Personnel Information

写真a

YOKOYAMA Miki


Job title

Associate Professor

Laboratory Phone number

+81-3-5803-5567

Mail Address

m.yokoyama.bch@tmd.ac.jp

Research Areas, Keywords

Lysosomes, Lipids, Membrane protein assembly, CD38
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Graduating School 【 display / non-display 】

  • The University of Tokyo, Faculty of Science, Biochemistry and biophysiology, 1986, Graduated

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Graduate School 【 display / non-display 】

  • The University of Tokyo, Graduate School, Division of Science, Biochemistry and biophysiology, Doctor's Course, 1986, Completed

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Degree 【 display / non-display 】

  • PhD, The University of Tokyo

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Campus Career 【 display / non-display 】

  • 1900.01
    -
    2018.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Biochemistry， Associate Professor
  • 2004.02
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Biochemistry， Associate Professor
  • 2004.02
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Biochemistry， Associate Professor
  • 2018.04
    -
    2021.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Biochemistry， Associate Professor
  • 2021.04
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Bio-Matrix， Department of Biochemistry， Associate Professor
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Research Areas 【 display / non-display 】

  • Oral biological science

  • Structural biochemistry

  • Functional biochemistry

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Research Theme 【 display / non-display 】

  • Cell-surface assembly of proteins, 2010

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Published Papers & Misc 【 display / non-display 】

  1. Kazue Terasawa, Yuji Kato, Yuta Ikami, Kensaku Sakamoto, Kazumasa Ohtake, Seisuke Kusano, Yuri Tomabechi, Mutsuko Kukimoto-Niino, Mikako Shirouzu, Jun-Lin Guan, Toshihide Kobayashi, Takanori Iwata, Tetsuro Watabe, Shigeyuki Yokoyama, Miki Hara-Yokoyama. Direct homophilic interaction of LAMP2A with the two-domain architecture revealed by site-directed photo-crosslinks and steric hindrances in mammalian cells. Autophagy. 2021.04; 1-19. ( PubMed, DOI )

  2. Kazue Terasawa, Tatsuro Seike, Kensaku Sakamoto, Kazumasa Ohtake, Tohru Terada, Takanori Iwata, Tetsuro Watabe, Shigeyuki Yokoyama, Miki Hara-Yokoyama. Site-specific photo-crosslinking/cleavage for protein-protein interface identification reveals oligomeric assembly of lysosomal-associated membrane protein type 2A in mammalian cells. Protein Sci. 2023.12; 32 (12): e4823. ( PubMed, DOI )

  3. Yuta Ikami, Kazue Terasawa, Tetsuro Watabe, Shigeyuki Yokoyama, Miki Hara-Yokoyama. The two-domain architecture of LAMP2A within the lysosomal lumen regulates its interaction with HSPA8/Hsc70 Autophagy Reports. 2022.05; 1 (1): 205-209. ( DOI )

  4. Yuta Ikami, Kazue Terasawa, Kensaku Sakamoto, Kazumasa Ohtake, Hiroyuki Harada, Tetsuro Watabe, Shigeyuki Yokoyama, Miki Hara-Yokoyama. The two-domain architecture of LAMP2A regulates its interaction with Hsc70. Exp Cell Res. 2022.02; 411 (1): 112986. ( PubMed, DOI )

  5. Daisuke Yamamoto, Kou Kayamori, Kei Sakamoto, Maiko Tsuchiya, Tohru Ikeda, Hiroyuki Harada, Tetsuya Yoda, Tetsuro Watabe, Miki Hara-Yokoyama. Intracellular claudin-1 at the invasive front of tongue squamous cell carcinoma is associated with lymph node metastasis. Cancer Sci.. 2020.02; 111 (2): 700-712. ( PubMed, DOI )

  6. Yuji Kato, Satoko Arakawa, Kazue Terasawa, Jin-Ichi Inokuchi, Takanori Iwata, Shigeomi Shimizu, Tetsuro Watabe, Miki Hara-Yokoyama. The ceramide analogue N-(1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide induces large lipid droplet accumulation and highlights the effect of LAMP-2 deficiency on lipid droplet degradation. Bioorg. Med. Chem. Lett.. 2020; 30 (3): 126891. ( PubMed, DOI )

