Personnel Information

写真a

ARAKAWA Shinichi


Job title

Professor

Laboratory Address

Section of Periodontology, Dental Hospital, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, Japan 1138549

Mail Address

The inquiry by e-mail is 《here》

Research Areas, Keywords

Functional water, Ozone Ultrafinebubble water, Acidic electrolyzed water, micro-bicidal activity, oral mucositis
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Graduating School 【 display / non-display 】

  • Tokyo Medical and Dental University, Faculty of Dentistry, Graduated

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Graduate School 【 display / non-display 】

  • Tokyo Medical and Dental University, Doctor's Course, 1990.03, Completed

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Campus Career 【 display / non-display 】

  • 1900.01
    -
    2012.06
    Tokyo Medical and Dental University， (Old Organization)Dental Hospital， Hospital Departments， Clinics for Conservation of Oral and Maxillofacial Function， Periodontics， Assistant Professor
  • 2012.07
    -
    2016.02
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Science and Technology， Lifetime Oral Health Care Science， Professor
  • 1994.07
    -
    2018.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Science and Technology， Lifetime Oral Health Care Science， Professor
  • 2016.04
    -
    Now
    Tokyo Medical and Dental University， Faculty of Dentistry， School of Oral Health Care Sciences， Director
  • 2018.04
    -
    2020.06
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Science and Technology， Lifetime Oral Health Care Science， Professor
  • 2020.07
    -
    2023.08
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Science and Technology， Lifetime Oral Health Care Science， Professor
  • 2023.09
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Biomedical Sciences and Engineering， -， -， Professor

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Research Areas 【 display / non-display 】

  • Conservative dentistry

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Qualification Acquired 【 display / non-display 】

  • Dentist

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Published Papers & Misc 【 display / non-display 】

  1. Takeuchi Y, Nemoto T, Kitanaka Y, Aoki A, Izumi Y, Iwata T, Arakawa S. Antibacterial activity of lysozyme-chitosan oligosaccharide conjugates on two periodontal bacteria. Oral diseases. 2023.08; ( PubMed, DOI )

  2. 荒川真一. 超高齢社会だからこそ歯科衛生士が知っておきたい 含嗽剤としての新規機能水 日本歯周病学会会誌. 2023.04; 65 (1): 26-34. ( DOI )

  3. Masayuki Tooi, Yuhei Matsuda, Hui Zhong and Shinichi Arakawa. Association between Clinical Periodontal Features and Glycated Hemoglobin in Patients with Diabetes and Controlled Periodontitis: A Cross-Sectional Study Healthcare. 2023.04; 11 (7): 1-8. ( PubMed, DOI )

  4. Risako Mikami, Koji Mizutani, Shinichi Arakawa, Yuichi Izumi, Takanori Iwata, Jun Asida. Income-related inequalities in the association of smoking with periodontitis: a cross-sectional analysis in Tokyo Metropolitan Districts Clinical Oral Investigation. 2023.02; 27 (2): 519-528.

  5. Mikami Risako, Sudo Takeaki, Fukuba Shunsuke, Takeda Kohei, Matsuura Takanori, Kariya Tomoaki, Takeuchi Shunsuke, Ochiai Akane, Kawamoto Sakurako, Toyoshima Keita, Mizutani Koji, Arakawa Shinichi, Aoki Akira, Iwata Takanori. Prognostic factors affecting periodontal regenerative therapy using recombinant human fibroblast growth factor-2: A 3-year cohort study(タイトル和訳中) Regenerative Therapy. 2022.12; 21 271-276. ( ichushi )

  6. Yuhei Matsuda, Ruriko Mizuno, Saki Miyajima, Shinichi Arakawa and Yuji Kabasawa. A Case of Oral Health Management for a Patient with Extensive Ulceration of the Oral Mucosa Due to Herpes Zoster Healthcare. 2022.11; 10 (11): ( PubMed, DOI )

