Graduating School 【 display / non-display 】
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Tokyo Medical and Dental University, Faculty of Dentistry, 1997, Graduated
Graduate School 【 display / non-display 】
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Tokyo Medical and Dental University, Graduate School, Division of Dental Research, Doctor's Course, 2001, Completed
Degree 【 display / non-display 】
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Doctor of Dental Science, Tokyo Medical and Dental University
Campus Career 【 display / non-display 】
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2001.04-2002.03Tokyo Medical and Dental University, (Old Organization)Dental Hospital, Hospital Departments, Clinics for Conservation of Oral and Maxillofacial Function, Periodontics, Dental Resident
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2004.04-2009.03Tokyo Medical and Dental University, (Old Organization)Dental Hospital, Hospital Departments, Clinics for Conservation of Oral and Maxillofacial Function, Periodontics, Dental Resident
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2009.04-2017.03Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Periodontology, Assistant Professor
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2017.04-2023.03Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Periodontology, Junior Associate Professor
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2023.04-2023.08Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Health Sciences and Biomedical Engineering, Department of Lifetime Oral Health Care Sciences, Junior Associate Professor
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2023.09-2024.05Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Biomedical Sciences and Engineering, Division of Oral Health Sciences, Department of Lifetime Oral Health Care Sciences, Junior Associate Professor
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2024.06-NowTokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Biomedical Sciences and Engineering, Division of Oral Health Sciences, Department of Lifetime Oral Health Care Sciences, Professor
External Career 【 display / non-display 】
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2002.03-2004.03University of Geneva, Department of Preventive and oral pathology, School of Dental Medicine, Assistant Professor
Academic Society Affiliations 【 display / non-display 】
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Japanese Society of Periodontology
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Japanese Society of Conservative Dentistry
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Stomatological Society
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Japanese Society of Oral Implantology
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Japanese Society for Laser Dentistry
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Japanese Dental Education Association
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Japanese Society for Bacteriology
Published Papers & Misc 【 display / non-display 】
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G Tanabe, T Hasunuma, Y Takeuchi, H Churei, K Hayashi, K Togawa, N Moriya, T Ueno. Assessment of Exercise-Induced Dehydration Status Based on Oral Mucosal Moisture in a Field Survey Dentistry Journal. 2024.12; 13 (1): 5. ( DOI )
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Shimizu S, Hayashi K, Takeuchi Y, Tanabe G, Churei H, Kobayashi H, Ueno T, Fueki T. Effect of Porphyromonas gingivalis infection on healing of skeletal muscle injury: An in vivo study Dentistry Journal. 2024.10; 12 (11): 346. ( DOI )
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Okano T, Ashida H, Komatsu N, Tsukasaki M, Iida T, Iwasawa M, Takahashi Y, Takeuchi Y, Iwata T, Sasai M, Yamamoto M, Takayanagi H, Suzuki T. Caspase-11 mediated inflammasome activation in macrophages by systemic infection of A. actinomycetemcomitans exacerbates arthritis. International journal of oral science. 2024.08; 16 (1): 54. ( PubMed, DOI )
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Yokose M, Komatsu K, Shiba T, Tanaka D, Takeuchi Y, Ikeda Y. Gnetin-C, a resveratrol dimer, inhibits the growth and virulence of Porphyromonas gingivalis 口腔病学会雑誌. 2024.03; 91 (1): 47-65. ( ichushi )
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Nagai T, Shiba T, Komatsu K, Matsumura S, Koyanagi T, Nemoto T, Kobayashi R, Takeuchi Y, Iwata T.. Characterizing bacterial communities among healthy, peri-implant mucositis, and peri-implantitis statuses by 16S rRNA gene amplicon sequencing 口腔病学会雑誌. 2024.03; 91 (1): 8-18. ( ichushi )
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Shiba T, Komatsu K, Takeuchi Y, Koyanagi T, Taniguchi Y, Takagi T, Maekawa S, Nagai T, Kobayashi R, Matsumura S, Katagiri S, Izumi Y, Aoki A, Iwata T. Novel flowchart guiding the non-surgical and surgical management of peri-implant complications: a narrative review Bioenginnering. 2024.01; 11 (2): 118.
