Personnel Information

写真a

AKASHI Takumi


Job title

Associate Professor

Birth date

1963

Mail Address

akashi.path@tmd.ac.jp

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Graduating School 【 display / non-display 】

  • Tokyo Medical and Dental University, Faculty of Medicine, 1987, Graduated

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Degree 【 display / non-display 】

  • PhD, Tokyo Medical and Dental University

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Campus Career 【 display / non-display 】

  • 1900.01
    -
    2017.03
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Central Clinical Facilities， Pathology， Associate Professor
  • 2004.04
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Advanced Therapeutic Sciences， Surgical Pathology， Associate Professor
  • 2018.04
    -
    2021.09
    Tokyo Medical and Dental University， (Old Organization)Medical Hospital， Central Clinical Facilities， Pathology， Associate Professor
  • 2021.10
    -
    Now
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Integrated Facilities， Pathology， Associate Professor
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Research Areas 【 display / non-display 】

  • Human pathology

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Published Papers & Misc 【 display / non-display 】

  1. Miyauchi M, Akashi T, Furukawa A, Uchida K, Tamura T, Ando N, Kirimura S, Shintaku H, Yamamoto K, Ito T, Miura K, Kayamori K, Ariizumi Y, Asakage T, Kudo A, Tanabe M, Fujii Y, Ishibashi H, Okubo K, Murakami M, Yamada T, Takemoto A, Bae Y, Eishi Y, Ohashi K. PHOX2B is a Sensitive and Specific Marker for the Histopathological Diagnosis of Pheochromocytoma and Paraganglioma. Endocr Pathol. 2022.12; 33 (4): 506-518. ( PubMed, DOI )

  2. Shunichi Baba, Takumi Akashi, Kou Kayamori, Tomoyuki Ohuchi, Ikuko Ogawa, Nobuhisa Kubota, Keisuke Nakano, Hitoshi Nagatsuka, Hiromasa Hasegawa, Kenichi Matsuzaka, Shohei Tomii, Keisuke Uchida, Noriko Katsuta, Takahiro Sekiya, Noboru Ando, Keiko Miura, Hironori Ishibashi, Yousuke Ariizumi, Takahiro Asakage, Yasuyuki Michi, Hiroyuki Harada, Kei Sakamoto, Yoshinobu Eishi, Kenichi Okubo, Tohru Ikeda. Homeobox transcription factor engrailed homeobox 1 is a possible diagnostic marker for adenoid cystic carcinoma and polymorphous adenocarcinoma. Pathol Int. 2021.02; 71 (2): 113-123. ( PubMed, DOI )

  3. Keiko Miura, Takumi Akashi, Takeshi Namiki, Tsunekazu Hishima, Yuan Bae, Urara Sakurai, Keimei Murano, Junichi Shiraishi, Masahiro Warabi, Toru Tanizawa, Michio Tanaka, Ekapot Bhunchet, Jiro Kumagai, Shinya Ayabe, Takahiro Sekiya, Noboru Ando, Hiroshi Shintaku, Yuko Kinowaki, Shohei Tomii, Susumu Kirimura, Kou Kayamori, Kurara Yamamoto, Takashi Ito, Yoshinobu Eishi. Engrailed Homeobox 1 and Cytokeratin 19 Are Independent Diagnostic Markers of Eccrine Porocarcinoma and Distinguish It From Squamous Cell Carcinoma. Am J Clin Pathol. 2020.09; 154 (4): 499-509. ( PubMed, DOI )

  4. Keiko Miura, Takumi Akashi, Noboru Ando, Shinya Ayabe, Kou Kayamori, Takeshi Namiki, Yoshinobu Eishi. Homeobox transcriptional factor engrailed homeobox 1 is expressed specifically in normal and neoplastic sweat gland cells. Histopathology. 2018.06; 72 (7): 1199-1208. ( PubMed, DOI )

  5. Shohei Tomii, Takumi Akashi, Noboru Ando, Tomoki Tamura, Akira Sakurai, Asami Terada, Asuka Furukawa, Yoshimi Suzuki, Kou Kayamori, Kei Sakamoto, Hironori Ishibashi, Yoshinobu Eishi. Cortical Actin Alteration at the Matrix-Side Cytoplasm in Lung Adenocarcinoma Cells and Its Significance in Invasion. Pathobiology. 2016.12; 84 (4): 171-183. ( PubMed, DOI )

  6. Murakami M, Hara K, Ikeda K, Horino M, Okazaki R, Niitsu Y, Takeuchi A, Aoki J, Shiba K, Tsujimoto K, Komiya C, Nakamura Y, Kurata M, Akashi T, Fujii Y, Yamada T. Single-Nucleus Analysis Reveals Tumor Heterogeneity of Aldosterone-Producing Adenoma. Hypertension (Dallas, Tex. : 1979). 2024.02; 81 (2): 361-371. ( PubMed, DOI )

