Personnel Information



Job title


Birth date


Mail Address

Graduating School 【 display / non-display

  • Kyoto University, Faculty of Engineering, 1981, Graduated

  • Kyoto Prefectural University of Medicine, Faculty of Medicine, 1992, Graduated

Graduate School 【 display / non-display

  • Kyoto University, Graduate School, Division of Engineering, chemical enginearing, Master's Course, 1983, Completed

Degree 【 display / non-display

  • M.D., Ph.D, Kyoto Prefectural University of Medicine

Campus Career 【 display / non-display

  • 2007.09
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Public Health, Forensic Medicine, Professor
  • 2018.04
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Public Health, Forensic Medicine, Professor

Academic Society Affiliations 【 display / non-display

  • Japanese Society of Legal Medicine

Research Areas 【 display / non-display

  • Forensics medicine

Qualification Acquired 【 display / non-display

  • Doctor


Research Theme 【 display / non-display

  • Toxicology

Published Papers & Misc 【 display / non-display

  1. Shuheng Wen, Kana Unuma, Yohsuke Makino, Hiroki Mori, Koichi Uemura. Fatal consequence after MiraDry® treatment: Necrotizing fasciitis complicated with streptococcal toxic shock syndrome. Leg Med (Tokyo). 2022.05; 58 102095. ( PubMed, DOI )

  2. Shuheng Wen, Toshihiko Aki, Takeshi Funakoshi, Kana Unuma, Koichi Uemura. Role of Mitochondrial Dynamics in Cocaine's Neurotoxicity. Int J Mol Sci. 2022.05; 23 (10): ( PubMed, DOI )

  3. Toshihiko Aki, Takeshi Funakoshi, Kana Unuma, Koichi Uemura. Inverse regulation of GSDMD and GSDME gene expression during LPS-induced pyroptosis in RAW264.7 macrophage cells. Apoptosis. 2022.01; ( PubMed, DOI )

  4. Toshihiko Aki, Kana Unuma, Koichi Uemura. The Role of Peroxiredoxins in the Regulation of Sepsis. Antioxidants (Basel). 2022.01; 11 (1): ( PubMed, DOI )

  5. Shuheng Wen, Kana Unuma, Takeshi Funakoshi, Toshihiko Aki, Koichi Uemura. Altered cardiac mitochondrial dynamics and biogenesis in rat after short-term cocaine administration. Sci Rep. 2021.12; 11 (1): 24129. ( PubMed, DOI )

  6. Shuheng Wen, Kana Unuma, Ryo Watanabe, Yohsuke Makino, Koichi Uemura. Forensic evaluation of fatal-suffocating retropharyngeal haematoma secondary to cervical fractures: Report of two cases. J Forensic Leg Med. 2021.11; 85 102274. ( PubMed, DOI )

  7. Toshihiko Aki, Koichi Uemura. Cell Death and Survival Pathways Involving ATM Protein Kinase. Genes (Basel). 2021.10; 12 (10): ( PubMed, DOI )

  8. Atsushi Yamada, Kana Unuma, Nobutaka Arai, Osamu Kitamura, Koichi Uemura. Inappropriate diet and fatal malnutrition in a 10-year-old child fed only infant formula throughout life: Novel pathological diagnostic criterion for starvation via lipophagy. Forensic Sci Int. 2021.07; 325 110896. ( PubMed, DOI )

  9. Kana Unuma, Yohsuke Makino, Kouhei Yamamoto, Shinya Hattori, Nobutaka Arai, Kentaro Sakai, Masanobu Kitagawa, Koichi Uemura, Hirokazu Kanegane. Fatal intracranial hemorrhage due to infantile acute lymphoblastic leukemia mimicking abusive head trauma. J Forensic Sci. 2021.07; ( PubMed, DOI )

  10. Momoka Ota, Takeshi Funakoshi, Toshihiko Aki, Kana Unuma, Koichi Uemura. Oxcarbazepine induces mitotic catastrophe and apoptosis in NRK-52E proximal tubular cells. Toxicol Lett. 2021.07; 350 240-248. ( PubMed, DOI )

