Personnel Information

写真a

OSAKA Mizuko


Job title

Assistant Professor

Mail Address

mizu.vasc@tmd.ac.jp

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Graduating School 【 display / non-display 】

  • Tokyo University of Science, Faculty of Engineering Science, biological science and technology, 1994.03, Graduated

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Degree 【 display / non-display 】

  • PhD, Tokyo Medical and Dental University

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Campus Career 【 display / non-display 】

  • 2010.04
    -
    2011.03
    Tokyo Medical and Dental University， Joint Institutes for Education and Research， Life Science and Bioethics Research Center， Department of Life Sciences and Medical Ethics， Project Assistant Professor
  • 2011.04
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Public Health， Life Sciences and Bioethics， Assistant Professor
  • 2014.10
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    2017.03
    Tokyo Medical and Dental University， Research and Industry-University Alliance Organization， Life Science and Bioethics Research Center， Assistant Professor
  • 2014.10
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Endowed Departments， Department of Nutrition and Metabolism in Cardiovascular Disease， Project Assistant Professor
  • 2017.04
    　
    　
    Tokyo Medical and Dental University， Institute of Research， Research Facility Cluster， Life Science and Bioethics Research Center， Assistant Professor

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Research Areas 【 display / non-display 】

  • General medical chemistry

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Published Papers & Misc 【 display / non-display 】

  • Mizuko Osaka, Shunsuke Ito, Masaki Honda, Yukihiro Inomata, Kensuke Egashira, Masayuki Yoshida. Critical role of the C5a-activated neutrophils in high-fat diet-induced vascular inflammation. Scientific Reports. 2016.02; 6 21391. ( PubMed, DOI )

  • Inoue Reiko, Nishi Hiroshi, Osaka Mizuko, Yoshida Masayuki, Nangaku Masaomi. NEUTROPHIL INTERFERON-INDUCED, DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE (EIF2AK2) PROMOTES ADHESION IN NON-VIRAL INFLAMMATORY KIDNEY DISEASE NEPHROLOGY. 2020.10; 25 35.

  • Tsuru H, Osaka M, Hiraoka Y, Yoshida M. HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse. Scientific reports. 2020.10; 10 (1): 17593. ( PubMed, DOI )

  • Dewan Syed Masudur Rahman, Deushi Michiyo, Osaka Mizuko, Yoshida Masayuki. C5a stimulation of differentiated HL60 induces THP-1 chemotaxis via MCP-1 dependent pathway(和訳中) 日本動脈硬化学会総会プログラム・抄録集. 2020.07; 52回 268. ( ichushi )

  • Tsuru Hiromi, Osaka Mizuko, Yoshida Masayuki. Critical Role of Complement Factor D in the Development of High-fat Diet-induced Fatty Liver(和訳中) 日本循環器学会学術集会抄録集. 2020.07; 84回 PE28-2. ( ichushi )

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Conference Activities & Talks 【 display / non-display 】

  • 大坂瑞子. 動脈硬化症関連血管炎症反応における好中球でのヒストンシトルリン化の重要性. 第43回日本分子生物学会年会 2020.12.02

  • Syed Masudur Rahman Dewan, Michiyo Deushi, Mizuko Osaka, Masayuki Yoshida. C5a elevates MCP-1 expression in neutrophil-like differentiated HL60 via NF-κB signaling pathway. 第84回日本循環器学会学術集会 2020.07.27 京都

  • Hiromi Tsuru, Mizuko Osaka, Masayuki Yoshida. Critical Role of Complement Factor D in the Development of High-fat Diet-induced Fatty Liver . 第84回日本循環器学会学術集会 2020.07.27 Kyoto

  • 大坂　瑞子、出牛　三千代、吉田　雅幸. 選択的PPARaアゴニスト、ペマフィブラートはLDL受容体欠損マウス大腿動脈における高中性脂肪血症を改善し、白血球接着を抑制する. 第52回日本動脈硬化学会総会・学術集会 2020.07.17 名古屋

  • Mizuko Osaka, Masayuki Yoshida. The involvement of neutrophil extracellular traps in HFD-induced vascular inflammation in LDLR null mice. Cardiovascular and Metabolic Week 2019 2019.12.14

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