基本情報

写真a

伊藤 正則(イトウ マサノリ)

ITOH Masanori


職名

教授

研究室住所

市川市国府台2-8-30

研究室電話番号

047-300-7125

研究室FAX番号

047-300-7125

メールアドレス

itohmt.las@tmd.ac.jp

取得学位 【 表示 / 非表示

  • 理学博士  早稲田大学

経歴(学内) 【 表示 / 非表示

  • 2010年04月
    -
    2022年03月
    東京医科歯科大学 教養部 自然科学系 生物学 教授
  • 2022年04月
    -
    現在
    東京医科歯科大学 統合教育機構 教養教育部門 教授

経歴(学外) 【 表示 / 非表示

  • 2010年04月
    -
    現在
    聖マリアンナ医科大学 客員教授

所属学協会 【 表示 / 非表示

  • 日本動物学会

  • 日本生殖内分泌学会

委員歴 【 表示 / 非表示

  • 日本動物学会 関東支部
  • 2007年
    -
    現在
    日本生殖内分泌学会 評議員

研究分野 【 表示 / 非表示

  • 形態、構造

 

研究テーマ 【 表示 / 非表示

  • 卵母細胞の形成・成熟機構

  • 本能行動の脳制御機構

競争的資金等の研究課題 【 表示 / 非表示

  • 卵母細胞によるメラトニン合成とその意義

    文部科学省/日本学術振興会 : 2010年 - 2012年

  • 原発性卵巣不全関連因子であるFMRIタンパク質の機能解析

    文部科学省/日本学術振興会

論文・総説 【 表示 / 非表示

  1. Noriyuki Takahashi, Wataru Tarumi, Naomi Hamada, Bunpei Ishizuka, Masanori T Itoh. Cresyl Violet Stains Mast Cells Selectively: Its Application to Counterstaining in Immunohistochemistry. Zool. Sci.. 2017.04; 34 (2): 147-150. ( PubMed, DOI )

  2. Noriyuki Takahashi, Wataru Tarumi, Masanori T Itoh, Bunpei Ishizuka. The Stage- and Cell Type-Specific Localization of Fragile X Mental Retardation Protein in Rat Ovaries. Reprod Sci. 2015.12; 22 (12): 1524-1529. ( PubMed, DOI )

  3. Wataru Tarumi, Masanori T Itoh, Nao Suzuki. Effects of 5alpha-dihydrotestosterone and 17beta-estradiol on the mouse ovarian follicle development and oocyte maturation. PLoS ONE. 2014.06; 9 (6): e99423. ( PubMed, DOI )

  4. Kenichiro Sakaguchi, Masanori T Itoh, Noriyuki Takahashi, Wataru Tarumi, Bunpei Ishizuka. The rat oocyte synthesises melatonin. Reprod. Fertil. Dev.. 2013.12; 25 (4): 674-682. ( PubMed, DOI )

  5. Wataru Tarumi, Sanae Tsukamoto, Yuki Okutsu, Noriyuki Takahashi, Toshitaka Horiuchi, Masanori T Itoh, Bunpei Ishizuka. Androstenedione induces abnormalities in morphology and function of developing oocytes, which impairs oocyte meiotic competence. Fertil. Steril.. 2012.02; 97 (2): 469-476. ( PubMed, DOI )

  6. Bunpei Ishizuka, Naoki Okamoto, Naomi Hamada, Yodo Sugishita, Juichiro Saito, Noriyuki Takahashi, Tsutomu Ogata, Masanori T Itoh. Number of CGG repeats in the FMR1 gene of Japanese patients with primary ovarian insufficiency. Fertil. Steril.. 2011.11; 96 (5): 1170-1174. ( PubMed, DOI )

  7. Nobuhito Yoshioka, Noriyuki Takahashi, Wataru Tarumi, Masanori T Itoh, Bunpei Ishizuka. Gonadotropins up-regulate the expression of enolase 2, but not enolase 1, in the rat ovary. Endocr. J.. 2011.08; 58 (11): 941-948. ( PubMed )

  8. Okutsu Y, Itoh MT, Takahashi N, Ishizuka B. Exogenous androstenedione induces formation of follicular cysts and premature luteinization of granulosa cells in the ovary. Fertil Steril. 2010.02; 93 (3): 927-935. ( PubMed, DOI )

