論文・総説 - 長谷　武志

21. Kawakami E, Singh VK, Matsubara K, Ishii T, Matsuoka Y, Hase T, Kulkarni P, Siddiqui K, Kodilkar J, Danve N, Subramanian I, Katoh M, Shimizu-Yoshida Y, Ghosh S, Jere A, Kitano H. Network analyses based on comprehensive molecular interaction maps reveal robust control structures in yeast stress response pathways. NPJ systems biology and applications. 2016; 2 15018. ( PubMed, DOI )

22. Hase T, Kikuchi K, Ghosh S, Kitano H, Tanaka H. Controllability of protein-protein interaction networks and their relationships with drug-targets, essential genes, and degree connectivities. The proceedings of The 20th International Symposium on Artificial Life and Robotics 2015 (AROB 20th 2015). 2015.01; 813-818.

23. Takeshi Hase, Kaito Kikuchi, Samik Ghosh, Hiroaki Kitano, Hiroshi Tanaka. (Research article) Identification of drug-target modules in the human protein–protein interaction network Artificial Life and Robotics. 2014.12; 19 (4): 406-413. ( DOI )

24. Matsuoka Y, Matsumae H, Katoh M, Eisfeld AJ, Neumann G, Hase T, Ghosh S, Shoemaker JE, Lopes TJ, Watanabe T, Watanabe S, Fukuyama S, Kitano H, Kawaoka Y. A comprehensive map of the influenza A virus replication cycle. BMC systems biology. 2013.10; 7 (97): 97. ( PubMed, DOI )

25. Hase T, Ghosh S, Yamanaka R, Kitano H. Harnessing diversity towards the reconstructing of large scale gene regulatory networks. PLoS computational biology. 2013; 9 (11): e1003361. ( PubMed, DOI )

26. (Book Chapter) "Chapter 20. Protein-Protein Interaction Networks: Structures, Evolution, and Application to Drug Design" - Protein-Protein Interactions - Computational and Experimental Tools (W. Cai, H. Hong (eds.)) 2012.03; 405-426. ( DOI )

27. Hanada K, Hase T, Toyoda T, Shinozaki K, Okamoto M. Origin and evolution of genes related to ABA metabolism and its signaling pathways. Journal of plant research. 2011.07; 124 (4): 455-65. ( PubMed, DOI )

28. Hase T, Niimura Y, Tanaka H. Difference in gene duplicability may explain the difference in overall structure of protein-protein interaction networks among eukaryotes. BMC evolutionary biology. 2010.11; 10 358. ( PubMed, DOI )

29. Hase T, Tanaka H, Suzuki Y, Nakagawa S, Kitano H. Structure of protein interaction networks and their implications on drug design. PLoS computational biology. 2009.10; 5 (10): e1000550. ( PubMed, DOI )

30. Hase T, Niimura Y, Kaminuma T, Tanaka H. Non-uniform survival rate of heterodimerization links in the evolution of the yeast protein-protein interaction network. PloS one. 2008.02; 3 (2): e1667. ( PubMed, DOI )

31. 長谷 武志, 荻島 創一, 中川 草, 田中 博. 1P301 タンパク質間相互作用ネットワークのトポロジー構造における構造決定因子について(数理生物学)) 生物物理. 2005; 45 S107. ( DOI )

32. Tsuji Shingo, Aburatani Hiroyuki, Hase Takeshi, Tanaka Hiroshi. Applications of graph neural networks for drug-repositioning and cancer research CANCER SCIENCE. 2022.02; 113 1790.

33. Shirakami Arata, Toba Takuma, Nakamoto Isao, Hase Takeshi, Shimono Masanori. Deep neural embedding of neuronal connectivity JOURNAL OF COMPUTATIONAL NEUROSCIENCE. 2021.12; 49 (SUPPL 1): S172-S173.

34. Tsuji Shingo, Hase Takeshi, Yachie-Kinoshita Ayako, Nishino Taiko, Ghosh Samik, Kikuchi Masataka, Shimokawa Kazuro, Aburatani Hiroyuki, Kitano Hiroaki, Tanaka Hiroshi. Artificial intelligence-based computational framework for drug-target prioritization and inference of novel repositionable drugs for Alzheimer's disease ALZHEIMERS RESEARCH & THERAPY. 2021.05; 13 (1): 92. ( PubMed, DOI )

35. 長谷 武志, 谷内江 綾子, 辻 真吾. AI とBig Data におけるDrug Discovery（創薬）への可能性 ICUとCCU. 2019.06; 43 (4): 191-198.

36. Ackerman Emily E., Alcorn John F., Hase Takeshi, Shoemaker Jason E.. A dual controllability analysis of influenza virus-host protein-protein interaction networks for antiviral drug target discovery BMC BIOINFORMATICS. 2019.06; 20 (1): 297. ( PubMed, DOI )

37. Tsuji Shingo, Hase Takeshi, Tanaka Hiroshi, Aburatani Hiroyuki. Al technology based drug discovery method with protein interaction network for cancer drug repositioning CANCER SCIENCE. 2018.01; 109 786.

38. 肥田 道彦, 長谷 武志, 濱 智子, 池田 裕美子, 八幡 憲明, 舘野 周, 高橋 英彦, 松浦 雅人, 鈴木 秀典, 大久保 善朗. 恐怖音声認知・脳処理時の機能的結合に対するプラセボ・ロラゼパムの効果 機能的MRI研究 日本神経精神薬理学会年会プログラム・抄録集. 2016.07; 46回 215. ( 医中誌 )

39. 長谷 武志, 荻島 創一, 鈴木 泰博, 中川 草, 田中 博. 1P297 タンパク質間相互作用ネットワークの進化における疎密構造と自己結合するタンパク質の持つ相互作用数の頻度分布との関係(数理生物学) 生物物理. 2004; 44 S104. ( DOI )

40. 長谷 武志, 鈴木 泰博, 荻島 創一, 田中 博. タンパク質間相互作用ネットワークの枝数による階層構造 生物物理. 2003; 43 S244. ( DOI )