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Takeuchi Y, Aoki A, Hiratsuka K, Chui C, Ichinose A, Aung N, Kitanaka Y, Hayashi S, Toyoshima K, Iwata T, Arakawa S. Application of different wavelengths of LED lights in antimicrobial photodynamic therapy for the treatment of periodontal disease. Antibiotics (Basel). 2023.11; 12 (12): ( PubMed, DOI )
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Hayashi S, Takeuchi Y, Hiratsuka K, Kitanaka Y, Toyoshima K, Nemoto T, Aung N, Hakariya M, Ikeda Y, Iwata T, Aoki A. Effects of various light-emitting diode wavelengths on periodontopathic bacteria and gingival fibroblasts: An in vitro study. Photodiagnosis and Photodynamic Therapy. 2023.10; 44 103860. ( PubMed, DOI )
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Hirasawa I, Odagiri H, Park G, Sanghavi R, Oshita T, Togi A, Yoshikawa K, Mizutani K, Takeuchi Y, Kobayashi H, Katagiri S, Iwata T, Aoki A. Anti-inflammatory effects of cold atmospheric plasma irradiation on the THP-1 human acute monocytic leukemia cell line. PloS one. 2023.10; 18 (10): e0292267. ( PubMed, DOI )
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Takeuchi Y, Nemoto T, Kitanaka Y, Aoki A, Izumi Y, Iwata T, Arakawa S. Antibacterial activity of lysozyme-chitosan oligosaccharide conjugates on two periodontal bacteria Oral diseases. 2023.08; 30 (4): 2728-2735. ( PubMed, DOI )
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Ikeda Y, Chigasaki O, Mizutani K, Sasaki Y, Aoyama N, Mikami R, Gokyu M, Umeda M, Izumi Y, Aoki A, Takeuchi Y. The potential of a saliva test for screening of alveolar bone resorption Healthcare. 2023.07; 11 (13): 1822. ( PubMed, DOI )
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Shiba T, Komatsu K, Watanabe T, Takeuchi Y, Nemoto T, Ohsugi Y, Katagiri S, Shimogishi M, Marukawa E, Iwata T. Peri-implantitis management by resective surgery combined with implantoplasty and Er:YAG laser irradiation, accompanied by free gingival graft: a case report. Therapeutic advances in chronic disease. 2023.06; 14 20406223231174816. ( PubMed, DOI )
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Hayashi K, Takeuchi Y, Shimizu S, Tanabe G, Churei H, Kobayashi H, Ueno T. Continuous oral administration of sonicated P. gingivalis delays rat skeletal muscle healing post-treadmill training International Journal of Environmental Research and Public Health. 2022.10; 19 (20): ( PubMed, DOI )
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Shiba T, Katagiri S, Komatsu K, Nemoto T, Takeuchi Y, Chen B, Zhou YS, Iwata T. Treatment of peri-implantitis caused by malpositioning and an extra implant: a case report International Journal of Periodontics & Restorative Dentistry. 2022.01; 42 (1): e15-e20. ( PubMed, DOI )
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Nemoto T, Shiba T, Komatsu K, Watanabe T, Shimogishi M, Shibasaki M, Koyanagi T, Nagai T, Katagiri S, Takeuchi Y, Iwata T. Discrimination of bacterial community structures among healthy, gingivitis, and periodontitis statuses through integrated metatranscriptomic and network analyses. mSystems. 2021.10; 6 (6): e0088621. ( PubMed, DOI )
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Shiba T, Komatsu K, Sudo T, Sawafuji R, Saso A, Ueda S, Watanabe T, Nemoto T, Kano C, Nagai T, Ohsugi Y, Katagiri S, Takeuchi Y, Kobayashi H, Iwata T. Comparison of periodontal bacteria of Edo and modern periods using novel diagnostic approach for periodontitis with micro-CT. Frontiers in cellular and infection microbiology. 2021.09; 11 723821. ( PubMed, DOI )
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Tanabe G, Hasunuma T, Inai Y, Takeuchi Y, Kobayashi H, Hayashi K, Shimizu S, Kamiya N, Churei H, Sumita Y, Suzuki K, Moriya N, Ueno T. Potential assessment of dehydration during high-intensity training using a capacitance sensor for oral mucosal moisture: evaluation of elite athletes in a field-based survey. Chemosensors. 2021.07; 9 (8): 196. ( DOI )
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Shiba T, Watanabe T, Komatsu K, Koyanagi T, Nemoto T, Ohsugi Y, Michi Y, Katagiri S, Takeuchi Y, Ishihara K, Iwata T. Non-surgical treatment for periodontitis and peri-implantitis: longitudinal clinical and bacteriological findings-A case report with a 7-year follow-up evaluation. SAGE open medical case reports. 2021.07; 9 2050313X211029154. ( PubMed, DOI )
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Tanabe G, Churei H, Takeuchi Y, Hayashi K, Kanasaki A, Yoshida Y, Toma J, Araie Y, Ueno T. Antibacterial effect of a disinfectant spray for sports mouthguards on Streptococcus sobrinus Dental research journal. 2021.07; 18 59. ( PubMed )
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Rophukdeekul S, Tabata M, Ratanaporncharoen C, Takeuchi Y, Somboon P, Boonlue W, Miyahara Y, Sriyudthsak M. Quantitative assessment of periodontal bacteria using a cell-based immunoassay with functionalized QCM Chemosensors. 2021.06; 9 (7): 159. ( DOI )
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Chigasaki O, Aoyama N, Sasaki Y, Takeuchi Y, Mizutani K, Ikeda Y, Gokyu M, Umeda M, Izumi Y, Iwata T, Aoki A. Porphyromonas gingivalis, the most influential pathogen in red-complex bacteria: A cross-sectional study on the relationship between bacterial count and clinical periodontal status in Japan J Periodontol. 2021.04; 92 (12): 1719-1729. ( PubMed, DOI )
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Harada Y, Sunaga M, Takeuchi Y, Mizutani K, Katagiri S, Ikeda Y, Aoki A, Iwata T, Kinoshita A. Standardization of examiners using a dental model for pocket probe training: Adequacy of evaluation with model and standard accuracy rate of skilled examiners Journal of Medical and Dental Sciences. 2021.02; 68 49-54.
