論文・総説 - 伊藤　暢聡

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  1. Inaba Yuka, Nakabayashi Makoto, Itoh Toshimasa, Yoshimoto Nobuko, Ikura Teikichi, Ito Nobutoshi, Shimizu Masato, Yamamoto Keiko. 22S-butyl-1alpha,24R-dihydroxyvitamin D3: recovery of vitamin D receptor agonistic activity. J Steroid Biochem Mol Biol. 2010.07; 121 (1-2): 146-150. ( PubMed, DOI )

  2. Ogawa Yasushi, Nonaka Yosuke, Goto Toshiyasu, Ohnishi Eriko, Hiramatsu Toshiyuki, Kii Isao, Yoshida Miyo, Ikura Teikichi, Onogi Hiroshi, Shibuya Hiroshi, Hosoya Takamitsu, Ito Nobutoshi, Hagiwara Masatoshi. Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A. Nat Commun. 2010; 1 86. ( PubMed, DOI )

  3. Inaba Yuka, Yoshimoto Nobuko, Sakamaki Yuta, Nakabayashi Makoto, Ikura Teikichi, Tamamura Hirokazu, Ito Nobutoshi, Shimizu Masato, Yamamoto Keiko. A new class of vitamin D analogues that induce structural rearrangement of the ligand-binding pocket of the receptor. J Med Chem. 2009.03; 52 (5): 1438-1449. ( PubMed, DOI )

  4. Nakabayashi Makoto, Yamada Sachiko, Yoshimoto Nobuko, Tanaka Takashi, Igarashi Miharu, Ikura Teikichi, Ito Nobutoshi, Makishima Makoto, Tokiwa Hiroaki, DeLuca Hector F, Shimizu Masato. Crystal structures of rat vitamin D receptor bound to adamantyl vitamin D analogs: structural basis for vitamin D receptor antagonism and partial agonism. J Med Chem. 2008.09; 51 (17): 5320-5329. ( PubMed, DOI )

  5. Shimizu Masato, Miyamoto Yukiko, Takaku Hajime, Matsuo Mayumi, Nakabayashi Makoto, Masuno Hiroyuki, Udagawa Nobuyuki, DeLuca Hector F, Ikura Teikichi, Ito Nobutoshi. 2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure. Bioorg Med Chem. 2008.07; 16 (14): 6949-6964. ( PubMed, DOI )

  6. Urakubo Yoshiaki, Ikura Teikichi, Ito Nobutoshi. Crystal structural analysis of protein-protein interactions drastically destabilized by a single mutation. Protein Sci. 2008.06; 17 (6): 1055-1065. ( PubMed, DOI )

  7. Ikura Teikichi, Kinoshita Kengo, Ito Nobutoshi. A cavity with an appropriate size is the basis of the PPIase activity. Protein Eng Des Sel. 2008.02; 21 (2): 83-89. ( PubMed, DOI )

  8. Ikura Teikichi, Ito Nobutoshi. Requirements for peptidyl-prolyl isomerization activity: a comprehensive mutational analysis of the substrate-binding cavity of FK506-binding protein 12. Protein Sci. 2007.12; 16 (12): 2618-2625. ( PubMed, DOI )

  9. Oda Masayuki, Ito Nobutoshi, Tsumuraya Takeshi, Suzuki Kayo, Sakakura Masayoshi, Fujii Ikuo. Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis. J Mol Biol. 2007.05; 369 (1): 198-209. ( PubMed, DOI )

  10. Tsuchiya Yuko, Kinoshita Kengo, Ito Nobutoshi, Nakamura Haruki. PreBI: prediction of biological interfaces of proteins in crystals. Nucleic Acids Res. 2006.07; 34 (Web Server issue): W320-W324. ( PubMed, DOI )

  11. Westbrook John, Ito Nobutoshi, Nakamura Haruki, Henrick Kim, Berman Helen M. PDBML: the representation of archival macromolecular structure data in XML. Bioinformatics. 2005.04; 21 (7): 988-992. ( PubMed, DOI )

  12. Higo J, Ito N, Kuroda M, Ono S, Nakajima N, Nakamura H. Energy landscape of a peptide consisting of alpha-helix, 3(10)-helix, beta-turn, beta-hairpin, and other disordered conformations. Protein Sci. 2001.06; 10 (6): 1160-1171. ( PubMed, DOI )

  13. Otomo T, Ito N, Kyogoku Y, Yamazaki T. NMR observation of selected segments in a larger protein: Central-segment isotope labeling through intein-mediated ligation BIOCHEMISTRY. 1999.12; 38 (49): 16040-16044. ( DOI )

  14. Yamazaki T, Otomo T, Oda N, Kyogoku Y, Uegaki K, Ito N, Ishino Y, Nakamura H. Segmental isotope labeling for protein NMR using peptide splicing JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 1998.06; 120 (22): 5591-5592. ( DOI )

  15. ITO N, KOMIYAMA NH, FERMI G. STRUCTURE OF DEOXYHEMOGLOBIN OF THE ANTARCTIC FISH PAGOTHENIA-BERNACCHII WITH AN ANALYSIS OF THE STRUCTURAL BASIS OF THE ROOT EFFECT BY COMPARISON OF THE LIGANDED AND UNLIGANDED HEMOGLOBIN STRUCTURES JOURNAL OF MOLECULAR BIOLOGY. 1995.07; 250 (5): 648-658. ( DOI )

  16. NAGAI K, OUBRIDGE C, ITO N, AVIS J, EVANS P. THE RNP DOMAIN - A SEQUENCE-SPECIFIC RNA-BINDING DOMAIN INVOLVED IN PROCESSING AND TRANSPORT OF RNA TRENDS IN BIOCHEMICAL SCIENCES. 1995.06; 20 (6): 235-240. ( DOI )

  17. PRICE SR, ITO N, OUBRIDGE C, AVIS JM, NAGAI K. CRYSTALLIZATION OF RNA-PROTEIN COMPLEXES .1. METHODS FOR THE LARGE-SCALE PREPARATION OF RNA SUITABLE FOR CRYSTALLOGRAPHIC STUDIES JOURNAL OF MOLECULAR BIOLOGY. 1995.06; 249 (2): 398-408. ( DOI )

  18. OUBRIDGE C, ITO N, TEO CH, FEARNLEY I, NAGAI K. CRYSTALLIZATION OF RNA-PROTEIN COMPLEXES .2. THE APPLICATION OF PROTEIN ENGINEERING FOR CRYSTALLIZATION OF THE U1A PROTEIN-RNA COMPLEX JOURNAL OF MOLECULAR BIOLOGY. 1995.06; 249 (2): 409-423. ( DOI )

  19. Nagai K, Oubridge C, Ito N, Jessen T H, Avis J, Evans P. Crystal structure of the U1A spliceosomal protein complexed with its cognate RNA hairpin. Nucleic Acids Symp Ser. 1995; (34): 1-2. ( PubMed )

  20. Ito N, Knowles P F, Phillips S E. X-ray crystallographic studies of cofactors in galactose oxidase. Methods Enzymol. 1995; 258 235-262. ( PubMed )

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