  9. Takahashi N, Itoh MT, Ishizuka B. Human chorionic gonadotropin induces nestin expression in endothelial cells of the ovary via vascular endothelial growth factor signaling. Endocrinology. 2008.01; 149 (1): 253-260. ( PubMed, DOI )

  10. Itoh MT, Takahashi N, Abe M, Shimizu K. Expression and cellular localization of melatonin-synthesizing enzymes in the rat lens. J Pineal Res. 2007.01; 42 (1): 92-96. ( PubMed, DOI )

  11. Itoh MT, Hosaka T, Takahashi N, Ishizuka B. Expression of luteinizing hormone/chorionic gonadotropin receptor in the rat pineal gland. J Pineal Res. 2006.08; 41 (1): 35-41. ( PubMed, DOI )

  12. Itoh MT, Ishizuka B. alpha1-Adrenergic receptor in rat ovary: presence and localization. Mol Cell Endocrinol. 2005.08; 240 (1-2): 58-63. ( PubMed, DOI )

  13. Murakami S, Itoh MT. Removal of both antennae influences the courtship and aggressive behaviors in male crickets. J Neurobiol. 2003.10; 57 (1): 110-118. ( PubMed, DOI )

  14. Kobayashi Y, Itoh MT, Kondo H, Okuma Y, Sato S, Kanishi Y, Hamada N, Kiguchi K, Ishizuka B. Melatonin binding sites in estrogen receptor-positive cells derived from human endometrial cancer. J Pineal Res. 2003.09; 35 (2): 71-74. ( PubMed )

  15. Itoh MT, Hosaka T, Mimuro T, Hamada N, Ishizuka B. Gonadotropin-releasing hormone increases melatonin release in the pineal gland of the female rat in vitro. Horm Metab Res. 2003.03; 35 (3): 153-157. ( PubMed, DOI )

  16. Masanori T. Itoh, Tukasa Nakamura. Photoperiod conditions influence fecal estradiol levels in females of migratory reed bunting Emberiza sscoeniclus and non-migratory meadow bunting Emberiza cioides Journal of the Yamashina Institute for Ornithology. 2002.10; 34 (1): 1-8.

  17. Hosaka T, Mimuro T, Hamada N, Itoh MT, Ishizuka B. Stimulatory effects of LH on release of melatonin and activities of its synthesizing enzymes NAT and HIOMT in organ-cultured pineal glands of female rats. Horm Metab Res. 2002.08; 34 (8): 441-445. ( PubMed, DOI )

  18. Itoh MT, Murakami S. The effect of female wings on male courtship behavior in the cricket Gryllus bimaculatus. Naturwissenschaften. 2002.05; 89 (5): 230-232. ( PubMed )

  19. Murakami S, Itoh MT. Effects of aggression and wing removal on brain serotonin levels in male crickets, Gryllus bimaculatus. J Insect Physiol. 2001.11; 47 (11): 1309-1312. ( PubMed )

  20. Itoh MT, Sumi Y. Circadian clock controlling egg hatching in the cricket (Gryllus bimaculatus). J Biol Rhythms. 2000.06; 15 (3): 241-245. ( PubMed )

  21. Abe M, Itoh MT, Miyata M, Shimizu K, Sumi Y. Circadian rhythm of serotonin N -acetyltransferase activity in rat lens. Exp Eye Res. 2000.06; 70 (6): 805-808. ( PubMed, DOI )

  22. Ishizuka B, Fusama S, Hirai K, Hosaka T, Hamada N, Amemiya A, Itoh MT. Melatonin secretion from organ-cultured pineal glands of rats: modulation by gonadectomy and gonadotropin-releasing hormone agonist administration. Eur J Endocrinol. 2000.04; 142 (4): 387-392. ( PubMed )

  23. Itoh MT, Igarashi J. Circadian rhythm of serotonin levels in planarians. Neuroreport. 2000.02; 11 (3): 473-476. ( PubMed )

  24. Ishizuka B, Kuribayashi Y, Murai K, Amemiya A, Itoh MT. The effect of melatonin on in vitro fertilization and embryo development in mice. J Pineal Res. 2000.01; 28 (1): 48-51. ( PubMed )

