Personnel Information

写真a

MATSUMURA Hiroyuki


Job title

Assistant Professor

Birth date

1979

Graduating School 【 display / non-display

  • Kyoto Pharmaceutical University, Faculty of Pharmaceutical Science, 2002.03, Graduated

Graduate School 【 display / non-display

  • Osaka University, Graduate School, Division of Pharmaceutical Sciences, Master's Course, 2004.03, Completed

  • Kyoto University, Graduate School, Division of Medicine, Doctor's Course, 2007.03, Completed

Campus Career 【 display / non-display

  • 1900.01
    -
    2016.02
    Tokyo Medical and Dental University, Medical Research Institute, Pathophysiology, Stem Cell Biology, Assistant Professor
  • 2010.07
    -
    Now
    Tokyo Medical and Dental University, Medical Research Institute, Pathophysiology, Stem Cell Biology, Assistant Professor

Qualification Acquired 【 display / non-display

  • Pharmacist

 

Published Papers & Misc 【 display / non-display

  1. Morinaga Hironobu, Mohri Yasuaki, Grachtchouk Marina, Asakawa Kyosuke, Matsumura Hiroyuki, Oshima Motohiko, Takayama Naoya, Kato Tomoki, Nishimori Yuriko, Sorimachi Yuriko, Takubo Keiyo, Suganami Takayoshi, Iwama Atsushi, Iwakura Yoichiro, Dlugosz Andrzej A., Nishimura Emi K.. Obesity accelerates hair thinning by stem cell-centric converging mechanisms NATURE. 2021.07; 595 (7866): 266-+. ( DOI )

  2. Al-Busani Hind, Al-Sobaihi Saber, Nojima Kohei, Tanemura Atsushi, Yaguchi Tomonori, Kawakami Yutaka, Matsumura Hiroyuki, Nishimura Emi K., Yokozeki Hiroo, Namiki Takeshi. NUAK2 localization in normal skin and its expression in a variety of skin tumors with YAP JOURNAL OF DERMATOLOGICAL SCIENCE. 2020.02; 97 (2): 143-151. ( DOI )

  3. Al-Busani Hind, Al-Sobaihi Saber, Nojima Kohei, Tanemura Atsushi, Yaguchi Tomonori, Kawakami Yutaka, Matsumura Hiroyuki, Nishimura Emi K., Yokozeki Hiroo, Namiki Takeshi. 正常皮膚におけるNUAK2の局在と種々のYAPを有する皮膚腫瘍での発現(NUAK2 localization in normal skin and its expression in a variety of skin tumors with YAP) Journal of Dermatological Science. 2020.02; 97 (2): 143-151. ( ichushi )

  4. Liu Nan, Matsumura Hiroyuki, Kato Tomoki, Ichinose Shizuko, Takada Aki, Namiki Takeshi, Asakawa Kyosuke, Morinaga Hironobu, Mohri Yasuaki, Nanba Daisuke, Nishimura Emi K.. 皮膚の恒常性と加齢をコントロールする幹細胞競合(Stem cell competition underlies skin homeostasis and aging) 日本研究皮膚科学会年次学術大会・総会プログラム. 2019.10; 44回 131. ( ichushi )

  5. Liu N., Matsumura H., Kato T., Ichinose S., Takada A., Namiki T., Asakawa K., Morinaga H., Mohri Y., Arcangelis A., Georges-Labouesse E., Nanba D., Nishimura E. K.. Epidermal stem cell competition orchestrates skin organ homeostasis and aging JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019.09; 139 (9): S313.

