji, H Ohuchi, H Yoshioka, H Kataoka, Y Wada, G Yuhao, H E Takahashi, S Yoshiki, A Yamaguchi. Fibroblasts expressing Sonic hedgehog induce osteoblast differentiation and ectopic bone formation. FEBS Lett.. 1997.03; 404 (2-3): 319-323. ( PubMed )

A Dare, R Hachisu, A Yamaguchi, S Yokose, S Yoshiki, T Okano. Effects of ionizing radiation on proliferation and differentiation of osteoblast-like cells. J. Dent. Res.. 1997.02; 76 (2): 658-664. ( PubMed )

T Katagiri, S Akiyama, M Namiki, M Komaki, A Yamaguchi, V Rosen, J M Wozney, A Fujisawa-Sehara, T Suda. Bone morphogenetic protein-2 inhibits terminal differentiation of myogenic cells by suppressing the transcriptional activity of MyoD and myogenin. Exp. Cell Res.. 1997.02; 230 (2): 342-351. ( PubMed, DOI )

Y Isogai, T Akatsu, T Ishizuya, A Yamaguchi, M Hori, N Takahashi, T Suda. Parathyroid hormone regulates osteoblast differentiation positively or negatively depending on the differentiation stages. J. Bone Miner. Res.. 1996.10; 11 (10): 1384-1393. ( PubMed, DOI )

H Nishitoh, H Ichijo, M Kimura, T Matsumoto, F Makishima, A Yamaguchi, H Yamashita, S Enomoto, K Miyazono. Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5. J. Biol. Chem.. 1996.08; 271 (35): 21345-21352. ( PubMed )

T Ikeda, H Takahashi, A Suzuki, N Ueno, S Yokose, A Yamaguchi, S Yoshiki. Cloning of rat type I receptor cDNA for bone morphogenetic protein-2 and bone morphogenetic protein-4, and the localization compared with that of the ligands. Dev. Dyn.. 1996.07; 206 (3): 318-329. ( PubMed, DOI )

T Ikeda, A Yamaguchi, S Yokose, Y Nagai, H Yamato, T Nakamura, H Tsurukami, T Tanizawa, S Yoshiki. Changes in biological activity of bone cells in ovariectomized rats revealed by in situ hybridization. J. Bone Miner. Res.. 1996.06; 11 (6): 780-788. ( PubMed, DOI )

H Hagiwara, A Inoue, A Yamaguchi, S Yokose, M Furuya, S Tanaka, S Hirose. cGMP produced in response to ANP and CNP regulates proliferation and differentiation of osteoblastic cells. Am. J. Physiol.. 1996.05; 270 (5 Pt 1): C1311-C1318. ( PubMed )

M Inada, T Katagiri, S Akiyama, M Namika, M Komaki, A Yamaguchi, K Kamoi, V Rosen, T Suda. Bone morphogenetic protein-12 and -13 inhibit terminal differentiation of myoblasts, but do not induce their differentiation into osteoblasts. Biochem. Biophys. Res. Commun.. 1996.05; 222 (2): 317-322. ( PubMed )

A Inoue, Y Hiruma, S Hirose, A Yamaguchi, M Furuya, S Tanaka, H Hagiwara. Stimulation by C-type natriuretic peptide of the differentiation of clonal osteoblastic MC3T3-E1 cells. Biochem. Biophys. Res. Commun.. 1996.04; 221 (3): 703-707. ( PubMed, DOI )

A Yamaguchi, T Ishizuya, N Kintou, Y Wada, T Katagiri, J M Wozney, V Rosen, S Yoshiki. Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow-derived stromal cell lines, ST2 and MC3T3-G2/PA6. Biochem. Biophys. Res. Commun.. 1996.03; 220 (2): 366-371. ( PubMed, DOI )

Y Michiwaki, K Michi, A Yamaguchi. Marked enlargement of the jaws in secondary hyperparathyroidism--a case report. Int J Oral Maxillofac Surg. 1996.02; 25 (1): 54-56. ( PubMed )

S Yokose, T Ishizuya, T Ikeda, T Nakamura, H Tsurukami, K Kawasaki, T Suda, S Yoshiki, A Yamaguchi. An estrogen deficiency caused by ovariectomy increases plasma levels of systemic factors that stimulate proliferation and differentiation of osteoblasts in rats. Endocrinology. 1996.02; 137 (2): 469-478. ( PubMed, DOI )

