Personnel Information

写真a

HOMMA Hidenori


Job title

Project Assistant Professor

Graduating School 【 display / non-display

  • University of Tsukuba, Third Cluster of College, 2004.03, Graduated

Graduate School 【 display / non-display

  • University of Tsukuba, Doctor's Course, 2009.03, Completed

Campus Career 【 display / non-display

  • 2013.04
    -
    Now
    Tokyo Medical and Dental University, Medical Research Institute, Pathophysiology, Neuropathology, Project Assistant Professor
  • 2013.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Cognitive and Behavioral Medicine, Neuropathology, Project Assistant Professor
 

Published Papers & Misc 【 display / non-display

  • Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H. Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. eNeuro. 2018.07; 5 (4): ( PubMed, DOI )

  • Kyota Fujita, Xigui Chen, Hidenori Homma, Kazuhiko Tagawa, Mutsuki Amano, Ayumu Saito, Seiya Imoto, Hiroyasu Akatsu, Yoshio Hashizume, Kozo Kaibuchi, Satoru Miyano, Hitoshi Okazawa. Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology. Nat Commun. 2018.01; 9 (1): 433. ( PubMed, DOI )

  • Kyota Fujita, Ying Mao, Shigenori Uchida, Xigui Chen, Hiroki Shiwaku, Takuya Tamura, Hikaru Ito, Kei Watase, Hidenori Homma, Kazuhiko Tagawa, Marius Sudol, Hitoshi Okazawa. Developmental YAPdeltaC determines adult pathology in a model of spinocerebellar ataxia type 1. Nat Commun. 2017.11; 8 (1): 1864. ( PubMed, DOI )

  • Chen X., Mao Y., Xu M., Fujita K., Motoki K., Sasabe T., Homma H., Tagawa K., Tamura T., Okazawa H.. Targeting tead/yap-transcription-dependent necrosis, triad, ameliorates Huntington's disease pathology JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 219. ( DOI )

  • Fujita K., Motoki K., Tagawa K., Chen X., Hama H., Nakajima K., Homma H., Tamura T., Miyawaki A., Okazawa H.. HMGB1 triggers neurite degeneration via TLR4-MARCKS, and is a potential therapeutic target for alzheimer's disease JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 64-65. ( DOI )

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Conference Activities & Talks 【 display / non-display

  • Xigui Chen, Kanoh Kondo, Kazumi Motoki, Hidenori Homma, Hitoshi Okazawa. Fasting activates macroautophagy in neurons of AD mice but is insufficient to degrade amyloid-beta. 第57回日本神経学会学術大会 2016.05.19 神戸国際展示場(兵庫県神戸市)

  • Ito.H.,Shiwaki.H.,Yoshida.C.,Honma.H.,Chin.S.,Fujita.K.,Okazawa.H. Mutations in the PQBP1 gene prevent its interaction with the spliceosomal protein U5-15 kD. The 37th Annual Meeting of the Molecular Biology Society of Japan 2014.11.27 Pacifico Yokohama

  • Juliana Bosso Taniguchi, Kanoh Kondo, Kyota Fujita, Xigui Chen, Hidenori Homma , Ying Mao , Kazuhiko Tagawa , Hitoshi Okazawa.. RPA1 AMELIORATES SYMPTOMS OF MUTANT ATAXIN-1 KNOCK-IN MICE AND ENHANCE DNA DAMAGE REPAIR. XXIII World Congress of Neurology (WCN 2017) 合同開催:第58回日本神経学会学術大会・第23回世界神経学会議 2017.09.17 Kyoto International Conference Center (日本、京都)

  • Kyota Fujita, Kazumi Motoki, Kazuhiko Tagawa, Xigui Chen, Hiroshi Hama, Kazuyuki Nakajima, Hidenori Homma, Takuya Tamura, Atsushi Miyawaki, Hitoshi Okazawa.. HMGB1 TRIGGERS NEURITE DEGENERATION VIA TLR4-MARCKS, AND IS A POTENTIAL THERAPEUTIC TARGET FOR ALZHEIMER’S DISEASE. XXIII World Congress of Neurology (WCN 2017) 合同開催:第58回日本神経学会学術大会・第23回世界神経学会議 2017.09.17 Kyoto International Conference Center (日本、京都)

  • Xigui Chen, Mao Ying, Xu Min, Kyota Fujita, Kazumi Motoki, Toshikazu Sasabe, Hidenori Homma, Miho Murata, Kazuhiko Tagawa, Takuya Tamura, Kaye Julia, Steven Finkbeiner, Giovanni Blandino, Marius Sudol, Kanoh Kondo, Hitoshi Okazawa.. Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington's disease pathology. 第40回日本神経科学大会 2017.07.22 Kyoto International Conference Center (日本、京都)

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