Yusuke Ogata, Yo Mabuchi, Kosuke Shinoda, Yuta Horiike, Mitsuru Mizuno, Koji Otabe, Eriko Grace Suto, Nobuharu Suzuki, Ichiro Sekiya, Chihiro Akazawa. Anterior cruciate ligament-derived mesenchymal stromal cells have a propensity to differentiate into the ligament lineage. Regen Ther. 2018.06; 8 20-28. ( PubMed, DOI )

Kana Ishii, Hidetoshi Sakurai, Nobuharu Suzuki, Yo Mabuchi, Ichiro Sekiya, Kiyotoshi Sekiguchi, Chihiro Akazawa. Recapitulation of Extracellular LAMININ Environment Maintains Stemness of Satellite Cells In Vitro. Stem Cell Reports. 2018.02; 10 (2): 568-582. ( PubMed, DOI )

Kana Ishii, Nobuharu Suzuki, Yo Mabuchi, Ichiro Sekiya, Chihiro Akazawa. Technical advantage of recombinant collagenase for isolation of muscle stem cells. Regen Ther. 2017.12; 7 1-7. ( PubMed, DOI )

Nobuharu Suzuki, Kaori Sekimoto, Chikako Hayashi, Yo Mabuchi, Tetsuya Nakamura, Chihiro Akazawa. Differentiation of Oligodendrocyte Precursor Cells from Sox10-Venus Mice to Oligodendrocytes and Astrocytes. Sci Rep. 2017.10; 7 (1): 14133. ( PubMed, DOI )

Eriko Grace Suto, Yo Mabuchi, Nobuharu Suzuki, Koji Suzuki, Yusuke Ogata, Miyu Taguchi, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa. Prospectively isolated mesenchymal stem/stromal cells are enriched in the CD73+ population and exhibit efficacy after transplantation Sci Rep. 2017.07; 7 (1): 4838. ( PubMed, DOI )

Susana de Vega, Kentaro Hozumi, Nobuharu Suzuki, Risa Nonaka, Eimi Seo, Anna Takeda, Tomoko Ikeuchi, Motoyoshi Nomizu, Yoshihiko Yamada, Eri Arikawa-Hirasawa. Identification of peptides derived from the C-terminal domain of fibulin-7 active for endothelial cell adhesion and tube formation disruption. Biopolymers. 2016.03; 106 (2): 184-195. ( PubMed, DOI )

Kana Ishii, Nobuharu Suzuki, Yo Mabuchi, Naoki Ito, Naomi Kikura, So-Ichiro Fukada, Hideyuki Okano, Shin'ichi Takeda, Chihiro Akazawa. Muscle Satellite Cell Protein Teneurin-4 Regulates Differentiation During Muscle Regeneration. Stem Cells. 2015.10; 33 (10): 3017-3027. ( PubMed, DOI )

High capacity of purified mesenchymal stem cells for cartilage regeneration 2015.04;

Yusuke Ogata, Yo Mabuchi, Mayu Yoshida, Eriko Grace Suto, Nobuharu Suzuki, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa. Purified Human Synovium Mesenchymal Stem Cells as a Good Resource for Cartilage Regeneration. PLoS ONE. 2015; 10 (6): e0129096. ( PubMed, DOI )

Nobuharu Suzuki, Chihiro Mizuniwa, Kana Ishii, Yusuke Nakagawa, Kunikazu Tsuji, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa. Teneurin-4, a transmembrane protein, is a novel regulator that suppresses chondrogenic differentiation. J Orthop Res. 2014.07; 32 (7): 915-922. ( PubMed, DOI )

Susana de Vega, Nobuharu Suzuki, Risa Nonaka, Takako Sasaki, Patricia Forcinito, Eri Arikawa-Hirasawa, Yoshihiko Yamada. A C-terminal fragment of fibulin-7 interacts with endothelial cells and inhibits their tube formation in culture. Arch Biochem Biophys. 2014.03; 545 148-153. ( PubMed, DOI )