  7. Hara-Yokoyama M, Kurihara H, Ichinose S, Matsuda H, Ichinose S, Kurosawa M, Tada N, Iwahara C, Terasawa K, Podyma-Inoue KA, Furukawa K, Iwabuchi K. KIF11 as a Potential Marker of Spermatogenesis Within Mouse Seminiferous Tubule Cross-sections. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2019.08; 22155419871027. ( PubMed, DOI )

  8. Jin-Ichi Inokuchi, Takashi Ode, Miki Hara-Yokoyama. Pharmacological Modulation of Glycosphingolipid Metabolism. Methods Mol. Biol.. 2018; 1804 401-410. ( PubMed, DOI )

  9. 井上 カタジナ・アンナ, 高橋 和樹, 松田 匠源, 吉松 康裕, 横山 三紀, 渡部 徹郎. TGF-β誘発性上皮間葉転換中の口腔扁平上皮癌細胞が分泌するエキソソーム(Exosomes secreted by oral squamous carcinoma cells undergoing TGF-β-induced epithelial to mesenchymal transition) 生命科学系学会合同年次大会. 2017.12; 2017年度 [1P-0028]. ( ichushi )

  10. Doino M, Yokoyama M, Sasaki Y, Kondo K, Yasuda Y, and Arakawa S.. Evaluation of the relationship between salivary concentration of anti–heat shock protein immunoglobulin and clinical manifestations of Behçet's disease Scandinavian Journal of Rheumatology. 2017.09; 46 (5): 381-387.

  11. Takashi Ode, Katarzyna A Podyma-Inoue, Kazue Terasawa, Jin-Ichi Inokuchi, Toshihide Kobayashi, Tetsuro Watabe, Yuichi Izumi, Miki Hara-Yokoyama. PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum. Exp. Cell Res.. 2017.01; 350 (1): 103-114. ( PubMed, DOI )

  12. Katarzyna A Podyma-Inoue, Takuya Moriwaki, Anupama R Rajapakshe, Kazue Terasawa, Miki Hara-Yokoyama. Characterization of Heparan Sulfate Proteoglycan-positive Recycling Endosomes Isolated from Glioma Cells. Cancer Genomics Proteomics. 2016.12; 13 (6): 443-452. ( PubMed )

  13. Kazue Terasawa, Yuri Tomabechi, Mariko Ikeda, Haruhiko Ehara, Mutsuko Kukimoto-Niino, Motoaki Wakiyama, Katarzyna A Podyma-Inoue, Anupama R Rajapakshe, Tetsuro Watabe, Mikako Shirouzu, Miki Hara-Yokoyama. Lysosome-associated membrane proteins-1 and -2 (LAMP-1 and LAMP-2) assemble via distinct modes. Biochem. Biophys. Res. Commun.. 2016.10; 479 (3): 489-495. ( PubMed, DOI )

  14. Kazue Terasawa, Anupama R Rajapakshe, Katarzyna A Podyma-Inoue, Chiemi Mishima-Tsumagari, Masaki Yanagishita, Miki Hara-Yokoyama. Preferential recognition of isocitrate dehydrogenase by a rabbit monoclonal antibody (ab124797) against the C-terminal peptide of RANKL. J. Immunol. Methods. 2015.05; 420 1-10. ( PubMed, DOI )

  15. Anupama R Rajapakshe, Katarzyna A Podyma-Inoue, Kazue Terasawa, Katsuya Hasegawa, Toshimitsu Namba, Yasuhiro Kumei, Masaki Yanagishita, Miki Hara-Yokoyama. Lysosome-associated membrane proteins (LAMPs) regulate intracellular positioning of mitochondria in MC3T3-E1 cells. Exp. Cell Res.. 2014.09; ( PubMed, DOI )

  16. Hara-Yokoyama Miki. Glycosylation Regulates CD38 Assembly on the Cell Surface Trends in Glycobiology and Glycotechnology. 2013.11; 25 (146): 215-225. ( DOI )

  17. Miki Hara-Yokoyama, Kazue Terasawa, Shizuko Ichinose, Akihiko Watanabe, Katarzyna A Podyma-Inoue, Kazunari Akiyoshi, Yasuyuki Igarashi, Masaki Yanagishita. Sphingosine kinase 2 inhibitor SG-12 induces apoptosis via phosphorylation by sphingosine kinase 2. Bioorganic & Medicinal Chemistry Letters. 2013.04; 23 (7): 2220-2224. ( PubMed, DOI )