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Komatsu K, Shiba T, Takeuchi Y, Watanabe T, Koyanagi T, Nemoto T, Shimogishi M, Shibasaki M, Katagiri S, Kasugai S, Iwata T. Discriminating microbial community structure between peri-Implantitis and periodontitis with integrated metagenomic, metatranscriptomic, and network analysis Frontiers in Cellular and Infection Microbiology. 2020.12; 10 596490. ( PubMed, DOI )
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Kitanaka Y, Takeuchi Y, Hiratsuka K, Aung N, Sakamaki Y, Nemoto T, Meinzer W, Izumi Y, Iwata T, Aoki A. The effect of antimicrobial photodynamic therapy using yellow-green LED and rose bengal on Porphyromonas gingivalis. Photodiagnosis and photodynamic therapy, Tokyo Medical and Dental University. 2020.12; 32 102033. ( PubMed, DOI )
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Ogawa M, Katagiri S, Koyanagi T, Maekawa S, Shiba T, Ohsugi Y, Takeuchi Y, Ikawa T, Takeuchi S, Sekiuchi T, Arai Y, Kazama R, Wakabayashi N, Izumi Y, Iwata T. Accuracy of cone beam computed tomography in evaluation of palatal mucosa thickness. Journal of Clinical Periodontology. 2020.04; 47 (4): 479-488. ( PubMed, DOI )
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Ye C, Kobayashi H, Katagiri S, Miyasaka N, Takeuchi Y, Kuraji R, Izumi Y. The relationship between the anti-Porphyromonas gingivalis immunoglobulin G subclass antibody and small for gestational age delivery: a longitudinal study in pregnant Japanese women. International dental journal. 2020.03; 70 (4): 296-302. ( PubMed, DOI )
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Ikeda E, Shiba T, Ikeda Y, Suda W, Nakasato A, Takeuchi Y, Azuma M, Hattori M, Izumi Y. Japanese subgingival microbiota in health vs disease and their roles in predicted functions associated with periodontitis. Odontology. 2019.09; 108 (2): 280-291. ( PubMed, DOI )
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Aung N, Aoki A, Takeuchi Y, Hiratsuka K, Katagiri S, Kong S, Shujaa Addin A, Meinzer W, Sumi Y, Izumi Y. The effects of ultraviolet light-emitting diodes with different wavelengths on periodontopathic acteria In Vitro. Photobiomodulation, photomedicine, and laser surgery. 2019.05; 37 (5): 288-297. ( PubMed, DOI )
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Funahashi K, Shiba T, Watanabe T, Muramoto K, Takeuchi Y, Ogawa T, Izumi Y, Sekizaki T, Nakagawa I, Moriyama K. Functional dysbiosis within dental plaque microbiota in cleft lip and palate patients. Progress in orthodontics. 2019.03; 20 (1): 11. ( PubMed, DOI )
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Ikeda E, Shiba T, Ikeda Y, Suda W, Nakasato A, Takeuchi Y, Azuma M, Hattori M, Izumi Y. Deep sequencing reveals specific bacterial signatures in the subgingival microbiota of healthy subjects. Clinical oral investigations. 2019.03; 23 (3): 1489-1493. ( PubMed, DOI )
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Ohtsu A, Takeuchi Y, Katagiri S, Suda W, Maekawa S, Shiba T, Komazaki R, Udagawa S, Sasaki N, Hattori M, Izumi Y. Influence of Porphyromonas gingivalis in gut microbiota of streptozotocin-induced diabetic mice. Oral diseases. 2019.01; 25 (3): 868-880. ( PubMed, DOI )
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Sasaki N, Katagiri S, Komazaki R, Watanabe K, Maekawa S, Shiba T, Udagawa S, Takeuchi Y, Ohtsu A, Kohda T, Tohara H, Miyasaka N, Hirota T, Tamari M, Izumi Y. Endotoxemia by Porphyromonas gingivalis injection aggravates non-alcoholic fatty liver disease, disrupts glucose/lipid metabolism, and alters gut microbiota in mice. Frontiers in Microbiology. 2018.10; 9 2470. ( PubMed, DOI )
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Lee BS, Shih KS, Lai CH, Takeuchi Y, Chen YW. Surface property alterations and osteoblast attachment to contaminated titanium surfaces after different surface treatments: An in vitro study. Clinical implant dentistry and related research. 2018.08; 20 (4): 583-591. ( PubMed, DOI )
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Chigasaki O, Takeuchi Y, Aoki A, Sasaki Y, Mizutani K, Aoyama N, Ikeda Y, Gokyu M, Umeda M, Ishikawa I, Izumi Y. A cross-sectional study on the periodontal status and prevalence of red complex periodontal pathogens in a Japanese population. J Oral Sci. 2018.06; 60 (2): 293-303. ( PubMed, DOI )
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Yoshida Y, Churei H, Takeuchi Y, Wada T, Uo M, Izumi Y, Ueno T. Novel antibacterial mouthguard material manufactured using silver-nanoparticle-embedded ethylene-vinyl acetate copolymer masterbatch. Dental Materials Journal. 2018.06; 37 (3): 437-444. ( PubMed, DOI )
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Sugawara Y, Imai K, Kashimada A, Moriyama K, Baba S, Nishikomori R, Motegi M, Takeuchi Y, Morio T. Autoinflammatory phenotypes in Aicardi-Goutières syndrome with interferon upregulation and serological autoimmune features. J Allergy Clin Immunol. 2018.03; 141 (3): 1135-1138. ( PubMed, DOI )
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Udagawa S, Katagiri S, Maekawa S, Takeuchi Y, Komazaki R, Ohtsu A, Sasaki N, Shiba T, Watanabe K, Ishihara K, Sato N, Miyasaka N, Izumi Y. Effect of Porphyromonas gingivalis infection in the placenta and umbilical cord in pregnant mice with low birth weight. Acta Odontologica Scandinavica. 2018.01; 1-9. ( PubMed, DOI )
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Rina Komazaki, Sayaka Katagiri, Hirokazu Takahashi, Shogo Maekawa, Takahiko Shiba, Yasuo Takeuchi, Yoichiro Kitajima, Anri Ohtsu, Sayuri Udagawa, Naoki Sasaki, Kazuki Watanabe, Noriko Sato, Naoyuki Miyasaka, Yuichiro Eguchi, Keizo Anzai, Yuichi Izumi. Periodontal pathogenic bacteria, Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolism. Sci Rep. 2017.10; 7 (1): 13950. ( PubMed, DOI )
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S Maekawa, S Katagiri, Y Takeuchi, R Komazaki, A Ohtsu, S Udagawa, Y Izumi. Bone metabolic microarray analysis of ligature-induced periodontitis in streptozotocin-induced diabetic mice. J Periodont Res. 2017.04; 52 (2): 233-245. ( PubMed, DOI )
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Kachi H, Maruyama N, Maruyama F, Shiba T, Watanabe T, Goda A, Murase K, Michi Y, Takeuchi Y, Izumi Y, Harada K, Nakagawa I. Active microbiota show specific correlationships in peri-implantitis and periodontitis. 口腔病学会雑誌. 2017.03; 84 (1): 25-36.
