Personnel Information

写真a

TANABE Tsutomu


Job title

Professor

Laboratory Address

Bunkyo-ku, Yushima 1-5-45 Tokyo 113-8519 Japan

Laboratory Phone number

+81-3-5803-5167

Laboratory Fax number

+81-3-5803-0122

Mail Address

t-tanabe.mphm@tmd.ac.jp

Homepage URL

http://www.tmd.ac.jp/med/mphm/eYakuri.HTM

Research Areas, Keywords

calcium channel, neuropathic pain, neurological disorder, adult stem cell, ion channelopathy, morphine, tolerance, gene knockout mouse, SCA6, pain, microglia, macrophage, miRNA, neurodegenerative disease, inflammatory disease, Parkinson's disease, Huntington's disease, Inflammatory bowel diseas, Rheumatoid arthritis

Graduating School 【 display / non-display

  • Kyoto University, Faculty of Agriculture, Food Science and Technology, 1979.03, Graduated

Graduate School 【 display / non-display

  • Kyoto University, Graduate School, Division of Agriculture, Food Science and Technology, Master's Course, 1981.03, Completed

  • Kyoto University, Graduate School, Division of Medicine, Medical Chemistry, Doctor's Course, 1987.03, Completed

Degree 【 display / non-display

  • MA

  • PhD, Kyoto University

Campus Career 【 display / non-display

  • 1995.04
    -
    2018.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Cognitive and Behavioral Medicine, Pharmacology and Neurobiology, Professor
  • 2018.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Cognitive and Behavioral Medicine, Pharmacology and Neurobiology, Professor

External Career 【 display / non-display

  • 1987.04
    -
    1992.03
    Kyoto University , School of Medicine, Department of Medical Chemistry, Assistant Professor
  • 1988.04
    -
    1991.03
    Colorado State University, College of Veterinary Medicine and Biomedical Sciences, Visiting Professor
  • 1991.04
    -
    1992.03
    Stanford University, Department of Molecular and Cellular Physiology, School of Medicine, Visiting Assistant Professor
  • 1992.04
    -
    1995.06
    Yale University, Department pf Cellular and Molecular Physiology, School of Medicine, Assistant Professor
  • 1992.04
    -
    1995.12
    Howard Hughes Medical Institute (HHMI), Investigator

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Academic Society Affiliations 【 display / non-display

  • The Japanese Pharmacological Society Councilor

  • Society for Neuroscience

Research Areas 【 display / non-display

  • Neurochemistry/Neuropharmacology

  • Neurophysiology / General neuroscience

  • General pharmacology

  • General medical chemistry

 

Research Theme 【 display / non-display

  • Microglial Ca channel function in Neuroinflammation/Neurodegenerative diseases, 2000.04 - Now

  • Energy metabolic imaging at single cell level of neuron, microglia and astrocyte in the degenerative area of the mouse model of various neurodegenerative diseases, 2000.04 - Now

  • Energy metabolic imaging at single cell level of cancer stem cell/cancer cell using Bioluminescence and FRET and Imaging, 2000.04 - Now

  • Neural basis of conscious affects (liking and disgust), 2000.04 - Now

  • Molecular basis of Calcium channelopathy, 2000.04 - Now

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Published Papers & Misc 【 display / non-display

  • Mikeli Maimaiti, Fujikawa Makoto, Nagahisa Kai, Yasuda Shuhei, Yamada Natsuhiko, Tanabe Tsutomu. Contribution of GPD2/mGPDH to an alternative respiratory chain of the mitochondrial energy metabolism and the stemness in CD133-positive HuH-7 cells GENES TO CELLS. 2020.01; 25 (2): 139-148. ( PubMed, DOI )

  • Tanaka, D.H. and Tanabe, T. . CHANging consciousness epistemically (CHANCE): An empirical method to convert the subjective content of consciousness into scientific data. J. Mind Behav. . 2019.12; 40 (3,4): 177-190.

  • Huntula, S., Wang, X., Saegusa, H. and Tanabe, T.. Involvement of N-type Ca2+ channel in microglial activation and its implications to aging-induced exaggerated cytokine response. Cell Calcium. 2019.07; 82 102059. ( DOI )

  • Tanaka DH, Li S, Mukae S, Tanabe T. Genetic Access to Gustatory Disgust-Associated Neurons in the Interstitial Nucleus of the Posterior Limb of the Anterior Commissure in Male Mice. Neuroscience. 2019.06; 413 45-63. ( PubMed, DOI )

  • Wang, X., Saegusa, H., Huntula, S. and Tanabe, T. . Blockade of microglial Cav1.2 Ca2+ channel exacerbates the symptoms in a Parkinson’s disease model. Scientific Reports . 2019.06; 9 (9138): ( DOI )

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Conference Activities & Talks 【 display / non-display

  • Contribution of GPD2/mGPDH to an alternative respiratory chain of the mitochondrial energy metabolism and the stemness in CD133-positive HuH-7 cells. 2019.12.03

Awards & Honors 【 display / non-display

  • 1989 Japanese Biochemical Society Promotion of Science Award (Nihon Seikagakukai Shoureishou),1989

 

Campus class subject 【 display / non-display

  • Pharmacology,1995 - Now

  • Neuroscience (Basic),1995 - Now