Published Papers & Misc - SUZUKI Nobuharu

1. Binri Sasaki, Momo Oishi, Tomoka Aoki, Mai Hyodo, Chinami Onchi, Nanako Yamada, Hitomi Misawa, Momona Yamada, Chikako Hayashi, Kiyotoshi Sekiguchi, Keisuke Hamada, Yuji Yamada, Yamato Kikkawa, Motoyoshi Nomizu, Nobuharu Suzuki. Myelin Formation by Oligodendrocytes Is Enhanced Through Laminin-411 and Its Derived Peptide. Glia. 2025.08; 73 (8): 1692-1706. ( PubMed, DOI )

2. Momona Yamada, Binri Sasaki, Nanako Yamada, Chikako Hayashi, Kohei Tsumoto, Susana de Vega, Nobuharu Suzuki. The pericellular function of Fibulin-7 in the adhesion of oligodendrocyte lineage cells to neuronal axons during CNS myelination Biochem Biophys Res Commun. 2025.02; 748 151271. ( DOI )

3. Momona Yamada, Miho Iwase, Binri Sasaki, Nobuharu Suzuki. The molecular regulation of oligodendrocyte development and CNS myelination by ECM proteins Frontiers in Cell and Developmental Biology. 2022.09; 10 952135.

4. Chikako Hayashi, Nobuharu Suzuki, Riko Takahashi, Chihiro Akazawa. Development of type I/II oligodendrocytes regulated by teneurin-4 in the murine spinal cord. Sci Rep. 2020.05; 10 (1): 8611. ( PubMed, DOI )

5. Chikako Hayashi, Nobuharu Suzuki, Yo Mabuchi, Naomi Kikura, Yukina Hosoda, Susana de Vega, Chihiro Akazawa. The extracellular domain of teneurin-4 promotes cell adhesion for oligodendrocyte differentiation. Biochem Biophys Res Commun. 2020.02; 523 (1): 171-176. ( PubMed, DOI )

6. Nobuharu Suzuki, Mai Hyodo, Chikako Hayashi, Yo Mabuchi, Kaori Sekimoto, Chinami Onchi, Kiyotoshi Sekiguchi, Chihiro Akazawa. Laminin α2, α4, and α5 Chains Positively Regulate Migration and Survival of Oligodendrocyte Precursor Cells. Sci Rep. 2019.12; 9 (1): 19882. ( PubMed, DOI )

7. Chikako Hayashi, Nobuharu Suzuki. Heterogeneity of Oligodendrocytes and Their Precursor Cells. Adv. Exp. Med. Biol.. 2019.11; 1190 53-62. ( PubMed, DOI )

8. Yusuke Ogata, Yo Mabuchi, Kosuke Shinoda, Yuta Horiike, Mitsuru Mizuno, Koji Otabe, Eriko Grace Suto, Nobuharu Suzuki, Ichiro Sekiya, Chihiro Akazawa. Anterior cruciate ligament-derived mesenchymal stromal cells have a propensity to differentiate into the ligament lineage. Regen Ther. 2018.06; 8 20-28. ( PubMed, DOI )

9. Kana Ishii, Hidetoshi Sakurai, Nobuharu Suzuki, Yo Mabuchi, Ichiro Sekiya, Kiyotoshi Sekiguchi, Chihiro Akazawa. Recapitulation of Extracellular LAMININ Environment Maintains Stemness of Satellite Cells In Vitro. Stem Cell Reports. 2018.02; 10 (2): 568-582. ( PubMed, DOI )

10. Kana Ishii, Nobuharu Suzuki, Yo Mabuchi, Ichiro Sekiya, Chihiro Akazawa. Technical advantage of recombinant collagenase for isolation of muscle stem cells. Regen Ther. 2017.12; 7 1-7. ( PubMed, DOI )

11. Nobuharu Suzuki, Kaori Sekimoto, Chikako Hayashi, Yo Mabuchi, Tetsuya Nakamura, Chihiro Akazawa. Differentiation of Oligodendrocyte Precursor Cells from Sox10-Venus Mice to Oligodendrocytes and Astrocytes. Sci Rep. 2017.10; 7 (1): 14133. ( PubMed, DOI )