Nobuharu Suzuki, Tadahiro Numakawa, Joshua Chou, Susana de Vega, Chihiro Mizuniwa, Kaori Sekimoto, Naoki Adachi, Hiroshi Kunugi, Eri Arikawa-Hirasawa, Yoshihiko Yamada, Chihiro Akazawa. Teneurin-4 promotes cellular protrusion formation and neurite outgrowth through focal adhesion kinase signaling. FASEB J. 2014.03; 28 (3): 1386-1397. ( PubMed, DOI )

Ryota Suzuki, Katsumi Miyahara, Hiroshi Murakami, Takashi Doi, Geoffrey J Lane, Yo Mabuchi, Nobuharu Suzuki, Atsuyuki Yamataka, Chihiro Akazawa. Abnormal neural crest innervation in Sox10-Venus mice with all-trans retinoic acid-induced anorectal malformations. Pediatr Surg Int. 2014.02; 30 (2): 189-195. ( PubMed, DOI )

Nobuharu Suzuki, Masaya Fukushi, Keisuke Kosaki, Andrew D Doyle, Susana de Vega, Keigo Yoshizaki, Chihiro Akazawa, Eri Arikawa-Hirasawa, Yoshihiko Yamada. Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS. J Neurosci. 2012.08; 32 (34): 11586-11599. ( PubMed, DOI )

Muneaki Ishijima, Nobuharu Suzuki, Kentaro Hozumi, Tomoya Matsunobu, Keisuke Kosaki, Haruka Kaneko, John R Hassell, Eri Arikawa-Hirasawa, Yoshihiko Yamada. Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation. Matrix Biol. 2012.05; 31 (4): 234-245. ( PubMed, DOI )

Nobuharu Suzuki, Kentaro Hozumi, Shunsuke Urushibata, Takashi Yoshimura, Yamato Kikkawa, Jessica D Gumerson, Daniel E Michele, Matthew P Hoffman, Yoshihiko Yamada, Motoyoshi Nomizu. Identification of alpha-dystroglycan binding sequences in the laminin alpha2 chain LG4-5 module. Matrix Biol.. 2010.03; 29 (2): 143-151. ( PubMed, DOI )

Kentaro Hozumi, Nobuharu Suzuki, Yoshihiko Uchiyama, Fumihiko Katagiri, Yamato Kikkawa, Motoyoshi Nomizu. Chain-specific heparin-binding sequences in the laminin alpha chain LG45 modules. Biochemistry. 2009.06; 48 (23): 5375-5381. ( PubMed, DOI )

Shu Takaki, Kozue Kato-Takagaki, Nobuharu Suzuki, Shinya Oishi, Yamato Kikkawa, Motoyoshi Nomizu. Cyclic peptide analogs of laminin active sequences enhance the biological activity. Adv. Exp. Med. Biol.. 2009; 611 297-298. ( PubMed )

Mayumi Mochizuki, Deborah Philp, Kentaro Hozumi, Nobuharu Suzuki, Yoshihiko Yamada, Hynda K Kleinman, Motoyoshi Nomizu. Angiogenic activity of syndecan-binding laminin peptide AG73 (RKRLQVQLSIRT). Arch. Biochem. Biophys.. 2007.03; 459 (2): 249-255. ( PubMed, DOI )

Kozue Kato-Takagaki, Nobuharu Suzuki, Fumiharu Yokoyama, Shu Takaki, Koji Umezawa, Junichi Higo, Mayumi Mochizuki, Yamato Kikkawa, Shinya Oishi, Atsushi Utani, Motoyoshi Nomizu. Cyclic peptide analysis of the biologically active loop region in the laminin alpha3 chain LG4 module demonstrates the importance of peptide conformation on biological activity. Biochemistry. 2007.02; 46 (7): 1952-1960. ( PubMed, DOI )

Kentaro Hozumi, Nobuharu Suzuki, Peter K Nielsen, Motoyoshi Nomizu, Yoshihiko Yamada. Laminin alpha1 chain LG4 module promotes cell attachment through syndecans and cell spreading through integrin alpha2beta1. J. Biol. Chem.. 2006.10; 281 (43): 32929-32940. ( PubMed, DOI )

Fumiharu Yokoyama, Nobuharu Suzuki, Yuichi Kadoya, Atsushi Utani, Hiroko Nakatsuka, Norio Nishi, Masahiro Haruki, Hynda K Kleinman, Motoyoshi Nomizu. Bifunctional peptides derived from homologous loop regions in the laminin alpha chain LG4 modules interact with both alpha 2 beta 1 integrin and syndecan-2. Biochemistry. 2005.07; 44 (28): 9581-9589. ( PubMed, DOI )

