Personnel Information

写真a

KANAI Masami


Job title

Professor

Homepage URL

http://www.tmd-cea.jp/eam/

Research Areas, Keywords

Experimental Animal Model for Human Disease

Graduating School 【 display / non-display

  • Osaka Prefecture University, Faculty of Agriculture, Veterinary Sciene, 1988, Graduated

Graduate School 【 display / non-display

  • The University of Tokyo, Graduate School, Division of Agricultural Science, Veterinary Sciene, Doctor's Course, 1992.03, Completed

Degree 【 display / non-display

  • PhD, The University of Tokyo

Campus Career 【 display / non-display

  • 2010.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Experimental Animal Model for Human Disease, Professor
  • 2010.04
    -
    2014.09
    Tokyo Medical and Dental University, Joint Institutes for Education and Research, Center for Experimental Animal, Ceter for Experimental Animals, Professor
  • 2014.10
    -
    2017.03
    Tokyo Medical and Dental University, Research and Industry-University Alliance Organization, Center for Experimental Animal, Professor
  • 2017.04
     
     
    Tokyo Medical and Dental University, Institute of Research, Research Facility Cluster, Center for Experimental Animal, Professor
  • 2017.05
    -
    2019.08
    Tokyo Medical and Dental University, Institute of Research, Research Facility Cluster, Center for Experimental Animal, Professor

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Research Areas 【 display / non-display

  • General anatomy (including histology/embryology)

 

Published Papers & Misc 【 display / non-display

  • Rie Saba, Keiko Kitajima, Lucille Rainbow, Silvia Engert, Mami Uemura, Hidekazu Ishida, Ioannis Kokkinopoulos, Yasunori Shintani, Shigeru Miyagawa, Yoshiakira Kanai, Masami Kanai-Azuma, Peter Koopman, Chikara Meno, John Kenny, Heiko Lickert, Yumiko Saga, Ken Suzuki, Yoshiki Sawa, Kenta Yashiro. Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice. Sci Rep. 2019.08; 9 (1): 11953. ( PubMed, DOI )

  • Risa Nomura, Kenichi Kashimada, Hitomi Suzuki, Liang Zhao, Atsumi Tsuji-Hosokawa, Hideo Yagita, Masatoshi Takagi, Yoshiakira Kanai, Josephine Bowles, Peter Koopman, Masami Kanai-Azuma, Tomohiro Morio. Nr5a1 suppression during the murine fetal period optimizes ovarian development by fine-tuning Notch signaling. J. Cell. Sci.. 2019.04; 132 (8): ( PubMed, DOI )

  • Hirate Y, Hayakawa K, Nakano Y, Uemura M, Miura K, Kanai Y, Kanai-Azuma M. Identification of downstream genes of the uterine SOX17 around the receptive period(和訳中) Experimental Animals. 2018.07; 67 (Suppl.): S67. ( ichushi )

  • Miura K, Harikae K, Nakaguch M, Imaimatsu K, Hiramatsu R, Tomita A, Hirate Y, Kanai-Azuma M, Kurohmaru M, Ogura A, Kanai Y. Molecular and genetic characterization of partial masculinization in embryonic ovaries grafted into male nude mice. PLoS ONE. 2019; 14 (3): e0212367. ( PubMed, DOI )

  • Igarashi H, Uemura M, Hiramatsu R, Hiramatsu R, Segami S, Pattarapanawan M, Hirate Y, Yoshimura Y, Hashimoto H, Higashiyama H, Sumitomo H, Kurohmaru M, Saijoh Y, Suemizu H, Kanai-Azuma M, Kanai Y. Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk. Biol. Reprod. 2018.09; 99 (3): 578-589. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Masami Kanai-Azuma. Mouse model of human female infertility. 第8回日本・中国・韓国マウスリソースワークショップ 2019.08.26 つくば(理化学研究所バイオリソース研究センター内)

  • Yoshikazu Hirate,Hitomi Takahashi,Yoshiaki ito,Jilnling Li,Chiho Ohtsuka,Hiroshi Asahara,Ruby Yanru Chen-tsai,Masami Kanai-Azuma. Site-diected transgenic mice production using TARGATTtmKnock-in technology in TMDU. 15th TRANSGENIC TECHNOLOGY MEETING 2019.04.07 神戸国際会議場

  • Kanai-Auzma M. Interaction between embryo and endometrium during implantation process. The 41st Annual Meeting of the Molecular Biology Society of Japan, Workshops[New perspectives on mammalian embryonic development] 2018.11.28 Pacifico Yokohama

  • Okano T, Cho K, Kawamura S, Onai N, Fujii W, Kakuta S, Kanai-Azuma M, Ohteki T, Imai K, Kanegane H, Otsu M, Ariga T and Morio T. Infantile onset pulmonary alveolar proteinosis with hypogammaglobulinemia caused by heterozygous mutations of 2'-5'-oligoadenylate synthase 1 (OAS1). The 18th Biennial Meeting 2018.10.24 Lisbon, Portugal

  • Hirate Y, Hayakawa K, Nakano Y, Uemura M, Miura K, Kanai Y, Kanai-Azuma M. Identification of downstream genes of the uterine SOX17 around the receptive period. The 65th Annual Meeting of Japanese Association for Laboratory Animal Science 2018.05.17 Toyama Prefectural Civic Center

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