  7. Kinowaki Y, Fukumura Y, Kawade G, Sugita K, Kinowaki K, Akahoshi K, Kobayashi M, Ono H, Kudo A, Tanabe M, Akashi T, Ohashi K, Kurata M. Gene expression profiling of pancreatic neuroendocrine carcinoma and mixed neuroendocrine-non-neuroendocrine neoplasm. Gene. 2024.01; 893 147916. ( PubMed, DOI )

  8. Yin Y, Sakakibara R, Honda T, Kirimura S, Daroonpan P, Kobayashi M, Ando K, Ujiie H, Kato T, Kaga K, Mitsumura T, Nakano R, Sakashita H, Matsuge S, Ishibashi H, Akashi T, Hida Y, Morohoshi T, Azuma M, Okubo K, Miyazaki Y. High density and proximity of CD8(+) T cells to tumor cells are correlated with better response to nivolumab treatment in metastatic pleural mesothelioma. Thoracic cancer. 2023.07; 14 (20): 1991-2000. ( PubMed, DOI )

  9. Hata C, Fukawa Y, Motoi T, Kinowaki Y, Akashi T, Ohashi K, Ishikawa Y, Waseda Y, Fujii Y, Kakuta R, Ikeda S, Onishi I. A Primary Kidney Giant Cell Tumor of Soft Tissue Caused Peritoneal Dissemination, Considered to Be Malignant Transformation: A Case Report. Diagnostics (Basel, Switzerland). 2023.02; 13 (4): ( PubMed, DOI )

  10. Usui E, Kanno Y, Yonetsu T, Kinowaki Y, Akashi T, Sasano T. Multimodality Imaging of Possible Healed Plaque Erosion Pathologically Validated by Directional Coronary Atherectomy Specimens. JACC. Cardiovascular interventions. 2022.11; 15 (21): 2225-2227. ( PubMed, DOI )

  11. Kusafuka K, Sato Y, Nakatani E, Baba S, Maeda M, Yamanegi K, Ueda K, Inagaki H, Otsuki Y, Kuroda N, Suzuki K, Iwai H, Imamura Y, Itakura J, Yamanaka S, Takahashi H, Ito I, Akashi T, Daa T, Hamada M, Yasuda M, Kawata R, Yamamoto H, Tachibana Y, Fukuoka J, Muramatsu A, Arai K, Suzuki M. The implicated clinical factors for outcomes in 304 patients with salivary duct carcinoma: Multi-institutional retrospective analysis in Japan. Head & neck. 2022.06; 44 (6): 1430-1441. ( PubMed, DOI )

  12. Takashi Ito, Yoshinobu Eishi, Daisuke Kobayashi, Takumi Akashi, Morio Koike, Kenichi Ohashi. A risk stratification for nodal metastasis in T1 colorectal cancer after successful therapeutic endoscopy. Gastrointest Endosc. 2022.03; 96 (1): 131-134. ( PubMed, DOI )

  13. Onishi Iichiroh, Kirimura Susumu, Wakejima Ryo, Okubo Kenichi, Odai Tamami, Kakuta Ryota, Kano Yoshihito, Ikeda Sadakatsu, Akashi Takumi, Kitagawa Masanobu. Primary pulmonary choriocarcinoma with a genomic sequence(和訳中) Pathology International. 2022.02; 72 (2): 141-143.

  14. Yumi Mochizuki, Maiko Tsuchiya, Jun Oyama, Akane Wada, Takuma Kugimoto, Takeshi Kuroshima, Hideaki Hirai, Hirofumi Tomioka, Hiroyuki Harada, Tohru Ikeda, Takumi Akashi. Left supraclavicular (Virchow's) node metastasis detected before primary infradiaphragmatic tumor: a case series. J Med Case Rep. 2022.01; 16 (1): 33. ( PubMed, DOI )

  15. Daisuke Kobayashi, Keisuke Uchida, Asuka Furukawa, Takashi Ito, Luis Masuo Maruta, Heinrich Bender Kohnert Seidler, Aloisio Felipe-Silva, Masaki Sekine, Noboru Ando, Yuka Toyama, Yusuke Chino, Keiko Miura, Kurara Yamamoto, Takumi Akashi, Yoshinobu Eishi, Kenichi Ohashi. Immunohistochemical Differentiation between Western and East Asian Types of CagA-Positive Helicobacter pylori in Gastric Biopsy Samples Can J Gastroenterol Hepatol. 2022; 2022 1371089. ( PubMed, DOI )