  25. Itoh MT, Ishizuka B, Kuribayashi Y, Abe Y, Sumi Y. Noradrenaline concentrations in human preovulatory follicular fluid exceed those in peripheral plasma. Exp Clin Endocrinol Diabetes. 2000; 108 (8): 506-509. ( PubMed, DOI )

  26. Sumi Y, Itoh MT, Yoshida M, Akama Y. Highly sensitive chelating agents for histochemical staining of rare earth metals. Histochem Cell Biol. 1999.08; 112 (2): 179-182. ( PubMed )

  27. Itoh MT, Ishizuka B, Kuribayashi Y, Amemiya A, Sumi Y. Melatonin, its precursors, and synthesizing enzyme activities in the human ovary. Mol Hum Reprod. 1999.05; 5 (5): 402-408. ( PubMed )

  28. Itoh MT, Shinozawa T, Sumi Y. Circadian rhythms of melatonin-synthesizing enzyme activities and melatonin levels in planarians. Brain Res. 1999.05; 830 (1): 165-173. ( PubMed )

  29. Abe M, Itoh MT, Miyata M, Ishikawa S, Sumi Y. Detection of melatonin, its precursors and related enzyme activities in rabbit lens. Exp Eye Res. 1999.02; 68 (2): 255-262. ( PubMed, DOI )

  30. Itoh MT, Sumi Y. Circadian clock controlling arylalkylamine N-acetyltransferase-like activity in the cricket (Gryllus bimaculatus) egg. Brain Res. 1998.07; 799 (1): 172-175. ( PubMed )

  31. Itoh MT, Sumi Y. Melatonin and serotonin N-acetyltransferase activity in developing eggs of the cricket Gryllus bimaculatus. Brain Res. 1998.01; 781 (1-2): 90-99. ( PubMed )

  32. Sumi Y, Itoh MT, Yoshida M, Suzuki T. Histochemical staining of chromium with 2-(8-quinolylazo)-4,5-di-p-tolylimidazole. Eur J Histochem. 1998; 42 (4): 271-276. ( PubMed )

  33. Itoh MT, Ishizuka B, Kudo Y, Fusama S, Amemiya A, Sumi Y. Detection of melatonin and serotonin N-acetyltransferase and hydroxyindole-O-methyltransferase activities in rat ovary. Mol Cell Endocrinol. 1997.12; 136 (1): 7-13. ( PubMed )

  34. Itoh MT, Nomura T, Sumi Y. Hydroxyindole-O-methyltransferase activity in the silkworm (Bombyx mori). Brain Res. 1997.08; 765 (1): 61-66. ( PubMed )

  35. Itoh MT, Hattori A, Sumi Y. Hydroxyindole-O-methyltransferase activity assay using high-performance liquid chromatography with fluorometric detection: determination of melatonin enzymatically formed from N-acetylserotonin and S-adenosyl-L-methionine. J Chromatogr B Biomed Sci Appl. 1997.04; 692 (1): 217-221. ( PubMed )

  36. Tsukasa Nakamura, Masanori Itoh, Nobuyuki yamaguchi, kaoru kubokawa, Susumu Ishii. Influence of photoperiod duration on fecal androgen content in migratory reed bunting Emberiza schoeniclus and non-migratory meadow bunting Emberiza cioides males Japan Journal of Ornithology. 1996.12; 45 (1): 159-165.

  37. Sumi Y, Itoh MT, Muraki T, Suzuki T. Histochemical staining of cadmium with 2-(8-quinolylazo)-4,5-diphenylimidazole. Histochem Cell Biol. 1996.08; 106 (2): 223-227. ( PubMed )

  38. M T Itoh, A Hattori, T Nomura, Y Sumi, T Suzuki. Melatonin and arylalkylamine N-acetyltransferase activity in the silkworm, Bombyx mori. Mol. Cell. Endocrinol.. 1995.11; 115 (1): 59-64. ( PubMed )

  39. Itoh MT, Hattori A, Sumi Y, Suzuki T. Day-night changes in melatonin levels in different organs of the cricket (Gryllus bimaculatus). J Pineal Res. 1995.04; 18 (3): 165-169. ( PubMed )

  40. Atsuhiko Hattori, Hiro Migitaka, Masayuki Iigo, Masanori T. Itoh, Koji Yamamoto, Ritsuko Ohtani-Kaneko, Masayuki Hara, Takuro Suzuki, Russel J. Reiter. Idetification of melatonin in plants and its effects on plasma melatonin levels and binding to melatonin receptors in vertebrates Biochemistry and Molecular Biology International. 1995.03; 35 (3): 627-634.