Naoki Ichikawa, Shingo Kasai, Nobuharu Suzuki, Norio Nishi, Shinya Oishi, Nobutaka Fujii, Yuichi Kadoya, Kozo Hatori, Yoshikuni Mizuno, Motoyoshi Nomizu, Eri Arikawa-Hirasawa. Identification of neurite outgrowth active sites on the laminin alpha4 chain G domain. Biochemistry. 2005.04; 44 (15): 5755-5762. ( PubMed, DOI )

Akane Kondo, Junko Inagaki, Kazuko Kobayashi, Hideo Tsukamoto, Daisuke Yamamoto, Mikiya Nakatsuka, Nobuharu Suzuki, Motoyoshi Nomizu, Satoshi Amano, Hidehiko Matsubayashi, Tatsuji Yasuda, Luis R Lopez, Yehuda Shoenfeld, Tsunehisa Makino, Eiji Matsuura. Characterization of a murine anti-laminin-1 monoclonal antibody (AK8) produced by immunization with mouse-derived laminin-1. Clin. Dev. Immunol.. 2005.03; 12 (1): 67-73. ( PubMed )

Nobuharu Suzuki, Fumiharu Yokoyama, Motoyoshi Nomizu. Functional sites in the laminin alpha chains. Connect. Tissue Res.. 2005; 46 (3): 142-152. ( PubMed, DOI )

Yutaka Momota, Nobuharu Suzuki, Yoshitoshi Kasuya, Takashi Kobayashi, Masako Mizoguchi, Fumiharu Yokoyama, Motoyoshi Nomizu, Hiroshi Shinkai, Toshiroh Iwasaki, Atsushi Utani. Laminin alpha3 LG4 module induces keratinocyte migration: involvement of matrix metalloproteinase-9. J. Recept. Signal Transduct. Res.. 2005; 25 (1): 1-17. ( PubMed, DOI )

Fumiharu Yokoyama, Nobuharu Suzuki, Masahiro Haruki, Norio Nishi, Shinya Oishi, Nobutaka Fujii, Atsushi Utani, Hynda K Kleinman, Motoyoshi Nomizu. Cyclic peptides from the loop region of the laminin alpha 4 chain LG4 module show enhanced biological activity over linear peptides. Biochemistry. 2004.10; 43 (42): 13590-13597. ( PubMed, DOI )

Hiroshi Matsuura, Yutaka Momota, Kaoru Murata, Hironori Matsushima, Nobuharu Suzuki, Motoyoshi Nomizu, Hiroshi Shinkai, Atsushi Utani. Localization of the laminin alpha4 chain in the skin and identification of a heparin-dependent cell adhesion site within the laminin alpha4 chain C-terminal LG4 module. J. Invest. Dermatol.. 2004.03; 122 (3): 614-620. ( PubMed, DOI )

Nobuharu Suzuki, Naoki Ichikawa, Shingo Kasai, Masanori Yamada, Norio Nishi, Hiroshi Morioka, Hironobu Yamashita, Yasuo Kitagawa, Atsushi Utani, Matthew P Hoffman, Motoyoshi Nomizu. Syndecan binding sites in the laminin alpha1 chain G domain. Biochemistry. 2003.11; 42 (43): 12625-12633. ( PubMed, DOI )

Nobuharu Suzuki, Hiroko Nakatsuka, Mayumi Mochizuki, Norio Nishi, Yuichi Kadoya, Atsushi Utani, Shinya Oishi, Nobutaka Fujii, Hynda K Kleinman, Motoyoshi Nomizu. Biological activities of homologous loop regions in the laminin alpha chain G domains. J. Biol. Chem.. 2003.11; 278 (46): 45697-45705. ( PubMed, DOI )

Atsushi Utani, Yutaka Momota, Hideharu Endo, Yoshitoshi Kasuya, Konrad Beck, Nobuharu Suzuki, Motoyoshi Nomizu, Hiroshi Shinkai. Laminin alpha 3 LG4 module induces matrix metalloproteinase-1 through mitogen-activated protein kinase signaling. J. Biol. Chem.. 2003.09; 278 (36): 34483-34490. ( PubMed, DOI )

