Personnel Information

写真a

SHINOMURA Tamayuki


Job title

Associate Professor

Mail Address

t.shinomura.trg@tmd.ac.jp

Research Areas, Keywords

connective tissue, cartilage, proteoglycan, collagen, extracellular matrix

Degree 【 display / non-display

  • Doctor of Philosophy, Nagoya University

Campus Career 【 display / non-display

  • 2000.04
    -
    2018.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Connective Tissue Regeneration, Associate Professor
  • 2018.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Connective Tissue Regeneration, Associate Professor

Academic Society Affiliations 【 display / non-display

  • The Japanese Society of Cartilage Metabolism

  • The Japanese Society for Connective Tissue Research

  • The Japanese Biochemical Society

Academic Activity 【 display / non-display

  • 2001.04
    -
    Now
    The Japanese Society of Cartilage Metabolism Director

Research Areas 【 display / non-display

  • Functional biochemistry

  • Orthopaedic surgery

  • Functional basic dentistry

 

Published Papers & Misc 【 display / non-display

  • Koke, H., Nishida, Y., Shinomura, T., Zhuo, L., Hamada, S., Ikuta, K., Ito, K., Kimata, K., Ushida, T., Ishiguro, N.. Forced expression of KIAA1199, a novel hyaluronidase, inhibits tumorigenicity of low-grade chondrosarcoma Journal of Orthopedic Research. 2020.02; ( DOI )

  • Giang Thi Hien Nham, Xiang Zhang, Yoshinori Asou, Tamayuki Shinomura. Expression of type II collagen and aggrecan genes is regulated through distinct epigenetic modifications of their multiple enhancer elements. Gene. 2019.07; 704 134-141. ( PubMed, DOI )

  • Miyazaki Y, Horie A, Tani H, Ueda M, Okunomiya A, Suginami K, Kondoh E, Baba T, Konishi I, Shinomura T, Sato Y. Versican V1 in human endometrial epithelial cells promotes BeWo spheroid adhesion in vitro. Reproduction. 2019.01; 157 (1): 53-64. ( PubMed, DOI )

  • Hamada S, Nishida Y, Zhuo L, Shinomura T, Ikuta K, Arai E, Koike H, Kimata K, Ushida T, Ishiguro N. Suppression of hyaluronan synthesis attenuates the tumorigenicity of low-grade chondrosarcoma Journal of Orthopaedic Research. 2018.06; 36 (6): 1573-1580. ( PubMed, DOI )

  • Miyazaki Yumiko, Horie Akihito, Sato Yukiyasu, Tani Hirohiko, Ueda Masashi, Okunomiya Asuka, Matsumura Noriomi, Shinomura Tamayuki. Effects of versican V1 on human embryo attachment in an in vitro implantation model The Journal of Obstetrics and Gynaecology Research. 2017.12; 43 (12): 2016. ( ichushi )

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Conference Activities & Talks 【 display / non-display

  • Nham, G.T.H, Zhang, X., Shinomura, T.. Expression of type II collagen and aggrecan genes is regulated through distinct epigenetic modifications of their multiple enhancer elements. 日本生化学会 2019.09.19

  • Tamayuki Shinomura. Expression of type II collagen and aggrecan genes is regulated through the distinct epigenetic modification of multiple enhancer elements. Gordon Research Conference; Cartilage Biology and Pathology 2019.03.21 Galveston, TX, USA

  • 張響、ジャン ニャン、篠村多摩之. II型コラーゲンの遺伝子発現を制御するエンハンサー特異的転写因子の同定. 第32回日本軟骨代謝学会 2019.03.01 大阪

  • 小池宏、西田佳弘、篠村多摩之、大河原美静、大野欽司、卓麗聖、木全弘治、石黒直樹. KIAA1199 活性の抑制を介して炎症性関節炎を抑制する薬剤開発. 第32回日本軟骨代謝学会 2019.03.01 大阪

  • Zhang Xiang, Nham Thi Hien Giang, Tamayuki Shinomura. Identification of an enhancer-specific transcription factor regulating type II collagen gene expression. The 6th Tri-University Consortium on Oral Science and Education 2018.11.30 Tokyo, Japan

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Awards & Honors 【 display / non-display

  • Ohtaka Award,1995