  11. Shuheng Wen, Kana Unuma, Ryo Watanabe, Koichi Uemura. Diagnosis by forensic autopsy of cannula malposition resulting in fatal tension pneumothorax after attempted percutaneous tracheostomy: A short communication. J Forensic Leg Med. 2021.05; 81 102177. ( PubMed, DOI )

  12. Tatsuhiko Murata, Kanako Noritake, Toshihiko Aki, Koichi Uemura. Possible roles of AMPK and macropinocytosis in the defense responses against Δ 9-THC toxicity on HL-1 cardiomyocytes Toxicol Rep. 2021; 8 980-987. ( PubMed, DOI )

  13. Moeka Nomura, Kana Unuma, Toshihiko Aki, Koichi Uemura. Sustained splenic contraction after daily cocaine administration in rats. PLoS One. 2021; 16 (6): e0252853. ( PubMed, DOI )

  14. Midori Nagai, Koichi Sakurada, Kazuhiko Imaizumi, Yoshinori Ogawa, Motohiro Uo, Takeshi Funakoshi, Koichi Uemura. Evaluation of Parameters for Estimating the Postmortem Interval of Skeletal Remains Using Bovine Femurs: A Pilot Study. Diagnostics (Basel). 2020.12; 10 (12): ( PubMed, DOI )

  15. Tetsushi Kitayama, Takashi Fukagawa, Haruhiko Watahiki, Yusuke Mita, Koji Fujii, Kana Unuma, Koichi Sakurada, Koichi Uemura, Kazumasa Sekiguchi, Natsuko Mizuno. Evaluation of Rapid DNA system for buccal swab and disaster victim identification samples. Leg Med (Tokyo). 2020.09; 46 101713. ( PubMed, DOI )

  16. Kana Unuma, Ryo Watanabe, Naho Hirayama, Koichi Uemura. Autopsy Identification of Viable Mycobacterium Tuberculosis in the Lungs of a Markedly Decomposed Body. J. Forensic Sci.. 2020.08; ( PubMed, DOI )

  17. Toshihiko Aki, Takeshi Funakoshi, Kanako Noritake, Kana Unuma, Koichi Uemura. Extracellular glucose is crucially involved in the fate decision of LPS-stimulated RAW264.7 murine macrophage cells. Sci Rep. 2020.06; 10 (1): 10581. ( PubMed, DOI )

  18. Shuheng Wen, Toshihiko Aki, Kana Unuma, Koichi Uemura. Chemically Induced Models of Parkinson's Disease: History and Perspectives for the Involvement of Ferroptosis. Front Cell Neurosci. 2020; 14 581191. ( PubMed, DOI )

  19. Takeshi Funakoshi, Mako Furukawa, Toshihiko Aki, Koichi Uemura. Repeated exposure of cocaine alters mitochondrial dynamics in mouse neuroblastoma Neuro2a. Neurotoxicology. 2019.09; ( PubMed, DOI )

  20. Kana Unuma, Toshihiko Aki, Ayaka Yamashita, Ayaka Yoshikawa, Koichi Uemura. Hydrogen sulfide donor NaHS causes bronchitis with enhanced respiratory secretion in rats. J Toxicol Sci. 2019; 44 (2): 107-112. ( PubMed, DOI )

  21. Toshihiko Aki, Kana Unuma, Kanako Noritake, Naho Hirayama, Takeshi Funakoshi, Koichi Uemura. Formation of high molecular weight p62 by CORM-3. PLoS ONE. 2019; 14 (1): e0210474. ( PubMed, DOI )

  22. Kana Unuma, Yohsuke Makino, Yoshiyuki Sasaki, Hirotaro Iwase, Koichi Uemura.. Presepsin: A potential superior diagnostic biomarker for the postmortem differentiation of sepsis based on the Sepsis-3 criteria Forensic Science International. 2019; 299 17-20. ( DOI )

