Personnel Information

写真a

KOBAYAKAWA Takuya


Job title

Assistant Professor

Laboratory Address

2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-0062, Japan

Laboratory Phone number

+81-3-5280-8039

Laboratory Fax number

+81-3-5280-8039

Mail Address

The inquiry by e-mail is 《here

Homepage URL

http://www.tmd.ac.jp/i-mde/www/en/biomolecular/index1.html

Research Areas, Keywords

Synthetic Organic Chemistry, Medicinal Chemistry, Chemical Biology, Peptide Chemistry, Peptidomimetic Chemistry

Graduating School 【 display / non-display

  • Waseda University, School of Advance Science and Engineering, Department of Applied Chemistry, 2012.03, Graduated

Graduate School 【 display / non-display

  • Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Science and Technology Track, Master's Course, 2014.03, Completed

  • Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology Track, Doctor's Course, 2017.03, Completed

Degree 【 display / non-display

  • Doctor (Engineering), Tokyo Medical and Dental University

  • Master (Engineering), Tokyo Medical and Dental University

  • Bachelor (Engineering), Waseda University

Campus Career 【 display / non-display

  • 2012.04
    -
    2014.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Science and Technology, Graduate Student
  • 2014.04
    -
    2017.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology, Life Science and Technology, Medicinal Chemistry, Graduate Student
  • 2017.04
    -
    2017.09
    Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Biomolecular Chemistry, Medicinal Chemistry, Junior Associate Professor
  • 2017.10
    -
    Now
    Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Biomolecular Chemistry, Medicinal Chemistry, Assistant Professor

External Career 【 display / non-display

  • 2014.04
    -
    2016.03
    Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Research Assistant
  • 2015.04
    -
    2016.03
    Tokyo Kasei University,
  • 2016.04
    -
    2017.03
    Japan Society for the Promotion of Science, Research Fellowships for Young Scientists, Research Fellowships for Young Scientists
  • 2017.04
    -
    2017.09
    Japan Society for the Promotion of Science, Research Fellowships for Young Scientists, Research Fellowships for Young Scientists

Academic Society Affiliations 【 display / non-display

  • The Pharmaceutical Society of Japan

  • Japanese Society for Chemical Biology

  • The Society of Synthetic Organic Chemistry, Japan

  • The Japanese Peptide Society

  • American Chemical Society

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Academic Activity 【 display / non-display

  • 2013.06
     
     
    The 8th Annual Meeting of Japanese Society for Chemical Biology The 8th Annual Meeting of Japanese Society for Chemical Biology, Cooperation Staff
  • 2017.10
    -
    Now
    Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University Open Campus Committee
  • 2018.06
     
     
    The 13th Annual Meeting of Japanese Society for Chemical Biology The 13th Annual Meeting of Japanese Society for Chemical Biology, Cooperation Staff

Research Areas 【 display / non-display

  • Chemical pharmacy

  • Organic chemistry

  • Synthetic chemistry

  • Drug development chemistry

  • Chemical biology

Qualification Acquired 【 display / non-display

  • Hazardous Material Handler (first kind)

  • Usual Car License (first kind)

 

Published Papers & Misc 【 display / non-display

  • Takuya Kobayakawa, Hirokazu Tamamura. Development for peptidomimetic chemistry based on chloroalkene structures Journal of Synthetic Organic Chemistry, Japan. 2019.09; 77 (9): 904-911.

  • Takuya Kobayakawa, Kento Ebihara, Yuzuna Honda, Masayuki Fujino, Wataru Nomura, Naoki Yamamoto, Tsutomu Murakami, Hirokazu Tamamura. Dimeric C34 Derivatives Linked through Disulfide Bridges as New HIV-1 Fusion Inhibitors. Chembiochem. 2019.08; 20 (16): 2101-2108. ( PubMed, DOI )

  • Maeda K, Das D, Kobayakawa T, Tamamura H, Takeuchi H. Discovery and Development of anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication. Current topics in medicinal chemistry. 2019.07; ( PubMed, DOI )

  • Takuya Kobayakawa. Development for peptidomimetic chemistry utilizing the oxetanyl structure Journal of Synthetic Organic Chemistry, Japan; Review de Debut. 2019.07; 77 (7): 720-721.

  • Maxwell M Sakyiamah, Wataru Nomura, Takuya Kobayakawa, Hirokazu Tamamura. Development of a NanoBRET-Based Sensitive Screening Method for CXCR4 Ligands. Bioconjug. Chem.. 2019.05; 30 (5): 1442-1450. ( PubMed, DOI )

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Books etc 【 display / non-display

  • The Frontier of Peptide Drug Discovery. 2019.05 (ISBN : 978-4-7813-1417-4)

  • Synthesis Technology of Peptides, Nucleic Acids and Sugar Chains for Medium Molecule Drug Discovery. CMC Publishing Co.,Ltd., 2018.02 (ISBN : 978-4-7813-1320-7)

  • Hirokazu Tamamura, Takuya Kobayakawa, Nami Ohashi. Mid-size Drugs Based on Peptides and Peptidomimetics. Springer Singapore, 2018.01 (ISBN : 978-981-10-7691-6)

  • Takuya Kobayakawa, Tetsuo Narumi, Hirokazu Tamamura. Stereoselective Synthesis of Chloroalkene Dipeptide Isosteres Utilizing Organocopper Reagents. The Japanese Peptide Society, 2016.03

  • Takuya Kobayakawa, Tetsuo Narumi, Hirokazu Tamamura. Development of Efficient Synthetic Methodologies of Chloroalkene Dipeptide Isosteres. in "Peptide Science 2014," ed. by Akira Otaka, The Japanese Peptide Society, Osaka. The Japanese Peptide Society, 2015.03

Conference Activities & Talks 【 display / non-display

  • 村上努、海老原健人、小早川拓也、藤野真之、児玉栄一、玉村啓和. 二量体化HIV-1膜融合阻害剤の作用機構. 第33回日本エイズ学会学術集会・総会 2019.11.27 熊本

  • Elucidation of mechanism of HIV-1 fusion inhibitors developed by dimerization strategy. 第67回 日本ウイルス学会学術集会 2019.10.29 東京

  • 松田幸樹、小早川拓也、土屋亮人、服部真一朗、潟永博之、吉村和久、岡慎一、遠藤泰之、玉村啓和、満屋裕明、前田賢次. HIV潜伏感染再活性化を介してリザーバー細胞にアポトーシスを誘導するPKC活性化剤の同定. 第67回 日本ウイルス学会学術集会 2019.10.29

  • Maxwell M, Sakyiamah, Wataru Nomura, Takuya Kobayakawa, Hirokazu Tamamura. Development of a NanoBRET-based sensitive screening method for CXCR4 ligands . The 14th Annual Meeting of Japanese Society for Chemical Biology 2019.06.10 Aichi

  • Structure-activity relationship study of low molecular anti-HIV-1 agents based on Capsid protein of HIV-1. 2019.03.22

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Campus class subject 【 display / non-display

  • Practical Chemical Biology,2018 - Now

  • Development of Functional Molecules,2018 - Now

  • Introduction to Chemistry and Biology of Biofunctional Molecules,2018 - Now

External class subject 【 display / non-display

  • ,Tokyo Kasei University

  • ,Tokyo Kasei University

Performance of duties 【 display / non-display

  • ,2019.01

  • ,2019.01

  • ,2019.01

  • ,2018.08

  • ,2018.06

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Social Contribution 【 display / non-display

  • Frontier Research on Medicinal Chemistry of Mid-sized Molecules,Kanazawa, Japan,2018.03.28