  7. Risako Mikami, Takeaki Sudo, Shunsuke Fukuba, Kohei Takeda, Takanori Matsuura, Tomoaki Kariya, Shunsuke Takeuchi, Akane Ochiai, Sakurako Kawamoto, Keita Toyoshima, Koji Mizutani, Shinichi Arakawa, Akira Aoki, Takanori Iwata. Prognostic factors affecting periodontal regenerative therapy using recombinant human fibroblast growth factor-2: A 3-year cohort study Regenerative Therapy. 2022.08;

  8. Yuhei Matsuda, Ruwan D. Jayasinghe, Hui Zhong, Shinichi Arakawa and Takahiro Kanno. Oral Health Management and Rehabilitation for Patients with Oral Cancer: A Narrative Review Healthcare. 2022.05; 10 (5): 1-19. ( PubMed, DOI )

  9. Kondo Keiko, Kanenaga Ryoko, Tanaka Yoshinori, Hotta Kunimoto, Arakawa Shinichi. The neutralizing effect of mouth rinsing with alkaline electrolyzed water on different regions of the oral cavity acidified by acidic beverages(和訳中) Journal of Oral Science. 2022.01; 64 (1): 17-21. ( ichushi )

  10. Yuka Shichiri-Negoro, Chiaki Tsutsumi-Arai, Kazuhito Satomura, Shinichi Arakawa, Noriyuki Wakabayashi. Ozone ultrafine bubble water inhibits the early formation of Candida albicans biofilms PLOS ONE. 2021.12;

  11. Yuka Shichiri-Negoro, Yuki Arai, Chiaki Tsutsumi-Arai, Kazuhito Satomura, Shinichi Arakawa, Noriyuki Wakabayashi.. Ozone ultrafine bubble water inhibits the early formation of Candida albicans biofilms PLOS ONE. 2021.12;

  12. Machiko Kawasaki, Yuichi Ikeda, Eri Ikeda, Momoko Takahashi, Daiki Tanaka, Yasuaki Nakajima, Shinichi Arakawa, Yuichi Izumi, and Satoshi Miyake. Oral Infectious Bacteria in Dental Plaque and Saliva as Risk Factors in Patients with Esophageal Cancer Cancer. 2021.02; 127 (4): 512-519. ( PubMed, DOI )

  13. 渡辺 数基, 大杉 勇人, 前川 祥吾, 佐々木 直樹, 芝 多佳彦, 片桐 さやか, 荒川 真一. 創傷治癒モデルマウスにおける炎症因子を介したオゾンウルトラファインバブル水の効果(Ozone Ultrafine Bubble Water Improves Wound Healing via Modification of Inflammation) 口腔病学会雑誌. 2019.07; 86 (2): 25-35. ( ichushi )

  14. Watanabe K, Ohsugi Y, Maekawa S, Sasaki N, Shiba T, Katagiri S, Arakawa S. Ozone Ultrafine Bubble Water improves wound healing via modification of inflammation Journal of the Stomatological Society. 2019.07; 86 (2): 25-34.

  15. Anongwee Leewananthatwet, Shinichi Arakawa, Tokuju Okano, Ryo Daitoku Kinoshita, Hiroshi Ashida, Yuichi Izumi, Toshihiko Suzuki. Ozone ultrafine bubble water induces the cellular signaling involved in oxidative stress responses in human periodontal ligament fibroblasts Science and Technology of Advanced Materials . 2019.05; 20 (1): 589-598. ( DOI )

  16. Atsushi Oishi, Hitoyata Shimokawa, Eri Sakaniwa, Masayoshi Takahashi, Michiyo Miyashin, Shinichi Arakawa. Oxygen and air nanobubbles in water inhibit proliferation of dental follicle stem cells in vitro Journal of Dental Health Oral Disorders & Therapy. 2018.11; 9 (6): 460-462. ( DOI )

  17. Akiyama Masato, Takahashi Atsushi, Momozawa Yukihide, Arakawa Satoshi, Miya Fuyuki, Oshima Yuji, Yasuda Miho, Yoshida Shigeo, Yanagi Yasuo, Tanaka Koji, Ogura Yuichiro, Takahashi Kanji, Fujisawa Kimihiko, Kadonosono Kazuaki, Ishibashi Tatsuro, Sonoda Koh-hei. Genome-wide association study for response to ranibizumab therapy in 919 individuals with age-related macular degeneration INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2018.07; 59 (9):