  23. Kana Unuma, Ayaka Yoshikawa, Toshihiko Aki, Koichi Uemura. Increased circulating peroxiredoxin-4 in sepsis model rats involves secretion from hepatocytes and is mitigated by GYY4137. J Toxicol Pathol. 2019; 32 (4): 305-310. ( PubMed, DOI )

  24. Toshihiko Aki, Kana Unuma, Kanako Noritake, Hatsumi Kurahashi, Takeshi Funakoshi, Koichi Uemura. Interaction of carbon monoxide-releasing ruthenium carbonyl CORM-3 with plasma fibronectin. Toxicol In Vitro. 2018.03; 50 201-209. ( PubMed, DOI )

  25. Naho Hirayama, Toshihiko Aki, Takeshi Funakoshi, Kanako Noritake, Kana Unuma, Koichi Uemura. Necrosis in human neuronal cells exposed to paraquat. J Toxicol Sci. 2018.03; 43 (3): 193-202. ( PubMed, DOI )

  26. Kana Unuma, Toshihiko Aki, Suguru Nagano, Ryo Watanabe, Koichi Uemura. The down-regulation of cardiac contractile proteins underlies myocardial depression during sepsis and is mitigated by carbon monoxide. Biochem. Biophys. Res. Commun.. 2018.01; 495 (2): 1668-1674. ( PubMed, DOI )

  27. Toshihiko Aki, Kanako Noritake, Takeshi Funakoshi, Koichi Uemura.. Modes of Chemically Induced Cell Death. Comprehensive Toxicology 3rd ed Volume 1 (General subjects). 2017.12;

  28. Toshihiko Aki, Kana Unuma, and Koichi Uemura. Emerging roles of mitochondria and autophagy in liver injury during sepsis. Cell Stress. 2017.11; 1 (2): 79-89.

  29. Kanako Noritake, Toshihiko Aki, Moe Kimura, Takeshi Funakoshi, Kana Unuma, Koichi Uemura. Restoration of YAP activation rescues HL-1 cardiomyocytes from apoptotic death by ethanol. J Toxicol Sci. 2017.10; 42 (5): 545-551. ( PubMed, DOI )

  30. Ryo Watanabe, Kana Unuma, Kanako Noritake, Takeshi Funakoshi, Toshihiko Aki, Koichi Uemura.. Ataxia telangiectasia and rad3 related (ATR)-promyelocytic leukemia protein (PML) pathway of the DNA damage response in the brain of rats administered arsenic trioxide. J. Toxicologic Pathology. 2017.07; 30 333-337.

  31. Kana Unuma, Toshihiko Aki, Kanako Noritake, Takeshi Funakoshi, Koichi Uemura. A CO-releasing molecule prevents annexin A2 down-regulation and associated disorders in LPS-administered rat lung. Biochem. Biophys. Res. Commun.. 2017.06; 487 (3): 748-754. ( PubMed, DOI )

  32. Takeshi Funakoshi, Toshihiko Aki, Masateru Tajiri, Kana Unuma, Koichi Uemura. Necroptosis-like Neuronal Cell Death Caused by Cellular Cholesterol Accumulation. J. Biol. Chem.. 2016.11; 291 (48): 25050-25065. ( PubMed, DOI )

  33. Watanabe M, Unuma K, Makino Y, Komatsu A, Yamada A, Nagai H, Uemura K. An Autopsy Case of Asphyxia Caused by Uncontrolled Hemorrhage Following Transbronchial Lung Biopsy J Clin Respir Dis Care. 2016.06; ( DOI )

  34. Haruka Kimura-Kojima, Kana Unuma, Takeshi Funakoshi, Chizuru Kato, Ayumi Komatsu, Toshihiko Aki, Koichi Uemura. Increased MFG-E8 expression and its implications in the vascular pathophysiology of cocaine abuse. J Toxicol Pathol. 2016.04; 29 (2): 131-138. ( PubMed, DOI )

