Personnel Information

写真a

MIYAHARA Yuji


Job title

Professor

Birth date

1956

Laboratory Address

Institute of Biomaterials and Bioengineering Tokyo Medical and Dental University 2-3-10 Kanda-Surugadai, Chiyoda, Tokyo 101-0062, Japan

Laboratory Phone number

+81-3-5280-8095

Laboratory Fax number

+81-3-5280-8095

Mail Address

miyahara.bsr@tmd.ac.jp

Homepage URL

http://www.tmd.ac.jp/bsr/index.html

Graduating School 【 display / non-display

  • Tokyo Institute of Technology, Faculty of Engineering, Physical Electronics, 1980, Graduated

Graduate School 【 display / non-display

  • Tokyo Institute of Technology, Graduate School, Division of Science and Engineering, Electrical and Electronics Engineering, Doctor's Course, 1985, Completed

Degree 【 display / non-display

  • Dr. of Engineering, Tokyo Institute of Technology

Campus Career 【 display / non-display

  • 2010.09
    -
    Now
    Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Medical Devices, Bioelectronics, Professor
  • 2010.09
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology, Life Science and Technology, Bioelectronics, Professor
  • 2010.09
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology, Life Science and Technology, Bioelectronics, Professor

External Career 【 display / non-display

  • 1985 Central Research Laboratory, Hitachi Ltd.,
  • 1988-1989 Visiting researcher at Dept. of Organic Chemistry, ETH Zürich,
  • 1994 Senior researcher, Central Research Laboratory, Hitachi Ltd.,
  • 1998 Vice Department manager of Biosystem research department, Central Research Laboratory, Hitachi Ltd.,
  • 2000 Senior researcher, Biomedical Center, Hitachi High-technologies,

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Academic Activity 【 display / non-display

  • 2001 Oct., Member of the International Federation of Clinical Chemistry (IFCC) Working Group on Nanotechnology
  • 2002 Oct., Sub-committee chair, 2002 International Conference on Solid State Devices and Materials
  • 2002 May, Local Organizing Committee, 6th International Conference on Miniaturized Chemical and Biochemical Analysis System (μTAS2002)
  • 2003 Jan., 2003, Sub-committee chair, International Conference on Solid State Devices and Materials
  • 2003 Jan., Organizing committee, International Symposium on Fusion of Nano- and Bio- Technologies

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Research Areas 【 display / non-display

  • Nanomaterials chemistry

  • Biomedical engineering/Biomaterial science and engineering

 

Research Theme 【 display / non-display

  • An interdisciplinary area is explored and developed by integrating materials science and biological science. Novel biocompatible materials and functional bio-devices are developed for regenerative medicine, cell therapy, minimum-invasive surgery and clinical diagnostics. In the group of Yuji Miyahara, direct interaction between biomolecules and carriers in semiconductor materials has recently been investigated. For this purpose, an insulated gate field effect transistor (IGFET) has been used in combination with functional membranes. ,,The FET is one of the most important and fundamental devices in the integrated circuit. In the case of FET type biochemical sensors, species to be detected and its selectivity can be determined by the materials coated on the surface of the gate insulator. Ion sensors, biosensors and oxygen sensor have been developed using polymer membranes, immobilized enzyme membranes and a solid electrolyte thin film, respectively. ,,Recently, we have been investigating electrostatic detection of bio-molecular recognition using a biologically coupled field effect transistor (bio-FET). The principle of bio-FET is based on potentiometric detection of charge density change which is induced at a gate insulator/solution interface by specific bio-molecular recognition. In this scheme, the charge density change is directly transduced into electrical signal by the field effect. Based on this principle, various types of bio-FETs have been developed for detection of biomolecules

Published Papers & Misc 【 display / non-display

  • Chindanai Ratanaporncharoen, Miyuki Tabata, Natthapol Watanagool, Tatsuro Goda. Characterization and Optimization of Thermally Grown Iridium Oxide and Its Application to pH Sensors Sensors and Materials. 2018.05; 30 (5): 1175-1185. ( DOI )

  • Yukichi, Horiguchi, Tatsuro, Goda, Yuji, Miyahara. Simple functionalization method for single conical pores with a polydopamine layer. Applied Physics Express. 2018.04; 11 (4): 047001. ( DOI )

  • Chindanai Ratanaporncharoen, Miyuki Tabata, Yuichi Kitasako, Masaomi Ikeda, Tatsuro Goda, Akira Matsumoto, Junji Tagami, Yuji Miyahara. pH Mapping on Tooth Surfaces for Quantitative Caries Diagnosis Using Micro Ir/IrOx pH Sensor. Anal. Chem.. 2018.03; ( PubMed, DOI )

  • Enrico Tenaglia, Yuki Imaizumi, Yuji Miyahara, Carlotta Guiducci. Isothermal Multiple Displacement Amplification of DNA Templates in Minimally Buffered Conditions using Phi29 Polymerase Chemical Communications. 2018.02; 17 (57): 2158-2161. ( DOI )

  • Yukichi Horiguchi, Tatsuro Goda, Akira Matsumoto, Hiroaki Takeuchi, Shoji Yamaoka, Yuji Miyahara. Direct and Label-Free Influenza Virus Detection Based on Multisite Binding to Sialic Acid Receptors Biosens. Bioelectron.. 2017.06; 92 234-240.

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Conference Activities & Talks 【 display / non-display

  • Yuji Miyahara. Medical and dental applications of solid-state electrochemical sensors. 3rd Japan-Thailand Joint Symposium on Advanced Nanomaterials and Devices for Electronics and Photonics (JT-AND 2018) 2018.01.22 Chulalongkorn University, Bangkok, Thailand

  • Yuji Miyahara, Miyuki Tabata, Chindanai Ratanaporncharoen, Aoi Asano, Yuichi Kitasako, Masaomi Ikeda, Tatsuro Goda, Akira Matsumoto, Junji Tagami. Fabrication of needle type pH sensor for quantitative caries detection. European Advanced Materials Congress 2017 2017.08.22 Stockholm, Sweden

  • Yuji Miyahara. Functional gate-field effect transistors for electrically neutral molecules. Matrafured 2017 2017.06.13 Thermal Hotel Visegrad Superior, Budapest, Hungary

  • Yuji Miyahara. Exploring Fusion between Life Science and Electronics. 1st International Symposium on Precision Medicine and Biomedical Technologies 2017.06.03 Carp City Hotel, Quanzhou, China

  • Miyahara Y. Semiconductor devices for biomedical applications. The 3 rd Joint Symposium between IBB/TMDU and Chulalongkorn University on “Biomedical Materials and Engineering” 2016.12.15 Bangkok, Thai

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Patents 【 display / non-display

  • Phenylboronic acid monomer and phenylboronic acid polymer

    Patent Number: 5622188

Awards & Honors 【 display / non-display

  • The Yamazaki Teiichi Prize, Foundation for Promotion of Material Science and Technology of Japan (2006),2006

  • The Prize of Progress, The Institute of Electrical Engineers of Japan (2005),2005

 

Campus class subject 【 display / non-display

  • Bio-intelligence Science