  6. Liu Nan, Matsumura Hiroyuki, Kato Tomoki, Ichinose Shizuko, Takada Aki, Namiki Takeshi, Asakawa Kyosuke, Morinaga Hironobu, Mohri Yasuaki, De Arcangelis Adele, Geroges-Labouesse Elisabeth, Nanba Daisuke, Nishimura Emi K.. Stem cell competition orchestrates skin homeostasis and ageing NATURE. 2019.04; 568 (7752): 344-+. ( DOI )

  7. Noguchi S, Honda S, Saitoh T, Matsumura H, Nishimura E, Akira S, Shimizu S. Beclin 1 regulates recycling endosome and is required for skin development in mice. Communications biology. 2019; 2 37. ( PubMed, DOI )

  8. Nishimura Emi, Kato Tomoki, Matsumura Hiroyuki, Liu Nan. 幹細胞は毛包老化プログラムを制御する(Stem cells orchestrate hair follicle aging program) Experimental Animals. 2018.07; 67 (Suppl.): S20. ( ichushi )

  9. Namiki T., Matsumura H., Yaguchi T., Kawakami Y., Nishimura E., Yokozeki H.. NUAK2 promote melanoma development by regulating mTOR pathway JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018.05; 138 (5): S201.

  10. Nanba Daisuke, Mohri Yasuaki, Okamoto Sakura, Matsumura Hiroyuki, Usami Takako, Aida Tomomi, Tanaka Koichi, Nishimura Emi K.. クローニングフリーCRISPR/Cas9技術によるDct遺伝子座を有するメラノサイト幹細胞の標的化(Targeting melanocyte stem cells with Dct locus by cloning-free CRISPR/Cas9 technology) 日本研究皮膚科学会年次学術大会・総会プログラム. 2017.11; 42回 253. ( ichushi )

  11. Matsumura H., Mohri Y., Nguyen T., Morinaga H., Fukuda M., Ito M., Kurata S., Hoeijmakers J., Nishimura E. K.. Defective maintenance of hair follicle stem cells through COL17A1 loss orchestrates the hair follicle aging program JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017.10; 137 (10): S235.

  12. Nanba D., Toki F., Matsumura H., Toki H., Nishimura E. K.. Locomotive ability of human keratinocyte stem cells is an intrinsic property for stem cell expansion and epidermal reconstruction JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017.10; 137 (10): S310.

  13. Matsumura H, Mohri Y, Binh NT, Morinaga H, Fukuda M, Ito M, Kurata S, Hoeijmakers J, Nishimura EK. Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis. Science (New York, N.Y.). 2016.02; 351 (6273): aad4395. ( PubMed, DOI )

  14. Tokuhiro K, Satouh Y, Nozawa K, Isotani A, Fujihara Y, Hirashima Y, Matsumura H, Takumi K, Miyano T, Okabe M, Benham AM, Ikawa M. Calreticulin is required for development of the cumulus oocyte complex and female fertility. Scientific reports. 2015.09; 5 14254. ( PubMed, DOI )

  15. Shehata M, Matsumura H, Okubo-Suzuki R, Ohkawa N, Inokuchi K. Neuronal stimulation induces autophagy in hippocampal neurons that is involved in AMPA receptor degradation after chemical long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012.07; 32 (30): 10413-22. ( PubMed, DOI )

  16. Tada M, Matsumura H, Kurose Y, Nakatsuji N, Tada T. Target chromosomes of inducible deletion by a Cre/inverted loxP system in mouse embryonic stem cells. Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology. 2009; 17 (4): 443-50. ( PubMed, DOI )

  17. Otsuji T, Matsumura H, Suzuki T, Nakatsuji N, Tada T, Tada M. Rapid induction of large chromosomal deletions by a Cre/inverted loxP system in mouse ES Cell hybrids. Journal of molecular biology. 2008.04; 378 (2): 328-36. ( PubMed, DOI )

  18. Matsumura H, Tada T. Cell fusion-mediated nuclear reprogramming of somatic cells. Reproductive biomedicine online. 2008.01; 16 (1): 51-6. ( PubMed )

  19. Matsumura H, Tada M, Otsuji T, Yasuchika K, Nakatsuji N, Surani A, Tada T. Targeted chromosome elimination from ES-somatic hybrid cells. Nature methods. 2007.01; 4 (1): 23-5. ( PubMed, DOI )

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Patents 【 display / non-display

  • COMPOSITION FOR PREVENTING OR AMELIORATING LOSS OF HAIR AND GRAYING OF HAIR, AND USE THEREOF

    Patent Number: 10702544