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Ogata Y, Nakayama Y, Tatsumi J, Kubota T, Sato S, Nishida T, Takeuchi Y, Onitsuka T, Sakagami R, Nozaki T, Murakami S, Matsubara N, Tanaka M, Yoshino T, Ota J, Nakagawa T, Ishihara Y, Ito T, Saito A, Yamaki K, Matsuzaki E, Hidaka T, Sasaki D, Yaegashi T, Yasuda T, Shibutani T, Noguchi K, Araki H, Ikumi N, Aoyama Y, Kogai H, Nemoto K, Deguchi S, Takiguchi T, Yamamoto M, Inokuchi K, Ito T, Kado T, Furuichi Y, Kanazashi M, Gomi K, Takagi Y, Kubokawa K, Yoshinari N, Hasegawa Y, Hirose T, Sase T, Arita H, Kodama T, Shin K, Izumi Y, Yoshie H. Prevalence and risk factors for peri-implant diseases in Japanese adult patients. A cross-sectional multi-center study by periodontal specialist. J Oral Sci. 2017.03; 59 (1): 1-11. ( PubMed, DOI )
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Uekubo A, Hiratsuka K, Aoki A, Takeuchi Y, Abiko Y, Izumi Y. Effect of antimicrobial photodynamic therapy using rose bengal and blue light-emitting diode on Porphyromonas gingivalis in vitro: Influence of oxygen during treatment Laser Therapy. 2016.12; 25 (4): 299-308. ( PubMed )
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Lee BS, Lee CC, Lin HP, Shih WA, Hsieh WL, Lai CH, Takeuchi Y, Chen YW. A functional chitosan membrane with grafted epigallocatechin-3-gallate and lovastatin enhances periodontal tissue regeneration in dogs. Carbohydr Polym. 2016.10; 151 790-802. ( PubMed, DOI )
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Shiba T, Watanabe T, Kachi H, Koyanagi T, Maruyama N, Murase K, Takeuchi Y, Maruyama F, Izumi Y, Nakagawa I. Distinct interacting core taxa in co-occurrence networks enable discrimination of polymicrobial oral diseases with similar symptoms. Sci Rep. 2016.08; 6 30997. ( PubMed, DOI )
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Mayumi Ogita, Sachio Tsuchida, Akira Aoki, Mamoru Satoh, Sayaka Kado, Masanori Sawabe, Hiromi Nanbara, Hiroaki Kobayashi, Yasuo Takeuchi, Koji Mizutani, Yoshiyuki Sasaki, Fumio Nomura, Yuichi Izumi. Increased cell proliferation and differential protein expression induced by low-level Er:YAG laser irradiation in human gingival fibroblasts: proteomic analysis. Lasers Med Sci. 2015.09; 30 (7): 1855-1866. ( PubMed, DOI )
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Ichinose-Tsuno A, Aoki A, Takeuchi Y, Kirikae T, Shimbo T, Lee MC, Yoshino F, Maruoka Y, Itoh T, Ishikawa I, Izumi Y. Antimicrobial photodynamic therapy suppresses dental plaque formation in healthy adults: a randomized controlled clinical trial. BMC Oral Health. 2014.12; 14 152. ( PubMed, DOI )
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Maruyama N, Maruyama F, Takeuchi Y, Aikawa C, Izumi Y, Nakagawa I. Intraindividual variation in core microbiota in peri-implantitis and periodontitis. Scientific reports. 2014.10; 4 6602. ( PubMed, DOI )
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Chui C, Aoki A, Takeuchi Y, Sasaki Y, Hiratsuka K, Abiko Y, Izumi Y. Antimicrobial effect of photodynamic therapy using high-power blue light-emitting diode and red-dye agent on Porphyromonas gingivalis. J Periodont Res. 2013.12; 48 (6): 696-705. ( PubMed, DOI )
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Tsuchida S, Satoh M, Kawashima Y, Sogawa K, Kado S, Sawai S, Nishimura M, Ogita M, Takeuchi Y, Kobyashi H, Aoki A, Kodera Y, Matsushita K, Izumi Y, Nomura F. Application of quantitative proteomic analysis using tandem mass tags for discovery and identification of novel biomarkers in periodontal disease. Proteomics. 2013.08; 13 (15): 2339-2350. ( PubMed, DOI )
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Taniguchi Y, Aoki A, Mizutani K, Takeuchi Y, Ichinose S, Takasaki AA, Schwarz F, Izumi Y. Optimal Er:YAG laser irradiation parameters for debridement of microstructured fixture surfaces of titanium dental implants. Lasers Med Sci. 2013.07; 28 (4): 1057-1068. ( PubMed, DOI )
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Ye C, Katagiri S, Miyasaka N, Bharti P, Kobayashi H, Takeuchi Y, Momohara Y, Sekiguchi M, Takamine S, Nagasawa T, Izumi Y. The anti-phospholipid antibody-dependent and independent effects of periodontopathic bacteria on threatened preterm labor and preterm birth. Arch Gynecol Obstet. 2013.07; 288 (1): 65-72. ( PubMed, DOI )
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Bharti P, Katagiri S, Nitta H, Nagasawa T, Kobayashi H, Takeuchi Y, Izumiyama H, Uchimura I, Inoue S, Izumi Y. Periodontal treatment with topical antibiotics improves glycemic control in association with elevated serum adiponectin in patients with type 2 diabetes mellitus. Obes Res Clin Pract. 2013.03; 7 (2): e129-e138. ( PubMed, DOI )
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Koyanagi T, Sakamoto M, Takeuchi Y, Maruyama N, Ohkuma M, Izumi Y. Comprehensive microbiological findings in peri-implantitis and periodontitis. J Clin Periodontol. 2013.03; 40 (3): 218-226. ( PubMed, DOI )