S Kotake, K Sato, K J Kim, N Takahashi, N Udagawa, I Nakamura, A Yamaguchi, T Kishimoto, T Suda, S Kashiwazaki. Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation. J. Bone Miner. Res.. 1996.01; 11 (1): 88-95. ( PubMed, DOI )

Y Suzuki, T Kubota, T Koizumi, M Satoyoshi, T Teranaka, T Kawase, T Ikeda, A Yamaguchi, S Saito, Y Mikuni-Takagaki. Extracellular processing of bone and dentin proteins in matrix mineralization. Connect. Tissue Res.. 1996; 35 (1-4): 223-229. ( PubMed )

A Inoue, Y Hiruma, S Hirose, A Yamaguchi, H Hagiwara. Reciprocal regulation by cyclic nucleotides of the differentiation of rat osteoblast-like cells and mineralization of nodules. Biochem. Biophys. Res. Commun.. 1995.10; 215 (3): 1104-1110. ( PubMed, DOI )

K Iida, T Shinki, A Yamaguchi, H F DeLuca, K Kurokawa, T Suda. A possible role of vitamin D receptors in regulating vitamin D activation in the kidney. Proc. Natl. Acad. Sci. U.S.A.. 1995.06; 92 (13): 6112-6116. ( PubMed )

A Yamaguchi. Regulation of differentiation pathway of skeletal mesenchymal cells in cell lines by transforming growth factor-beta superfamily. Semin. Cell Biol.. 1995.06; 6 (3): 165-173. ( PubMed )

K Kawashima, A Yamaguchi, T Shinki, S Noji, S Yokose, T Yamaai, H Endo, S Yoshiki, E Abe, T Suda. Microgravity generated by space flight has little effect on the growth and development of chick embryonic bone. Biol. Sci. Space. 1995.06; 9 (2): 82-94. ( PubMed )

T Ikeda, Y Nagai, A Yamaguchi, S Yokose, S Yoshiki. Age-related reduction in bone matrix protein mRNA expression in rat bone tissues: application of histomorphometry to in situ hybridization. Bone. 1995.01; 16 (1): 17-23. ( PubMed )

T Katagiri, A Yamaguchi, M Komaki, E Abe, N Takahashi, T Ikeda, V Rosen, J M Wozney, A Fujisawa-Sehara, T Suda. Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J. Cell Biol.. 1994.12; 127 (6 Pt 1): 1755-1766. ( PubMed )

K Hirakawa, S Hirota, T Ikeda, A Yamaguchi, T Takemura, J Nagoshi, S Yoshiki, T Suda, Y Kitamura, S Nomura. Localization of the mRNA for bone matrix proteins during fracture healing as determined by in situ hybridization. J. Bone Miner. Res.. 1994.10; 9 (10): 1551-1557. ( PubMed, DOI )

A Dare, A Yamaguchi, S Yoshiki, T Okano. Limitation of panoramic radiography in diagnosing adenomatoid odontogenic tumors. Oral Surg. Oral Med. Oral Pathol.. 1994.06; 77 (6): 662-668. ( PubMed )

T Suda, E Abe, T Shinki, T Katagiri, A Yamaguchi, S Yokose, S Yoshiki, H Horikawa, G W Cohen, S Yasugi. The role of gravity in chick embryogenesis. FEBS Lett.. 1994.02; 340 (1-2): 34-38. ( PubMed )

Yamaguchi S, Kakuta S, Nagumo M, and Yamaguchi A. Central neurilemmoma of the mandible with rapid growth:report of a case. J Showa Univ Dent Soc . 1994; 14 228-232.

S Nishida, A Yamaguchi, T Tanizawa, N Endo, T Mashiba, Y Uchiyama, T Suda, S Yoshiki, H E Takahashi. Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells in bone marrow. Bone. 1994; 15 (6): 717-723. ( PubMed )

A Yamaguchi, A J Kahn. Monoclonal antibodies that recognize antigens in human osteosarcoma cells and normal fetal osteoblasts. Bone Miner. 1993.09; 22 (3): 165-176. ( PubMed )

Mori H, Kakuta S, Yamaguchi A, Nagumo M. Solitary intraosseous nuerofibroma of the maxilla. Report of a case. J. Oral Maxillofac. Surg. 1993; 51 688-690.