  16. ティーラウォン・チャンヤーヌット , 坂本 啓, 布川 裕規, 土谷 麻衣子, 栢森 高, 明石 巧, 濱垣 美和子, 富岡 博文, 黒嶋 雄志, 森田 圭一, 原田 浩之, 池田 通. 舌癌症例にみられるヒトパピローマウイルス(HPV)感染と無関係なp16免疫染色陽性反応(Immunohistochemical Positivity for p16 Unrelated to Human Papillomavirus(HPV) Infection in Lingual Squamous Cell Carcinomas) 口腔病学会雑誌. 2021.11; 88 (2-3): 115-126. ( ichushi )

  17. Keisuke Uchida, Asuka Furukawa, Akiko Yoneyama, Haruhiko Furusawa, Daisuke Kobayashi, Takashi Ito, Kurara Yamamoto, Masaki Sekine, Keiko Miura, Takumi Akashi, Yoshinobu Eishi, Kenichi Ohashi. -Derived Circulating Immune Complexes in Sarcoidosis Patients. Microorganisms. 2021.10; 9 (11): ( PubMed, DOI )

  18. Yuko Kinowaki, Shiho Abe, Shinya Abe, Shohei Tomii, Akane Yukimori, Takumi Akashi, Masanori Tokunaga, Masanobu Kitagawa. Synovial sarcoma of the stomach: a case report and a systematic review of literature. Clin J Gastroenterol. 2021.08; 14 (4): 1020-1026. ( PubMed, DOI )

  19. Kinowaki Yuko, Abe Shiho, Abe Shinya, Tomii Shohei, Yukimori Akane, Akashi Takumi, Tokunaga Masanori, Kitagawa Masanobu. 胃原発滑膜肉腫　症例報告とシステマティックレビュー(Synovial sarcoma of the stomach: a case report and a systematic review of literature) Clinical Journal of Gastroenterology. 2021.08; 14 (4): 1020-1026. ( ichushi )

  20. Tatsuya Fukuda, Ryotaro Bouchi, Takato Takeuchi, Kikuko Amo-Shiinoki, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe, Takumi Akashi, Kazuhiro Hirayama, Toshitaka Odamaki, Miki Igarashi, Ikuo Kimura, Katsuya Tanabe, Yukio Tanizawa, Tetsuya Yamada, Yoshihiro Ogawa. Importance of Intestinal Environment and Cellular Plasticity of Islets in the Development of Postpancreatectomy Diabetes. Diabetes Care. 2021.04; 44 (4): 1002-1011. ( PubMed, DOI )

  21. Kato Shu, Shimizu Hiromichi, Tomii Shohei, Uchida Hitoshi, Kawamoto Ami, Hibiya Shuji, Motobayashi Maiko, Takenaka Kento, Fujii Toshimitsu, Saito Eiko, Nagahori Masakazu, Ohtsuka Kazuo, Negi Mariko, Akashi Takumi, Matsuyama Takatoshi, Kinugasa Yusuke, Watanabe Mamoru. Substantial Epstein-Barr virus reactivation in a case of severe refractory ulcerative colitis: a possible role in exacerbation Clinical Journal of Gastroenterology. 2021.04; 14 (2): 584-588. ( ichushi )

  22. Nobuhiro Katsukura, Sho Watanabe, Tomoaki Shirasaki, Shuji Hibiya, Yoshihito Kano, Keiichi Akahoshi, Minoru Tanabe, Susumu Kirimura, Takumi Akashi, Masanobu Kitagawa, Ryuichi Okamoto, Mamoru Watanabe, Kiichiro Tsuchiya. Intestinal phenotype is maintained by Atoh1 in the cancer region of intraductal papillary mucinous neoplasm. Cancer Sci. 2021.02; 112 (2): 932-944. ( PubMed, DOI )

  23. Baba Shunichi, Akashi Takumi, Kayamori Kou, Ohuchi Tomoyuki, Ogawa Ikuko, Kubota Nobuhisa, Nakano Keisuke, Nagatsuka Hitoshi, Hasegawa Hiromasa, Matsuzaka Kenichi, Tomii Shohei, Uchida Keisuke, Katsuta Noriko, Sekiya Takahiro, Ando Noboru, Miura Keiko, Ishibashi Hironori, Ariizumi Yousuke, Asakage Takahiro, Michi Yasuyuki, Harada Hiroyuki, Sakamoto Kei, Eishi Yoshinobu, Okubo Kenichi, Ikeda Tohru. ホメオボックス転写因子engrailed homeobox 1は腺様嚢胞癌および多形腺癌の診断マーカーの可能性がある(Homeobox transcription factor engrailed homeobox 1 is a possible diagnostic marker for adenoid cystic carcinoma and polymorphous adenocarcinoma) Pathology International. 2021.02; 71 (2): 113-123. ( ichushi )

  24. Tsugeno Yuta, Kawachi Hiroshi, Kirimura Susumu, Hirota Yuka, Shintaku Hiroshi, Ito Takashi, Kikuchi Akifumi, Ohtsuka Kazuo, Akashi Takumi, Kitagawa Masanobu. 里吉症候群患者の多発性異所性腸粘膜下腺から発生した腺癌(Adenocarcinoma arising in the multiple heterotopic submucosal glands of the intestine in a Satoyoshi syndrome patient: A case report) Pathology International. 2021.02; 71 (2): 147-154. ( ichushi )