  18. Leewananthawet Anongwee, Arakawa Shinichi, Okano Tokuju, Ashida Hiroshi, Izumi Yuichi, Suzuki Toshihiko. in vitroにおけるオゾン微細泡の生物学的影響の評価(Evaluation the biological effects of Ozone Ultrafine-Bubble Water in vitro) 日本歯周病学会会誌. 2018.05; 60 (春季特別): 135. ( ichushi )

  19. Shinichi Arakawa, Mitsuru Sugisawa, Anongwee Leewanthawet. Application of ozone nanobubble water (ONBW) to peri-implantitis treatment Dentistry. 2017.12; 7 (12): 463-468. ( DOI )

  20. M Doino, M Yokoyama, Y Sasaki, K Kondo, Y Yasuda, S Arakawa. Evaluation of the relationship between salivary concentration of anti-heat shock protein immunoglobulin and clinical manifestations of Behçet's disease. SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2017.09; 46 (5): 381-387. ( PubMed, DOI )

  21. H. Otuska, S. Arakawa, A. Kinoshita, K. Shinada, et al. . Development of an interprofessional education program where dental hygiene students instruct medical and dental students. Journal of Dental Education. 2016.12; 89 (9): 1062-1070.

  22. Shinichi Arakawa. Ozone antiseptic shows potential for treating severe gum infections Asia Research News 2015. 2015.05;

  23. Akiko Endo, Nachiko Ogata, Takayasu Watanabe, Takashi Nozawa, Chihiro Aikawa, Fumito Maruyama, Shinichi Arakawa, Yuichi Izumi, Ichiro Nakagawa. Comparative genome analysis and identification of competitive and cooperative interactions in a polymicrobial disease The ISME Journal . 2014.08; 9 624-642.

  24. Sae Hayakumo, Shinichi Arakawa, Masayoshi Takahashi, Keiko Kondo, Yoshihiro Mano and Yuichi Izumi. Effects of ozone nano-bubble water on periodontopathic bacteria and oral cells - in vitro studies Science and Technology of Advanced Materials. 2014; 15 1-7.

  25. Akiko Endo, Nachiko Ogata, Takayasu Watanabe, Takashi Nozawa, Chihiro Aikawa, Fumito Maruyama, Shinichi Arakawa, Yuichi Izumi and Ichiro Nakagawa. Comparative genome analysis and identification of competitive and cooperative interactions in a polymicrobial disease The ISME Journal. 2014; 1-14.

  26. Hayakumo S, Arakawa S, Yoshihiro Mano, Yuichi Izumi.. Clinical and microbiological effects of ozone nano-bubble water irrigation as an adjunct to mechanical subgingival debridement in periodontitis patients in a randomized controlled trial. Clin Oral Invest.. 2013.05; 17 379-388.

  27. Onishi H1, Arakawa S, Nakajima T, Izumi Y.. Levels of specific immunoglobulin G to the forsythia detaching factor of Tannerella forsythia in gingival crevicular fluid are related to the periodontal status. J Periodontal Res. 2010.01; 45 (5): 672-680. ( PubMed, DOI )

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Books etc 【 display / non-display 】

  1. Nozaki K, Saleh O, Arakawa S, Miura H. Water-Formed Deposits Fundamentals and Mitigation Strategies. 2022.03 Novel Technologies to prevent dental plaque and calculus

  2. Shinichi Arakawa. Ultrafine Bubbles. Jenny Stanford Publishing Pte.， 2021.11 Dental Application of Ozone Ultrafine Bubble Water (ISBN : 978-1-003-14195-2 )

  3. S. Arakawa, S .Hayakumo, Y. Mano and Y. Izum. 12.3 Clinical Application of Ozone Nanobubble Water to Periodontal Treatment. 2014.06

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Conference Activities & Talks 【 display / non-display 】

  1. Shinichi Arakawa. Basic property and clinical application of the ozone ultrafine bubble water (OUFBW). International Session of KSTU 2022 2022.10.29 Kore (Web)

