Personnel Information

写真a

FUJIKAWA Taro


Job title

Assistant Professor

Laboratory Address

Tokyo Medical & Dental University, Otolaryngology

Laboratory Phone number

+81-3-5803-5308

Laboratory Fax number

+81-3-3813-2134

Research Areas, Keywords

Otology, Hereditary hearing loss, Age-related hearing loss, Noise-induced hearing loss, Hair cell synapse

Graduating School 【 display / non-display

  • Tokyo Medical and Dental University, Faculty of Medicine, 2003, Graduated

Degree 【 display / non-display

  • PhD, Tokyo Medical and Dental University

Campus Career 【 display / non-display

  • 2015.10
    -
    2018.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Cognitive and Behavioral Medicine, Otorhinolaryngology, Assistant Professor
  • 2010.02
    -
    2010.08
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Maxillofacial and Neck Reconstruction, Head and Neck Surgery, Assistant Professor
  • 2018.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Cognitive and Behavioral Medicine, Otorhinolaryngology, Assistant Professor

External Career 【 display / non-display

  • 2010.09
    -
    2013.04
    National Institutes of Health, National Institute of Deafness and Communication Disorder, Visiting Fellow
  • 2013.06
    -
    2015.09
    Saitama Cancer Center, Head and Neck Surgery,

Academic Society Affiliations 【 display / non-display

  • Oto-Rhino-Laryngological Society of Japan

  • Otology Japan

  • Audiology Japan

  • Association for Research in Otolaryngology

  • Japan Society For Equilibrium Research

  • The Japan Society of Human Genetics

  • Japan Society for Head and Neck Surgery

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Research Areas 【 display / non-display

  • Otorhinolaryngology

Qualification Acquired 【 display / non-display

  • Doctor

 

Research Theme 【 display / non-display

  • Hereditary hearing loss, 2006 - Now

  • Hair cell synapses, 2009 - Now

  • Synaptopathy in age-related hearing loss, 2013 - Now

Published Papers & Misc 【 display / non-display

  1. Kurata N, Kawashima Y, Ito T, Fujikawa T, Nishio A, Honda K, Kanai Y, Terasaki M, Endo I, Tsutsumi T. Advanced Magnetic Resonance Imaging Sheds Light on the Distinct Pathophysiology of Various Types of Acute Sensorineural Hearing Loss. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2023.08; 44 (7): 656-663. ( PubMed, DOI )

  2. Watanabe H, Ito T, Aoki N, Bai J, Honda K, Kawashima Y, Fujikawa T, Ikeda T, Tsutsumi T. Quantitative analysis and correlative evaluation of video-oculography, micro-computed tomography, and histopathology in Pendrin-null mice. Neurobiology of disease. 2023.07; 183 106194. ( PubMed, DOI )

  3. Fujikawa T, Tanimoto K, Kawashima Y, Ito T, Honda K, Takeda T, Sonobe A, Aoki N, Bai J, Tsutsumi T. Cholesteatoma has an altered microbiota with a higher abundance of Staphylococcus species. Laryngoscope investigative otolaryngology. 2022.12; 7 (6): 2011-2019. ( PubMed, DOI )

  4. Yamazaki A, Ito T, Sugimoto M, Yoshida S, Honda K, Kawashima Y, Fujikawa T, Fujii Y, Tsutsumi T. Patient-specific virtual and mixed reality for immersive, experiential anatomy education and for surgical planning in temporal bone surgery. Auris, nasus, larynx. 2021.12; 48 (6): 1081-1091. ( PubMed, DOI )

  5. Takeda Takamori, Ito Taku, Onishi Iichiroh, Yokomura Masaru, Kawashima Yoshiyuki, Fujikawa Taro, Tsutsumi Takeshi. デノスマブで誘発された外耳道の骨壊死(Denosumab-induced osteonecrosis of external auditory canal) Auris・Nasus・Larynx. 2021.12; 48 (6): 1199-1203. ( ichushi )

