Personnel Information

写真a

SAEGUSA Hironao


Job title

Assistant Professor

Laboratory Phone number

+81-3-5803-5170

Mail Address

The inquiry by e-mail is 《here

Graduating School 【 display / non-display

  • The University of Tokyo, Faculty of Science, 1988.03, Graduated

Graduate School 【 display / non-display

  • Nagoya University, Graduate School, Division of Natural Science, Doctor's Course, 1993.03, Completed

Degree 【 display / non-display

  • Ph.D, Nagoya University

Campus Career 【 display / non-display

  • 1900.01
    -
    2018.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Cognitive and Behavioral Medicine, Pharmacology and Neurobiology, Assistant Professor
  • 2018.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Cognitive and Behavioral Medicine, Pharmacology and Neurobiology, Assistant Professor

Research Areas 【 display / non-display

  • Neurochemistry/Neuropharmacology

 

Published Papers & Misc 【 display / non-display

  • Saegusa Hironao, Li Xu, Wang Xinshuang, Kayakiri Midori, Tanabe Tsutomu. Knockdown of microglial Cav2.2 N-type voltage-dependent Ca(2+)channel ameliorates behavioral deficits in a mouse model of Parkinson's disease FEBS LETTERS. 2020.06; ( PubMed, DOI )

  • Huntula, S., Wang, X., Saegusa, H. and Tanabe, T.. Involvement of N-type Ca2+ channel in microglial activation and its implications to aging-induced exaggerated cytokine response. Cell Calcium. 2019.07; 82 102059. ( DOI )

  • Wang, X., Saegusa, H., Huntula, S. and Tanabe, T. . Blockade of microglial Cav1.2 Ca2+ channel exacerbates the symptoms in a Parkinson’s disease model. Scientific Reports . 2019.06; 9 (9138): ( DOI )

  • Daisuke Kondo, Hironao Saegusa, Tsutomu Tanabe. Involvement of phosphatidylinositol-3 kinase/Akt/mammalian target of rapamycin/peroxisome proliferator-activated receptor γ pathway for induction and maintenance of neuropathic pain. Biochem. Biophys. Res. Commun.. 2018.05; 499 (2): 253-259. ( PubMed, DOI )

  • Hironao Saegusa, Tsutomu Tanabe. N-type voltage-dependent Ca2+ channel in non-excitable microglial cells in mice is involved in the pathophysiology of neuropathic pain. Biochem. Biophys. Res. Commun.. 2014.07; 450 (1): 142-147. ( PubMed, DOI )

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Books etc 【 display / non-display

  • Hironao Saegusa, Tsutomu Tanabe. Pharmacology of Calcium Channels. Kluwer Academic / Plenum Publishers, 2004.09 Genetic approaches to the elucidation of calcium channel functions in vivo.