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Chui C, Hiratsuka K, Aoki A, Takeuchi Y, Abiko Y, Izumi Y. Blue LED inhibits the growth of Porphyromonas gingivalis by suppressing the expression of genes associated with DNA replication and cell division. Lasers Surg Med. 2012.12; 44 (10): 856-864. ( PubMed, DOI )
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Takeuchi Y, Nagasawa T, Katagiri S, Kitagawara S, Kobayashi H, Koyanagi T, Izumi Y. Salivary levels of antibacterial peptide (LL-37/hCAP-18) and cotinine in patients with chronic periodontitis. J Periodontol. 2012.06; 83 (6): 766-772. ( PubMed, DOI )
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Aoyama N, Suzuki J, Wang D, Ogawa M, Kobayashi N, Hanatani T, Takeuchi Y, Izumi Y, Isobe M. Porphyromonas gingivalis promotes murine abdominal aortic aneurysms via matrix metalloproteinase-2 induction. J Periodont Res. 2011.04; 46 (2): 176-183. ( PubMed, DOI )
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Koyanagi T, Sakamoto M, Takeuchi Y, Ohkuma M, Izumi Y. Analysis of microbiota associated with peri-implantitis using 16S rRNA gene clone library. J Oral Microbiol. 2010; 2 1-7.
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Chen YW, Nagasawa T, Wara-Aswapati N, Ushida Y, Wang D, Takeuchi Y, Kobayashi H, Umeda M, Inoue Y, Iwai T, Ishikawa I, Izumi Y. Association between periodontitis and anti-cardiolipin antibodies in Buerger disease. J Clin Periodontol. 2009.10; 36 (10): 830-835. ( PubMed, DOI )
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Izumi Y, Nagasawa T, Umeda M, Kobayashi H, Takeuchi Y, Yashiro R, Hormdee D, Suda T, Ushida Y, and Nawarat WA. Periodontitis and cardiovascular diseases: The link and relevant mechanisms. The Japanese Dental Science Review. 2009.02; 45 98-108.
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Wang D, Nagasawa T, Chen Y, Ushida Y, Kobayashi H, Takeuchi Y, Umeda M, Izumi Y. Molecular mimicry of Aggregatibacter actinomycetemcomitans with b2 glycoprotein I. Oral Microbiol Immunol. 2008.10; 23 (5): 401-405. ( PubMed, DOI )
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Chen YW, Umeda M, Nagasawa T, Takeuchi Y, Huang Y, Inoue Y, Iwai T, Izumi Y, Ishikawa I. Periodontitis may increase the risk of peripheral arterial disease. Eur J Vasc Endovasc Surg. 2008.02; 35 (2): 153-158. ( PubMed, DOI )
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Takeuchi Y, Guggenheim B, Filieri A, Baehni P. Effect of chlorhexidine/thymol and fluoride varnishes on dental biofilm formation in vitro. Eur J Oral Sci. 2007.12; 115 (6): 468-472. ( PubMed, DOI )
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Chen YW, Iwai T, Umeda M, Nagasawa T, Huang Y, Takeuchi Y, Ishikawa I. Elevated IgG titers to periodontal pathogens related to Buerger disease. Int J Cardiol. 2007.10; 122 (1): 79-81. ( PubMed, DOI )
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Thiha K, Takeuchi Y, Umeda M, Huang Y, Ohnishi M, Ishikawa I. Identification of periodontopathic bacteria in gingival tissue of Japanese periodontitis patients. Oral Microbiol Immunol. 2007.06; 22 (3): 201-207. ( PubMed, DOI )
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Takeuchi Y, Aramaki M, Nagasawa T, Umeda M, Oda S, Ishikawa I. Immunoglobulin G subclass antibody profiles in Porphyromonas gingivalis-associated aggressive and chronic periodontitis patients. Oral Microbiol Immunol. 2006.10; 21 (5): 314-318. ( PubMed, DOI )
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Wang D, Kawashima Y, Nagasawa T, Takeuchi Y, Kojima T, Umeda M, Oda S, Ishikawa I. Elevated serum IgG titer and avidity to Actinobacillus actinomycetemcomitans serotype c in Japanese periodontitis patients. Oral Microbiol Immunol. 2005.06; 20 (3): 172-179. ( PubMed, DOI )
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Umeda M, Miwa Z, Takeuchi Y, Ishizuka M, Huang Y, Noguchi K, Tanaka M, Takagi Y, Ishikawa I. The distribution of periodontopathic bacteria among Japanese children and their parents. J Periodontal Res. 2004.12; 39 (6): 398-404. ( PubMed, DOI )
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Umeda M, Takeuchi Y, Noguchi K, Huang Y, Koshy G, Ishikawa I. Effects of nonsurgical periodontal therapy on the microbiota. Periodontol 2000. 2004; 36 98-120. ( PubMed, DOI )
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Takeuchi Y, Umeda M, Ishizuka M, Huang Y, Ishikawa I. Prevalence of periodontopathic bacteria in aggressive periodontitis patients in a Japanese population. J Periodontol. 2003.10; 74 (10): 1460-1469. ( PubMed, DOI )
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Baehni PC, Takeuchi Y. Anti-plaque agents in the prevention of biofilm-associated oral diseases. Oral Dis. 2003.09; 9 Suppl 1 23-29. ( PubMed )
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Huang Y, Umeda M, Takeuchi Y, Ishizuka M, Yano-Higuchi K, Ishikawa I. Distribution of Bacteroides forsythus genotypes in a Japanese periodontitis population. Oral Microbiol Immunol. 2003.08; 18 (4): 208-214. ( PubMed )
