Personnel Information

写真a

HATA Yutaka


Job title

Professor

Laboratory Address

1-5-45 Yushima, Bunkyo-ku, Tokyo

Homepage URL

http://www.tmd.ac.jp/english/mbc/index.html

Research Areas, Keywords

cancer signal transduction apoptosis cell cycle oncogene tumor suppressor muscle macrophage

Graduating School 【 display / non-display

  • The University of Tokyo, Faculty of Medicine, 1982, Graduated

Degree 【 display / non-display

  • Doctor of medicine

Campus Career 【 display / non-display

  • 1900.01
    -
    2018.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Medical Biochemistry, Professor
  • 2018.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Medical Biochemistry, Professor

Research Areas 【 display / non-display

  • General medical chemistry

  • Pathological medical chemistry

 

Research Theme 【 display / non-display

  • Molecular dissection of the singal transduction pathway that regulates cell proliferation, cell polarity and cell death

Published Papers & Misc 【 display / non-display

  • Shimizu T, Nakamura T, Inaba H, Iwasa H, Maruyama J, Arimoto-Matsuzaki K, Nakata T, Nishina H, Hata Y. The RAS-interacting chaperone UNC119 drives the RASSF6-MDM2-p53 axis and antagonizes RAS-mediated malignant transformation. The Journal of biological chemistry. 2020.06; ( PubMed, DOI )

  • Kodaka Manami, Mao Fengju, Arimoto-Matsuzaki Kyoko, Kitamura Masami, Xu Xiaoyin, Yang Zeyu, Nakagawa Kentaro, Maruyama Junichi, Ishii Kana, Akazawa Chihiro, Oyaizu Takuya, Yamamoto Naoki, Ishigami-Yuase Mari, Tsuemoto Nozomi, Ito Shigeru, Kagechika Hiroyuki, Nishina Hiroshi, Hata Yutaka. Characterization of a novel compound that promotes myogenesis via Akt and transcriptional co-activator with PDZ-binding motif (TAZ) in mouse C2C12 cells PLOS ONE. 2020.04; 15 (4): e0231265. ( PubMed, DOI )

  • Watanabe Naoshi, Morimatsu Masatoshi, Fujita Ayano, Teranishi Mika, Sudevan Surabhi, Watanabe Masaru, Iwasa Hiroaki, Hata Yutaka, Kagi Hiroyuki, Nishiyama Masayoshi, Naruse Keiji, Higashitani Atsushi. Increased hydrostatic pressure induces nuclear translocation of DAF-16/FOXO in C. elegans BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2020.03; 523 (4): 853-858. ( PubMed, DOI )

  • 江欣 亮, 丸山 順一, 畑 裕. Heat shock-mediated regulation of transcriptional co-activator YAP1(和訳中) 日本生化学会大会プログラム・講演要旨集. 2019.09; 92回 [1P-173]. ( ichushi )

  • 丸山 順一, 椙村 春彦, 畑 裕. Doublecortin-like kinase 1はDNA損傷修復機構を抑制し染色体不安定化を誘導する(Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability) 日本癌学会総会記事. 2019.09; 78回 P-3210. ( ichushi )

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Books etc 【 display / non-display

  • Xu X, Kodaka M, Iwasa H, Hata Y. Encyclopedia of Signaling Molecules MAGI2/S-SCAM. SPringer, MAGI2

  • Kodaka M, Xu X, Yang X,Maruyama J, Hata Y. SPringer Protocol Appication of split-GFP reassembly assay to the study of the in vitro myogenesis and myofusion.. Springer, Application of split-GFP reassembly assay to the study of the in vitro myogenesis and myofusion.

  • Iwasa H, Shimizu T, Hata Y.. Encyclopedia of Signaling Molecules RASSF6. Springer, RASSF6 (ISBN : 978-1-4419-0460-7)

Conference Activities & Talks 【 display / non-display

  • Yutaka Hata. New tricks that regulate YAP and TAZ. Telluride Science Research Center Workshop 2019.06.12 Telluride, Collardo, USA

  • Hossain Shakhawoat, 岩佐宏晃, 畑裕. RASSF6腫瘍抑制タンパク質は網膜芽細胞腫タンパク質を介してアポトーシスと細胞周期を制御する. 第77回日本癌学会総会 2018.09

  • Yutaka Hata. Transcriptional coactivator with PDZ-binding motif (TAZ), a potential target for interventions against muscle-wasting disorders. Neuroscience Symposium 2015 2015.10.23

Patents 【 display / non-display

  • Myogenesis Promotor, Muscle Atrophy Inhibitor, Medical Composition and Taz Activator

    Patent Number: 10653672

 

Campus class subject 【 display / non-display

  • medical biochemistry