  25. Katsukura Nobuhiro, Watanabe Sho, Shirasaki Tomoaki, Hibiya Shuji, Kano Yoshihito, Akahoshi Keiichi, Tanabe Minoru, Kirimura Susumu, Akashi Takumi, Kitagawa Masanobu, Okamoto Ryuichi, Watanabe Mamoru, Tsuchiya Kiichiro. 膵管内乳頭粘液性腫瘍の癌領域において腸の表現型がAtoh1によって維持されている(Intestinal phenotype is maintained by Atoh1 in the cancer region of intraductal papillary mutinous neoplasm) Cancer Science. 2021.02; 112 (2): 932-944. ( ichushi )

  26. Kikuko Amo-Shiinoki, Katsuya Tanabe, Yoshinobu Hoshii, Hiroto Matsui, Risa Harano, Tatsuya Fukuda, Takato Takeuchi, Ryotaro Bouchi, Tokiyo Takagi, Masayuki Hatanaka, Komei Takeda, Shigeru Okuya, Wataru Nishimura, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe, Takumi Akashi, Tetsuya Yamada, Yoshihiro Ogawa, Eiji Ikeda, Hiroaki Nagano, Yukio Tanizawa. Islet cell dedifferentiation is a pathologic mechanism of long-standing progression of type 2 diabetes. JCI Insight. 2021.01; 6 (1): ( PubMed, DOI )

  27. Yukihisa Inoue, Tsukasa Okamoto, Takayuki Honda, Yoshihisa Nukui, Takumi Akashi, Tamiko Takemura, Minoru Tozuka, Yasunari Miyazaki. Disruption in the balance between apolipoprotein A-I and mast cell chymase in chronic hypersensitivity pneumonitis. Immun Inflamm Dis. 2020.12; 8 (4): 659-671. ( PubMed, DOI )

  28. Taku Sato, Shun Ishikawa, Jumpei Asano, Hirona Yamamoto, Masayuki Fujii, Toshiro Sato, Kouhei Yamamoto, Keisuke Kitagaki, Takumi Akashi, Ryuichi Okamoto, Toshiaki Ohteki. Regulated IFN signalling preserves the stemness of intestinal stem cells by restricting differentiation into secretory-cell lineages. Nat Cell Biol. 2020.07; 22 (8): 919-926. ( PubMed, DOI )

  29. Katsumi Oishi, Takashi Ito, Daisuke Sakonishi, Keisuke Uchida, Masaki Sekine, Mariko Negi, Daisuke Kobayashi, Keiko Miura, Takumi Akashi, Yoshinobu Eishi. Cancer gland rupture as a potential risk factor for lymph node metastasis in early colorectal adenocarcinoma with deep submucosal invasion. Histopathology. 2020.03; 76 (4): 603-612. ( PubMed, DOI )

  30. Hoshino Akihiro, Tokoro Shown, Akashi Takumi, Inoue Maiko, Takagi Masatoshi, Imai Kohsuke, Kanegane Hirokazu, Muraosa Yasunori, Kamei Katsuhiko, Morio Tomohiro. ハプロタイプ一致造血幹細胞移植後の小児における播種性Fusarium症(Disseminated fusariosis in a child after haploidentical hematopoietic stem cell transplantation) Pediatrics International. 2020.03; 62 (3): 419-420. ( ichushi )

  31. Yuki Iijima, Tomoya Tateishi, Kimitake Tsuchiya, Yuki Sumi, Takumi Akashi, Yasunari Miyazaki. Pneumoconiosis Caused by Inhalation of Metallic Titanium Grindings. Intern. Med.. 2020.02; 59 (3): 425-428. ( PubMed, DOI )

  32. Iijima Yuki, Tateishi Tomoya, Tsuchiya Kimitake, Sumi Yuki, Akashi Takumi, Miyazaki Yasunari. 金属チタン研削粉の吸入により引き起こされた塵肺症(Pneumoconiosis Caused by Inhalation of Metallic Titanium Grindings) Internal Medicine. 2020.02; 59 (3): 425-428. ( ichushi )

  33. Bo Liu, Atsushi Kudo, Yuko Kinowaki, Toshiro Ogura, Kosuke Ogawa, Hiroaki Ono, Yusuke Mitsunori, Daisuke Ban, Shinji Tanaka, Takumi Akashi, Minoru Tanabe. A simple and practical index predicting the prognoses of the patients with well-differentiated pancreatic neuroendocrine neoplasms. J. Gastroenterol.. 2019.09; 54 (9): 819-828. ( PubMed, DOI )