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Sakamoto M, Takeuchi Y, Umeda M, Ishikawa I, Benno Y. Application of terminal RFLP analysis to characterize oral bacterial flora in saliva of healthy subjects and patients with periodontitis. J Med Microbiol. 2003.01; 52 (Pt 1): 79-89. ( PubMed )
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Umeda M, Kobayashi H, Takeuchi Y, Hayashi J, Morotome-Hayashi Y, Yano K, Aoki A, Ohkusa T, Ishikawa I. High prevalence of Helicobacter pylori detected by PCR in the oral cavities of periodontitis patients. J Periodontol. 2003.01; 74 (1): 129-134. ( PubMed, DOI )
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Takeuchi Y, Umeda M, Sakamoto M, Benno Y, Huang Y, Ishikawa I. Treponema socranskii, Treponema denticola, and Porphyromonas gingivalis are associated with severity of periodontal tissue destruction. J Periodontol. 2001.10; 72 (10): 1354-1363. ( PubMed, DOI )
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Sakamoto M, Takeuchi Y, Umeda M, Ishikawa I, Benno Y. Rapid detection and quantification of five periodontopathic bacteria by real-time PCR. Microbiol Immunol. 2001; 45 (1): 39-44. ( PubMed )
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Sakamoto M, Takeuchi Y, Umeda M, Ishikawa I, Benno Y, Nakase T. Detection of Treponema socranskii associated with human periodontitis by PCR. Microbiol Immunol. 1999; 43 (5): 485-490. ( PubMed )
Conference Activities & Talks 【 display / non-display 】
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Shimizu S, Hayashi K, Takeuchi Y, Tanabe G, Churei H, Kobayashi H, Ueno T, Fueki K. Effect of administration of sonicated P. gingivalis on skeletal muscle injury healing using a rat model.. ECSS Paris 2023 2023.07.04 Paris
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Nagai T, Shiba T, Komatsu K, Takashi N, Kobayashi R, Takeuchi Y, Iwata T. Determining the best approach for sequencing analysis of oral microbiota. 2022.10.27 Phoneix, USA
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Tanabe Gen, Hasunuma Tetsuya, Takeuchi Yasuo, Kobayashi Hiroaki, Shimizu Shintaro, Hayashi Kairi, Churei Hiroshi, Sumita Yuka, Suzuki Katsuhiko, Ueno Toshiaki. 口腔粘膜水分による水泳練習中の脱水状態のリアルタイム評価(Real-time assessment of dehydration during swim practice by oral mucosa moisture). The Journal of Physical Fitness and Sports Medicine 2021.11.01
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Tanabe Gen, Hasunuma Tetsuya, Takeuchi Yasuo, Kobayashi Hiroaki, Shimizu Shintaro, Hayashi Kairi, Churei Hiroshi, Sumita Yuka, Suzuki Katsuhiko, Ueno Toshiaki. 口腔粘膜水分による水泳練習中の脱水状態のリアルタイム評価(Real-time assessment of dehydration during swim practice by oral mucosa moisture). The Journal of Physical Fitness and Sports Medicine 2021.11.01
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Komatsu K, Shiba T, Watanabe T, Nemoto T, Koyanagi T, Takeuchi Y, Iwata T. 歯周炎およびインプラント周囲炎の非外科的治療法と細菌叢の分析 7年間の経過観察結果. 日本歯周病学会会誌 2020.12.01
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Komatsu Keiji, Shiba Takahiko, Watanabe Takayasu, Nemoto Takashi, Koyanagi Tatsuro, Takeuchi Yasuo, Iwata Takanori. 歯周炎およびインプラント周囲炎の非外科的治療法と細菌叢の分析 7年間の経過観察結果(Non-surgical treatment and microbiome of periodontitis and peri-implantitis: seven-year follow-up). 日本歯周病学会会誌 2020.12.01
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Ikeda Eri, Shiba Takahiko, Ikeda Yuichi, Suda Wataru, Nakasato Akinori, Takeuchi Yasuo, Azuma Miyuki, Hattori Masahira, Izumi Yuichi. 日本人の健康および病的状態にある歯肉縁下での微生物叢の比較ならびにその微生物叢が歯周炎に関連すると予測される機能において有する役割(Japanese subgingival microbiota in health vs disease and their roles in predicted functions associated with periodontitis). Odontology 2020.04.01
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芝 多佳彦,竹内 康雄,片桐 さやか,駒津 匡二,小柳 達郎,根本 昂,青木 章. オミックス解析による口腔内複合感染症の病因および病態機序の解明. 第83回 口腔病学会学術大会 2018.12.01 東京都文京区
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舩橋 健太,芝 多佳彦,村本 慶子,小川 卓也,竹内 康雄,和泉 雄一,中川 一路,森山 啓司. 口唇口蓋裂患者におけるデンタルプラーク細菌叢のdysbiosisに関する検討. 第83回 口腔病学会学術大会 2018.12.01 東京都文京区
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Harada Y, Sunaga M, Takeuchi Y, Aoki A, Maekawa S, Izumi Y, Kinoshita A.. Effectiveness of improved dental model for training of pocket probing.. The 104th Annual Meeting of American Academy of Periodontology 2018.10.29 Vancouver, Canada
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Aung Nay, 竹内 康雄, 平塚 浩一, 片桐 さやか, 青木 章 . 紫外線LEDの歯周病原細菌への影響. 第30回 日本レーザー歯学会学術大会 2018.10.21 東京
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Aung N, Aoki A, Takeuchi Y, Hiratsuka K, Katagiri S, Kong S, Ammar Shujaa Addin, Meinzer W, Sumi Y, Izumi Y. The effects of different UV LED wavelengths on periodontopathic bacteria. The 16th congress of the World Federation for lasers Dentistry (WFLD) 2018.10.02 Aachen, Germany