  35. Hajime Utsuno, Toru Kageyama, Keiichi Uchida, Kazuhiko Kibayashi, Koichi Sakurada, Koichi Uemura. Pilot study to establish a nasal tip prediction method from unknown human skeletal remains for facial reconstruction and skull photo superimposition as applied to a Japanese male populations. J Forensic Leg Med. 2016.02; 38 75-80. ( PubMed, DOI )

  36. Yusuke Fujii, Takeshi Funakoshi, Kana Unuma, Kanako Noritake, Toshihiko Aki, Koichi Uemura. Hydrogen sulfide donor NaHS induces death of alveolar epithelial L2 cells that is associated with cellular shrinkage, transgelin expression and myosin phosphorylation. J Toxicol Sci. 2016.01; 41 (5): 645-654. ( PubMed, DOI )

  37. Kyoko Uchida, Kana Unuma, Koichi Uemura. A fatality in a child with severe fatty liver due to n-butane and isopentane poisoning resulting from long-term inhalation of an antiperspirant aerosol. Forensic Sci Med Pathol. 2015.12; 11 (4): 631-632. ( PubMed, DOI )

  38. Mayumi Watanabe, Kana Unuma, Yohsuke Makino, Kanako Noritake, Atsushi Yamada, Hirotaro Iwase, Koichi Uemura. An Autopsy Case of Acute Massive Hematochezia Caused by Superior Mesenteric Vein Thrombosis: A First Report in Forensic Medicine. J. Forensic Sci.. 2015.08; ( PubMed, DOI )

  39. Toshihiko Aki, Takeshi Funakoshi, Koichi Uemura. Regulated necrosis and its implications in toxicology. Toxicology. 2015.07; 333 118-126. ( PubMed, DOI )

  40. Mayumi Watanabe, Kana Unuma, Yusuke Fujii, Kanako Noritake, Koichi Uemura. An autopsy case of vagus nerve stimulation following acupuncture. Leg Med (Tokyo). 2015.03; 17 (2): 120-122. ( PubMed, DOI )

  41. Sayuri Okawa, Kana Unuma, Atsushi Yamada, Toshihiko Aki, Koichi Uemura. Lipopolysaccharide induces expression of collagen VI in the rat lung. J Toxicol Pathol. 2015.01; 28 (1): 37-41. ( PubMed, DOI )

  42. Kana Unuma, Toshihiko Aki, Takeshi Funakoshi, Kyoko Hashimoto, Koichi Uemura. Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy. Autophagy. 2015; 11 (9): 1520-1536. ( PubMed, DOI )

  43. Atsushi Yamada, Toshihiko Aki, Kana Unuma, Takeshi Funakoshi, Koichi Uemura. Paraquat induces epithelial-mesenchymal transition-like cellular response resulting in fibrogenesis and the prevention of apoptosis in human pulmonary epithelial cells. PLoS ONE. 2015; 10 (3): e0120192. ( PubMed, DOI )

  44. Hisashi Nagai, Ichiro Kuwahira, Daryl O Schwenke, Hirotsugu Tsuchimochi, Akina Nara, Sayoko Ogura, Takashi Sonobe, Tadakatsu Inagaki, Yutaka Fujii, Rutsuko Yamaguchi, Lisa Wingenfeld, Keiji Umetani, Tatsuo Shimosawa, Ken-Ichi Yoshida, Koichi Uemura, James T Pearson, Mikiyasu Shirai. Pulmonary Macrophages Attenuate Hypoxic Pulmonary Vasoconstriction via β3AR/iNOS Pathway in Rats Exposed to Chronic Intermittent Hypoxia. PLoS ONE. 2015; 10 (7): e0131923. ( PubMed, DOI )

  45. Kanako Noritake, Toshihiko Aki, Takeshi Funakoshi, Kana Unuma, Koichi Uemura. Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes. PLoS ONE. 2015; 10 (8): e0136952. ( PubMed, DOI )