12. Eriko Grace Suto, Yo Mabuchi, Nobuharu Suzuki, Koji Suzuki, Yusuke Ogata, Miyu Taguchi, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa. Prospectively isolated mesenchymal stem/stromal cells are enriched in the CD73+ population and exhibit efficacy after transplantation Sci Rep. 2017.07; 7 (1): 4838. ( PubMed, DOI )

13. Susana de Vega, Kentaro Hozumi, Nobuharu Suzuki, Risa Nonaka, Eimi Seo, Anna Takeda, Tomoko Ikeuchi, Motoyoshi Nomizu, Yoshihiko Yamada, Eri Arikawa-Hirasawa. Identification of peptides derived from the C-terminal domain of fibulin-7 active for endothelial cell adhesion and tube formation disruption. Biopolymers. 2016.03; 106 (2): 184-195. ( PubMed, DOI )

14. Kana Ishii, Nobuharu Suzuki, Yo Mabuchi, Naoki Ito, Naomi Kikura, So-Ichiro Fukada, Hideyuki Okano, Shin'ichi Takeda, Chihiro Akazawa. Muscle Satellite Cell Protein Teneurin-4 Regulates Differentiation During Muscle Regeneration. Stem Cells. 2015.10; 33 (10): 3017-3027. ( PubMed, DOI )

15. High capacity of purified mesenchymal stem cells for cartilage regeneration 2015.04;

16. Yusuke Ogata, Yo Mabuchi, Mayu Yoshida, Eriko Grace Suto, Nobuharu Suzuki, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa. Purified Human Synovium Mesenchymal Stem Cells as a Good Resource for Cartilage Regeneration. PLoS ONE. 2015; 10 (6): e0129096. ( PubMed, DOI )

17. Nobuharu Suzuki, Chihiro Mizuniwa, Kana Ishii, Yusuke Nakagawa, Kunikazu Tsuji, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa. Teneurin-4, a transmembrane protein, is a novel regulator that suppresses chondrogenic differentiation. J Orthop Res. 2014.07; 32 (7): 915-922. ( PubMed, DOI )

18. Susana de Vega, Nobuharu Suzuki, Risa Nonaka, Takako Sasaki, Patricia Forcinito, Eri Arikawa-Hirasawa, Yoshihiko Yamada. A C-terminal fragment of fibulin-7 interacts with endothelial cells and inhibits their tube formation in culture. Arch Biochem Biophys. 2014.03; 545 148-153. ( PubMed, DOI )

19. Nobuharu Suzuki, Tadahiro Numakawa, Joshua Chou, Susana de Vega, Chihiro Mizuniwa, Kaori Sekimoto, Naoki Adachi, Hiroshi Kunugi, Eri Arikawa-Hirasawa, Yoshihiko Yamada, Chihiro Akazawa. Teneurin-4 promotes cellular protrusion formation and neurite outgrowth through focal adhesion kinase signaling. FASEB J. 2014.03; 28 (3): 1386-1397. ( PubMed, DOI )

20. Ryota Suzuki, Katsumi Miyahara, Hiroshi Murakami, Takashi Doi, Geoffrey J Lane, Yo Mabuchi, Nobuharu Suzuki, Atsuyuki Yamataka, Chihiro Akazawa. Abnormal neural crest innervation in Sox10-Venus mice with all-trans retinoic acid-induced anorectal malformations. Pediatr Surg Int. 2014.02; 30 (2): 189-195. ( PubMed, DOI )

21. Nobuharu Suzuki, Masaya Fukushi, Keisuke Kosaki, Andrew D Doyle, Susana de Vega, Keigo Yoshizaki, Chihiro Akazawa, Eri Arikawa-Hirasawa, Yoshihiko Yamada. Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS. J Neurosci. 2012.08; 32 (34): 11586-11599. ( PubMed, DOI )

22. Muneaki Ishijima, Nobuharu Suzuki, Kentaro Hozumi, Tomoya Matsunobu, Keisuke Kosaki, Haruka Kaneko, John R Hassell, Eri Arikawa-Hirasawa, Yoshihiko Yamada. Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation. Matrix Biol. 2012.05; 31 (4): 234-245. ( PubMed, DOI )

23. Nobuharu Suzuki, Kentaro Hozumi, Shunsuke Urushibata, Takashi Yoshimura, Yamato Kikkawa, Jessica D Gumerson, Daniel E Michele, Matthew P Hoffman, Yoshihiko Yamada, Motoyoshi Nomizu. Identification of alpha-dystroglycan binding sequences in the laminin alpha2 chain LG4-5 module. Matrix Biol.. 2010.03; 29 (2): 143-151. ( PubMed, DOI )