  18. Miki Hara-Yokoyama, Mutsuko Kukimoto-Niino, Kazue Terasawa, Satoru Harumiya, Katarzyna A Podyma-Inoue, Nobumasa Hino, Kensaku Sakamoto, Satsuki Itoh, Noritaka Hashii, Yoko Hiruta, Nana Kawasaki, Chiemi Mishima-Tsumagari, Yoko Kaitsu, Tomoko Matsumoto, Motoaki Wakiyama, Mikako Shirouzu, Takeshi Kasama, Hiroshi Takayanagi, Naoko Utsunomiya-Tate, Kiyoshi Takatsu, Toshiaki Katada, Yoshio Hirabayashi, Shigeyuki Yokoyama, Masaki Yanagishita. Tetrameric interaction of the ectoenzyme CD38 on the cell surface enables its catalytic and raft-association activities. Structure. 2012.09; 20 (9): 1585-1595. ( PubMed, DOI )

  19. Seisuke Kusano, Mutsuko Kukimoto-Niino, Nobumasa Hino, Noboru Ohsawa, Masashi Ikutani, Satoshi Takaki, Kensaku Sakamoto, Miki Hara-Yokoyama, Mikako Shirouzu, Kiyoshi Takatsu, Shigeyuki Yokoyama. Structural basis of interleukin-5 dimer recognition by its α receptor. Protein Science. 2012.06; 21 (6): 850-864. ( PubMed, DOI )

  20. Katarzyna A Podyma-Inoue, Miki Hara-Yokoyama, Tamayuki Shinomura, Tomoko Kimura, Masaki Yanagishita. Syndecans reside in sphingomyelin-enriched low-density fractions of the plasma membrane isolated from a parathyroid cell line. PLoS ONE. 2012; 7 (3): e32351. ( PubMed, DOI )

  21. N Ebe, M Hara-Yokoyama, K Iwasaki, S Iseki, S Okuhara, K A Podyma-Inoue, K Terasawa, A Watanabe, T Akizuki, H Watanabe, M Yanagishita, Y Izumi. Pocket epithelium in the pathological setting for HMGB1 release. Journal of Dental Research. 2011.02; 90 (2): 235-240. ( PubMed, DOI )

  22. Kotone Sano, Yasunori Miyamoto, Nana Kawasaki, Noritaka Hashii, Satsuki Itoh, Misaki Murase, Kimie Date, Miki Yokoyama, Chihiro Sato, Ken Kitajima, Haruko Ogawa. Survival signals of hepatic stellate cells in liver regeneration are regulated by glycosylation changes in rat vitronectin, especially decreased sialylation. The Journal of Biological Chemistry. 2010.06; 285 (23): 17301-17309. ( PubMed, DOI )

  23. Masaki Yanagishita, Katarzyna Anna Podyma-Inoue, Miki Yokoyama. Extraction and separation of proteoglycans. Glycoconjugate Journal. 2009.11; 26 (8): 953-959. ( PubMed, DOI )

  24. Miki Hara-Yokoyama, Tomoko Kimura, Hiroaki Kaku, Motoaki Wakiyama, Yoko Kaitsu, Mio Inoue, Seisuke Kusano, Mikako Shirouzu, Shigeyuki Yokoyama, Toshiaki Katada, Yoshio Hirabayashi, Kiyoshi Takatsu, Masaki Yanagishita. Alteration of enzymatic properties of cell-surface antigen CD38 by agonistic anti-CD38 antibodies that prolong B cell survival and induce activation. International Immunopharmacology. 2008.01; 8 (1): 59-70. ( PubMed, DOI )

  25. Miki Hara-Yokoyama, Kazue Terasawa, Akio Kihara, Jin-Wook Kim, Chan-Seo Park, Yoshio Hirabayashi, Yasuyuki Igarashi, Masaki Yanagishita. Sphingosine Kinase 2 Inhibitor Accelerates Fas-Mediated Cell Death Progression in A20/2J Cells. The Open Bioactive Compounds Journal. 2008; 1 22-27.