  41. Masanori T. Itoh, atsuhiko Hattori, Yawara Sumi, Takuro Suzuki. Identification of melatonin in different organs of the cricket, Gryllus bimaculatus Zoological Science. 1994.03; 11 (1): 577-581.

  42. S Ishii, M Itoh. Amplexus induces surge of luteinizing hormone in male toads, Bufo japonicus. Gen. Comp. Endocrinol.. 1992.04; 86 (1): 34-41. ( PubMed )

  43. M Itoh, S Ishii. Changes in plasma levels of gonadotropins and sex steroids in the toad, Bufo japonicus, in association with behavior during the breeding season. Gen. Comp. Endocrinol.. 1990.12; 80 (3): 451-464. ( PubMed )

  44. M Itoh, M Inoue, S Ishii. Annual cycle of pituitary and plasma gonadotropins and plasma sex steroids in a wild population of the toad, Bufo japonicus. Gen. Comp. Endocrinol.. 1990.05; 78 (2): 242-253. ( PubMed )

  45. Koji Takada, Masanori Itoh, Hiroshi Nishio, Susumu Ishii. Purification of toad (Bufo japonicus) gonadotropins and development of their homologous radioimmunoassays Zoological Science. 1989.12; 6 (1): 963-974.

  46. 鷲見 和、伊藤 正則、鈴木 慶二. キノリルアゾフェニルイミダゾールのカドミウムに対する組織化学的染色性とアミンによる妨害金属の封鎖 Biomedical Research on Trace Elements. 1995.06; 6 (1): 213-214.

▼全件表示

書籍等出版物 【 表示 / 非表示

  1. 末光 隆志. 動物の事典. 朝倉書店, 2020.11 生殖腺 (ISBN : 8-4-17166-2C3545)

  2. 石塚 文平、鈴木 秋悦. 生殖卵巣学. 医師薬出版株式会社, 2011.09 卵巣の解剖・組織学 (ISBN : 978-4-263-73138-3)

講演・口頭発表等 【 表示 / 非表示

  1. Takahashi N, Suzuki N, Itoh MT, ishizuka B. The involvement of neurofilament heavy chain phosphorylation in the maturation and degeneration of rat oocytes.. The 22nd International Congress of Zoology Joint Events The 87th meeting of Zoological Society of Japan 2016.09.08 那覇

  2. 伊藤正則、高橋則行、樽見航、石塚文平. ラット卵母細胞におけるFMRPの発現. 第152回関東生殖医学会 2018.07.15 東京

  3. 高橋 則行、伊藤 正則、樽見 航、鈴木 直、石塚 文平. ラット卵巣におけるTauの局在と発現誘導. 日本動物学会第88回大会 2017.09.21 富山

  4. 伊藤 正則、高橋 則行、樽見 航. ラット下垂体におけるLH/hCG受容体の発現. 日本動物学会第88回大会 2017.09.21 富山

受賞学術賞 【 表示 / 非表示

  • Zoological Science Award,日本動物学会,2002年10月

 

担当授業科目(学内) 【 表示 / 非表示

  • 生物学(細胞・遺伝子)

  • 生物学(構造・機能)

  • 生物学実験

  • 科学基礎実験

  • 生命科学基礎(生物)

  • 生命科学(人体の生物学)

  • サイエンスPBL

  • サイエンスPBL入門

  • 主題別ⅠⅡ(生物間のコミュニケーション)

  • 主題別ⅠⅡ(環境への適応)

  • ウニの発生と海産生物の観察実習

  • 教養総合講座(基礎ゼミ)

▼全件表示

担当授業科目(学外) 【 表示 / 非表示

  • 生物学Ⅰ・Ⅱ,国立大学法人東京藝術大学