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Shiba T, Takagi T, Koyanagi T, Taniguchi Y, Maekawa S, Sawada K, Katagiri S, Takeuchi Y, Aoki A, Izumi Y . The clinical application of the novel diagnosis and treatment flowchart for peri-implantitis: Part 1 clinical application to mild case. EuroPerio9 2018.06.20 Amsterdam, Netherlands
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Sasaki N, Katagiri S, Komazaki R, Watanabe K, Maekawa S, Shiba T, Takeuchi Y, Ohtsu A, Udagawa S, Izumi Y. Sonicated Porphyromonas gingivalis affect non-alcoholic fatty liver disease via glucose metabolism. Europerio 9 2018.06.20 Amsterdam, Netherlands
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Koyanagi T, Taniguchi Y, Takagi T, Shiba T, Sawada K, Takeuchi Y, Aoki A, Izumi Y. The clinical application of a novel diagnosis and treatment flowchart for peri-implantitis: Part 2 - application to moderate cases . EuroPerio9 2018.06.20 Amsterdam, Netherlands
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Taniguchi Y, Koyanagi T, Sawada K, Shiba T, Takagi T, Aoki A, Takeuchi Y, Yamada A, Izumi Y.. The clinical application of the novel diagnosis and treatment flowchart for peri-implantitis: Part 3 clinical application on severe case. EuroPerio9 2018.06.20 Amsterdam, Netherlands
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Katagiri S, Komazaki R, Takahashi H, Maekawa S, Shiba T, Takeuchi Y, Kitajima Y, Ohtsu A, Udagawa S, Sasaki N, Watanabe K, Sato N, Miyasaka N, Eguchi Y, Anzai K, Izumi Y. Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolis.. The 103rd Annual Meeting of American Academy of Periodontology 2017.09.10 Boston, USA
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Maekawa S, Onizuka S, Katagiri S, Komazaki R, Ogura K, Takeuchi Y, Akiyama TM, Nitta H, Iwata T, Izumi Y.. Differential gene expression analysis by RNA-seq: Inflamed periodontal tissue of ligature-induced periodontitis in mice.. The 103rd Annual Meeting of American Academy of Periodontology 2017.09.10 Boston, USA
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Yoshida Y, Churei H, Wada T, Takeuchi Y, Uo M, Ueno T. Antibacterial performance of mouthguard material incorporated with silver-nanoparticles-embedded EVA masterbatch.. FDI World Dental Congress 2017 2017.08.29 Madrid, Spain
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Maekawa S, Katagiri S, Takeuchi Y, Komazaki R, Ohtsu A, Udagawa S, Izumi Y. Bone metabolic microarray analysis of ligature-induced periodontitis in streptozotocin- induced diabetic mice. The 102nd Annual Meeting of American Academy of Periodontology 2016.09.10 San Diego, USA
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Shiba T, Watanabe T, Koyanagi T, Maruyama N, Takeuchi Y, Maruyama F, Izumi Y, Nakagawa I. Functional keystone species enable discrimination of peri-implantitis and periodontitis. The 102nd Annual Meeting of the American Academy of Periodontology in collaboration with the Japanese Society of Periodontology and Japanese Academy of Clinical Periodontology 2016.09.10 San Diego, USA
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渡辺孝康,芝 多佳彦,加地博一,竹内康雄,丸山史人,和泉雄一,中川一路. インプラント周囲炎と歯周炎における細菌叢メタトランスクリプトーム解析. 第58回歯科基礎医学会学術大会 2016.08.25 札幌
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Sugawara Y, Kashimada A, Moriyama K, Baba S, Imai K, Nishikomori R, Motegi M, Takeuchi Y, Morio T. Aicardi-Goutieres and Singleton-Merten overlapping phenotype due to IFIH1 mutation.. The 13th International Congress of Human Genetics 2016.04.06 Kyoto, Japan
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Ikeda E, Takeuchi Y, Suda W, Ikeda Y, Nakasato A, Hattori M, Izumi Y. Pyrosequencing analysis of subgingival microbiota in chronic periodontitis. 45th Annual Meeting and Exhibition of the American Association for Dental Research 2016.03.18 Los angeles, USA
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Shiba T, Watanabe T, Kachi H, Maruyama F, Takeuchi Y, Koyanagi T, Maruyama N, Murase K, Izumi Y, Nakagawa I. Dissimilarities of functional keystone species in co-occurrence network enable discrimination of intractable polymicrobial infectious diseases. SMBE Satellite Workshop on Genome Evolution in Pathogen Transmission and Disease 2016.02.24 Nagano
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Maruyama N, Goda A, Takeuchi Y, Shiba T, Koyanagi T, Izumi Y, Maruyama F, Nakagawa I. Bacterial activity in peri-implantitis and periodontitis. Europerio 8 2015.06.03 London, UK
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Shiba T, Watanabe F, Maruyama F, Takeuchi Y, Koyanagi T, Maruyama N, Nakagawa I, Izumi Y. Inconsistency between abundance of 16S rRNA and mRNA in bacterial community of periodontitis and peri-implantitis. Europerio 8 2015.06.03 London, UK
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Suwannarong W, Tangwanichgapong K, Sumanonta G, Takeuchi Y, Nagasawa T, Izumi Y, Dasanayake A. Periodontopathic bacterial burden in pregnant Thai women. 93rd General Session and Exhibition of the International Association of Dental Research 2015.03.12 Boston, USA