  2. 杉澤　満、荒川真一. オゾンウルトラファインバブル水 を用いて改善した歯性上顎洞炎（症例報告）. 日本有病者歯科医療学会学術大会 2022.04.30

  3. 遠井　政行、近藤　真啓、荒川　真一、網干　博文. ショウジョウバエの糖質摂食を誘導するドパミン作動性ニューロンの探索. 2021年度第44回日本分子生物学会年会 2021.12.01 横浜

  4. 荒川真一. 高齢者に対する口腔衛生・機能管理. 令和元年度愛媛県前科術生士会第51司第5次生涯研修市I］度専門研修会 2020.12.15 愛媛県松山市堀之内

  5. Shinichi Arakawa. Ozone Ultrafine Bubble Water Clinical utilization and biological effects. Nanobubble 2018 2018.10.18 Suzhou, CHINA

  6. Shinichi Arakawa. Ozone Ultrafine Bubble Water (OUFBW) Basic characteristic and Clinical application. 上海市医学会第11回物理医学及び健康回復研究学術活動 2018年度委員会会議 2018.10.17 上海市第一人民病院

  7. Shinichi Arakawa. Basic characters and clinical application of Ozone Ultrafine bubble water. 上海市医学会第11回物理医学及び健康回復研究学術活動 2018.10.17 上海市第一人民病院

  8. Anongwee Leewananthawet, Shinichi Arakawa, Tokuju Okano, Yuichi Izumi, Toshihiko Suzuki. Evaluation of the biological effects of Ozone Ultrafine-Bubble Water in vitro. 第61回春季日本歯周病学会学術大会 2018.06.01 東京

  9. Arakawa S.. The clinical utilization of Ozone Ultrafine Bubble Water to get symbiosis. 2018.05.08

  10. Shinichi Arakawa. Relationship between oral health and systemic condition. International Conference On Dentistry and Integrated Medicine 2018.05.08 Tokyo, Japan

  11. Shinichi Arakawa. Clinical application of Ozone nano-bubble water -periodontitis & peri-implantitis- . 2017.04.19 Dental College, Gulf Medical University (UAE)

  12. 荒川真一. Clinical Application of Ozone Nano-Bubble Water (NBW3) to Peri-implantitis Treatment. The 24th International Conference and Exhibition on Dentistry & Oral Care 2017.04.17 Dubai, UAE

  13. Watanabe T. ,Yasuda M,. Kondo K., Arakawa S.,. Evaluation for the method of intervension for oaral health improvement for people with disabilities at the day care center.. The Stomatological Society,Japan 2016.11.26 Tokyo Medical and Dental University

  14. Jun Tsuruta,Kanako Noritake, Koji Mizutani, Naoko Seki,Keiko Kondo, Shinichi Arakawa,Kouji Araki. Implementing a new IPW course in the dental student clinic. Peking University School of Stomatology・Tri-university 2016.10.27 Peking University School of Stomatology

  15. Jun Tsuruta, Kanako Noritake, Kouji Mizutani, Naoko Seki, Keiko Kondou, Shinichi Arakawa, Kouji ARAKI. A new course Working in a team . SEAADE Annual Scientific Meeting 2016.09.08 Ho Chi Minh city, Vietnam

  16. Atsushi Oishi, Hitoyata Shimokawa, Wit Yee Wint, Shinichi Arakawa, Michiyo Miyashin. Effects of Nanobubble water on human cells derived from impacted supernumerary teeth. 10th Biennial Conference of the Pediatric Dentistry Association of Asia in conjunction with 54th Annual Conference of the Japanese Society of Pediatric Dentistry 2016.05.26 Tokyo

  17. Ode T, Podyma-Inoue K, Arakawa S, Yokoyama M, Izumi Y. Intracellular cholesterol trafficking is involved in osteoblastic differentiation of MC3T3－E1 cells. 57th Annual meeting of Japanese society of periodontology, International conference 2015.05.15

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Awards & Honors 【 display / non-display 】

  • Advanced Education System Development(Kanako Noritake)，Japanese Dental Education Association，2017.07

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Performance of duties 【 display / non-display 】

  • ，2017.04 - Now

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