  6. Yamazaki Ayame, Ito Taku, Sugimoto Maki, Yoshida Soichiro, Honda Keiji, Kawashima Yoshiyuki, Fujikawa Taro, Fujii Yasuhisa, Tsutsumi Takeshi. 没入体験式の解剖教育への利用および側頭骨手術時の手術計画への利用を目的とする、患者ごとに構築した仮想現実および複合現実(Patient-specific virtual and mixed reality for immersive, experiential anatomy education and for surgical planning in temporal bone surgery) Auris・Nasus・Larynx. 2021.12; 48 (6): 1081-1091. ( ichushi )

  7. Ito T, Fujikawa T, Honda K, Makabe A, Watanabe H, Bai J, Kawashima Y, Miwa T, Griffith AJ, Tsutsumi T. Cochlear Pathomorphogenesis of Incomplete Partition Type II in Slc26a4-Null Mice. Journal of the Association for Research in Otolaryngology : JARO. 2021.12; 22 (6): 681-691. ( PubMed, DOI )

  8. Fujikawa T, Honda K, Ito T, Kishino M, Kimura N, Umezawa N, Hirano M, Aoki N, Kawashima Y, Tsutsumi T. Enhanced fallopian canal as a potential marker for temporal bone vasculitis. Laryngoscope investigative otolaryngology. 2020.12; 5 (6): 1168-1175. ( PubMed, DOI )

  9. Takeda T, Ito T, Onishi I, Yokomura M, Kawashima Y, Fujikawa T, Tsutsumi T. Denosumab-induced osteonecrosis of external auditory canal. Auris, nasus, larynx. 2020.07; ( PubMed, DOI )

  10. Makabe A, Kawashima Y, Sakamaki Y, Maruyama A, Fujikawa T, Ito T, Kurima K, Griffith AJ, Tsutsumi T. Systemic Fluorescent Gentamicin Enters Neonatal Mouse Hair Cells Predominantly Through Sensory Mechanoelectrical Transduction Channels. Journal of the Association for Research in Otolaryngology : JARO. 2020.03; ( PubMed, DOI )

  11. Maruyama A, Kawashima Y, Fujikawa T, Makabe A, Ito T, Takeda T, Tsutsumi T. Potential Confounding Factors May Influence the Association Between Configurations of the Vertebrobasilar System and the Incidence of Idiopathic Sudden Sensorineural Hearing Loss and Canal Paresis. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2020.03; ( PubMed, DOI )

  12. Ito T, Kawashima Y, Fujikawa T, Honda K, Makabe A, Kitamura K, Tsutsumi T. Rapid screening of copy number variations in <i>STR</i>C by droplet digital PCR in patients with mild-to-moderate hearing loss. Human genome variation. 2019; 6 41. ( PubMed, DOI )

  13. Ito Taku, Kawashima Yoshiyuki, Fujikawa Taro, Honda Keiji, Makabe Ayane, Kitamura Ken, Tsutsumi Takeshi. Rapid screening of copy number variations in STRC by droplet digital PCR in patients with mild-to-moderate hearing loss(和訳中) Human Genome Variation. 2019; 6 1 of 6-6 of 6. ( ichushi )

  14. Takeda T, Kawashima Y, Hirai C, Makabe A, Ito T, Fujikawa T, Yamamoto K, Maruyama A, Tsutsumi T. Vestibular Dysfunction in Patients With Superficial Siderosis of the Central Nervous System. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2018.07; 39 (6): e468-e474. ( PubMed, DOI )

  15. Kobayashi M, Miyagawa M, Nishio SY, Moteki H, Fujikawa T, Ohyama K, Sakaguchi H, Miyanohara I, Sugaya A, Naito Y, Morita SY, Kanda Y, Takahashi M, Ishikawa K, Nagano Y, Tono T, Oshikawa C, Kihara C, Takahashi H, Noguchi Y, Usami SI. WFS1 mutation screening in a large series of Japanese hearing loss patients: Massively parallel DNA sequencing-based analysis. PloS one. 2018.03; 13 (3): e0193359. ( PubMed, DOI )

  16. Noguchi Y, Takahashi M, Ito T, Fujikawa T, Kawashima Y, Kitamura K. Delayed restoration of maximum speech discrimination scores in patients with idiopathic sudden sensorineural hearing loss Auris Nasus Larynx. 2016.05; 43 (5): 495-500. ( PubMed, DOI )