  46. Hisashi Nagai, Ichiro Kuwahira, Daryl O Schwenke, Hirotsugu Tsuchimochi, Akina Nara, Tadakatsu Inagaki, Sayoko Ogura, Yutaka Fujii, Keiji Umetani, Tatsuo Shimosawa, Ken-ichi Yoshida, James T Pearson, Koichi Uemura, Mikiyasu Shirai. β2-Adrenergic receptor-dependent attenuation of hypoxic pulmonary vasoconstriction prevents progression of pulmonary arterial hypertension in intermittent hypoxic rats. PLoS ONE. 2014; 9 (10): e110693. ( PubMed, DOI )

  47. Funakoshi-Hirose I, Aki T, Unuma K, Funakoshi T, Noritake K, Uemura K.. Distinct effects of methamphetamine on autophagy-lysosome and ubiquitin-proteasome systems in HL-1 cultured mouse atrial cardiomyocytes. Toxicology. 2013; 312 (4): 74-82. ( DOI )

  48. Fujii Y, Funakoshi T, Uchida K, Watanabe M, Saka K, Uemura K.. An autopsy case of acute carbon monoxide poisoning with fatal hypnotic drugs in the blood. Int Med J. 2013;

  49. Unuma K, Aki T, Matsuda S, Funakoshi T, Yoshida K, Uemura K.. Inducer of heme oxygenase-1 cobalt protoporphyrin accelerates autophagy and suppresses oxidative damages during lipopolysaccharide treatment in rat liver. Hepatol Res.. 2013; 43 (1): 91-96. ( DOI )

  50. Unuma K, Aki T, Funakoshi T, Yoshida K, Uemura K.. Cobalt Protoporphyrin Accelerates TFEB Activation and Lysosome Reformation during LPS-Induced Septic Insults in the Rat Heart. PLoS One.. 2013; 8 (2): e56526. ( DOI )

  51. Bessho M, Aki T, Funakoshi T, Unuma K, Noritake K, Kato C, Uemura K.. Rho-Kinase Inhibitor Y-27632 Attenuates Arsenic Trioxide Toxicity in H9c2 Cardiomyoblastoma Cells. Cardiovasc Toxicol.. 2013; ( DOI )

  52. Aki T, Funakoshi T, Unuma K, Uemura K.. Impairment of autophagy: From hereditary disorder to drug intoxication. Toxicology. 2013; 311 (3): 2025-212. ( DOI )

  53. Unuma K, Harada K, Oka T, Uemura K.. Starch accumulation in the lungs of two infants following positive ventilation. Forensic Sci Med Pathol. 2013; ( DOI )

  54. Funakoshi T, Aki T, Unuma K, Uemura K.. Lysosome vacuolation disrupts the completion of autophagy during norephedrine exposure in SH-SY5Y human neuroblastoma cells. Brain Res.. 2013; 1490 9-22. ( DOI )

  55. Unuma K, Aki T, Matsuda S, Funakoshi T, Yoshida K, Uemura K.. Elimination and active extrusion of liver mitochondrial proteins during LPS administration in rat. Hepatology Res. 2013; 43 (5): 526-534. ( DOI )

  56. Nara A, Aki T, Funakoshi T, Unuma K, Uemura K.. Hyperstimulation of macropinocytosis leads to lysosomal dysfunction and cell death during exposure to methamphetamine in differentiated SH-SY5Y cells. Brain Res. 2012; 1466 1-14.

  57. Aki T, Nara A, Uemura K.. Cytoplasmic vacuolization during exposure to drugs and other substances. Cell Biol Toxicol. 2012; 28 (3): 12-131.

  58. Noritake K, Aki T, Funakoshi T, Unuma K, Nara A, Kato C, Uemura K.. Critical roles of Rho-associated kinase in membrane blebbing and mitochondrial pathway of apoptosis caused by 1-butanol. Toxicol in vitro. 2012; 26 (6): 849-855.

  59. Bessho M, Unuma K, Nara A, Uemura K.. A case in which a bone fragment caused by a bullet made a second channel in addition to the bullet channel. Leg Med (Tokyo). 2012; 14 (4): 188-190.