Junko Inagaki, Mayumi Sugiura-Ogasawara, Motoyoshi Nomizu, Mikiya Nakatsuka, Katsuo Ikuta, Nobuharu Suzuki, Keiko Kaihara, Kazuko Kobayashi, Tatsuji Yasuda, Yehuda Shoenfeld, Koji Aoki, Eiji Matsuura. An association of IgG anti-laminin-1 autoantibodies with endometriosis in infertile patients. Hum. Reprod.. 2003.03; 18 (3): 544-549. ( PubMed )

Ikuko Okazaki, Nobuharu Suzuki, Norio Nishi, Atsushi Utani, Hiroshi Matsuura, Hiroshi Shinkai, Hironobu Yamashita, Yasuo Kitagawa, Motoyoshi Nomizu. Identification of biologically active sequences in the laminin alpha 4 chain G domain. J. Biol. Chem.. 2002.10; 277 (40): 37070-37078. ( PubMed, DOI )

Kozue Kato, Atsushi Utani, Nobuharu Suzuki, Mayumi Mochizuki, Masanori Yamada, Norio Nishi, Hiroshi Matsuura, Hiroshi Shinkai, Motoyoshi Nomizu. Identification of neurite outgrowth promoting sites on the laminin alpha 3 chain G domain. Biochemistry. 2002.09; 41 (35): 10747-10753. ( PubMed )

M Nomizu, F Yokoyama, N Suzuki, I Okazaki, N Nishi, M L Ponce, H K Kleinman, Y Yamamoto, S Nakagawa, T Mayumi. Identification of homologous biologically active sites on the N-terminal domain of laminin alpha chains. Biochemistry. 2001.12; 40 (50): 15310-15317. ( PubMed )

Mizuki Fukuhara, Yuki Munakata, Reina Ohno, Nanako Yamada, Momona Yamada, Chikako Hayashi, and Nobuharu Suzuki. Evaluation of cell adhesion activity of mutant teneurin-4 and its effect on the diseases. 第46回日本分子生物学会年会 2023.12.06

Mizuki Fukuhara, Chikako Hayashi, Yuki Munakata, Reina Ohno, Nanako Yamada, Momona Yamada, and Nobuharu Suzuki. The molecular mechanism of CNS myelination through the cell adhesion of teneurin-4 and its effect on the diseases. 第66回日本神経化学会大会 2023.07.08

Hinako Saito, Riko Takahashi, Mio Fujisato, Yukina Hosoda, Chikako Hayashi, and Nobuharu Suzuki. The molecular mechanism of axonal survival in the murine dysmyelination. 第66回日本神経化学会大会 2023.07.08

Momona Yamada, Miho Iwase, Chikako Hayashi, de Vega Susana, Nobuharu Suzuki. An extracellular matrix protein Fibulin-7 positively regulates oligodendrocyte differentiation through the N-terminal active sequence. 第45回日本分子生物学会年会 2022.12.01

Miho Iwase, Chikako Hayashi, Binri Sasaki, Momona Yamada, Nobuharu Suzuki. Teneurin-4 promotes CNS myelin formation through a molecular interaction with actin-regulating proteins in oligodendrocytes. 第45回日本分子生物学会年会 2022.11.30

Momona Yamada, Miho Iwase, Chikako Hayashi, Susana de Vega, Nobuharu Suzuki. The extracellular matrix protein fibulin-7 positively regulates oligodendrocyte differentiation through the interaction between myelin and neuronal axons. Neuroscience 2022 2022.11.13 San Diego Convention Center, San Diego, CA, USA

Miho Iwase, Chikako Hayashi, Binri Sasaki, Momona Yamada, Nobuharu Suzuki. Teneurin-4 forms a molecular complex with actin-regulating proteins in oligodendrocytes and promotes myelin sheath formation in the CNS. Neuroscience 2022 2022.11.13 San Diego Convention Center, San Diego, CA, USA

Nobuharu Suzuki, Riko Takahashi, Hinako Saito, Yukina Hosoda, Chikako Hayashi. The Maintenance of Small Caliber Axons in Teneurin-4 Deficient Mice with the Congenital Hypomyelination in the CNS. 第65回日本神経化学会大会 2022.07.02