  17. Atsumori Hamahata, Takeshi Beppu, Taro Fujikawa, Takashi Yamaki, Hiroyuki Sakurai. Usefulness of a Reconstructive Method for Oropharyngeal Defect Including the Larger Soft Palate with the Bent Anterolateral Thigh Flap. Journal of Reconstructive Microsurgery. 2015.11; 31 (9): 688-691. ( PubMed, DOI )

  18. Kiyoto Kurima, Seham Ebrahim, Bifeng Pan, Miloslav Sedlacek, Prabuddha Sengupta, Bryan A Millis, Runjia Cui, Hiroshi Nakanishi, Taro Fujikawa, Yoshiyuki Kawashima, Byung Yoon Choi, Kelly Monahan, Jeffrey R Holt, Andrew J Griffith, Bechara Kachar. TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia. Cell Reports. 2015.09; 12 (10): 1606-1617. ( PubMed, DOI )

  19. Taro Fujikawa, Ronald S Petralia, Tracy S Fitzgerald, Ya-Xian Wang, Bryan Millis, José Andrés Morgado-Díaz, Ken Kitamura, Bechara Kachar. Localization of kainate receptors in inner and outer hair cell synapses. Hearing Research. 2014.08; 314 20-32. ( PubMed, DOI )

  20. Denise Yan, Yan Zhu, Tom Walsh, Dinghua Xie, Huijun Yuan, Asli Sirmaci, Taro Fujikawa, Ann Chi Yan Wong, Tze L Loh, Lilin Du, M'hamed Grati, Srdjan M Vlajkovic, Susan Blanton, Allen F Ryan, Zheng-Yi Chen, Peter R Thorne, Bechara Kachar, Mustafa Tekin, Hong-Bo Zhao, Gary D Housley, Mary-Claire King, Xue Z Liu. Mutation of the ATP-gated P2X(2) receptor leads to progressive hearing loss and increased susceptibility to noise. Proc. Natl. Acad. Sci. U.S.A.. 2013.02; 110 (6): 2228-2233. ( PubMed, DOI )

  21. Taro Fujikawa, Yoshihiro Noguchi, Taku Ito, Masatoki Takahashi, Ken Kitamura. Additional heterozygous 2507A>C mutation of WFS1 in progressive hearing loss at lower frequencies. Laryngoscope. 2010.01; 120 (1): 166-171. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  1. 白 静, 伊藤 卓, 川島 慶之, 藤川 太郎, 本田 圭司, 渡邊 浩基, 倉田 奈都子, 堤 剛. C57BL/6Jマウスを用いた、出生後の耳石発生に関するEx VivoでのマイクロCT分析(Ex Vivo Micro-CT Analysis of Postnatal Otoconia Development in C57BL/6J Mice). 日本耳科学会総会・学術講演会抄録集 2022.10.01

  2. 白 静, 伊藤 卓, 川島 慶之, 藤川 太郎, 本田 圭司, 渡邊 浩基, 倉田 奈都子, 堤 剛. マウスの生後における耳嚢石灰化過程のマイクロCTによる可視化(Calcification Process of the Otic Capsule in Postnatal Stage of Mice Visualized with Micro-CT). 日本耳科学会総会・学術講演会抄録集 2021.10.01

  3. Takamori Takeda, Taro Fujikawa他. GluD1 Deficiency Causes Progressive High-Frequency Hearing Loss and Insufficient Efferent Synapse Formation on Outer Hair Cells. 42nd annual meeting of ARO 2019.02.12

  4. Taku Ito, Taro Fujikawa他. Correlation of Micro CT and Histopathology in SLC26A-Null Mice Unveils the Cochlear Pathogenesis of Incomplete Partition Type II. 42nd annual meeting of ARO 2019.02.10

  5. Taro Fujikawa, et al.. Malnutrition and Delirium Interrupt Postoperative Swallowing Improvement in Elderly Patients with Head and Neck Cancer. The 14th Taiwan-Japan Conference on Otolaryngology-Head and Neck Surgery 2017.12.01