  60. Unuma K, Uozaki H, Kuroda R, Uemura K, Yoshida K.. Death from axillary haemorrhage during haemodialysis in a patient with a histoly of microscopic polyangiitis. BMJ Case Rep. 2012; ( DOI )

  61. Funakoshi T, Aki T, Nakayama H, Watanuki Y, Imori S, Uemura K.. Reactive oxygen species-independent rapid initiation of mitochondrial apoptotic pathway by chelerythrine. Toxicol In Vitro. 2011; 25 (8): 1581-1587.

  62. Unuma K, Harada K, Funakoshi T, Uemura K.. Sudden death of an alcoholic elderly man with acute esophageal necrosis (black esophagus). Forensic Sci Int. 2011; 212 (1-3): e15-e17.

  63. Noritake K, Unuma K, Nara A, Uchida K, Shiratori T, Watanuki Y, Funakoshi T, Uemura K. Autopsy findings of a patient with rapidly progressive massive ascites caused by alcoholic cirrhosis. Legal Medicine (Tokyo). 2011; 13 (3): 148-150. ( PubMed, DOI )

  64. Nara A, Aki T, Funakoshi T, Uemura K. Methamphetamine induces macropinocytosis in differentiated SH-SY5Y human neuroblastoma cells. Brain Res. 2010.09; 1352 1-10. ( PubMed, DOI )

  65. Aki T, Nara A, Funakoshi T, Uemura K. Bifurcate effects of glucose on caspase-independent cell death during hypoxia. Biochem Biophys Res Commun. 2010.06; 396 (3): 614-618. ( PubMed, DOI )

  66. Nara A, Aki T, Funakoshi T, Uchida K, Nakayama H, Uemura K. Death due to blood transfusion-induced anaphylactic shock: A case report. Leg Med (Tokyo). 2010.05; 12 (3): 148-150. ( PubMed, DOI )

  67. Mihoko Kondo-Nakamura, Kaori Shintani-Ishida, Koichi Uemura, Ken-ichi Yoshida.. Brief exposure to carbon monoxide preconditions cardiomyogenic cells against apoptosis in ischemia reperfusion. Biochem Biophys Res Commun. 2010; 393 449-454.

  68. Koichi Uemura , Kyoko Uchida, Akina Nara and Eriko Ochiai.. A fatal case of air-bag-mediated liver injury in an unrestrained driver. Legal Med. 2009; 11 S555-S557.

  69. Uemura K, Shintani-Ishida K, Saka K, Nakajima M, Ikegaya H, Kikuchi Y, Yoshida K. Biochemical blood markers and sampling sites in forensic autopsy. J Forensic Legal Med. 2008; 15 312-317.

  70. Uemura K, Takahashi S, Shintani-Ishida K, Nakajima M, Saka K, Yoshida K. A death due to perirenal hematoma complicating extracorporeal shockwave lithotripsy. Forensic Sci. 2008; 53 469-471.

  71. Uemura K, Ueyama T, Shintani-Ishida K, Unuma K, Yoshida K. An autopsy report on four sudden cardiac death cases by immobilization. Int Med J. 2008; 15 301-305.

  72. Ohno H, Uemura K, Shintani-Ishida K, Nakamura M, Inomata M, Yoshida K.. Ischemia promotes calpain-mediated degradation of p120-catenin in SH-SY5Y cells. Biochem Biophy Res Comm. 2007; 353 (3): 547-552.

  73. Saka K, Uemura K, Shintani-Ishida K, Yoshida K. Acetic acid improves the sensitivity of theophylline analysis by gas chromatography?mass spectrometry. J Chromato B. 2007; 846 (1-2): 240-244.

  74. Uemura K, Kikuchi Y, Shintani-Ishida K, Nakajima M, Yoshida K. A fatal case of post-operative pulmonary thromboembolism with cosmetic liposuction. J Clin Forensic Med. 2006; 13 (1): 41-43.

  75. Uemura K, Fujimiya T, Ohbora Y, Yasuhara M and Yoshida K. Individual Differences in the Kinetics of Alcohol Absorption and Elimination: A Human Study. Forensic Sci Med Pathol. 2005; 1 27-30.

