Personnel Information

写真a

MIKI Yoshio


Job title

Professor

Laboratory Address

1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, JAPAN

Mail Address

The inquiry by e-mail is 《here

Homepage URL

http://www.tmd.ac.jp/mri/mgen/index_j.html

Research Areas, Keywords

Carcinogenesis, Breast Cancer, Genome Medicine, Hereditary Cancer, Genome Stability Research

Graduating School 【 display / non-display

  • Wakayama Medical University, Faculty of Medicine, 1981.03, Graduated

Graduate School 【 display / non-display

  • Hyogo College of Medicine, Graduate School, Division of Medicine, Doctor's Course, Completed

Campus Career 【 display / non-display

  • 2002.04
    -
    Now
    Tokyo Medical and Dental University, Medical Research Institute, Medical Genomics, Molecular Genetics, Professor
  • 2002.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Applied Gene Medicine, Professor

External Career 【 display / non-display

  • , Trainee Resident

Academic Society Affiliations 【 display / non-display

  • Japanese Organization of Hereditary Breast and Ovarian Cancer(JOHBOC)

Research Areas 【 display / non-display

  • Tumor biology

  • Pathological medical chemistry

  • Human genetics

  • Medical genome science

Qualification Acquired 【 display / non-display

  • Doctor

 

Research Theme 【 display / non-display

  • Molecular Mechanisms of Breast Cancer Progression

  • Cancer Genome Research

  • Cell Death Signaling in Cancer

  • DNA Damage Repair and Genome Instability in Cancer

  • Hormone-Dependent Breast Cancer Cell Growth

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Published Papers & Misc 【 display / non-display

  • Inazawa J, Miki Y, Nakamura Y. Integrative cancer genomics in the era of precision cancer medicine. Journal of human genetics. 2021.09; 66 (9): 843. ( PubMed, DOI )

  • Sunada S, Saito H, Zhang D, Xu Z, Miki Y. CDK1 inhibitor controls G2/M phase transition and reverses DNA damage sensitivity. Biochemical and biophysical research communications. 2021.04; 550 56-61. ( PubMed, DOI )

  • Deng Yu, Otsuka Nao, Nakanishi Akira, Miki Yoshio. The role of BRCA2 in H3K4 methylation mediated by MLL CANCER SCIENCE. 2021.02; 112 676.

  • Tojo Yo, Nakanishi Akira, Miki Yoshio. The physiological role of centrosome pairs during S phase CANCER SCIENCE. 2021.02; 112 306.

  • Miki Yoshio, Sunada Shigeaki, Nakanishi Akira. Targeting DNA repair pathways for new cancer treatment CANCER SCIENCE. 2021.02; 112 157.

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Conference Activities & Talks 【 display / non-display

  • Yoshida Reiko, Hagio Taichi, Kaneyasu Tomoko, Gotoh Osamu, Osako Tomo, Tanaka Norio, Amino Sayuri, Yaguchi Noriko, Nakashima Eri, Kitagawa Dai, Ueno Takayuki, Ohno Shinji, Nakajima Takeshi, Nakamura Seigo, Miki Yoshio, Hirota Toru, Takahashi Shunji, Matsuura Masaaki, Noda Tetsuo, Mori Seiichi. Pathogenicity assessment of variants for breast cancer susceptibility genes based on BRCAness of tumor sample(和訳中). Cancer Science 2021.03.01

  • Chin Yoon Ming, Takahashi Yoko, Chan Hiu Ting, Otaki Masumi, Fujishima Makoto, Shibayama Tomoko, Miki Yoshio, Ueno Takayuki, Nakamura Yusuke, Low Siew-Kee. 早期および進行乳癌の血漿中の循環腫瘍DNAのウルトラディープ標的シーケンシング(Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer). Cancer Science 2021.01.01

  • 三木 義男, 砂田 成章, 中西 啓. 遺伝子異常を標的とした乳癌の治療戦略 BRCA1/2変異 基礎から臨床へ. 日本癌治療学会学術集会抄録集 2020.10.01

  • 郭 倩倩, 徐 澤宇, 斉藤 広子, 砂田 成章, 三木 義男. 臨床的意義不明なBRCA2バリアントの相同組換え活性. 日本癌学会総会記事 2020.10.01

  • Enkhbat Gerelmaa, Uetake Hiroyuke, 中西 啓, 三木 義男. 細胞周期におけるBRCA2タンパク質レベルの制御メカニズムの解明(Elucidation of the regulation mechanism of BRCA2 protein level in cell cycle). 日本癌学会総会記事 2020.10.01

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