Miho Iwase, Momona Yamada, Chikako Hayashi, Nobuharu Suzuki. The molecular function of the actin cytoskeletal regulator Arpc1a in proliferation and morphogenesis of oligodendrocyte-lineage cells. 第65回日本神経化学会大会 2022.07.01

Momona Yamada, Miho Iwase, Chikako Hayashi, Susana de Vega, Nobuharu Suzuki. Fibulin-7, an extracellular matrix protein, positively regulates oligodendrocyte differentiation and attachment to neuronal axons. 第65回日本神経化学会大会 2022.07.01

Riko Takahashi, Hinako Saito, Yukina Hosoda, Chikako Hayashi, Nobuharu Suzuki. The maintenance of unmyelinated small diameter axons in the CNS. 第44回日本分子生物学会年会 2021.12.03

Momona Yamada, Miho Iwase, Chikako Hayashi, de Vega Susana, Nobuharu Suzuki. The extracellular matrix protein Fibulin-7 relates to the cell interaction for myelination in CNS. 第44回日本分子生物学会年会 2021.12.03

Riko Takahashi, Hinako Saito, Yukina Hosoda, Chikako Hayashi, Nobuharu Suzuki. The maintenance of small diameter axons after myelination defect in the CNS. 第64回日本神経化学会大会 2021.09.30

Momona Yamada, Miho Iwase, Chikako Hayashi, de Vega Susana, Nobuharu Suzuki. The extracellular matrix protein fibulin-7 regulates cellular interaction for CNS myelination. 第64回日本神経化学会大会 2021.09.30

Miho Iwase, Momona Yamada, Chikako Hayashi, Nobuharu Suzuki. The expression pattern and functional analysis of Arpc1a controlling actin cytoskeleton at the initial stage of myelination. 第64回日本神経化学会大会 2021.09.30

Riko Takahashi, Chikako Hayashi, Miho Iwase, Nobuharu Suzuki. Teneurin-4 regulates the generation of type I/II oligodendrocytes that myelinate small diameter axons.. 第63回日本神経化学会大会 2020.09.11

Yuki Munakata, Yukina Hosoda, Hiromi Kurumada, Chikako Hayashi, Nobuharu Suzuki. The crucial role of teneurin-4 associated with actin binding protein CNP in myelination and axonal maintenance.. 第63回日本神経化学会大会 2020.09.11

Momo Ooishi, Chinami Onchi, Momona Yamada, Chikako Hayashi, Nobuharu Suzuki. Promoted oligodendrocyte precursor cell proliferation and surivival via laminin E3 fragments.. 第63回日本神経化学会大会 2020.09.10

Nobuharu Suzuki. Cell Adhesion Proteins Regulate Myelination of Small Caliber Axons Critically Involved in Myelin-related Diseases. 第63回日本神経化学会大会 2020.09.10

Chikako Hayashi, Yukina Hosoda, Chinami Onchi, Nobuharu Suzuki. Teneurin-4 positively regulates oligodendrocyte-axon adhesion and myelination through the binding with teneurins.. 12th FENS Forum of Neuroscience 2020.07.12

Nobuharu Suzuki, Chikako Hayashi, Yo Mabuchi, Naomi Kikura, Yukina Hosoda, Susana de Vega, Chihiro Akazawa. Teneurin-4 gene associated with mental disorders regulates CNS myelination through cell adhesion between oligodendrocytes and neuronal axons. The 10th Takeda Science Foundation Symposium on PharmaSciences 2020.01.24

Nobuharu Suzuki, Yoshihiko Yamada. Teneurin-4 Is a Positive Regulator of CNS Myelination through Oligodendrocyte Process Formation. XIV European Meeting on Glial Cells in Health and Disease 2019.07.11

Chikako Hayashi, Nobuharu Suzuki, Naomi Kikura, Yukina Hosoda, Yo Mabuchi, Chihiro Akazawa. Molecular Interaction between Oligodendrocytes and Axons through Teneurins for CNS Myelination. XIV European Meeting on Glial Cells in Health and Disease 2019.07.11