  34. Liu Bo, Kudo Atsushi, Kinowaki Yuko, Ogura Toshiro, Ogawa Kosuke, Ono Hiroaki, Mitsunori Yusuke, Ban Daisuke, Tanaka Shinji, Akashi Takumi, Tanabe Minoru. 高分化型膵神経内分泌腫瘍患者の予後を予測する簡便で実用的な指数(A simple and practical index predicting the prognoses of the patients with well-differentiated pancreatic neuroendocrine neoplasms) Journal of Gastroenterology. 2019.09; 54 (9): 819-828. ( ichushi )

  35. Hironori Ishibashi, Chihiro Takasaki, Takumi Akashi, Kenichi Okubo. Successful excision of epithelioid hemangioendothelioma of the superior vena cava. Ann. Thorac. Surg.. 2019.08; ( PubMed, DOI )

  36. Yujiro Nakano, Takanobu Yoshimoto, Ryo Watanabe, Masanori Murakami, Tatsuya Fukuda, Kazutaka Saito, Yasuhisa Fujii, Takumi Akashi, Toshihiro Tanaka, Tetsuya Yamada, Mitsuhide Naruse, Yoshihiro Ogawa. miRNA299 involvement in CYP11B2 expression in aldosterone-producing adenoma. Eur. J. Endocrinol.. 2019.07; 181 (1): 69-78. ( PubMed, DOI )

  37. Kurara Yamamoto, Keisuke Uchida, Asuka Furukawa, Tomoki Tamura, Yuki Ishige, Mariko Negi, Daisuke Kobayashi, Takashi Ito, Tomoya Kakegawa, Akira Hebisawa, Nobuyasu Awano, Tamiko Takemura, Tomonari Amano, Takumi Akashi, Yoshinobu Eishi. Catalase expression of Propionibacterium acnes may contribute to intracellular persistence of the bacterium in sinus macrophages of lymph nodes affected by sarcoidosis. Immunol. Res.. 2019.06; 67 (2-3): 182-193. ( PubMed, DOI )

  38. Hiroshi Watanabe, Hajime Tanaka, Yasuhisa Fujii, Makoto Kodama, Takumi Akashi, Tomoyuki Fujioka, Kazunori Kubota, Yukihisa Saida, Ukihide Tateishi. A case of immunoglobulin G4-related inflammatory pseudotumor mimicking renal cell carcinoma. Abdom Radiol (NY). 2019.01; 44 (4): 1230-1236. ( PubMed, DOI )

  39. Kokoro Ozaki, Takuya Ohkubo, Tetsuo Yamada, Kotaro Yoshioka, Masahiko Ichijo, Takamasa Majima, Shunsuke Kudo, Takumi Akashi, Keiji Honda, Eisaku Ito, Mayumi Watanabe, Masaki Sekine, Miwako Hamagaki, Yoshinobu Eishi, Nobuo Sanjo, Satoru Ishibashi, Hidehiro Mizusawa, Takanori Yokota. Progressive Encephalomyelitis with Rigidity and Myoclonus Resolving after Thymectomy with Subsequent Anasarca: An Autopsy Case. Intern. Med.. 2018.12; 57 (23): 3451-3458. ( PubMed, DOI )

  40. Atsushi Kudo, Keiichi Akahoshi, Sakiko Ito, Takumi Akashi, Shu Shimada, Toshiro Ogura, Kosuke Ogawa, Hiroaki Ono, Yusuke Mitsunori, Daisuke Ban, Ukihide Tateishi, Shinji Tanaka, Minoru Tanabe. Downregulated Pancreatic Beta Cell Genes Indicate Poor Prognosis in Patients With Pancreatic Neuroendocrine Neoplasms. Ann. Surg.. 2018.07; ( PubMed, DOI )

  41. Yuki Mizuno, Atsushi Kudo, Takumi Akashi, Keiichi Akahoshi, Toshiro Ogura, Kosuke Ogawa, Hiroaki Ono, Yusuke Mitsunori, Daisuke Ban, Shinji Tanaka, Ukihide Tateishi, Minoru Tanabe. Sunitinib shrinks NET-G3 pancreatic neuroendocrine neoplasms. J. Cancer Res. Clin. Oncol.. 2018.06; 144 (6): 1155-1163. ( PubMed, DOI )

  42. G Amodini Rajakaruna, Mariko Negi, Keisuke Uchida, Masaki Sekine, Asuka Furukawa, Takashi Ito, Daisuke Kobayashi, Yoshimi Suzuki, Takumi Akashi, Makoto Umeda, Walter Meinzer, Yuichi Izumi, Yoshinobu Eishi. Localization and density of Porphyromonas gingivalis and Tannerella forsythia in gingival and subgingival granulation tissues affected by chronic or aggressive periodontitis. Sci Rep. 2018.06; 8 (1): 9507. ( PubMed, DOI )