24. Yamaguchi A, Yoshiki S. Isolation and characterization of novel clonal huma osteosarcoma cell lines. Dentistry in Japan . 1993; 30 22-27.

横瀬敏志、池田通、吉木周作、山口　朗. 骨芽細胞 細胞. 1993; 25 129-133.

T Akatsu, T Tamura, N Takahashi, N Udagawa, S Tanaka, T Sasaki, A Yamaguchi, N Nagata, T Suda. Preparation and characterization of a mouse osteoclast-like multinucleated cell population. J. Bone Miner. Res.. 1992.11; 7 (11): 1297-1306. ( PubMed, DOI )

C H Jin, T Shinki, M H Hong, T Sato, A Yamaguchi, T Ikeda, S Yoshiki, E Abe, T Suda. 1 alpha,25-dihydroxyvitamin D3 regulates in vivo production of the third component of complement (C3) in bone. Endocrinology. 1992.11; 131 (5): 2468-2475. ( PubMed, DOI )

T Ikeda, S Nomura, A Yamaguchi, T Suda, S Yoshiki. In situ hybridization of bone matrix proteins in undecalcified adult rat bone sections. J. Histochem. Cytochem.. 1992.08; 40 (8): 1079-1088. ( PubMed )

Y Nakamura, A Yamaguchi, T Ikeda, S Yoshiki. Acid phosphatase activity is detected preferentially in the osteoclastic lineage by pre-treatment with cyanuric chloride. J. Histochem. Cytochem.. 1991.10; 39 (10): 1415-1420. ( PubMed )

A Yamaguchi, A J Kahn. Clonal osteogenic cell lines express myogenic and adipocytic developmental potential. Calcif. Tissue Int.. 1991.09; 49 (3): 221-225. ( PubMed )

T Ikeda, A Yamaguchi, T Icho, N Tsuchida, S Yoshiki. cDNA and deduced amino acid sequence of mouse matrix gla protein: one of five glutamic acid residues potentially modified to gla is not conserved in the mouse sequence. J. Bone Miner. Res.. 1991.09; 6 (9): 1013-1017. ( PubMed, DOI )

A Yamaguchi, T Katagiri, T Ikeda, J M Wozney, V Rosen, E A Wang, A J Kahn, T Suda, S Yoshiki. Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro. J. Cell Biol.. 1991.05; 113 (3): 681-687. ( PubMed )

T Akatsu, N Takahashi, N Udagawa, K Imamura, A Yamaguchi, K Sato, N Nagata, T Suda. Role of prostaglandins in interleukin-1-induced bone resorption in mice in vitro. J. Bone Miner. Res.. 1991.02; 6 (2): 183-189. ( PubMed, DOI )

片桐　岳信,山口　朗,須田　立雄. 骨芽細胞の分化 最新医学. 1991; 46 206-212.

Shinki T, Tanaka H, Takito J, Yamaguchi A, Nakamura Y, Yoshiki S, Suda T. Putrescine is involved in the maintenance of the intestinal villus length and the calcium absorption in the chick. Gastroentero . 1991; 100 113-122.

Y Ishimi, C Miyaura, C H Jin, T Akatsu, E Abe, Y Nakamura, A Yamaguchi, S Yoshiki, T Matsuda, T Hirano. IL-6 is produced by osteoblasts and induces bone resorption. J. Immunol.. 1990.11; 145 (10): 3297-3303. ( PubMed )

T Katagiri, A Yamaguchi, T Ikeda, S Yoshiki, J M Wozney, V Rosen, E A Wang, H Tanaka, S Omura, T Suda. The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2. Biochem. Biophys. Res. Commun.. 1990.10; 172 (1): 295-299. ( PubMed )

N Udagawa, N Takahashi, T Akatsu, T Sasaki, A Yamaguchi, H Kodama, T J Martin, T Suda. The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells. Endocrinology. 1989.10; 125 (4): 1805-1813. ( PubMed, DOI )

N Takahashi, T Akatsu, N Udagawa, T Sasaki, A Yamaguchi, J M Moseley, T J Martin, T Suda. Osteoblastic cells are involved in osteoclast formation. Endocrinology. 1988.11; 123 (5): 2600-2602. ( PubMed, DOI )

Kakuta S, Ohshima O, Yagami K, Kimura Y, Nagumo M, and Yamaguchi A. Characterization of the matrix vesicles isolated from a malignant chondroblastic tumor. J Bone Miner Metab. 1987; 5 57-63.