24. Kentaro Hozumi, Nobuharu Suzuki, Yoshihiko Uchiyama, Fumihiko Katagiri, Yamato Kikkawa, Motoyoshi Nomizu. Chain-specific heparin-binding sequences in the laminin alpha chain LG45 modules. Biochemistry. 2009.06; 48 (23): 5375-5381. ( PubMed, DOI )

25. Shu Takaki, Kozue Kato-Takagaki, Nobuharu Suzuki, Shinya Oishi, Yamato Kikkawa, Motoyoshi Nomizu. Cyclic peptide analogs of laminin active sequences enhance the biological activity. Adv. Exp. Med. Biol.. 2009; 611 297-298. ( PubMed )

26. Mayumi Mochizuki, Deborah Philp, Kentaro Hozumi, Nobuharu Suzuki, Yoshihiko Yamada, Hynda K Kleinman, Motoyoshi Nomizu. Angiogenic activity of syndecan-binding laminin peptide AG73 (RKRLQVQLSIRT). Arch. Biochem. Biophys.. 2007.03; 459 (2): 249-255. ( PubMed, DOI )

27. Kozue Kato-Takagaki, Nobuharu Suzuki, Fumiharu Yokoyama, Shu Takaki, Koji Umezawa, Junichi Higo, Mayumi Mochizuki, Yamato Kikkawa, Shinya Oishi, Atsushi Utani, Motoyoshi Nomizu. Cyclic peptide analysis of the biologically active loop region in the laminin alpha3 chain LG4 module demonstrates the importance of peptide conformation on biological activity. Biochemistry. 2007.02; 46 (7): 1952-1960. ( PubMed, DOI )

28. Kentaro Hozumi, Nobuharu Suzuki, Peter K Nielsen, Motoyoshi Nomizu, Yoshihiko Yamada. Laminin alpha1 chain LG4 module promotes cell attachment through syndecans and cell spreading through integrin alpha2beta1. J. Biol. Chem.. 2006.10; 281 (43): 32929-32940. ( PubMed, DOI )

29. Fumiharu Yokoyama, Nobuharu Suzuki, Yuichi Kadoya, Atsushi Utani, Hiroko Nakatsuka, Norio Nishi, Masahiro Haruki, Hynda K Kleinman, Motoyoshi Nomizu. Bifunctional peptides derived from homologous loop regions in the laminin alpha chain LG4 modules interact with both alpha 2 beta 1 integrin and syndecan-2. Biochemistry. 2005.07; 44 (28): 9581-9589. ( PubMed, DOI )

30. Naoki Ichikawa, Shingo Kasai, Nobuharu Suzuki, Norio Nishi, Shinya Oishi, Nobutaka Fujii, Yuichi Kadoya, Kozo Hatori, Yoshikuni Mizuno, Motoyoshi Nomizu, Eri Arikawa-Hirasawa. Identification of neurite outgrowth active sites on the laminin alpha4 chain G domain. Biochemistry. 2005.04; 44 (15): 5755-5762. ( PubMed, DOI )

31. Akane Kondo, Junko Inagaki, Kazuko Kobayashi, Hideo Tsukamoto, Daisuke Yamamoto, Mikiya Nakatsuka, Nobuharu Suzuki, Motoyoshi Nomizu, Satoshi Amano, Hidehiko Matsubayashi, Tatsuji Yasuda, Luis R Lopez, Yehuda Shoenfeld, Tsunehisa Makino, Eiji Matsuura. Characterization of a murine anti-laminin-1 monoclonal antibody (AK8) produced by immunization with mouse-derived laminin-1. Clin. Dev. Immunol.. 2005.03; 12 (1): 67-73. ( PubMed )

32. Nobuharu Suzuki, Fumiharu Yokoyama, Motoyoshi Nomizu. Functional sites in the laminin alpha chains. Connect. Tissue Res.. 2005; 46 (3): 142-152. ( PubMed, DOI )