  43. Yurie Soejima, Miho Takeuchi, Takumi Akashi, Motoji Sawabe, Toshio Fukusato. β4 and β6 Integrin Expression Is Associated with the Subclassification and Clinicopathological Features of Intrahepatic Cholangiocarcinoma. Int J Mol Sci. 2018.03; 19 (4): ( PubMed, DOI )

  44. Yae Ohata, Maiko Tsuchiya, Hideaki Hirai, Satoshi Yamaguchi, Takumi Akashi, Kei Sakamoto, Akira Yamaguchi, Tohru Ikeda, Kou Kayamori. Leukemia inhibitory factor produced by fibroblasts within tumor stroma participates in invasion of oral squamous cell carcinoma. PLoS ONE. 2018; 13 (2): e0191865. ( PubMed, DOI )

  45. Junichi Ochi, Yoshio Ohtani, Tamiko Takemura, Takumi Akashi, Tomoya Tateishi, Yasunari Miyazaki, Naohiko Inase, Yasuyuki Yoshizawa. Histological variability and consequences in chronic bird-related hypersensitivity pneumonitis. Respirology. 2017.10; 22 (7): 1350-1356. ( PubMed, DOI )

  46. Atsushi Oba, Atsushi Kudo, Keiichi Akahoshi, Mitsuhiro Kishino, Takumi Akashi, Eriko Katsuta, Yasuhito Iwao, Hiroaki Ono, Yusuke Mitsunori, Daisuke Ban, Shinji Tanaka, Yoshinobu Eishi, Ukihide Tateishi, Minoru Tanabe. A simple morphological classification to estimate the malignant potential of pancreatic neuroendocrine tumors. J. Gastroenterol.. 2017.05; ( PubMed, DOI )

  47. Emiko Yamanishi, Kazuko Hasegawa, Kyota Fujita, Shizuko Ichinose, Saburo Yagishita, Miho Murata, Kazuhiko Tagawa, Takumi Akashi, Yoshinobu Eishi, Hitoshi Okazawa. A novel form of necrosis, TRIAD, occurs in human Huntington's disease. Acta Neuropathol Commun. 2017.03; 5 (1): 19. ( PubMed, DOI )

  48. Yumi Sakakibara, Yoshimi Suzuki, Toshihide Fujie, Takumi Akashi, Tadatsune Iida, Yasunari Miyazaki, Yoshinobu Eishi, Naohiko Inase. Radiopathological Features and Identification of Mycobacterial Infections in Granulomatous Nodules Resected from the Lung. Respiration. 2017.03; 93 (4): 264-270. ( PubMed, DOI )

  49. Kiichiro Tsuchiya, Ryohei Hayashi, Keita Fukushima, Shuji Hibiya, Nobukatsu Horita, Mariko Negi, Eisaku Itoh, Takumi Akashi, Yoshinobu Eishi, Satoshi Motoya, Yoshiaki Takeuchi, Reiko Kunisaki, Ken Fukunaga, Shiro Nakamura, Naoki Yoshimura, Masakazu Takazoe, Bunei Iizuka, Yasuo Suzuki, Masakazu Nagahori, Mamoru Watanabe. CDX2 expression induced by leukocytapheresis might be associated with mucosal healing in ulcerative colitis. J. Gastroenterol. Hepatol.. 2016.11; ( PubMed, DOI )

  50. Saori R Yoshii, Akiko Kuma, Takumi Akashi, Taichi Hara, Atsushi Yamamoto, Yoshitaka Kurikawa, Eisuke Itakura, Satoshi Tsukamoto, Hiroshi Shitara, Yoshinobu Eishi, Noboru Mizushima. Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons. Dev. Cell. 2016.10; 39 (1): 116-130. ( PubMed, DOI )

  51. Chihiro Takasaki, Masashi Kobayashi, Hironori Ishibashi, Takumi Akashi, Kenichi Okubo. Expression of hypoxia-inducible factor-1α affects tumor proliferation and antiapoptosis in surgically resected lung cancer. Mol Clin Oncol. 2016.08; 5 (2): 295-300. ( PubMed, DOI )

  52. Eriko Katsuta, Atsushi Kudo, Takumi Akashi, Yusuke Mitsunori, Satoshi Matsumura, Arihiro Aihara, Daisuke Ban, Takanori Ochiai, Shinji Tanaka, Yoshinobu Eishi, Minoru Tanabe. Macroscopic morphology for estimation of malignant potential in pancreatic neuroendocrine neoplasm J Cancer Res Clin Oncol . 2016.06; 142 1299-1306.