  26. Osamu Katsumata, Junko Fujita-Yoshigaki, Miki Hara-Yokoyama, Masaki Yanagishita, Shunsuke Furuyama, Hiroshi Sugiya. Syntaxin6 separates from GM1a-rich membrane microdomain during granule maturation. Biochemical and BIophysical Research Communications. 2007.06; 357 (4): 1071-1077. ( PubMed, DOI )

  27. Kaori Ueno-Noto, Miki Hara-Yokoyama, Keiko Takano. Recognition of tandem sialic acid residues by CD38: a theoretical study. Journal of Computational Chemistry. 2006.01; 27 (1): 53-60. ( PubMed, DOI )

  28. Miki Hara-Yokoyama. Gangliosides potentially inhibit extracellular nucleotide metabolism. Current Medicinal Chemistry. 2006; 13 (19): 2233-2239. ( PubMed )

  29. Osamu Katsumata, Tomoko Kimura, Yasuko Nagatsuka, Yoshio Hirabayashi, Hiroshi Sugiya, Shunsuke Furuyama, Masaki Yanagishita, Miki Hara-Yokoyama. Charge-based separation of detergent-resistant membranes of mouse splenic B cells. Biochemical and BIophysical Research Communications. 2004.07; 319 (3): 826-831. ( PubMed, DOI )

  30. Miki Hara-Yokoyama, Hiromi Ito, Kaori Ueno-Noto, Keiko Takano, Hideharu Ishida, Makoto Kiso. Novel sulfated gangliosides, high-affinity ligands for neural siglecs, inhibit NADase activity of leukocyte cell surface antigen CD38. Bioorganic & Medicinal Chemistry Letters. 2003.10; 13 (20): 3441-3445. ( PubMed )

  31. Yasuko Nagatsuka, Miki Hara-Yokoyama, Takeshi Kasama, Masataka Takekoshi, Fumiko Maeda, Seiji Ihara, Shigeyoshi Fujiwara, Eriko Ohshima, Kumiko Ishii, Toshihide Kobayashi, Kazufumi Shimizu, Yoshio Hirabayashi. Carbohydrate-dependent signaling from the phosphatidylglucoside-based microdomain induces granulocytic differentiation of HL60 cells. Proceedings of the National Academy of Sciences of the United States of America. 2003.06; 100 (13): 7454-7459. ( PubMed, DOI )

  32. Yoko Dohke, Junko Fujita-Yoshigaki, Hiroshi Sugiya, Shunsuke Furuyama, Miki Hara-Yokoyama. Involvement of phospholipase D in the cAMP-regulated exocytosis of rat parotid acinar cells. Biochemical and BIophysical Research Communications. 2002.12; 299 (4): 663-668. ( PubMed )

  33. O Katsumata, M Hara-Yokoyama, C Sautès-Fridman, Y Nagatsuka, T Katada, Y Hirabayashi, K Shimizu, J Fujita-Yoshigaki, H Sugiya, S Furuyama. Association of FcgammaRII with low-density detergent-resistant membranes is important for cross-linking-dependent initiation of the tyrosine phosphorylation pathway and superoxide generation. The Journal of Immunology. 2001.11; 167 (10): 5814-5823. ( PubMed )

  34. H Sugiya, Y Mitsui, H Michikawa, J Fujita-Yoshigaki, M Hara-Yokoyama, S Hashimoto, S Furuyama. Ca(2+)-regulated nitric oxide generation in rabbit parotid acinar cells. Cell Calcium. 2001.08; 30 (2): 107-116. ( PubMed, DOI )

  35. M Hara-Yokoyama, Y Nagatsuka, O Katsumata, F Irie, K Kontani, S Hoshino, T Katada, Y Ono, J Fujita-Yoshigaki, H Sugiya, S Furuyama, Y Hirabayashi. Complex gangliosides as cell surface inhibitors for the ecto-NAD+ glycohydrolase of CD38. Biochemistry. 2001.01; 40 (4): 888-895. ( PubMed )

  36. M Kukimoto, O Nureki, M Shirouzu, T Katada, Y Hirabayashi, H Sugiya, S Furuyama, S Yokoyama, M Hara-Yokoyama. Crystallization and preliminary X-ray diffraction analysis of the extracellular domain of the cell surface antigen CD38 complexed with ganglioside. Journal of Biochemistry. 2000.02; 127 (2): 181-184. ( PubMed )

  37. J Fujita-Yoshigaki, Y Dohke, M Hara-Yokoyama, S Furuyama, H Sugiya. Presence of a complex containing vesicle-associated membrane protein 2 in rat parotid acinar cells and its disassembly upon activation of cAMP-dependent protein kinase. The Journal of Biological Chemistry. 1999.08; 274 (33): 23642-23646. ( PubMed )

  38. Y Dohke, M Hara-Yokoyama, J Fujita-Yoshigaki, R A Kahn, Y Kanaho, S Hashimoto, H Sugiya, S Furuyama. Translocation of Arf1 to the secretory granules in rat parotid acinar cells. Archives of Biochemsitry and Biophysics. 1998.09; 357 (1): 147-154. ( PubMed, DOI )