33. Yutaka Momota, Nobuharu Suzuki, Yoshitoshi Kasuya, Takashi Kobayashi, Masako Mizoguchi, Fumiharu Yokoyama, Motoyoshi Nomizu, Hiroshi Shinkai, Toshiroh Iwasaki, Atsushi Utani. Laminin alpha3 LG4 module induces keratinocyte migration: involvement of matrix metalloproteinase-9. J. Recept. Signal Transduct. Res.. 2005; 25 (1): 1-17. ( PubMed, DOI )

34. Fumiharu Yokoyama, Nobuharu Suzuki, Masahiro Haruki, Norio Nishi, Shinya Oishi, Nobutaka Fujii, Atsushi Utani, Hynda K Kleinman, Motoyoshi Nomizu. Cyclic peptides from the loop region of the laminin alpha 4 chain LG4 module show enhanced biological activity over linear peptides. Biochemistry. 2004.10; 43 (42): 13590-13597. ( PubMed, DOI )

35. Hiroshi Matsuura, Yutaka Momota, Kaoru Murata, Hironori Matsushima, Nobuharu Suzuki, Motoyoshi Nomizu, Hiroshi Shinkai, Atsushi Utani. Localization of the laminin alpha4 chain in the skin and identification of a heparin-dependent cell adhesion site within the laminin alpha4 chain C-terminal LG4 module. J. Invest. Dermatol.. 2004.03; 122 (3): 614-620. ( PubMed, DOI )

36. Nobuharu Suzuki, Naoki Ichikawa, Shingo Kasai, Masanori Yamada, Norio Nishi, Hiroshi Morioka, Hironobu Yamashita, Yasuo Kitagawa, Atsushi Utani, Matthew P Hoffman, Motoyoshi Nomizu. Syndecan binding sites in the laminin alpha1 chain G domain. Biochemistry. 2003.11; 42 (43): 12625-12633. ( PubMed, DOI )

37. Nobuharu Suzuki, Hiroko Nakatsuka, Mayumi Mochizuki, Norio Nishi, Yuichi Kadoya, Atsushi Utani, Shinya Oishi, Nobutaka Fujii, Hynda K Kleinman, Motoyoshi Nomizu. Biological activities of homologous loop regions in the laminin alpha chain G domains. J. Biol. Chem.. 2003.11; 278 (46): 45697-45705. ( PubMed, DOI )

38. Atsushi Utani, Yutaka Momota, Hideharu Endo, Yoshitoshi Kasuya, Konrad Beck, Nobuharu Suzuki, Motoyoshi Nomizu, Hiroshi Shinkai. Laminin alpha 3 LG4 module induces matrix metalloproteinase-1 through mitogen-activated protein kinase signaling. J. Biol. Chem.. 2003.09; 278 (36): 34483-34490. ( PubMed, DOI )

39. Junko Inagaki, Mayumi Sugiura-Ogasawara, Motoyoshi Nomizu, Mikiya Nakatsuka, Katsuo Ikuta, Nobuharu Suzuki, Keiko Kaihara, Kazuko Kobayashi, Tatsuji Yasuda, Yehuda Shoenfeld, Koji Aoki, Eiji Matsuura. An association of IgG anti-laminin-1 autoantibodies with endometriosis in infertile patients. Hum. Reprod.. 2003.03; 18 (3): 544-549. ( PubMed )

40. Ikuko Okazaki, Nobuharu Suzuki, Norio Nishi, Atsushi Utani, Hiroshi Matsuura, Hiroshi Shinkai, Hironobu Yamashita, Yasuo Kitagawa, Motoyoshi Nomizu. Identification of biologically active sequences in the laminin alpha 4 chain G domain. J. Biol. Chem.. 2002.10; 277 (40): 37070-37078. ( PubMed, DOI )

41. Kozue Kato, Atsushi Utani, Nobuharu Suzuki, Mayumi Mochizuki, Masanori Yamada, Norio Nishi, Hiroshi Matsuura, Hiroshi Shinkai, Motoyoshi Nomizu. Identification of neurite outgrowth promoting sites on the laminin alpha 3 chain G domain. Biochemistry. 2002.09; 41 (35): 10747-10753. ( PubMed )

42. M Nomizu, F Yokoyama, N Suzuki, I Okazaki, N Nishi, M L Ponce, H K Kleinman, Y Yamamoto, S Nakagawa, T Mayumi. Identification of homologous biologically active sites on the N-terminal domain of laminin alpha chains. Biochemistry. 2001.12; 40 (50): 15310-15317. ( PubMed )