  53. Eriko Katsuta, Atsushi Kudo, Takumi Akashi, Yusuke Mitsunori, Satoshi Matsumura, Arihiro Aihara, Daisuke Ban, Takanori Ochiai, Shinji Tanaka, Yoshinobu Eishi, Minoru Tanabe. Macroscopic morphology for estimation of malignant potential in pancreatic neuroendocrine neoplasm. J. Cancer Res. Clin. Oncol.. 2016.06; 142 (6): 1299-1306. ( PubMed, DOI )

  54. Sahoko Chiba, Kimitake Tsuchiya, Takumi Akashi, Masahiro Ishizuka, Tsukasa Okamoto, Haruhiko Furusawa, Tomoya Tateishi, Mitsuhiro Kishino, Yasunari Miyazaki, Ukihide Tateishi, Tamiko Takemura, Naohiko Inase. Chronic Hypersensitivity Pneumonitis With a Usual Interstitial Pneumonia-Like Pattern: Correlation Between Histopathologic and Clinical Findings. Chest. 2016.06; 149 (6): 1473-1481. ( PubMed, DOI )

  55. Masahiro Asakawa, Takanobu Yoshimoto, Mitsutane Ota, Mitsuyuki Numasawa, Yuriko Sasahara, Takato Takeuchi, Yujiro Nakano, Norihiko Oohara, Masanori Murakami, Ryotaro Bouchi, Isao Minami, Kyoichiro Tsuchiya, Koshi Hashimoto, Hajime Izumiyama, Naoko Kawamura, Kazunori Kihara, Mariko Negi, Takumi Akashi, Yoshinobu Eishi, Hironobu Sasano, Yoshihiro Ogawa. A Case of Cushing's Syndrome with Multiple Adrenocortical Adenomas Composed of Compact Cells and Clear Cells. Endocr. Pathol.. 2016.06; 27 (2): 136-141. ( PubMed, DOI )

  56. Ryohei Hayashi, Kiichiro Tsuchiya, Keita Fukushima, Nobukatsu Horita, Shuji Hibiya, Keisuke Kitagaki, Mariko Negi, Eisaku Itoh, Takumi Akashi, Yoshinobu Eishi, Eriko Okada, Akihiro Araki, Kazuo Ohtsuka, Shinji Fukuda, Hiroshi Ohno, Ryuichi Okamoto, Tetsuya Nakamura, Shinji Tanaka, Kazuaki Chayama, Mamoru Watanabe. Reduced Human α-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn's Disease. Inflamm. Bowel Dis.. 2016.05; 22 (5): 1119-1128. ( PubMed, DOI )

  57. Teruko Nakamura, Asuka Furukawa, Keisuke Uchida, Tomohisa Ogawa, Tomoki Tamura, Daisuke Sakonishi, Yuriko Wada, Yoshimi Suzuki, Yuki Ishige, Junko Minami, Takumi Akashi, Yoshinobu Eishi. Autophagy Induced by Intracellular Infection of Propionibacterium acnes. PLoS ONE. 2016; 11 (5): e0156298. ( PubMed, DOI )

  58. Kou Kayamori, Ken-Ichi Katsube, Kei Sakamoto, Yoshio Ohyama, Hideaki Hirai, Akane Yukimori, Yae Ohata, Takumi Akashi, Masao Saitoh, Kiyoshi Harada, Hiroyuki Harada, Akira Yamaguchi. NOTCH3 Is Induced in Cancer-Associated Fibroblasts and Promotes Angiogenesis in Oral Squamous Cell Carcinoma. PLoS ONE. 2016; 11 (4): e0154112. ( PubMed, DOI )

  59. Keita Fukushima, Kiichiro Tsuchiya, Yoshihito Kano, Nobukatsu Horita, Shuji Hibiya, Ryohei Hayashi, Keisuke Kitagaki, Mariko Negi, Eisaku Itoh, Takumi Akashi, Yoshinobu Eishi, Shigeru Oshima, Takashi Nagaishi, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe. Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line. Cancer Sci.. 2015.08; 106 (8): 1000-1007. ( PubMed, DOI )

  60. Pariko Yorozu, Asuka Furukawa, Keisuke Uchida, Takumi Akashi, Tomoya Kakegawa, Tomohisa Ogawa, Junko Minami, Yoshimi Suzuki, Nobuyasu Awano, Haruhiko Furusawa, Yasunari Miyazaki, Naohiko Inase, Yoshinobu Eishi. Propionibacterium acnes catalase induces increased Th1 immune response in sarcoidosis patients. Respir Investig. 2015.07; 53 (4): 161-169. ( PubMed, DOI )

  61. Risa Nomura, Kentaro Miyai, Michiyo Okada, Michiko Kajiwara, Makoto Ono, Tsutomu Ogata, Iichiro Onishi, Mana Sato, Masaki Sekine, Takumi Akashi, Shuki Mizutani, Kenichi Kashimada. A 45,X/46,XY DSD (Disorder of Sexual Development) case with an extremely uneven distribution of 46,XY cells between lymphocytes and gonads. Clin Pediatr Endocrinol. 2015.01; 24 (1): 11-14. ( PubMed, DOI )

