Personnel Information

写真a

TSUCHIYA Kiichirou


Job title

Associate Professor

Laboratory Address

1-5-45 Yushima, Bunkyo-ku, Tokyo

Research Areas, Keywords

intestinal differentiation, IBD, cancer stem

Degree 【 display / non-display

  • doctor, Tokyo Medical and Dental University

Campus Career 【 display / non-display

  • 1998.04
    -
    2005.03
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Internal Medicine, Gastroenterology and Hepatology, Senior Resident
  • 2005.04
    -
    2007.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Systemic Organ Regulation, Gastroenterology and Hepatology, Assistant Professor
  • 2007.04
    -
    2012.03
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Internal Medicine, Gastroenterology and Hepatology, Junior Associate Professor
  • 2012.04
    -
    2013.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Endowed Departments, Department of Advanced Therapeutics for GI Diseases, Junior Associate Professor
  • 2013.04
    -
    2015.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Endowed Departments, Department of Advanced Therapeutics for GI Diseases, Associate Professor

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External Career 【 display / non-display

  • 1999.07
    -
    2001.03
    , Graduate Student
  • 1996.10
    -
    1998.06
    , Trainee Resident

Academic Society Affiliations 【 display / non-display

  • American Gastroenterological Association

Academic Activity 【 display / non-display

  • Fellow
  • editor
  • Journal of Gastroenterology editor

Research Areas 【 display / non-display

  • Gastroenterology

Qualification Acquired 【 display / non-display

  • Doctor

 

Published Papers & Misc 【 display / non-display

  • Yuria Takei, Yasuhiro Nemoto, Ryo Morikawa, Shohei Tanaka, Shigeru Oshima, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe. T cells show amoeboid shape and frequent morphological change in vitro, and localize to small intestinal intraepithelial region in vivo. Biochem. Biophys. Res. Commun.. 2020.03; 523 (2): 328-335. ( PubMed, DOI )

  • Shohei Tanaka, Yasuhiro Nemoto, Yuria Takei, Ryo Morikawa, Shigeru Oshima, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Susanne Stutte, Mamoru Watanabe. High-fat diet-derived free fatty acids impair the intestinal immune system and increase sensitivity to intestinal epithelial damage. Biochem. Biophys. Res. Commun.. 2020.02; 522 (4): 971-977. ( PubMed, DOI )

  • Maiko Motobayashi, Katsuyoshi Matsuoka, Kento Takenaka, Toshimitsu Fujii, Masakazu Nagahori, Kazuo Ohtsuka, Fumihiko Iwamoto, Kiichiro Tsuchiya, Mariko Negi, Yoshinobu Eishi, Mamoru Watanabe. Predictors of mucosal healing during induction therapy in patients with acute moderate-to-severe ulcerative colitis. J. Gastroenterol. Hepatol.. 2019.06; 34 (6): 1004-1010. ( PubMed, DOI )

  • Sho Watanabe, Kiichiro Tsuchiya, Ryu Nishimura, Tomoaki Shirasaki, Nobuhiro Katsukura, Shuji Hibiya, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe. Mutation by CRISPR System Enhances the Malignant Potential of Colon Cancer. Mol. Cancer Res.. 2019.04; 17 (7): 1459-1467. ( PubMed, DOI )

  • Ami Kawamoto, Sayaka Nagata, Sho Anzai, Junichi Takahashi, Mao Kawai, Minami Hama, Daichi Nogawa, Kouhei Yamamoto, Reiko Kuno, Kohei Suzuki, Hiromichi Shimizu, Yui Hiraguri, Shiro Yui, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Ohtsuka, Masanobu Kitagawa, Ryuichi Okamoto, Mamoru Watanabe. Ubiquitin D is Upregulated by Synergy of Notch Signalling and TNF-α in the Inflamed Intestinal Epithelia of IBD Patients. J Crohns Colitis. 2019.03; 13 (4): 495-509. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Sakurako Kobayashi, Satoshi Watanabe, Yosuke Yoneyama, Kousuke Tanimoto, Ryu Nishimura, Sayaka Nagata, Masami Inoue, Kouhei Suzuki, Sei Kakinuma, Kiichiro Tsuchiya, Ryuichi Okamoto, Mamoru Watanabe, Takanori Takebe, Shiro Yui. Conceptual basis of lineage shift between intestinal epithelium and hepatocytes. Keystone Symposia, Tissue Organoids as Models of Host Physiology and Pathophysiology of Disease 2020.01.22 Vancouver(Canada)

  • Shuji Hibiya, Kiichiro Tsuchiya, Ryu Nishimura, Sho Watanabe, Nobuhiro Katsukura, Tomoaki Shirasaki, Ryuichi Okamoto, Mamoru Watanabe. Establishment of chronic inflammation model using human small intestinal and colonic organoids. UEG Week 2019 2019.10.23 Fira Gran Via, Barcelona, Spain

  • Shuji Hibiya, Kiichiro Tsuchiya, Ryu Nishimura, Tomoaki Shirasaki, Sho Watanabe, Nobuhiro Katsukura, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe. Long-term inflammation model using human colonic organoids. The 7th annual meeting of AOCC 2019.06.15 Taipei, Taiwan

  • Kiichiro Tsuchiya. Organoid model for the carcinogenesis process of CAC. IMKASID 2019 2019.04.12 Seoul(Korea)

  • Tsuchiya K, Watanabe S, Shirasaki T, Nishimura R, Katsukura N, Hibiya S, Okamoto R, Nakamura T, Watanabe M. TP53 mutation in human colonic organoids acquires resistance to in vitro long-term inflammation.. ECCO2019 2019.03.09 Copenhagen(Denmark)

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