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Ogita M, Tsuchida S, Aoki A, Sato M, Kato S, Sawabe M, Nanbara H, Kobayashi H, Takeuchi Y, Mizutani K, Sasaki Y, Nomura F, Izumi Y.. Increased cell proliferation and differential protein expression induced by low-level Er:YAG laser irradiation in human gingival fibroblast: proteomic analysis.. 14th congress of World Federation for Laser Dentistry 2014.07.02 Paris, France
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Uekubo A, Hiratsuka K, Aoki A, Takeuchi Y, Abiko Y, Izumi Y. The influence of oxygen in blue LED irradiation with rose bengal on the growth of Porphyromonas gingivalis.. 14th congress of World Federation for Laser Dentistry 2014.07.02 Paris, France
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Ye C, Kobayashi H, Katagiri S, Takeuchi Y, Nagasawa T, Izumi Y. Periopathogenic bacteria in oral plaque, saliva and placenta from preterm low birth weight cases. 10th Asia Pacific Society of Periodontology Meeting 2013.09.03 Nara, Japan
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Chui C, Hiratsuka K, Aoki A, Takeuchi Y, Abiko Y, Izumi Y. Effect of blue LED on Porphyromonas gingivalis growth in vitro. 91st General Session and Exhibition of the International Association of Dental Research 2013.03.23 Seattle, USA
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Ogita M, Tsuchida S, Aoki A, Sato M, Sawabe M, Nanbara H, Kobayashi H, Takeuchi Y, Mizutani K, Nomura F, Izumi Y. Proteomic analysis of gingival fibroblasts following low-level Er:YAG laser irradiation.. 91st General Session and Exhibition of the International Association of Dental Research 2013.03.23 Seattle, USA
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Ye C, Kobayashi H, Bharti P, Katagiri S, Takeuchi Y, Nagasawa T, Izumi Y. Periopathogenic bacteria in oral plaque, saliva and placenta from PLBW.. 91st General Session and Exhibition of the International Association of Dental Research 2013.03.23 Seattle, USA
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Chui C, Aoki A, Hiratsuka K, Takeuchi Y, Sasaki Y, Abiko Y, Izumi Y. Antimicrobial effect of a-PDT using high power blue LED and red dye agent on Porphyromonas gingivalis.. The Academy of Laser Dentistry’s 20th Annual Conference and Exhibition 2013.02.07 Palm Springs, USA
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Maruyama N, Maruyama F, Takeuchi Y, Koyanagi T, Nakagawa I, Izumi Y. Comparison of the microbiota in peri-implantitis and periodontitis using pyrosequence.. The 60th Annual Meeting of Japanese Associations for Dental Research 2012.12.14 Niigata, Japan
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Chui C, Hiratsuka K, Aoki A, Takeuchi Y, Abiko Y, Izumi Y. Blue LED inhibits the growth of Porphyromonas gingivalis by suppressing the expression of genes associated with DNA replication and cell division. 第24回日本レーザー歯学会学術大会 2012.12.02 兵庫県神戸市
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Ye C, Katagiri S, Bharti P, Kobayashi H, Takeuchi Y, Nagasawa T, Izumi Y. The role of antibodies against periodontal pathogen on preterm birth. The 98th Annual Meeting of the American Academy of Periodontology 2012.09.29 Los Angeles, USA
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Bharti P, Katagiri1 S, Ye C, Kobayashi H, Takeuchi Y, Nagasawa T, Izumi Y. Expression of CD14, CD16 and CD45 on monocytes from aggressive periodontitis patients.. Europerio 7 2012.06.06 Vienna, Austria
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Takeuchi Y, Nagasawa T, Katagiri S, Kitagawara S, Kobayashi H, Koyanagi T, Izumi Y. Salivary levels of antibacterial peptide (LL-37/hCAP-18) and cotinine in periodontitis patients.. Europerio 7 2012.06.06 Vienna, Austria
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Koyanagi T, Takeuchi Y, Maruyama N, Shiba T, Izumi Y. Analysis of microbiota associated with peri-implantitis.. Europerio 7 2012.06.06 Vienna, Austria
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Ye C, Katagiri S, Bharti P, Kobayashi H, Takeuchi Y, Nagasawa T, Izumi Y. The role of periodontal bacteria on antiphhospholipid syndrome and preterm low birth weight.. Japan-China Dental Conference 2012 2012.04.27 Sichuan, China
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チュー チャントゥーン,青木章,竹内康雄,佐々木好幸,安孫子宜光,和泉雄一. 高出力青色LEDと赤色色素を用いたa-PDTのPorphyromonas gingivalisに対する殺菌効果. 第54回日本歯周病学会秋季学術大会 2011.09.24 山口
Others 【 display / non-display 】
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That's so meta(transcriptomics): distinctive bacterial taxonomic and functional profiles in mouth disease,2021.12
Campus class subject 【 display / non-display 】
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Conservative Dentistry,2014 - Now
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Periodontology Basic concept,2009 - Now
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Supervised Clinical Exposure,2009 - 2022
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Simulation Clinic in Periodontics,2009 - 2022