  62. Kana Minegishi, Takayasu Watanabe, Asuka Furukawa, Keisuke Uchida, Yoshimi Suzuki, Takumi Akashi, Fumito Maruyama, Ichiro Nakagawa, Yoshinobu Eishi. Genetic profiles of Propionibacterium acnes and identification of a unique transposon with novel insertion sequences in sarcoid and non-sarcoid isolates. Sci Rep. 2015; 5 9832. ( PubMed, DOI )

  63. Blair K Gage, Ali Asadi, Robert K Baker, Travis D Webber, Rennian Wang, Masayuki Itoh, Masaharu Hayashi, Rie Miyata, Takumi Akashi, Timothy J Kieffer. The Role of ARX in Human Pancreatic Endocrine Specification. PLoS ONE. 2015; 10 (12): e0144100. ( PubMed, DOI )

  64. Bae Hyeyeol, Yoshida Soichiro, Matsuoka Yoh, Nakajima Hiroshi, Ito Eisaku, Tanaka Hiroshi, Oya Miyako, Nakayama Takayuki, Takeshita Hideki, Kijima Toshiki, Ishioka Junichiro, Numao Noboru, Koga Fumitaka, Saito Kazutaka, Akashi Takumi, Fujii Yasuhisa, Kihara Kazunori. Apparent diffusion coefficient value as a biomarker reflecting morphological and biological features of prostate cancer Int Urol Nephrol. 2014.03; 46 (3): 555-561. ( PubMed, DOI )

  65. Bae Yuan, Ito Takashi, Iida Tadatsune, Uchida Keisuke, Sekine Masaki, Nakajima Yutaka, Kumagai Jiro, Yokoyama Tetsuji, Kawachi Hiroshi, Akashi Takumi, Eishi Yoshinobu. Intracellular Propionibacterium acnes infection in glandular epithelium and stromal macrophages of the prostate with or without cancer PLoS One. 2014; 9 (2): e90324. ( PubMed, DOI )

  66. Shinichi Hirooka, Takumi Akashi, Noboru Ando, Yoshimi Suzuki, Noriko Ishida, Morito Kurata, Touichirou Takizawa, Kou Kayamori, Kei Sakamoto, Naoyuki Fujiwara, Masao Kojima, Yoshinobu Eishi. Localization of the invadopodia-related proteins actinin-1 and cortactin to matrix-contact-side cytoplasm of cancer cells in surgically resected lung adenocarcinomas. Pathobiology. 2011; 78 (1): 10-23. ( PubMed, DOI )

  67. Akashi T, Takemura T, Ando N, Eishi Y, Kitagawa M, Takizawa T, Koike M, Ohtani Y, Miyazaki Y, Inase N, Yoshizawa Y. Histopathologic analysis of sixteen autopsy cases of chronic hypersensitivity pneumonitis and comparison with idiopathic pulmonary fibrosis/usual interstitial pneumonia Am J Clin Pathol. 2009; 131 405-15.

  68. Tamiko Takemura, Takumi Akashi, Yoshio Ohtani, Naohiko Inase, Yasuyuki Yoshizawa. Pathology of hypersensitivity pneumonitis. Curr Opin Pulm Med. 2008.09; 14 (5): 440-454. ( PubMed, DOI )

  69. Akashi T, Minami J, Ishige Y, Eishi Y, Takizawa T, Koike M, Yanagishita M. Basement membrane matrix modifies cytokine interactions between lung cancer cells and fibroblasts Pathobiology. 2005; 72 250-9.

  70. Akashi T, Ito E, Eishi Y, Koike M, Nakamura K, Burgeson RE. Reduced expression of laminin alpha 3 and alpha 5 chains in non-small cell lung cancers Jpn J Cancer Res. 2001; 92 293-301.

  71. Akashi T, Miyagi T, Ando N, Suzuki Y, Nemoto T, Eishi Y, Nakamura K, Shirasawa T, Osa N, Tanaka N, Burgeson RE. Synthesis of basement membrane by gastrointestinal cancer cell lines J Pathol. 1999; 187 223-8,.

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Conference Activities & Talks 【 display / non-display 】

  1. Honda Takayuki, Sakashita Hiroyuki, Masai Kyohei, Motoi Noriko, Kobayashi Masashi, Akashi Takumi, Mimaki Sachiyo, Tsuchihara Katsuya, Shiraishi Kouya, Okubo Kenichi, Watanabe Shun-ichi, Tsuta Koji, Inase Naohiko, Miyazaki Yasunari, Kohno Takashi. 病理学的通常型間質性肺炎を伴う肺腺癌患者における腫瘍変異負荷の分布度(Distribution of Tumor Mutation Burden in Lung Adenocarcinoma Patients with Pathological Usual Interstitial Pneumonia). 日本呼吸器学会誌 2019.03.01

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