  39. Y Dohke, M Hara-Yokoyama, J Fujita-Yoshigaki, S Furuyama, H Sugiya. ADP-ribosylation factors in rat parotid acinar cells. European Journal of Morphology. 1998.08; 36 Suppl 186-189. ( PubMed )

  40. J Fujita-Yoshigaki, Y Dohke, M Hara-Yokoyama, S Furuyama, H Sugiya. Snare proteins essential for cyclic AMP-regulated exocytosis in salivary glands. European Journal of Morphology. 1998.08; 36 Suppl 46-49. ( PubMed )

  41. Sugiya H, Michikawa H, Mitsui Y, Fujita-Yoshigaki J, Hara-Yokoyama M, Furuyama S. Ca2+-nitric oxide-cGMP signaling in rabbit parotid acinar cells. European Journal of Morphology. 1998.08; 36 Suppl 194-197. ( PubMed )

  42. H Michikawa, Y Mitsui, J Fujita-Yoshigaki, M Hara-Yokoyama, S Furuyama, H Sugiya. cGMP production is coupled to Ca(2+)-dependent nitric oxide generation in rabbit parotid acinar cells. Cell Calcium. 1998.06; 23 (6): 405-412. ( PubMed )

  43. M Hara-Yokoyama, I Kukimoto, H Nishina, K Kontani, Y Hirabayashi, F Irie, H Sugiya, S Furuyama, T Katada. Inhibition of NAD+ glycohydrolase and ADP-ribosyl cyclase activities of leukocyte cell surface antigen CD38 by gangliosides. The Journal of Biological Chemistry. 1996.05; 271 (22): 12951-12955. ( PubMed )

  44. J Fujita-Yoshigaki, Y Dohke, M Hara-Yokoyama, Y Kamata, S Kozaki, S Furuyama, H Sugiya. Vesicle-associated membrane protein 2 is essential for cAMP-regulated exocytosis in rat parotid acinar cells. The inhibition of cAMP-dependent amylase release by botulinum neurotoxin B. The Journal of Biological Chemistry. 1996.05; 271 (22): 13130-13134. ( PubMed )

  45. M Hara-Yokoyama, Y Hirabayashi, F Irie, B Syuto, K Moriishi, H Sugiya, S Furuyama. Identification of gangliosides as inhibitors of ADP-ribosyltransferases of pertussis toxin and exoenzyme C3 from Clostridium botulinum. The Journal of Biological Chemistry. 1995.04; 270 (14): 8115-8121. ( PubMed )

  46. M Hara-Yokoyama, H Sugiya, S Furuyama, J H Wang, N Yokoyama. Dephosphorylation of ribosomal protein S6 phosphorylated via the cAMP-mediated signaling pathway in rat parotid gland: effect of okadaic acid and Zn2+. Biochemistry and molecular biology international. 1994.12; 34 (6): 1177-1187. ( PubMed )

  47. Hara-Yokoyama M, Sugiya H, Furuyama S. Possible involvement of adenylylation in the modification of a 26 kDa protein in rat parotid acinar cells. Int J Biochem. 1994.09; 26 (9): 1103-1109. ( PubMed )

  48. Yokoyama N, Hara-Yokoyama M, Kobayashi T, Tamura S, Furuyama S, Sugiya H. Involvement of type 2C phosphatase in the dephosphorylation of 26 kDa phosphoprotein in rat parotid acinar cells. Biochemical and BIophysical Research Communications. 1994.04; 200 (1): 497-503. ( PubMed )

  49. O Nureki, K Suzuki, M Hara-Yokoyama, T Kohno, H Matsuzawa, T Ohta, T Shimizu, K Morikawa, T Miyazawa, S Yokoyama. Glutamyl-tRNA synthetase from Thermus thermophilus HB8. Molecular cloning of the gltX gene and crystallization of the overproduced protein. European Journal of Biochemistry. 1992.03; 204 (2): 465-472. ( PubMed )

  50. H Sugiya, M Hara-Yokoyama, S Furuyama. Isoproterenol-stimulated labelling of particulate proteins by using [adenylate-32P]NAD+ independent on a cAMP-dependent protein kinase in parotid acinar cells. FEBS Letters. 1992.03; 300 (2): 171-174. ( PubMed )