A Yamaguchi, Y Kohno, T Yamazaki, N Takahashi, T Shinki, N Horiuchi, T Suda, H Koizumi, Y Tanioka, S Yoshiki. Bone in the marmoset: a resemblance to vitamin D-dependent rickets, type II. Calcif. Tissue Int.. 1986.07; 39 (1): 22-27. ( PubMed )

Y Shiina, A Yamaguchi, H Yamana, E Abe, S Yoshiki, T Suda. Comparison of the mechanisms of bone resorption induced by 1 alpha,25-dihydroxyvitamin D3 and lipopolysaccharides. Calcif. Tissue Int.. 1986.07; 39 (1): 28-34. ( PubMed )

S Suda, N Takahashi, T Shinki, N Horiuchi, A Yamaguchi, S Yoshiki, S Enomoto, T Suda. 1 alpha,25-dihydroxyvitamin D3 receptors and their action in embryonic chick chondrocytes. Calcif. Tissue Int.. 1985.01; 37 (1): 82-90. ( PubMed )

T Sasaki, A Yamaguchi, S Higashi, S Yoshiki. Uptake of horseradish peroxidase by bone cells during endochondral bone development. Cell Tissue Res.. 1985; 239 (3): 547-553. ( PubMed )

Yamaguchi A, Yamanouchi M, Yoshiki S. Osteoblastic and osteoclastic differentiation of mononuclear cells facing the resorbing surface of embryonic chick. Cell Tissue Res. . 1985; 240 425-431.

Sasaki T, Yamaguchi A, Higashi S, Yoshiki S. Uptake of horseradish peroxidase by bone cells during endochondral bone development. Cell Tissue Res.. 1985; 239 547-553.

N Takahashi, T Shinki, E Abe, N Horiuchi, A Yamaguchi, S Yoshiki, T Suda. The role of vitamin D in the medullary bone formation in egg-laying Japanese quail and in immature male chicks treated with sex hormones. Calcif. Tissue Int.. 1983.07; 35 (4-5): 465-471. ( PubMed )

A Yamaguchi, M Nasu, Y Esaki, H Shimada, S Yoshiki. Amyloid deposits in the aged tongue: a postmortem study of 107 individuals over 60 years of age. J. Oral Pathol.. 1982.06; 11 (3): 237-244. ( PubMed )

山口朗、小守昭、神山隆一、石川梧朗. 左頬部に初発症状を呈した悪性組織球症の一剖検例 日本口腔科学会雑誌 . 1982; 31 149-154.

A Yamaguchi, J M Kokubu, M Takagi, G Ishikawa. Calcifying epithelial odontogenic tumor: histochemical and electron microscopic observations on a case. Bull. Tokyo Med. Dent. Univ.. 1980.09; 27 (3): 129-135. ( PubMed )

A Yamaguchi. Hyaline bodies of odontogenic cysts: histological, histochemical and electron microscopic studies. J. Oral Pathol.. 1980.07; 9 (4): 221-234. ( PubMed )

Yamaguchi A. Histopathological characteristics of bisphosphonate-related osteomyelitis (osteonecrosis) of jaw. 5th Meeting of Asian Society of Oral and Maxillofacial Pathology. 2011.08.24 福岡

Yamaguchi A. Molecular mechanism of bone destruction by oral squamous cells carcinoma. The First international Oral Pathology Update Symposium 2011.03.27 台北

Yamaguchi A. Molecular mechanism of bone destruction by oral squamous cell carcinoma. International symposium on oral cancers, systemic diseases and bone. . International symposium on oral cancers, systemic diseases and bone. 2010.03 高雄

Yamaguchi A. Role of Notch Signaling in Bone Formation.. The 26th Naito Conference on Osteobiology. 2009.11.05 淡路