  76. Uemura K, Adachi-Akahane S, Shintani-Ishida K, Yoshida K. Carbon monoxide protects cardiomyogenic cells against ischemic death through L-type Ca2+ channel inhibition. Biochem Biophys Res Commun. 2005; 334 (2): 661-668.

  77. Ohnishi ST, Ohnishi T, Muranaka S, Fujita H, Kimura H, Uemura K, Yoshida K, Utsumi K.. A possible site of superoxide generation in the complex I segment of rat heart mitochondria. J Bioenerg Biomembr. 2005; 37 (1): 1-15.

  78. Uemura K, Yoshida K, et al.. Sudden death of a patient with primary hypereosinophilia, colon tumours, and pulmonary emboli. J Clin Pathol. 2004; 57 (5): 541-543.

  79. Uemura K, Aki T, Yamaguchi K, Yoshida K. Protein kinase C-e protects PC12 cells against methamphetamine-induced death : Possible involvement of suppression of glutamate receptor. Life Sci. 2003; 72 1595-1607.

  80. Uemura K, Hoshino S, Uchida K, Tsuruta R, Maekawa T, Yoshida K. Hypothermia attenuates delayed cortical cell death and ROS generation following CO inhalation. Toxicol Lett. 2003; 145 (2): 101-106.

  81. Uemura K, Sorimachi Y, Yashiki M, Yoshida K. Two fatal cases involving concurrent use of methamphetamine and morphine. J Forensic Sci. 2003; 48 (5): 1179-1181.

  82. Uemura K, Harada K, Sadamitsu D, Tsuruta R, Takahashi M, Aki T, Yasuhara M, Maekawa T, Yoshida K.. Apoptotic and necrotic brain lesions in a fatal case of carbon monoxide poisoning. Forensic Sci Int. 2001; 116 (2-3): 213-219.

  83. Uemura K, Yoshida K. Seat belt induced transection of trachea in a child held on laps of adult upon car diving. J Forensic Sci. 2001; 46 (3): 714-716.

  84. Kudo R, Adachi J, Uemura K, Maekawa T, Ueno Y, Yoshida K. Lipid peroxidation in the rat brain after CO inhalation is temperature dependent. Free Radical Biol Med. 2001; 31 (11): 1417-1423.

  85. Uemura K, Harada K, Shiotani A, Kai A, Urata Y, Yasuhara M, Yoshida K. Obesity-sleep apnea (Pickwickian) syndrome: autopsy findings and a medicolegal review. Legal Med. 2000; 2 36-41.

  86. Uemura K, Li Y-J, Ohbora Y, Fujimiya T, Komura S.. Effects of repeated cocaine administration on alcohol consumption. J Stud Alc. 1998; 59 (1): 115-118.

  87. Uemura K, Komura S. Death caused by triazolam and ethanol intoxication. Am J Foren Med Path. 1995; 16 (1): 66-68.

  88. Imagawa T, Uemura K, Nagai Z, Kawanisi M. Synthesis of 2-(1-hydroxyalkyl) acryronitriles by the cocatalysis of a base and an acid. Synth Commun. 1984; 14 (13): 1267-1273.

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Books etc 【 display / non-display

  1. Toshihiko Aki, Kanako Noritake, Kana Unuma, and Koichi Uemura. “Autophagy in health and disease”, “Stem Cell Biology and Regenerative Medicine” book series. Humana press, Springer-Nature, 2018 Autophagic regulation of cardiomyocyte survival and heart regeneration. (ISBN : 978-3-319-98145-1)

  2. Toshihiko Aki, Kanako Noritake, Takeshi Funakoshi, Koichi Uemura.. Comprehensive Toxicology 3rd ed Volume 1. Elsevier UK, 2018 Modes of Chemically Induced Cell Death. (ISBN : 9780081006016)