Chikako Hayashi, Nobuharu Suzuki, Naomi Kikura, Yukina Hosoda, Yo Mabuchi, Chihiro Akazawa. Oligodendrocyte-Axon Interaction via Teneurin-4 Controls Cell Adhesion and Morphogenesis of Oligodendrocytes for Myelination. Neuroscience 2018 2018.11.03 San Diego Convention Center, San Diego, CA, USA

Nobuharu Suzuki, Yoshihiko Yamada. Teneurin-4 regulates oligodendrocyte process formation in CNS myelination. Neuroscience 2018 2018.11.03 San Diego Convention Center, San Diego, CA, USA

Teneurin-4 is a transmembrane protein regulating cell adhesion and cytoskeletal organization in oligodendrocytes. 2017.11.14

Kaori Sekimoto, Nobuharu Suzuki, Yo Mabuchi, Chikako Hayashi, Tetsuya Nakamura, and Chihiro Akazawa.. Isolation of Sox10-Venus oligodendrocyte precursor cells differentiable to oligodendrocytes and type 2 astrocytes. 第３７回日本分子生物学会年会 2014.11.27 横浜

Eriko Grace Suto, Yo Mabuchi, Nobuharu Suzuki, Asuka Koyanagi, Yoshiko Kawabata, Nobutake Ozeki, Yusuke Nakagawa, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa. Purified Mesenchymal Stem Cells Have High Ability for differentiation in vivo.. 第３７回日本分子生物学会年会 2014.11.27 横浜

石井佳菜、鈴木喜晴、 馬渕洋、木倉直美、伊藤尚基、深田宗一郎、武田伸一、赤澤智宏. Teneurin-4 Suppresses Proliferation and Differentiation of Muscle Satellite Cells in Vitro Myogenesis. 第３７回日本分子生物学会年会 2014.11.27 横浜

緒方勇亮、馬渕洋、吉田茉由、須藤絵里子グレース、鈴木喜晴、宗田大、関矢一郎、赤澤智宏. ヒト滑膜由来間葉系幹細胞の増殖能力及び軟骨分化能力の解析」. 第３７回日本分子生物学会年会 2014.11.27 横浜

Chihiro Akazawa. The New Japanese Regulation for Regenerative Medicine. The 9th New York Stem Cell Foundation Annual Meeting 2014.10.22 New York

Eriko Grace Suto, Yo Mabuchi, Nobuharu Suzuki, Asuka Koyanagi, Yoshiko Kawabata, Takeshi Muneta, Ichiro Sekiya, and Chihiro Akazawa.. Purified Mesenchymal Stem Cells maintain purity and have high ability of chondrogenic regeneration after prolonged culture.. The 9th New York Stem Cell Foundation Annual Meeting 2014.10.22 New York

Kana Ishii, Nobuharu Suzuki, Yo Mabuchi, Naomi Kikura, Naoki Ito, Shin’ich Takeda, and Chihiro Akazawa.. Suppressive Function of Teneurin-4, a Muscle Satellite Cell Protein, in Cell Proliferation and Differentiation during Myogenesis.. The 9th New York Stem Cell Foundation Annual Meeting 2014.10.22 New York

Chihiro Akazawa. Large Scale iPSC Initiatives Arround the World. 12th Annual Meeting of ISSCR 2014.06.18 Vancouver

Susana de Vega, Eimi Seo, Anna Takeda, Nobuharu Suzuki, Risa Nonaka, Kentaro Hozumi, Motoyoshi Nomizu, Yoshihiko Yamada, and Eri Arikawa-Hirasawa. Identification of Fibulin-7 Peptides Active for Endothelial Cell Adhesion and Tube Formation. 第４６回日本結合組織学会学術大会 2014.06.06 名古屋

Kaori Sekimoto, Nobuharu Suzuki, Yo Mabuchi, and Chihiro Akazawa.. In vitro Analysis of Differentiation of Oligodendrocytes and Astrocytes Using Sox10-Venus Mice.. Experimental Biology 2014 2014.04.30 San Diego

Kana Ishii, Nobuharu Suzuki, Yo Mabuchi, and Chihiro Akazawa.. Teneurin-4 is a novel suppressor of myogenesis.. Experimental Biology 2014 2014.04.30 San Diego