Personnel Information

写真a

KARASUYAMA Hajime


Job title

Distinguished Professor

Laboratory Address

1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519

Laboratory Phone number

+81-3-5803-5162

Laboratory Fax number

+81-3-3814-7172

Mail Address

karasuyama.mbch@tmd.ac.jp

Homepage URL

http://immune-regulation.org/index.php?id=27

Research Areas, Keywords

allergy, basophil, B cell development, immunodeficiency, autoimmune, infection

Graduating School 【 display / non-display

  • Tokyo Medical and Dental University, Faculty of Medicine, 1978, Graduated

Graduate School 【 display / non-display

  • The University of Tokyo, Graduate School, Division of Medical Sciences, Doctor's Course, 1984, Completed

Degree 【 display / non-display

  • MD., PhD., The University of Tokyo

Campus Career 【 display / non-display

  • 2000.01
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Environmental Response, Immune Regulation, Professor
  • 2008.04
    -
    2014.03
    Tokyo Medical and Dental University, Executive Vice President, Deputy Director
  • 2014.04
    -
    2020.03
    Tokyo Medical and Dental University, Board Member, Executive Director
  • 2020.04
    -
    Now
    Tokyo Medical and Dental University, , , Distinguished Professor

External Career 【 display / non-display

  • 1978 Tokyo Medical and Dental University School of Medicine MD.1978,
  • 1980-1984 Postgraduate, Department of Immunology, Faculty of Medicine, University of Tokyo,
  • PhD., 1984.,
  • 1984-1987 Scientific member, Basel Institute for Immunology, Basel, Switzerland,
  • 1987-1990 Research Associate, Department of Immunology, Faculty of Medicine, University of Tokyo,

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Academic Society Affiliations 【 display / non-display

  • Japanese Society for Immunology

  • Japanese Society of Allergology

  • The Molecular Biology Society of Japan

  • Japanese Cancer Association

  • Japanese Society of Hematology

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Academic Activity 【 display / non-display

  • Japanese Society for Immunology Board member
  • Japanese Society of Allergology Board of representatives

Research Areas 【 display / non-display

  • Immunology

  • Cell biology

  • Collagenous pathology/Allergology

 

Research Theme 【 display / non-display

  • Genetic origins and pathogenesis of primary immunodeficiencies

  • Roles of basophils in protective immunity, immune regulation and allergy

  • Cellular and molecular basis of chronic allergic inflammation

  • Molecular mechanisms for regulation of lymphocyte development

Published Papers & Misc 【 display / non-display

  • Yang Y, Nagai S, Kang S, Xia Y, Kawano Y, Miyake K, Karasuyama H, Azuma M. Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting. International immunology. 2020.07; 32 (8): 509-518. ( PubMed, DOI )

  • Yamanishi Yoshinori, Mogi Kotone, Takahashi Kazufusa, Miyake Kensuke, Yoshikawa Soichiro, Karasuyama Hajime. Skin-infiltrating basophils promote atopic dermatitis-like inflammation via IL-4 production in mice ALLERGY. 2020.05; ( PubMed, DOI )

  • Nishimura Yuya, Fukuda Yota, Okonogi Toya, Yoshikawa Soichiro, Karasuyama Hajime, Osakabe Naomi, Ikegaya Yuji, Sasaki Takuya, Adachi Takahiro. Dual real-time in vivo monitoring system of the brain-gut axis BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2020.04; 524 (2): 340-345. ( PubMed, DOI )

  • Lin YH, Tahara-Hanaoka S, Nagai K, Yoshikawa S, Kubo M, Shibayama S, Karasuyama H, Shibuya A. Selective suppression of oral allergen-induced anaphylaxis by Allergin-1 on basophils in mice. International Immunology. 2019.12; 32 (3): 213-219. ( PubMed, DOI )

  • Kashiwakura J, Ando T, Karasuyama H, Kubo M, Matsumoto K, Matsuda T, Kawakami T. The basophil-IL-4-mast cell axis is required for food allergy. Allergy. 2019.10; 74 (10): 1992-1996. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Takahiro Adachi, Taro Watabe, Takashi Nagaishi, Mamoru Watanabe, Hajime Karasuyama, Soichiro Yoshikawa. IgA-deficiency causes spontaneous enteritis.. The 48th Annual Meeting of the Japanese Society for Immunology 2019.12.13 Hamamatsu(Japan)

  • Adachi Takahiro, Watabe Taro, Nagaishi Takashi, Watanabe Mamoru, Karasuyama Hajime, Yoshikawa Soichiro. Skin-Mucosal Inflammation IgA-deficiency causes spontaneous enteritis(和訳中). 日本免疫学会総会・学術集会記録 2019.11.01

  • Lin Yu-hsien, Tahara-Hanaoka Satoko, Yoshikawa Soichiro, Shibayama Shiro, Karasuyama Hajime, Shibuya Akira. Allergy-2: Anaphylaxis, airway inflammation/asthma and others (except dermtitis) Selective suppression of oral allergen-induced anaphylaxis by Allergin-1(和訳中). 日本免疫学会総会・学術集会記録 2019.11.01

  • Ito Junya, Miyake Kensuke, Shichino Shigeyuki, Yamanishi Yoshinori, Karasuyama Hajime. Allergy-2: Anaphylaxis, airway inflammation/asthma and others (except dermtitis) Identification of immature-type basophils that are distinguishable from mature ones in terms of surface phenotype and activation property(和訳中). 日本免疫学会総会・学術集会記録 2019.11.01

  • Miyake Kensuke, Yoshikawa Soichiro, Yamanishi Yoshinori, Karasuyama Hajime. Allergy-1: skin inflammation Monocyte-derived M2-like macrophages induced by activated basophils dampen IL-1α-mediated aggravation of allergic inflammation(和訳中). 日本免疫学会総会・学術集会記録 2019.11.01

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Awards & Honors 【 display / non-display

  • Tokyo Medical and Dental University President Award (Hajime Karasuyama),Tokyo Medical and Dental University,2014.10

  • The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology, Prizes for Science and Technology (Research Category) (Hajime Karasuyama),Ministry of Education, Culture, Sports, Science and Technology,2014.04

 

Campus class subject 【 display / non-display

  • Immunology

  • Immunology

  • Biochemistry