Conference Activities & Talks 【 display / non-display

  1. 船越丈司、古川真子、秋利彦、上村公一. コカイン長期曝露による神経細胞ミトコンドリアダイナミクスへの影響. 第42回日本分子生物学会年会 2019.12 福岡

  2. 渡邊 嶺、鵜沼 香奈、秋 利彦、上村 公一. . ラット脳組織における三酸化二ヒ素のPML及びDNA損傷チェックポイント機構への影響.. 第91回日本生化学会大会 2018.09 京都

  3. Rina Kaseda, Toshihiko Aki, Koichi Uemura. SH-SY5Y human neuroblastoma cell death by methamphetamine involves downregulation of cell cycle regulators. IALM 2018 2018.06.08

  4. Kana Unuma, Toshihiko Aki, Ryo Watanabe, Koichi Uemura. Down-regulation of cardiac contractile protein is involved in cardiac dysfunction during sepsis and is mitigated by carbon monoxide. IALM 2018 2018.06.08

  5. Minegishi S, Ishii N, Utuno H, Noritake K, Funakoshi T, Uemura K, Sakuma A, Saitoh H, Ohtani S, Sakurada K.. Preparation of dentin standard samples for age estimation based on increased aspartic acid racemization rate with overheating.. 第102次日本法医学術全国集会 2018.06.07 福岡

  6. Hajime Utsuno, Toru Kageyama, Keiichi Uchida, Namiko Ishii, Saki Minegishi, Koichi Sakurada, Koichi Uemura. Morphological sex differences of mid facial proportion in Japanese population. IALM 2018 2018.06.06 Fukuoka, Japan

  7. Naho Hirayama, Toshihiko Aki, Koichi Uemura. Paraquat-induced cell death pathway, mmitochondrial stress and autophagy in human neuronal cell line SH-SY5Y.. IALM 2018 2018.06.06

  8. Ryo Watanabe, Midori Nagai, Tomomi Sano, Renho Takahashi, Mako Furukawa, Koichi Uemura. A Case Report of Death from invasive Myocoses. IALM 2018 2018.06.06

  9. Funakoshi-Hirose I, Funakoshi T, Kojima H, Saka K, Uemura K. Sudden death after inhalation of synthetic cannabinoids. 9th International Symposium on Advances in Legal Medicine 2014.06

  10. Yamada A, Funakoshi T, Komatsu A, Aihara Y, Uchida K, Uemura K. An autopsy case of severe hyponatremia suspected to be caused by polydipsia.. 9th International Symposium on Advances in Legal Medicine 2014.06

  11. Watanabe M, Unuma K, Fujii Y, Noritake K, Uemura K. A fatal case of vagus nerve injury after acupuncture. 9th International Symposium on Advances in Legal Medicine 2014.06

  12. Noritake K, Aki T, Uemura K. Ethanol induces apoptosis with alterations of Cx43 expression and distribution in HL-1 cells.. 9th International Symposium on Advances in Legal Medicine 2014.06

  13. Fujimiya T, Hakucho A, Takase I, Liu X, Uemura K, Liu J. Pharmacokinetic study of alcohol first-pass metabolism in human low-dose cases. 9th International Symposium on Advances in Legal Medicine 2014.06

  14. Yamada A, Aki T, Uemura K. Differential induction of epithelial-mesenchymal transition and cell death during paraquat poisoning in human alveolar cell line A549.. 9th International Symposium on Advances in Legal Medicine 2014.06

  15. Kana Unuma, Toshihiko Aki, Takeshi Funakoshi, Koichi Uemura. Secretion of mitochondrial contents through autophagolysosomal exocytosis from lipopolysaccharide-stimulated hepatocytes and embryonic fibroblasts.. 9th International Symposium on Advances in Legal Medicine 2014.06 Fukuoka,Japan

  16. Watanabe M, Funakoshi T, Unuma K, Aki T, Uemura K. Activation of ubiquitin-proteasome system plays a protective role in arsenic trioxide-induced cardiotoxicity. 9th International Symposium on Advances in Legal Medicine

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Performance of duties 【 display / non-display

  • ,2017.01 - 2017.12