  51. M Haruki, R Matsumoto, M Hara-Yokoyama, T Miyazawa, S Yokoyama. Conformational changes of aminoacyl-tRNA and uncharged tRNA upon complex formation with polypeptide chain elongation factor Tu. FEBS Letters. 1990.04; 263 (2): 361-364. ( PubMed )

  52. M Hara-Yokoyama, S Furuyama. An endogenous inhibitor of the ADP-ribosylation of GTP-binding proteins by pertussis toxin is present in bovine brain. Biochemical and BIophysical Research Communications. 1989.04; 160 (1): 67-71. ( PubMed )

  53. M Hara-Yokoyama, S Furuyama. Endogenous inhibitor of the ADP-ribosylation of (a) G-protein(s) as catalyzed by pertussis toxin is present in rat liver. FEBS Letters. 1988.07; 234 (1): 27-30. ( PubMed )

  54. Hara-Yokoyama M, Yokoyama S, Miyazawa T. Conformation change of tRNAGlu in the complex with glutamyl-tRNA synthetase is required for the specific binding of L-glutamate. Biochemistry. 1986.11; 25 (22): 7031-7036. ( PubMed )

  55. Choi BS, Redfield AG. NMR study of isoleucine transfer RNA from Thermus thermophilus. Biochemistry. 1986.04; 25 (7): 1529-1534. ( PubMed )

  56. Yokoyama S, Haruki M, Hara-Yokoyama M, Miyazawa T. Circular dichroism analyses of tRNA X protein interactions. Nucleic Acids Symp Ser. 1986; (17): 199-201. ( PubMed )

  57. N Horie, M Hara-Yokoyama, S Yokoyama, K Watanabe, Y Kuchino, S Nishimura, T Miyazawa. Two tRNAIle1 species from an extreme thermophile, Thermus thermophilus HB8: effect of 2-thiolation of ribothymidine on the thermostability of tRNA. Biochemistry. 1985.10; 24 (21): 5711-5715. ( PubMed )

  58. M Hara-Yokoyama, S Yokoyama, T Miyazawa. Purification and characterization of glutamyl-tRNA synthetase from an extreme thermophile, Thermus thermophilus HB8. Journal of Biochemistry. 1984.11; 96 (5): 1599-1607. ( PubMed )

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Conference Activities & Talks 【 display / non-display 】

  1. Katarzyna A. Inoue, Kazuki Takahashi, Takumi Matsuda, Yasuhiro Yoshimatsu, Miki Yokoyama and Tetsuro Watabe. Exosomes secreted by oral squamous carcinoma cells undergoing TGF-β-induced epithelial to mesenchymal transition. ConBio2017 2017.12.06 神戸市

  2. Katarzyna A. Podyma-Inoue, Miki Yokoyama and Tetsuro Watabe. Characterization of extracellular vesicles isolated from osteoblastic cells lines. 第89回日本生化学会大会 2016.09 仙台市

  3. Katarzyna A. Podyma-Inoue, Anupama R. Rajapakshe, Takuya Moriwaki, Tetsuro Watabe and Miki Yokoyama. Heparan sulfate proteoglycan and intracellular transport; clues from proteomic analysis of transport vesicles. 第88回日本生化学会大会 2015.12 神戸

  4. Miki Yokoyama. Glycosylation regulates CD38 assembly on the cell surface. GLYCOBIOLOGY 2015 2015.08.12 Philadelphia

  5. Takashi Ode, Katarzyna A. Podyma-Inoue, Shinichi Arakawa, Miki Yokoyama, Yuichi Izumi. Intracellular cholesterol trafficking is involved in osteoblastic differentiation of MC3T3-E1 cells. The 58th Spring Meeting of the Japanese Society of Periodontology 2015.05 Chiba, Makuhari

  6. Anupama R. Rajapakshe, Katarzyna A. Podyma-Inoue, Takashi Ode, Miki Hara-Yokoyama. Lysosome-associated memebrane proteins (LAMPs) regulate bidirectional transport of lysosomes in MC3T3-E1 cells. The 58th Spring Meeting of the Japanese Society of Periodontology 2015.05 Chiba, Makuhari

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Others 【 display / non-display 】

  • Protein secrets unveiled: Newl molecular insight of protein–protein interactions，2023.12

  • Lighting the LAMP to reveal mystery of lysosomes，2021.06

  • It's What's Inside That Matters: Locking Up Proteins Enables Cancer Metastasis，2020.02

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