Yamaguchi A. Role of BMP and Notch signaling in osteoblast differentiation and bone regeneration.. 5th Meeting of Bone Biology Forum 2008.08.23 御殿場

Yamaguchi A. Molecular mechanism of bone formation and regeneration.. 12th International Congress on Oral Cancer in conjunction with 24th International College for Maxillo-Facial Surgery. 2008.05.23 上海

Yamaguchi A. Regulation of osteoblast differentiation by BMP and Notch signaling.. 2008 International Osteoporosis Expert Meeting 2008.02.16 仁川

Yamaguchi A. Molecular basis of bone regeneration and its application.. The 12th Symposium “Recent Advancement of Dental Implant Treatment:Fusion with Regenerative Medicine”. 21st Century Center of Excellence (COE) Program for “Frontier Research Program on Molecular Destruction and Reconstruction of Tooth and Bone” 2008.01.20 東京

Yamaguchi A. Molecular basis of osteoblast differentiation and bone regeneration.. The 15th International Rheumatology Symposium. 2006.04.25 長崎

Yamaguchi A. Roles of Runx2 and BMP in osteoblast differentiation and bone regeneration. . Kyushu University Faculty of Dentistry International symposium on craniofacial development and regeneration. 2006.03.16 福岡

Yamaguchi A. Molecular basis of bone regeneration and its application to development of cell-mediated therapy for bone repair. . Tissue engineering in dental field: from bench to clinic. 2006.03.02 東京

Yamaguchi A. Role of BMP in osteoblast differentiation and bone regeneration.. The seventh international symposium on advanced bone and joint science. 2006.02.27 東京

Yamaguchi A. Does skeletons play an important role in calcium reservoir in frogs? . The 14th International Rheumatology Symposium 2005.04.18 横浜

Yamaguchi A. Skeletogemesis of frog long bones. What are similar to mammals? What are different from mammals?. The 3rd Bone Frontiers Seminar 2003.02.21 熱海

Yamaguchi A. Characteristic of skeletal formation in amphibian.. Guy’s Hospital Seminar 2002.04.05 ロンドン

Yamaguchi A. Establishment and characterization of human mesenchymal stem cells isolated from a spinal hamartoma.. Baylar Seminar 2002.02.08

Yamaguchi A. Regulatory mechanism of osteoblast differentiation. . The 10th International Rheumatology Symposium in Tokyo 2001.09.23 東京

Yamaguchi A, Gao Y-H, Komori T. Regulation of osteoblast 　differentiation by Cbfa1.. The joint international meeting of the Japanese Association for Animal Cell Technology and the European Society for Animal Cell Technology. 1998.07.27 京都

Yamaguchi A. Regulation of osteoblast differentiation by sonic hedgehog and Cbfa1.. 1998 Korean Academy of Oral Biology Symposium- The biology of osteoinductive factors and its clinical application-. 1998.06.12 ソウル

Yamaguchi A. The role of BMP-2 in the differentiation process of skeletal mesenchymal cells.. Biological mechanism of tooth movement and craniofacial adaptation 1995.10.25 ボストン

Yamaguchi A. The role of BMPs in differentiation process of skeletal mesenchymal cells. . The international Conference on Hormone and Cytokine in Bone 1995.09.25 大阪

Yamaguchi A. Regulation of differentiation pathway of skeletal mesenchymal cells by bone morphogenetic protein. . The 33rd National Institutes of Basic Biology Conference 「Mechanism of cell commitment in differentiation」 1995.03.22 岡崎

Yamaguchi A. Role of BMP in differentiation process of osteoblasts, chondrocytes and muscle cells.. The 1st China-Japan Oral Biology Conference 1994.09.28 西安

Yamaguchi A. BMP-2 regulates differentiation pathway of mesenchymal progenitor cells into osteoblasts, chondrocytes and muscle cells. . The1st International Conference of Bone Morphogenetic Protein 1994.06.09 ボルチモア

Yamaguchi A. Bone morphogenetic protein (BMP) regulates differentiation pathway of mesenchymal progenitor cells into osteoblasts, chondrocytes and muscle cells.. The 33rd National Institutes of Basic Biology Conference 「Approaches to the cellular and molecular mechanisms of regulation」 1994.03.24 岡崎